1. yamada, h., shinmura, k., ito, h., kasami, m., sasaki...
TRANSCRIPT
1. Yamada, H., Shinmura, K., Ito, H., Kasami, M., Sasaki, N., Shima,
H., Ikeda, M., Tao, H., Goto, M., Ozawa, T., Tsuneyoshi, T., Tanioka, F.,
and Sugimura, H., Germline alterations of the CDH1 gene in familial gastric
cancer in the Japanese population. Cancer Sci, 2011. 102(10): 1782-88.
2. Tamaki, Y., Honda, M., Muroi, Y., Arai, T., Sugimura, H., Matsubara,
Y., Kanno, S., Ishikawa, M., Hirasawa, N., and Hiratsuka, M., Novel Single
Nucleotide Polymorphism of the CYP2A13 gene in Japanese individuals. Drug
Metab Pharmacokinet, 2011. 26(5): 544-547.
3. Tamaki, Y., Arai, T., Sugimura, H., Sasaki, T., Honda, M., Muroi,
Y., Matsubara, Y., Kanno, S., Ishikawa, M., Hirasawa, N., and Hiratsuka,
M., Association between Cancer Risk and Drug Metabolizing Enzyme Gene
(CYP2A6, CYP2A13, CYP4B1, SULT1A1, GSTM1, and GSTT1) Polymorphisms in
Japanese Cases of Lung Cancer. Drug Metab Pharmacokinet, 2011. 26(5):
516-522.
4. Sugimura, H., Tao, H., Suzuki, M., Mori, H., Tsuboi, M., Matsuura,
S., Goto, M., Shinmura, K., Ozawa, T., Tanioka, F., Sato, N., Matsushima,
Y., Kageyama, S., Funai, K., Chou, P.H., and Matsuda, T., Genetic
susceptibility to lung cancer. Front Biosci (Schol Ed), 2011. 3: 1463-77.
5. Shinmura, K., Igarashi, H., Goto, M., Tao, H., Yamada, H., Matsuura,
S., Tajima, M., Matsuda, T., Yamane, A., Funai, K., Tanahashi, M., Niwa,
H., Ogawa, H., and Sugimura, H., Aberrant Expression and Mutation-Inducing
Activity of AID in Human Lung Cancer. Ann Surg Oncol, 2011. 18(7): 2084-92
6. Shinmura, K., Goto, M., Suzuki, M., Tao, H., Yamada, H., Igarashi,
H., Matsuura, S., Maeda, M., Konno, H., Matsuda, T., and Sugimura, H.,
Reduced expression of MUTYH with suppressive activity against mutations
caused by 8-hydroxyguanine is a novel predictor of a poor prognosis in human
gastric cancer. J Pathol, 2011. 225(3): 414-23.
7. Setoguchi, T., Kikuchi, H., Yamamoto, M., Baba, M., Ohta, M., Kamiya,
K., Tanaka, T., Baba, S., Goto-Inoue, N., Setou, M., Sasaki, T., Mori, H.,
Sugimura, H., and Konno, H., Microarray analysis identifies versican and
CD9 as potent prognostic markers in gastric gastrointestinal stromal tumors.
Cancer Sci, 2011. 102(4): 883-9.
8. Saeki, N., Saito, A., Choi, I.J., Matsuo, K., Ohnami, S., Totsuka,
H., Chiku, S., Kuchiba, A., Lee, Y.S., Yoon, K.A., Kook, M.C., Park, S.R.,
Kim, Y.W., Tanaka, H., Tajima, K., Hirose, H., Tanioka, F., Matsuno, Y.,
Sugimura, H., Kato, S., Nakamura, T., Nishina, T., Yasui, W., Aoyagi, K.,
Sasaki, H., Yanagihara, K., Katai, H., Shimoda, T., Yoshida, T., Nakamura,
Y., Hirohashi, S., and Sakamoto, H., A functional SNP in MUC1, at chromosome
1q22, determines susceptibility to diffuse-type gastric cancer Short
title: MUC1is a gastric cancer susceptibility gene. Gastroenterology, 2011.
140(3): 892-902.
9. Kawahara, N., Sugimura, H., Nakagawara, A., Masui, T., Miyake, J.,
Akiyama, M., Wahid, I.A., Hao, X., and Akaza, H., The 6th Asia Cancer Forum:
What Should We Do to Place Cancer on the Global Health Agenda? Sharing
Information Leads to Human Security. Jpn J Clin Oncol, 2011.
10. Kawahara, N., Roh, J.K., Akaza, H., Inoue, H., Shibuya, K., Iwasaki,
M., Tsuji, T., Nishiyama, M., Nakagawara, A., Watanabe, K., Nozaki, S.,
Inoue, M., Sugimura, H., Miyake, J., and Li, F., The 7th Asia Cancer Forum:
From the Perspective of Human Security, How Can We Collaborate as Asians
in Order to Place Cancer on the Global Health Agenda? How Can We Fill in
the Gaps that Exist Among Us? Jpn J Clin Oncol, 2011.
11. Kahyo, T., Iwaizumi, M., Shinmura, K., Matsuura, S., Nakamura, T.,
Watanabe, Y., Yamada, H., and Sugimura, H., A novel tumor-derived SGOL1
variant causes abnormal mitosis and unstable chromatid cohesion. Oncogene,
2011. 30(44): 4453-63.
12. Ikematsu, Y., Tamura, H., Nakata, Y., Hayashi, T., Kanai, T.,
Hirayama, K., Mori, H., Ozawa, T., Hasegawa, S., Okawada, T., Kageyama,
S., Sugimura, H., and Nishiwaki, Y., Metachronous multiple adenocarcinomas
of the pancreas. Int J Clin Oncol, 2011.
13. Funai, K., Sugimura, H., Morita, T., Shundo, Y., Shimizu, K., and
Shiiya, N., Lymphatic Vessel Invasion is a Significant Prognostic Indicator
in Stage IA Lung Adenocarcinoma. Ann Surg Oncol, 2011.
14. Wang, J., Dong, Y., Wang, X., Ma, H., Sheng, Z., Li, G., Lu, G.,
Sugimura, H., and Zhou, X., Expression of EphA1 in gastric carcinomas is
associated with metastasis and survival. Oncol Rep, 2010. 24(6): 1577-84.
15. Tsuboi, M., Mori, H., Bunai, T., Kageyama, S., Suzuki, M., Okudela,
K., Takamochi, K., Ogawa, H., Niwa, H., Shinmura, K., and Sugimura, H.,
Secreted form of EphA7 in lung cancer. Int J Oncol, 2010. 36(3): 635-40.
16. Toyoshima, M., Chida, K., Kono, M., Kaida, Y., Nakamura, Y., Suda,
T., and Sugimura, H., IgG4-related lung disease in a worker occupationally
exposed to asbestos. Intern Med, 2010. 49(12): 1175-8.
17. Tao, H., Shinmura, K., Yamada, H., Maekawa, M., Osawa, S.,
Takayanagi, Y., Okamoto, K., Terai, T., Mori, H., Nakamura, T., and Sugimura,
H., Identification of 5 novel germline APC mutations and characterization
of clinical phenotypes in Japanese patients with classical and attenuated
familial adenomatous polyposis. BMC Res Notes, 2010. 3(1): 305.
18. Sugimura, H., Wang, J.D., Mori, H., Tsuboi, M., Nagura, K., Igarashi,
H., Tao, H., Nakamura, R., Natsume, H., Kahyo, T., Shinmura, K., Konno,
H., Hamaya, Y., Kanaoka, S., Kataoka, H., and Zhou, X.J., EPH-EPHRIN in
human gastrointestinal cancers. World J Gastrointest Oncol, 2010. 2(12):
421-8.
19. Sugimura, H., Mori, H., Nagura, K., Kiyose, S., Hong, T., Isozaki,
M., Igarashi, H., Shinmura, K., Hasegawa, A., Kitayama, Y., and Tanioka,
F., Fluorescence in situ hybridization analysis with a tissue microarray:
'FISH and chips' analysis of pathology archives. Pathol Int, 2010. 60(8):
543-50.
20. Sugimoto, M., Nishino, M., Kodaira, C., Yamade, M., Ikuma, M.,
Tanaka, T., Sugimura, H., Hishida, A., and Furuta, T., Esophageal mucosal
injury with low-dose aspirin and its prevention by rabeprazole. J Clin
Pharmacol, 2010. 50(3): 320-30.
21. Shinmura, K., Tao, H., Nagura, K., Goto, M., Matsuura, S., Mochizuki,
T., Suzuki, K., Tanahashi, M., Niwa, H., Ogawa, H., and Sugimura, H.,
Suppression of hydroxyurea-induced centrosome amplification by NORE1A and
down-regulation of NORE1A mRNA expression in non-small cell lung carcinoma.
Lung Cancer, 2010.
22. Shinmura, K., Kageyama, S., Igarashi, H., Kamo, T., Mochizuki, T.,
Suzuki, K., Takahashi, M., Niwa, H., Ogawa, H., and Sugimura, H., EML4-ALK
fusion transcripts in immunohistochemically ALK-positive non-small cell
lung canrcinomas. Experimental and therapeutic medicine, 2010. 1:
271-275.
23. Sato, N., Kageyama, S., Chen, R., Suzuki, M., Tanioka, F., Kamo,
T., Shinmura, K., Nozawa, A., and Sugimura, H., Association between
neurexin 1 (NRXN1) polymorphisms and the smoking behavior of elderly
Japanese. Psychiatr Genet, 2010. 20(3): 135-6.
24. Sato, N., Kageyama, S., Chen, R., Suzuki, M., Mori, H., Tanioka,
F., Yamada, H., Kamo, T., Tao, H., Shinmura, K., Nozawa, A., and Sugimura,
H., Association between neuropeptide Y receptor 2 polymorphism and the
smoking behavior of elderly Japanese. J Hum Genet, 2010. 55(11): 755-60.
25. Nishino, M., Sugimoto, M., Kodaira, C., Yamade, M., Uotani, T.,
Shirai, N., Ikuma, M., Tanaka, T., Sugimura, H., Hishida, A., and Furuta,
T., Preventive Effects of Lansoprazole and Famotidine on Gastric Mucosal
Injury Induced by Low-Dose Aspirin in Helicobacter pylori-Negative Healthy
Volunteers. J Clin Pharmacol, 2010.
26. Morita, Y., Ikegami, K., Goto-Inoue, N., Hayasaka, T., Zaima, N.,
Tanaka, H., Uehara, T., Setoguchi, T., Sakaguchi, T., Igarashi, H.,
Sugimura, H., Setou, M., and Konno, H., Imaging mass spectrometry of gastric
carcinoma in formalin-fixed paraffin-embedded tissue microarray. Cancer
Sci, 2010. 101(1): 267--273.
27. Kawahara, N., Sugimura, H., Nakagawara, A., Masui, T., Miyake, J.,
Akiyama, M., Wahid, I.A., Hao, X., and Akaza, H., The 6th Asia cancer forum:
what should we do to place cancer on the global health agenda? Sharing
information leads to human security. Jpn J Clin Oncol, 2010. 41(5): 723-9.
28. Goto, M., Shinmura, K., Tao, H., Tsugane, S., and Sugimura, H.,
Three novel NEIL1 promoter polymorphisms in gastric cancer patients. World
Journal of Gastrointestinal Oncology, 2010. 2(2): 117-120.
29. Goto, M., Shinmura, K., Nakabeppu, Y., Tao, H., Yamada, H.,
Tsuneyoshi, T., and Sugimura, H., Adenine DNA glycosylase activity of 14
Human MutY homolog (MUTYH) variant proteins found in patients with
colorectal polyposis and cancer. Hum Mutat, 2010. 31: E1881-74.
30. Chou, P.H., Kageyama, S., Matsuda, S., Kanemoto, K., Sasada, Y.,
Oka, M., Shinmura, K., Mori, H., Kawai, K., Kasai, H., Sugimura, H., and
Matsuda, T., Detection of lipid peroxidation-induced DNA adducts caused
by 4-oxo-2(E)-nonenal and 4-oxo-2(E)-hexenal in human autopsy tissues.
Chem Res Toxicol, 2010. 23(9): 1442-8.
31. Akieda-Asai, S., Zaima, N., Ikegami, K., Kahyo, T., Yao, I.,
Hatanaka, T., Iemura, S., Sugiyama, R., Yokozeki, T., Eishi, Y., Koike,
M., Ikeda, K., Chiba, T., Yamaza, H., Shimokawa, I., Song, S.Y., Matsuno,
A., Mizutani, A., Sawabe, M., Chao, M.V., Tanaka, M., Kanaho, Y., Natsume,
T., Sugimura, H., Date, Y., McBurney, M.W., Guarente, L., and Setou, M.,
SIRT1 Regulates Thyroid-Stimulating Hormone Release by Enhancing
PIP5Kgamma Activity through Deacetylation of Specific Lysine Residues in
Mammals. PLoS One, 2010. 5(7): e11755.
32. Yamada, H., Shinmura, K., Yamamura, Y., Kurachi, K., Nakamura, T.,
Tsuneyoshi, T., Yokota, N., Maekawa, M., and Sugimura, H., Identification
and characterization of a novel germline p53 mutation in a patient with
glioblastoma and colon cancer. Int J Cancer, 2009. 125(4): 973-6.
