:¦: : : 2$³6 b1 ' b.b b bn ' . a b p ¨(» b. øb?b Ç5À123 日補綴会誌...

─ 122 ─

日補綴会誌　8・125回特別号，2016第1日　第 3会場一般口演発表

─ 122 ─

2

Effect of occlusal contact state in two occlusal force on masticatory performance

Sugiyama S, Okazaki S, Hirai H, Yoshioka F, Sato T, Nomura K, Hoshiai K, Ozawa S, Takebe J

Department of Removable Prosthodontics, School of Dentistry, Aichi Gakuin University

1

60

BS

Light Clenching

LC

Heavy Clenching HC

BS

BE

10 m 50 m

BS

A

B

C

30

2

Spearman

10 MVC 30 MVC

BS

ABC

B A C

1

2015 25(2) 59-65

2

FFI

. 2013 ; 218 : 234-240.

─ 123 ─

日補綴会誌　8・125回特別号，2016 第1日　第 3会場一般口演発表

─ 123 ─

1

Masticatory performance of elderly dentate persons

Yamamoto S, Nakajima K, Shiga H, Uesugi H, Komino M, Tanaka T, Oki J, Fujii S, Sonezaki T,

Nakano Y

Department of Partial and Complete Denture, The Nippon Dental University School of Life Dentistry at

Tokyo.

1 2

3

NDU T2012 29

65

157 27 130 72 7

Sato 1 20

Koshino 2 25 44

Sato 1

MS1 Koshino 2

MS2 44

20 20

5

MS3

20 10 ml

MS1 MS2 MS3

3

Pearson

1

MS1 MS2 MS3

2

MS1 MS2 MS3

3 3 2

3

4

1 Sato Y, Minagi S, Akagawa Y, Nagasawa T. An

evaluation of chewing function of complete

denture wearers. J Prosthet Dent 1989; 62: 50-53.

2 Koshino H, Hirai T, Toyoshita Y, Yokoyama Y,

Tanaka M, Iwasaki K, et al. Development of

new food intake questionnaire method for

evaluating the ability of mastication in complete

denture wearers. Prosthodont Res Pract 2008; 7:

12-18.

3 Shiga H, Ishikawa A, Nakajima K, Tanaka A.

Relationship between masticatory performance

using a gummy jelly and food intake ability in

Japanese complete denture wearers. Odontology

2015; 103: 356-9.

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─ 124 ─

1

Relationship between physical condition and masticatory performance in elderly adults

Kuramochi A, Nakajima K, Shiga H, Okada Y, Yokoyama M, Tanaka T, Fujii S, Nanba N, Komatsu Y,

Naitoh T

Department of Partial and Complete Denture, The Nippon Dental University School of Life Dentistry at

Tokyo.

1

1 2

NDU T2012 29

1

70 134 41 93

2

20

10 ml

SPSS for Windows 10

0J SPSS Chicago IL USA

Pearson

independent t

test

1

2

3

1 .

ADL QOL

. 2011; 7: 25-34.

2

.

Health Research

Volunteer Study .

2013; 40(3): 390-398.

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─ 125 ─

Effects of Masticatory Movemnets on Sitting and Foot Sole Pressures during Sitting Posture

Chino K, Sakaguchi K, Yokoyama A

Department of Oral Functional Prosthodontics, Division of Oral Functional Science, Graduate School of

Dental Medicine, Hokkaido University

10

3

90

90

20

CONFORMat®

®

2015

5

1

1 20

2

20

p 0 05

3 3

4

20

p 0 05

2

1 20

2

20

p 0 05

3 3

4

20

p 0 05

20

─ 126 ─


─ 126 ─

Over time influence of jelly texture on tongue pressure in squeezing

Tokuda Y1), Ono T2), Hori K2), Hujiwara S2), Minagi Y1), Murakami K1), Maeda Y1)

1)Department of Prosthodontics, Gerodontology and Oral Rehabilitation, Osaka University Graduate School

of Dentistry, 2)Division of Comprehensive Prosthodontics , Niigata University Graduate School of Medical

and Dental Science

1 2

5

7 28 0 3 7

9 5ml 1

Initial squeeze Last squeeze

Middle squeeze

Swallow

Tukey

Initial squeeze Middle squeeze

1

2 Initial squeeze

3

90

Last squeeze Swallow

20 37 3 4

1 Ishihara S, Nakao S, Nakamura M, et al.

Compression test of food gels on artificial

tongue and its comparison with human test. J

Tex Stud, 2013; 44:104-114

2 Yokoyama S, Hori K, Tamine K, et al. Tongue

pressure modulation for initial gel consistency in

a different oral strategy. Plos One, 2014; 18:

e91920.

1

1 4

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─ 127 ─

Team approach of Swallowing center in Tohoku University Hospital and Survey of Dysphagia

Ishiko R1,2), Koyama S1,2), Kato K3), Katori Y3), Sasaki K2)

1)Maxillofacial Prosthetics Clinic, Tohoku University Hospital, 2)Division of Advanced Prosthetic Dentistry,

Tohoku University Graduate School of Dentistry, 3)Otolaryngology-Head and Neck Surgery, Tohoku

University Hospital

PAP

2015 10

2015 10 2016 1

81

3

LIFE Saitama Japan JMS

JMS Hiroshima Japan

52 65 19 84

65 6 36 16

59 6 5 8 34 6

3 2 9

7 29 0 6 5 25 8

16 1 9 7

28 3

45 6 21 1

43 8

37 5

49 0

19 9 13 1 5

21 6

RSST

─ 128 ─


─ 128 ─

Periodontal Disease Is Associated with Insomnia among Victims of the Great East Japan Earthquake.

Tsuchiya M1), Hagiwara Y2), Watanabe Y3), Watanabe Y1)

1)Kansei Fukushi Research Institute, Tohoku Fukushi University, 2)Division of Orthopaedica Surgery,

Tohoku University, 3)Faculty of Genral Maneagement, Tohoku Fukushi University

2011 3 11

1

2

2011 2013 2011 6

4

H24 002

8 015 18

31 009 36

8

10

Athens Insomnia Scale

6

3

BMI

Kesselar K6

PTSR

STATA Ver 13 1

OR 95 CI

P 0 05

2 892 38 9

6 5 7 1

6 3 3 9 3 9 3 2

OR 2 16 95 CI 1 43 3 26 p 0

001 OR 2 22 95 CI 1 40 3 51 p 0 01

p 0 45

K6 PTSR

1 Ishigaki A, et al., Tohoku J Exp Med. 229(4):

287-99, 2013.

2 Al-Jewair TS, et al., Sleep Breath 19:1111-20,

2015.

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─ 129 ─

Mechanism of Xerostomia Induced by Diabetes Mellitus

Munemasa T1), Kondo Y1), Mukaibo T1), Kusuda Y1), Miyagi Y1), Tsuka S1), Masaki C1), Nakamoto T2),

Hosokawa R1)

1)Department of Oral Reconstruction and Rehabilitation, Kyushu Dental University, 2)Department of

Prosthodontics, Matsumoto Dental University

2

KK Ay

KK Ay

C57Bl 6J

ex vivo

Carbachol CCh 0 3μM

Na Cl

7000

8

VHX 5000 KEYENCE

HE

Aquaporin5

AQP5 Na K 2Cl

NKCC1

TMEM16A

Ca2 Fura 2

CCh Ca2

KK Ay

KK Ay

KK Ay

AQP5 NKCC1 TMEM16A

Ca2 KK Ay

KK Ay

Na Cl

1

2

─ 130 ─


─ 130 ─

Basic observation of salivary properties related to the prosthetic treatment

Kawanishi N1), Hoshi N1), Saita M1), Arai Y1), Sugimoto M2), Kimoto K1)

1)Division of Prosthodontics & Oral Rehabilitation Department of Oral Function and Restoration, Graduate

School of Dentistry Kanagawa Dental University, 2)Institute for Advanced Biosciences, Keio University

13

9 00

13 00 17 00 1 3

3

4 2 5

−CE MS

No 260

Score plots 1

Loading plots 2

1 Sugimoto M, Wong D.T., Hirayama A, Soga T, &

Tomita M. Physiological and environmental

parameters associated with mass spectrum-based

salivary metabolomics profile. Metabolomics, 9 ,

454 - 63

1 : Score plots

2 : Loading Plots

─ 131 ─


─ 131 ─

GLP 1

The state of feed changes serection of GLP-1 in healthy mice

Kan Y1), Toyoshita Y1), Sasaki M1), Kawanishi K1), Aita H1), Yamanaka T2), Ashida S2), Konishi Y2),

Takasaki H2), Ito Y2), Koshino H1)

1)Department of Oral Rehabilitation, School of Dentistry, Health Sciences University of Hokkaido, 2)

Tohoku-Hokkaido Branch

1 GLP 1

1

GLP 1 L

GLP 1

GLP 1

16 c57BL 6J 60

24

2 kcal

30 60 90

120 GLP 1 DPP 4

GLP 1

GLP 1 GLP 1 active form assay kit

GLP 1

2 24 5

0 01 mg kg

30

GLP 1

SPSS Mann Whitney U

p 0 05

GLP 1 30

62 2 7 3 pmol l 44 1 5 4

pmol l

p 0 05 1

GLP 1

1 Janssen P, Rotondo A, Mulé F, et al. A

comparison of glucagon-like peptides 1 and 2.

