รวมข้อสอบ pharmacy licence--เฉลย dm thyroid

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O S P E เทคนิคทางเภสัชกรรม เรื่อง การชั่งสาร 1.1 การชั่งผงยาโดยการเลือกใช้กระดาษ การใช้ช้อนเขา และการเคาะผงยาลงเมื่อใกล้ถึงนําหนัก ที่ต้องการ . การชั่งด้วยเครื่องชั่งไฟฟ้า (Top Loading Balance) - ปรับสมดุลของเครื่องชั่ง เครื่องชั่งไฟฟ้าส่วนใหญ่ปรับโดยการหมุนสกรูที่ขาซ้ายขวาของเครื่องชั่ง ให้สังเกตฟองอากาศที่เป็นตัวบ่งชีสมดุลอยู่ตรงกลางเครื่องหมายวงกลม หลักการหมุนปรับคือ การหมุนตามเข็มนาฬิกาเครื่องชั่งจะยกสูงขึ้น การ หมุนทวนเข็ม เครื่องชั่งจะลดต่ําลง (ในขั้นนี้เนื่องจากเวลาจํากัด อาจมีการปรับเครื่องชั่งสมดุลให้แล้ว ซึ่งจะแจ้งให้ ผู้สอบทราบ ในกรณีนี้ก็อาจข้ามขั้นตอนนี้ได) - พับกระดาษชั่ง ใช้กระดาษสะอาด ตัดเป็นรูปสี่เหลี่ยมผืนผ้า โดยทั่วไปขนาด 8 ซม. X 10 ซม. พับริมด้านข้าง (ด้านยาว) เข้ามาทั้ง 2 ด้านๆละ 1 ซม. พับด้านที3 เข้ามา 2 ซม แล้วพับกลับออกไป 1 ซม. คลี่รอยพับออก จับด้านที3 จีบซ้อนให้เป็นมุมกระทง ทําทั้ง 2 มุม แล้วพับส่วนที่ยาวเกินอยู่ลงเพื่อให้กระทงแข็งแรงขึ้น - เขียนชื่อยาและน้ําหนักที่ต้องการชั ่ง โดยเขียนลงส่วนที่พับไว้เพื่อหลีกเลี่ยงสารเคมีสัมผัสกับที่ใช้เขียน - Tare เครื่องชั่ง (auto-zero) หรือปรับน้ําหนักเครื่องชั่งเป็น 0 - อ่านฉลากขวดยา หยิบขวดยา เปิดฝาขวด วางฝาหงายบนพื้นที่สะอาดหรือบนแผ่นกระเบื้องวางขวดยา อ่านฉลากอีกครั้งให้แน่ใจ จับช้อนด้วยมือ ข้างที่ถนัด ลักษณะคว่ําเต็มมือ ให้นิ้วชี้วางทอดคว่ําบนด้ามช้อนเขาตักยาจากขวดยา ซึ่งถือในมือข้างที่ไม่ถนัด เคาะ นิ้วชี(ลักษณะคว่ํามือ) ให้ผงยาค่อยๆลงบนกระดาษ โดยเฉพาะเมื่อใกล้ถึงนําหนักที่ต้องการ ปิดกระจกกันลม(ถ้า มี) สังเกตค่าน้ําหนักจากหน้าปัดตลอดเวลาที่ชั่ง - เมื่อได้ปริมาณที่ต้องการ ยกกระดาษชั่งยาออกจากจานชั่ง ปิดกระจกกันลม ปรับน้ําหนักเป็นศูนย์ ตามเดิม ปิดฝาขวดยาให้สนิท ทําความสะอาดด้วยแปรงปัดถ้ามีผงยาหกบริเวณเครื่องชั่ง อ่านฉลากอีกครั้ง . การชั่งด้วยเครื่องชั่ง 2 จาน - พับกระดาษชั่ง ใช้กระดาษสะอาด ตัดเป็นรูปสี่เหลี่ยมผืนผ้า โดยทั่วไปขนาด 8 ซม. X 10 ซม. พับริม ด้านข้าง (ด้านยาว) เข้ามาทั้ง 2 ด้านๆละ 1 ซม. พับด้านที3 เข้ามา 2 ซม แล้วพับกลับออกไป 1 ซม. คลี่รอย พับออก จับด้านที3 จีบซ้อนให้เป็นมุมกระทง ทําทั้ง 2 มุม แล้วพับส่วนที่ยาวเกินอยู่ลงเพื่อให้กระทงแข็งแรงขึ้น - เขียนชื่อยาและน้ําหนักที่ต้องการชั่ง โดยเขียนลงส่วนที่พับไว้เพื่อหลีกเลี่ยงสารเคมีสัมผัสกับที่ใช้เขียน - วางกระดาษชั่ง ที่เหมือนกันบนจานทั้ง 2 ด้าน - ปรับสมดุลของเครื่องชั่ง ให้สังเกตเข็มชี(indicator) ให้ตรงขีดศูนย์หรือตรงกลาง (ในขั้นนี้เนื่องจาก เวลาจํากัด อาจมีการปรับเครื่องชั่งสมดุลให้แล้ว ซึ่งจะแจ้งให้ผู้สอบทราบ ในกรณีนี้ก็อาจข้ามขั้นตอนนี้ได) - เติมตุ้มนําหนักลงบนจานชั่ง

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O S P E 1.1 . (Top Loading Balance) - ( ) - 8 . X 10 . () 2 1 . 3 2 1 . 3 2 - -Tare (auto-zero) 0 - () () - . 2 - 8 . X 10 . () 2 1 . 3 2 1 . 3 2 - - 2 - (indicator) ( ) - Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 2- () - 1.2 mineral oil glycerin w/w (draining time) (specific gravity) 2 2 - 2.1 - 10, 25, 50, 100 ml - - ( ) ( )- - lower meniscus upper minicus - - O S P E calibration Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 32.2 3 , , Mineral oil 1. - lower meniscus () 2. (potassium permanganate),iodine solution - upper meniscus () 3. mineral oil, glycerin - lower meniscus () calibration 2.3 calibration Calibrate 0.8 ml 10 ml dropper pipette burette - 10 ml () 2 ml - 2 ml 0.5 - Calibrate - 20% -cylinder 2 ml cylinder 10 ml - 4 cylinder (2 ml) - Dropper - Dropper cylinder ( 2 ml) cylinder - - 2 ml ..... 0.4 ml ...... Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 4 aliquot aliquot 2.4.1 aliquot - - 2.4.2 aliquot - - reconstitution O S P E 3.1 1. - (staining) (porcelain mortar & pestle)- - - - spatula spatula - camphor pulverization by intervention Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 52. - trituration (glass mortar & pestle) - geometric dilution () slab & spatula spatulation - slab slab slab spatula spatula spatula spaula spatula spatula - geometric dilution 3.2 geometric dilution slab lactose 2 1. (Mortar & Pestle) - - * * -() - - - -spatula Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 62. Slab & Spatula Spatulation spatula slab Slab & Spatula - slab slab spatula spatula ( ) - slab spatula slab - - Levigation 3.3 levigate ointment cream slab (levigation) (levigating agent) slab & spatula - glycerin, mineral oil - slab slab spatula spatula spatula spatula - 2-3 (smooth paste) - slab spatula geometric dilution spatula spatula livigation livigate livigating agent 1. - o/w creambase glycerin, propylene glycol,sorbitol livigating agent - w/o creambase mineraloillivigatingagent 2. 10% meltedbaselivigatingagent livigatingagent Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 73. livigatingagent 4. livigating *** O S P E 4.1 1. 2 plain filter plaited filter (filtrate) Plain Filter - 60 Plaited Filter - 16 32 () 2. - 0.5-1 . - supportory funnel - - 45 - 3. - 2 - - 4. - 2 4 Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 8O S P E 6.1 1. 1) (direct heat) - (burner) (hot plate) - collar - nonluminous flame - (tripod) wire gauze - wire gauze - wire gauze beaker, casserole 2) (water bath) 100 wax, fat - water bath wire gauze - () 2. - 100 - casserole beaker (order of melting point) - - () Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 9O S P E 7.1 - - (approximate volume) 3/4 - - 7.2 - stock solution- pipet - - AlcoholUSP=95%, BP=96% alcohol70%95 %50ml 95 %70 (ml) 70 % 0%25 (ml) 95 (ml) Alcohol 70% 50 ml alcohol70 % 95 AlcoholUSP 70 50 Alcohol USP (70 50) / 95 = 36.84 (ml) 50 36.84 = 13.16 (ml) 1. alc. cylinder (cylinder ) 2. Cylinder 3. alc. Cylinder Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 10O S P E Dosage Form / (solid dosage forms) 1. Powders : ORS 2. Granules : ... Fluimucil(Acetylcysteine) Granules 3. Hard Gelatin Capsules : (hard capsules) 4. Soft Gelatin Capsules : (soft capsules) 5. Tablets : Lozenges : strepsil Mybacin Pills : Pastilles : Vaginal suppository tablets : 6. Coated Tablets : Sugar coated tablets : Vitamin B complex Film coated tablet : sugar coated tablet Ibuprofen Enteric coated tablets : diclofenac, omeprazole - : Effervescents Tablets Calcium Powders - 1. Solutions : (waters) (elixirs) (spirits) 2. Syrups : emulsions suspensions Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 11- 1. Mixtures : (Brown mixtures) (Mixture Carminative) 2. Suspensions/Magmas : Suspension 3. Emulsions : mineral oil 4. Lotions : 5. Liniments : 6. (colloids) 1. Creams : 2. Ointments : 3. Pastes : triamcinolone oral pastes (Kenalog) 4. Gels : 5. Suppositories : Rectal suppositories (Tablets) 1. Inhalations : - Aerosol Inhalations : Aerosol Ventolin MDI 2. Nebulizer nasal drops 3. Ear/Eye drops : 4. 5. (controlled released products) 6. (drug delivery systems) : S ( ) technical term Effervescent Tablets Effervescent PowdersComprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 12/ enteric coated tablet omeprazole Enteric coated granules in hard gelatin capsules ( ) Eno,Vitamin CEffervescentpowderFumucil, Acetyicysteinegranule Calamide,MOMSuspension / magma IbuprofenFilm coatedtablet VitaminB complexSugarcoatedtablets VitaminESoftgelatincapsule Lozenges Liniment ORS, Powder Pills ProctosedylSuppository Canestensuppo Vaginal tablet Nebulizernasaldrop / / immediate container closure (strength) (quality) (purity) Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 13 child resistant packaging tamper resistant packaging tamper evident packaging tamper proof packaging light-resistant container light-resistant container protect from light () well-closed container tight container (efflorescence) (deliquescence) hermetic container tight container single dose hermetic container single-unit container (single dose) immediate container / tamper-resistant packaging single-unit container / (lot number) single-dose container single-unit container single-dose container pre-filled syringes, cartridges, fusion-sealed containers closure-sealed containers unit-dose container single-unit container multiple-unit container multiple-dose container multiple-unit container Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 14 (PROTECT FROM LIGHT) / - Nifedipine- Glyceryl Trinitrate- Nitrendipine- Propranolol - Metoprolol - Phenytoin- Dopergin- Doxycyclin- Eltroxin - Essentiale- Metronidazole- Fludrocortisone (FLORINEF) - Zalcitabine- Hydroxyurea- Terazosin- Indomethacin Sustain-Released Tablet- Isosorbide Dinitrate - Isoniazid- Digoxin - Thioguanine- Furosemide - Gemfibrozil Tablet- Madopar 250 mg. , HBS - Meladinine- Methotrexate - Pizotifen- Naproxen - Hydroxychloroquine Sulfate - Mercaptopurine- Zidovudine - Calcitriol- Rowatinex - Septrin DS- Sinemet125,275 mg.