33. Yamada, H., Shinmura, K., Goto, M., Iwaizumi, M., Konno, H., Kataoka,
H., Yamada, M., Ozawa, T., Tsuneyoshi, T., Tanioka, F., and Sugimura, H.,
Absence of germline mono-allelic promoter hypermethylation of the CDH1 gene
in gastric cancer patients. Mol Cancer, 2009. 8(1): 63.
34. Takai, T., Kanaoka, S., Yoshida, K., Hamaya, Y., Ikuma, M., Miura,
N., Sugimura, H., Kajimura, M., and Hishida, A., Fecal cyclooxygenase 2
plus matrix metalloproteinase 7 mRNA assays as a marker for colorectal
cancer screening. Cancer Epidemiol Biomarkers Prev, 2009. 18(6): 1888-93.
35. Suzuki, M., Nagura, K., Igarashi, H., Tao, H., Midorikawa, Y.,
Kitayama, Y., and Sugimura, H., Copy number estimation algorithms and
fluorescence in situ hybridization to describe copy number alterations in
human tumors. Pathol Int, 2009. 59(4): 218-28.
36. Seike, M., Goto, A., Okano, T., Bowman, E.D., Schetter, A.J.,
Horikawa, I., Mathe, E.A., Jen, J., Yang, P., Sugimura, H., Gemma, A., Kudoh,
S., Croce, C.M., and Harris, C.C., MiR-21 is an EGFR-regulated
anti-apoptotic factor in lung cancer in never-smokers. Proc Natl Acad Sci
U S A, 2009. 106(29): 12085-90.
37. Okudela, K., Yazawa, T., Woo, T., Sakaeda, M., Ishii, J., Mitsui,
H., Shimoyamada, H., Sato, H., Tajiri, M., Ogawa, N., Masuda, M., Takahashi,
T., Sugimura, H., and Kitamura, H., Down-Regulation of DUSP6 Expression
in Lung Cancer --Its Mechanism and Potential Role in Carcinogenesis. Am
J Pathol, 2009. 175(2): 867-881.
38. Okudela, K., Yazawa, T., Suzuki, T., Sugimura, H., and Kitamura,
H., Role of 3'-phosphoinositides in oncogenic KRAS-induced modulation of
shape and motility of airway epithelial cells. Pathol Int, 2009. 59(1):
28-37.
39. Okudela, K., Yazawa, T., Ishii, J., Woo, T., Mitsui, H., Bunai, T.,
Sakaeda, M., Shimoyamada, H., Sato, H., Tajiri, M., Ogawa, N., Masuda, M.,
Sugimura, H., and Kitamura, H., Down-Regulation of FXYD3 Expression in
Human Lung Cancers. Its Mechanism and Potential Role in Carcinogenesis.
Am J Pathol, 2009. 175(6): 2646-56.
40. Nishino, M., Sugimoto, M., Kodaira, C., Yamade, M., Shirai, N.,
Ikuma, M., Tanaka, T., Sugimura, H., Hishida, A., and Furuta, T.,
Relationship Between Low-Dose Aspirin-Induced Gastric Mucosal Injury and
Intragastric pH in Healthy Volunteers. Dig Dis Sci, 2009.
41. Midorikawa, Y., Yamamoto, S., Tsuji, S., Kamimura, N., Ishikawa,
S., Igarashi, H., Makuuchi, M., Kokudo, N., Sugimura, H., and Aburatani,
H., Allelic imbalances and homozygous deletion on 8p23.2 for stepwise
progression of hepatocarcinogenesis. Hepatology, 2009. 49(2): 513-22.
42. Iwaizumi, M., Shinmura, K., Mori, H., Yamada, H., Suzuki, M.,
Kitayama, Y., Igarashi, H., Nakamura, T., Suzuki, H., Watanabe, Y., Hishida,
A., Ikuma, M., and Sugimura, H., Human Sgo1 downregulation leads to
chromosomal instability in colorectal cancer. Gut, 2009. 58(2): 249-60.
43. Goto, M., Shinmura, K., Igarashi, H., Kobayashi, M., Konno, H.,
Yamada, H., Iwaizumi, M., Kageyama, S., Tsuneyoshi, T., Tsugane, S., and
Sugimura, H., Altered expression of the human base excision repair gene
NTH1 in gastric cancer. Carcinogenesis, 2009. 30(8): 1345-52.
44. Dong, Y., Wang, J., Sheng, Z., Li, G., Ma, H., Wang, X., Zhang, R.,
Lu, G., Hu, Q., Sugimura, H., and Zhou, X., Downregulation of EphA1 in
colorectal carcinomas correlates with invasion and metastasis. Mod Pathol,
2009. 22(1): 151-60.
45. Yamagata, N., Furuno, K., Sonoda, M., Sugimura, H., and Yamamoto,
K., Stomach cancer-derived del223V-226L mutation of the STCH gene causes
loss of sensitization to TRAIL-mediated apoptosis. Biochem Biophys Res
Commun, 2008. 376(3): 499-503.
46. Torisu, Y., Watanabe, A., Nonaka, A., Midorikawa, Y., Makuuchi, M.,
Shimamura, T., Sugimura, H., Niida, A., Akiyama, T., Iwanari, H., Kodama,
T., Zeniya, M., and Aburatani, H., Human homolog of NOTUM, overexpressed
in hepatocellular carcinoma, is regulated transcriptionally by
beta-catenin/TCF. Cancer Sci, 2008. 99(6): 1139-46.
47. Tao, H., Shinmura, K., Suzuki, M., Kono, S., Mibu, R., Tanaka, M.,
Kakeji, Y., Maehara, Y., Okamura, T., Ikejiri, K., Futami, K., Yasunami,
Y., Maekawa, T., Takenaka, K., Ichimiya, H., Imaizumi, N., and Sugimura,
H., Association between genetic polymorphisms of the base excision repair
gene MUTYH and increased colorectal cancer risk in a Japanese population.
Cancer Sci, 2008. 99(2): 355-60.
48. Suzuki, M., Kageyama, S., Shinmura, K., Okudela, K., Bunai, T.,
Nagura, K., Igarashi, H., Kiyose, S., Mori, H., Tao, H., Goto, M., Takamochi,
K., Mochizuki, T., Suzuki, K., Ohashi, R., Ogawa, H., Yamada, T., Niwa,
H., Tsuneyoshi, T., and Sugimura, H., Inverse relationship between the
length of the EGFR CA repeat polymorphism in lung carcinoma and protein
expression of EGFR in the carcinoma. J Surg Oncol, 2008. 98(6): 457-61.
49. Suzuki, A., Suzuki, S., Sakaguchi, T., Oishi, K., Fukumoto, K., Ota,
S., Inaba, K., Takehara, Y., Sugimura, H., Uchiyama, T., and Konno, H.,
Colonic fistula associated with severe acute pancreatitis: report of two
cases. Surg Today, 2008. 38(2): 178-83.
50. Sugimura, H., Detection of chromosome changes in pathology
archives: an application of microwave-assisted fluorescence in situ
hybridization to human carcinogenesis studies. Carcinogenesis, 2008.
29(4): 681-7.
51. Sugimura, H., [Familial aggregation of gastric cancer]. Gan To
Kagaku Ryoho, 2008. 35(4): 551-6.
52. Sugimoto, M., Furuta, T., Shirai, N., Kodaira, C., Nishino, M.,
Yamade, M., Ikuma, M., Sugimura, H., Ishizaki, T., and Hishida, A., MDR1
C3435T polymorphism has no influence on developing Helicobacter pylori
infection-related gastric cancer and peptic ulcer in Japanese. Life Sci,
2008. 7-883(7-8): 301-4.
53. Sugimoto, M., Furuta, T., Kodaira, C., Nishino, M., Yamade, M.,
Ikuma, M., Sugimura, H., and Hishida, A., Polymorphisms of matrix
metalloproteinase-7 and chymase are associated with susceptibility to and
progression of gastric cancer in Japan. J Gastroenterol, 2008. 43(10):
751-61.
54. Shinmura, K., Suzuki, M., Yamada, H., Tao, H., Goto, M., Kamo, T.,
Nagura, K., Kageyama, S., Kato, M., Ogawa, S., Maekawa, M., Takamochi, K.,
Suzuki, K., Nakamura, T., and Sugimura, H., Characterization of
adenocarcinoma of the lung in a familial adenomatous polyposis patient.
Pathol Int, 2008. 58(11): 706-12.
55. Shinmura, K., Kageyama, S., Tao, H., Bunai, T., Suzuki, M., Kamo,
T., Takamochi, K., Suzuki, K., Tanahashi, M., Niwa, H., Ogawa, H., and
Sugimura, H., EML4-ALK fusion transcripts, but no NPM-, TPM3-, CLTC-, ATIC-,
or TFG-ALK fusion transcripts, in non-small cell lung carcinomas. Lung
Cancer, 2008. 61(2): 163-9.
56. Shinmura, K., Iwaizumi, M., Igarashi, H., Nagura, K., Yamada, H.,
Suzuki, M., Fukasawa, K., and Sugimura, H., Induction of centrosome
amplification and chromosome instability in p53-deficient lung cancer
cells exposed to benzo[a]pyrene diol epoxide (B[a]PDE). J Pathol, 2008.
216(3): 365-74.
57. Sheng, Z., Wang, J., Dong, Y., Ma, H., Zhou, H., Sugimura, H., Lu,
G., and Zhou, X., EphB1 is underexpressed in poorly differentiated
colorectal cancers. Pathobiology, 2008. 75(5): 274-80.
58. Sakamoto, H., Yoshimura, K., Saeki, N., Katai, H., Shimoda, T.,
Matsuno, Y., Saito, D., Sugimura, H., Tanioka, F., Kato, S., Matsukura,
N., Matsuda, N., Nakamura, T., Hyodo, I., Nishina, T., Yasui, W., Hirose,
H., Hayashi, M., Toshiro, E., Ohnami, S., Sekine, A., Sato, Y., Totsuka,
H., Ando, M., Takemura, R., Takahashi, Y., Ohdaira, M., Aoki, K., Honmyo,
I., Chiku, S., Aoyagi, K., Sasaki, H., Yanagihara, K., Yoon, K.A., Kook,
M.C., Lee, Y.S., Park, S.R., Kim, C.G., Choi, I.J., Yoshida, T., Nakamura,
Y., and Hirohashi, S., Genetic variation in PSCA is associated with
susceptibility to diffuse-type gastric cancer. Nat Genet, 2008. 40(6):
730-40.
59. Ohnami, S., Sato, Y., Yoshimura, K., Sakamoto, H., Aoki, K., Ueno,
H., Ikeda, M., Morizane, C., Shimada, K., Sakamoto, Y., Esaki, M., Saito,
I., Hirose, H., Saito, D., Sugimura, H., Kosuge, T., Okusaka, T., and
Yoshida, T., His595Tyr polymorphism in the methionine synthase reductase
(MTRR) gene is associated with pancreatic cancer risk. Gastroenterology,
2008. 135(2): 477-88.
60. Nakayama, R., Sato, Y., Masutani, M., Ogino, H., Nakatani, F.,
Chuman, H., Beppu, Y., Morioka, H., Yabe, H., Hirose, H., Sugimura, H.,
Sakamoto, H., Ohta, T., Toyama, Y., Yoshida, T., and Kawai, A., Association
of a missense single nucleotide polymorphism, Cys1367Arg of the WRN gene,
with the risk of bone and soft tissue sarcomas in Japan. Cancer Sci, 2008.
99(2): 333-9.
61. Mori, H., Nagata, M., Nishijima, N., Nagura, K., Igarashi, H.,
Hamazaki, M., Ozono, S., and Sugimura, H., Malignant pheochromocytoma in
a young adult forming the structure simulating Homer Wright rosette:
differentiation from neuroblastoma on repeating fluorescence in situ
hybridization. Pathol Int, 2008. 58(8): 518-23.
62. Lee, K.M., Kang, D., Clapper, M.L., Ingelman-Sundberg, M.,
Ono-Kihara, M., Kiyohara, C., Min, S., Lan, Q., Le Marchand, L., Lin, P.,
Lung, M.L., Pinarbasi, H., Pisani, P., Srivatanakul, P., Seow, A., Sugimura,
H., Tokudome, S., Yokota, J., and Taioli, E., CYP1A1, GSTM1, and GSTT1
polymorphisms, smoking, and lung cancer risk in a pooled analysis among
Asian populations. Cancer Epidemiol Biomarkers Prev, 2008. 17(5): 1120-6.
63. Kasami, M., Uematsu, T., Honda, M., Yabuzaki, T., Sanuki, J., Uchida,
Y., and Sugimura, H., Comparison of estrogen receptor, progesterone
receptor and Her-2 status in breast cancer pre- and post-neoadjuvant
chemotherapy. Breast, 2008.
64. Kageyama, S., Shinmura, K., Yamamoto, H., Goto, M., Suzuki, K.,
Tanioka, F., Tsuneyoshi, T., and Sugimura, H., Fluorescence-labeled
methylation-sensitive amplified fragment length polymorphism (FL-MS-AFLP)
analysis for quantitative determination of DNA methylation and
demethylation status. Jpn J Clin Oncol, 2008. 38(4): 317-22.