Aliment Pharmacol Ther 2013 37 18-36

GLP-1

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─ 132 ─

BMP 7

Elucidation of the function of BMP-7 in the oral epithelium

Nishio K1), Urata K1), Ito R2), Maruno M2), Okada S2), Ariwa Y1), Yamazaki A1), Gionhaku N1)

1)Department of Complete Denture Prosthodontics, Nihon University School of Dentistry,, 2)Division of

Applied Oral Sciences, Nihon University Graduate School of Dentistry

Bone morphogenetic protein BMP1

BMP

BMP 72

BMP 3

BMP 7

Ca9 22

HSC 3 BMP 7

RT PCR

Ca9 22 HSC 3 rhBMP 7 50

100 250ng ml BMP

Smad1 5 8

western blot BMP 7

Ca9 22 rhBMP 7 100ng

ml 1

IL 17F real time PCR

IL 17F

ELISA

BMP Ca9 22 HSC3

ALK2 3 6

BMPR2 ACVR2

rhBMP 7 Smad1 5 8

Ca9 22 100ng ml

Ca9 22

rhBMP 7 BMP

IL 17F

rhBMP 7 1 2

IL17F

BMP 7

DM3189

IL17F IL17F

rhBMP 7

IL17F

4

IL 17F

BMP 7

1 Bone

morphogenetic protein (BMP)

2002 102 (10) 764-761

2 Yanagita M Oka M Watanabe T et al

USAG-1: a bone morphogenetic protein

antagonist abundantly expressed in the kidney

Biochem Biophys Res Commun 2004 Apr 2

316(2) 490-500

3

in vitro BMP

1997 16

(1) 159

4 Saijo S Ikeda S Yamabe K et al Dectin-2

recognition of alpha-mannans and induction of

Th17 cell differentiation is essential for host

defense against Candida albicans Immunity

2010 32 (5) 681-691

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─ 133 ─

A pilot study for measurments of soft and hard tissue thickness by using compact ultrasound probe.

Anzai M1,2), Maruo K1), Hoshi N1), Kimoto K1)

1)Division of Prosthodontics & Oral Rehabilitation Department of Oral Function and Restoration, Graduate

School of Dentistry Kanagawa Dental University, 2)Anzai dental office

1 2 X

CBCT

10

3

0mm

10

2 0mm 4 0mm 6 0mm

paired t

1 Fabrice CP, Juliana M, Stefan W, Joachim T,

Klaus R, Stefan H. High-frequency ultrasound as

an option for scanning of prepared teeth: an in

vitro study. Ultrasound in Med & Biol 2015; 41:

309–316.

2 Khalid HS, Nigel LB, Diana LG, Joseph AE. In

vitro enamel thickness measurments with

ultrasound. Ultrasound in Med & Biol 2015; 41:

301–308.

:

:

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─ 134 ─

Influence of Maximun Occlusal Force and Gum Amount on Mental Stress Release by Chewing

Saitou Y1), Tasaka A2), Unno W1), Ikeda K2), Aoki T1), Kikuchi M1), Nakanishi K1), Ueda T1), Yamashita S2),

Sakurai K1)

1)Department of Removable Prosthodontics and Gerodontology, Tokyo Dental College, 2)Department of

Removable Partial Prosthodontics, Tokyo Dental College

Tahara

1

2 12

16 28 3 2 2

30 30

10

10

1 2

1g Rotte

10

Salivette SARSTED

RIA ME3000P

Mega Electronics

10

GM10

5

30

Bonferroni

t

0 05

10

1

1 1

2 2

10 1

2

513 7 148N 1

2

r 0 501 P 0

048

2 1

1

2

1 Tahara Y, Sakurai K, Ando T. Influence of

Chewing and Clenching on Salivary Cortisol

Levels as an Indicator of Stress. J Prosthodont

2007; 16: 129-135.

2

7 124

2015 148

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─ 135 ─

Shurenkai

Examination of occlusal force and occlusal contact area from main occluding area

Nakamura K1), Yamamoto M1), Kuno S1), Zennami T1), Terao Y1), Nagae T1), Matsuo T1), Mori K1),

Yamamura M1), Onozawa H2)

1)Shurenkai, 2)GC Co.

1

5 5mm

3mm 7mm2

1

100 21 79 18 72 30 5

3

1 3

4mm 4 0mm

1

3

18mm

1

BE I

Shoot mode

60

2

1

DePROS

50H R L2

709

1

108 7N SD 220 3 69 6N SD 53 8

89 2N SD 161 1

2

2 7mm2 SD 1 6 2 1mm2 SD 1 6

2 4mm2 SD 1 6

3

6 6mm2 SD 4 3 6 6mm2 SD 5 3 6 6mm2

SD 4 8

1

2010

2

2003

─ 136 ─


─ 136 ─

MRI

Shurenkai

Displacement of temporomandibular joint during bruxism movement to deglutition using ultra-high-speed

MRI

Higashi T, Nakamura K, Yamamoto M, Gaijo E, Sakai Y, Takahama S, Tomizawa O, Funaki H

Shurenkai

MR

MRI

1

MRI

NA

1 34

UA 1 39 2

MRI Acheiva Nova Dual 1 5T

47mm Surface Microscopy Coil

Balanced FFE

50 100

FH

50

DICOM

OsiriX2 OsiriX

CC

CL GR

TA

5

Dunnett

MRI

1

2 NA CL GR

CC

CC

3 UA GR

CC

CC

1mm

1

MRI

2015 7 124

143

─ 137 ─


─ 137 ─

H W Lang

Shurenkai

Trace of masticatory movement path and lateral mandibular translation path at horizontal plane view

- Investigation of the same trace subjects -

Tomita S1), Nakamura K1), Yamamoto M1), Ota S1), Okashita K1), Sato M1), Yutani M1), Hosokawa T2),

Lang H2), Onozawa H3)

1)Shurenkai, 2)KaVo Dental Systems Japan Co., Ltd., 3)GC Co.

124

6 91

2

7 3 54 68 59 3

4 22 50 37 8

ARCUSdigma

Motion Analysis

1 2

1 3 0mm

KaVo

integrated Desktop

1

BE I

7 6 2

1

2

3

4 U

5

6 3 38mm SD 0 69

7 35 2mm2 SD 14 5

1

2015 7 124 267

2

1997

166-167

─ 138 ─


─ 138 ─

CAD CAM

JeisonCARBAJAL

Fracture behaviors and strengths of hybrid resin molar crown restorations fabricated with CAD/CAM

system

Kaname T, Wakabayashi K, Shiomi S, Carbajal J, Nakamura T, Yatani H

Department of Fixed Prosthodontics, Osaka University Graduate School of Dentistry

CAD CAM

CAD CAM

CAD CAM

1 CAD CAM

CAD CAM

CAD CAM

120 CAD CAM

CAD CAM

HC HC

CERASMART GC CS KZR CAD HR

2 YAMAKIN KZR ENAMIC Vita

EN AVENCIA AV 5

IPS e max CAD Ivoclar Vivadent

EMAX CAD

20

120

20

10 24 10

37 30

Autograph AGS 500D

8 mm

0 5 mm min

2

PHANTOM V10 Nobby Tech 9 411

VW 6000 KEYENCE 1 000

2

1

CAD CAM CAD CAM

1 1 200 N 1

2 400 N

24 HC

1 963 N CS 2 361 N KZR 2 693 N EN

1 936 N AV 3 140 N EMAX 2 345 N

30

HC 922 N CS 1 892 N KZR 2 245

N EN 1 949 N AV 2 488 N EMAX 2

479 N HC CS KZR AV 24

30

P 0 05

CAD CAM

CAD CAM

CAD CAM

CAD CAM

1 Potency DJ, Klim J. CAD/CAM in-office

technology: innovations after 25 years for

predictable, esthetic outcomes. J Am Dent Assoc,

2010; 141: 5S-9S

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─ 139 ─

CAD CAM CAD CAM

Evaluation of surface texture of CAD/CAM crown among various types of CAD/CAM milling system.

