二 平 成 年 度 十 九 年 度 授 業 内 容 · bioorganic cheistry on 1） determination of...
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Food & Agricultural Immunology Joint Lecture 5 53
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36 Immunology Lecture 82
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Bioorganic cheistry on 1 determination of relative/absolute streochemistry of natural products and 2 investigation on mode of action of natural products
Object This course offers an opportunity to learn importane of isolation, structure determination and total synthesis in research studies of natural product chemistry and to help students develop knowledge on chemical biology where mode of action of natural products are investigated with designed and synthesized chemical probes.
Summary of Class First, researhers who study different fields of natural product chemistry introduce methods for
determining stereochemisty of natural products and purification of optically pure compounds. Students will then learn how to synthesize chemical probes and how to evaluate mode of action of natural products.
Stereochemistry, total synthesis, structure determination, biological activity, chemical biology
Students will understand basics on stereochemistry of organic compounds and learn various techniques to determine streochemistry of organic compounds.
Relative/absolute stereochemistry of organic compounds and optical purity Masaru Enomoto Methods for determination of relative/absolute streochemistry of organic compounds and for optical
purity Synthesis of optically pure organic compounds using asymmetric metal catalysts Masaru Enomoto Synthesis of optically pure organic compounds using asymmetric organic molecular catalysts Masaru
Enomoto Synthesis of optically pure organic compounds using enzymes purified from yeasts Masaru Enomoto Retrosynthesis of natural products Shigefumi Kuwahara Reseearch studies of natural products Shigefumi Kuwahara Measurements of biological activities of natural products Keiichi Konoki Heterologous expression of recombinant proteins and measurement of their biological activities Keiichi
Konoki Photoaffinity labeling of binding proteins for natural products Keiichi Konoki
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Affinity chromatography for identifying binding proteins for natural products Keiichi Konoki Natural products exhibiting their biological activities against voltage-gated ion channels Mari Yotsu-
Yamashita S creening of drug candidates using chemical library Keiichi Konoki NMR Application of NMR to the study of natural products Mari Yotsu-Yamashita Structure determination of natural products Mari Yotsu-Yamashita End of term exam
Impact Factor 5 Full Paper 5 Evaluation if performed comprehensively based on submitted reports and end-of-term exam. Students are required to submit a report in which they read a recent full paper with impact factor more than 5.0 and summarize and print out using more than 5 pages of A4-size papers. The theme of the paper should be either "determination of optical purifity or relative/absolute streochemistry of organic compunds" or "chemical biology"
Students are recommended to review what they learned about organic chemistry by reading the folloiwng references.
Reference I/II/III Reference / : Organic Chemistry Jonathan Clayden,
Nick Greeves, and Stuart Warren Reference / : Organic Chemistry Thomas N. Sorrell Reference 8Silverstein, WebsterKienmle, Bryce
Students are recommended to read recent publications on isolation, purification, total synthesis or mode of action of natural products. In addition, studens are recommended to review textbooks or references to develp their knowledge on organic chemistry.
: konokim.tohoku.ac.jp : masaru.enomoto.a2tohoku.ac.jp : skuwaharbiochem.tohoku.ac.jp : myamabiochem.tohoku.ac.jp @ Questions will be taken directly after each class or anytime through e-mail.Keiichi Konoki: konokim.tohoku.ac.jpMasaru Enomoto: masaru.enomoto.a2tohoku.ac.jpShigefumi Kuwahara: skuwaharbiochem.tohoku.ac.jp Mari Yotsu-Yamashita: myamabiochem.tohoku.ac.jpPlease change to @ when you e-mail.
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Food & Agricultural Immunology Joint Lecture 2
AAL-OAG507E
Basic and Applied studies on Food & Agricultural Immunology
This class aims to study the basic concepts of food and agricultural immunology and their application for drug-independent cultivation and food production. Each unit professor of the center and collaborative professor in Tohoku University will give the lectures weekly to introduce their specific research relating to immunology field.
Plants, Livestocks, Fish, Mollusks, Crustaceans, Innate immunity, Disease resistance, Pattern-recognition receptors, Allelochemical, Probiotics, Immunobiotics, Metagenome, Mucosal vaccine, Health impact assessment, Transcriptome, Metabolome, Bioinformatics, Epigenetics, Implementation, Risk communication
To understand the new study field of food and agricultural immunology and how to apply the concept for drug-independent cultivation and food production.
