2 () . , . ( ) , . DNA MRNA - DNA ( ) () , ATP - .1 .2 , ' " ' . "" .

. " DNA . DNA M-RNA" " . - () . -. " ATP . " .

. CNS . .

() . . ( ) " . . " , ATP . '. " ( ) (" ' ) . - CNS , 80 20 . ' 50 " . - () "" ( ). - PNS . PNS " ( ) ' "

- CNS " 50 *

: , ' .

- . . . , .

MV 70- .

- " () ATP ( ). . , . , ( . )

( 70 )40+ 75-

'

. . () 55- 40+ .

40+ " 70- . - ( ) 40+ - .1 .2 .3 .4 .5 .6

40+

" " " .

.

: - , , . " - " " " " "

" ( ) " . " - " " " " " . " , .

" "

PSP EPSP IPSP PSP . PSP , . EPSP , IPSP " " " , EPSP EPSP - . EPSP , .

, . - - - " " . . : - . " ' " ( ) . " " . - " " . .

: " " .

( : ) " " " . " . . - . - "

. " G AMP ATP .

-. . .1 -" " .2- - " . " . ACHE 500 ACH .

?, ? : ) .

? - - - - " " . - . " .

3

. CSF . . . - . - . .CSF CNS . 80 . . CSF , " . ( ).

: . . ( . ) . . . () . ( . ) " " ( ) .

: . . . ' ( "" ) - - . ( ) ( ): - " . - - - . - , () , - , . - .

: - . . - . . - ( ) . . - .

: - . . - . . : .

. . , . .

.

, . , , .

: , . . fight or flight ' . , , . . . - . .

' . .

-

rest and digest . . : . , .

fight and flight . , . : .

?

- - - -

.

4 () . = . = . ( ) . ( ) . . . .

, . . . "" . .

? ? . ( ) . , . , . = .

? ? ? = , . . . "

. : .1 ( ) .2 . "

()? \ . '

: , . , , . 2 , . : ' ' . ' ' ' . ( ) . ' .

' , ' ' , ' - ' . . .

. . . COA A . ChAT COA COA . - ' " " " " .

\ - - - . - 5 .

"? . - . - , , . . REM . .

. - () . - - . - - . , , - . . . LSD

MAO-A MAO- :

B ACHE'

- ACHE . " reaptake " MAO MAO ' , . PCPA .

6 ? ? . , . , , .

: . . . . . , . , , . , . - , . , () . ( ) .

: . . . ( . ) .

- \ . . .

( )

- ( .

. ? ? ( ) () . " GMP . ,30- ( ) () . ( ) . G , GDP GTP- ( ) G - GMP . .70- .

? ( ) . (. ' )215 ( )

( ) . : .1 . ' . . .2 , .3 (. )

. . . ( ) .

. . - . \ .

? ! .

. -. ,

. . 25 - . 2500 ( ) .

, . , . - . . . . - ( .

- . . - , . ( ) .

. . 2500 ,

. CO .

. . .

. "" "" . : , . ( ) . .

. V4 8V ' "" . '. - . , , , . . " , , " . .

FFA . ERB PPA FFA , ... "". EBA PPA .

. . " . - . . .