Koshihara T1), Hara M1), Sato T1), Hayashibara T1), Masuda T1), Shinya A1), Takuma Y1), Yotsuya M1),

Takahashi T2), Doshita S3)

1)Department of Fixed Prosthodontics, Tokyo Dental College, 2)Division of General Dentistry, Tokyo

Dental College Chiba hospital, 3)ATOM CORPORATION

21

26 CAD CAM1 CAD CAM

CAD CAM CAD CAM

CAD CAM

6 CAD

CAM 2 92

CAD CAM

3

CAD CAM 4

CAD CAM

CAD CAM

CAD CAM

Lava™ Ultimate 3M ESPE

PRODIA M45 PRODIA DWX 50 Roland

BELLEZZA 4X MILLING MACHINE i CAST

CAD CAM CAD CAM

CAD

CAD CAM 3D SEM

500 3

Sa

CAD CAM

CAD CAM

1 :

CAD/CAM

.

, 1:64-70, 2009.

2 : CAD/CAM .

, 34:25-26, 2015.

3 : CAD/CAM

. , 29:3-8, 2015.

4 : CAD/CAM CAD/

CAM , CAD/

CAM , pp44-50. ,

, 2014.

CAD/CAM CAD/CAM

─ 140 ─


─ 140 ─

CAD CAM

Ball-on-disk wear analysis of paired CAD/CAM machinable ceramics

Handa K1), Murakami N1), Takahashi H2), Wakabayashi N1)

1)Removable Partial Prosthodontics, Department of Masticatory Function Rehabilitation, Division of Oral

Health Sciences, Graduate School, Tokyo Medical and Dental University, 2)Oral Biomaterials Engineering,

Course of Oral Health Engineering, School of Oral Health Care Sciences, Tokyo Medical and Dental

University

CAD CAM 3

VITABLOCS Mark VITA

Zahnfabrik MK VITA

ENAMIC VITA Zahnfabrik EN

IPS e max CAD Ivoclar Vivadent EX

4mm

8mm 2mm

1 36

50N

15 3 7mm 1

2Hz 3000 1000

CEREC Omnicam Sirona 3

Geomagic Studio 3D Systems

ANSYS 11 0 ANSYS

1 1

MK

EN EX

MK EX

EN

1 Koottathape N, Takahashi H, Iwasaki N,

Kanehira M, Finger WJ. Two- and three-body

wear of composite resins. Dent Mater. 2012;28:

1261-1270

1

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─ 141 ─

12

Investigation of pontic design using 12% gold-silver-palladium alloys.

Kawashita K

Tokai Branch

3

14K

320

3

3

PMMA

1 2

1996.277-296.

2

1 2 1993.29-30.

3 26 4

2014.356-357

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─ 142 ─

Fracture strength of a multi-layered zirconia material

Ueda K1), Seto M1), Katsuta Y2), Ozawa M2), Watanabe F2)

1)Oral Implant Care Unit, The Nippon Dental Univ. Niigata Hospital, 2)Dept. of Crown & Bridge

Prosthodontics, The Nippon Dental Univ. School of Life Dentistry at Niigata

CAD CAM

ML ML1

4

ML 4

6 ISO6872

25 0mm 4mm 2mm

800

AG Shimadzu

15mm 0 1mm

min 3

3 1053 65MPa2

ML

ML

1 Ueda K, Güth JF, Erdelt K, Stimmelmayr M,

Kappert H, Beuer F: Light Transmittance by a

Multi-coloured Zirconia Material, Dent Mater J,

34(3): 310-314, 2015.

2 , :

, ,33:313-320,2014

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─ 143 ─

3

Three-year follow-up survey of the monolithic zirconia Crown

Takaesu Y, Matuura T, Sato H

Department of Oral Rehabilitation, Section of Fixed Prosthodontics, Fukuoka Dental College

CAD CAM

CAD CAM

2011

2011 4 2015 2

ZENOSTAR WIELAND DENTAL®

16 23

CDA quality evaluation system

Smith and

Knight tooth wear index 3

10

250

6 23 1

1

1 Quality evaluation for dental care : guidelines

for the assessment of clinical quality and

professional

performance.Sacramento,Calif. :California Dent

al Association, 1977.

CDA quality evaluation system California Dental

Association, 1977

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─ 144 ─

A Case Report of Lock Denture Applied a Zirconia Wing

Oya K1), Yamaga T2)

1)a branch of Kansai, 2)a branch of Kansai

2013 11

63

FMC

B4

2

B4

12

1

1993 38 2 535-541

2

BLK

2000

28(10) 1258-1271

─ 145 ─


─ 145 ─

A case report of speech aid prosthesis using nasopharyngeal endoscopy

Tamada Y1), Furuya J2), Nomura T1), Murakami T1), Itsukaichi A1), Kondo H1)

1)Department of Prosthodontics and Oral Implantology,School of Dentistry,Iwate Medical University, 2)

Department of Oral Health Care Science for Community and Welfare,Graduate School of Medical and

Dental Sciences,Tokyo Medical and Dental University

1

48

1992

2009

2015

Blowing

2

3

4

1

1 Gibbons,P., Bloomer,H.:A supportative-type

prosthetic speech aid. J. Pros. Dent., 8:362-369,

1958.

1 VAS

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─ 146 ─

A Case Report:A Maxillary Implant Overdenture

Kishimoto M

Oita City Kishimoto Dental Office

1990 9 42

44 45 46 47

2008 3 44 45 46 47 Screw

VentMTX 11 PFM

2009 3 24 27 1 Swiss Plus

3 7 8mm

MTI 1 2 14mm 4

2009 4 9

2011 9 26

16 15 14

2012 2

26 2012 3 14 17 27 2

Screw VentHA 4 7 5

24 6 25 2

Screw VentHA 3 7 8mm

2013 2 17 14 25 27

QOL

4 2

8mm

3 7mm

2 2

1 .

. 30 44 51,

2016.

2 .

. 75:41

52 2015.

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─ 147 ─

SB RMMA

Physiologic factor about the RMMA occurrence after the respiratory in the SB subjects.

Tsujisaka A1), Haraki S1), Mizumori T1), Yatani H1), Kato T2)

1)Department of Fixed Prosthodontics, Graduate School of Dentistry, Osaka University, Osaka, Japan, 2)

Department of Oral Anatomy and Neurobiology, Graduate School of Dentistry

sleep bruxism SB

rhythmic masticatory muscle

activity RMMA

arousal

obstructive sleep

apnea OSA

arousal

SB OSA OSA SB

SB OSA

OSA

SB OSA

SB OSA

SB

RMMA

1

Polysomnography PSG

RMMA RMMA index 4

SB 22

PSG 2

Pittsburgh sleep quality index Epworth

sleepiness scale SB OSA

2 RMMA

2

apnea hypopnea index

AHI RMMA

RMMA index

AHI 5 SB AHI 5 SB

OSA

3 RMMA

RMMA

10 RMMA

2

10 RMMA

AHI SB

OSA arousal RMMA

4

Fisher Mann Whitney U

Wilcoxon Pearson

0 05

SB OSA SB

RMMA index SB OSA

2 RMMA 70

Stage N1 Stage N2

40 Stage REM RMMA 10 9

10

Stage N1 Stage N2 RMMA index

AHI SB OSA

arousal 15 3

RMMA arousal RMMA

Stage

N1 Stage N2

arousal RMMA

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─ 148 ─

Study of pain tolerance threshold by applying an electrical stimulus on the alveolar ridge

Nakashima Y1), Furuse N2), Ogawa T2), Koide Y1), Suemitsu H1), Igarashi K2), Kimura J1), Shiba R1),

Fukui S1), Ookubo M1), Gunji A1), Kimoto S1), Kawai Y1)

1)Removable Prothodontics, Nihon University School of Dentistry at Matsudo, 2)Removable Prothodontics,

Nihon University Graduate School of Dentistry at Matsudo

1

1

C A

Pain Tolerance Threshold PTT

Neurometer CPT C®

Neurotron Inc

Baltimore MD USA N CPT C

N CPT C

51 58 7 49 60 7

N CPT C

5Hz C

250Hz A 2

PTT

Erkodur®

Erkodent Inc Baden Württemberg Germany

PTT

Mann Whitney U test PTT

Spearman rank correlation PTT

Kruskal Wallis test

Mann Whitney Utest

5Hz PTT

PTT r

0 33 p 0 017 250Hz PTT

2

PTT

PTT

PTT

1 Carlsson GE, Omar R. The future of complete

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Journal of oral rehabilitation. 2010;37(2):143-56.

Epub 2009/12/17

2 Riley JL, 3rd, Robinson ME, Wise EA, Myers

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Jaw and neck muscle activities of jaw closing dystonia in chewing

Ishii T1), Narita N1,2), Endo H3), Kamiya K1), Hirayama T2)

1)Department of Removable Prosthodontics, Nihon University School of Dentistry at Matsudo, 2)

Department of Neurlogical Surgery, Nihon University School of Medicine, 3)Human Technology Research

Institute, National Institute of Advanced Industrial Science and Technology (AIST)

8 3 5

56 1 8 6 2

44 5

EC 14 13 010 1

1

POLYGRAPH BIOELECTRIC AMPL

MKG K7I

PC MultiScope

EMG Ver1 8 Medical Try System

Gain Phase

Coherence

Two way repeated

measured ANOVA Bonferroni t test

Mann Whitney Rank Sum test

1 Power

2 Power

3 Gain

Gain

4 Phase

5

Coherence

Power

Gain

Coherence

1 Bakke M, Møller E, Thomsen CE, Dalager T,

Werdelin LM. Chewing in patients with severe

neurological impairment. Arch Oral Biol. 2007

Apr;52(4):399-403.