- Prochlorperazine Maleate - Methimazole - Thyroid Hormone- Carbamazepine- Atenolol - Tetracyclin- Vitamin A - Vitamin C- Vitamin E- Multivitamin- Salbutamol / 1. Controlled release dosage forms AdalatCR (30 mg.)Addi-K Bezalip Retard BricanyDuruleCardilSR() CodiprontDimetappExtentab DynacircSRO (5 mg)InderalLAIndocid R. soptinRetard ()Pluryle KKaliumSR KinidinDuruleMadoparHBSMST(MorphineSulfate) Oruvail (100,200 mg.)PanbesyPlendil ( Munobal) PonderalPacapsRoxil(75,150 mg.) Tegretol CR ()VolmaxVoltaren 100 mg 2.Enteric-Coated Dosage Forms Aspent ,Dicetel ,Dulcolax ,Erytab Salazopyrin ,Voltaren 25 mg ,Vivotif Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 15 1. extended-release controlled-release, modified-release CR, LA, MR, SR, XL XR 2. enteric coated 3. sugar coated 4. (Sublingual) 5. effervescent AlfuzosinHClXatralSRSanofi - Synthelabo5. Xatral XLSanofi - Synthelabo10. AmbroxolHClBronchoprontMack75. AscorbicacidC - willWillPharma/SPB Pharma 500. BarnidipineHClHypocaYamanouchi10,15 . BezafibrateBezalipretardRoche400. CarbidopaSinemet CRMerckSharp & Dohme(carbidopa levodopa 50. levodopa200.) CefaclormonhydrateDistaclorMREliLilly 375. Cefaclor Vercef MRRanbaxyunichem375. ClarithromycinKlacid Abbott500. CodeineCodiprontMack(codeine phenyltoloxamine300. phenyltoloxamine10.) Co - dergocrinePerenanSanofi - Synthelabo2.5. DiclofenacsodiumRemethanRemedica100. Voltaren SRNovartis 75. * DiltiazemHClAngizemSunPharma30,60. CardilCROrion120. * Cascor XLRanbaxyUnichem 120,180,240. Dilem SRDouglas/TTN60,120. Herbesser90SR TanabeSeiyaku90. D - norpseudoephedrine Mirapront Mack20. FelodipinePlendil AstraZeneca2.5 , 5 , 10. * FluvastatinLescolXLNovartis 80. Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 16GliclazideDiamicronMR Servier30. * IndapamideNatrilixSRServier1.5. * IsosorbidedinitrateISO - MACK - retardMack20,40. MonolinSRBerlinPharm20,40,60. MonotrateOD SunPharma50. Isosorbide - 5 mononitrate ImdurAstra ZenecaDurule60. * IsoxsuprineresinateDuvadilanDuphar - Interfran40. KetoprofenOruvail 100AventisPharma 100.Metoprolol100mgStada100. Metoprolol200mgStada200. MorphinesulfateMst contnustm 10 mg Astamedica10. * NicardipineHClCardepineWestmont/GreatEastern40. NifedipineAdalatCR Bayer30 ,60. Adalat RetardBayer20. CalcigardTorrent20. FenamonSRMedochemie20. Nifecard retardLek20. Nifecard T20 Stada20. NifelatRRemedica20. NyefaxDouglas/TTN20. OmeprazoleMg LosecMUPSAstraZeneca20.* OrphenadrineHClNorflex3MPharma100. PentoxifyllineAgapurineSlovakofarma400. FlexitalSunPharma400. Trental 400AventisPharma 400. * PhentermineresinatePhenterminetrenkerTrenker15,30 . PhenylephrineHCl ,RhinoprontMack Carbinoxaminmaleate(4 + 20 . ) Piribedil TrivastalretardServier50. * PotassiumchlorideAddiKLeo50. * PropranololHCl InderalLAAstraZeneca80,160. SalbutamolVolmaxGlaxoSmithkline4. SodiumvaproateDepakinechronoSanofi - Synthelabo500. * TheophyllineAerobinmitePharmasan / TTN 200. NuelinSR3MPharma200* , 250.RetafyllineCR Orion200,300. XanthiumSMB200 * , 400 . TramadolHClTradonalSRASTAMedica50,100,150. Tramal retardSanofi - Synthelabo100. VenlafaxineHCl EfexorXRWyeth - Ayerst75. :MIMSThailand(2002) * Diclofenac Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 17DifeleneThaiNakornPatana25,50. DifenacTPDrug25,50. Difeno Milano25 . DosanacSiamBheasach25 * , 50. Fenac LBS25,50. InfanacBiolab25. MedarenMedicalSupply25. PosnacPose25,50. PutarenThaiPDChemicals25. RemethanRemedica25. RumatabPharmaland25,50. Veenac 25,50ProgressLab25,50. Voltanac PharmasantLab 25,50. VoltarenNovartis 25,50. VoltamedMedifive 25. Didanosine(DDI)Videx ECBristol - MyersSquibb250 , 400.DimenhydrinateVominarCharoenBhaesaj50. ErythromycinEry - tabAbbott250. IndomethacinMetindoKenyaku2. LansoprazolePrevacidTakedaChemical15,30.industries MesalazineSalofalkFalk250,500. EsomeprazoleNexiumAstraZenecaMUPS20 , 40. OmeprazoleMiracidBerlinPharm20.Papain + pepsinPapytazymeAnglo - FrenchDrugs (30 + 50 . ) PotassiumchlorideEnpott RanbaxyUnichem500. SerratiopeptidaseDanzenTakeda5. Danzyme - 5ProgressLab5. Serratiopeptidase Danzyme - 10ProgressLab10. MedizymeUtopian5. RodasePond'sChemical5. SeramedMedifive 5. SerradaseECTSiamBheasach5. SerrapepAsianPharm5. SerrinMacroPhar5. SodiumvaproateDepakine Sanofi - Synthelabo200. SulfasalazineSalazopyrineENPharmacia500. Viable organisms VivotifBernaBerna/Swissserum ofattenuatedSthypi strainTy21aBerna MIMS (2000) Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 18 BuprenorphineHClTemgesicSchering - Plough0.2. IsosorbidedinitrateHartsorbSiamBheasach5. Isordil Wyeth - Ayerst 5. IsoremRemedica5. Enteric coated tablet AspirinAspentRanbaxyUnichem300.Aspent - MRanbaxyUnichem60. EntrarinAsiamPharm300. Seferin - 5GeneralDrugHouse325. Seferin - 10GeneralDrugHouse650. V - AS ProgressLab300. BisacodylDulcolaxBoehringerIngelheim5. EmulaxBritishDispensary5. BisacodylGPO5.O CodergocrineHydergine FASNovartis 4.5.DiclofenacAmminacMacroPhar25. ArclonacCondrugs25,50. DemacOsotspa 25. Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 19O S P E 1) 2) 1. tight container (desiccant) salicylic acid aspirin Hard Gelatin Capsules Soft Gelatin Capsules Uncoated Tablets Coated Tablets Dry Powders and Granules Powders and Granules Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 20 Effervescent Tablets, Granules, and Powders Solutions, Elixirs, Syrups 2 Emulsions creaming Suspensions (particle size distribution) caking Tinctures Fluidextracts Sterile Liquids Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 21 Creams Ointments (bleeding) (consistency) Suppositories 2. 3 (expiration date) / 3. (controlled room temperature, 20-25 0C) (controlled room temperature) 23 0C 75% (cold temperature) (outer container) Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 22 15 0C 2 8 ( 10) 0C / paraldehyde Salicylic Acid Lotion BP ..2542 (ExpirationDate) / 06/2005302548 12/2006312549 Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 23 - Freezer 20 C 10 C (-4 F 14 F)- Cold 8 C (46 F) - Refrigerator (Cold) 2 C 8 C (36 F 46 F)- Cool 8 C 15 C (46 F 59 F)- Room temperature 25 C- Controlled room temperature 20 C 25 C (68 F 77 F)- Warm 30 C 40 C (86 F 104 F)- Excessive heat 40 C (104 F)- Protection from freezing - Protection from moisture 60%- 40 C (104 F) Chloramphenicol ear drop-- Chloramphenicol eye drop-- Hepatitis B vaccine (Engerix B)21C 2 , 37C 1 - Humulin 70/30 100 iu/ml,10 ml 15-30 C 1 Humulin N 100 iu/ml,10 ml15-30 C 1 Mixtard 30 HM penfill 100 iu/ml,3 ml 15-30 C 1 Tetanus Toxoid (TT) 0.5 ml18-25C 6 , 37C 6 TRCS- verorab (Rabies vaccine)18-25C 36 , 37C 1 ( : ) Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 241) (Exp. date Use before)- ( )- 3 - 5 - 2 - 1 - .. 1 2) - : 7 - :Fluimucil 1 1 ORS 1 240 ml (1 ) 24 . ()- EENT : 30 () (.) Amoxicillin60714 Augmentin60-7 Dicloxacillin60714 Distaclor6047 Erythromycin60714 ( : ) Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 25O S P E ....... ....... 1. 1.1. - - - - - - - - - - - - - - - - () - () 1.2 1.1 1.3 1.3.1 (1) 3 4 Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 26(2) 2 SMP 1.3.2 (1) (wheeze) 3-4 (whooping cough) (2) (3) (4) (5) (6) Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 27 // (7) / (8) 2. 2.1 1 5 1 2 3 4 3 5 5 30 3 2 Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 28 5 3 4 5 2-3 1-2 6 7 10 40-55 4 6 1 8 9 2.2 - - - - - - - Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 29 - - 4 - - - - - - - - - - 30 3 - / - - - - - - () - - - - (aerobic exercise) 30 3 - - ()Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 30- - - - - (aerobic exercise) 30 3 - - ( ) - -( ) - - - - - - () -( ) - - Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 31O S P E 1. 1.1 (1) (2) film coated tablet sustained release tablet regimen 2 (3) (4) (4.1) (4.2) (4.3) (4.4) (5) 2. 2.1 2.1.1 (1) Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 32- - - - (2) 2.1.2 4 2 15 paracetamol syrup (120 mg/5 mL) paracetamol 10 mg/kg/dose ( 10-15 mg/kg/dose) 15 = 15 x 10 = 150 mg/dose paracetamol syrup 120 mg/5 mL (150 mg/dose) / (120 mg/5 mL) = 6.25 mL/dose 1 5 mL paracetamol syrup 1 ( 6.25 ) 6 2.2 .. 2540 Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 33(1) (2) (3) (4) (side effect) () (adverse drugreaction) (5) (6) cloxacillin capsule (500 mg) 1 x 4 PO ac 20 - cloxacillin 500 20 - - 1 4 1 6 - - - 1. , 2. 3. 4. (,) 5. ( ) () - -...... ... -/ / -controlrelease - ( ) - -/ Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 34 -paracetamol 10-15mg/kg/dose -Amoxycillin20-50 mg/kg/day 1 =5ml1 =15ml 2 10 kg- Ibaimoxsyrup(Amoxycillin)250/5 ml 10 - Sarasyrup120/5 ml Ibaimoxsyrup 1kg50mg/day (max dose) 10 kg500mg/daydose 4 125mg Ibaimoxsyrup250/5 ml 4 2 Sarasyrup 1kg10mg/dose 10 kg100mg/dose 120/5 ml 120mg 5ml 100mg (5*100)/120=4.17ml O S P E Dry Syrup 2 1 - - - 1/2 - - - 72 - 2 Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 35Sodium thiosulfate - 1/2 2/3 - - - 2 - - - 1 - 24 Cholestyramine - 160-90 - - (3) syringe - syringe - household measurement syringe - syringe - - syringe -( .....) ... - () - / / () - - - Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 36 - - 1/2 - 2/3 - - - 7 14 / 1. 2. 3. 2 4. O S P E ....... ....... 1. ORS -( .....) -- (() / / ) - - - - - - / / - - Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 37 - 1 1 1 - 24 / - - 4 - ( (C.E.) . 1 5 4 4 ; ) - 3 2. (Sublingual tablets) 1. 2. 1 3. 5 3 4. 5 10 - Isosorbide dinitrate sublingualtablet (Sublingual) -( .....) ... - ()- / / () - - - Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 38- 1 - 5 2 1 5 3 3 - 5 1 / - Isosorbidedinitrate - - - - 3. - - - - - 12-14 4. (Eye drops) 150 () 1. 2. 3. () 4. Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 395. 6. 1 ! 7. ( 30 ) 8. ( ) - 1 1 1 1 5 - 2 5-10 10 - - - - - - - 1 - - - (Eye ointment) 1. 2. 3. 4. 5. 11/2 ! 6. Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 407. 8. 9. 21010 - - - - -( .....) ... - ()- / / () - - - / - - - - 30 - / - 2 5-10 10 - - - - Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 41- 1 () -chloramphenicol - - -contactlens -( .....) ... - ()- / / () - - - / - - - 1 - - - / - 2 10 10 - - - - - 1 () od= ,ol = , au = Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 42(Ear drops) 1. 