0.1

Desulfovibrio vulgaris str. Hildenborough YP_011484

Pelotomaculum thermopropionicum SI YP_001212971Alkaliphilus metalliredigens QYMF YP_001318393

Clostridium phytofermentans ISDg YP_001558292Clostridium ljungdahlii DSM 13528 YP_003779354

Clostridium novyi NT YP_878968Clostridium tetani E88 NP_781592

Clostridium novyi NT YP_878876Clostridium novyi NT YP_877304

Clostridium beijerinckii NCIMB 8052 YP_001311126Oscillibacter valericigenes Sjm18-20 YP_004881457

Shewanella putrefaciens CN-32 YP_001181742Vibrio sp. EJY3 YP_005023151

Pectobacterium wasabiae WPP163 YP_003261426Rhodobacter capsulatus SB 1003 YP_003578336

Rhodospirillum rubrum ATCC 11170 YP_426004Rhodopseudomonas palustris BisB18 YP_531058

Clostridium botulinum B str. Eklund 17B YP_001885706Leptotrichia buccalis C-1013-b YP_003164803

Sebaldella termitidis ATCC 33386 YP_003307872Enterobacteriaceae bacterium strain FGI 57 YP_007341684Sebaldella termitidis ATCC 33386 YP_003308725Vibrio sp. EJY3 YP_005023261

Tolumonas auensis DSM 9187 YP_00289309012 Enterobacteria species (BV = 100%)

Spirochaeta smaragdinae DSM 11293 YP_003805842Parabacteroides distasonis ATCC 8503 YP_001303223

Eubacterium limosum KIST612 YP_003960437Edwardsiella tarda FL6-60 YP_005698020

9 Enterobacteria species (BV = 34%)9 Enterobacteria species (BV = 67%)

Pelobacter carbinolicus DSM 2380 YP_006716660Proteus mirabilis HI4320 YP_002152416

Serratia marcescens FGI94 YP_007343021Vibrio furnissii NCTC 11218 YP_004991565

7 Enterobacteria species (BV = 43%)Desulfitobacterium hafniense Y51 YP_521238Desulfotomaculum ruminis DSM 2154 YP_004545625

Desulfotomaculum reducens MI-1 YP_001114602Desulfosporosinus orientis DSM 765 YP_004973311Desulfosporosinus meridiei DSM 13257 YP_006624071

Alkaliphilus metalliredigens QYMF YP_001321611Alkaliphilus oremlandii OhILAs YP_001513925

Clostridium ljungdahlii DSM 13528 YP_003782108Clostridium phytofermentans ISDg YP_001558532Clostridium saccharolyticum WM1 YP_003824151

Olsenella uli DSM 7084 YP_003800311Streptococcus intermedius JTH08 YP_006469537Streptococcus dysgalactiae subsp. equisimilis RE378 YP_006860441

Clostridium botulinum F str. Langeland YP_001391411Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 YP_002479938

Desulfotalea psychrophila LSv54 YP_065560Desulfovibrio alaskensis G20 YP_389770

Desulfovibrio hydrothermalis AM13 = DSM 14728 YP_007325733Desulfovibrio salexigens DSM 2638 YP_002990075

Desulfovibrio alaskensis G20 YP_389543Desulfotomaculum kuznetsovii DSM 6115 YP_004517845Desulfitobacterium dehalogenans ATCC 51507 YP_006428597

Desulfotomaculum ruminis DSM 2154 YP_004544048Desulfotomaculum reducens MI-1 YP_001114081

Desulfitobacterium dehalogenans ATCC 51507 YP_006428627Desulfitobacterium hafniense DCB-2 YP_002456870Desulfitobacterium hafniense Y51 YP_516650

Desulfovibrio desulfuricans ND132 YP_005168027Desulfomicrobium baculatum DSM 4028 YP_003158644

Desulfotalea psychrophila LSv54 YP_066762Pectobacterium wasabiae WPP163 YP_003260804

Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 YP_002480015Desulfomicrobium baculatum DSM 4028 YP_003158095

Desulfovibrio vulgaris str. Hildenborough YP_012037Desulfovibrio alaskensis G20 YP_387768Rhodomicrobium vannielii ATCC 17100 YP_004013872

Alkaliphilus oremlandii OhILAs YP_001514214Desulfotomaculum ruminis DSM 2154 YP_004545679

Clostridium difficile R20291 YP_003217451Clostridium kluyveri DSM 555 YP_001396380

Alkaliphilus metalliredigens QYMF YP_001319809Pelobacter carbinolicus DSM 2380 YP_006717121

Desulfovibrio magneticus RS-1 YP_002952805Desulfovibrio hydrothermalis AM13 = DSM 14728 YP_007325494

Desulfovibrio salexigens DSM 2638 YP_002991691Clostridium sp. SY8519 YP_004708500

Desulfomonile tiedjei DSM 6799 YP_006447102Olsenella uli DSM 7084 YP_003800138

Clostridium botulinum BKT015925 YP_004396285Tannerella forsythia ATCC 43037 YP_005013103

Syntrophobotulus glycolicus DSM 8271 YP_004266818Olsenella uli DSM 7084 YP_003801019

Clostridium difficile R20291 YP_003216664Lactobacillus plantarum WCFS1 YP_004890257

Sphaerochaeta coccoides DSM 17374 YP_004410739Olsenella uli DSM 7084 YP_003801189