2 Bakke M, Werdelin LM, Dalager T, Fuglsang-

Frederiksen A, Prytz S, Møller E. Reduced jaw

opening from paradoxical activity of mandibular

elevator muscles treated with botulinum toxin.

Eur J Neurol. 2003 Nov;10(6):695-9.

─ 150 ─


─ 150 ─

Immune tolerance and its underlying mechanism induced by host bone-marrow-derived mesenchymal stem

cells after long bone injury

Komi K1), Akiyama K1), Yoshioka Y1), Kunitomo M1), Komori T1), Kunitomo Y1), Ono M2), Maekawa K1),

Kuboki T1)

1)Department of Rehabilitation and Regenerative Medicine, Okayama University Graduate School of

Medicine, Dentistry and Pharmaceutical Sciences, 2)Department of Molecular Biology and Biochemistry,

Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

1

2

C57BL 6J

1 0mm

1 3 5 7

HE CD146

TNF

CD146 CD90 Sca 1

T

Il1b Il6 Ifng TnfaRT PCR

in vitro TNF

mBMSCs

CD146

MTS

TNF mBMSCs

FasL

T T

T

1

In vitroTNF mBMSCs

TNF

FasL T

T

1 Liu Y, Wang L, et al. Mesenchymal stem cell-

based tissue regeneration is governed by

recipient T lymphocytes via IFN and TNF

Nature Medicine 2011; 17: 1594-1601.

2 Aikawa E, Fujita R et al. Systemic high-mobility

group box 1 administration suppresses skin

inflammation by inducing an accumulation of

PDGFR mesenchymal cells from bone

marrow. Scientific Report 2015; 5: 11008.

─ 151 ─


─ 151 ─

Bone regeneration with Functional specialized priming cell coctail

Akiba Y, Eguchi K, Akiba N, Uoshima K

Division of Bio-Prosthodontics, Niigata University Graduate School of Medical and Dental Sciences

4 SD GFP

BMSC IL 8

VEGF

Valproic acid VPA

GFP 72 1

FACS

12 SD 5

4 μCT

1 Runx2 1vs1 43

Angpt1 1vs1 3 VPA

Runx2 1vs2 26 Angpt1 1vs2 06 Cxcl12

1vs1 55 Vegf 1vs0

8vs1 05 IL 8

Vegf 1vs2 01 IL 8

VPA 1vs2 3

VPA1 1vs2 3vs3 1

CT

VPA

FACS

Runx2 1vs1 2

Angpt1 1vs1 5 Cxcl12 1vs1 4 Vegf 1vs1 3

─ 152 ─


─ 152 ─

Magnetic field activated ostogenic capability of dental pulp stem cell for bone generation

Hata M1), Omi M1), Fukuzawa R1), Kojima N1), Naruse K2), Ozawa S1), Matsubara T2), Takebe J1)

1)Department of Removable Prosthodontics, School of Dentistry, Aichi Gakuin University, 2)Department of

Internal Medicine, School of Dentistry, Aichi Gakuin University

1

2

3

6 SD

dental pulp stem cells

DPSCs

1

1 CD29 CD34 CD45 CD49d

CD90

2

Oil red O

FABP 4 ALP Osteocalcin

2

DPSCs 6well

0 4T 0 17Hz

6

MTT assay

ALP Osteocalcin

Alizalin Red S

DPSCs CD29 CD49d CD90

positive CD34 CD45 negative

DPSCs

control

1 Liu, J., et al., Concise reviews: Characteristics

and potential applications of human dental tissue-

derived mesenchymal stem cells. Stem Cells,

2015. 33(3): 627-638.

2 Bassett CA Mitchell SN Gaston SR

Treatment of ununited tibial diaphyseal fractures

with pulsing electromagnetic fields J Bone Joint

Surg Am. 1981. 63(4):511-523.

3 Fukuzawa R, Ozawa S, Anuudari E et al.

Different Responses of Osteoblasts and

Fibroblasts to a Changing Magnetic Field.

Journal of Hard Tissue Biology. 2013 22(2):

183-188

─ 153 ─


─ 153 ─

iPS

PKC

Effects of PKC inhibitor in the osteoblastic differentiation of a mesenchyma system stem cell derived from

bone marrow and induced pluripotent stem cells

Matsuoka S

Osaka University Graduate School of Dentistry

BMP

1

C PKC

PKC

H 7 iso H 7

BMSC iPS

BMSC iPS H 7

iso H 7 6 WST 1

BMSC

H 7 iso H 7

28

RT PCR

Alizarin Red

iPS BMSC

28

RT PCR

Alizarin Red

WST 1 6

1 50 μM iso H 7 H 7

BMSC H 7 iso H 7

osteocalcin Runx2 osterix

P 0 01 H 7 iso H 7

BMSC

P 0 01 H 7 iso

H 7

m iPS H 7 iso

H 7

osteocalcin

Runx2 osterix P 0 01

H 7 iso H 7

P 0 01

H 7 iso H 7 BMSC

iPS

PKC

1 Egusa H, Saeki M, Fukuyasu S, Matsumoto T,

Kamisaki Y, Yatani H et al. A small-molecule

approach to bone regenerative medicine in

dentistry. J Oral Biosci 2010; 52:107-118.

BMSC iso-H-7, H-7

(Alizarin Red )

─ 154 ─


─ 154 ─

The effect of the heat treatment to the nanostructure of titanium on initial adhesion of rat bone marrow cells

Fujio M1), Komasa S1), Su Y1), Nishizaki M1), Sekino T2), Kusumoto T3), Nishizaki H1), Tanaka M3),

Okazaki J1)

1)department of removable prosthodontics and occlusion, osaka dental university, 2)isir-sanken, osaka

university, 3)department of fixed prosthodontics and occlision, osaka dental university

JIS2

TNS 2000

200 400 600 800

SEM SPM

XPS

XRD

7 SD

3 1

3 6 24 Cell

Titer Blue Assay Kit

1 3 6 24

Tukey

5

SEM SPM

200 400 600

Ra

200 400 600

13 0nm

800

Ra XPS

XRD

600 800

600

600

600

1 Su Y, Komasa S, Sekino T, Nishizaki H,

Okazaki J. Characterization and Bone

Differentiation of Nanoporous Structure

Fabricated on Ti6Al4V Alloy. J Nanomater.

600 TNS

─ 155 ─


─ 155 ─

Osteoblast behavior on controlled micro/nano structured titanium surface.

Iwata N1), Nozaki K2), Yamashita K3), Miura H1), Nagai A2)

1)Department of Fixed Prosthodontics, Graduate School of Medical and Dental Sciences, Tokyo Medical

and Dental University, 2)Department of Material Biofunctions, Institute of Biomaterials and

Bioengineering, Tokyo Medical and Dental University, 3)Department of Inorganic Biomaterials, Institute of

Biomaterials and Bioengineering, Tokyo Medical and Dental University

1

30 90

180μm 0

6MPa SB

0 5 wt NaF 1M Na2SO4 20V 3h

TNT

500oC 2h

SEM

S 3400NX X XRD D8

Advance Bruker

VK8500 Keyence

MG63

5x105 cells ml 1 3 7

MTT assay

1 4 7

ALP

SEM

10 70μm

100nm

TiO2

7 TNT SBTNT

ALP 7

SBTNT TNT

1 Zhang H et al. RSC Adv. 2015;5(48):

38117-38124

─ 156 ─


─ 156 ─

Influence of dental resin monomers on osteoclast differentiation

Inamitsu H, Takase K, Kurogi T, Murata H

Department of Prosthetic Dentistry,Graduate School of Biomedical Sciences,Nagasaki University

1 2

HEMA

TEGDMA

10 FBS

M CSF MEM 37 CO2 3

2 104cell ml RANKL HEMA

TEGDMA 0 0 1 0 2 0 5 1 0mM

37 CO2 3

cell count kit8®

TRAP

cell lysate

Western Blot

0 5mM

TRAP

0 2mM

Western Blot

HEMA TEGDMA

HEMA TEGDMA 0 5mM

1 Stephanie K,Karl-Anton H,Carola B,Christine

P,Gianrico S,Franz-Xaver R,Gottfried S,Helmut

S. Function of MAPK and downstream

transcription factors in monomer-induced

apoptosis. Biomaterials 2012:33:740-750

2 Emmler J,Seiss M, Kreppel H,Reichl FX,Hickel

R,Kehe K. Cytotoxicity of the dental composite

component TEGDMA and selected metabolic

by-products in human pulmonary cells. Dent

Mater 2008:1670-1675

.HEMA

─ 157 ─


─ 157 ─

Optimization of adsorption amount of polyphosphate to hydroxyapatite

Kato K, Morita K, Doi K, Kubo T, Abe Y, Tsuga K

Department of Advanced Prosthodontics, Applied Life Sciences, Institute of Biomedical & Health