2. 3. ! 4. 3-5 5. 6. 2-3 -( .....) ... - ()- / / () - - - - - 2-3 - - - 3-5 5. Metered Dose Inhaler 1. 3-4 ( ) 2. 3. () 3-41-2 2-3 ( ) Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 434. 1 5. 10 6. 7. 1-2 8. 9. 2 25 - - - - 2 - 1-4 - Accuhaler 1. 2. accuhaler 3. 4. ""5. 6. 7. Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 448. 10 9. "" 10. - - accuhaler - accuhaler Turbuhaler 1. 2. 3. () () 4. 5. 6. 7. 10 8. 1 9. 10. - - 2 - - 1-4 - 20 (doses) Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 45 (Inhalation) -( .....) ... - ()- / / ( ) - - - ( ) - - - - 1 - - - / - 30 2 - - 2 - 2 5 - 1-4 - - - * * Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 466. (Nasal spray) 1. () 2. ( ) 3. 4. 5. 2-36. (2) 7. 2 1 2 2 2 8. - - 2 - - (Nasalspray) -( .....) ... - ()- / / ( ) - - - ( ) - - - Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 47- - 2-3 - 2 - 2 1 - / - - - (Nasal drops) 1. () 2. 3. 4. 5. 6. 5 7. ( ) 8. - 3-5 - - (0.9% normal saline) 1. 0.9% 2. 5-10 0.5-1 3. 4. Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 487. (Rectalsuppositories) 1. 2. 3. 4. 5. 6. ( 15 ) 15-20 (Rectalsuppositories) Proctosedyl,Scheripoct N -( .....) ... - () - / / () - - - - - - - - 15 / 1. 2. 2 10 3. Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 494. 5. 6. 7. (Rectal enema) 1. 2. 3. 4. ( ) 5. 6. 2 - 3 15 - 30 8. (Vaginalsuppositories) . 1. 2. ( 1-2 ) 3. 4. 5. 15 7 Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 50. 1. 2. ( 1-2 ) 3. - - 4. 5. - - - 6. 15 (Vaginasuppositoies) Canesten -( .....) ... - () - / / () - - - - ( 1-2 ) - - - 15 / 1. ( ) 2. 3. 2 .. Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 519. (Oral contraceptive tablets)1. 21 1 21 1 (1) 5 ( ) 7 2-4 7 28 1 21 7 2. 2.1 1 2 14 2 2 7 2 14 7 3 7 2.2. 1 2.3. tetracyclines, penicillins, quinolones, cephalosporins metronidazole progestin 2.4. rifampicin enzyme inducer 4 rifampicin enzyme inducer Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 523. - 2-3 - - - - 2-3 1. ? 2. ? 3. ? (Oralcontraceptive) 21 28 -( .....) - - / / - / - / - - - ( 21 )- 21 21 7 28 - 10 - 1 Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 53- 7 7 2 / - 15 15 - 2-3 - 1 12 12 2 ( 12 ) 2 2 week 2 2 condom 1 week 2 week 3 2 ( 28 )- 28 21 7 - - 1 - 7 2 / - 15 15 - 2-3 - 1 12 12 2 ( 12 ) 2 2 week 2 2 condom 1 week Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 542 week 3 2 Postinor,Mardona -( .....) - - / - - ( levonorgestrel0.75 mg ) - - 72 - 12 / - - - 1 2 4 - , - - - - Primolut-N -( .....) - - - - -- - - 60 kg 1*3 pc 60 kg 1*2pcComprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 55-2-3 10-14 2-3 / - 14 21 28 - ,() *combinedpill 1*1 7 2*2 pc Primolute-N * 10. Insulin 1. 2. 3. () 4. (syringe) 5. 6. 7. 8. 9. 45-90 10. 11. - - 1 - - Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 56 -( .....) ... - ()- / / () - - - - - ()- - - - - - () - () - - -- 45-90 ( 45 90 ) - - / - 1 Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 57- 2-3 - ( ) - 11. - - - - - - - 10 - / - - - - - - 30 - - - 15 Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 58- 2 mg 30 4 mg 15 12 (3 ) - / - O S P E (narrow therapeutic drugs)warfarin, phenytoin, theophylline, digoxin Digoxin - digoxin / ( ) - digoxin () ( 12 ) 12 2 - () digoxin 2 digoxin Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 59Phenytoin - phenytoin.... .....( ) - phenytoin () - Phenytoin Phenytoin - phenytoin phenytoin phenytoin Theophylline - : Theophylline ( ---) ( )- Theophylline () Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 60 2 (shortness of breath) - theophylline () - theophylline Warfarin - : warfarin . ( )- warfarin () 12 2 - - warfarin Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 61 warfarin warfarin warfarin warfarin warfarin Methotrexate - : methotrexate ( ) - Methotrexate / ( ) 1 ( 12 ) 12 1 2 - methotrexate / - ( ) ( HIV) methotrexate Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 62 methotrexate Cyclophosphamide - : cyclophosphamide - cyclophosphamide () ( 12 ) 12 2 - / cyclophosphamide - 10 cyclophosphamide cyclophosphamide Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 63 Isoniazid - isoniazid

- isoniazid ( ) 1 2 () - isoniazid 6

- Isoniazid 1 Isoniazid Rifampin - rifampin (--) ( ) - rifampin ( ) 1 2 () Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 64- ( ) rifampin rifampin - rifampin rifampin rifampin rifampin rifampin Pyrazinamide - pyrazinamide - pyrazinamide () - pyrazinamide - pyrazinamide Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 65Ethambutol - : ethambutol - ethambutol ( ) ( 12 ) 12 2 - ethambutol - ethambutol 2 ethambutol ethambutol ( Sheet OSPE 48) - - - / -- - - - - / / Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 66Digoxin ( ....) ( )/ (druginteraction) / Digoxin( ) / Digxin.... mg.... ..../ () 12 12 2 - Digoxin , - Digoxin 2 , ,(), ,, ,,, () / / Digoxin Phenyltoin ( ....) ( ) / (druginteraction) / Phenyltoin( ) / Phenyltoin...mg.......... / () () Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 67- Phenyltoin,, - Phenytoin -,, , ,, () - Phenytoin, / / phenyltoin Warfarin ( ....) ( ) / (druginteraction) / Warfarin () / Warfarin...mg.......... / () 12 2 - Warfarin - - ,,, ,, () / / Warfarin Theophylline ( ....) ( ) / (druginteraction) / Theophylline () Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 68 / Theophylline...mg.......... / () - Theophylline ,,, - () ,,,,,, / / Thyophylline O S P E 1. 3 2. - - Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 69- 5 - - - - - - ( 49) - / - Triple check ( 2 ) - Alcohol 70% ( 2 ) - ( 2 ) - 5 ( 2 ) 2-3 1 4-5 0 - ( 2 ) - Alcohol70% () * () * paracetamol chlopheniramine Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 70O S P E 1. 2. (1) (2) ( ) (3) - (4) ( ) (5) ( ) (6) (7) (8) - : 2 2 1/2 () 3 1 2 2 12 - 1 - 1 - - - - - . - .. - ..... - .. Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 71- ( metered dose inhaler) - . ( dry powder inhaler turbuhaler, accuhaler) - - - 2- - - 2- 2 : 2 1 2 ..... : 2 10 7 Bisacodyl . 16 . . . 074 212586 12 .. 49 Dulcolax (Bisacodyl) 5 mg 20 1///1 -.. (1) (2) (3) Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 72Cloxacillin 1 x 4 PO ac & hs 6 . 16 . . . 074 212586 12 .. 49 Diclocin (Cloxacillin) 250 mg 20 1.///4 -.. - (1) 2 (2) . 16 . . . 074 212586 12 .. 47 Diclocin (Cloxacillin) 250 mg 20 1.///- 6.. - Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 73Paracetamol . 16 . . . 074 212586 12 .. 47 Para (Paracetamol) 500 mg 20 1-2.///- 4-6.. 8 (1) 8 (2) 5 paracetamol 2 6 5 18 . . . 074 212587 12 .. 47 Para (Paracetamol) 500 mg 50 2.///- 6 .. (1) 8 Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 74Chlorpheniramine . 16 . . . 074 212586 12 .. 47 CPM (Chlorpheniramine) 4 mg 20 1.///- 4-6.. (1) 6 (2) chlorpheniramine 4 mg . 16 . . . 074 212586 12 .. 47 CPM (Chlorpheniramine) 4 mg 20 1.///3 -.. (1) 6 (2) 7 (3) Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 75 O : chloral hydrate : chlorpheniramine,triprolidine, diphenhydramine dimenhydrinate, hydroxyzine, chlodiazepoxide, diazepam, codeine, morphine, tramadol, chlorpromazine, haloperidol, clonazepam, perphenazine,amitryptyline, phenobarbital O disulfiram-like reaction : metronidazole, tinidazole, chlorpropamide : aspirin, diclofenac, ibuprofen, indomethacin, mefenamic acid, naproxen, metformin, theophylline, tretinoin, prednisolone, dexamethasone, ketoconazole Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 76 2 : penicillin V, ampicillin, cloxacillin, didanosine, enteric-coated tablet : omeprazole, enteric-coated aspirin (Aspent), enteric coated diclofenac (Voltaren), bisacodyl (Dulcolax) tetracyclines fluoroquinolones 2 doxycycline minocycline : : () : 6 24 10 1 ergotamine tartrate : Cafergot , Avamigran 2 8 24 5 paracetamol500mg osteoarthritis 5 : Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 77 NSAIDs sulfonamides enteric-coated, sustained-release : : isosorbide dinitrate 8 glyceryl trinitrate (nitroglycerine) glyceryl trinitrate phototoxic photoallergic reaction: isotretinoin, chlorpropmazine, nalidixic acid doxycycline : phenazopyridine rifampicin ( anthraquinoneglycoside ) : 1. Pressurized Inhalation (Aerosol Inhalations) Metered dose inhalers : Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 782. : 3. -cream, gel, ointment : - liniments lotions: 4. : 5. : 6. - Effervescent powders : - Bulk powders : 7. - : - : - sustained-release, enteric-coated : Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 798. mixtures, syrup, suspension, emulsions : 1. 2. 3. / / 4. 5. 6. / / * Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 80O S P E 6: 1. 2. 1. 1.1 1.2 2. 2.1 2.2 2.3 1. - 140/90 130/80 - - 2. Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 81 22 2 (9 .. 47) pharyngitis paracetamol (Tylenol) 500 mg 2 4-6 amoxicillin (Ibiamox) 500 mg 1 3 -- (11 .. 47) maculopapular rash amoxicillin maculopapular rash amoxicillin roxithromycin chlorpheniramine amoxicillin maculopapular rash WHO criteria (possible) amoxicillin Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 82 1.1 1 ( ) 2. 1. 1.1 // 1.2 2. 2.1 HN HN AN 2.2/ () 2.3 -1 5 3. -3 24 12. -3 4- -() 2.4 () . co-trimoxazole 2.5 () 3. 