1. Overview of food & agricultural immunology.2. Introduction of immunology.3. Overview of immunobiotic application based on livestock immunology.4. Overview of vaccine development based on mucosal immunity.5. Immune regulation in the oral mucosa.6. Recognition and exclusion of pathogens in innate immunity.7. Overview of innate immune system of mollusks and crustaceans.8. Overview of immune system of fish and disease prevention study.9. Overview of plant immune system.10. Advancement of pest management system based on plant immunity.11. Overview of functional food evaluation.12. Overview of effects on human health relating to epigenetics.13. Overview of plant response to environmental cues.14. Ecology of viruses in natural environment.15. Overview of cooperation with society.
Participation30%, Reports70%
Participate in the International Food & Agricultural Immunology Lecture is highly recommended.
Textbook and references will be introduced by each professor.Video materials are also available.
It is important for students to acquire preliminary knowledge to prepare for class by reading relevant information and ocuments that are commonly available.
Instructors:Faculties in CFAI, Graduate School of Agricultural Science, Tohoku University, and Faculties in Tohoku University School of Medicine, Tohoku University Graduate School of Dentistry and Graduate School of Pharmaceutical Sciences, Tohoku University. Faculties in foreign institutions.
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Environmental science: a global concern 5th ed. Cunningham and Saigo, WCB/McGraw-Hill, Boston 1999
URLhttp://www.agri.tohoku.ac.jp/health/index-j.htmlhttp://www.agri.tohoku.ac.jp/kyousei/index-j.html
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Plant Science for Agricultural Production
In this course, students will learn about plant science for agricultural production.
Crop Science, Horticultural Science, Plant Pathology, Soil Science, Environmental Crop Science, Forest Ecology, Molecular Ecology, Chemical Ecology, Entomology
The aim of this course is that students establish their own idea about plant science for agricultural production.
Entomology Prof. Konno Crop Protection Prof. Honma Horticultural Science Prof. Kanayama Horticultural Science Asst. Prof. Nishiyama Plant Pathology Assoc. Prof. Ando Plant Pathology Asst. Prof. Miyashita Soil Science Prof. Nanzyo Environmental Crop Science Prof. Saito Environmental Crop Science Assoc. Prof. Ito Forest Ecology Prof. Seiwa Forest Molecular Ecology Assoc. Prof. Suyama Soil Science Assoc. Prof. Kanno Insect Chemical Ecology Assoc. Prof. Hori
100 Reports, short tests, or attendance
Students are required to prepare for class according to the goal and contents of each class.
No textbooks will be used.
The session time is limited and thereforeself-directed learning is important. Students arerequired to prepare and review for each class.
1 Organizer Prof. Yasuhiko Konno E-mail yasuhiko.konno.e8 tohoku.ac.jp2
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3 1998Janeway20102009 Fate 2015 5 2015N.F. Haard, B.K. Simpson: Seafood Enzymes, Marcel Dekker 2000 2010Lalli & Parsons: Biological Oceanography An Introduction, 2nd edition, Elsevier 1997 169 2011
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1 Gelvin 2012 Traversing the cell: Agrobacterium T-DNAs journey to the host genome. Frontiers in Plant
Science 3: 522 Madigan et al. 2014 Brock Biology of Microorganisms, Global Edition 14th /English, Pearson 3 Slonczewski & Foster 2014 Microbiology: An Evolving Science, 3rd Ed., W. W. Norton & Company
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NPO
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E-mail: [email protected]
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AAL-ENG521E
Ian Gleadall
A review of English as a tool in science and key ways to self-improve English skills
Gain confidence and enjoyment in using English, whether for formal research communication or as an enjoyable way to communicate informally at the international level.
Use, fun, negotiating, reading, speaking, listening, writing, presenting
Use "Falling Walls Lab. Sendai" as an objective for improving English skills, leading to a presentation in Sendai in the Falling Walls Lab. competition in Sendai Tohoku University, Katahira, and hopefully to the finals in Berlin, including free return airfare.
1. Introduction. Background to the course.2. Group discussions of good and bad presentations.3. Mini lecture on how to increase thinking time during conversations. Explanation of your own research.4. Preparing an interesting Curriculum Vitae CV.5. VAK learning styles. Discussion of presentation ideas.6. Preparations to apply for the Falling Walls Lab. competition.7. Final preparation for the Falling Walls Lab. presentation.8. Presentation practice.Methods: Some formal instruction, but mostly interacting with other students to teach and learn from each other.