Sciences, Hiroshima University

65 Poly P

1 2 Poly P

HA scaffold Poly P

HA

Poly P

Poly P

HA scaffold

HA Poly P Poly P

HA 10 mm 10 mm 2 mm 0 01–

10 mM Poly P 24

Poly P

SEM

HA 13 mm 2 mm 0 01–

10 mM Poly P 24

MC3T3

E1 0 1 3

7 10

MC3T3 E1

3 6 9 12 real time PCR

Alkaline phosphatase ALP Osteopontin

OPN Osteocalcin OCN mRNA

12 S

one way ANOVA

Tukey 5

Poly P HA

SEM Poly P

0

1 mM Poly P

Poly P 3 6 ALP

6 9 OPN 12 OCN

1 mM Poly P

0 01 mM Poly P

0 1 mM Poly P

0 01 mM Poly P

1 Tsutsumi K, Saito N, Kawazoe Y, Ooi HK,

Shiba T. Morphogenetic study on the maturation

of osteoblastic cell as induced by inorganic

polyphosphate. PloS One 2014; 9: e86834.

2 Hoac B, Kiffer-Moreira T, Millán JL, McKee

MD. Polyphosphates inhibit extracellular matrix

mineralization in MC3T3-E1 osteoblast cultures.

Bone 2013; 53: 478–486.

─ 158 ─


─ 158 ─

I

Type I collagen and hydroxyapatite composite controls periodontal ligament cell behavior

Fujita K1), Nozaki K2), Yamashita K3), Miura H1), Nagai A2)

1)Department of Fixed Prosthodontics, Graduate School of Medical and Dental Sciences, 2)Department of

Material Biofunctions, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University.,3)Department of Inorganic Biomaterials, Institute of Biomaterials and Bioengineering, Tokyo Medical and

Dental University.

HAp

HAp

HAp

ALP assay

Wistar Rat 6

HAp

Ca P 1 67

24 800

1250 HAp X

XRD FT IR

SEM

HAp Cellmatrix TypeI C

cellnest

0 1 Fujifilm corporation

HAp

5 x 104 ml

1 4 7

ALP assay ALP

LabAssay ALP Wako

XRD HAp

FT IR

3600cm 1

HAp HAp

SEM

ALP 4

cellnest Cellmatrix

cellnest HAp

TypeI RGD

cellnest

ALP

ALP TypeI

1 HA SEM

─ 159 ─


─ 159 ─

Human enamel wear against prosthetic materials: effect of their surface roughness and contact conditions

Tachibana K1), Kuwatsuru R1), Tsukiyama Y1), Atsuta I1), Morita T2), Kawakami Y3), Noma K3),

Matsushita Y1), Sawae Y2), Koyano K1)

1)Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, 2)Machine Elements and

Design Laboratory, Kyushu University, 3)Dental Laboratory, Kyushu University Hospital

3 Au

LD Zr

n 8

n 8

49N

2mm 1mm 2Hz

1

2

3 3

Au LD Zr

Zr

1 Au

LD

Au Zr

2 Au

3 Au

LD Zr

Au

Zr

LD Zr

1

Zr

1 Preis V et al., Wear performance of substructure

ceramics and veneering porcelains. Dental

mateirals: official publication of Academy of

Dental Materials. 2011; 27: 796-804

─ 160 ─


─ 160 ─

OSCC

Effect of magnetic field exposure on the expression of cytokines of OSCC

Obayashi M1), Omagari D2), Asano M2), Tsukimura N1), Ishii T1), Ishigami T1)

1)Department of Partial Denture Prosthodontics, Nihon University school of Dentistry, 2)Department of

Pathology, Nihon University school of Dentistry

1 2

Oral Squamous

Cell Carcinoma derived cell line OSCC 10

FCS RPMI1640 10 FCS MEM

37 5 CO2

Super Magnetic plate OZ Bioscience

control

TC20

Bio Rad 0 1 3 5 7

OSCC 2x105 24 well plate

12 control

Proteome Profiler Human XL

Cytokine Array Kit R D systems

RNeasy MINI

Kit QIAGEN RNA cDNA

real time PCR

control

Cytokine Array

Platelet

Derived Growth Factor AA PDGF AA ST2

control

PDGF AA ST2 real

time PCR

control 1 5

PDGF AA

ST2

IL 33 receptor

1 Vallbonaa C.Hazelwood CF,Jurida G. Response

of pain to static magnetic filds in postpolio

patient. A double-blind pilot study. A double-

blimd pilot study, Archives of Physucal and

Rehabilitative Medicine 78:1200-1203,1997

2 .

. :2008;17(1):12-23

Cytokine Array

─ 161 ─


─ 161 ─

Fabrication and evaluation of yttria-stabilized zirconia with antimicrobial properties

Yamada R1,2), Nozaki K2), Nemoto R1), Yamashita K3), Miura H1), Nagai A2)

1)Department of Fixed Prosthodontics, Graduate School of Medical and Dental Science, Tokyo Medical and

Dental University, 2)Department of Material Biofunctions, Institute of Biomaterials and Bioengineering,

Tokyo Medical and Dental University, 3)Department of Inorganic Biomaterials, Institute of Biomaterials

and Bioengineering, Tokyo Medical and Dental University

1

YSZ

YSZ

YSZ

YSZ TZ 3YSB E

1450 2

0 2

0 5 1 0 2 5 5 0 mM

SEM S 3400NX

X XRD D8 Advance

Bruker

NBRC

102135 MT8148

JIS Z 2801

37 24

37 24

SEM

YSZ

XRD

YSZ

1 Shin-Fu Ou Research of antibacterial activity

on silver containing yttria-stabilized-zirconia

bioceramic Ceram Int.2013;39:3591-3596

5.0mM YSZ

─ 162 ─


─ 162 ─

S PRG

Effect of S-PRG filler content on Candida biofilms adherence and physical properties of tissue conditioner

Takakusaki K1), Fueki K1), Tsutsumi C1), Takahashi H2), Hirasawa M1), Wakabayashi N1)

1)Removable Partial Prosthodontics, Graduate School, Tokyo Medical and Dental University (TMDU), 2)

Oral Biomaterials Engineering,Graduate School of Medical and Dental Sciences, Graduate School, Tokyo

Medical and Dental University (TMDU)

Tissue conditioner TC

Candida albicans

Surface reaction type pre

reacted glass ionomer S PRG

Polymethyl methacrylate PMMA C albicans1

S PRG TC

C albicans

S PRG 0 5 10 20

TC

TC

10 mm 2 mm

PMMA

24

YPD C albicans JCM2085

104cell ml 1 ml

37 C 16 Colony Forming

Unit CFU assay

n 16

n 4

n 5

Milli Q® 1 ml 24

ICP

n 5 LEXT

OLS4000 OLYMPUS

n 5

Dunnett P 0 05

CFU assay

0 10 20

P 0 05

P 0 05 10

P 0 05

P 0 05

TC S PRG

C albican10

1 Tsutsumi C, Takakuda K, Wakabayashi N.:

Reduction of Candida biofilm adhesion by

incorporation of prereacted glass ionomer filler

in denture base resin. J Dent.2016;44(1):37-43.

S-PRG CFU

─ 163 ─


─ 163 ─

4

Educational Effect of Palatal Augmentation Prosthesis for Dysphagia Treatment

-Part 4- Learning Through Experience about PAP for Dental School Student

Iida T1), Tsusumi I2), Isshiki Y1,2), Kanno K2), Tamaki K2)

1)Department of Critical Care Medicine and Dentistry, Division of Medically Compromised Geriatric

Dentistry Graduate School of Dentistry, Kanagawa Dental University, 2)Department of Oral Function and

Restoration, Division of Prosthodontic dentistry for function of TMJ and Occlusion, Graduate School of

Dentistry, Kanagawa Dental University

22

palatal augmentation prosthesis

PAP

PAP

PAP

1

PAP PAP

17 11 6

5mm

Mousepiece

as Impairment Simulatior for Lingual Action

MISLA PreM

MISLA

RSST MWST

FT

PAP

PAP PAP

PreM MISLA PAP

PAP

paired t test SPSS ver 22

0 IBM

PreM RSST 7 3 MWST 5 0 FT 4 9 MISLA

RSST 4 2 MWST 3 7 FT 2 2 PAP

RSST 5 1 MWST 4 4 FT 3 4

72 4 80 0

MISLA PAP

PAP 2

MISLA

PAP

PAP

1

. 2012;16

(1):32-41.

2

. 2011;15(3):274-83.

─ 164 ─

日補綴会誌　8・125回特別号，2016第 2日　第 3会場一般口演発表

─ 164 ─

Impacts of wearing complete dentures on the movement of mandible and hyoid during bolus formation.