3.1 3.2/, (Lot No.) S =Suspected product Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 83O =Other product I =Productinteraction ( ) 3.3 (route of administration) 500 mg/tablet, 1 tablet 3 times per day, per oral 3.4// 3.5// "Continue" 3.6ICD CODE ICD-CODE () 4.4.1 preferred termsincluded termsWHOAdverse ReactionTerminology ICDCODE 4.2// 4.3 4.4 OO O 1.Death() () () 2. Life-threatening( ) 3.Hospitalization-initial/prolonged() ( life-threatening, required intervention to prevent permanent impairment or damage) Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 844.Disability() 5.Congenitalanomaly() 6. Required intervention to prevent permanent impairment or damage ( ) (allergic bronchospasm) (blooddysplasia) (convulsion)4.5(dechallenge) (rechallenge) OO(Dechallenge) 1. (Definiteimprovement) 2. (No improvement) 3. (Unknown) O 1. 2. O (Rechallenge) 1. (Recurrence of symptoms) 2.(No recurrence) 3. (Unknown) O (no rechallenge performed) 4.6 (Outcome) Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 85 1. 2. 3. 4.- 5.- 6.-() 7. 5. 5.1 5.2 6. 6.1 ../ 43/1 6.2// 6.3/ / 6.4 / 7. 4 Certain() () (1) (2) (3) (4) Probable() ( ) (1) (2) Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 86(3) (4) Possible() () (1) (2) (3) Unlikely() ( ) (1) (2) Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 87 1. 1.1 () 2. 2.1 2.2 2.3 () 2.4 500 mg./tablet,1 tablet 3 times per day, per oral 2.5 // 2.6 "Continue" 2.7 3. 3.1 3.2 () 3.3 3.4 3.5 3.5.1 3.5.2 Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 884. () .. 5. 6. 1. 2. 4 Certain 1) ( ) 2) () 3) 4) 5) Probable 1) 2) () 3) 4) 5) Possible 1) 2) () 3) 4) Unlikely 1) 2) () 3) 4) Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 89O S P E 50-100 40-60 (metabolite) / 1.Pre-implantation period Blastocyst (2 ) All or none response 2.Embryonic period 2-8 3.Fetal period 9 5 Pregnancy CategoryA Pregnancy Category B PenicillinsPregnancy CategoryC Amitriptyline, Norfloxacin Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 90Pregnancy CategoryD Lithium Carbonate, Phenytoin ,Phenobarbital ,NortryptylinePregnancyCategory X Simvastatin , QuinineSulfate ,ProgynovaR , Oxytocin , Warfarin Diclofenac Pregnancy Category B 3 Pregnancy Category D Dexamethasone Pregnancy Category C 1 Pregnancy Category D O S P E 8: 1. 2. ( 1, 2, 3, 4 5)3. 4. Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 915. ( )6. 7. 1. 4 .. 2510 "" (1) (2) (3) (4)

(1) (2) (4) () () () 4(2) 2. ( 1, 2, 3, 4 5) Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 92 .. 2510 60 .. 2522 1 ( ) 2 ( ) 2 3 ( 60 ) 4 ( lysergic acid, glacial acetic acid ) 5 ( )3. 12 .. 2510 13 12 (1) (2) (3) (4) (5) 13 4. 37 .. 2522 3 (1) 3(2) 31 (3) Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 93(3) (4) 28 .. 2522 2 (1) 2 (2) 2 5. ( ) 8 .. 2510 75 73 (1) (2) (3) (4) (5) 79 6. . . ( ) 7. Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 94 ( 33).. 2545 . . 2510 () (8) (9) () (10) 6 (11) (12) 1. 2. ( Roaccutane ) 3. 4. 5. * () 1. P2 = Psychotropic Substance Schedule 2 ( 2 ) .Ex. Fentamine ,Midazolam,Ketamine 2. P3,P4 = Psychotropic Substance Schedule 3,4 ( 3,4 ) 1 Ex. Alprazolam,Lorazepam,Diazepam 3. N3 = Nacrotic Drug Schedule 3 ( 3 ) 1 Ex. codeine 4. S = Special control Drug ( ) 1 Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 955. D=Dangerous Drug () 1 6. NDD =Non Dangerous Drug ( ) 1,2 7. E-D = External use-Dangerous Drug ( ) D 8. E =External use Non Dangerous Drug ( ) NDD (Psychotropic Substances) .. 2518 . .. 2518 4 1 (Abuse) Cathinone, DET, DMHP, Etryptamine. Methcathinone, Mescaline, Mescaline derivatives, Mescaline analog, 4-Methylaminorex, Parahexyl, PCE, PHP , Psilocine, Psilocybine, TCP, Tetrahydrocannabinol 2 Amfepramone, Aminorex, Butorphanol, Brotizolam, Cathine, Ephedrine, Estazolam, Fencamfamin, Fenethyline, Flunitrazepam, Flurazepam, Haloxazolam, Ketamine, Loprazolam, Lormetazepam, Mazindol, Methylphenidate, Mesocarb, Midazolam, N-Ethylamphetamine, Nimetazepam, Nitrazepam, Pemoline, Phenylpropanolamine, Phencyclidine, Phendimetrazine, Phenthermine, Pipradol, Pseudoephedrine ( ), Quazepam, Secobarbitol, Temazepam, Triazolam, Zolpiden, Zopiclone, Zipeprol, Zaleplon Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 96 3 Amobarbital, Buprenorphine, Butalbital, Cyclobarbital, Glutethimide, Meprobamate, Pentazocine, Pentobarbital 4 Allobarbital, Alprazolam, Barbital, Benzophetamine, Bromazepam, Butobarbital, Camazepam, Chloral hydrate, Chlordiazepoxide, Chlophentermine, Clobazam, Clorazepate, Clorazepam, Clotermine, Clotiazepam, Cloxazolam, Diazepam, Delorazepam, Ethchlovynol, Ethinamate, Ethyllofazepate, Fenproporex, Fludiazepam, Halazepam, Inorganic bromide, Ketazolam, Lorazepam, Medazepam, Mefenorex, Methyprylon, Methylphenobarbital, Nordazepam, Oxazepam, Oxazolam, Perlapine, Phenobarbital, Pinazepam, Prazepam, Propylhexedrine, Pyrovalerone, Secbutabarbital, SPA, Tetrazepam, Tofisopam 2, 3 4 Midazolam 15 Pseudoehpedrine 120 , Phentermine 15 Diazepam 10 , Lorazepam 2 Alprazolam 1 3 4 1 2 3 4 (1) (2) (3) 3 30 90 Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 97 ( . .. 2518) 2 , , , 5 20 100,000 400,000 5 20 100,000 400,000 1 5 20,000 100,000 2 10 40,000 200,000 3 60,000 500,000 Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 98 3 4 , , 5 100,000 , , , 50,000 1 20,000 1 20,000 10,000 10,000 50,000 1. .. 2518 2. http//www.moph.go.th .. . . ( ) . . ( ) . . .. . .. .. . Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 99 .. . '.' . '.' ( ) ( ) . '. ' O S P E 7: 1. 2. 1. 1.1 1.2 1.3 1.4 1.5/ 1.6 Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 1001.1. 2 - - (1) - , , - - (2) - - (1) : : : : ? (2) : : (3) : : : : : Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 101(4) (5) : : : : : 1.2 1.3 1. HandbookofClinicalDrugData 2. BritishNationalFormulary (BNF) 3. DrugFactsandComparisons 4. DrugInformationHandbook 5. Medication TeachingManual:Theguidetopatientdruginformation6. Martindale: TheExtraPharmacopoeia 7. USP DI8. MIMS and MIMs Annual ( /) 9. Pharmacotherapy: A Pathophysiologic Approach 1.4 1.5 / 1. 2. 3. 4. 5.Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 102 2 1. 2. - - - 3. 4. 1.6 2 1. (Vancouver style) 1. ././ ./ :/ ;/.. / 1 (1) Gerald L. Mandell Mandell GL 6 (et al)7 ( editor(s) ed(s) ) In (2) () (3) ed (4) (5) (6) (7) 124-156 124-56 Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 103Ellaworth AJ. Skin disorders. In: Koda-Kimble MA and Young LY. eds. Applied Therapeutics: The Clinical Use of Drugs. 7thed. Philadelphia: Lippincott Williams and Wilkins; 2001:36-1 to 36-24. , , . . : ; 2543. 2. . /././ ( / ); : / 1 (1) Gerald L. Mandell Mandell GL (comma) 6 (et al)7 (2) [ ] (3) Medline (4) / () (5) (6) 124-156 124-56 Boguniewicz M. Adverse reactions to antibiotics. Drug Safety.1995 Jun 1;13(5):273-80. 3. Internet Electronic sources 3.1 E-Journal././ /[serial online] ( );volume number(issue number):[]./ Available from:/ URL address./Accessed ,,/ . / 1 Morse SS. Factors in the emergence of infectious disease. Emerg Infect Dis [serial online] 1995 Jan-Mar;1(1):[24 screens]. Available from: URL:http://www/cdc/gov/ncidoc/EID/eid.htm. Accessed December 25, 1999. Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 1043.2 Internet ././();[]./ Available at:/ URL address./Accessed ,,/ . / 1 Hoffman DL. St John's Wort. 1995;[4 screens]. Available at: URL:http://www.healthy.net/library/books/hoffman/materiamedica/stjohns.htm. Accessed July 16, 1998. 2. - (Harvard style) (Parkin et al., 1996) ( , 2543) - 1. ,/ ,/ ,/ ,/,/,. / 1 (1) (Author) (comma) Gerald L. Mandell Mandell, G.L. 2 & 3 & ( (ed) (eds) 2 ) (Title) (2) (3) () (4) 1 edn. (5) (6) (7) Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 105Berkman, R.I. 1994, Find & Fast: How to Uncover Expert Information on any Subject, HarperPerennial, New York, pp.42-59. Mayer, L.A., 2000, Skin tests, In vitro tests In Allergic in primary care, 2nd edn, eds. L.C. Attman, J.W. Becker, P.V. Williums. WB Saunders Company, Philadelphia, pp 37-47.2. ,/ ,/,/,/ ,/ ,. / 1 (1) (Author) (comma) 2 & (2) (3) (___) (4) (5) (6) (7) Huffman, L. M. 1996, Processing whey protein for use us a food ingredient, Food Technology, vol.50, no.2,pp.49-52. 3. Internet Electronic sources / . ,( ),/ ,/ ,/ Available at:/address. Weibel, S. 1995, Metadata : the foundations of resource description, D-lib Magazine, [Online]Available at: http://www.dlib.org/dlib/July95/07weibel.html Comprehensive Pharmacy Review OSPE Pharmacy Rx24 Khon Kaen University 106 1. (Drug Identification) 2.(Availability) 3. (Dosage and Administration) 4. (Therapeutic use/Efficacy) 5. (ADR/Side effect) 6. (Drug/food interaction) 7.Pharmacokinetics 8.Toxicity 9. 10.Compactibility/Stability 1.Handbook of Clinical Drug Data - 2. Drug Information Handbook - A Z 3.Drug Fact andcomparison - 4.Martindales the extra Pharmacopoeia - Drug Fact and Comparison 5.MIMs and MIMs annual - Indication, Dosage, Precaution, packaging 6. - 7.. Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 107 OSPE (Objective Structured Pharmaceutical Examination) OSPE 1. 2. 