1002977 biotechnica 2010:layout 1 - deutsche messe agfiles.messe.de/cmsdb/d/079/23729.pdf · 1...

2nd BIO-IT World Europe

2nd Bio@venture Conference

Bioactive Ingredients for Functional Foods

Biotechnological Innovation in Food

bone-tec

GEN Drug Discovery Theatre

Innovation Forum

Life Science Spotlight

1st Molecular Diagnostics Europe

Partnering

2nd PEGS Europe

5th World Congress on Preventive and Regenerative Medicine

Conference

Program

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Veranstaltungen BIOTECHNICA 2010

Herzlich Willkommen zu den BIOTECHNICA Konferenzen!

Die Schwerpunkte in diesem Jahr: Bio/Pharma IT, molekulare Diagnostik, Proteine & Antikörpersowie präventive und regenerative Medizin, die sowohl in den Konferenzen im ConventionCenter als auch auf den Sonderpräsentationsflächen in der Halle 9 abgebildet werden.

Neben den Konferenzen erleben Sie in den Foren der Halle 9 weitere hochinteressanteVorträge. Besuchen Sie das neue GEN Drug Discovery Theatre, das alt bekannte INNOVATIONForum, das BMBF Projektforum Biotechnologie sowie das Life Science Spotlight. Im Übrigenwerden sich die Life Science Research Unternehmen erstmals auf einem Gemeinschaftsstandpräsentieren, auf dem die Exponate auf die jeweiligen Themen im Life Science Spotlight abge-stimmt sind.

Knüpfen Sie interessante und erfolgversprechende Geschäftskontakte in der Halle 9!

Events at BIOTECHNICA 2010

Welcome to BIOTECHNICA Conferences!

The topics to be addressed at this year's conferences and the parallel expo in Hall 9 areBio/Pharma IT, Molecular Diagnostics, Proteins, Antibodies, and Preventive & RegenerativeMedicine. For even more thematic coverage, Hall 9 will feature a rich array of forum lectures. Visit the GEN Drug Discovery Theatre, the BIOTECHNICA INNOVATION Forum, the BMBF Biotech ProjectForum and the Life Science Spotlight. For the first time, life science research firms will be presenting themselves within a joint pavilion, with exhibits reflecting the various "Life ScienceSpotlight" themes to be featured daily.

In short: besides the conferences in the convention center Hall 9 is the place to be for knowledge transfer, insight into new products and solutions and networking at its very best!

32

1st fl oor

ground fl oor

Convention Center (CC)Hall 9 Exhibition & Forums

54

TOPIC PROGRAM ORGANIZER OCTOBER WHERE CONDITIONS OF

PARTICIPATION4th 5th 6th 7th

MEDICAL BIOTECHNOLOGY Therapeutics 2nd PEGS Europe – Protein & Antibody Engineering Summit Cambridge Healthtech Institute (CHI) CC

5th World Congress on Preventive and Regenerative Medicine International Foundation Regenerative Medicine GmbH CC

bone-tec 2010 International Bone-Tissue-Engineering Congress

Institute Indente –10th

CC

EAPB SIG: Regenerative Medicine European Association of Pharma Biotechnology (EAPB) CC

EAPB SIG: Regulatory Aspects for Biopharmaceuticals European Association of Pharma Biotechnology (EAPB) CC

Stem Cells (Life Science Spotlight) Life Science Research (LSR) Hall 9, G61

Diagnostics 1st Molecular Diagnostics Europe Cambridge Healthtech Institute (CHI) CC

Forensics (Life Science Spotlight) Life Science Research (LSR) Hall 9, G61


AGRIFOOD BIOTECHNOLOGY

Food Analytics

& Production

Molecular Food Analysis (Life Science Spotlight) Life Science Research (LSR) Hall 9, G61

Biotechnological Innovation in Food MicroMol GmbH CC

Bioactive Ingredients for Functional Foods Forschungsverbund Agrar- und Ernährungs wissenschaften Niedersachsen (FAEN)Deutsches Institut für Lebensmitteltechnik e.V.

CC

INTERDISCIPLINARY TECHNOLOGIES

Bioinformatics 2nd Bio-IT World Europe Cambridge Healthtech Institute (CHI) CC

ENABLING TECHNOLOGIES

2nd PEGS Europe – Protein & Antibody Engineering Summit Cambridge Healthtech Institute (CHI) CC

2nd Bio-IT World Europe Cambridge Healthtech Institute (CHI) CC

1st Molecular Diagnostics Europe Cambridge Healthtech Institute (CHI) CC

Molecular Food Analysis (Life Science Spotlight) Life Science Research (LSR) Hall 9, G61


Forensics (Life Science Spotlight) Life Science Research (LSR) Hall 9, G61

Biobanks (Life Science Spotlight) Life Science Research (LSR) Hall 9, G61

SERVICES/BUSINESS DEVELOPMENT

2nd Bio@venture Conference 2010 Investitions- und Förderbank Niedersachsen, NBankLandesinitiative Life Sciences Niedersachsen, BioRegioNEnterprise Europe Network Niedersachsen, Deutsche Messe

CC

SPECIAL EVENTS

GEN Drug Discovery Theatre Genetic Engineering & Biotechnology News Hall 9, B23

BMBF Project Forum Biotechnology Bundesministerium für Bildung und Forschung (BMBF) Hall 9, C25

BIOTECHNICA PARTNERING Deutsche Messe, EBD Group Hall 9, C65

Posters and Exhibits BioIT, PEGS, Molecular Diagnostics Deutsche Messe, Cambridge Healthtech Institute (CHI) Hall 9, C54

Posters and Exhibits Regenerative Medicine Deutsche Messe, International Foundation Regenerative Medicine

Hall 9, E65

Latin American Day 2010 Lateinamerika Verein e.V. Pav. 37

BIOTECHNICA INNOVATION FORUM

BIOTECHNICA INNOVATION FORUM Deutsche Messe Hall 9, B49 and G61

CAREER DEVELOPMENT AND TRAINING

Award of the BIOTECHNICA Study Prize 2010 VBIO e. V., Roche Diagnostics GmbH Hall 9, E41

jobvector career day jobvector Hall 9, B53

For detailed information please visit: www.biotechnica.de/events

CC = Convention Center Hall 9 = BIOTECHNICA Exhibition Hall = registration and fee required = complimentary and no registration

jobvector-Check / jobvector-Checking Service...............................................................................................................56

jobvector-Forum.............................................................................................................................................................56

jobvector-Networking ....................................................................................................................................................58

Program Cambridge Healthtech Institute

Floor plan Convention Center (CC) ....................................................................................S–2