Onodera S1), Furuya J2), Yamamoto H1), Sato T1), Hara A1), Aki S1), Matsuki K1), Tamada Y1), Kondo H1)

1)Department of Prosthodontics and Oral Implantology, School of Dentistry, Iwate Medical University, 2)

Department of Oral Health Care Science for Community and Welfare, Graduate School of Medical and

Dental Sciences, Tokyo Medical and Dental University

18 77 5 7 3

1

Dipp Motion V

Ditect

1

Wilcoxn signed rank test

5

No 01150

1

1

1 Yamamoto H Furuya J Tamada Y Kondo H

Impacts of wearing complete dentures on bolus

transport during feeding in elderly edentulous J

Oral Rehabil 2013; 40: 923-931

1 Me HYO

─ 165 ─

日補綴会誌　8・125回特別号，2016 第 2日　第 3会場一般口演発表

─ 165 ─

Elastic Modulus Estimation of the Denture Support Mucosa of Maxillary All Denture Wearing Patients

- Comparison of the Measured Value and Finite Element Analysis -

Takamatsu N, Sato Y, Kitagawa N, Shimodaira O, Shitita T, Isobe A, Kamisawa Y, Ogawa T, Tanaka S

Department of Geriatric Dentistry, Showa University School of Dentistry

1 2

2

17 8 9 78 4

3

3

10 10 mm

1

5

2

1 Isobe, A., Sato, Y., Kitagawa, N., et al. The

influence of denture supporting tissue properties

on pressure-pain threshold:–Measurement in

dentate subjects– J. Prosthodont. Res, 2013; 57:

275-283.

2 Kotani, Y., Sato, Y., Kitagawa, N., et al.

Relationship between palatal mucosa properties

and pressure-pain threshold in young dentulous

and elderly edentulous subjects J J Gerodont,

2015; 30: 68-79.

1

2

─ 166 ─


─ 166 ─

The Effect of Residual Ridge Form and Denture Form on the Retention Force of Mandibular Complete

Dentures.

Ishihara M, Sato Y, Kitagawa N, Nakatsu M, Aoyagi K, Kakuda T, Takayama M, Tsubakida K


1

37

14 23 83

®

45

1 cm 2 cm 3 cm 4

20 N

2

ST

A B

Shapiro Wilk

Wilcoxon Kruskal Wallis

Spearman

2015 005

p 0

05 1 cm

p 0 05 A

r 0 733 p 0 01

A B

r 0 608 p 0 01 1

1 cm

1 Kakuda T, Sato Y, Kitagawa N., et al.

Examination of optimal sites and loading

methods for measuring maxillary complete

denture retention. J J Gerodont. 2015; 30: 25-36.

1

─ 167 ─


─ 167 ─

The influences of relief on supporting ability of palatal plates in dentate.

Tanaka S, Sato Y, Kitagawa N, Shimodaira O, Isobe A, Kamisawa Y, Takamatsu N, Iijima H


1

2 3

15 8 7

28 9

0 23 10 1

0 46 10 2

3

5 3

1

0 23 0

46

P 0

05 0 23 0 46

1

2010; 2: 70-77.

2 Isobe A, Sato Y, Kitagawa N et al. The influence

of denture supporting tissue properties on

pressure-pain threshold: -Measurement in

dentate subjects- J Prosthodont Res 2013; 57:

275-283.

3 Kotani Y, Sato Y, Kitagawa N et al.

Relationship between palatal mucosa properties

and pressure-pain threshold in young dentulous

and elderly edentulous subjects. J J Gerodont

2015; 30: 68-79.

1

─ 168 ─


─ 168 ─

RPD

The change of alveolar bone surrounding abutment teeth with removable partial denture placement in

patients of periodontitis

A digital subtraction analysis

Watanabe C1), Wada J1), Mizutani K2), Watanabe H3), Wakabayashi N1)

1)Department of Removable Prosthodontics, Oral Health Sciences, Graduate School of Dentistry, Tokyo

Medical and Dental University, 2)Department of Periodontology, Tokyo Medical and Dental University, 3)

Department of Oral Radiology, Tokyo Medical and Dental University

Removable Partial Denture RPD

1

RPD

RPD

11 5 6

RPD 16

RPD

1

1 1 3

GC

Emago Oral Diagnotic System

Region of Interest ROI

6

0 255

127

ROI

1105

RPD

123 140

RPD 3

1 Carneiro LS, da Cunha HA, Leles CR,

Mendonça EF. Digital subtraction radiography

evaluation of longitudinal bone density changes

around immediate loading implants: a pilot study.

Dentomaxillofac Radiol. 2012;41(3):241-7

─ 169 ─


─ 169 ─

How to educate the advantages of mesial rests for free-end missing

Sato Y, Kitagawa N


29

24

13

7

RPI

4

4

1963 Kratochvil1

A

4 1 2

4

1 Kratochvil FJ Influence of occlusal rest

position and clasp design on movement of

abutment teeth. J Prosthet Dent 1963; 13:

114-124.

─ 170 ─


─ 170 ─

Accuracy of morphological measurement using oral scanner for edentulous jaw and free-end partially

edentulous region

Tasaka A1,5), Mitsui T1,5), Kasahara T1), Uekubo Y1), Takanashi T2), Homma S2), Matsunaga S3,5), Abe S3),

Sakurai K4), Yamashita S1)

1)Department of Removable Partial Prosthodontics, Tokyo Dental College, 2)Department of Oral and

Maxillofacial Implantology, Tokyo Dental College, 3)Department of Anatomy, Tokyo Dental College, 4)

Department of Removable Prosthodontics and Gerodontology, Tokyo Dental College, 5)Oral Health

Science Center, Tokyo Dental College

3D

1

2 3

G10FE 402K P25 TP49

D900 3Shape

3D

TRIOS 3Shape

CAD Dental System 3Shape

2

5 5

Kruskal

Wallis 0 05

0 30 0

24mm 0 18 0 04mm 0 18 0

07mm 4 17 2 30mm2

6 82 2 48mm2 4 70 2 30mm2

0 05 0

01mm 0 08 0 05mm

0 78 0 21mm2 1 60 0 71mm2

0 7 1 0mm

1 Brawek PK, Wolfart S, Endres L, Kirsten A,

Reich S. The clinical accuracy of single crowns

exclusively fabricated by digital workflow-the

comparison of two systems. Clin Oral Investig.

2013; 17: 2119-2125.

2 Ender A, Mehn A. Accuracy of complete-arch

dental impressions: a new method of measuring

trueness and precision. J Prosthet Dent. 2013;

109: 121-128.

3 Patzelt SB, Emmanouilidi A, Stampf S, Strub JR,

Att W. Accuracy of full-arch scans using

intraoral scanners. Clin Oral Investig. 2014; 18:

1687-1694.

─ 171 ─


─ 171 ─

Clasp fabrication using the one process molding by repeated laser sintering and high-speed milling.

Nakata T, Shimpo H, Urushibara Y, Ohkubo C

Dept. of Removable Prosthodontics, Tsurumi University School of Dental Medicine

CAD CAM

2

1

2

LUMEX

Avance 25

3

X

0 5 mm 12 0

mm 3

10 000

50 mm min

Tukey

5

0 8 m

16 3N

12 9N 3

11 3N

1 Shimpo H. Effect of arm design and chemical

polishing on retentive force of cast titanium

alloy clasps. J Prosthodont. 2008; 17: 300-7.

2 Diego M, Flaviana C, Manickavasagam K, et al.

From powders to dense metal parts:

Characterization of a commercial AlSiMg alloy

processed through direct metal laser sintering.

Materials 2013; 6: 856-69.

─ 172 ─


─ 172 ─

CAD CAM

Fully digital fabrication of removable partial denture using CAD/CAM

Ozawa D, Takagi I, Kurihara D, Suzuki G, Ohkubo C

Department of Removable Prosthodontics, Tsurumi University School of Dental Medicine

70

CAD CAM

CAD CAM

CAD CAM

ARCTICA Scan KaVo

CAD

multi CAD KaVo

EVEREST KaVo

CAD

DWOS PFW Dental Wings

2

2

ENAMIC VITA

1 Kanazawa M, Inokoshi M, Minakuchi S,

Ohbayashi N.Trialof a CAD/CAM system for

fabricating completedentures.DentMaterJ2011;

30:93 96.

2 InokoshiM,KanazawaM,MinakuchiS.Evaluation

of

acompletedenturetrialmethodapplyingrapidprotot

yping.DentMaterJ2012;31:40 46.

─ 173 ─


─ 173 ─

QOL

Determining Minimally Important Difference for Oral Health-related Quality of Life in Patients with Fixed

or Removable Partial Denture.