65. Goto, M., Shinmura, K., Yamada, H., Tsuneyoshi, T., and Sugimura,
H., OGG1, MYH and MTH1 gene variants identified in gastric cancer patients
exhibiting both 8-hydroxy-2'-deoxyguanosine accumulation and low
inflammatory cell infiltration in their gastric mucosa. J Genet, 2008.
87(2): 181-6.
66. Arai, Y., Tsuchida, T., Tanioka, F., Sugimura, H., Watanabe, C.,
Hongo, T., and Tsutsui, Y., Congenital anaplastic astrocytoma
differentiated into pilocytic astrocytoma: an autopsy case. Neuropathology,
2008. 28(4): 433-9.
67. Yamada, H., Shinmura, K., Okudela, K., Goto, M., Suzuki, M., Kuriki,
K., Tsuneyoshi, T., and Sugimura, H., Identification and characterization
of a novel germ line p53 mutation in familial gastric cancer in the Japanese
population. Carcinogenesis, 2007. 28(9): 2013-8.
68. Yamada, H., Shinmura, K., Ikeda, S., Tao, H., Otani, T., Hanaoka,
T., Tsuneyoshi, T., Tsugane, S., and Sugimura, H., Association between CDH1
haplotypes and gastric cancer risk in a Japanese population. Scand J
Gastroenterol, 2007. 42(12): 1479-85.
69. Watanabe, Y., Shibata, K., Sugimura, H., and Maekawa, M.,
p53-dependent change in replication timing of the human genome. Biochem
Biophys Res Commun, 2007. 364(2): 289-93.
70. Wang, J.D., Dong, Y.C., Sheng, Z., Ma, H.H., Li, G.L., Wang, X.L.,
Lu, G.M., Sugimura, H., Jin, J., and Zhou, X.J., Loss of expression of EphB1
protein in gastric carcinoma associated with invasion and metastasis.
Oncology, 2007. 73(3-4): 238-45.
71. Wang, J., Li, G., Ma, H., Bao, Y., Wang, X., Zhou, H., Sheng, Z.,
Sugimura, H., Jin, J., and Zhou, X., Differential expression of EphA7
receptor tyrosine kinase in gastric carcinoma. Hum Pathol, 2007. 38(11):
1649-56.
72. Takamochi, K., Suzuki, K., Sugimura, H., Funai, K., Mori, H., Bashar,
A.H., and Kazui, T., Surgical resection after gefitinib treatment in
patients with lung adenocarcinoma harboring epidermal growth factor
receptor gene mutation. Lung Cancer, 2007. 58(1): 149-55.
73. Suzuki, H., Sugimura, H., and Hashimoto, K., Overexpression of heat
shock protein 27 is associated with good prognosis in the patient with oral
squamous cell carcinoma. Br J Oral Maxillofac Surg, 2007. 45(2): 123-9.
74. Sugimoto, M., Furuta, T., Shirai, N., Nakamura, A., Xiao, F.,
Kajimura, M., Sugimura, H., and Hishida, A., Different effects of
polymorphisms of tumor necrosis factor-alpha and interleukin-1 beta on
development of peptic ulcer and gastric cancer. J Gastroenterol Hepatol,
2007. 22(1): 51-9.
75. Sugimoto, M., Furuta, T., Shirai, N., Nakamura, A., Kajimura, M.,
Sugimura, H., and Hishida, A., Effects of interleukin-10 gene polymorphism
on the development of gastric cancer and peptic ulcer in Japanese subjects.
J Gastroenterol Hepatol, 2007. 22(9): 1443-9.
76. Sugimoto, M., Furuta, T., Shirai, N., Kodaira, C., Nishino, M.,
Ikuma, M., Sugimura, H., and Hishida, A., Role of angiotensinogen gene
polymorphism on Helicobacter pylori infection-related gastric cancer risk
in Japanese. Carcinogenesis, 2007. 28(9): 2036-40.
77. Seike, M., Yanaihara, N., Bowman, E.D., Zanetti, K.A., Budhu, A.,
Kumamoto, K., Mechanic, L.E., Matsumoto, S., Yokota, J., Shibata, T.,
Sugimura, H., Gemma, A., Kudoh, S., Wang, X.W., and Harris, C.C., Use of
a cytokine gene expression signature in lung adenocarcinoma and the
surrounding tissue as a prognostic classifier. J Natl Cancer Inst, 2007.
99(16): 1257-69.
78. Okudela, K., Suzuki, M., Kageyama, S., Bunai, T., Nagura, K.,
Igarashi, H., Takamochi, K., Suzuki, K., Yamada, T., Niwa, H., Ohashi, R.,
Ogawa, H., Mori, H., Kitamura, H., Kaneko, T., Tsuneyoshi, T., and Sugimura,
H., PIK3CA mutation and amplification in human lung cancer. Pathol Int,
2007. 57(10): 664-71.
79. Kikuchi, H., Yamamoto, M., Hiramatsu, Y., Baba, M., Ohta, M., Kamiya,
K., Tanaka, T., Suzuki, S., Sugimura, H., Kitagawa, M., Kanai, T., Kitayama,
Y., Kanda, T., Nishikura, K., and Konno, H., Effect of loss of
heterozygosity of the c-kit gene on prognosis after hepatectomy for
metastatic liver gastrointestinal stromal tumors. Cancer Sci, 2007.
98(11): 1734-9.
80. Ikeda, M., Hirabayashi, S., Fujiwara, N., Mori, H., Kawata, A., Iida,
J., Bao, Y., Sato, Y., Iida, T., Sugimura, H., and Hata, Y., Ras-association
domain family protein 6 induces apoptosis via both caspase-dependent and
caspase-independent pathways. Exp Cell Res, 2007. 313(7): 1484-95.
81. Gao, C.M., Takezaki, T., Wu, J.Z., Chen, M.B., Liu, Y.T., Ding, J.H.,
Sugimura, H., Cao, J., Hamajima, N., and Tajima, K., CYP2E1 Rsa I
polymorphism impacts on risk of colorectal cancer association with smoking
and alcohol drinking. World J Gastroenterol, 2007. 13(43): 5725-30.
82. Yamashita, K., Igarashi, H., Kitayama, Y., Ozawa, T., Kiyose, S.,
Konno, H., Kazui, T., Ishikawa, S., Aburatani, H., Tanioka, F., Suzuki,
M., and Sugimura, H., Chromosomal numerical abnormality profiles of
gastrointestinal stromal tumors. Jpn J Clin Oncol, 2006. 36(2): 85-92.
83. Suzuki, H., Sugimura, H., and Hashimoto, K., p16INK4A in oral
squamous cell carcinomas--a correlation with biological behaviors:
immunohistochemical and FISH analysis. J Oral Maxillofac Surg, 2006.
64(11): 1617-23.
84. Sugimoto, M., Furuta, T., Shirai, N., Ikuma, M., Sugimura, H., and
Hishida, A., Influences of chymase and angiotensin I-converting enzyme gene
polymorphisms on gastric cancer risks in Japan. Cancer Epidemiol Biomarkers
Prev, 2006. 15(10): 1929-34.
85. Sano, T., Kitayama, Y., Igarashi, H., Suzuki, M., Tanioka, F., Chida,
K., Okudela, K., and Sugimura, H., Chromosomal numerical abnormalities in
early stage lung adenocarcinoma. Pathol Int, 2006. 56(3): 117-25.
86. Raimondi, S., Paracchini, V., Autrup, H., Barros-Dios, J.M.,
Benhamou, S., Boffetta, P., Cote, M.L., Dialyna, I.A., Dolzan, V.,
Filiberti, R., Garte, S., Hirvonen, A., Husgafvel-Pursiainen, K.,
Imyanitov, E.N., Kalina, I., Kang, D., Kiyohara, C., Kohno, T., Kremers,
P., Lan, Q., London, S., Povey, A.C., Rannug, A., Reszka, E., Risch, A.,
Romkes, M., Schneider, J., Seow, A., Shields, P.G., Sobti, R.C., Sorensen,
M., Spinola, M., Spitz, M.R., Strange, R.C., Stucker, I., Sugimura, H.,
To-Figueras, J., Tokudome, S., Yang, P., Yuan, J.M., Warholm, M., and Taioli,
E., Meta- and pooled analysis of GSTT1 and lung cancer: a HuGE-GSEC review.
Am J Epidemiol, 2006. 164(11): 1027-42.
87. Miwa, S., Uchida, C., Kitagawa, K., Hattori, T., Oda, T., Sugimura,
H., Yasuda, H., Nakamura, H., Chida, K., and Kitagawa, M., Mdm2-mediated
pRB downregulation is involved in carcinogenesis in a p53-independent
manner. Biochem Biophys Res Commun, 2006. 340(1): 54-61.
88. Midorikawa, Y., Yamamoto, S., Ishikawa, S., Kamimura, N., Igarashi,
H., Sugimura, H., Makuuchi, M., and Aburatani, H., Molecular karyotyping
of human hepatocellular carcinoma using single-nucleotide polymorphism
arrays. Oncogene, 2006. 25(40): 5581-90.
89. Kitayama, Y., Igarashi, H., Kozu, T., Nagura, K., Ohashi, Y., and
Sugimura, H., Repeated fluorescence in situ hybridization by a
microwave-enhanced protocol. Pathol Int, 2006. 56(9): 490-3.
90. Kikuchi, H., Yamashita, K., Kawabata, T., Yamamoto, M., Hiramatsu,
Y., Kondo, K., Baba, M., Ohta, M., Kamiya, K., Tanaka, T., Suzuki, S.,
Kitagawa, K., Kitagawa, M., Sugimura, H., and Konno, H.,
Immunohistochemical and genetic features of gastric and metastatic liver
gastrointestinal stromal tumors: sequential analyses. Cancer Sci, 2006.
97(2): 127-32.
91. Kikuchi, H., Yamamoto, M., Hiramatsu, Y., Baba, M., Ohta, M., Kamiya,
K., Tanaka, T., Suzuki, S., Sugimura, H., and Konno, H., [Manifestation
of liver metastasis 13 years after gastrectomy for gastric GIST]. Nippon
Shokakibyo Gakkai Zasshi, 2006. 103(9): 1055-60.
92. Kanaly, R.A., Hanaoka, T., Sugimura, H., Toda, H., Matsui, S., and
Matsuda, T., Development of the adductome approach to detect DNA damage
in humans. Antioxid Redox Signal, 2006. 8(5-6): 993-1001.
93. Yamada, H., Shinmura, K., Tsuneyoshi, T., and Sugimura, H., Effect
of splice-site polymorphisms of the TMPRSS4, NPHP4 and ORCTL4 genes on their
mRNA expression. J Genet, 2005. 84(2): 131-6.
94. Wang, J., Kataoka, H., Suzuki, M., Sato, N., Nakamura, R., Tao, H.,
Maruyama, K., Isogaki, J., Kanaoka, S., Ihara, M., Tanaka, M., Kanamori,
M., Nakamura, T., Shinmura, K., and Sugimura, H., Downregulation of EphA7
by hypermethylation in colorectal cancer. Oncogene, 2005. 24(36):
5637-47.
95. Uchida, C., Miwa, S., Kitagawa, K., Hattori, T., Isobe, T., Otani,
S., Oda, T., Sugimura, H., Kamijo, T., Ookawa, K., Yasuda, H., and Kitagawa,
M., Enhanced Mdm2 activity inhibits pRB function via ubiquitin-dependent
degradation. EMBO J, 2005. 24(1): 160-9.
96. Sugimoto, M., Furuta, T., Shirai, N., Nakamura, A., Kajimura, M.,
Sugimura, H., Hishida, A., and Ishizaki, T., Poor metabolizer genotype
status of CYP2C19 is a risk factor for developing gastric cancer in Japanese
patients with Helicobacter pylori infection. Aliment Pharmacol Ther, 2005.
22(10): 1033-40.
97. Shinmura, K., Goto, M., Tao, H., Shimizu, S., Otsuki, Y., Kobayashi,
H., Ushida, S., Suzuki, K., Tsuneyoshi, T., and Sugimura, H., A novel STK11
germline mutation in two siblings with Peutz-Jeghers syndrome complicated
by primary gastric cancer. Clin Genet, 2005. 67(1): 81-6.
98. Shimamura, T., Ito, H., Shibahara, J., Watanabe, A., Hippo, Y.,
Taniguchi, H., Chen, Y., Kashima, T., Ohtomo, T., Tanioka, F., Iwanari,
H., Kodama, T., Kazui, T., Sugimura, H., Fukayama, M., and Aburatani, H.,
Overexpression of MUC13 is associated with intestinal-type gastric cancer.
Cancer Sci, 2005. 96(5): 265-73.
99. Raimondi, S., Boffetta, P., Anttila, S., Brockmoller, J.,
Butkiewicz, D., Cascorbi, I., Clapper, M.L., Dragani, T.A., Garte, S., Gsur,
A., Haidinger, G., Hirvonen, A., Ingelman-Sundberg, M., Kalina, I., Lan,
Q., Leoni, V.P., Le Marchand, L., London, S.J., Neri, M., Povey, A.C.,
Rannug, A., Reszka, E., Ryberg, D., Risch, A., Romkes, M., Ruano-Ravina,
A., Schoket, B., Spinola, M., Sugimura, H., Wu, X., and Taioli, E.,
Metabolic gene polymorphisms and lung cancer risk in non-smokers. An update
of the GSEC study. Mutat Res, 2005. 592(1-2): 45-57.