3. OSPE 4. - OSPE (Objection Structured Pharmaceutical Examination) station - 30 station () 5 25 3 - 1 10 4 - 100 OSPE 80 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 108 OSPE Item 1 OSPE XXXXX ..2545 ()3 filtrate : 1..; 1.. ( ) 3. :ring stand 1, filter funnel 1, beaker 1, flask 1, graduated cylinder 1, beaker dropper; filter paper 2 plaited filter, plain filter / peppermint oil, talc () ; .. --------------------------------------------------------------------------------------------------------------------------------- Peppermint Water (10 ) --------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------- - plaited filter (2 ; plain filter 0 ) - filter funnel stand (2 ; stand funnel flask cylinder 0 ) - flask filtrate (1 ; beaker 0 ) -rinse ( 2 ; rinse 0 ) - funnel stirrer (1 ; stirrer 0 ) - funnel oil (2 ; 0 ) : --------------------------------------------------------------------------------------------------------------------------------- : OSPE Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 109OSPE Item 2 OSPE XXXXX ..2545 ()1, 4, 5 : 1..; -.. 3. :- / ; .. --------------------------------------------------------------------------------------------------------------------------------- : : " proctosidyl/ " : " 1" : (10 ) --------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------- - 1 " "(2 ; 0 ) -: 1 2-3 ( 3 ; 1 ; 2 ) - (2 ; 0 ) - (3 ; 0 ) - (1 ) -: (2 ) --------------------------------------------------------------------------------------------------------------------------------- Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 110 OSPE Item 3 OSPE XXXXX ..2545 ()3, 5 : 1..; -.. 3. : / 1 ; .. --------------------------------------------------------------------------------------------------------------------------------- .. 5 RxAmpicillin Dry Syrup # 1 Sig:Tsp iq.i.d ac & h.s. Ampicillin Dry syrup --------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------- - (2 ) : : 1 4 - (1 ) - (7 ) (2 ) (3 ) (2 ) --------------------------------------------------------------------------------------------------------------------------------- Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 111OSPE Item 4 OSPE ..2545.. () 7 .. : 1..; -.. 3. /-.. :drug information handbook TIMS / - 1.. Glyburide -------------------------------------------------------------------------------------------------------------------------------- TIMS drug information handbook synonyms = Glybenclamide TIMS local made.. BenclaminCytagon Debtan DiabeedolDiabenol Diclanil Diabelet GlibeGlibesyn GlybeticGlybic Gluconil Gluzo Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 112OSPE Item 5 OSPE ..2545.. () 5 .. : 1..; -.. 3. /-.. : meterdose inhaler . / - 2.. 1. Rx Salbutamol MDI1 puffprn #1 .MD. -------------------------------------------------------------------------------------------------------------------------------- 1.) .. 2.) .. 3.) . 4.) 3-4 1-2 .. 5.) 1 6.) 7.) 8.) Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 113 1. 70% alcohol 40 ml 7.5 ml 70% alcohol 32.5 ml -70% alcohol 32.5 ml Cylinder 50 ml Beaker 1 - 7.5 ml Cylinder 10 ml Beaker 1 - Cylinder 50 ml- Beaker 1 - 40 ml 2.pt pt Digoxin Digoxin 2 pt pt - - - - - Digoxin - - - - Digoxin 3.pt 2 prednisolone 5 mg 20 betamethasone cream1 - - OSPE 2546/1 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 114- - - - - - - - - 2 - - - - 4. paracet 500 mg 100 5. Prednisolone Diazepam 60 ml 6. 5-FU 7. Calcium form 8. Vanilline base 9 9. Calamine powder Vanilline base Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 11510. Gynecon Ventolin MOM 11. Dx 12. Ibilex dry syrup 13. Ilosone dry syrup 14. Actifed 5 Tylinol5 15. Label Lanoxin 30 Furosemide 30 Paracetamol 16. refill 3 Enaril5 mg30 Fluimucil100 mg8 Glybenclamide5 mg 30 Rx Enaril20 mg30 Fluimucil200 mg9 Glybenclamide5 mg 60 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 11617. Doxycycline 100 mg auxillary label 18. Paracetamol tablet Paracetamol syrup Prednisolone cream Cloxacillin 60 ml capsule 19. Antacil TabletExp 03/44 Aspirin Tablet Label DisentoExp. 09/45 ActifedMfd 11/45 20. Voltaren SR Romilar (Dextromethorphan) 21. Rx Chloramphenicol eye drop I OD2 x 4 22. Clotrimazole 1x6 tab hs 23. Sara syrup ORS 240 ml Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 11724. Wax technical term-burner -water bath -tripod -wire gauze -stirring rod -casserole 25. Set Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 118 1. Paracetamol 500 mg 100 2. Ventolin( Evohaler) 3. (Filtrate) 4. Talcum 15 ml 5. Folic acid 5 (0.8 mg/day) 6. warfarin 7. CPM4 mg Lot No. 210100 Mfd2-03-98 Exp.2-03-03 8. Diazepam Phenobarb Codeine OSPE 2546/2 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 1199. 2 Phenylbutazone () Diclofenac gel () 10. CPM Vitamin C HCTZ Furosemide 11. HCTZ() 1 2 ASA () 12. 13. Mucillin1x1hs2 Proctosedyl1x1hs2 14. Rx Cimetidine 400 mg1x3 pc30 Rx Cimetidine 200 mg20 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 12015. Rx Chloramphenicol eye drop 2 4 . 16. ORS Brown mixture Calamine lotion Voltaren 25 mg 17. emulsion (creaming) paracetamol syrup (precipitation) paracetamol tablet 2 (lamination) 18. 70% alcohol 95% alcohol 30 ml. 19. Vanilline cream 9.0 g 20. Cream base Sulfur powder 1 g 21. Lomotil Diazepam Prednisolone cream 60 ml 22. Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 12123. Anna 28 24. CPM1x330 25. Amoxicillin 250 mg/ml1 x3 pc 7 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 122 1. Inhalation 2. 3. 4. 5. Dose 6. 7. 8. 9. 10. 11. Syrup 12. Chlorpheniramine Maleate 13. 14. 15. 16. Isotretinoin 17. 18. Warfarin 19. Methotrexate 20. 21. 22. OSPE 2547/1 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 123 1. 2. NaCl 3 g.3. NaCl 3 g 60 ml 4. Ketoconazole Candidasis 3 5.Cream base Clindamycin 6. Calibrate 0.5 ml 7. Terco-C 8. Theophylline SR ADR 9. Evohaler10. 11. 3 Loperamide 12. 3 kg Para 13. CPM 100 14. Cream base Vanillin cream 9.5 g 15. Cream base Calamine powder16. Nitroglycerine 17. 18. Cream Gel 19. Technical term suppository effervescent tablet soft gelatin capsule mixture lozenge OSPE 2548/1 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 124 25 14 ( ) 11 Part 1 14 (- ) ... OSPE (0) 1 : MDI ( ) Salbutamol1pufftid : .. : ... (: ) .... Salbutamol 1 3 -- 1. 2. 3. 4. 5. 1 6. 10 7. 8. : : : () : OSPE 2548/3Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 125: MDI 2 : 28 ( 28 ) : .. : .... / / / ( antibiotic) () : // 24 // : .. 28 28 21 7 .. : : 1 15 2-3 : : ( .... 1 .... 1 .... 2 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 126 3 : vanishing cream Calamine powder1g Vanishing cream add to10g : digital 1 , , Spatula 2 , 2 1 : 1. Cream 10 -1 =9 2. 3. ? 4. Tare 0.000 5. Stainless spatula 2 1 Vanishing cream . triple check 6. Tare10.000off : Vanishing cream cream - spatula 2 3 spatula spatula spatula Tare Triple Check Self-conquest is the greats of victory. 4( 3) : calamine cream : 1 , calamine powder 1 , slab & spatula, mineral oil, glycerin :Set slap & spatula ( spatula slab ) Calamine powder (1) (2) slab (3) = (triple check) Spatula ( ) Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 127 Glycerin 3-4 calamine powder Spatula 1-2 Spatula vanishing cream Vanishing cream slab spatula Vanishing cream geometric dilution Spatula Spatula cream Vanishing cream o/w (4 vanishing cream water phase oil phase) Glycerin w/o mineral oil levigating agentTriple check 5 : : 1 ( Primolut-N) 2 zip : .... ( // ? ) : 45 / 3 15 ( 7) : ( 2-3 ) 1 2 2-3 : ( ..) 14 (14 12 7-8-9-10-11-12-13 14 2-3 ) 14 21 28 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 128 6 : lipid profile LDL Total cholesterol210 Triglyceride180 HDL45 : lab : lab : ... : LDL : lab : ( TC = LDL+HDL+VLDL VLDL = TG/5 LDL = 129 : : LDL 100 Triglyceride 150 cholesterol 200 : ... Triglyceride () : fibrate Gemfibrozil Triglyceride ( ) : : : Cholesterol ( Steroid ) : .. 7 Calibrate : calibrate dropper( 0.4 ml ) : , , dropper Cylinder 5, 10 ml 10 ... ... 2ml ...... 0.4ml ...... i. Cylinder 5 ml ii. 2 ml 4 Cylinder 2 ml Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 129iii. Dropper .. iv. Cylinder 2 ml cylinder v. ( check ) vi. vii........Net 10 8 9: ,, ACEI (Enalapril) ( ) 9( : 9( Dextromethorphan 13 ( Dextromethorphan bradykinin ) 9 99 1 92Phentermine 2 ( MIMs ) 9 MIMs 9( 10 Paracetamol tablet 100 Paracetamol CPM Triple Check Alc 5 Check Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 130 11 KI 2 % 9 1 , Digital, KI, +,100ml KI 2g 50ml KI(502)/100 = 1g (?) 12 KI ( 31) 9 Cylinder, Stirring rod, 9 KI 9 2/3 ( ) Cylinder 9 Solution Cylinder rins 13 9 9 , 9: Steven Johnson Syndrome, 9 Bractrim 910 14 () 9 9 Nifedipin SR ( : ) 9 ASA 1 3 (: 1 ) 9 10 11 3 :MIMs,Druginformation,Martindale,USP: Tablet, capsule(Soft or Hard), Lozenge, Suspension, Emulsion,pills : , , , : , (NSAIDs),(Cimetidine) :Antibiotic dry syrup, By ,,(), (RSU) Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 131 1. -Paracetamol 10 -lomotil -lorazepam -Enalapril -prednisolone cream 2. Paracetamol 100 3.Amoxy Dry syrup Indocid capsule capsule 4. Oxymet 5. KCl % 6. KCl Solution 30 ml 7. 95% alcohol 70% alcohol 8. 70% alcohol 95% alcohol 30 ml 9. Dose Drug information 10. Isotretrinoin 1 11. Theophylline 3 12. vanishing cream 13. Calamine cream 14. paracet syrup Dropper OSPE 2549/1 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 13215. - -Norflox 400 mg 200 mg -Buscopan plus Buscopan 16. Rx -Diclofenac 100 mgx 2 10 -Antacid1x320 17. nitroglycerine 1 - -mg - - - 18. Isodril 19. 