Attendance, effort during lectures and performance of required tasks.
Your life until now, and your specific field of research.
As appropriate.
As instructed.
Students on this course are usually from very different backgrounds. There will be some mini-lectures and hints on how to improve English skills, but mostly practice and learning will occur through interaction with other students including international students from other departments.
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Pedogenesis and Soil Taxonomy, I, IIL.P. Wilding et al. , 1983, ElsevierSoil Taxonomy, 1999G.D.Smith Memorial Slide Collection, 1996
e-mail address: [email protected]
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Volcanic Ash Soils -Genesis, Properties and Utilizaiton. Shoji, Nanzyo and Dahlgren 1993
e-mail address: [email protected]
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2005 1992 1989
Brock Biology of Microorganisms. Madigan MT et al. eds., Prenticee-Hall, Inc., New Jersey 2006
URL http://www.agri.tohoku.ac.jp/health/[email protected]
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Kempthone Yamada BLUP BLUP REML
Linear Models, Searle, S.R., John Wiley & Sons
E314
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Physiological function for reproduction and immunity in aquatic organisms
Outline of recent topics of reproduction and immunity in fish and marine invertebrates from point of view of comparative endocrinology and immunology
Reproduction, endocrine system, innate immunity
Understanding of outline of physiological function of endogenous factors related to reproduction and immunity in aquatic organisms
15 Discussion of the following topics based on the scientific papersNeuropeptide hormonesOther neurohormonesSteroid hormoneOther hormonesReceptor mechanism; central nervous systemReceptor mechanism; GonadEndocrine factors for reproductionCentral nervous system and reproductionEndocrine control of reproductionInnate and acquired immunity in aquatic organismsBlood cell for innate immunity
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Humoral factor for innate immunityInteraction between cellular and humoral factors in innate immunityApproach to environment science from reproductive endocrinologyApproach to environment science from innate immunity
The academic achievement will be evaluated by the understanding and discussion of each topic
Reading papers provided in advance and related papers are strongly recommended before joining a class.
Papers will be provided in advance.
Preparation and review is strongly recommended.
1800 1900http://www.agri.tohoku.ac.jp/zoshoku/index-j.htmlE-mail: [email protected] may visit the office or contact via Email [email protected] anytime.
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Estuarine ecosystems and their components, Coastal system of rocky shore
Estuaries: Physical and biological prooertiesFate of macrophyte detritusEstuarine benthic systemsIntertidal rocky shoresSubtidal rocky shores
Ecology of Coastal Waters: With Implications For Management by K.H.Mann
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1-4 Marine ecology and production processes5-8 Fished species, life histories and distribution9-12 Population structure in space and time13-15 Stock assessment
Marine Fisheries Ecology by S. Jennings et al.Regime Shift - Fish and Climate Change by T. Kawasaki19829
e-mail [email protected]
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20082009 .Sea urchins: Biology and Ecology. J. M. Lawrence ed., 2013, Elsevier
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R. A. Day, B. Gastel: How to Write and Publish a Scientific Paper, 7th Edition, Greenwood Press.N.F. Haard, B.K. Simpson: Seafood Enzymes, Marcel DekkerM. Sakaguchi: More Efficient Utilization of Fish and Fisheries Products, Elsevier
1200 1300 : [email protected]@tohoku.ac.jp
[email protected] http://www.agri.tohoku.ac.jp/suika/index-j.html
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Economic development and agriculture
Main objective is to develop understanding of the agricultural transformation in developing Asia under the impacts of rapid economic growth, industrialization, urbanization, global warming, and globalization.
economic growth, agriculture, market economy, capitalism, land ownership, cooperative
Students are expected to deepen their understanding on the difference of the social systems or institutions among countries and/or areas. Taking account into such diversified characteristics of economy and agriculture in developing Asian countries, students are expected to concert alternative models and policies as well as to review the general models and policies of development.
Introduction and briefing on a textbook adoptedThe agrarian origins of modern JapanCommercial agriculture and land ownershipThe establishment of Japanese capitalism and agricultureJapanese modern agricultural policyThe transformation of Japanese capitalism and agricultureThe industrialization of Japan and agricultureThe Great Depression and Japanese agricultureRegulation of agriculture under the WW 2ndReconstruction of Japanese economy and land reformEstablishment of modern agricultural cooperation in JapanRapid economic growth and agricultureJapan as a major economic power and a minor agricultural nationRecent situation of Japanese agricultureWrap-up discussion on the adopted text
Presentation of textbook 50%, presentation of homework 30%, and discussion 20%
Students need to learn basic Micro and Macro Economics prior to taking this course.