100. Nakamura, R., Kataoka, H., Sato, N., Kanamori, M., Ihara, M.,
Igarashi, H., Ravshanov, S., Wang, Y.J., Li, Z.Y., Shimamura, T., Kobayashi,
T., Konno, H., Shinmura, K., Tanaka, M., and Sugimura, H., EPHA2/EFNA1
expression in human gastric cancer. Cancer Sci, 2005. 96(1): 42-7.
101. Maekawa, M., Taniguchi, T., Uramoto, T., Higashi, H., Horii, T.,
Takeshita, A., Sugimura, H., and Kanamori, M., Pilot study of arbitrarily
primed PCR-single stranded DNA conformation polymorphism analysis for
screening genetic polymorphisms related to specific phenotypes. Clin Chim
Acta, 2005. 355(1-2): 181-4.
102. Kitayama, Y. and Sugimura, H., Nonrandom chromosomal numerical
abnormality as a new molecular cytogenetic tumor marker--a retrospective
study of 60 gastric cancer cases. Rinsho Byori, 2005. 53(10): 881-6.
103. Igarashi, H., Yamashita, K., Suzuki, M., Kitayama, Y., Isogaki, J.,
Maruyama, K., Sunayama, K., Tsuda, H., Ozawa, T., Kiyose, S., and Sugimura,
H., Simultaneous imaging of membrane antigen and the corresponding
chromosomal locus in pathology archives. Pathol Int, 2005. 55(12): 753-6.
104. Aoki, M., Yamamoto, K., Ohyama, S., Yamamura, Y., Takenoshita, S.,
Sugano, K., Minamoto, T., Kitajima, M., Sugimura, H., Shimada, S., Noshiro,
H., Hiratsuka, M., Sairenji, M., Ninomiya, I., Yano, M., Uesaka, K., Matsuno,
S., Maehara, Y., Aikou, T., and Sasazuki, T., A genetic variant in the gene
encoding the stress70 protein chaperone family member STCH is associated
with gastric cancer in the Japanese population. Biochem Biophys Res Commun,
2005. 335(2): 566-74.
105. Aoki, M., Yamamoto, K., Noshiro, H., Sakai, K., Yokota, J., Kohno,
T., Tokino, T., Ishida, S., Ohyama, S., Ninomiya, I., Uesaka, K., Kitajima,
M., Shimada, S., Matsuno, S., Yano, M., Hiratsuka, M., Sugimura, H., Itoh,
F., Minamoto, T., Maehara, Y., Takenoshita, S., Aikou, T., Katai, H.,
Yoshimura, K., Takahashi, T., Akagi, K., Sairenji, M., Yamamura, Y., and
Sasazuki, T., A full genome scan for gastric cancer. J Med Genet, 2005.
42(1): 83-7.
106. Watanabe, Y., Ikemura, T., and Sugimura, H., Amplicons on human
chromosome 11q are located in the early/late-switch regions of replication
timing. Genomics, 2004. 84(5): 796-805.
107. Tao, H., Shinmura, K., Hanaoka, T., Natsukawa, S., Shaura, K.,
Koizumi, Y., Kasuga, Y., Ozawa, T., Tsujinaka, T., Li, Z., Yamaguchi, S.,
Yokota, J., Sugimura, H., and Tsugane, S., A novel splice-site variant of
the base excision repair gene MYH is associated with production of an
aberrant mRNA transcript encoding a truncated MYH protein not localized
in the nucleus. Carcinogenesis, 2004. 25(10): 1859-66.
108. Tanaka, M., Ohashi, R., Nakamura, R., Shinmura, K., Kamo, T., Sakai,
R., and Sugimura, H., Tiam1 mediates neurite outgrowth induced by ephrin-B1
and EphA2. EMBO J, 2004. 23(5): 1075-88.
109. Smits, K.M., Benhamou, S., Garte, S., Weijenberg, M.P., Alamanos,
Y., Ambrosone, C., Autrup, H., Autrup, J.L., Baranova, H., Bathum, L.,
Boffetta, P., Bouchardy, C., Brockmoller, J., Butkiewicz, D., Cascorbi,
I., Clapper, M.L., Coutelle, C., Daly, A.K., Muzi, G., Dolzan, V., Duzhak,
T.G., Farker, K., Golka, K., Haugen, A., Hein, D.W., Hildesheim, A.,
Hirvonen, A., Hsieh, L.L., Ingelman-Sundberg, M., Kalina, I., Kang, D.,
Katoh, T., Kihara, M., Ono-Kihara, M., Kim, H., Kiyohara, C., Kremers, P.,
Lazarus, P., Le Marchand, L., Lechner, M.C., London, S., Manni, J.J.,
Maugard, C.M., Morgan, G.J., Morita, S., Nazar-Stewart, V., Kristensen,
V.N., Oda, Y., Parl, F.F., Peters, W.H., Rannug, A., Rebbeck, T., Pinto,
L.F., Risch, A., Romkes, M., Salagovic, J., Schoket, B., Seidegard, J.,
Shields, P.G., Sim, E., Sinnett, D., Strange, R.C., Stucker, I., Sugimura,
H., To-Figueras, J., Vineis, P., Yu, M.C., Zheng, W., Pedotti, P., and
Taioli, E., Association of metabolic gene polymorphisms with tobacco
consumption in healthy controls. Int J Cancer, 2004. 110(2): 266-70.
110. Shinmura, K., Tao, H., Yamada, H., Kataoka, H., Sanjar, R., Wang,
J., Yoshimura, K., and Sugimura, H., Splice-site genetic polymorphism of
the human kallikrein 12 (KLK12) gene correlates with no substantial
expression of KLK12 protein having serine protease activity. Hum Mutat,
2004. 24(3): 273-4.
111. Shinmura, K., Tao, H., Goto, M., Igarashi, H., Taniguchi, T.,
Maekawa, M., Takezaki, T., and Sugimura, H., Inactivating mutations of the
human base excision repair gene NEIL1 in gastric cancer. Carcinogenesis,
2004. 25(12): 2311-7.
112. Mori, H., Hirabayashi, S., Shirasawa, M., Sugimura, H., and Hata,
Y., JAM4 enhances hepatocyte growth factor-mediated branching and
scattering of Madin-Darby canine kidney cells. Genes Cells, 2004. 9(9):
811-9.
113. Maekawa, M., Taniguchi, T., Higashi, H., Sugimura, H., Sugano, K.,
and Kanno, T., Methylation of mitochondrial DNA is not a useful marker for
cancer detection. Clin Chem, 2004. 50(8): 1480-1.
114. Maekawa, M., Nagaoka, T., Taniguchi, T., Higashi, H., Sugimura, H.,
Sugano, K., Yonekawa, H., Satoh, T., Horii, T., Shirai, N., Takeshita, A.,
and Kanno, T., Three-dimensional microarray compared with
PCR-single-strand conformation polymorphism analysis/DNA sequencing for
mutation analysis of K-ras codons 12 and 13. Clin Chem, 2004. 50(8):
1322-7.
115. Kobayashi, K., Nishioka, M., Kohno, T., Nakamoto, M., Maeshima, A.,
Aoyagi, K., Sasaki, H., Takenoshita, S., Sugimura, H., and Yokota, J.,
Identification of genes whose expression is upregulated in lung
adenocarcinoma cells in comparison with type II alveolar cells and
bronchiolar epithelial cells in vivo. Oncogene, 2004. 23(17): 3089-96.
116. Kikuchi, H., Konno, H., Kamiya, K., Baba, M., Ohta, M., Kondo, K.,
Hiramatsu, Y., Yamamoto, M., Tanaka, T., Sugimura, H., Ohashi, M., Kanda,
T., and Nakamura, S., [Two cases of postoperative recurrence of gastric
GIST treated by imatinib]. Gan To Kagaku Ryoho, 2004. 31(10): 1569-73.
117. Kataoka, H., Igarashi, H., Kanamori, M., Ihara, M., Wang, J.D., Wang,
Y.J., Li, Z.Y., Shimamura, T., Kobayashi, T., Maruyama, K., Nakamura, T.,
Arai, H., Kajimura, M., Hanai, H., Tanaka, M., and Sugimura, H., Correlation
of EPHA2 overexpression with high microvessel count in human primary
colorectal cancer. Cancer Sci, 2004. 95(2): 136-41.
118. Kanaoka, S., Yoshida, K., Miura, N., Sugimura, H., and Kajimura,
M., Potential usefulness of detecting cyclooxygenase 2 messenger RNA in
feces for colorectal cancer screening. Gastroenterology, 2004. 127(2):
422-7.
119. Hiramatsu, Y., Konno, H., Kamiya, K., Baba, M., Ohta, M., Kondo,
K., Yamamoto, M., Kikuchi, H., Tanaka, T., Sugimura, H., and Nakamura, S.,
[A case of gastric GIST treated preoperatively by imatinib mesylate]. Gan
To Kagaku Ryoho, 2004. 31(8): 1219-23.
120. Gao, C.M., Takezaki, T., Wu, J.Z., Liu, Y.T., Ding, J.H., Li, S.P.,
Su, P., Hu, X., Kai, H.T., Li, Z.Y., Matsuo, K., Hamajima, N., Sugimura,
H., and Tajima, K., Polymorphisms in thymidylate synthase and
methylenetetrahydrofolate reductase genes and the susceptibility to
esophageal and stomach cancer with smoking. Asian Pac J Cancer Prev, 2004.
5(2): 133-8.
121. Furuta, T., Shirai, N., Xiao, F., El-Omar, E.M., Rabkin, C.S.,
Sugimura, H., Ishizaki, T., and Ohashi, K., Polymorphism of
interleukin-1beta affects the eradication rates of Helicobacter pylori by
triple therapy. Clin Gastroenterol Hepatol, 2004. 2(1): 22-30.
122. Wang, Y., Song, J.P., Ikeda, M., Shinmura, K., Yokota, J., and
Sugimura, H., Ile-Leu substitution (I415L) in germline E-cadherin gene
(CDH1) in Japanese familial gastric cancer. Jpn J Clin Oncol, 2003. 33(1):
17-20.
123. Vineis, P., Veglia, F., Benhamou, S., Butkiewicz, D., Cascorbi, I.,
Clapper, M.L., Dolzan, V., Haugen, A., Hirvonen, A., Ingelman-Sundberg,
M., Kihara, M., Kiyohara, C., Kremers, P., Le Marchand, L., Ohshima, S.,
Pastorelli, R., Rannug, A., Romkes, M., Schoket, B., Shields, P., Strange,
R.C., Stucker, I., Sugimura, H., Garte, S., Gaspari, L., and Taioli, E.,
CYP1A1 T3801 C polymorphism and lung cancer: a pooled analysis of 2451 cases
and 3358 controls. Int J Cancer, 2003. 104(5): 650-7.
124. Ueki, T., Tanaka, M., Yamashita, K., Mikawa, S., Qiu, Z., Maragakis,
N.J., Hevner, R.F., Miura, N., Sugimura, H., and Sato, K., A novel secretory
factor, Neurogenesin-1, provides neurogenic environmental cues for neural
stem cells in the adult hippocampus. J Neurosci, 2003. 23(37): 11732-40.
125. Tozawa, K., Hanai, H., Sugimoto, K., Baba, S., Sugimura, H., Aoshi,
T., Uchijima, M., Nagata, T., and Koide, Y., Evidence for the critical role
of interleukin-12 but not interferon-gamma in the pathogenesis of
experimental colitis in mice. J Gastroenterol Hepatol, 2003. 18(5):
578-87.
126. Tanioka, F., Tamashima, S., Shimizu, S., Kobayashi, H., Kobayashi,
Y., and Sugimura, H., A case of primary plasma cell leukemia with hairy-cell
morphology and lambda-type Bence-Jones protein. Immunohistochemical and
molecular analysis. Jpn J Clin Oncol, 2003. 33(5): 232-7.
127. Tanaka, M., Kamo, T., Ota, S., and Sugimura, H., Association of
Dishevelled with Eph tyrosine kinase receptor and ephrin mediates cell
repulsion. EMBO J, 2003. 22(4): 847-58.
128. Otsuki, Y., Tanaka, M., Kamo, T., Kitanaka, C., Kuchino, Y., and
Sugimura, H., Guanine nucleotide exchange factor, Tiam1, directly binds
to c-Myc and interferes with c-Myc-mediated apoptosis in rat-1 fibroblasts.
J Biol Chem, 2003. 278(7): 5132-40.
129. Nakamura, R. and Sugimura, H., [Molecular biology of colorectal
cancer: The cell cycle and its regulation]. Nippon Rinsho, 2003. 61 Suppl
7: 91-4.
130. Nakamura, R., Song, J.P., Isogaki, J., Kitayama, Y., and Sugimura,
H., Multiple (multicentric and multifocal) cancers in the ipsilateral
breast with different histologies: profiles of chromosomal numerical
abnormality. Jpn J Clin Oncol, 2003. 33(9): 463-9.