2nd Bio-IT World Europe .............................................................................................B2–B10

2nd Annual PEGS Europe ..........................................................................................P11–P20

Molecular Diagnostics Europe ................................................................................M21–M29

7

Medical Biotechnology

2nd PEGS Europe – Protein & Antibody Engineering Summit .......................................................................................8

5th World Congress of Preventive & Regenerative Medicine (WCPRM)......................................................................10

bone-tec 2010 – International Bone-Tissue-Engineering Congress...............................................................................18

EAPB SIG: Regenerative Medicine...............................................................................................................................25

EAPB SIG: Regulatory Aspects for Biopharmaceuticals ...............................................................................................26

Life Science Spotlight 2010 – Stem Cells ....................................................................................................................27

1st Molecular Diagnostics Europe ................................................................................................................................28

Agrifood Biotechnology

Life Science Spotlight 2010 – Molecular Food Analysis...............................................................................................29

Biotechnological Innovation In Food .............................................................................................................................30

Bioaktive Inhaltstoffe für funktionelle Lebensmittel / Bioactive Ingredients for functional Foods................................31

Interdisciplinary Technologies

2nd Bio-IT World Europe ...............................................................................................................................................33

Enabling Technologies

Life Science Spotlight 2010 – Forensics/Biobanks.......................................................................................................34

Services/Business Development

2nd Bio@venture Conference 2010...............................................................................................................................36

Special Events

Gen Drug Discovery Theatre .........................................................................................................................................38

BMBF Projektforum Biotechnologie / BMBF Project Forum Biotechnology.................................................................39

BIOTECHNICA PARTNERING .......................................................................................................................................45

Lateinamerika-Tag 2010 / Latin American Day 2010......................................................................................................46

BIOTECHNICA Innovation Forum

Innovation Forum ..........................................................................................................................................................48

Career Development & Training

Verleihung des BIOTECHNICA Studienpreises 2010 / Award of the BIOTECHNICA Study Price 2010........................55

jobvector-Karrierestand / jobvector Career Booth .........................................................................................................55

6

IKDT Innovative Diagnostics - Your Partner in Molecular ResearchIKDT Innovative Diagnostics as one of the first service providers in Europe offers the prompt access to two innovative technologies – GENIOM Biochips (FEBIT) and Taqman Low-Density-Arrays (Applied Biosystems) for gene expression studies or microRNA profiling. Applying bead-based Luminex technology our service portofolio includes additionally multiplex measurement of cytokine and immunological profiles, microRNA sets and transcriptome panels by test systems from different suppliers for research projects, clinical trials or molecular diagnostics.

Services provided:Gene expression analysis

(Affymetrix, Applied Biosystems)Whole genome array (FEBIT)SNP Genotyping by QPCR and Sequencing

(Applied Biosystems, BeckmanCoulter)MicroRNA profiling

(Applied Biosystems, FEBIT, Luminex)Phosphorylated proteins, cytokine profiling

(Biorad, Invitrogen)

Internet: www.innovative-diagnostics.eu

Visit us: Halle 009, Stand 26

Institute Cardiac Diagnostics and Therapy (IKDT)IKDT is a leading laboratory worldwide in differential diagnostics of viral infections and inflammation of heart muscle tissue following the interna-tional recommendations. IKDT is the only cardiological laboratory performing molecular diagnosics of endomyocardial biopsies in Germany which is accredited by College of American Pathologists (CAP) according to FDA guidelines. Customers for our biopsy diagnostics are hospital-affiliated institutions or private doctor offices. Four main topics will be covered for routine diagnostics:

Institut Kardiale Diagnostik und Therapie GmbHMoltkestrasse 31 , D-12203 Berlin (Germany)Phone: +49 (0) 30 8441 5540Fax: +49 (0) 30 8441 5555www.ikdt.com | email: [email protected]

we are in

HistologyImmunohistochemistryMolecular Virology Autoantibodies

The International Portal for DNA technology opens in December 2010. Register now in german or international registry

DNA24.netVisit: www.dna24.netTel.: +49 (0)35601-51451

More informations:Halle 009, Stand 26

and save pre-opening discount of more then 70%!www.dna24.net/biotechnica2010

Be in

2nd PEGS Europe – Protein & Antibody Engineering Summit

Convention Center (CC), Saal/room 1 A, Saal 1B/Room 1B

04.10.2010 – 07.10.2010

Due to last year’s success BIOTECHNICA and Cambridge Healthtech Institute (CHI) are again featuring an importantlife science conference.

At PEGS Europe 2010 delegates will hear over 50 presentations from international researchers, with the ability tomove between two concurrent tracks to attend presentations of specific interest to them. There are also numerousother learning and networking opportunities ranging from Pre-Conference Short Courses to networking receptionsand other social events. Programs:– Novel Antibody Constructs and Alternative Scaffolds – Protein Expression and Cell Line Development – Empowered Bispecific Antibodies and Antibody-Drug Conjugates – Difficult Protein Expression and Purification

Details for this conference: pages P11–20

Cambridge Healthtech Institute250 First AvenueUSA–02494 Needham

English

Participation fee incl. V.A.T. and entrance tickets to the fair Attendance of TWO conferences:1.745,00 EUR (Commercial)

805,00 EUR (Academic, Government, Hosp. Affiliated)450,00 EUR (Student)

Attendance of ONE conference:1.245,00 EUR (Commercial)


Registration required via Cambridge Healthtech Institute’s online atwww.PEGSummitEUROPE.com

On-site Registration (4-7 October, 2010):Convention Center (CC), Foyer Area 1, Registration desk.

Jennifer DevineTelefon: +1 781-972-5400Fax: +1 781-972-5425E-mail: [email protected]

Kontakt/Contact

Teilnahme/Participation

Sprache/Language

Veranstalter/Organizer

8


10


Dienstag/Tuesday, 05.10.2010

Convention Center (CC), Room 2:

Opening

Welcome Address and Official Opening

Hauke Jagau, President of Hannover Region

Presidential Address:

The Future of Regenerative Medicine

William Haseltine, Haseltine Associates, Haseltine Foundation, Washington, USA

Commercialization in Regenerative Medicine

Linda Powers, Toucan Capital, Bethesda, USA

Coffee Break Foyer Area Convention Center

Official “Rebirth” Lecture: Hepatocyte Transplantation – a Clinician’s Viewpooint

Michael Manns, Medizinische Hochschule Hannover (MHH), Hannover, Germany

Bionic Technologies for Stem Cell Therapies– Physiology, preclinical and clinical studies

