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  • :2012.NICE154guidance.nice.org.uk/cg154

  • 1

    ................................................................................................2

    ............................................................................................................3

    ........................................................................................................4.........................................................................................................................4...............................................................................4.....................................................4..........................................................................................5

    .....................................................................................................................................................5.....................................................................................................................................................5...............................................................................................................................................................5........................................................................................................................................5...........................................................................................................................5

    1.............................................................................................................................................................6..........................................................................................................................61.2......................................................................71.3 ...............................................71.4

    .........................................................................................................................................................................91.5..........................................................................................................................131.6 ...................................................................................................................151.7AntiDrhesus.......................................................................................................................................17

    2...........................................................................................................................182.1 ..............................................................................................182.2 ...............................................182.3 Progesterone/progestogen.................................................................................192.4..................................................................................................................202.5 ,..........................20

    3............................................................................................................................................213.1..............................................................................................213.2NICE..........................................................................................................................................21

    4.,NICE.................................................................................................................................................234.1..............................................................................................................................234.2.....................................................234.3NICE.....................................................................................................................................................23

    .....................................................................................................................................24....................................................................................................................................................24........................................................................................................................................25..................................................................................................................................................................25.........................................................................................................................................................25....................................................................................................................................................................25NICE...................................................................................................................................................................25

  • NICE154

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  • NICE154

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  • NICE154

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  • NICE154

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  • NICE154

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  • NICE154

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  • NICE154

    16

    , .

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  • NICE154

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  • NICE154

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  • NICE154

    19

    , , . ,, . ()5,1014.,, . , 14 . ,, 14 , 7 .2.3 Progesterone/progestogen progesterone progestogen ?20%,/. , / progesterone progestogen . , progestogen . , .. , progesterone/ progestogen. ,. , , , , 612.Progesterone/progestogenplacebo , 13 . .,, , .

  • NICE154

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  • NICE154

    21

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  • NICE154

    22

    .NICE107(2010). . NICE 92(2010).

    .NICE74(2008). .NICE63(2008). .NICE62(2008). antiD rhesus D . NICE156(2008).

    . NICE 45 (2007)..NICE11(2004).

    NICE(NICE): (update). NICE . .

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  • NICE154

    23

    4.,NICE

    4.1(11,guidance.nice.org.uk/cg154)4.2(9,guidance.nice.org.uk/cg154)

    4.3NICE(6,guidance.nice.org.uk/cg154)

  • NICE154

    24

    NICENHS.NICE,. National Collaborating Centre for Women's andChildren's Health, Royal College of Obstetricians andGynaecologists., ( , ,),,,.. NICE .. ,. , , , . , , , (). , NICE . (,).()''''. '' ( ' ') .()''''(''''),, . (,'...'). '',

  • NICE154

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    . ,,.,': ' . NationalCollaboratingCentreforWomen'sandChildren'sHealth. NICE Pathway. .. NICE, .., , , ,/,. / ( ). , , ,.. National Institute for Health and Clinical Excellence 2012. . NICE ,. NICE, .NICENationalInstituteforHealthandClinicalExcellenceLevel1A,CityTower,PiccadillyPlaza,ManchesterM14BT