20. Mims 21. -Acetylcysteine -calamine lotion -nifedipine soft capsule 22. Martindale 23. Bactrim- Paracet 24. -Loperamide -Enalapril -Brown mixt180 ml -Diazepam Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 133 1 2 5 1. 100 Suppositories Vaginal Tablet 2 2.ENO Effervescent Powder 3. SARGITA Lozenges 4. Mixture5. vial Dry powder for injection 3 - MDI NTG 4 - Diazepam- atarax 5 DIS - - Dose / regimen Interferon 2B - 2 -Druginformation Handbook Injection Drug - Vancouver 4-5 . 6 7 Aliquat - - Tetracyclin 2 % 25 ml Tetracyclin 250 mg - 2 OSPE 2549/3 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 134 8 tetracycline Tetracyclin 25 ml2 % - Tetracycline - - - - - - Tetracycline 9 - - 16 - 32 - 16 - 16 - - 28 - 64 10 - - - - - - 8 11 - - - regimen -Amoxy 20 mg/kgq 8 hr amoxy 125mg/5ml - --- Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 135 12 2 13 . 14 15slap + spatula- glycerin/ mineral oil . 16 - 90 - + - - - 17/ -- - - - atorvastatin - 18 1.Marvilon282.Doxycyclin - - . 19DM Hypoglycemia Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 136 20 DIS Remington Polibase 3 1.Remington 2. Mims 3. 21 . AST30 (0-35) ALT.() AntiHAC negative AntiHBS negative AntiHCS negative - - - - - ( ) 22 23- - - Cystitis BPH 26 - - 10 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 137 24 A -ORS 1 B-ambroxal 1 10 C-Bromhexine 1 10 D -Disento 1 4 E-Paracetamol 1 10 B C D E A E ( ) 25 - MDI 26 - 2 - (+)(3).. 1 2 3 Amoxy+K.clavulonate 500 mgq 8 hr pc#20 Chloramphenicol eye drop O.U#1 -Amoxy 250-Amoxy -Amoxy -Chloram - Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 13827 28 - 1 - BMI --- - Phentermine - P2 29 . .. .. // .. ... . . . . 30 . .. 2-3 1.Roxithromycin 150 mg 2.Actifed 30 A. 31 - - 5 1. 1 60 2.Phenylbutazone 3.Lomatil Dramamine 4.Prednisolone Cream 5.Dexamethasone 1 + 2+ 3 3+ 4+ 5+ By 127 CMU Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 139 By P Phung 1Advilgeneric martindale,mims drug information handbook MIMS. MIMS Thai Drug Information ASFH Generic Name Trade Name MIMS martindalegeneric ibuprofenmims ................................................................... Generic Name.......................... .............................Edition... ............................. Trade Name.......................... 1. .............................Edition... 2. .............................. 2 Isosorbide Dinitrate (Isodil) SL 30 prn. SL = Sublingual 1. ............. 2. ISDN mg 3. 1 5 1 3 2 . 3 ex 3 Amoxycillin (125 mg/5mL) 60 mL 6 15 ( 25 mg/kg/d) mL 4 Chlorhexidine solution 1 %w/v 30 mL Chlorhexidine Stock solution 10 % w/v Chlorhexidine Stock solution mL ExN1V1=N2V2 10 x V1=1 x 30 V1=3ml OSPE 2550/1 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 140 5 technique 1. Chlorhexidine 10% --- --- ---- 2. Cylinder 10 ml 3 ml. beaker Cylinder 3. 3 ml beaker 50 ml 30 ml beaker 4. H2O x 27 = 20 ml Cylinder 25 ml 5. beaker ---- stirring rod. 6. Cylinder 30 ml ( 50 ml.) H2O 30 ml. ( rinse beaker ) 7. beaker stirring rod --- 6 Paracetamol 500 mg # 90 1. 2. 3. ( 3 ) 4. 5 5. check 7 Vanishing Cream RxSulfur0.5g. ,Cream base qs.5g. Cream - + & label - , tare, , tare ( ) - Stirring rod spatula Cream cream - ** tare * ....................... Cream ................................... 8 Cream Sulfur + glycerin Mineral oil Cream, ointment Slab Spatula Pulverization by intervention interventing agent cream base - Vanishing Cream Cream base O/W glycerin - slab glycerin smooth paste- cream slab geometric dilution Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 141 9 (Codeine 100mg + Phentoloxamine 3 ... mg )# 30 codeine 3 .. Side effect1. 2............. 10 Carbopol Hydrogel a.Carbopol0.5 %w/w b.Purified water q.s. ad100 mL Mf.t.30 mL Carbopol ( ) carbopol 30 g gel 1. carbopol beaker + stirring rod Carbopol carbopol ( )2. 30 ml carbopol carbopol product ------------------------------ -------------------------- 11 triethanolamine (TEA) glycerin carbopol form gel technique ceutic - TEA 2-3 carbopol gel - PH ** PH paper gel stirring rod check technique gel carbopol form gel pH 12 Vitamin C 100 mg 10Sara 10 AmbroxalMebendazole 500 mg 1 Actifed 10 1.Actifed 10 - pseudoephedrine 2.Victamin C 10 - 3.Paracetamol 500 mg 10 - 4. Ambroxol- 5. mebendazole 500 mg 1 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 142 13 ( step ) 1. ---- ----- 2. 3. - --- Steroid 2 agonist - ----- normal flora 4. 14 c.Brown mixture 240 mL3 d.Lomotil e.Phenylbutazone f.Alprazolam g.Amitriptyline 1.Lomotil = Diphenoxylate HCl + atropine sulfate - 3 ... 2.Alprazolam - 4 3.Pseudoephedrine 60 mg - 2 pseudo 4.brown mixture 5.Amitriptyline 15 ---- 1. ---- 2. ---- 3. ---- + Amoxy 4. ---- Amoxy 5. 6. Case Guide Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 143 16 glibenclamide 10 Lab Lab FBS = 200mg/dL. HbA1c= 8 % 1. ---- 2. Lab 3. -FBS < 120 mg/dL.&HbA1c < 7% - - FBS HbA1c FBS HbA1c Hemoglobin () 3 FBS 1-2 HbA1c - + 17 , side effect () . . HN 12345 Cafergot (Ergotamine 1 mg + caffeine 100 mg) #10s Sig 2 tabsstat & 1 tabq hr. PRN Flunarizine 25 mg.# 10s Sig 1 cap tid.hs --- Migraine 2 1.Cafergot 10 migraine 2 1 6 10 Caffeine 2.Flunarizine 25 mg ... 18 norfloxacin domperidone + Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 144 19 Metformin# 30s 1 x 1 pc Aspirin60 mg# 30s 2 x 3pc Simvastatin 10 mg # 30s 1 x 1Q.A.M. 1.Metformin Metformin 500 mg. 2.Aspirin Aspirin 60 mg. 1 x 1 pc. 3.Simvastatin 1 x 1 Q.A.M. Simvastatin 10 mg. 1 x 1 hs. 20 refill Fluoxetine1 x 1 Diazepam 1 x 1hs. ... Diazepam 4 Fluoxetine side effect Diazepam 21 ---- - --- - ----- - ---- - ------ - ------ - ----- - AIDS ----- - ??? Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 145 22 Erythromycin 2-3 Theophylline Budesonide 1 puff tid Theophylline erythromycin enz. inhibitor Theophylline Theophylline narrow therapeutic side effect S/E Caffeine roxithromycin Cimetidine Theophilline inducer 23 Sulfadiazine yellow ointment yellow ointment martindel , Phamaceuticsl Excipient 3 yellow ointment 24 Dosage form ( technical term) 1. ( sugar coated film coated ) Coated Tablets 2. 5 Effervescent tablets 3. Mixtures 4. Lozenges 5. Emulsions Dosage form S 25 Diclofenac SR(100 mg) 1 Antacid diclofenac sustained released antacid - ....................... - - Antacid gel Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 146 BY Pandanus idin Rx21 KKU 1. 2. dosage form technical term A. Sugar coated tablet B. Effervescent tablet C. Mixture D. Lozenge E. Emulsion 3. generic name Advil 3 - Drug Information International index generic name Advil Ibuprofen - MIMS index trade name ibuprofen ** , , ** 4. isosorbide SL 1 tab prn - - (isosorbide) ( ) - 1. 2. 1 3. 4. 1 2 5 3 5. 6. 5. Actifed Vitamin C Ambroxol Sara Benda 500 OSPE 2550/ 1 (Version 2) Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 1476. .. 15 kg amoxicillin 25 mg/kg/day 7 amoxicillinsyrup 125 mg/5 ml 60 ml - = 25 mg x 15 kg = 375 mg/day - = (375 mg/day x 5 ml)/125 mg = 15 ml/day - dose = 15 ml/3 dose = 5 ml = 1 tsp - 7 = 15 ml/day x 7 day = 105 ml - 2 - () - .. ......... - amoxicillin syrup - 125 mg/5 ml - 2 - - 1 3 - - - - 14 7. 8. Rx Chlorhexidine gluconate 1.0 % w/v M.Ft Solution 30 ml 10% Chlorhexidine stock solution Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 148 chlorhexidine 1% 10 30 ml 10% chlorhexidine stock solution 1 3 ml 9 27 ml 9. Chlorhexidine gluconate solution 30 ml 1. 10% chlorhexidine stock solution 3 ml cylinder 5 ml 2. 3/4 = 3/4 x 27 ml = 20.25 ml 3. 21 ml cylinder 25 ml 4. 10% chlorhexidine stock solution 3 ml beaker 50 ml 5. 21 ml beaker 10% chlorhexidine stock solution 6. stirring rod 7. cylinder 50 ml 8. 30 ml 9. beaker 50 ml 10. paracetamol 500 mg 90 1. 2. 3. ** 4. 5. ** 6. 7. 8. 5 9. 10. 11. 12. ** 13. 14. ** triple check** 11. Rx Sulfur 0.5 g Vanishing base qs.ad. 5.0 g base 1. base = 5.0 0.5 = 4.5 g 2. label vanishing base 4.5 g 3. 4. 5. 6. 7. tare 0.000 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 1498. vanishing base** 9. vanishing base ** spatula (stainless) 10. vanishing base stirring rod 4.5 g 11. vanishing base** 12. vanishing base 13. tare 0.000 14. ** triple check** 12. sulfur base 1. slab + spatula (stainless) 2. sulphur slab 3. slab lock slab 4. spatula (stainless) sulphur (trituration) 5. levigating agent base (vanishing base o/w glycerin) 6. glycerin sulphur paste (levigation) 7. vanishing base slab 8. vanishing base paste (geometric dilution) 9. sulphur slab 13. 14. Rx Codeine phosphate 11 mg Phenyltoloxamine 3.67 mg (both bound to a resin) in 5 ml syrup 3 15. Rx Carbopol 0.5 % Purified water qs.ad 100 ml Hydrogel qs to 30 ml hydrogel 30 ml purified water qs.ad 100 ml = hydrogel 100 ml hydrogel 100 ml carbopol 0.5 ml hydrogel 30 ml carbopol = (0.5 ml x 30 ml)/100 ml = 0.15 ml hydrogel 30 ml = 30 0.15 = 29.85 ml hydrogel 30 ml 1. + 2. 29.85 ml cylinder 50 ml 3. carbopol 4. hydrogel 5. hydrogel station Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 15016. hydrogel station 15 pH gel gel gel neutralizing agent triethanolamine gel gel pH hydrogel pH paper 4 stirring rod gel paper paper paper standard 4 paper paper standard pH standard 17. diclofenac SR 100 mg antacid tablet diclofenac SR 100 mg antacid tablet Diclofenac SR 100 mg sustain released 25, 50 75 mg Antacid tablet antacid suspension 18. /// 1. 