口腔診斷學 陳玉昆副教授 : 高雄醫學大學 口腔病理科 07-3121101~2755...
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口腔診斷學
陳玉昆副教授 : 高雄醫學大學 口腔病理科 07-3121101~2755 [email protected]
Intraoral brown, bluish and black conditions
口腔棕色、藍色、黑色疾病
Understanding:1. Intraoral brown, bluish and black conditions
學 習 目 標學 習 目 標
1. Kaohsiung Medical University, Oral Pathology Department2. Cawson RA: Oral Diseases. 3rd Ed., pp. 11.2-11.103. Cawson RA: Oral Diseases. 3rd Ed., pp. 11.124. Cawson RA: Oral Diseases. 3rd Ed., pp. 11.135. AFIP (American air-force institute of pathology)
References:References:
參考資料
Melanin
Blood
Ref. 1
Hairytongue
Localized
pigmented
Endocrine
disorder
Brownish, BlackishPigmented Lesions
Exogenous Endogenous
Melanocyte Stimulating Hormone
Tyrosinase
Ref. 2
Intraoral brown and black conditions
Normal Lentigo simplex Junctional activity
Compound nevus Intramucosal nevus Blue nevus
Ref. 2
Intraoral brown and black conditions
Junctional activity
Intramucosal nevus
Compound nevusIntraoral Cutaneous
Liminapropria
Refs. 1, 2
Intraoral brown and black conditions
Epithelium
Pigmentedbasalcell
Melanophage
Pigmentedbasal
keratinocyte
Refs. 1, 2
Intraoral brown and black conditions
Oral Melanotic Macule
Amalgam Tatto
Amalgam restoration
Amalgam retrograde filling
Refs. 1, 3
Intraoral brown and black conditions
Graphite Tatto
Ref. 1
Intraoral brown and black conditions
Hairy Tongue
Ref. 1
Intraoral brown and black conditions
Early Changes of Melanoma1. Appear recently2. Change in degree of pigmentation 3. Bleeding or ulceration4. Rapid growth (in size or elevated)
Refs. 1, 2
Melanoma
Ref. 1
Melanoma
Ref. 1
Melanoma
Ref. 1
Melanoma
Ref. 1
Melanoma
Ref. 1
Immunohistochemical staining of HMB-45 (A) and S-100 (B) revealed diffuse positivity in the tumor cells.
Von Reclinghausen’s disease of skinmultiple neurofibroma
Cafa-Au-Lait-spot
Ref. 5
Cafa-Au-Lait-spot
Ref. 1
Addison’s Disease
Pituitary Gland
ACTH
Gluco-cortisoid (Hydrocortisone)
Blood circulation
product
Cause adrenal produce
Into
Ref. 4
Peutz-Jeghers Syndrome
Bluish black macules
Skin pigment but not oral tends fade with age
Intestinal polyp
Refs. 1
Hemangioma Mucocele
Eruption cystHematoma
Bluish Lesions
Ref. 1
Varicoses
Ref. 1
Mucoepidermoid Carcinoma
Ref. 1
Knowing how to differentiatebrown, bluish & black oral conditions
SUMMARY