Nakagawa S1), Kimura-ono A2), Kurosaki Y1), Koyama E1), Osaka S1), Numoto K1), Mino T1),

Minakuchi H1), Maekawa K1), Kuboki T1)

1)Department of Oral Rehabilitation and Regenerative Medicine, Okayama University Graduate School of

Medicine, Dentistry and Pharmaceutical Sciences, 2)Center for Innovative Clinical Medicine Okayama

University Hospital

Quality of life QOL

QOL

QOL

QOL

QOL

QOL 1 BR

PD

2013 11 2015 8

8 BR PD

629

154 63 1 11 8

60 94 BR PD 81 73

QOL

Oral Health Impact Profile

QOL

Patient Global Impression of

Improvement2

7

3

QOL Anchor

based method3

BR 76

1 4 0 6 PD 68 3 5 1 9

QOL BR

49 3 12 1 54 4 9 6

p 0 005 PD

44 0 15 6 50 0 13 1

p 0 018

BR

1 11 64

QOL 16 0

9 2 4 8 9 2

PD

2 9 57 QOL

20 2 3 7 5

2 3

QOL

QOL

1

QOL

1999 43(4) 698 705

2 Yalchin L Bump R. Validation of two global

impression questionnaires for incontinence. Am

J Obstet Gynecol. 2003 : 189(1) : 98-101.

3 Juniper E, Guyatt G, Willan A et al. Determining

a minimal important change in a disease-specific

quality of life questionnaire. J Clin Epidemiol.

1994 : 47(1) : 81-87.

─ 174 ─


─ 174 ─

Candida albicans

The difference of antifungal ability of Candida albicans adhere to different denture form

Fujishima K, Murakami M, Suehiro F, Nishi Y, Nishimura M

Department of Oral and Maxillofacial Prosthodontics Graduate School of Medical and Dental Sciences

Kagoshima University

1

Candida albicans C albicans

pH

C albicansC albicans

C albicans

C albicans C albicans

16 26

CHROMagar

26 122

C albicansPCR C albicans

1 MIC

amphotericinB 2

C albicansJCM1537

16 5 26

5 C albicans C albicans31 3 19 2 JCM1537

amphotericinB

MIC 0 125 0 0625 0 125 0

125 0 25

54 9

67 1

Calbicans

1 Jeniel E. Nett, Karen Marchillo, et. al.

Development and Validation of an In Vivo

Candida albicans Biofilm Denture Model. Infect

Immun. 2010, p3650-3659

─ 175 ─


─ 175 ─

Clinical analysis on relationship between medication related osteonecrosis of the jaw (MRONJ) and

removable denture.

Kaiju N1), Ouchi T1), Usuda S1), Niibe K1,2), Iwasaki R1), Morikawa S1), Arima N1), Nishiyama R1),

Suzuki K1), Suzuki K1), Nakagawa T1), Horie N1)

1)Department of Dentistry and Oral Surgery, Keio University School of Medicine, 2)Division of Molecular

and Regenerative Prosthodontics, Tohoku University Graduate School of Dentistry

BP

BP

Medication Related

Osteonecrosis of the Jaw MRONJ

MRONJ

MRONJ

2015 1 12 1

BP

344

MRONJ 17

128

216 113

231

MRONJ 10

7 MRONJ

1 15 1

60 70

MRONJ

MRONJ

MRONJ

MRONJ

MRONJ

1 Niibe K, Ouchi T, Iwasaki R et al. Osteonecrosis

of the jaw in patients with dental prostheses

being treated with bisphosphonates or

denosumab. Journal of Prosthodontic Research

2015 ; 59 : 3–5.

2

. 26

18

2014 ; 28.

3

10

. 2015; 7 124

: 296.

4 2014; 6 3 : 233-241

MRONJ

─ 176 ─


─ 176 ─

Influence of mandibular distal extension removable partial denture wearing on force applied on maxillary

anterior teeth.

Arita S, Gonda T, Maeda Y

Department of Prosthodontics, Gerodontology and Oral Rehabilitation, Osaka University Graduate School

of Dentistry.

1

2

D51FE 500A QF

4567

2mm

RPD

4mm

8mm

4mm

RPD

IRPD

IRPD

RPD IRPD 3

49N

6

2

Kruskal Wallis

Bonferroni

P 0 05

RPD

IRPD

P 0 05

1

2013;5(1):21-27.

2 5

2012; 4(2): 178-182.

─ 177 ─


─ 177 ─

A case report. Treatment of implant-supported non metal clasp removable partial overdenture.

Shinozaki Y1), Yamaguchi Y1), Matsuura T1), Kido H2), Sato H1)

1)Department of Oral Rehabilitation, Section of Fixed Prosthodontics, Fukuoka Dental College, 2)

Department of Oral Rehabilitation, Section of Oral Implantology, Fukuoka Dental College

GBR

GBR

1

Implant supported removable partial

denture

64

22 5 10

22 5

22 11 CT

GBR

GBR

23 1 4 0mm 7mm 1

4 2 23 10

26 10

4

4

5

1 Advanced Removable Partial Dentures 1999

James S. Brudvik .

─ 178 ─


─ 178 ─

Mechanical effects of the shape of alveolar ridges and occlusal contacts on supporting tissue of implant

overdentures

Uchiyama S, Takayama Y, Yokoyama A

Department of Oral Functional Prosthodontics, Division of Oral Functional Science, Graduate School of

Dental Medicine, Hokkaido University

IOD

IOD

IOD

IOD

2

IOD

N N

A 2

1 2

0 02 0 4

CO

LO1 LO

LO B

LO U

LO C 3 N

IOD 130N

A N

20 50

Frost

3000

microstrain 2 LO U

N A

3000 microstrain

LO U LO C LO B

LO U LO B

LO C LO C LO

U LO B

LO B

LO C LO U

1 Korioth TWP Hannam AG Deformation of the

Human Mandible During Simulated Tooth

Clenching J Dent Res 1994 73 56-66

2 Frost HM Bone's mechanostat A 2003

update Anat Rec A Discov Mol Cell Evol Biol

2003 275 1081-1101

1 2

─ 179 ─


─ 179 ─

1

2

Observation of abutment screw loosening at clinical practice.

Assessment at one week after implant-supported crown setting –

Katsuta Y1), Shinohara R1), Ozawa M1), Ueda K2), Watanabe F1)

1)Department of Crown and Bridge Prosthdontics, The Nippon Dental Univ. School of Life Dentistry at

Niigata, 2)Oral Implant Care Unit, The Nippon Dental Univ.Niigata Hospital

1

1

6 14

CAMLOG K series Straumann Tissue level

Bone level Dentsply Osseo speed 3

newton 1 newton 1

KTC

1

newton 1

1

1

49 5 31 2

14 1

1

1

2

Quintessence Dent Imp

2013 20(2) 124-132

1

─ 180 ─


─ 180 ─

3

Mechanical analysis of implant fixed dentures in mandibular free-end defect model

Yasuda H, Ohyama T, Nakabayashi S, Tadokoro S, Shibuya N, Ishii T, Obayashi M, Saito S, Ishigami T

Department of Partial Denture Prosthodontics, Nihon University School of Dentistry

3

3

3

3 A

2

B

2

C

2

D

4

A

B D

A C

D

A

B C

A

C

D

3 3

2

1 Rangert BR Sullivan RM Jemt TM Load

factor control for implants in the posterior

partially edentulous segment Int J Oral

Maxillofac Implants 1997 12 360-370

2 Korioth TW Hannam AG Deformation of the

human mandible during simulated tooth

clenching J Dent Res 1994 73 56-66

─ 181 ─


─ 181 ─

Shurenkai

Examination of occlusal force and occlusal contact area with implant superstructure having occlusal

vertical dimension variableness mechanism

Yamamoto M1), Nakamura K1), Arii K1), Okamoto N1), Mitsumoto K1), Takada T1), Nishihara H1),

Fukuzawa H1), Mizoi Y1), Onozawa H2)

1)Shurenkai, 2)GC Co.

1

50

1 1 2

0 m

1 2

200 m 50 m

200 m 150 m 100 m 50 m

0 m 50 m 100 m 150 m 200 m

9

DePROS

50H R L

1

709

1

BE 1

1 1

200 m 0 m

50 m 200 m

0 m

50 50

2 2

3

2

1

2016

8 1-9

─ 182 ─


─ 182 ─

Application of Oral Implants to Tooth Splinting

- Finite Element Analysis on the Differences among the Splinted Teeth -

Shibahara E1), Yamamori T1), Sekine T1), Ito J1), Sato K1), Nagata Y1), Takayama H1), Murashima N1),

Nonaka K1), Sekino T1), Takahashi K2), Waguri N2)

1)Department of Prosthetic Dentistry, Ohu University School of Dentistry, 2)Tokyo Branch

1

2

3

6

2 A

A 6

B A B

5 5mm C

D D

POM E

Gap

5kgf

1

2 A C B

D

C D E

1 Ericsson I. Lekholm U, Brånemark PI et al. A

clinical evaluation of fixed-bridge restorations

supported by the combination of teeth and

osseointegrated titanium implants. J Clin

Periodontol. 1986; 13: 307-312.

