1001117_eus_hepatobiliary & gu system

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EUS教學 Hepatobiliary & GU System 陳國智醫師 新光醫院急診醫學科 輔仁大學醫學系 中華民國醫用超音波學會指導醫師 1

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Page 1: 1001117_EUS_Hepatobiliary & GU System

EUS教學

Hepatobiliary & GU System

陳國智醫師

新光醫院急診醫學科

輔仁大學醫學系

中華民國醫用超音波學會指導醫師

1

Page 2: 1001117_EUS_Hepatobiliary & GU System

臨床情境

• 65歲男性,突發性左側腰痛30分鐘,Severity 9/10,從左腰痛到左側睪丸處

• 請問你該怎麼辦 ?

• 急診超音波在此能提供什麼幫忙?

Page 3: 1001117_EUS_Hepatobiliary & GU System

臨床情境

• 49歲女性,糖尿病患者,發燒及左側腰痛二週,診所診斷為泌尿道感染,但患者對於口服抗生素反應不佳

• 請問你該怎麼辦 ?

• 超音波在泌尿道感染能提供什麼幫忙?

Page 4: 1001117_EUS_Hepatobiliary & GU System

正常的腎臟解剖及

超音波影像認識

[重要]

泌尿道系統包含雙側腎臟 + 膀胱

任何重點掃描都應包含兩個互補介面

Page 5: 1001117_EUS_Hepatobiliary & GU System

Compartments of the retroperitoneum

Page 6: 1001117_EUS_Hepatobiliary & GU System

Anatomic relationship of the kidneys

Page 7: 1001117_EUS_Hepatobiliary & GU System

Overview of kidney anatomy

Page 8: 1001117_EUS_Hepatobiliary & GU System

正常的腎臟解剖位置

• 腎臟位在後腹腔,T12 - L4

• 右腎低於左腎

• 右腎在肝和膽的後/下方

• 左腎在脾的內/下方

• 腎上腺在腎臟的上/前/內側

Page 9: 1001117_EUS_Hepatobiliary & GU System

Overview of kidney anatomy

• 長: 9-13 cm; 寬: 4-6 cm; 厚: 2.5-3.5 cm

• Gerota’s fascia: – 包覆kidney, capsule, perinephric fat

• Sinus – Hilum: vessels, nerves, lymphatics, ureter

– Pelvis: major and minor calyces

• Parenchyma surrounds the sinus – Cortex: site of urine formation, contains nephrons

– Medulla: contains pyramids that pass urine to minor calyces. Columns of Bertin separate pyramids

Page 10: 1001117_EUS_Hepatobiliary & GU System

Longitudinal ultrasound view of the

normal right kidney

Page 11: 1001117_EUS_Hepatobiliary & GU System

Transverse ultrasound view of the

normal right kidney

Page 12: 1001117_EUS_Hepatobiliary & GU System

Normal left kidney

Page 13: 1001117_EUS_Hepatobiliary & GU System

Normal filled urinary bladder

Page 14: 1001117_EUS_Hepatobiliary & GU System

Male Pelvis

Page 15: 1001117_EUS_Hepatobiliary & GU System

Prostate Enlargement

Page 16: 1001117_EUS_Hepatobiliary & GU System

Longitudinal images of normal right kidney

Page 17: 1001117_EUS_Hepatobiliary & GU System

Transverse image of normal right kidney

Page 18: 1001117_EUS_Hepatobiliary & GU System

腎臟之超音波影像

• 正常情況下看不到輸尿管 (Ureters)

• Pelvis: 看的到的時候呈現黑色影像

• Sinus: 因為脂肪所以呈現白色 (echogenic)

• Medullary pyramids: hypoechoic

• Cortex:

– mid-gray, less echogenic than liver or spleen.

• Capsule: smooth and echogenic

Page 19: 1001117_EUS_Hepatobiliary & GU System

重點式急診泌尿系統超音波

掃描注意事項

• 病患準備:

– 無

• 探頭: 3.0 ~ 3.5 MHz

– 瘦的人: 5.0 MHz

• 病患姿勢

– 平躺 (Supine)

– Posterior oblique,

lateral decubitus,

prone

I

LIVER STOMACH

IVC AORTA

K K

S

Page 20: 1001117_EUS_Hepatobiliary & GU System

重點式急診泌尿系統超音波之應用

?