Augustinus Bader, Biomtechnological-Biomedical Center (BBC), University of Leipzig, Leipzig,Germany

Rudolf-Pichlmayr Honorary Lecture:

Preventive and Regenerative Medicine – the EU Role in Addressing Public Health Challenges

John Dalli, European Commissioner for Health and Consumer Policy, European Commission,Brussels, Belgium

Lunch & Poster Viewing, hall 9


Session 1: Stem Cell Mechanisms – Keynotes

Hans-Günther Machens, Georg Duda

Crosstalk Between Immune Cells and Stem Cells

Hans-Dieter Volk, Charité Berlin, Berlin, Germany

New Regenerative Tools for Chronic Wounds

Hans-Günther Machens, Technische Universitat München; Klinikum rechts der Isar, Munich,Germany

Bone Regeneration

Georg Duda, Charité Berlin, Berlin, Germany

Session 1: Stem Cell Mechanisms – Short Presentations

Hans-Günther Machens, Georg Duda

Stem Cells and Organ Transplantation – Telomerase Activity:

Indicator for Stable Transformation Efficiency in Mesenchymal Stem Cells

Gökhan Duruksu

Veterinary Requirements for Stem Cell Therapy – Isolation and Immunophenotypic

Characterization of Equineperipheral Blood-Derived Mesenchymal Stem Cells: Preliminary

Results

Armando de Mattos Carvalho

Stem Cell Therapy for All Tissue Types

Maria Beatriz Herrera Sanchez

08:30–09:00

14:00–15:00

Moderation:

13:40–14:00

13:20–13:40

13:00–13:20

Moderation:

12:00–13:00

11:30–12:00

11:00–11:30

10:30–11:00

10:00–10:30

09:30–10:00

09:00–09:30

11


5th World Congress of Preventive & Regenerative Medicine (WCPRM)

Convention Center (CC), Room 2, 3A

05.10.2010–07.10.2010

BIOTECHNICA has brought the 5th World Congress for Preventive and Regenerative Medicine (WCRM) toHannover. Having previously been hosted in Leipzig and Bangkok, this major scientific event will take place for thefirst time at the European summit for biotechnology and the life sciences.

During BIOTECHNICA scientists and clinical experts from all over the world will be meeting to discuss new ways oftreating previously untreatable or therapeutically challenging diseases with regenerative therapies.

The program reflects the broad spectrum of scientific approaches in regenerative medicine. In view of the scientificcontent of this year’s program, emphasis is being placed on preventive medicine. Further keynote themes include tis-sue engineering, clinical applications of regenerative medicine, anti-aging medicine and stem cell research. Stem cellsare thought to have huge potential in the treatment of a number of chronic diseases. Due to the statutory restrictionson research into the field of regenerative medicine, ethical and legal aspects will also rank high on the agenda.

International Foundation Regenerative Medicine gGmbHWorld Federation & World Virtual Institute of Preventive & Regenerative Medicine, Sanamander(TM) in concunction with BIOTECHNICA

Englisch/English

Full conference ticket (5-7 October 2010)500,00 EUR (Participants)400,00 EUR (Members)200,00 EUR (Students)200,00 EUR (Exhibitors)

Two-day conference ticket400,00 EUR (Participants)320,00 EUR (Members)160,00 EUR (Students)160,00 EUR (Exhibitors)

One-day conference ticket200,00 EUR (Participants)160,00 EUR (Members)80,00 EUR (Students) 80,00 EUR (Exhibitors)

Full admission to BIOTECHNICA 2010, Lunch and coffee breaks during the World Congress, Nametag and delegate bags, Abstract book or CD.No VAT requested according to §4.22 UStG (Participation fee/coffee breaks)Registration required online at http://regmed.net/registration/

On-site Registration (5-7 October, 2010):Convention Center (CC), Foyer Area 2, Registration desk

Dana SchlameußTelefon: +49 6182 – 94 666 16Fax: +1 781-972-5425E-mail: [email protected]

Kontakt/Contact


Sprache/Language


5th World Congress of Preventive & Regenerative Medicine (WCPRM)

13


12


In vivo Evaluation of Carbon Nanotube Incorporated Poly (L-lactic acid) Aligned Nanofibrous

Scaffold for Peripheral Nerve Regeneration

Mahboubeh Kabiri

Influence of Nickel Ions on Human Multipotent Mesenchymal Stromal Cells

Tim Habijan

New Sample Preparation Methods for Soft Tissue, Hard Tissue and Biomaterials

Fabian Will

Evaluation of In Situ-Forming Chitosan/Starch Hydrogel for Retaining Chondrocyte

Function: In vivo Study

Jarupa Viyoch

Suppressed Cascular Calcification in the Porcine Acellular Bioscaffolds Prepared by

Ultra High Pressure Treatment

Tetsuji Yamaoka

Convention Center (CC), Room 3 A:

Session 3: Translational Regenerative Medicine – Requirements and Innovation – Keynotes

Linda Powers, Alex Zhavronkov

EU Research Agenda on Regenerative Medicine

Prof. Dr. Arnd Hoeveler, Head of Unit “Biotechnology for Health”, European Commission (DG Research), Brussels, Belgium

Analytical Standardization (GLP)

Arnold Raem, Arrows Biomaterials Deutschland GmbH, Muenster, Germany

Translational Medicine – From Bench to Bed

Rita Dobmeyer, Galenus – G.H. AG, Basel, Switzerland

Good Clinical Practice (GCP)

Uwe Breyer, Galenus – G.H. AG, Basel, Switzerland

Diabetic Foot – Incidence and Current Treatment, Potential for Innovation

Gernot-Rainer Storm, Diabetologische Gemeinschaftspraxis, Lehrte, Germany

Mittwoch/Wednesday, 06.10.2010


Session 5: Bone and Cartilage Regeneration (Orthopedics, Trauma and Maxillofacial Surgery) – Keynotes

Jörg Wiltfang, René van Weeren

Stem Cell Based Augmentation of the Jaws

Jörg Wiltfang, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Kiel, Germany

Potential of Endogenous Regenerative Technology for in situ Regenerative Medicine

Gorka Orive, IMASD, Vitoria, Spain

A Zonal Approach to Articular Cartilage Repair

René van Weeren, Utrecht University, Utrecht, The Netherlands

Session 5: Bone and Cartilage Regeneration (Orthopedics, Trauma and Maxillofacial Surgery) – Short

Communications

Jörg Wiltfang, René van WeerenModeration:

09:10–09:30

08:50–09:10

08:30–08:50

Moderation:

16:15–16:30

16:00–16:15

15:45–16:00

15:30–15:45

Moderation:

16:30–16:45

Isolation, Characterization and Ex Vivo Expansion of Stem Cell Like Population from

Healthy Rat Adult Liver with their Multilineage Potential in a Clinically Relevant Bioreactor

Shibashish Giri

In-vivo Model for Tissue Engineering of Peripheral Defects of Onferior Alveolar Nerve (IAN)

with Solid Tissue, Stem Cells and Growth Factors in Artificial Bunger-Bands

Jörg Heine

Coffee Break (Foyer Area Convention Center)


Session 2: Biomaterials & Stem Cells – Keynotes

Feng-Huei Lin, Frederico Calegari

Thermo-sensitive Hydrogel as Cell Carrier for Nucleus Pulposus Regeneration

Feng-Huei Lin, National Taiwan University, Taipei, Taiwan

Inducible Expansion of Neural Stem Cells in the Adult Mammalian Brain

Frederico Calegari, DFG-Forschungszentrum und Exzellenzcluster für Regenerative Therapien(CRTD), Dresden, Germany

Session 2: Biomaterials & Stem Cells – Short Communications

Feng-Huei Lin, Frederico Calegari

Valve Interstitial Cells Growth and Differentiation upon Porous Collagen I Scaffold under

Static and Dynamic Culture Conditions for Heart Valve Tissue Engineering

Frantisek Straka

Growth Factor and Cytokine Expression of Human Mesenchymal Stromal Cells Is Not

Altered in an In Vitro Model of Tissue Damage

Katrin Montzka

Pancreativ Islets Protected by Pancreatic Islet Derived Stem Cells through Cytokines

Gökhan Duruksu

Ex vivo Expansion of Urothelial Cells in Tridimensional Scaffolds

Regina Avelina de Moraes da Silva

Endocytosis, Intracellular Distribution and Exocytosis of Silver Nanoparticles in Human

Mesenchymal Stem Cells

Christina Greulich

Biomaterials, Effects of Hydroxyapatite Nanoparticles in Mesenchymal Stem Cells –

Investigation of Cytotoxicity and Genotoxicity

Huiying Chung

TGFb1 / Affinity-bound Alginate Scaffold Enhances Chondrogenic Differentiation of Human

Mesenchymal Stem Cells (HMSC)

Tali Re`em

Nanofibrous Surface Effect on Neuronal Differentiation of MSC`s

Ismet Gurhan

The Effects of Hydrostatic Pressure on the Gene Expression in Smooth Muscle Cells Grown

on Polymer Scaffolds

Hana Hanaee Ahvaz

Modification of Gelantin Structure with Cholesterol for Curcumin Delivery

Sorada Kanokpanont

16:10–18:00

Moderation:

15:50–16:10

15:30–15:50

Moderation:

15:00–15:30

5th World Congress of Preventive & Regenerative Medicine (WCPRM) 5th World Congress of Preventive & Regenerative Medicine (WCPRM)


Session 5: Bioartificial Organs – ESAO Meeting – Keynotes

Bart Meyns, Birgit GlasmacherUpcoming Challenges of Mechanical Support in Chronic Heart Failure

Bart Meyns, Gasthuisberg University Hospital, Leuven, Belgium

Cell based or Cell free Nano Scaffolds for Cardiovascular Regeneration

Beat Walpoth, HUG University Hospital, Geneva, Switzerland

Requirements for the Treatment of Uremic Patients with the Artificial Kidney

Jörg Vienken, Fresenius Medical Care GmbH, Bad Homburg, Germany

Nanostructured Biomaterials – a Successful Way for Extracorporeal Adsorption Therapy in

Sepsis and Liver Failure

Dieter Falkenhagen, Donau-Universität Krems, Krems, Austria

Scaffolds, Tracer and Depots for Engineering and Bioprinting of Tissues

Birgit Glasmacher, Leibniz Universität Hannover, Hannover, Germany

PANEL DISCUSSION WITH THE ESAO BOARD


Session 6: Novel Technologies and Models – Keynotes

Henry Su, Eckard WolfLong Life Platelet Technologies

Henry C.Y. Su, National Yang-Ming University, Taipei, Taiwan

Transgenic Large Animal Models for Regenerative Medicine

Eckard Wolf, Ludwig-Maximilians Universität München, Munich, Germany

Session 6: Novel Technologies and Models – Short Communications

Henry Su, Eckard Wolf

Synergetic Effects of Rotational Culture and BMP2 Stimulation on Scaffold-free Cartilage

Formation

Katsuko Furukawa

Successful Closure of Fetal Membrane Defects Using Manufactured, Decellularized Human

Amnion Membrane after Fetoscopy in the Midgestational Rabbit Model

Nikolaos Papadopulos

Endocultivation: 3D Printed Customized Porous Scaffolds for Heterotopic Bone Induction

Stephan Becker

Periadventitial Wrap Releasing Sirolimus Prevented Intimal Hyperplasia in a Rabbit Model

Elena Filova

Veterinary Requirements for Stem Cell Therapy Studies of Efficacy Procedures to Assure

Stem Cells Vitality During Cryopreservation and Shipment

Tiziana Martinello

In-vivo Vascularisation of Fibre-based Scaffolds Biofunctionalised with Adult Mesenchymal

Stem Cells

Timo Hammer

Microvesicles from Mesenchymal Stem Cells Protect against Acute Kidney Injury and

Improve Survival

Stefania Bruno

11:40–13:00

Moderation:

11:20–11:40

11:00–11:20Moderation:

12:15–12:30

12:00–12:15

11:45–12:00

11:30–11:45

11:15–11:30


15


14


Use of Adipose Tissue-derived Mesenchymal Stem Cells for Experimental Tendinitis Therapy

in Equines

Armando de Mattos Carvalho

Scaffold-free Cartilage Tissue by Mechanical Stress Loading for Tissue Engineering

Stephanie Yin Wai Ting

Regeneration of Joint Cartilage Achived with Madu Treatment in Patients with

Degenerative Diseases of Joints

Dusanka Mandic

Cartilage Regeneration in Patients with Rheumatoid Arthritis

Jelena Popovic

The Synergistic Effects of Lysophosphatidic Acid Receptor Agonists and Calcitriol on MG63

Osteoblast Maturation at Titanium and Hydroxyapatite Surfaces

Maryam A. Nowghani

Biomaterials – Nano-Organised Silica Material with Improved Bioactivity

Aránzazu Diaz-Cuenca

Seperation and Characterization of Osteoprogenitors from the Entire Periosteum-derived

Tissue

Marcus Olbrich


Session 4: Ontogenesis, Neurogenesis, Neural Repair, Spinal Cord Injury/Genetics, Epigenetics,

