急性肾损伤 acute kidney injury (aki)
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急性肾损伤 Acute Kidney Injury (AKI). 浙江大学邵逸夫医院肾脏科 叶有新. 浙江大学附属邵逸夫医院肾脏科 叶有新. 肾 脏 解 剖 Anatomy of the Kidney. 正常肾脏功能 Renal function. 排除毒素 Excretion of toxin 维持机体水、电解质和酸碱平衡 Maintaining water,electrolytes and acid-base balance 内分泌 Endocrine. AKI 分类. pre. intra. post. - PowerPoint PPT PresentationTRANSCRIPT
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Acute Kidney Injury (AKI)
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Anatomy of the Kidney
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Renal function Excretion of toxin Maintaining water,electrolytes and acid-base balance Endocrine
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AKI prepostintra
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ARF)DEFINITIONAKI represents an abrupt decrease in the ability of the kidney to excrete nitrogenous wastes,resulting in azotemia, fluid retaintion, electrolyte disturbance and metabolic acidosis.
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AKI 480.3mg/dl150%0.5ml/kg/h61 Scr 0.3mg/dl 150% U V 0.5ml/kg/h 6h2 Scr 200%-300% U V 0.5ml/kg/h 12h3 Scr 300% 4mg 0.5mg U V 0.3ml/kg/h 24h anv12h
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PrerenalKIAKI55%Renal hypoperfusion is responsible for 55% of the AKI.
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Etiology
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Symptoms and signsThirst , Dry skin and mucoseWeight loss . Orthostatic hypotension Tachcardia , Flat neck vein Oliguria
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Laboratory Tests
Hemoconcentration>1.030, Urine specific gravity>1.030>500mosm/kgH2O, Urine osmolality >500mOsm/kgH2O 20 ,FENa80mg/dl> 5.9mg K+>5.9mEq/L pH