Page 21: 1001117_EUS_Hepatobiliary & GU System

Clinical indications for EUS

• Acute flank pain/suspected renal colic

• Acute urinary retension

• Bladder size estimation

• Acute renal failure

• Complicated UTI (APN & renal abscess)

• Trauma

Page 22: 1001117_EUS_Hepatobiliary & GU System

Acute flank pain/

suspected renal colic

EUS重點:

懷疑有obstruction時

排除AAA時

Page 23: 1001117_EUS_Hepatobiliary & GU System

Acute flank pain/suspected renal colic

• 急性腹/腰痛和血尿的評估 – 懷疑腎絞痛 (renal colic)

– s/s: 腰陣痛合併鼠蹊部轉移

– 診斷工具: IVP v.s. US v.s Helical CT

• EUS的重點: – 有無阻塞,如hydronephrosis (2K1B都要掃)

– 要會辨識stone在超音波下的影像

– > 50y/o, 需同時排除AAA

• 進階掃描: – 阻塞物之定位及合併症

Page 24: 1001117_EUS_Hepatobiliary & GU System

Overview of degrees of hydronephrosis

Page 25: 1001117_EUS_Hepatobiliary & GU System

Mild Hydronephrosis

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Moderate Hydronephrosis

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Hydronephrosis with

acute calyceal rupture

Page 29: 1001117_EUS_Hepatobiliary & GU System

Dilated ureter below bladder

(transverse view)

Page 30: 1001117_EUS_Hepatobiliary & GU System

Algorithm

for renal colic

Page 31: 1001117_EUS_Hepatobiliary & GU System

Renal stone

EUS重點:

Hyperdense lesion with acoustic shadow

Page 32: 1001117_EUS_Hepatobiliary & GU System

Renal stone

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Renal stone

Page 34: 1001117_EUS_Hepatobiliary & GU System

Renal stone

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Renal stone

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Renal pelvis stone &

Hydronephrosis

Page 37: 1001117_EUS_Hepatobiliary & GU System

Ureteropelvic junction stone

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Ureterovescicular junction stone

Page 39: 1001117_EUS_Hepatobiliary & GU System

Renal cyst

EUS重點

1. smooth, round, or oval

2. no internal echo

3. well-defined margin

4. posterior enhancement

Page 40: 1001117_EUS_Hepatobiliary & GU System

Renal cyst

Page 41: 1001117_EUS_Hepatobiliary & GU System

Renal cyst

Page 42: 1001117_EUS_Hepatobiliary & GU System

Renal cyst

Page 43: 1001117_EUS_Hepatobiliary & GU System

Polycystic kidney

Page 44: 1001117_EUS_Hepatobiliary & GU System

Polycystic kidney

Page 45: 1001117_EUS_Hepatobiliary & GU System

Renal abscess

為什麼這不是simple renal cyst ?

Page 46: 1001117_EUS_Hepatobiliary & GU System

Bladder

• 解尿解不出來,要不要立刻導尿呢?

– Acute urine retension

• 小朋友要導尿留U/C,會不會failure ?

– Bladder size evaluation

Page 47: 1001117_EUS_Hepatobiliary & GU System

膀胱容積 (ml) =

長 * 寛 * 高 * 0.75 (error: 15-35%)

Bladder index volume (AP * Transverse) 2.4cm2 = 2ml

Page 48: 1001117_EUS_Hepatobiliary & GU System

Fungating bladder mass (拜託, 有obstructive uropathy一定要看UB)

Page 49: 1001117_EUS_Hepatobiliary & GU System

Acute renal failure

重點:

找有無post-renal obstruction

Page 50: 1001117_EUS_Hepatobiliary & GU System

Acute renal failure

• Pre-renal

– Kidney & IVC evaluation

• Intrinsic

– Difficult

• Post-renal

– Search obstruction

Page 51: 1001117_EUS_Hepatobiliary & GU System

Complicated UTI

(APN & renal abscess)

EUS應用重點時機

1. Risk factors

2. Treatment failure

3. Severe sepsis/septic shock

Page 52: 1001117_EUS_Hepatobiliary & GU System

Risk factors for complicated APN

• Elderly

• Male

• History of preexisting renal diseases

• Current use of catheters

• Previous renal calculi

• Diabetes mellitus

Chen KC, et al. AJEM (in press), doi:10.1016/j.ajem.2010.01.047

Page 53: 1001117_EUS_Hepatobiliary & GU System

50F, Septic shock

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50F, Peri-renal abscess

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50F, Peri-renal abscess

Page 57: 1001117_EUS_Hepatobiliary & GU System

Trauma

EUS重點

Highly operator dependent

若gross hematuria, 血行動力不穩or 危險機轉,仍應考慮CECT

Page 58: 1001117_EUS_Hepatobiliary & GU System

Renal trauma

Page 59: 1001117_EUS_Hepatobiliary & GU System

Subcapsular renal hematoma

(Trauma)