Engineering – Keynotes

Michael Brand, Lukas Sommer

Regeneration of the Adult Zebrafish Brain: Towards Endogenous Stem Cell based Repair in

a Vertebrate Brain

Michael Brand, Technische Universität Dresden, Dresden, Germany

Multipotent Neural Crest Stem Cells in Development and Disease

Lukas Sommer, University of Zurich, Zurich, Switzerland

Session 4: Ontogenesis, Neurogenesis, Neural Repair, Spinal Cord Injury/Genetics, Epigenetics,

Engineering – Short Communications

Michael Brand, Lukas Sommer

Neutral Differentiation of Mouse Embryonic Stem Cells Seeded on Nanofibrous CNT-

incorporated Scaffolds

Mahboubeh Kabiri

Long Term Bone Regeneration by Engineered Mesenchymal Stem Cells

Sophia Chia-Ning Chang

Spinal Cord Regeneration – Injectable Hydrogel-based Formulations for Spinal Cord

Regeneration

Anne des Rieux

Nasal Septum Derived Progenitors: Isolation, Characterization and Multi-lineage

Differentiation Potential

Shafiee Abbas

Coffee Break (Foyer Area Convention Center)10:30–11:00

09:40–10:30

Moderation:

09:20–09:40

09:00–09:20

Moderation:

09:30–10:30


17


Lunch / Poster Viewing (Hall 9)


Session 7: Rejuvenation Biotechnologies: Applying Regenerative Medicine to Aging – Keynotes

Aubrey de Grey, Rita Dobmeyer

Applying of Regenerative Medicine to Aging: Many Targets and Techniques, Unprecedented

Impact (Presidential Keynote)

Aubrey de Grey, Methuselah Foundation, Cambridge, United Kingdom

Prevention in Pharmacotherapy

Jürgen Frölich, Medizinische Hochschule Hannover (MHH), Fraunhofer Institut ITEM, Hannover,Germany

DANI (Dynamic Antaging Nutritional Intervention): a Novel Hormetic Strategy for Antiaging

Intervention and Rejuvenation

Ettore Bergamini, University of Pisa, Pisa, Italy

Advanced Lipoxidation and Glycoxidation in Aging: Therapeutic Prospects for the Inhibitors

Cimen Karasu, Gazi University, Ankara, Turkey

The Role Exercise Plays in Prevention and Therapy of Cardiovascular Diseases

Martin Halle, Technische Universität München, Klinikum rechts der Isar, Munich, Germany

Session 7: Rejuvenation Biotechnologies: Applying Regenerative Medicine to Aging – Short Communications

Aubrey de Grey, Rita Dobmeyer

Oxidative Stress, Apoptosis and Aging

Nihat Dilsiz

Anti-Aging Medicine – The Lymphatic System and Postural Stress. New Strategy of Anti-

Aging Medicine

Olga Safonicheva

Donnerstag/Thursday, 07.10.2010


Session 9: Scaffolds & Differentiation – Keynotes

Loredana de Bartolo, Axel Neffe

Polymeric Membranes for Guiding Neuronal Regeneration

Loredana De Bartolo, National Research Council of Italy, ITM-CNR, Rende, Italy

Fishing for Stem Cells – New Ways for Generating in Vivo Self-Endothelializing Surfaces for

Blood Contacting Implant

Hans -Peter Wendel, Universitätsklinikum Tübingen, Tübingen, Germany

Biomaterials for Regenerative Therapies

Axel Neffe, GKSS-Forschungszentrum Geesthacht GmbH, Teltow, Germany

Session 9: Scaffolds & Differentiation – Short Communications

Loredana de Bartolo, Axel NeffeFunctional Differentiation and Expansion of Rat Embryonic Liver Cells on Biodegradable

and Synthetic Membranes

Carla Campana


09:40–10:00

09:20–09:40

09:00–09:20

Moderation:

12:30–14:00

14:30–15:00

Moderation:

15:00–15:30

17:00–17:30

Moderation:

16:30–17:00

16:00–16:30

15:30–16:00

16


Non Invasive Observation of the Ultrastructure and the Mechanical Properties in hMSCS by

Acoustic Microscopy

Cornelia Hildebrandt

Novel Cell Technologies for Stem Cells

Tobias May

The Effects of Nano Scale on Satellite Cells Proliferation and Differentiation Potential

Symzar Hosseinzadeh

Superporous Poly(ethylene glycol) Diacrylate Scaffolds Support Differentiation of Human

Mesenchymal Stem Cells

Melanie Köllmer

Combination of Chitosan Tubular Bioprosthesis and Fetal Oesophagus Graft for

Oesophagus Plasty (Early Observations)

Very Coulic


Session 8: Regulatory Affairs – Keynotes

Ian Rees, Ralf Sanzenbacher

European Regulatory Policy in Regenerative Therapies

Ian Rees, Medicines and Healthcare Products, Regulatory Agency, London, United Kingdom

Regenerative Therapies: Current Challenges and Regulatory Requirements from a Member’s

State Point of View

Ralf Sanzenbacher, Paul-Ehrlich-Institut, Federal Institute for Vaccines and Biomedicines, Langen,Germany

Manufacturing Excellence in GMP and Biotechnology

David Estape, M+W Process Industries GmbH, Stuttgart, Germany

Session 8: Regulatory Affairs – Short Communications

Ian Rees, Ralf Sanzenbacher

Principles of Cleanroom Technology – Why Cleanroom Technology Is Crucial for

Regenerative Medicine

Peter Novak

GMP Requirements and Regulatory Affairs From A Practitioner’s Perspective

Carsten Schewe

Coffee Break (Foyer Area Convention Center)


Session 10: Stem Cells: From Bench to Therapy – Keynotes

Paolo Macchiarini, Herwig GutzeitIterative Process of Stem Cell Product Development for Therapy

Ralf Huss, Roche Diagnostic GmbH, Prenzberg, Germany

Airway Tissue Engineered Replacement and Cell Therapy

Paolo Macchiarini, University of Florence, Florence, Italy

Biology of Gonial Stem Cells in Fish

Herwig Gutzeit, Technische Universität Dresden, Dresden, Germany11:40–12:00

11:20–11:40


10:30–11:00

09:55–10:30

Moderation:

09:40–09:55

09:25–09:40

09:00–09:25

Moderation:


Donnerstag/Thursday, 07.10.2010, 14:00–20:00 Uhr/hrs

Convention Center (CC), Saal/room 3:

Welcoming Address

Dr. Karl-Heinz Schuckert, Congress Chair

SYMPOSIUM 1: Physical Stimuli Can Enhance BMP Activities

Prof. h.c. PD Dr. Franz E. Weber

Physical Stimuli Can Enhance BMP Activities

Prof. h.c. PD Dr. Franz E. Weber, University Hospital Zurich, Dept. Cranio-Maxillofacial Surgery,Switzerland

SYMPOSIUM 2: Tissue Engineering and Beyond: Embedding Osteogenic Molecular Signals into ‘Smart’

Biomimetic Matrices Initiating Bone: Formation by Autoinduction

Prof. Dr. Ugo Ripamonti

Tissue Engineering and Beyond: The Spontaneous Induction of Bone Formation by

Macroporous Self-Inducing Biomimetic Matrices

Prof. Dr. Ugo Ripamonti, University of the Witwatersrand, Bone Research Unit MRC,Johannesburg, South Afica

Self-Inducing Biomimetic Matrices and Prefabricated Osteogenic Protein-1/Coral-derived

Biomimeitc Implants as Vasculariized Pedicled Flaps for Craniomandibulofacial Tissue

Engineering in Human Patients

Dr. Carlo Ferretti, University of the Witwatersrand, Bone Research Unit, Johannesburg, South Africa

Topographical Macroporous Surface Modifications by Osteoclastogenesis Initiate the

Spontaneous Induction of Bone Formation by Calclium Phosphate-based Biomimetic

Matrices

Prof. Dr. Ugo Ripamonti, University of the Witwatersrand, Bone Research Unit MRC,Johannesburg, South Afica

Coffee Break

Convention Center (CC), Saal/room 3 A:

Oral Presentations: Bone Regeneration I (concurrent sessions)

Prof. Dr. Ashraf Ayoub; Prof. Dr. Hae-Ryong Song

Human Osteoblasts and Their Progenitors: Discovery of New Molecular Targets and Support

Biomaterials for Bone Tissue Regeneration

Mrs. Roberta Piva, Mrs. Roberta Piva, University of Ferrara, Dept. of Biochemistry and MolecularBiology, Italy

Tetracyclines as Biomodulators in Bone Tissue Regeneration

Mr. Pedro Gomes, University of Porto, Faculty of Dental Medicine, Laboratory of Pharmacologyand Cellular Biocompatibility, Portugal

Bone Regeneration after Implantation of Nanoparticulate Hydroxyapatite and Collagen

Type-1 in Osteoporotic Goats

Mrs. Katrin S. Lips, University of Giessen, Dept. of Trauma Surgery, Germany

Polychrome Sequence Labeling for the Investigation of Bone Remodeling Activity of

Different Magnesium Alloys

Mrs. Janin Reifenrath, University of Veterinary Medicine Hannover, Small Animal Clinic, Germany

17:15–17:30

17:00–17:15

16:45–17:00

16:30–16:45

Moderation:

16:00–16:30

15:40–16:00

15:20–15:40

15:00–15:20

Moderation:

14:15–15:00

Moderation:

14:00–14:15

19


18


Session 10: Stem Cells: From Bench to Therapy – Short Communications

Paolo Macchiarini, Herwig GutzeitTissue Regeneration in Madu-treated Patients with Arterial Disease of the Lower

Extremites

Slobodan Kazic

Variability in MSC Surface Markers Expression Depending on Umbilical Cord Sample and

Amount of Ex vivo Passages

Olena Deryabina

Asymptomatic Bacterial Biofilm Communities on Rhythm Management Devices Differ

Considerably from Virulent Ones

Wolf-Rainer Abraham

Histological Evaluation of Urothelial Adhesion Cells from Rabbit Bladder in Heterologous

Acellular Matrix as Scaffold for Implantation in Rabbit Urethra

Priscilla Murador

Optimal Materials for Urological Tissue Engineering

Katrin Montzka

Evaluation of the CellTiter-Blue Assay for Cell Growth Analysis of Human Embryonic Stem

Cells During Cultivation

Eva Woenne

Closing Ceremony

bone-tec 2010 – International Bone-Tissue-Engineering CongressConvention Center (CC), Saal/room 307.10.2010–10.10.2010

Der Kongress bone-tec 2010 gilt in Fachkreisen als der führende Kongress zur Knochenregeneration in der Welt.Dies kommt auch dadurch zum Ausdruck, dass das gesamte Editorial Board des International Tissue EngeneeringJournals in diesem Jahr auf dem bone-tec Kongress zu Gast sein wird und in einem Round Table zusammen mitdem wissenschaftlichen Board von bone-tec und einigen eingeladenen Wissenschaftlern von Rebirth (MHH) überdie Notwendigkeit der internationalen Vernetzung der Forschungszentren diskutieren wird.Wie in den vergangenen Jahren werden führende Wissenschaftler aus allen Kontinenten in Hannover ihre neustenErgebnisse präsentieren. Ein besonderes Augenmerk der Kongressveranstalter gilt der Förderung derNachwuchswissenschaftler. Die beiden von der Jury als beste Young Scientists ausgezeichneten werden mitStipendien prämiert werden, die ihnen die Möglichkeit einräumen einige Monate zu Gast bei einem der führendenWissenschaftler der Welt zu sein. Darüber hinaus werden der jeweils beste Vortrag und das beste Poster mit nennenswerten Preisen dotiert.

This congress joins leading scientists from all over the world in modern bone regeneration, including cartilage, tendons and ligaments. Latest and progressive research results will be presented. Established research teams willreport on their work. In addition the congress should initiate cooperation, expand networks and create the planningof future projects.

bone-tec 2010 would like to honour outstanding young scientists who have presented orally or in poster during thecongress. The award will entitle young scientists to be hosted by our keynote speakers for training/research and teaching within their institutes/laboratories/clinics. The place of internship will be offered in direct relevance to thescientist’s research interest and that of the hosting institute/laboratory/clinic.