It will be announced at the first class.In this year, we use textbooks about Japanese agricultural development history.
Every student is requested to give a presentation in the class once or twice per semester. When a student is appointed as a reporter, he or she must prepare a handout of report based on the assigned chapter of adopted textbook and its related papers.
Office hour: Please make an appointment with each professor by e-mail. FUYUKI e-mail: [email protected] office: E213TAKASHINO e-mail: [email protected] office: A201 Our offices are located on the 2nd floor of Multidisciplinary Research Laboratory of
Agricultural Science K01 building in Aobayama Campus.
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Andrew Barkley and Paul Barkley 2013 Principles of Agricultural EconomicsRobert E. Evenson ed. 2007 Handbook of Agricultural Economics Vol.3.
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A.S, PullinJ.C.Avise
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8 10 New Breeding Technique
2013
E408 http://www.agri.tohoku.ac.jp/bioadp /index-j.htmlE-mail: [email protected]
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Current topics in biological oceanography
Understanding the latest knowledge of biological oceanography.
Marine environment and adaptation of marine organisms, Dynamics of marine ecosystems, Global warming and marine ecosystem, Disturbances
Understanding the relationships between marine organisms and environment and responses of marine ecosystems against environmental change.
Characteristics of marine environment compared to terrestrial environment Function of lower producers that control the stability of marine ecosystem Responses of benthic community against the marine environmental change Relationships between global warming and marine ecosystems Natural and anthropogenic disturbances
Read and discussion ability.
Acquire basic knowledge on oceans and organisms living in them.
Introduce the papers before the seminar.
Acquire basic knowledge on oceans and organisms that live there.
Office hour: 3-5pm Wednesday, but whenever I am in the officemail address: [email protected]
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yasuhiko.konno.e8 tohoku.ac.jp hori tohoku.ac.jp
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Grasses and Grassland Ecology, David J. Gibson, Oxford University Press, 2008Grazing Management 2nd Ed. John F. Vallentine, Academic Press, 2000
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3http://www.agri.tohoku.ac.jp/rikuken/[email protected]
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Mechanisms of nitrogen metabolism and its regulation in plants: from molecular to plant level
1 2 3 1 2 3
30, 20203015 15
Biochemistry and Molecular Biology of Plants, eds. by Buchanan, B.B., Gruissem, W.G. and Jones, R.L., publisher
American Society of Plant Physiologists, Maryland, USA 2000 Plant Physiology Third Edition, eds. by Taiz, L. and Zeiger, E., publisher Sinauer Associates, Inc.,
Sunderland, Massachusetts, USA 2002Mineral Nutrition of Higher Plants, Marschner, H., Academic Press, London, UK 1995
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E504W510W512http://www.agri.tohoku.ac.jp/cellbio/index-j.htmE-mail [email protected]; [email protected] [email protected]
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Plant immune system, Disease resistance geneAvirulence gene, Effectors, Pathogen-associated molecular pattern, RNA silencing
Plant-pathogen interaction. 1Plant-pathogen interaction. 2Avirulence gene and effectors. 1Avirulence gene and effectors. 2Pathogenesis-related proteins and defense responses. 1Pathogenesis-related proteins and defense responses. 2Function of disease resistance proteins. 1Function of disease resistance proteins. 2Signal transduction pathways for defense responses. 1Signal transduction pathways for defense responses. 2Molecular mechanism of plant immune system. 1Molecular mechanism of plant immune system. 2Determinants of tipping balance in host-microbe interactions. 1Determinants of tipping balance in host-microbe interactions. 2Trained innate immunity in plants
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1 Plant Pathology, Eds., Agrios, G.N. 2005, Elsevier, 2 2006, , 3 Induced Resistance for Plant Defense. Eds., Walters, D., Newton, A. and Lyon, G. 2007, Blackwell
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Post-transcriptional gene silencing, Dominant resistance genes, Viral evolution, Virus replication, Priming, Induced resistance, Bacterial panicle blight
Molecular mechanism of plant immune system against virus infection: Post-transcriptional gene
silencing PTGSMolecular mechanism of plant immune system against virus infection: Function of PTGS suppressors Evolution of host plants and pathogens viral replication: Dominant resistance genes, Recessive
resistance genesvolution of host plants and pathogens viral replication: Coevolution, Fitness costMechanisms of viral evolution: Mutation rate, Genetic bottlenecksMechanisms of viral evolution: Mathematical modelingVirus replication: in vitro replication systemVirus replication: Mathematical modelingAnalysis of primed activation of RNA silencing components: Regulation of Gene expressionAnalysis of primed activation of RNA silencing components: Chromatin modificationMolecular mechanism of induced resistance to secondary infection: Signaling molesules Molecular mechanism of induced resistance to secondary infection: Oxidative burst and signal
transcudtion Molecular mechanism of induced resistance to secondary infection: Long-distance signaling
moleculesSeed-disinfection using plasma irradiation for suppression of rice diseases: Bakanae diseaseSeed-disinfection using plasma irradiation for suppression of rice diseases: Bacterial panicle blight
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1 Plant Pathology, Eds., Agrios, G.N. 2005, Elsevier, 2 Induced Resistance for Plant Defense.
