病原生物学Medical Microbiology and Parasitology

Part I: Medical Microbiology

Part II: Medical Parasitology

Medical Microbiology

Xiao-Kui GUO(郭晓奎）Dept. of medical Microbiology and Parasitology

E.mail: xkguo@shsmu.edu.cn

Tel: 776712

Office: 5-511

Introduction

Microorganisms(Microbes)MicrobiologyMedical Microbiology

What is Microorganisms

Microorganisms are creatures that are not directly visible to the unaided eye, with dramatical biologic diversity.

Viruses , bacteria, fungi, protozoa and some algae are all in this category

All with the exception of plants and animals

Distribution of microorganisms

Air Soil

Water Animals

Human body

100m

300m

1400m

2100m

3150m

4050m

6000m

Microorganisms and Human Beings

Beneficial activities: Most microbes are of benefit to human beings, some are necessary( nitrogen, carbon cycles, etc)

Harmful activities: A portion of microbes cause diseases and are poisonous to human, and these are really that concern us in the study of medical microbiology, etc.

Microbiology

Microbiology is the biology of microorganisms. It is a bioscience for the study of the evolution, Classification , morphology, physiology, genetics, ecology of microbes under certain definite conditions, The law of their life activities, and their interaction with human being, animals or plants as well as with natural environment.

The Importance of Microbiology

Environment Medicine Food Industry Biotechnology Research

History of Microbiology

Experience phase经验时期

Experimental phase实验时期

Modern phase现代微生物学时期

Experience phase

Experimental phase

Leeuwenhoek Pastur Koch Lister

Koch’s postulates

The microbe must be found in the body in all cases of the disease

It must be isolated from a case and grown in a series of pure culture in vitro

It reproduce the disease on the inoculation of a late pure culture into a susceptible animal

The microbe must be isolated again into pure culture from such experimentally caused infection.

艾利希， 1910

Modern phase

Fei-Fan Tang

Emerging and Reemerging Infectious Disease

AIDS Tuberculosis Hepatitis Gastric ulcer SRAS

Medical Microbiology The medical microbiology is one of the essential

basic sciences for medine. It is the study of Biological characteristics of microorganisms and their relationships with human hosts

Medical Bacteriology Medical Viriology Medical Mycology Parasitology Immunology

Purpose for learning of Medical Microbiology

Medical Microbiology

Textbook

http://basic.shsmu.edu.cn/passw/micro2/index.asp