Institute INDENTEEllernstr. 23D–30175 Hannover


13:15–13:30


5th World Congress of Preventive & Regenerative Medicine (WCPRM) bone-tec 2010 – International Bone-Tissue-Engineering Congress

Characterization of Native Salmon Collagen for Application in Bone Tissue Regeneration

Mrs. Ines Stachel, Research Institute for Leather and Plastic Sheeting (FILK), Freiburg, Germany

The Effect of Surface Biomimetic Apatite Nanostructure of Chitosan/Nano-hydroxyapatite

Scaffold on Protein Adsorption and Osteogenic Differentiation of Rat Bone Marrow Stem

Cells

Mr. Guancong Wang, Shandong University, State Key Lab of Crystal Material, Jinan, China

In Vitro Biomimetic Mineralization of Native Three-Dimensional Collagen Framework

for Bone Tissue Engineering Scaffold

Mr. Hongshi Zhao, Shandong University, Jinan, China

Opening Ceremony – Poster Presentation, Greetings, Get Together

Freitag/Friday, 08.10.2010, 09:00–19:15 Uhr/hrs


Special Presentations

The Induction of Bone Formation by the Mammalian Transforming Growth Factor-ß

Proteins: Apparent Redundancy and Biological Activities; Craniomandibulofacial

Reconstruction in Non-Human Primates Papio Ursinus

Prof. Dr. Ugo Ripamonti, University of the Witwatersrand, Bone Research Unit MRC,Johannesburg, South Afica; Dr. Carlo Ferretti, University of the Witwatersrand, Bone ResearchUnit, Johannesburg, South Africa

High Resolution CT for 3D-Analysis of Biomedical Materials

Mr. Frank Sieker, GE Sensing & Inspection Technologies, Wunstorf, Germany

Coffee Break / Poster Presentation

Main Programme

Tissue Engineering of Equine Matrix-Associated Allogenous Chondrocyte Transplants

(MACT) – an In Vitro Study

Prof. Dr. Walter Brehm, University of Leipzig, Faculty of Veterinary Medicine, Large Animal Clinicfor Surgery, Germany

Stem Cells, Growth Factors and Natural Biomaterials for Bone Engineering

Prof. Dr. Martijn van Griensven, Ludwig Boltzmann Institute for Experimental and ClinicalTraumatology, Austrian Cluster for Tissue Regeneration, Vienna, Austria

Bone Material Quality in Osteoporosis and in Bone Regeneration

Prof. Dr. Peter Fratzl, Max Planck Institute of Colloids and Interfaces, Dept. of Biomaterials,Potsdam, Gemany


Cell Culture Studies on Polymers for Bone Tissue Engineering

Prof. Dr. C. James Kirkpatrick, University Medical Center Johannes Gutenberg University, REPAIR-lab, Institute of Pathology, Mainz, Germany

Quality Management in Bone Tissue Engineering – How to Prove New Bone Growth

Dr. Karl-Heinz Schuckert, Institute Indente, Hannover, Germany

Lunch / Poster Presentation

First Results Using Concentrated Mesenchymal Stem Cells to Reconstruct Bone Defects

Dr. Ulf-Joachim Gerlach, BUK Hamburg, Dept. of Septic Bone and Joint Surgery, Hamburg,Germany

18:30–18:45

14:00–14:30

13:00–14:00

12:30–13:00

12:00–12:30

11:30–12:00

11:00–11:30

10:30–11:00

10:00–10:30

18:45–19:00

19:00–19:15

19:15–20:00

09:45–10:00

09:30–09:45

09:00–09:30

21


20


Evaluation of Degradation Behaviour and Biocompatibility of the Magnesium Alloy Zek100

by Use of In-Vivo Micro Computed Tomography

Mrs. Dina Rittershaus, University of Veterinary Medicine Hannover, Small Animal Clinic, Hannover,Germany


Repair of a Critical-Sized Cranial Defect with a Biodegradable PEG-Tetra-Norbornene

Polymer Scaffold Encapsulating rhBMP-2

Mr. Sven-Olrik Streubel, University of Colorado, The Children’s Hospital Denver, Dept. ofOtolaryngology, Aurora, Colorado, USA

Interactions between Bone and Titanium New Insights into the Unique Marriage

between Metal and Biology

Mr. Axel Wirthmann, New York University, College of Dentistry, Dept. Implantology, USA

Developing an Off-The-Shelf Tissue Engineering Strategy with Using Highly Angiogenic and

Osteogenic Human Fetal Mesenchymal Stem Cells and a Biaxial Rotating Bioreactor

Mr. Zhiyong Zhang, National University of Singapore, BIOMAT, Singapore

Bone Regeneration in a Canine Cranial Defect Model Using Allogeneic Osteo-Differentiated

Adipose Derived Stem Cells with in Vitro Immunosuppressive Property

Mr. Lei Cui, Shanghai Jiao Tong University, School of Medicine, China

Opening Ceremony – Poster Presentation, Greetings, Get Together

Convention Center (CC), Saal/room 3 B:Oral Presentations: Scaffolds and Matrices (concurrent sessions)

Prof. Dr. Yasuhiko Tabata; Prof. Dr. Swee-Hin Teoh

Tuning the Mechanical Properties of Bioreducible Multilayer Films for Improved Cell

Adhesion and Transfection Activity

Mrs. Jennifer Blacklock, Max Planck Institute, Dept. of Colloids and Interfaces, Berlin, Germany

Reconstruction of Femoral Epiphysis with Two Different Types of Scaffolds: Preliminary Results

Mr. Nicolandrea Del Piccolo, University of Bologna, Rizzoli Orthopaedic Institute, Orthopaedic andTraumathologic Surgery Clinic I, Italy

Comparison of Six Bone-Graft Substitutes: Efficiency, Metabolism and Growth Behaviour of

Human Mesenchymal Stem Cells in Vitro

Mr. Johannes Frank, Wolfgang Goethe University, Frankfurt am Main, Dept. of Trauma, Hand, &Reconstructive Surgery, Germany

A Novel Method for Controlling Pore Geometry, Size and Distribution in Engineered

Scaffolds and Its Effects on Cell Attachment, Proliferation and Differentiation

Mr. Alan Kop, Royal Perth Hospital, Dept. of Medical Engineering and Physics, Perth, Australia

Magnetic Biomimetic Scaffold for a Controlled Spatial Distribution of Cells Saturated with

Magnetic Nanoparticles

Mr. Alessandro Russo, University of Bologna, Rizzoli Orthopaedic Institute, Italy


Implantation of a Novel Synthetic, Biodegradable Scaffold for Meniscus Tissue Regeneration

Mr. Peter Verdonk, Ghent University Hospital, Belgium

Osteogenic Differentiation of Primary Stem Cells with BMP-2 in a Rotating Bed Reactor

Mrs. Stefanei Böhm, Leibniz University Hannover, Institute of Technical Chemistry, Germany

17:30–17:45

18:15–18:30

18:00–18:15

17:45–18:00

17:30–17:45

17:15–17:30

17:00–17:15

16:45–17:00

16:30–16:45

17:45–18:00

18:00–18:15

Moderation:

19:15

18:45–19:00

18:30–18:45

18:15–18:30

bone-tec 2010 – International Bone-Tissue-Engineering Congress bone-tec 2010 – International Bone-Tissue-Engineering Congress