2. 3. 4. 5. 6. () Rx Budesonide 1 puff BID Salbutamol 1 puff prn 7. () Budesonide 1 2 - Salbutamol 1 8. 9. ( ) Budesonide steroid 10. () Budesonide 11. () Clotrimazole vaginal tablet 19. 20. Phenylbutazone X Brown mixture X Lomotil 3 X Amitriptyline X Alprazolam 4 / Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 15121. Rx Silver sulfadiazine Yellow ointment yellow ointment - Remington index yellow ointment - yellow ointment yellow ointment ** , , ** 22. /// 1. 2. 3. 4. 2 5. 6. - ampi 7. 8. - amoxi 9. () 10. 10 11. ( ) ampicillin penicillin amoxicillin penicillin 12. () amoxicillin penicillin 13. () Chlorpheniramine syrup 23. 1. Norfloxacin 1x3 - () - ......... - norfloxacin - 400 mg - ........ - - 1 3 - - 1 - Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 1522. Domperidone 1x3 - () - ......... - domperidone - 10 mg - ........ - - 1 3 - 15-30 24. 60 DM type 2 lab glibenclamide 5 mg 10 LAB FBS 200 HbA1c 9% 1. 2. 3. 4. 5. 10 6. ( lab) 2 - FBS FBS 126 FBS 200 FBS 90-130 - HbA1c HbA1c 9% HbA1c< 7% 7. () glibenclamide 5 mg 10 ( ) 8. () - - - - - 8 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 15325. Rx Cafergot 2 tab then 1 tab prn Flunarizine 2x1 hs 1. Cafergot 2 tab then 1 tab prn - Cafergot - - 2 1 - 6 / 10 / - - 2. Flunarizine 2x1 hs - Flunarizine - - 2 1 - - 26. 27. ASA 60 mg 2x3 PCASA 60 mg 1x1 PC Glipizide 1x1 AC OD Glipizide 5 mg 1x1 AC OD Simvastatin 10 mg 1x1 QAM Simvastatin 10 mg 1x1 HS Metformin 1x3 PC Metformin 500 mg 1x3 PC 28. Fluoxetine Diazepam 1. 2. () 3. 4. 5. 6. 7. () 2 - fluoxetine - diazepam 4 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 154- fluoxetine 8. () 29. /// 1. 2. 3. 4. 5. 5 6. 7. 8. 9. 10. () 30. penicillin (anaphylaxis) erythromycin theophylline 1. 2. ...().... 3. () erythromycin theophylline 2 drug interaction significant 2, onset delayed, severity moderate documentation established serum level theophylline theophylline therapeutic index theophylline level therapeutic level toxicity theophylline erythromycin level MIC 4. 2 monitor theophylline level erythromycin antibiotic erythromycin antibiotic 5. roxithromycin penicillin macrolide (erythromycin, clarithromycin, azithromycin,dirthromycin, troleandomycin DI theophylline ) Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 155 1. Calcium (effervescent) 2. 28 3. Lomotil Carbamazepin Lora CodeineAmitryptiline 4. talcum () 5. talcum dusting powder 6. 7. CPM 20 + 8. digoxin 9. SARA, Acetyl Cystein, Antacin ,Actifed ,ORS10. Gel, suspension, vaginal tablet, syrup, solf gelatin capsule 11. Isotetranoin 12. Ofloxacin Alum milk Sucralfate 13. tegaserod MIMS ? 14. 15. Erythromycin 16. Lab lipid profile 17. 18. drop 19. Glipizide Chorlestyramine 20. Metronidazole Suspension 21. Smoot paste 22. Metronidazole suspension23. Carfergot + Flunarizine24. Aspirin 25. Phentermine OSPE 2550/2 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 156 1 2 / 1. 3 4 (Ans.. ) 2.HCTZ (Ans 1*1 1*2) 3. vit B HCTZ 4.dose enalapril (Ans.. dose 20 mg 5 mg) 3 + 4 .2 Disento Antacin Mebendazole 500 mg 1 Tiffy Ans ambroxol, benda 500 ,Disento , Antacin , .2 Antacil ( = ) 5 Case 2 TB pyrazinamide . - ->> + enzyme alcohol , B, . toxic paracetamol, pyrazinamide enzyme 6 Omeprazole Omprazole MUPS ,, 7 metronidazol 1 fl.oz 3 8 metronidazole + syrup wetting agent OSPE 2551/1 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 157Ans.. metro () . 100 mg/tps 5 ml (1 teaspoon) metro 100 mg 30 ml (1 flu.oz ) metro (30 100) / 5 = 600 mg metro 200 mg 1 metro 600 mg (1 600) / 200 = 3 9 syrup metronidazole suspensions Ans.. 1 2 propylene glycol 3 cylinder 25 ml 4 14 ml 5 5 10 2 10 dose + + Ans.. 1 3/4 12 ml ( approximate volume 30 - 14 = 16 3/4 16 12 ) 2 cylinder 25 ml 3 9 suspension cylinder 50 ml beaker cylinder 4 rins 5 30 ml 5 10 2 12 theophyline + side effect + 13 14 Case 15 hydrophilic base 16 iodine + hydrophilic base lavegating agent 2 purified water mineral oil Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 158 17 Codeine + GG 18 phenytoin 3 19 Hog gum synnonym + + ..... ...... ...... ...... 2 Remington Goodmam Grilman ( Remington )Ans.. Hog gum Remington tragacant USP acacia 20 Humulin N 2 Drug informationHandbooks MIMs Ans.. Drug infor Humulin 70/30 MIMs Advil drug infor H Humulin 70/30 dosage form 775 !!!! MIMs 5 95 MIMs MIMs ..... 21 Vit B1-6-12 30 + 22 Case Aspirin Aspirin 13 2-3 - - >> Ans .. ASPIRIN aspirin 13 para 40 37 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 159 ...... aspirin aspirin bleeding case -6- ... 23 Dosage form Lozenges + gels + vaginal suppositories + suspension +soft gelatin capsules Ans.. Dosage form 1. Lozenges ---> Mybacin2. Gels 3. suppository tablets vaginal suppositories tablets 4. Suspensions -- > calamine lotion 5. soft Gelatin capsule 24 Actifed Roxithromycin 25 30 + phentamine . 2 + side effect phentamine ( phentamine P2 P3 5 T_T) 26 Case HCTZ Enalapril 170/100 - - - >>. 27 Rx Marvilon 1*1 hs Amoxicillin 1*3 pc . Ans.. Drug interaction ....Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 160 ( ) (-/\-) 1. drug interaction () 2. 3. 4.( ) (5555)5.( ) .... 4 3 (34) ...... 28 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 161 1. 2. .Mucosolvan .Ibuprofen ( 4 ) . ( 4 ) . 180 ml . 3. . 2 Antacid Norfloxacin - Antacid impairabsorption 2 . Norfloxacin shigellaspp. 400 mg 1x2 pc 3 4. ergotamine+caffeine Funarizine . 16 . . . 074 212586 10 51 ..... Cafergot (ergotamine 1 mg + caffeine 100 mg) 2///1 -.. ...... 6 / 10 / . 16 . . . 074 212586 10 51 ..... (Funarizine) 2///1 -.. . OSPE 2551/2 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 1625. lab . 3 lab ASTALT 100 ( 3 3 ) HBsAgpositive- labASTALT cell lab Hep. B b 6 case 6. 55 ca 3 calcium carbonate effervescent tablet , tablet capsules - tablet 1-2 - 1 1 - capsule - calcium ca ( ) 7. 8. 6 1 () - dyspepsia GERD dyspepsia dyspepsia ( ) GERD PPI H2RA 2 4-6 domperidone Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 1639. Gel base A 0.3 g Gel base qsto 10 g gel 9.7 g10. gel wettingagent2 mineraloil 1g 2 ml- slap spatula stirring rod levigate () 11. 10 5 .Disnto .loratadine .Dimenhydrate .Cream steroid 12. TB rifampicinB.Rifampin - rifampin (--) ( ) - rifampin ( ) 1 2 ( ) - ( ) rifampin rifampin - rifampin rifampin Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 164 rifampin rifampin rifampin 13. 14. cimetidine 200 mg/tsp. 1 fl.oz. cimetidine 400 mg - 3 1 fl.oz. = 30 ml 5 ml 15. cimetidine cimetidine suspension- levigating agent syrup15 ml 16. cylinder 17. 5 paracetamol - 18. 19. . sugar coat tablet . cream . vaginal tablet . elixir () . plastills () 20. Emulax 30 21. drug infor , MIMs, USP NF - drug infor 22. DI co trimoxazole Drug infor matindale - drug info drug infor Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 16523. amoxyclinesuspension Chlophenilamine syrup . 16 . . . 074 212586 10 51 ..... Chlophenilamine syrup 60ml (2mg/5ml) 2///3-4 6-8.. ...... alcohol . 16 . . . 074 212586 10 51 ..... amoxyclinesuspension 60 ml(125 mg/5ml) 2///3 8.. penicillin 24. Pseudoepridine () Pseudoepridine+ tripolidine () -Pseudoepridine 2 Actifed 25. 21 (mervelon)- 1 21 1 ( 1) 5 ( ) 7 2-4 7 2.1 1 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 166 2 14 2 2 7 2 14 7 3 7 2.2. 1 2.3. tetracyclines,penicillins,quinolones, cephalosporins metronidazole progestin 2.4. rifampicin enzymeinducer 4 rifampicin enzyme inducer 3. - 2-3 - - - - 2-3 26.dose dose mg/kg/day q . hr. 10 kg 27. G6PD penicillin -Co trimazole sulfa penicillin-Amitriptalline 28. 2 -Aspirin 81 mg/Simvastatin BY 473103 RSU Rx 18 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 167 OSPE PracticeForExam Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 168 1. capsule amoxicillin 500 mg 50 ( amoxicillin 250 , 500 mg) 2. ......................... pregnancy risk factor ( MIMs, drug information, drug use in pregnancy ) 3. (accuhaler) 4. Roaccutane 17 2 1 ? ............. Roaccutane 5. Methronidazole 32 mg/ml suspension 25 mlMethronidazole 400 mg Methronidazole : Diazepam 5 mg 2 Glycerin qs Vehicle ad qs25 ml 6. : Diazepam 5 mg 2 glycerin paste 7. vehicle rinse 8. 9. DRP Rx Lasix40 mg hs Aspirin60 mg QAM glibenclamide 5 mg 1*1 pc OSPE Practice I Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 16910. S=special control drug E-D = external use dangerous drug P4=psychotropic substance schedule 4 D =dangerous drug NDD =nondangerous drug N3= narcotic drug schedule 3 E=external use nondangerous drug Phenylbutazone Prednisolone cream Lorazepam Acyclovir Alum milk 11. : ( urticaria ) : 22 2 ..... urticaria 12. : : Dexoph 26 13. alcohol 20 %50 mlalcohol 80 % 100 ,50, 25, 10 ml100500 50mlvolumetric flaskpipetstirring rod N1V1 = N2V220*50 = 80*V2 v2 = 12.5 ml 14. 51 Total cholesterol 267 mg/dlTG 135 mg/dl LDL167 mg/dl HDL67mg/dl simvastatin 10 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 17015. Drug interaction consult RxErythromycin CPM Theophyline Salbutamol Erythromycin Theophyline Erythromycin Enz. Inhibitor Theophyline Theophyline 16. 40 Haldol Midazolam 1 Haldol Midazolam P2 17. dosage form filmTurbuhaler Effervescent SuppositoryLozenges 18. vanishing cream Chloramphenicol0.5 g vanishing cream qs 5 g vanishing cream 4.5 g 19. cream base 20. warfarin S/E 21. Theophyline SR 22. 18 4 .. 25 .. 