Eds., Walters, D.,Newton, A. and Lyon, G. 2007, Blackwell
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20112014
20112014
10 12 [email protected]@tohoku.ac.jp
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II II III IV V VI I II III III IV
iP 80
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http://www.agri.tohoku.ac.jp/keitai/index.htmle-mail [email protected]
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Cell Metabolism Comparative animal nutrition and Metabolism P.R. Cheeke & E.S. Dierenfeld2010
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1200 1300 E403 2http://www.agri.tohoku.ac.jp/aninutr/index-j.html3 e-mail [email protected]
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Nature, ScienceMolecular Biology of The Cell, Bruce Alberts et al Garland Science
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PubMed
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1 Brock, Biology of Microorganisms 14th edition Madigan M et al. PEARSON 13 14 2 2015
15 17 http://www.agri.tohoku.ac.jp/microbio/[email protected]
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2010
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20092003
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Bio preservation
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Probiotics: immunobiotics and immunogenics, CRC Press, Lactic acid bacreria and Bificobacteria Caister Academic Press, Bioactive components of milk, Springer
17 18 URL http://www.agri.tohoku.ac.jp/douka/index-j.html [email protected] [email protected] [email protected] 28 29
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E512 N505 [email protected] [email protected]
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Nutrition ReviewsPhysiology
Trends in biochemical sciences, Trends in endocrinology and metabolism
Nutrition Reviews , Physiology ,Trends in biochemical sciences, Trends in endocrinology and metabolism
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2http//www.agri.tohoku.ac.jp/eiyo/index-j.html
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16 17 : E : [email protected]://www.agri.tohoku.ac.jp/kinoubunshi/index-j.html
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Current research of natural products Isolation, structure determination, synthesis, mode of action, biosynthesis
2 NMR MS J NOE The course offer the opporunity to lean the current and cutting edge natural products research for isolation, structure determination, synthesis, mode of action, and biosynthesis. Especially, the students learn the basic skills of determine the strctures of the organic compounds using several 2D NMR tachniques and MS spectrometry.
NMRMS
natural products chemistiry,isolation, structure determination, synthesis, mode of action, biosynthesis, NMR, MS spectrometry
Students will understand how to determine the structures of low molecular weight organic compounds, and to study of current natural product chemisitry from diversified standpoints.
2D NMR 1 Structure analysis of natural products using 2D NMR, basic skillMari Yotsu-Yamashita 2D NMR Stereo_structure analysis of natural products using 2D NMR, application skillMari Yotsu-
Yamashita MS Application of several mass spectrometry to structure analysis of natural productsMari Yotsu-
Yamashita Method for isolation and purification of natural productsMari Yotsu-Yamashita NMR, MS Application of NMR and MS spectrometry to biosynthetic study of natural productsMari Yotsu-
Yamashita Discussion for the topics of the annual symposium on the chemistry of natural productsMari
Yotsu-Yamashita - : Bioassay of natural products - Cell culture Keiichi Konoki - : Bioassay of natural products - Heterologous expression Keiichi Konoki - : Bioassay of natual products - High through-put screening Keiichi Konoki
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Classical but unforgettable natural product chemistry Keiichi Konoki Frontier of natural product chemistry in Japan Keiichi Konoki -1 Representative organic reactions and retrosynthetic analysis-1 Shigefumi Kuwahara -2 Representative organic reactions and retrosynthetic analysis-2 Shigefumi Kuwahara Development of chemosensors usig natural products Masaru Enomoto Drug discovery research based on multivalent effect of natural products Masaru Enomoto
Drug discovery research based on multivalent effect of natural products Masaru Enomoto
1D NMRMS
Review the basic method for determination of the structures of organic compounds using 1D NMR and MS spectrometry.