2 Cordaro L, Ercoli C, Rossini C et al.

Retrospective evaluation of complete-arch fixed

partial dentures connecting teeth and implant

abutments in patients with normal and reduced

periodontal support. J Prosthet Dent. 2005; 94:

313-320.

3

2015 28 242

1

2

─ 183 ─


─ 183 ─

Evaluation of accuracy and reproducibility of intraoral scanners

Fukazawa S, Odaira C, Ajioka H, Kihara H, Kobayashi T, Kondo H

Department of Prosthodontics and Oral Implantology, School of Dentistry Iwate Medical University

Information technology IT

CAD CAM

A

B C

D 6

4

10

3

3M™ True Definition

Scanner 3M™ True Definition Scanner

3shape TRIOS

KaVo ARCTICA Auto Scan

10

A B A C A D B C B

D C D

1 Mehl A, Ender A, Mormann W, Attin T.

Accuracy testing of a new intraoral 3D camera.

Int J Comput Dent2009; 12:11-28.

─ 184 ─


─ 184 ─

Digital Implant Treatment and Prosthodontic Planning Concept

Clinical Aspects

Ochiai K, Yamashita T

USC School of Dentistry

INTRODUCTION AND PURPOSE

The fundamental components of occlusal design are

important determinates of diagnosis for

reconstructive dentistry While the importance of

esthetic evaluation cannot be understated an

evidence based understanding of the relationships

between esthetic evaluation and the assessment of

functional landmarks are important concepts of

treatment design The focus of this presentation will

review the areas of diagnosis and occlusal evaluation

with digital restorative dental implant design and the

importance of these relationships to conventional

prosthetic treatment

The purpose of this presentation is to provide a

review of prosthodontic treatment planning concepts

and their significance to digital implant treatment

planning and the delivery of care

METHODS

Clinical case reports following patient treatment with

CAD CAM technology restorative design and

treatment procedures

RESULTS AND CONCLUSION

Although dental implants have been a ubiquitous

treatment methodology for providing dental support

in the partially and fully edentulous treatment

situations various patient physical factors will

always require understanding and consideration of

important prosthodontic diagnostic concepts and

relationships used with conventional prosthodontics

Digital design technology helps to better visualize

and understand these concepts and most importantly

provides the technical benefits of improved fit

function and economic benefit

Digital technology has facilitated the use of a

systematic approach to treatment planning and the

importance of restorative prescription Pre and

intra treatment prosthodontic evaluations assists in

determining the best course of treatment for desired

patient outcomes

─ 185 ─


─ 185 ─

Effect of dietary supplement on peri-implant bone micro architecture in a rat model osteoporosis

Watanabe T1), Takahashi T2), Satou H2), Tanimoto Y3), Nakada H1), Kimoto S1), Kitamura A1), Sato K2),

Iijima M1), Kawai Y1)

1)Department of Removable Prosthodontics, Nihon University of Dentistry at Matsudo, 2)Nihon University

Graduate School of Dentistry at Matsudo, Removable Prosthodontics, Matsudo, 3)Department of Dental

Biomaterials, Nihon University of Dentistry at Matsudo

1000

QOL

Synthetic bone mineral SBM1

SBM

SBM LeGeros RZ2 CaHPO4

2H2O MgCl2 ZnCl2 NaF K2CO3

AIN 93M

AIN 93M SBM

7

n 18 n 18

9

2 4

CT

Bone Surface Bone

Volume BS BV Bone Volume Tissue

Volume BV TV Trabecular Thickness

TbTh Trabecular Number TbN

Trabecular Star Volume Vtr

2 Mann–Whitney U

5

BS BV BV TV TbTh TbN

Vtr BV TV BS BV

TbTh

BV TV BS BV

TbTh

Vtr

TbN

SBM

SBM

SBM

1 Mijares D, Kulkarni A, Lewis K, Yao F, Xi Q,

Tannous S, et al. Oral bone loss induced by

mineral deficiency in a rat model: effect of a

synthetic bone mineral (SBM) preparation.

Archives of oral biology 2012;57:1264-73.

2 LeGeros RZ. Patent. 2008: US 7, B2 (submitted

2004,, issued September 2 UAC, March, 12 Cp-

bb, incorporating magnesium z, fluoride and

carbonate. ed., p. of.

─ 186 ─


─ 186 ─

The application of kaempferol on the titanium surface to facilitate osseointegration

Sugimoto K2), Tsuchiya S1), Hara K1), Fujio M2), Matsushita Y1), Matsuda R2), Sayo A2), Hibi H2)

1)Department of Oral and Maxillo facial Surgery, Nagoya University Hospital, 2)Department of Oral and

Maxillofacial Surgery, Nagoya University Graduate School of Medicine

1M 140 6

PBS 37 24 JIS1

80mm Ti P

2mm 4 5mm Ti S

Ti P Alk Ti S Alk

PBS 5μM

Ti P Alk Ka Ti S Alk Ka

5μM PBS 37 24

Ti P Alk Kc Ti S Alk

Kc

Ti P Ti S

SEM X

EDX

Ti P Ti P Alk Ti P Alk Ka Ti P Alk

Kc

rBMSCs 1

3 7 Runx 2 Osteocalcin

Osteopontin Osteonectin Type 1 Collagen Alkaline

Phosphatase mRNA RT PCR

SD 24 6 Ti S

Ti S Alk Ti S Alk Ka Ti S Alk Kc

2 4

BIC

SEM Ti P Alk Ka Ti P Alk Kc

Ti P Ti S Alk Ka Ti S Alk Kc

Ti S

EDX Ti P Alk Ka Ti P

Ti S Alk Ka Ti S

RT PCR Ti P Alk Ka

Ti P Alk Kc Ti P 7

Runx 2 Osteocalcin 2

4 BIC Ti S Alk Ka Ti S Alk Kc

Ti S Ti S Alk

Ti S Alk Ka Ti S Alk Kc

1 Yang L et al. Kaempferol stimulates bone

sialoprotein gene transcription and new bone

formation. J Cell Biochem. 2010; 110(6):1342-55

2 Kumar A et al. Identification of kaempferol-

regulated proteins in rat calvarial osteoblasts

during mineralization by proteomics. Proteomics.

2010;10(9):1730-9

─ 187 ─


─ 187 ─

MDF

Biological evaluation of MDF pure titanium as implant material

Arai Y1), Hoshi N1), Kumasaka T1), Maruo K1), Kuwabara A1), Ohkubo C2), Kimoto K1)

1)Division of Prosthodontics & Oral Rehabilitation Department of oral Function and Restoration Graduate

School of Dentistry, Kanagawa Dental University, 2)Department of Removable Prosthodontics, Tsurumi

University School of Dental Medicine

MDF

MDF

Grade 2

MDF

MDF 2 20 mm 1 0 mm

67 H SO 120

75

40 50 60 75

MDF

JEOL JSM 5600LV 15

kV

8 SD

MEM 15 fetal bovine serum

50 g ml ascorbic acid 10 mM Na

glycerophosphate 10 8 M dexamethasone

antibiotic antimycotic

37 5 CO2

2 3 80 0 25

trypsin 1 mM EDTA 4Na

12 well

MDF 6 2

10 4 cells cm2

3

WST 1 1 96 well

100 l 450nm

Turkey

5

MDF SEM

MDF 1 1

MDF

MDF

MDF

MDF

MDF

1 Sabirov, R. Z. Valiev, I. P. Semenova, R. Pippan.

Effect of equal channel angular pressing on the

fracture behavior of commercially pure titanium.

Matellurgical and Materials Transactions A010;

41(3): 727-733.

─ 188 ─


─ 188 ─

Evaluation of bone and soft tissue gain in maxillary anterior implants with graft surgery

Fujita Y, Nakano T, Kaminaka A, Kato T, Matsumura A, Yatani H

Department of Fixed Prosthodontics, Osaka University Graduate School of Dentistry

1

Cone Beam CT CBCT

CBCT

2012 2 2015 2

28 T0

T1 CBCT

coDiagnostiX Dental Wings T0

T1

T0 T1

BW0 GW0 2 mm

BW2 GW2

BA

BSA 3

T0 T1

0 05

H23 E8

n 7 BW0 BW2

BW0 0 4 0 3 mm BW2 0 5 0 4

mm BA n 14 BW0 BW2

BW0 1 0 0 7 mm BW2 1 1

0 7 mm BSA n 7

BW0 1 7 0 9 mm BW2

2 0 1 1 mm GW0 1 4 1 0 mm GW2

1 3 0 5 mm BA

T0 T1 GW0 GW2

1

T2 CBCT

1 Grunder U, Gracis S, Capelli M:Influence of the

3-D bone-to-implant relationship on esthetics.Int

J Periodontics Restorative Dent. 2005 Apr;25(2):

113-9.

T0 T1

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