23. Amphotericin B NSS 24. Paracetamol syrup 120 mg/mlcounter pain plus Paracetamol tab100 tabdimenhydrinate 50 tab Amoxicillin dry syrup T.A. cream 0.1 % 120 mlMebendazole 100 mg 6 tab 5 Aspirin grain 5 10 tab 25. 3 20 kg amoxicillin dry syrup Coamox 125 mg/5ml 60ml , Coamox 250mg/5ml60ml Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 171 1. conselling 28 ... 2. 5 1.codeine (ropec) 2.ORS 3. 4. 5. 3. 3 antibiotic dry syrup paracetamol choramphenicol 12 ........... ( Exp. 16/07/08 .. .. ???) 4. form erythomycin dry syrup remington version 5. 5 antibiotic 6. digoxin therapuetic 7. CPM 20 8. tegaserod preg cat MIMS 9. 2 2 glipizide cholestyramine (queastran) (..) 10. phentermine 2 OSPE Practice II Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 17211. cafergot fluoxitine 12. LDL TG, TC HDL 40 TC = LDL+HDL+(TG/5) LDL 13. 5 25 . common cold ... 5 .. 14. consult 2 ofloxacin alum milk 2 2 alum milk sucralfate sucralfate 1 . oflox 2 . 15. isotretinoin (Retin-A) .. 16. 3 3 ... 17. calcium calcium tablets calcium effervescent calcium 18. talcum 4 g calamine 1 g talc. qs to 5 g triple check tech. tapping 19. calamine dusting powder talcum glycerine .. geometric dilution slap&spatula reflex . . SE propanolol .. 20. dosage form 1. cotrimazole vagianl supp. 2 step film coat tablet2. alc. ( propanolol ) ... Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 1733. soft (gelatin) capsules4. gel bubble ...5. calamine lotion suspension 21. 3 metronidazole 400 . 32*25 = 800 2 22. metro 2 propanolol .... glycerine .. triple check metro ... 23. suspension purified water 10 ml vehicle 15 ml 2 front 100 ... ... 24. paracetamol 6 .........mg/kg/dose para syr 120 mg/5ml para drop 25.( ) Lomotil,Ropec,CPZ,Amitriptyline Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 174 1 generic name, local made Glyburide 1. generic/ synonyms............................................................................ (local made) ............................................................................ ........................................................................................ 2. synonym 5 2 Ketoconazole 3 mg/kg/day candidiasis .......().................................................................................................... 3 Erythromycin 1g ErythromycinEstolate .......().......................................................... ............................................... ................................ 5 pregnancy category 25 3 penicillin erythromycin pregnancy category................................................................................................. ........................................................................................ Pregnancy OSPE Practice III Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 175 6 Stability/ Compatibility Phenytoin .......................... ................................................................... ........................................................................... 7 pregnancy category 1. Acebutolol pregnancy category B; D in 2nd & 3 rd trimester 2. Alfentanil pregnancy category C; D if used for prolonged periods or in high doses at term 3. Aspartam pregnancy category B; C in woman w/phenylketonuria 4. Cotrimoxazole pregnancy category C; D if used near term 5. Folic acid pregnancy category A; C if dose > 0.8 mg/day pregnancy category Acebutolol Alfentanil Aspartam Cotrimoxazole Folic acid 8 : - 8 50 . - phenobarbital 1 7 2-3 - 1. ................................................. 2. ................................................. 3.................................................. 4. ............................................................................... Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 1769 - 1 : MIMS 1. Prednisolone tablet 2. Triamcinolone acetonide oral paste 3. 60 . 4. Isosorbide dinitrate sublingual 5. fentanyl 6. 7. Diazepam tablet 8. Phenobarbital capsule 9. Insulin 10. 11. Lomotil (diphenoxylate+atropine) 12. Triazolam tablet 13. Cytotec (prostaglandin E1) 10 - 1 : MIMS / 1. Flunitrazepam tablet 2. Metformin HCl tablet 3. Selegiline HCl 4. codeine 125 . 5. Roaccutane Isotretinoin capsule 6. Viagra sildenafil Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 17711 22 2(9..47) pharyngitis paracetamol(Tylenol)500mg24-6amoxicillin (Ibiamox) 500 mg 1 3 -- (11.. 47) maculopapular rashamoxicillinmaculopapularrash Amoxicillin roxithomycin chlorpheniramine amoxicillinmaculopapularrash (possible) amoxicillin Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 178 1. .. 2 Rx Paracetamol suspension # 50 ml (20 mg/ml) 1 tsp q 6h prn : **** **** : 1. Paracetamol tablets 500 mg 2 5 2... 2 Paracetamol suspension (20 mg/ml) 1 6 ( ) 2 2 1 2. Paracetamol suspension 50 ml Rx Paracetamol 20 mg/ml Syrup to 50 ml : 1. Paracetamol tablets 500 mg 2 ( 0 ) 2 2.- Cylinder 50 ml ( 1 ) - syrup 3/4( ~ 37.5 ml ) ( 0.5 ) - syrup 3/4 ( 0.5 ) 2 3. 2 4. tare stirring rod 2 5. tare 2 ** : Beaker syrup stirring rod (0 ) OSPE Practice Final Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 1793. Gallic acid 3.2 IUPAC : 1. Merck Index 3 2. - 2 - 3 ,4,5-trihydroxybenzoic acid 2 - Reference (,volume,year,page ) Merck Index 11th edition (1989) p.680 3 4. Vitamin B complex 100 : - 1 - Tripple check (, ) ** 0 2 - 5 2 - ()2 - 1 - Spatula1 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 180 5. : - ( 2 ) 2 - levonorgestrel 0.75 mg 2 - 72 . 12 . 2 2 - - - - 4 - - 4 6. 60 Rx Warfarin 3 mg 1 x 1 p.o. ()# 30

: 1. Warfarin 3 mg 30 1 2. : 1 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 1813. 1 1 1 4. 2 5. 2 6. Warfarin2 7. 1 7. 1% iodine solution 30 ml strong iodine solution iodine 1% 10% strong iodine solution : - 10% strong iodine solution 3 ml10 8. 1% iodine solution 30 ml 10% strong iodine solution : 1. 10% strong iodine solution2 2. - 10 ml 3 ml (2 ) 25 50 0 - 50 ml 30 ml (2 ) 10 25 0 2 2 3. 2 4. 2 5. 2 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 182 9. Griseofulvin 1 x 1 pc # 90 : 1. : 1 2. 1 1 1 3. 2 4. 2 5. 2 6. 2 10. DUOFILM : - : 2 - 1. 5 2 2. 2 3. 2 4. 2 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 183 11. Roaccutane capsule 5% benzoyl peroxide : /................. / - Rocautane capsule 4 - ( teratogennic) 1 2 - 5 %benzoyl peroxide 2 - 15-30 2 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 184 12. 10% sulfur ointment Sulfur0.5gm Creambase q.s. 5gm . Cream base : - spatula& slab Key : Slab and spatula , spatula rubber ( sulfur rubber stainless ) slab spatula 2 - levigating agent Key : levigating agent ( cold cream, ointment ,W/Ocream mineral oil, vanishing cream,PEG ointment O/W emulsion glycerin) leviagate smooth paste - geometric dilution Key : Slab levigate spatula 2 - Key : 2 - 2 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 18513. 1% Glycerin Glycerin0.5ml Waterq.s.50ml : - Calibrate dropper Cylinder 10 ml dropper cylinder 25, 50 0 2 - dropper 2 - lower meniscus2 - calibrate dropper 2ml 0.5ml. 2 - 2 14. 1. Dexamethasone tablet 2. Diazepam 3. 60 ml 4. Lomotil 5. Codepect : Item Dexamethasone tablet Diazepam 60 ml Lomotil 3 Codepect 3 10 : 1 / 0.5 0.5 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 18615. Glyburide : Drug information handbook synonyms = Glybenclamide TIMS local made Benclamin Cytagon Debtan Diabeedol Diabenol Diclanil Diabelet Gliben Glibesyn Glybetic Glybic Gluconil Gluzo 16. (migraine) 2 Cafergot #20 Flunarizine 5 mg #30 ..................................................................... .............................................................. ................................................................... ............................................................. ........... ........... ................... ................... ...................................... 30 ................... ................... ................... Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 18717. 10% sulfur ointment Sulfur0.5 gm Cold creamq.s. 5 gm Cream base : - 2 - Cold cream 0 , 2 2 - Spatula Stirring rod 2 2 Spatula Stirring rod 0 2 - 4.5 gm 5 gm 0 2 - Spatula 1 1 0 2 18. Peppermint Water (10 ) : : - Plaited filter ( Plain filter 0 ) 2 - filter funnel stand( stand funnel flask cylinder 0 ) 2 - flask filtrate( Beaker 0 ) 1 - rinse ( rinse 0 ) 2 - funnel stirrer ( stirrer 0 ) 1 - funnel oil( 0 ) 2 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 18819. 1.ENO 2.Vitamin B-complex 3.4.Protosedyl 5.Sara strawberry 6. 7.Adalat CR8.ORS : 1.ENO(Effervescent granules) 2.Vitamin B-complex(Sugar coated tablets) 3. (Soft gelatin capsules) 4.Protosedyl (Suppositories) 5.Sara strawberry (Suspensions) 6. (Mixtures) 7.Adalat CR(Controlled release tablets) 8.ORS (Powders) : 1.25 10 20. Rx Salbutamol MDI 1 puff prn # 1 MD. : - 1 - 1 - 1 - 3-4 1-2 2 - 1 () 2 - (4-10 ) 2 - 1 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 18921. RxNifedipin SR x 2 pc #30 ASA gr I1 tab q 6 h, prn#90 : Nifedipin SR - Nifedipin SR 3 - ( 1 1 )2 ASA gr I - Aspirin( ) 2 -ASA gr I 2 1 3 22. 40 Rheumatoid arthritis (RA) Rx Methotrexate tablet 2.5 mg3 tab/week ( on Mon. )#12 : - Methotrexate 2.5 12 1 - ... Rheumatoid1 - 3 1 - 2 - 2 - 2 - 1 Comprehensive Pharmacy Review OSPE Pharmacy Student Rx24Khon Kaen University 190 (Pharmaceutics) 1) 2) Slab & Spatula Levigating