Page 60: 1001117_EUS_Hepatobiliary & GU System

57M, Post-ESWL

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Catheters

Page 62: 1001117_EUS_Hepatobiliary & GU System

Pitfalls

1. Bedside US is limited in scope

2. Hydronephrosis may be mimicked

3. Presence of hydronephrosis may be masked by dehydration

4. The absence of hydronephrosis does not rule out a ureteral stone

5. Patients with an acute AAA often present with flank pain

6. A bladder mass may be a hematoma

Page 63: 1001117_EUS_Hepatobiliary & GU System

臨床情境

• 30歲男性,半夜2點,上腹及右上腹悶痛至急診就診,理學檢查有Murphy’s sign

• 請問你該怎麼辦 ?

• 急診超音波在此能提供什麼幫忙?

Page 64: 1001117_EUS_Hepatobiliary & GU System

腻力激盪

急診超音波能應用在那些肝膽道疾病 ??

對急診臨床工作有何助益 ??

Page 65: 1001117_EUS_Hepatobiliary & GU System

重點式膽道超音波的臨床應用

• 對診斷膽結石為快速且正速的工具

• Ultrasonic Murphy’s sign和理學檢查有著相同的意義

• 快速且非侵入性

• 無放射或顯影劑暴露的影響

• 床邊執行

• Cost-effective procedure

Page 66: 1001117_EUS_Hepatobiliary & GU System

肝膽道圖示

Triangle of Calot

Page 67: 1001117_EUS_Hepatobiliary & GU System

患者準備

• 常規掃描: 空腹6-8小時

• 急重症患者不適用空腹原則

• 如果患者剛進食不久

– 膽囊會收縮變小

– 膽囊壁會變厚

• 注意: 急性病變時,膽囊通常因下列原因脹大

– Poor oral intake

– Abdominal pathology

– Biliary tract obstruction

Page 68: 1001117_EUS_Hepatobiliary & GU System

患者姿勢

• 起始姿勢: 平躺

• 利用兩種以上的姿勢的好處 – 對病灶有更好或更多面向的觀察

– 可以偵測stone or sludge的移動

• 其他姿勢 – Left or right lateral decubitus,

– Left posterior oblique

– Partially upright

Page 69: 1001117_EUS_Hepatobiliary & GU System

探頭的擺放

• 參考: – 個人偏好 & 經驗; 患者的體態

• 善用肝臟: acoustic window

• 擺放位置: – Anterior subcostal

– Coronal

– Right posterior oblique

• 觀察重點: the portal triad

Page 70: 1001117_EUS_Hepatobiliary & GU System

Longitudinal views of the gallbladder

Page 71: 1001117_EUS_Hepatobiliary & GU System

Transverse views of the gallbladder

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Intercostal views of the gallbladder

Page 73: 1001117_EUS_Hepatobiliary & GU System

Portal vein and normal common bile duct

Page 74: 1001117_EUS_Hepatobiliary & GU System

PV & CBD

Micky Mouse sign

Page 75: 1001117_EUS_Hepatobiliary & GU System

Hepatic venous system

Page 76: 1001117_EUS_Hepatobiliary & GU System

急診膽道系統超音波ACEP

• Primary: 辨識膽結石

• Extended:

–膽囊炎

– CBD異常: 擴張或結石

–肝異常: 腫瘤、膿瘍、pneumobilia

– Portal vein異常

–其他膽囊異常: 包含腫瘤

–黃胆

–腹水

Page 77: 1001117_EUS_Hepatobiliary & GU System

Clinical indications

• Gallstones and biliary colic

• Acute cholecystitis

• Jaundice and biliary duct dilatation

• Abdominal sepsis

• Ascites

• Hepatic abnormalities

Page 78: 1001117_EUS_Hepatobiliary & GU System

常見急診超音波應用

• 右上腹或上腹痛

–看有無結石

–看有無膽囊炎

• 黃胆

–看有無膽道阻塞

• 腹水

–看腹水,協助paracentesis

Page 79: 1001117_EUS_Hepatobiliary & GU System

掃描時回答的問題

• 有無膽結石

• 膽囊有無發炎 – Sonographic Murphy’s sign

– Impacted stone

– GB wall thickening

– Pericholecystic fluid

– Increased transverse GB diameter

• 有無CBD dilatation

Page 80: 1001117_EUS_Hepatobiliary & GU System

Biliary colic algorithm

80

Page 81: 1001117_EUS_Hepatobiliary & GU System

Gallstones 注意Acoustic shadow

Page 82: 1001117_EUS_Hepatobiliary & GU System

Polyp

Page 83: 1001117_EUS_Hepatobiliary & GU System

Polyps & Tiny stones 比較一下兩者的不同處

Page 84: 1001117_EUS_Hepatobiliary & GU System

膽囊炎臨床表現

• Fever

• Chills

• RUQ pain

• Leukocytosis

• Jaundice

• Positive Murphy’s sign

• Acalculous cholecystititis 1- 5 % –在急診壓這個診斷不是不可能,對的機率太小

Page 85: 1001117_EUS_Hepatobiliary & GU System

膽囊炎的超音波影像

• 膽結石 – 大多數患者有結石存在

– 如果沒有結石,要考慮acalculous cholecystitis.

• 膽囊橫徑 > 4-5 cm

• GB wall thickness (正常 < 3mm) > 4-5 mm (anterior wall)

– Averages 5 mm in acute cholecystitis

– Averages 9 mm in chronic cholecystitis

Page 86: 1001117_EUS_Hepatobiliary & GU System

膽囊炎: 其他超音波發現

• Decreased echogeneity of the entire wall

• Sonographic Murphy’s sign

• Pericholecystic fluid

• Diffuse, homogeneous echogeneity with GB

lumen (pus in lumen or GB empyema)

Page 87: 1001117_EUS_Hepatobiliary & GU System

Sonographic Murphy’s Sign

• 將探頭直接放在膽囊上並施壓

• 若這技巧重覆患者的症狀,高度指向有症狀的膽結石或急性膽囊炎

• 尋找其他指向阻塞或發炎的發現:

– Gallbladder wall thickening

– Increased transverse diameter of GB

– Pericholecystic fluid

Page 90: 1001117_EUS_Hepatobiliary & GU System

造成膽囊壁增厚的原因

• Present in many non-inflammatory conditions

– Post-prandial most common

– Congestive heart failure

– Starvation/hypoproteinemic states

– Ascites

– HIV

Page 91: 1001117_EUS_Hepatobiliary & GU System

WES sign

(wall echo shadow)

Page 92: 1001117_EUS_Hepatobiliary & GU System

CBD 掃描技巧Scanning Tips

• 請患者左側躺45度

• 掃描時,探頭和肋緣垂直

• 尋找portal vein最長的部份

• CBD應該就在portal vein的前方(螢幕上方)

• CBD和portal vein先交叉後平行

Page 93: 1001117_EUS_Hepatobiliary & GU System

Parallel channel sign

Page 95: 1001117_EUS_Hepatobiliary & GU System

Antler signs

Page 96: 1001117_EUS_Hepatobiliary & GU System

Mirizzi syndrome

Page 97: 1001117_EUS_Hepatobiliary & GU System

Cirrhosis of the liver

• Decreased liver size

• Increased

parenchymal

echogenicity

• Increased surface

irregularity

• Distorted intrahepatic

anatomy

Page 98: 1001117_EUS_Hepatobiliary & GU System

Bacterial peritonitis

Page 99: 1001117_EUS_Hepatobiliary & GU System

Hepatomegaly

Page 100: 1001117_EUS_Hepatobiliary & GU System

Splenomegaly

Page 101: 1001117_EUS_Hepatobiliary & GU System

Biliary sludge

Page 102: 1001117_EUS_Hepatobiliary & GU System

Contracted gallbladder

Page 103: 1001117_EUS_Hepatobiliary & GU System

Liver cyst

Page 105: 1001117_EUS_Hepatobiliary & GU System

Hemangioma

Page 106: 1001117_EUS_Hepatobiliary & GU System

Metastatic tumors

Page 107: 1001117_EUS_Hepatobiliary & GU System

GB stone

(變換掃描角度的重要意義)

Longitudinal view Intercostal oblique view

Page 108: 1001117_EUS_Hepatobiliary & GU System

Packed gallbladder

(容易被忽略的acoustic shadow)

Page 109: 1001117_EUS_Hepatobiliary & GU System

Cholecystitis ? Ascites

Page 110: 1001117_EUS_Hepatobiliary & GU System

Pitfalls

• Misidentifying the gallbladder

• Inadequate visualization of the gallbladder and biliary system

• Confusion with shadowing

• Misdiagnosing cholelithiasis and cholecystitis

• Misdiagnosing dilated intrahepatic ducts

• Misdiagnosing ascites

• Cystic Duct stone

• Common bile duct stones

• Misdiagnosis of Biliary Colic

Page 111: 1001117_EUS_Hepatobiliary & GU System

謝謝聆聽

歡迎指教及給予回饋

Juice119.pixnet.net

[email protected]

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