131. Maekawa, M., Taniguchi, T., Tatebayashi, C., Horii, T., Takeshita,
A., Sugimura, H., Sugano, K., Yonekawa, H., Nagaoka, T., and Kanno, T.,
[Basic studies on mutation analysis of K-ras codon 12 by use of
three-dimensional microarray system]. Rinsho Byori, 2003. 51(4): 306-12.
132. Maekawa, M., Taniguchi, T., Ishikawa, J., Sugimura, H., Sugano, K.,
and Kanno, T., Promoter hypermethylation in cancer silences LDHB,
eliminating lactate dehydrogenase isoenzymes 1-4. Clin Chem, 2003. 49(9):
1518-20.
133. Li, Z., Tanaka, M., Kataoka, H., Nakamura, R., Sanjar, R., Shinmura,
K., and Sugimura, H., EphA2 up-regulation induced by deoxycholic acid in
human colon carcinoma cells, an involvement of extracellular
signal-regulated kinase and p53-independence. J Cancer Res Clin Oncol, 2003.
129(12): 703-8.
134. Le Marchand, L., Guo, C., Benhamou, S., Bouchardy, C., Cascorbi,
I., Clapper, M.L., Garte, S., Haugen, A., Ingelman-Sundberg, M., Kihara,
M., Rannug, A., Ryberg, D., Stucker, I., Sugimura, H., and Taioli, E.,
Pooled analysis of the CYP1A1 exon 7 polymorphism and lung cancer (United
States). Cancer Causes Control, 2003. 14(4): 339-46.
135. Kitayama, Y., Igarashi, H., Watanabe, F., Maruyama, Y., Kanamori,
M., and Sugimura, H., Nonrandom chromosomal numerical abnormality
predicting prognosis of gastric cancer: a retrospective study of 51 cases
using pathology archives. Lab Invest, 2003. 83(9): 1311-20.
136. Yokota, N., Nishizawa, S., Ohta, S., Date, H., Sugimura, H., Namba,
H., and Maekawa, M., Role of Wnt pathway in medulloblastoma oncogenesis.
Int J Cancer, 2002. 101(2): 198-201.
137. Wang, Y., Ota, S., Kataoka, H., Kanamori, M., Li, Z., Band, H.,
Tanaka, M., and Sugimura, H., Negative regulation of EphA2 receptor by Cbl.
Biochem Biophys Res Commun, 2002. 296(1): 214-20.
138. Takezaki, T., Gao, C.M., Wu, J.Z., Li, Z.Y., Wang, J.D., Ding, J.H.,
Liu, Y.T., Hu, X., Xu, T.L., Tajima, K., and Sugimura, H., hOGG1 Ser(326)Cys
polymorphism and modification by environmental factors of stomach cancer
risk in Chinese. Int J Cancer, 2002. 99(4): 624-7.
139. Sunaga, N., Kohno, T., Yanagitani, N., Sugimura, H., Kunitoh, H.,
Tamura, T., Takei, Y., Tsuchiya, S., Saito, R., and Yokota, J., Contribution
of the NQO1 and GSTT1 polymorphisms to lung adenocarcinoma susceptibility.
Cancer Epidemiol Biomarkers Prev, 2002. 11(8): 730-8.
140. Song, J.P., Kitayama, Y., Igarashi, H., Guo, R.J., Wang, Y.J.,
Kobayashi, T., Konno, H., Kataoka, H., Tanaka, M., and Sugimura, H.,
Centromere numerical abnormality in the papillary, papillotubular type of
early gastric cancer, a further characterization of a subset of gastric
cancer. Int J Oncol, 2002. 21(6): 1205-11.
141. Ohta, S., Nishizawa, S., Namba, H., and Sugimura, H., Bilateral
cavernous sinus actinomycosis resulting in painful ophthalmoplegia. Case
report. J Neurosurg, 2002. 96(3): 600-2.
142. Ohta, M., Konno, H., Tanaka, T., Baba, M., Kamiya, K., Mitsuoka,
H., Unno, N., Sugimura, H., and Nakamura, S., Gastrojejunocolic fistula
after gastrectomy with Billroth II reconstruction: report of a case. Surg
Today, 2002. 32(4): 367-70.
143. Nakamura, T., Maruyama, K., Kashiwabara, H., Sunayama, K., Ohata,
K., Fukazawa, A., Yasumi, K., Sugimura, H., and Nakamura, S.,
Diverticulitis causing a high serum level of carbohydrate antigen 19-9:
report of a case. Surg Today, 2002. 32(3): 282-4.
144. Matsuda, H., Chida, K., Miwa, S., Nakano, H., Kuwata, H., Suzuki,
K., Yokomura, K., Asada, K., Nakamura, Y., Inui, N., Suda, T., Nakamura,
H., Naito, Y., and Sugimura, H., [An autopsy case of cor pulmonale due to
a pulmonary tumor embolism as the first clinical manifestation of occult
gastric cancer]. Nihon Kokyuki Gakkai Zasshi, 2002. 40(11): 910-4.
145. Li, Z., Wang, Y., Song, J., Kataoka, H., Yoshii, S., Gao, C., Zhou,
J., Ota, S., Tanaka, M., and Sugimura, H., Genomic structure of the human
beta-PIX gene and its alteration in gastric cancer. Cancer Lett, 2002.
177(2): 203-8.
146. Kobayashi, T., Sugimura, H., and Kimura, T., Total gastrectomy is
not always necessary for advanced gastric cancer of the cardia. Dig Surg,
2002. 19(1): 15-21.
147. Kataoka, H., Tanaka, M., Kanamori, M., Yoshii, S., Ihara, M., Wang,
Y.J., Song, J.P., Li, Z.Y., Arai, H., Otsuki, Y., Kobayashi, T., Konno,
H., Hanai, H., and Sugimura, H., Expression profile of EFNB1, EFNB2, two
ligands of EPHB2 in human gastric cancer. J Cancer Res Clin Oncol, 2002.
128(7): 343-8.
148. Gao, C.M., Takezaki, T., Wu, J.Z., Li, Z.Y., Liu, Y.T., Li, S.P.,
Ding, J.H., Su, P., Hu, X., Xu, T.L., Sugimura, H., and Tajima, K.,
Glutathione-S-transferases M1 (GSTM1) and GSTT1 genotype, smoking,
consumption of alcohol and tea and risk of esophageal and stomach cancers:
a case-control study of a high-incidence area in Jiangsu Province, China.
Cancer Lett, 2002. 188(1-2): 95-102.
149. Gao, C., Takezaki, T., Wu, J., Li, Z., Wang, J., Ding, J., Liu, Y.,
Hu, X., Xu, T., Tajima, K., and Sugimura, H., Interaction between cytochrome
P-450 2E1 polymorphisms and environmental factors with risk of esophageal
and stomach cancers in Chinese. Cancer Epidemiol Biomarkers Prev, 2002.
11(1): 29-34.
150. Furuta, T., Shirai, N., Takashima, M., Xiao, F., and Sugimura, H.,
Effect of genotypic differences in interleukin-1 beta on gastric acid
secretion in Japanese patients infected with Helicobacter pylori. Am J Med,
2002. 112(2): 141-3.
151. Furuta, T., El-Omar, E.M., Xiao, F., Shirai, N., Takashima, M., and
Sugimura, H., Interleukin 1beta polymorphisms increase risk of
hypochlorhydria and atrophic gastritis and reduce risk of duodenal ulcer
recurrence in Japan. Gastroenterology, 2002. 123(1): 92-105.
152. Zhu, Y., Wang, D., and Sugimura, H., [Mutation analysis of tumor
suppressor gene PTEN in bone and soft tissue tumors]. Zhonghua Yi Xue Za
Zhi, 2001. 81(12): 715-8.
153. Yoshii, S., Tanaka, M., Otsuki, Y., Fujiyama, T., Kataoka, H., Arai,
H., Hanai, H., and Sugimura, H., Involvement of alpha-PAK-interacting
exchange factor in the PAK1-c-Jun NH(2)-terminal kinase 1 activation and
apoptosis induced by benzo[a]pyrene. Mol Cell Biol, 2001. 21(20):
6796-807.
154. Wang, Y.J., Oba, S.M., Yoshii, S., Song, J.P., Wang, Y., Kanamori,
M., Ota, S., Tanaka, M., and Sugimura, H., Genomic structure of human
alpha-pix, and variable deletions in a poly (T) tract in gastric cancer
tissue. Cancer Lett, 2001. 164(1): 69-75.
155. Takashima, M., Furuta, T., Hanai, H., Sugimura, H., and Kaneko, E.,
Effects of Helicobacter pylori infection on gastric acid secretion and
serum gastrin levels in Mongolian gerbils. Gut, 2001. 48(6): 765-73.
156. Otsuki, Y., Tanaka, M., Yoshii, S., Kawazoe, N., Nakaya, K., and
Sugimura, H., Tumor metastasis suppressor nm23H1 regulates Rac1 GTPase by
interaction with Tiam1. Proc Natl Acad Sci U S A, 2001. 98(8): 4385-90.
157. Oba, S.M., Wang, Y.J., Song, J.P., Li, Z.Y., Kobayashi, K., Tsugane,
S., Hamada, G.S., Tanaka, M., and Sugimura, H., Genomic structure and loss
of heterozygosity of EPHB2 in colorectal cancer. Cancer Lett, 2001. 164(1):
97-104.
158. Nakamura, T., Ozawa, T., Kawasaki, T., Nakamura, H., and Sugimura,
H., Glucose-6-phosphatase gene mutations in 20 adult Japanese patients with
glycogen storage disease type 1a with reference to hepatic tumors. J
Gastroenterol Hepatol, 2001. 16(12): 1402-8.
159. Hanaoka, T., Sugimura, H., Nagura, K., Ihara, M., Li, X.J., Hamada,
G.S., Nishimoto, I., Kowalski, L.P., Yokota, J., and Tsugane, S., hOGG1
exon7 polymorphism and gastric cancer in case-control studies of Japanese
Brazilians and non-Japanese Brazilians. Cancer Lett, 2001. 170(1): 53-61.
160. Guo, R.J., Arai, H., Kitayama, Y., Igarashi, H., Hemmi, H., Arai,
T., Hanai, H., and Sugimura, H., Microsatellite instability of papillary
subtype of human gastric adenocarcinoma and hMLH1 promoter
hypermethylation in the surrounding mucosa. Pathol Int, 2001. 51(4):
240-7.
161. Garte, S., Gaspari, L., Alexandrie, A.K., Ambrosone, C., Autrup,
H., Autrup, J.L., Baranova, H., Bathum, L., Benhamou, S., Boffetta, P.,
Bouchardy, C., Breskvar, K., Brockmoller, J., Cascorbi, I., Clapper, M.L.,
Coutelle, C., Daly, A., Dell'Omo, M., Dolzan, V., Dresler, C.M., Fryer,
A., Haugen, A., Hein, D.W., Hildesheim, A., Hirvonen, A., Hsieh, L.L.,
Ingelman-Sundberg, M., Kalina, I., Kang, D., Kihara, M., Kiyohara, C.,
Kremers, P., Lazarus, P., Le Marchand, L., Lechner, M.C., van Lieshout,
E.M., London, S., Manni, J.J., Maugard, C.M., Morita, S., Nazar-Stewart,
V., Noda, K., Oda, Y., Parl, F.F., Pastorelli, R., Persson, I., Peters,
W.H., Rannug, A., Rebbeck, T., Risch, A., Roelandt, L., Romkes, M., Ryberg,
D., Salagovic, J., Schoket, B., Seidegard, J., Shields, P.G., Sim, E.,
Sinnet, D., Strange, R.C., Stucker, I., Sugimura, H., To-Figueras, J.,
Vineis, P., Yu, M.C., and Taioli, E., Metabolic gene polymorphism
frequencies in control populations. Cancer Epidemiol Biomarkers Prev, 2001.
10(12): 1239-48.
162. Furuta, T., Shirai, N., Takashima, M., Xiao, F., Hanai, H., Sugimura,
H., Ohashi, K., Ishizaki, T., and Kaneko, E., Effect of genotypic
differences in CYP2C19 on cure rates for Helicobacter pylori infection by
triple therapy with a proton pump inhibitor, amoxicillin, and
clarithromycin. Clin Pharmacol Ther, 2001. 69(3): 158-68.
163. Furuta, T., Shirai, N., Takashima, M., Xiao, F., Hanai, H., Nakagawa,
K., Sugimura, H., Ohashi, K., and Ishizaki, T., Effects of genotypic
differences in CYP2C19 status on cure rates for Helicobacter pylori
infection by dual therapy with rabeprazole plus amoxicillin.
Pharmacogenetics, 2001. 11(4): 341-8.
164. Endoh, A., Inoue, N., Katoh, T., Nakamura, T., Sugimura, H., and
Ohzeki, T., A case of glycogen storage disease IA with multiple hepatic
tumors managed by transcatheter arterial embolization and an acarbose diet.
J Pediatr Gastroenterol Nutr, 2001. 33(3): 333-6.