Coriobacterium glomerans PW2 YP_004372167Sebaldella termitidis ATCC 33386 YP_003309802Melissococcus plutonius ATCC 35311 YP_004455507

Clostridium beijerinckii NCIMB 8052 YP_00130784113 Streptococcus species (BV = 97%)

Acidaminococcus intestini RyC-MR95 YP_004897370Desulfosporosinus acidiphilus SJ4 YP_006465539

Spirochaeta smaragdinae DSM 11293 YP_003801977Desulfatibacillum alkenivorans AK-01 YP_002431741

Desulfatibacillum alkenivorans AK-01 YP_002429341Sphaerochaeta coccoides DSM 17374 YP_004410728

Clostridium ljungdahlii DSM 13528 YP_003780757Clostridium beijerinckii NCIMB 8052 YP_001307460

Gallionella capsiferriformans ES-2 YP_003847422Desulfococcus oleovorans Hxd3 YP_001530073

Desulfatibacillum alkenivorans AK-01 YP_002430002Desulfobacula toluolica Tol2 YP_006762114

Desulfomonile tiedjei DSM 6799 YP_006447324Bacteroides fragilis NCTC 9343 YP_213745

Desulfobacterium autotrophicum HRM2 YP_002601708Halanaerobium hydrogeniformans YP_003994530

Ilyobacter polytropus DSM 2926 YP_003966197Ilyobacter polytropus DSM 2926 YP_003966190

Mahella australiensis 50-1 BON YP_004463354Enterobacter cloacae SCF1 YP_003943560

Treponema azotonutricium ZAS-9 YP_004528865Syntrophobotulus glycolicus DSM 8271 YP_004266816

Sebaldella termitidis ATCC 33386 YP_003310030Enterobacter cloacae SCF1 YP_003943814

Sebaldella termitidis ATCC 33386 YP_003310469Bacteroides thetaiotaomicron VPI-5482 NP_811868

Coriobacterium glomerans PW2 YP_004372426Prevotella ruminicola 23 YP_003574839

Methanothermobacter thermautotrophicus str. Delta H NP_275488Treponema brennaborense DSM 12168 YP_004438862

Methanobacterium formicicum DSM 3637 ZP_11178885

Desulfovibrio desulfuricans ND132 YP_005167594Desulfovibrio salexigens DSM 2638 YP_002993114

Acetobacterium woodii DSM 1030 YP_005269165Desulfitobacterium hafniense Y51 YP_519242Acetobacterium woodii DSM 1030 YP_005269162

Desulfobacula toluolica Tol2 YP_006759016Aromatoleum aromaticum EbN1 YP_158058

Geobacter daltonii FRC-32 YP_002537904Geobacter metallireducens GS-15 YP_006720509Geobacter daltonii FRC-32 YP_002537894

Desulfobacula toluolica Tol2 YP_006759356Desulfatibacillum alkenivorans AK-01 YP_002431362

Desulfobacula toluolica Tol2 YP_006759355Slackia heliotrinireducens DSM 20476 YP_003144113

Desulfatibacillum alkenivorans AK-01 YP_002431363Desulfatibacillum alkenivorans AK-01 YP_002430893

Archaeoglobus fulgidus DSM 4304 NP_070279Archaeoglobus sp. PM70-1 AGK61142

Natranaerobius thermophilus JW NM-WN-LF YP_001918628Clostridium difficile R20291 YP_003219619

Desulfotomaculum ruminis DSM 2154 YP_004544080Clostridium kluyveri DSM 555 YP_001393724

Oscillibacter valericigenes Sjm18-20 YP_004883803Desulfotomaculum reducens MI-1 YP_001114294

Desulfosporosinus acidiphilus SJ4 YP_006465540Desulfosporosinus orientis DSM 765 YP_004971939

Desulfosporosinus meridiei DSM 13257 YP_006622841Alkaliphilus metalliredigens QYMF YP_001318469

Clostridium botulinum F str. Langeland YP_001392535Geobacter sulfurreducens PCA NP_953151

Geobacter bemidjiensis Bem YP_002139304Geobacter sp. M18 YP_004199094Thermanaerovibrio acidaminovorans DSM 6589 YP_003317950

Thermovirga lienii DSM 17291 YP_004933394Odoribacter splanchnicus DSM 20712 YP_004254772

Hippea maritima DSM 10411 YP_004339399Deferribacter desulfuricans SSM1 YP_003497308

Denitrovibrio acetiphilus DSM 12809 YP_003504240Coprothermobacter proteolyticus DSM 5265 YP_002247823

Candidatus Korarchaeum cryptofilum OPF8 YP_001736954Desulfobacterium autotrophicum HRM2 YP_002606146

Desulfomicrobium baculatum DSM 4028 YP_003158861Parabacteroides distasonis ATCC 8503 YP_001302179

Bacteroides vulgatus ATCC 8482 YP_001298730Anaerobaculum mobile DSM 13181 YP_006444861

Thermotoga lettingae TMO YP_001470771Tepidanaerobacter acetatoxydans Re1 YP_007270701Tepidanaerobacter acetatoxydans Re1 YP_004459566

Thermococcus kodakarensis KOD1 YP_182703Aciduliprofundum boonei T469 YP_003482542

Aciduliprofundum sp. MAR08-339 YP_007246921Thermococcus sibiricus MM 739 YP_002994043

Thermococcus litoralis DSM 5473 ZP_09729921

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