Function and structure of bioomembranes

biomembranes A B C D E F

15%-20%(lipid)1234

1216183 Glycerophospholipids

Glycosphingolipids

2030%

peripheral protein

integral protein 70-80%

---

simple diffusion) facilitated diffusion1)23

active transport123-

Na+-K+ ATPase Na-K Na-K-ATP22Na-K-ATP

Na+,K+; K+,Na+

phagocytosis

DNA

ligand

I

G-

: DNA

GG GTPGTPGDP GDPGTP

G7-

cAMP-PKA cAMPAprotein kinase A,PKA

1 2 ()A(PKA)

GTP/GDPG

AC

cAMP

PKA

C(protein kinase CPKC) (diglycerideDG)C (DG) GCC(PIP2)(IP3)DG

DGPKCPKC(DNANaKATP)

()IP3-Ca++/CaM IP3Ca2+

IP3Ca2+ Ca2+ Ca2+ Ca2+(CaM)CaM Ca2+Mg2+ATP

IP3

-

DNA DNA

DNA