165. Baba, M., Konno, H., Tanaka, T., Kamiya, K., Baba, S., Sugimura,
H., and Nakamura, S., Relationship of p53 and Helicobacter pylori to
clinicopathological features of human remnant stomach cancer after gastric
surgery for primary gastric cancer. Oncol Rep, 2001. 8(4): 831-4.
166. Wang, D.Y., Xiang, Y.Y., Li, X.J., Hashimoto, M., Tanaka, M., and
Sugimura, H., Mxi1 is a potential cellular target of carcinogens and
frequently mutated in experimental rat tumors and tumor cell lines. Pathol
Int, 2000. 50(5): 373-83.
167. Tanida, S., Tanioka, F., Inukai, M., Yoshioka, N., Saida, Y., Imai,
K., Nakamura, T., Kitamura, H., and Sugimura, H., Ewing's
sarcoma/peripheral primitive neuroectodermal tumor (pPNET) arising in the
omentum as a multilocular cyst with intracystic hemorrhage. J Gastroenterol,
2000. 35(12): 933-40.
168. Shinmura, K., Kohno, T., Takeuchi-Sasaki, M., Maeda, M., Segawa,
T., Kamo, T., Sugimura, H., and Yokota, J., Expression of the OGG1-type
1a (nuclear form) protein in cancerous and non-cancerous human cells. Int
J Oncol, 2000. 16(4): 701-7.
169. Saigusa, N., Kurahashi, T., Nakamura, T., Sugimura, H., Baba, S.,
Konno, H., and Nakamura, S., Functional outcome of stapled ileal pouch-anal
canal anastomosis versus handsewn pouch-anal anastomosis. Surg Today, 2000.
30(7): 575-81.
170. Ohta, M., Konno, H., Kamiya, K., Suwa, D., Baba, M., Tanaka, T.,
Nakamura, T., Nishino, N., Sugimura, H., and Nakamura, S., Crohn's disease
of the esophagus: report of a case. Surg Today, 2000. 30(3): 262-7.
171. Nishimura, T., Nozue, M., Suzuki, K., Imai, M., Suzuki, S., Sakahara,
H., Nakamura, T., and Sugimura, H., Perianal mucinous carcinoma
successfully treated with a combination of external beam radiotherapy and
high dose rate interstitial brachytherapy. Br J Radiol, 2000. 73(870):
661-4.
172. Nishimoto, I.N., Hanaoka, T., Sugimura, H., Nagura, K., Ihara, M.,
Li, X.J., Arai, T., Hamada, G.S., Kowalski, L.P., and Tsugane, S.,
Cytochrome P450 2E1 polymorphism in gastric cancer in Brazil: case-control
studies of Japanese Brazilians and non-Japanese Brazilians. Cancer
Epidemiol Biomarkers Prev, 2000. 9(7): 675-80.
173. Matsushita, I., Hanai, H., Sato, Y., Arai, H., Iida, T., Hosoda,
Y., Kaneko, E., Yasumi, K., and Sugimura, H., Protein-losing enteropathy
caused by mesenteric venous thrombosis with protein C deficiency. J Clin
Gastroenterol, 2000. 30(1): 94-7.
174. Koda, K., Yoshino, G., Honda, S., Watanabe, F., and Sugimura, H.,
Adenocarcinoma of the rectum with various grades of atypia in association
with Crohn's disease: a case report and immunohistochemistry of p53 and
Ki-67. Pathol Int, 2000. 50(4): 318-26.
175. Kobayashi, K., Kitayama, Y., Igarashi, H., Yoshino, G., Kobayashi,
T., Kazui, T., and Sugimura, H., Intratumor heterogeneity of centromere
numerical abnormality in multiple primary gastric cancers: application of
fluorescence in situ hybridization with intermittent microwave irradiation
on paraffin-embedded tissue. Jpn J Cancer Res, 2000. 91(11): 1134-41.
176. Kitayama, Y., Igarashi, H., and Sugimura, H., Initial intermittent
microwave irradiation for fluorescence in situ hybridization analysis in
paraffin-embedded tissue sections of gastrointestinal neoplasia. Lab
Invest, 2000. 80(5): 779-81.
177. Kitayama, Y., Igarashi, H., and Sugimura, H., Different
vulnerability among chromosomes to numerical instability in gastric
carcinogenesis: stage-dependent analysis by FISH with the use of microwave
irradiation. Clin Cancer Res, 2000. 6(8): 3139-46.
178. Kitayama, Y., Honda, S., and Sugimura, H., Epstein-Barr
virus-related gastric pseudolymphoma in infectious mononucleosis.
Gastrointest Endosc, 2000. 52(2): 290-1.
179. Igarashi, H., Nagura, K., and Sugimura, H., Trypan blue as a slow
migrating dye for SSCP detection in polyacrylamide gel electrophoresis.
Biotechniques, 2000. 29(1): 42-4.
180. Hashimoto, M., Wang, D.Y., Kamo, T., Zhu, Y., Tsujiuchi, T., Konishi,
Y., Tanaka, M., and Sugimura, H., Isolation and localization of type IIb
Na/Pi cotransporter in the developing rat lung. Am J Pathol, 2000. 157(1):
21-7.
181. Dragani, T.A., Hirohashi, S., Juji, T., Kawajiri, K., Kihara, M.,
Ono-Kihara, M., Manenti, G., Nomoto, T., Sugimura, H., Genka, K., Yokota,
J., Takahashi, T., Mitsudomi, T., and Nagao, M., Population-based mapping
of pulmonary adenoma susceptibility 1 locus. Cancer Res, 2000. 60(18):
5017-20.
182. Ando, H., Nishimura, T., Nakamura, T., Sugimura, H., and Nakamura,
S., Chemoradiation therapy for squamous cell carcinoma of anal canal
cancer: report of a case. Radiat Med, 2000. 18(3): 199-203.
183. Yuan, X., Ishibashi, S., Hatakeyama, S., Saito, M., Nakayama, J.,
Nikaido, R., Haruyama, T., Watanabe, Y., Iwata, H., Iida, M., Sugimura,
H., Yamada, N., and Ishikawa, F., Presence of telomeric G-strand tails in
the telomerase catalytic subunit TERT knockout mice. Genes Cells, 1999.
4(10): 563-72.
184. Yoshii, S., Tanaka, M., Otsuki, Y., Wang, D.Y., Guo, R.J., Zhu, Y.,
Takeda, R., Hanai, H., Kaneko, E., and Sugimura, H., alphaPIX nucleotide
exchange factor is activated by interaction with phosphatidylinositol
3-kinase. Oncogene, 1999. 18(41): 5680-90.
185. Ueda, M., Wang, Y., Sugimura, H., Tamura, S., Kondoh, M., and
Ichihashi, M., A case of multiple sebaceous epithelioma: analysis of
microsatellite instability. J Dermatol, 1999. 26(3): 178-82.
186. Suzuki, K., Kazui, T., Yoshida, M., Uno, T., Kobayashi, T., Kimura,
T., Yoshida, T., and Sugimura, H., Drug-induced apoptosis and p53, BCL-2
and BAX expression in breast cancer tissues in vivo and in fibroblast cells
in vitro. Jpn J Clin Oncol, 1999. 29(7): 323-31.
187. Sugimura, H., Kohno, T., Wakai, K., Nagura, K., Genka, K., Igarashi,
H., Morris, B.J., Baba, S., Ohno, Y., Gao, C., Li, Z., Wang, J., Takezaki,
T., Tajima, K., Varga, T., Sawaguchi, T., Lum, J.K., Martinson, J.J.,
Tsugane, S., Iwamasa, T., Shinmura, K., and Yokota, J., hOGG1 Ser326Cys
polymorphism and lung cancer susceptibility. Cancer Epidemiol Biomarkers
Prev, 1999. 8(8): 669-74.
188. Shinmura, K., Kohno, T., Takahashi, M., Sasaki, A., Ochiai, A.,
Guilford, P., Hunter, A., Reeve, A.E., Sugimura, H., Yamaguchi, N., and
Yokota, J., Familial gastric cancer: clinicopathological characteristics,
RER phenotype and germline p53 and E-cadherin mutations. Carcinogenesis,
1999. 20(6): 1127-31.
189. Nakamura, T., Ozawa, T., Kawasaki, T., Yasumi, K., Wang, D.Y.,
Kitagawa, M., Takehira, Y., Tamakoshi, K., Yamada, M., Kida, H., Sugie,
H., Nakamura, H., and Sugimura, H., Case report: Hepatocellular carcinoma
in type 1a glycogen storage disease with identification of a
glucose-6-phosphatase gene mutation in one family. J Gastroenterol Hepatol,
1999. 14(6): 553-8.
190. Li, X.J., Wang, D.Y., Zhu, Y., Guo, R.J., Wang, X.D., Lubomir, K.,
Mukai, K., Sasaki, H., Yoshida, H., Oka, T., Machinami, R., Shinmura, K.,
Tanaka, M., and Sugimura, H., Mxi1 mutations in human neurofibrosarcomas.
Jpn J Cancer Res, 1999. 90(7): 740-6.
191. Kobayashi, T., Suzuki, K., Arai, T., and Sugimura, H.,
Angiomyofibroblastoma arising from the fallopian tube. Obstet Gynecol,
1999. 94(5 Pt 2): 833-4.
192. Kitayama, Y., Igarashi, H., and Sugimura, H., Amplification of FISH
signals using intermittent microwave irradiation for analysis of
chromosomal instability in gastric cancer. Mol Pathol, 1999. 52(6):
357-9.
193. Isogaki, J., Shinmura, K., Yin, W., Arai, T., Koda, K., Kimura, T.,
Kino, I., and Sugimura, H., Microsatellite instability and K-ras mutations
in gastric adenomas, with reference to associated gastric cancers. Cancer
Detect Prev, 1999. 23(3): 204-14.
194. Hosoda, Y., Hanai, H., Arai, H., Sato, Y., Kajimura, M., Sugimura,
H., and Kaneko, E., Early gastric cancer exhibiting the features of
submucosal tumor: report of a case. Endoscopy, 1999. 31(2): S11.
195. Arai, H., Hanai, H., Furuta, T., Sato, Y., Yamada, M., Kaneko, E.,
Baba, S., and Sugimura, H., A patient who survived total colonic type
ulcerative colitis complicated by toxic megacolon, disseminated
intravascular coagulation, methicillin-resistant Staphylococcus aureus
infection and bilateral femoral phlebothrombosis. J Gastroenterol, 1999.
34(3): 395-9.
196. Yasumi, K., Guo, R.J., Hanai, H., Arai, H., Kaneko, E., Konno, H.,
Takenoshita, S., Hagiwara, K., and Sugimura, H., Transforming growth factor
beta type II receptor (TGF beta RII) mutation in gastric lymphoma without
mutator phenotype. Pathol Int, 1998. 48(2): 134-7.
197. Wang, Y., Shinmura, K., Guo, R.J., Isogaki, J., Wang, D.Y., Kino,
I., and Sugimura, H., Mutational analyses of multiple target genes in
histologically heterogeneous gastric cancer with microsatellite
instability. Jpn J Cancer Res, 1998. 89(12): 1284-91.
198. Uchida, H., Ando, H., Maruyama, K., Kobayashi, H., Toda, H., Ogawa,
H., Ozawa, T., Matsuda, Y., Sugimura, H., Kanno, T., and Baba, S., Genetic
alterations of mixed hyperplastic adenomatous polyps in the colon and
rectum. Jpn J Cancer Res, 1998. 89(3): 299-306.
199. Tanaka, M., Wang, D.Y., Kamo, T., Igarashi, H., Wang, Y., Xiang,
Y.Y., Tanioka, F., Naito, Y., and Sugimura, H., Interaction of
EphB2-tyrosine kinase receptor and its ligand conveys dorsalization signal
in Xenopus laevis development. Oncogene, 1998. 17(12): 1509-16.
200. Takashima, M., Hanai, H., Sato, Y., Arai, H., Furuta, T., Shirakawa,
K., Chida, K., Sato, A., Sugimura, H., Baba, S., and Kaneko, E., Association
of Crohn's ileitis with pulmonary and cutaneous sarcoidosis in a Japanese
patient. Gastrointest Endosc, 1998. 48(6): 637-9.
201. Sugimura, H., Wakai, K., Genka, K., Nagura, K., Igarashi, H.,
Nagayama, K., Ohkawa, A., Baba, S., Morris, B.J., Tsugane, S., Ohno, Y.,
Gao, C., Li, Z., Takezaki, T., Tajima, K., and Iwamasa, T., Association
of Ile462Val (Exon 7) polymorphism of cytochrome P450 IA1 with lung cancer
in the Asian population: further evidence from a case-control study in
Okinawa. Cancer Epidemiol Biomarkers Prev, 1998. 7(5): 413-7.
202. Shinmura, K., Tani, M., Isogaki, J., Wang, Y., Sugimura, H., and
Yokota, J., RER phenotype and its associated mutations in familial gastric
cancer. Carcinogenesis, 1998. 19(2): 247-51.
203. Shinmura, K., Kohno, T., Kasai, H., Koda, K., Sugimura, H., and
Yokota, J., Infrequent mutations of the hOGG1 gene, that is involved in
the excision of 8-hydroxyguanine in damaged DNA, in human gastric cancer.