8Silverstein, Webster, Kienmle, Bryce
Students are required to prepare for class according to the contents of each class.
1 Question will be taken directly after each calss or anytime through e-mail.
2E-mail [email protected] [email protected], [email protected] [email protected]
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Total synthesis, structural determination, and biological activity of natural products
This class provides students with advanced knowledge on synthetic design, structural determination, and biological activity of natural organic molecules. The contents include lectures by professors, presentation by students on topics talked in Symposium on the Chemistry of Natural Products, and English listening training using ACS Audio Courses.
natural products, total synthesis, structural determination, analysis of bioactivity
The purpose of this class is to help students acquire advanced knowledge on total synthesis, structural determination, evaluation of biological activity of natural products. This class is also aimed at helping students to improve their presentation and English listening ability.
History of Symposium on the Chemistry of Natural Products and some historic presentations Kuwahara Representative topics talked in the Symposium on the Chemistry of Natural Products. Enomoto -1 Presentation by students and discussion-1 Kuwahara -2 Presentation by students and discussion-2 Kuwahara -3 Presentation by students and discussion-3 Kuwahara -4 Presentation by students and discussion-4 Kuwahara -5 Presentation by students and discussion-5 Kuwahara -6 Presentation by students and discussion-6 Enomoto -7 Presentation by students and discussion-7 Enomoto -8 Presentation by students and discussion-8 Enomoto
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70
2
29
ABB-APC510J
-9 Presentation by students and discussion-9 Enomoto -10 Presentation by students and discussion-10 Yamashita -11 Presentation by students and discussion-11 Yamashita -12 Presentation by students and discussion-12 Konoki -13 Presentation by students and discussion-13 Konoki
50%10%40%Evaluation is performed based on presentation 50%questions and answers 10% and attendance 40%
Students need to understand basic organic chemistry organic reactions and spectroscopic analysis taught in the undergraduate program.
Textbook Abstracts of Papers, Symposium on the Chemistry of Natural Products.The Challenge of Synthesis: Techniques and StrategiesB. M. Trost, ACS Audio Course, The American Chemical Society
Students need to deepen the knowledge provided in the class by perusing the original articles and reviews related the topics presented in the class.
, [email protected] [email protected]@m.tohoku.ac.jp [email protected] get in touch with each professor by e-mail when you have questions.
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71
2
ABB-APC511J
Synthetic organic chemistry and natural products chemistry
This class provides students with advanced knowledge on C-C bond formation, stereochemical control, functional group transformation, and synthetic design which are useful for the total syntehsis of structurally complicated organic molecules including bioactive natural products.
- C-C bond formation, Stereochemical control, Functional group transformation, Retrosynthesis
The main purpose of this class is to help students acquire advanced knoledge on the mechanism of representative organic reactions and fully utilize them for synthetic design of structurally conplicated organic molecules.
- -1Carbon-carbon bond forming reactions-1 - -2Carbon-carbon bond forming reactions-2 - -3Carbon-carbon bond forming reactions-3 -1Stereocontrol in orgnaic synthesis-1 -2Stereocontrol in orgnaic synthesis-2 -3Stereocontrol in orgnaic synthesis-3 -1Functional group transformation-1 -2Functional group transformation-2 -3Functional group transformation-3 - -1Practical carbon-carbon bond forming reactions-1 - -2Practical carbon-carbon bond forming reactions-2 - -3Practical carbon-carbon bond forming reactions-3 -1Design of multistep synthesis-1 -2Design of multistep synthesis-2 -3Design of multistep synthesis-3End-of-term examination
Evaluation is performed based on an end-of-term examination.
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72
2
ABB-APC511J
Students need to fully understand organic chemistry taught in the undergraduate program.The lectures are given on the opremise that students have read through a textbook such as Warren-Organic Chemistry Oxford University Press.
: Textbook: Daigakuin-Kogi Yuukikagaku, 2nd ed.Ryoji Noyori et al. Eds, Tokyo Kagaku Dojin.
Students need to deepen the knowledge provided in the class by perusing the original articles related to the topics presented in the class.