Jpn J Cancer Res, 1998. 89(8): 825-8.
204. Naito, Y., Ohori, K., Tanaka, M., Kamo, T., Baba, S., Hori, T.,
Hashizume, K., and Sugimura, H., Collagen and elastin synthesis by desmoid
tumor in vitro. Pathol Int, 1998. 48(8): 603-10.
205. Konno, H., Arai, T., Tanaka, T., Baba, M., Matsumoto, K., Kanai,
T., Nakamura, S., Baba, S., Naito, Y., Sugimura, H., Yukita, A., Asano,
M., and Suzuki, H., Antitumor effect of a neutralizing antibody to vascular
endothelial growth factor on liver metastasis of endocrine neoplasm. Jpn
J Cancer Res, 1998. 89(9): 933-9.
206. Kohno, T., Shinmura, K., Tosaka, M., Tani, M., Kim, S.R., Sugimura,
H., Nohmi, T., Kasai, H., and Yokota, J., Genetic polymorphisms and
alternative splicing of the hOGG1 gene, that is involved in the repair of
8-hydroxyguanine in damaged DNA. Oncogene, 1998. 16(25): 3219-25.
207. Kobayashi, T., Kimura, T., Takabayashi, N., and Sugimura, H., Two
synchronous solid and cystic tumors of the pancreas. J Gastroenterol, 1998.
33(3): 439-42.
208. Kiyokawa, E., Hashimoto, Y., Kurata, T., Sugimura, H., and Matsuda,
M., Evidence that DOCK180 up-regulates signals from the CrkII-p130(Cas)
complex. J Biol Chem, 1998. 273(38): 24479-84.
209. Kiyokawa, E., Hashimoto, Y., Kobayashi, S., Sugimura, H., Kurata,
T., and Matsuda, M., Activation of Rac1 by a Crk SH3-binding protein,
DOCK180. Genes Dev, 1998. 12(21): 3331-6.
210. Kitayama, Y., Sugimura, H., and Nakamura, S.I., Gastric
plasmacytoma coexistent with plasma cell granuloma in a patient with
gastric cancer. J Gastroenterol, 1998. 33(1): 80-5.
211. Guo, R.J., Wang, Y., Kaneko, E., Wang, D.Y., Arai, H., Hanai, H.,
Takenoshita, S., Hagiwara, K., Harris, C.C., and Sugimura, H., Analyses
of mutation and loss of heterozygosity of coding sequences of the entire
transforming growth factor beta type II receptor gene in sporadic human
gastric cancer. Carcinogenesis, 1998. 19(9): 1539-44.
212. Yin, J., Kong, D., Wang, S., Zou, T.T., Souza, R.F., Smolinski, K.N.,
Lynch, P.M., Hamilton, S.R., Sugimura, H., Powell, S.M., Young, J., Abraham,
J.M., and Meltzer, S.J., Mutation of hMSH3 and hMSH6 mismatch repair genes
in genetically unstable human colorectal and gastric carcinomas. Hum Mutat,
1997. 10(6): 474-8.
213. Xiang, Y.Y., Wang, D.Y., Tanaka, M., Suzuki, M., Kiyokawa, E.,
Igarashi, H., Naito, Y., Shen, Q., and Sugimura, H., Expression of
high-mobility group-1 mRNA in human gastrointestinal adenocarcinoma and
corresponding non-cancerous mucosa. Int J Cancer, 1997. 74(1): 1-6.
214. Wang, Y., Shinmura, K., and Sugimura, H., [Microsatellite
instability in gastric cancer with varied structure]. Rinsho Byori, 1997.
45(7): 651-5.
215. Wang, S., Souza, R.F., Kong, D., Yin, J., Smolinski, K.N., Zou, T.T.,
Frank, T., Young, J., Flanders, K.C., Sugimura, H., Abraham, J.M., and
Meltzer, S.J., Deficient transforming growth factor-beta1 activation and
excessive insulin-like growth factor II (IGFII) expression in IGFII
receptor-mutant tumors. Cancer Res, 1997. 57(13): 2543-6.
216. Souza, R.F., Yin, J., Smolinski, K.N., Zou, T.T., Wang, S., Shi,
Y.Q., Rhyu, M.G., Cottrell, J., Abraham, J.M., Biden, K., Simms, L., Leggett,
B., Bova, G.S., Frank, T., Powell, S.M., Sugimura, H., Young, J., Harpaz,
N., Shimizu, K., Matsubara, N., and Meltzer, S.J., Frequent mutation of
the E2F-4 cell cycle gene in primary human gastrointestinal tumors. Cancer
Res, 1997. 57(12): 2350-3.
217. Simms, L.A., Zou, T.T., Young, J., Shi, Y.Q., Lei, J., Appel, R.,
Rhyu, M.G., Sugimura, H., Chenevix-Trench, G., Souza, R.F., Meltzer, S.J.,
and Leggett, B.A., Apparent protection from instability of repeat sequences
in cancer-related genes in replication error positive gastrointestinal
cancers. Oncogene, 1997. 14(21): 2613-8.
218. Shinmura, K., Yin, W., Isogaki, J., Saitoh, K., Kanazawa, K., Koda,
K., Yokota, J., Kino, I., Arai, T., and Sugimura, H., Stage-dependent
evaluation of microsatellite instability in gastric carcinoma with
familial clustering. Cancer Epidemiol Biomarkers Prev, 1997. 6(9): 693-7.
219. Shinmura, K., Kasai, H., Sasaki, A., Sugimura, H., and Yokota, J.,
8-hydroxyguanine (7,8-dihydro-8-oxoguanine) DNA glycosylase and AP lyase
activities of hOGG1 protein and their substrate specificity. Mutat Res,
1997. 385(1): 75-82.
220. Kasami, M., Yoshida, M., Isogaki, J., Ogawa, H., Shinmura, K., Endo,
Y., Kiyokawa, E., Naito, Y., Arai, T., Kimura, T., Inoue, R., and Sugimura,
H., Bilateral breast tumors, malignant phyllodes tumor and invasive lobular
carcinoma in a 46,XX/46,XY mosaic female with family history of breast
cancer. Pathol Int, 1997. 47(2-3): 147-54.
221. Kanai, T., Konno, H., Maruyama, K., Baba, M., Tanaka, T., Maruo,
Y., Nishino, N., Nakamura, S., Baba, S., and Sugimura, H., p53
overexpression and proliferative activity do not correlate with lymph node
metastasis in early gastric cancer. Eur Surg Res, 1997. 29(1): 35-41.
222. Inoue, R., Ushijima, T., Fukutomi, T., Fukami, A., Sugimura, H.,
Inoue, S., Okonogi, H., Sugimura, T., Matsumoto, Y., and Nagao, M., BRCA2
germline mutations in Japanese breast cancer families. Int J Cancer, 1997.
74(2): 199-204.
223. Arai, T., Maruyama, K., Kamo, T., and Sugimura, H., Origin of
intraepithelial apoptotic cells in human colorectal adenomas. Pathol Int,
1997. 47(5): 333-5.
224. Yokota, N., Aruga, J., Takai, S., Yamada, K., Hamazaki, M., Iwase,
T., Sugimura, H., and Mikoshiba, K., Predominant expression of human zic
in cerebellar granule cell lineage and medulloblastoma. Cancer Res, 1996.
56(2): 377-83.
225. Xiang, Y.Y., Wang, D.Y., Tanaka, M., Igarashi, H., Naito, Y.,
Ohtawara, Y., Shen, Q., and Sugimura, H., Expression of structure-specific
recognition protein mRNA in fetal kidney and Fe-nitrilotriacetate-induced
renal carcinoma in the rat. Cancer Lett, 1996. 106(2): 271-8.
226. Wang, D.Y., Xiang, Y.Y., Tanaka, M., Shen, Q., and Sugimura, H.,
Identification of cytokeratin subspecies altered in rat experimental
esophageal tumors by subtractive cloning. Cancer Lett, 1996. 108(1):
119-27.
227. Souza, R.F., Appel, R., Yin, J., Wang, S., Smolinski, K.N., Abraham,
J.M., Zou, T.T., Shi, Y.Q., Lei, J., Cottrell, J., Cymes, K., Biden, K.,
Simms, L., Leggett, B., Lynch, P.M., Frazier, M., Powell, S.M., Harpaz,
N., Sugimura, H., Young, J., and Meltzer, S.J., Microsatellite instability
in the insulin-like growth factor II receptor gene in gastrointestinal
tumours. Nat Genet, 1996. 14(3): 255-7.
228. Saigusa, N., Maruyama, K., Sugimura, H., Endoh, Y., and Baba, S.,
[The results of p53 immunostaining in colorectal adenomas, early cancers,
advanced cancers and their hepatic metastasis]. Gan To Kagaku Ryoho, 1996.
23 Suppl 2: 159-63.
229. Masui, T., Takahashi, M., Sugimura, H., Isoda, H., Mochizuki, T.,
Kaneko, M., and Nishizawa, S., Pituitary prolactinoma mimicking tumor
originating from the sphenoid sinus or clivus. Radiat Med, 1996. 14(4):
189-91.
230. Masui, T., Kurosawa, Y., Iwase, T., Sugimura, H., Isoda, H.,
Takahashi, M., Mochizuki, T., and Takinami, M., Meningeal
hemangiopericytoma metastatic to the heart. Radiat Med, 1996. 14(2):
91-4.
231. Maruyama, K., Tanaka, T., Baba, S., Nakamura, S., Endo, Y., and
Sugimura, H., p53 accumulation in colorectal cancer with hepatic metastasis.
Jpn J Cancer Res, 1996. 87(4): 368-76.
232. Iwase, T., Nishimura, M., Sugimura, H., Igarashi, H., Ozawa, F.,
Shinmura, K., Suzuki, M., Tanaka, M., and Kino, I., Localization of Menkes
gene expression in the mouse brain; its association with neurological
manifestations in Menkes model mice. Acta Neuropathol, 1996. 91(5):
482-8.
233. Xiang, Y.Y., Wang, D.Y., Tanaka, M., Igarashi, H., Kamo, T., Shen,
Q., Sugimura, H., and Kino, I., Efficient and specific induction of
esophageal tumors in rats by precursors of N-nitrososarcosine ethyl ester.
Pathol Int, 1995. 45(6): 415-21.
234. Sugimura, H., Yamamoto, H., Watabiki, H., Ogawa, H., Harada, H.,
Saitoh, I., Miyamura, T., Inoue, M., Tajima, K., and Kino, I., Correlation
of detectability of hepatitis C virus genome in saliva of elderly Japanese
symptomatic HCV carriers with their hepatic function. Infection, 1995.
23(5): 258-62.
235. Sugimura, H., Hamada, G.S., Suzuki, I., Iwase, T., Kiyokawa, E.,
Kino, I., and Tsugane, S., CYP1A1 and CYP2E1 polymorphism and lung cancer,
case-control study in Rio de Janeiro, Brazil. Pharmacogenetics, 1995. 5
Spec No: S145-8.
236. Shinmura, K., Sugimura, H., Naito, Y., Shields, P.G., and Kino, I.,
Frequent co-occurrence of mutator phenotype in synchronous, independent
multiple cancers of the stomach. Carcinogenesis, 1995. 16(12): 2989-93.
237. Oda, H., Nakatsuru, Y., Imai, Y., Sugimura, H., and Ishikawa, T.,
A mutational hot spot in the p53 gene is associated with hepatoblastomas.
Int J Cancer, 1995. 60(6): 786-90.
238. Kitayama, Y., Sugimura, H., Tanaka, M., Nakamura, S., and Kino, I.,
Expression of p53 and flow cytometric DNA analysis of isolated neoplastic
glands of the stomach: an application of the gland isolation method.
Virchows Arch, 1995. 426(6): 557-62.
239. Kitayama, Y., Sugimura, H., Arai, T., Nagamatsu, K., and Kino, I.,
Primary osteosarcoma arising from cirrhotic liver. Pathol Int, 1995. 45(4):
320-5.
240. Kitayama, Y., Nakamura, S., Sugimura, H., and Kino, I.,
Cytophotometric and flow cytometric DNA content of isolated glands in
gastric neoplasia. Gut, 1995. 36(4): 516-21.
241. Iwase, T., Nishizawa, S., Baba, S., Hinokuma, K., Sugimura, H.,
Nakamura, S., Uemura, K., Shirasawa, H., and Kino, I., Intrasellar neuronal
choristoma associated with growth hormone-producing pituitary adenoma
containing amyloid deposits. Hum Pathol, 1995. 26(8): 925-8.
242. Hamada, G.S., Sugimura, H., Suzuki, I., Nagura, K., Kiyokawa, E.,
Iwase, T., Tanaka, M., Takahashi, T., Watanabe, S., Kino, I., and et al.,
The heme-binding region polymorphism of cytochrome P450IA1 (CypIA1),
rather than the RsaI polymorphism of IIE1 (CypIIE1), is associated with
lung cancer in Rio de Janeiro. Cancer Epidemiol Biomarkers Prev, 1995. 4(1):
63-7.
243. Endo, Y., Sugimura, H., and Kino, I., Monoclonality of normal human
colonic crypts. Pathol Int, 1995. 45(8): 602-4.
244. Baba, S., Masago, S.A., Takahashi, T., Kasama, T., Sugimura, H.,
Tsugane, S., Tsutsui, Y., and Shirasawa, H., A novel allelic variant of
serum amyloid A, SAA1 gamma: genomic evidence, evolution, frequency, and
implication as a risk factor for reactive systemic AA-amyloidosis. Hum Mol
Genet, 1995. 4(6): 1083-7.
245. Xiang, Y.Y., Tanaka, M., Suzuki, M., Igarashi, H., Kiyokawa, E.,
Naito, Y., Ohtawara, Y., Shen, Q., Sugimura, H., and Kino, I., Isolation
of complementary DNA encoding K-cadherin, a novel rat cadherin
preferentially expressed in fetal kidney and kidney carcinoma. Cancer Res,
1994. 54(11): 3034-41.
246. Wang, D.Y., Xiang, Y.Y., Tanaka, M., Li, X.R., Li, J.L., Shen, Q.,
Sugimura, H., and Kino, I., High prevalence of p53 protein overexpression
in patients with esophageal cancer in Linxian, China and its relationship
to progression and prognosis. Cancer, 1994. 74(12): 3089-96.
247. Takai, S., Tanaka, M., Sugimura, H., Yamada, K., Naito, Y., Kino,
I., and Matsuda, M., Mapping of the human C3G gene coding a guanine
nucleotide releasing protein for Ras family to 9q34.3 by fluorescence in
situ hybridization. Hum Genet, 1994. 94(5): 549-50.
248. Sugimura, H., Suzuki, I., Hamada, G.S., Iwase, T., Takahashi, T.,
Nagura, K., Iwata, H., Watanabe, S., Kino, I., and Tsugane, S., Cytochrome
P-450 lA1 genotype in lung cancer patients and controls in Rio de Janeiro,
Brazil. Cancer Epidemiol Biomarkers Prev, 1994. 3(2): 145-8.
249. Kiyokawa, E., Takai, S., Tanaka, M., Iwase, T., Suzuki, M., Xiang,
Y.Y., Naito, Y., Yamada, K., Sugimura, H., and Kino, I., Overexpression
of ERK, an EPH family receptor protein tyrosine kinase, in various human
tumors. Cancer Res, 1994. 54(14): 3645-50.
250. Kato, S., Shields, P.G., Caporaso, N.E., Sugimura, H., Trivers,
G.E., Tucker, M.A., Trump, B.F., Weston, A., and Harris, C.C., Analysis
of cytochrome P450 2E1 genetic polymorphisms in relation to human lung
cancer. Cancer Epidemiol Biomarkers Prev, 1994. 3(6): 515-8.
251. Igarashi, H., Sugimura, H., Maruyama, K., Kitayama, Y., Ohta, I.,
Suzuki, M., Tanaka, M., Dobashi, Y., and Kino, I., Alteration of
immunoreactivity by hydrated autoclaving, microwave treatment, and simple
heating of paraffin-embedded tissue sections. APMIS, 1994. 102(4):
295-307.
252. Dobashi, Y., Sugimura, H., Sakamoto, A., Mernyei, M., Mori, M.,
Oyama, T., and Machinami, R., Stepwise participation of p53 gene mutation
during dedifferentiation of human thyroid carcinomas. Diagn Mol Pathol,
1994. 3(1): 9-14.
253. Arai, T., Sugimura, H., Suzuki, M., Iwase, T., Sakuramachi, S.,
Kimura, T., Harada, Y., and Kino, I., Benign schwannoma of the esophagus:
report of two cases with immunohistochemical and ultrastructural studies.
Pathol Int, 1994. 44(6): 460-5.
254. Suzuki, M., Tanaka, M., Iwase, T., Naito, Y., Sugimura, H., and Kino,
I., Over-expression of HOX-8, the human homologue of the mouse Hox-8
homeobox gene, in human tumors. Biochem Biophys Res Commun, 1993. 194(1):
187-93.
255. Shiseki, M., Nishikawa, R., Yamamoto, H., Ochiai, A., Sugimura, H.,
Shitara, N., Sameshima, Y., Mizoguchi, H., Sugimura, T., and Yokota, J.,
Germ-line p53 mutation is uncommon in patients with triple primary cancers.
Cancer Lett, 1993. 73(1): 51-7.
256. Shields, P.G., Caporaso, N.E., Falk, R.T., Sugimura, H., Trivers,
G.E., Trump, B.F., Hoover, R.N., Weston, A., and Harris, C.C., Lung cancer,
race, and a CYP1A1 genetic polymorphism. Cancer Epidemiol Biomarkers Prev,
1993. 2(5): 481-5.
257. Iwase, T., Tanaka, M., Suzuki, M., Naito, Y., Sugimura, H., and Kino,
I., Identification of protein-tyrosine kinase genes preferentially
expressed in embryo stomach and gastric cancer. Biochem Biophys Res Commun,
1993. 194(2): 698-705.
258. Dobashi, Y., Sugimura, H., Sato, A., Hirabayashi, T., Kanda, H.,
Kitagawa, T., Kawaguchi, N., Imamura, T., and Machinami, R., Possible
association of p53 overexpression and mutation with high-grade
chondrosarcoma. Diagn Mol Pathol, 1993. 2(4): 257-63.
259. Dobashi, Y., Sakamoto, A., Sugimura, H., Mernyei, M., Mori, M.,
Oyama, T., and Machinami, R., Overexpression of p53 as a possible prognostic
factor in human thyroid carcinoma. Am J Surg Pathol, 1993. 17(4): 375-81.
260. Weston, A., Caporaso, N.E., Perrin, L.S., Sugimura, H., Tamai, S.,
Krontiris, T.G., Trump, B.F., Hoover, R.N., and Harris, C.C., Relationship
of H-ras-1, L-myc, and p53 polymorphisms with lung cancer risk and prognosis.
Environ Health Perspect, 1992. 98: 61-7.
261. Shields, P.G., Sugimura, H., Caporaso, N.E., Petruzzelli, S.F.,
Bowman, E.D., Trump, B.F., Weston, A., and Harris, C.C., Polycyclic
aromatic hydrocarbon-DNA adducts and the CYP1A1 restriction fragment
length polymorphism. Environ Health Perspect, 1992. 98: 191-4.
262. Kato, S., Shields, P.G., Caporaso, N.E., Hoover, R.N., Trump, B.F.,
Sugimura, H., Weston, A., and Harris, C.C., Cytochrome P450IIE1 genetic
polymorphisms, racial variation, and lung cancer risk. Cancer Res, 1992.
52(23): 6712-5.
263. Caporaso, N.E., Shields, P.G., Landi, M.T., Shaw, G.L., Tucker,
M.A., Hoover, R., Sugimura, H., Weston, A., and Harris, C.C., The
debrisoquine metabolic phenotype and DNA-based assays: implications of
misclassification for the association of lung cancer and the debrisoquine
metabolic phenotype. Environ Health Perspect, 1992. 98: 101-5.
264. Weston, A., Vineis, P., Caporaso, N.E., Krontiris, T.G., Lonergan,
J.A., and Sugimura, H., Racial variation in the distribution of Ha-ras-1
alleles. Mol Carcinog, 1991. 4(4): 265-8.
265. Sugimura, H., Weston, A., Caporaso, N.E., Shields, P.G., Bowman,
E.D., Metcalf, R.A., and Harris, C.C., Biochemical and molecular
epidemiology of cancer. Biomed Environ Sci, 1991. 4(1-2): 73-92.
266. Sugimura, H., Fukazawa, T., Saitoh, M., Nakamura, K., Shimada, H.,
and Ohtsubo, K., The histopathology of the liver in older patients with
hepatitis B virus surface antigenaemia. Virchows Arch A Pathol Anat
Histopathol, 1991. 419(5): 409-15.
267. Tamai, S., Sugimura, H., Caporaso, N.E., Resau, J.H., Trump, B.F.,
Weston, A., and Harris, C.C., Restriction fragment length polymorphism
analysis of the L-myc gene locus in a case-control study of lung cancer.
Int J Cancer, 1990. 46(3): 411-5.
268. Sugimura, H., Tsugane, S., Watanabe, S., Nanri, S., and Ishii, H.,
Hepatitis B virus markers in Japanese immigrants and their descendants in
Bolivia and native Bolivians. Gastroenterol Jpn, 1990. 25(3): 335-8.
269. Sugimura, H., Caporaso, N.E., Shaw, G.L., Modali, R.V., Gonzalez,
F.J., Hoover, R.N., Resau, J.H., Trump, B.F., Weston, A., and Harris, C.C.,
Human debrisoquine hydroxylase gene polymorphisms in cancer patients and
controls. Carcinogenesis, 1990. 11(9): 1527-30.
270. Sugimura, H., Caporaso, N.E., Modali, R.V., Hoover, R.N., Resau,
J.H., Trump, B.F., Longergan, J.A., Krontiris, T.G., Mann, D.L., Weston,
A., and et al., Association of rare alleles of the Harvey ras protooncogene
locus with lung cancer. Cancer Res, 1990. 50(6): 1857-62.
271. Harris, C.C., Weston, A., Sugimura, H., Iman, D., Shows, T.,
Stanbridge, E., Kaighn, E., and McMenamin, M., Tumor suppression studies
of human lung cancer. Prog Clin Biol Res, 1990. 340D: 21-31.
272. Harris, C.C., Reddel, R., Modali, R., Lehman, T.A., Iman, D.,
McMenamin, M., Sugimura, H., Weston, A., and Pfeifer, A., Oncogenes and
tumor suppressor genes involved in human lung carcinogenesis. Basic Life
Sci, 1990. 53: 363-79.
273. Weston, A., Willey, J.C., Modali, R., Sugimura, H., McDowell, E.M.,
Resau, J., Light, B., Haugen, A., Mann, D.L., Trump, B.F., and et al.,
Differential DNA sequence deletions from chromosomes 3, 11, 13, and 17 in
squamous-cell carcinoma, large-cell carcinoma, and adenocarcinoma of the
human lung. Proc Natl Acad Sci U S A, 1989. 86(13): 5099-103.
274. Ikeda, H. and Sugimura, H., Fv-4 resistance gene: a truncated
endogenous murine leukemia virus with ecotropic interference properties.
J Virol, 1989. 63(12): 5405-12.
275. Tsugane, S., Watanabe, S., Sugimura, H., Otsu, T., Tobinai, K.,
Shimoyama, M., Nanri, S., and Ishii, H., Infectious states of human T
lymphotropic virus type I and hepatitis B virus among Japanese immigrants
in the Republic of Bolivia. Am J Epidemiol, 1988. 128(5): 1153-61.
276. Wakabayashi, T., Mori, S., Pastolero, J., and Sugimura, H., Bile
ductal and ductular changes of the livers in the renal allografted patients.
Acta Pathol Jpn, 1987. 37(8): 1223-36.
277. Tsugane, S., Watanabe, S., Sugimura, H., Urano, Y., and Matsubara,
S., Recent trends in different histological types of lung cancer in Tokyo
based on pathological autopsy records. Jpn J Cancer Res, 1987. 78(2):
162-9.
278. Tsugane, S., Watanabe, S., Sugimura, H., Arimoto, H., Shimosato,
Y., and Suemasu, K., Smoking, occupation and family history in lung cancer
patients under fifty years of age. Jpn J Clin Oncol, 1987. 17(4): 309-17.
279. Sugimura, H., Watanabe, S., Tsugane, S., Morinaga, S., and Yoneyama,
T., Case-control study on histologically determined multiple primary lung
cancer. J Natl Cancer Inst, 1987. 79(3): 435-41.
280. Konishi, F., Wyse, N.E., Muto, T., Sawada, T., Morioka, Y., Sugimura,
H., and Yamaguchi, K., Peutz-Jeghers polyposis associated with carcinoma
of the digestive organs. Report of three cases and review of the literature.
Dis Colon Rectum, 1987. 30(10): 790-9.
281. Kawasaki, H., Shimada, H., Nakura, H., Sugimura, H., and Tomonaga,
M., Peculiar pattern of glial fibrillary acidic protein production in
extracranial metastatic tumor cells of malignant astrocytoma. Acta
Neuropathol, 1987. 74(1): 89-91.
282. Urano, Y., Ohmori, H., Sugimura, H., and Fukushima, T., [Behcet's
disease with Budd-Chiari syndrome. Apropos of a case. Review of cases
autopsied in Japan and of the literature]. Ann Pathol, 1986. 6(3): 192-6.
283. Sugimura, H., Tange, T., Yamaguchi, K., and Mori, W., Systemic
hemangiomatosis. Acta Pathol Jpn, 1986. 36(7): 1089-98.
284. Sugimura, H., Mohri, N., Urano, Y., Yamamoto, E., Kawana, T., and
Hagino, Y., A case report of mixed mesodermal tumor of the uterine cervix
(mixed, heterologous and homologous sarcoma of the uterine cervix). Jpn
J Clin Oncol, 1986. 16(4): 391-6.
285. Sugimura, H., Shiga, J., Urano, Y., and Mori, W., [Distribution of
hepatitis B surface antigen in the liver]. Nippon Shokakibyo Gakkai Zasshi,
1985. 82(11): 2769-74.