[email protected] get in touch with Prof. Kuwahara by e-mail when you have questions.
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73
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29
ABB-AGC512J
DNA
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ABB-APS513J
1 2 3 4 5 6 7 8 9 10 11 12 2 13 2 14 15
8 1000
12198731977419945Conservation and the Genetics of Populations 2006: FW Allendorf and G Luikart, Blackwell Publishing 19986
E-mail address [email protected] [email protected] [email protected] [email protected]
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75
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29
ABB-AGC514J
E-mail [email protected]
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76
2
29
ABB-AGC514J
123
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77
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77
2
AAL-BAM523J
DNA
DNA
UNIX DNA
30 70
- 3 Python NGS Surfers Wikihttp://cell-innovation.nig.ac.jp/wiki/tiki-index.php
http://nagasakilab.csml.org/ja/[email protected] 29 4 12 29 7 19 1440 1610 6 1
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79
2
29
AAL-OAG702J
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80
2
29
AAL-APC704J
Chemistry and Biology on Bioactive Natural Products
This class provides students with basic and advanced knowledge on natural products chemistry that includes isolation, structural determination, biosynthetic pathway, action mechanism, and chemical synthesis of biologically active natural products. Basic knowledge for writing research papers will also be presented.
Natural organic compounds, Bioactivity, Structural determination, Biosynthesis, Total synthesis, Research paper writing
The purpose of this class is to help students acquire methodologies for structural determination and synthesis of natural products, understand up-to-date knowledge on natural products chemistry, and gain ability to write their research papers.
Total synthesis of isoprenoids-1 Kuwahara Total synthesis of isoprenoids-2 Kuwahara Total synthesis of polyketides-1 Kuwahara - Total synthesis of polyketides-2 Kuwahara - Total synthesis of alkaloids-1 Enomoto - Total synthesis of alkaloids-2 Enomoto Total synthesis of other classes of natural products Enomoto How to write scientific papers on synthetic organic chemistry Kuwahara - Isolation and structural determination of marine natural products-1 Yamashita - Isolation and structural determination of marine natural products-2 Yamashita Biosynthesis of alkaloids Yamashita
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81
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29
AAL-APC704J
Biosynthesis of bioactive natural products Yamashita - Isolation and structural determination of cytotoxic substances-1 Konoki - Isolation and structural determination of cytotoxic substances-2 Konoki How to write scientific papers on isolation and structural determination of natural products
Yamashita
Evaluation is performed comprehensively based on submitted reports, short tests, and so on.
Students need to understand the fundamentals of natural products chemistry such as structural determination by spectroscopic methods and basic organic reactions.
No textbook is used. Reference books and articles will be suggested when needed.
Students need to deepen the knowledge provided in the class by perusing the original articles and reviews related the topics provided in the class.
[email protected] [email protected]@m.tohoku.ac.jp [email protected] get in touch with each professor by e-mail when you have questions.
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82
International Food & Agricultural Immunology Lecture 2
AAL-OAG807E
International Food & Agricultural Immunology Seminar and Special Lecture
To attend the international symposium organized by CFAI and discuss issues on each topics in English. In addition, professors in foreign institutions will give the special lectures relating to food and agricultural immunology fields.
Plants, Livestocks, Fish, Mollusks, Crustaceans, Innate immunity, Disease resistance, Pattern-recognition receptors, Allelochemical, Probiotics, Immunobiotics, Metagenome, Mucosal vaccine, Health impact assessment, Transcriptome, Metabolome, Bioinformatics, Epigenetics, Implementation, Risk communication
To attend the international symposium/congress, special lectures and discuss about each topics in "Salmon-Type Lecture".
International symposium and special lectures1 International Symposium: 1 day Participants: Students, Post-doc, Faculty members in Tohoku University and Other University in Japan Venue: Appropriate place in Tohoku University Speakers: Faculties in foreign institutions, domestic university/institute and faculties in CFAI2 Special lectures by Faculties in foreign institutions3 Problem Based Learning PBL in "Salmon-Type Lecture".
Participation30%, Reports70%
Participate in the Food & Agricultural Immunology Joint Lecture is highly recommended.
Symposium abstract and handouts of special lectures will be distributed.Video materials are also available.
Students are required to prepare for class according to the goal and contents of each class.
Instructors: Faculties in foreign institutions, domestic university or institute, and faculties in CFAI,
Graduate School of Agricultural Science, Tohoku University, and other Schools of Tohoku University.
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