Convention Center (CC), Saal/room 3:Oral Presentations: Bone Regeneration II (concurrent sessions)

Prof. Dr. Peter ten Dijke; Dr. Stefan Jopp

Repair of Critical Bone Defect in a Rabbit Model by Autologous Adipose-Derived Stem Cells

Mrs. Elena Arrigoni, University of Milan, Dept. of Medical Pharmacology, Italy

Injectable Hybrid Hydrogels for Bone Regeneration

Mrs. Matilde Bongio, Radboud University Nijmegen Medical Center, Dept. of Biomaterials, The Netherlands

Effect of Strontium on Human Primary Bone Cells

Mr. Julien Braux, CHU de Reims, INSERM UMR-S 926’, France

Role of Extracellular Calcium in Bone Tissue Regeneration through CaSR

Mrs. Arlyng González Vázquez, The Institute for Bioengineering of Catalonia, Barcelona, Spain

Biological Response of Human Osteoblasts to Ferritic Stainless Steel Surfaces

Mrs. Vera N. Malheiro, University of Cambridge, Dept. of Engineering, UK

Effects of Electron-Beam Irradiation to the Hydroxyapatite and Tricalcium Phosphate

Mixtures for the Development of New Synthetic Bone Substitutes

Mr. Jung M. Park, Seoul National University, College of Dentistry, Dept. of Oral and MaxillofacialSurgery, Korea

Osteoblast Mechanical Stimulation by Converse Piezoelectric Effect

Mrs. Joana Reis, University of Évora, Dept. of Veterinary Medicine, Portugal

Samstag/Saturday, 09.10.2010, 09:00–19:15 Uhr/hrs


Shaping the Microenvironment of Umbilical Cord-derived Mesenchymal Stem Cell-like

Cells for Bone Tissue Engineering

Mrs. Ass. Prof. Dr. Cornelia Kasper, Leibniz University Hannover, Institute of Technical Chemistry,Germany

Developing Strategies for Bone Regeneration to Remodelling

Prof. Dr. Swee-Hin Teoh, National University of Singapore, Dept. of Mechanical Engineering,NUSTEP, BIOMAT, Singapore

Silicate/Starch-Poly-ɛ-Caprolactone Microparticles with BMP-2 Induce Bone Regeneration

Mrs. Dr. Elizabeth Rosado Balmayor, University of Minho, 3B’s Research Group, Dept. of PolymerEngineering, Portugal


Success and Failures of BMP, TCP Scaffolding and Mesenchymal Stem Cells for Oro-Facial

Reconstruction

Prof. Dr. Ashraf Ayoub, Glasgow University, Biotechnology & Craniofacial Research Group, UK

Bone Substitute (ß-TCO) vs. Autologous Bone for Repair of Alveolar Clefts in Patients

with Cleft of Lip, Alveolus and Palate (CLP)

Dr. Ad P. de Ruiter, University Medical Centre, Dept. of Oral and Maxillofacial Surgery, Utrecht,The Netherlands


17:30–17:45

17:15–17:30

Moderation:

12:00–12:15

11:30–12:00

11:00–11:30

10:30–11:00

10:00–10:30

09:30–10:00

09:00–09:30

18:45–19:00

18:30–18:45

18:15–18:30

18:00–18:15

17:45–18:00

23


22


Complex Tissue

Prof. Dr. Clemens A. van Blitterswijk, University Twente, Faculty of Science and Technology, MIRA,The Netherlands

Advances in Long Bone Tissue Engineering

Prof. Dr. Hae-Ryong Song, Korea University, College of Medicine, Dept. of Orthopaedic Surgery,Seoul, Korea


Tissue Engineering Technology for Biosignaling Molecules in Bone Regeneration

Prof. Dr. Yasuhiko Tabata, Kyoto University, Institute for Frontier Medical Sciences, Field of TissueEngineering, Dept. of Biomaterials, Japan

Bone Regeneration Procedures for Predictable Function and Aesthetics in Oral Implantology

Prof. Dr. Gintaras Juodzbalys, Kaunas University of Medicine, Dept. of Maxillofacial Surgery,Lithuania


Convention Center (CC), Saal/room 15/16:Oral Presentations: Other Topics (concurrent sessions)

Dr. Elizabeth Rosado Balmayor; Prof. Dr. John A. Jansen

Differential Release of Human Soluble Receptors and Related Proteins in Mineralizing

Versus Non-Mineralizing Jaw Periosteal Cells

Mrs. Dorothea Alexander, University Hospital Tübingen, Germany

One- and Two-Step Seeding Protocols of Porcine Chondrocytes on a Three-Dimensional

ß-Tricalciumphosphate Matrix

Mr. Gregor Hauschild, Small Animal Clinic Menzel, Recklinghausen, Department of Orthopedicsand Tumor Orthopedics, University Hospital Muenster, Germany

Primary Stability of an Osteochondral Autograft Stabilized with a Resorbable

Osteoconductive Bone Cement

Mr. Marc-Oliver Kiss, University of Montreal, Imaging and Orthopedic Research Laboratory (LIO),Canada

Bone Engineering with Dental Pulp Mesenchymal Stem Cells (DPMSC): Laser Assisted

Differentiation to Osteoblasts

Mr. Vinicius Marchiori-Silva, University of São Paulo, IPEN Nuclear and Energetic ResearchInstitute, Brazil

Availing Bone Morphogenetic Protein: Expressing Recombinant Human BMP-2 as Codon

Optimized Cassettes in Transgenic Rice

Mr. George Styles, University of Ottawa, Biochemistry, Microbiology and Immunology Dept., Canada

Assessment of Stimulated Collagen Synthesis and Maturation in Osteoblast Cultures in

Cell Sheets and on Scaffolds

Mrs. Joanna Wójtowicz, Medical University of Warsaw, Poland

Human Knee Meniscal Cells: Characterization of Their Primary Culture and Response to

Biomimetic Surfaces in 2D and 3D Growth Environments

Mrs. Guak-Kim Tan, The University of Queensland, AIBN Australian Institute for Bioengineeringand Nanotechnology, Brisbane, Australia

Injectable Scaffold with Sustained rhBMP-2 Delivery for Bone Regeneration

Mrs. Asme Boussahel, University of Nottingham, Wolfson Centre for Stem Cells, TissueEngineering and Modelling (STEM), UK

14:30–15:00

15:00–15:30

15:30–16:00

16:00–16:30

17:00–17:15

16:30–17:00

17:30–17:45

17:15–17:30

Moderation:

19:00–19:15

18:45–19:00

18:30–18:45

18:15–18:30

18:00–18:15

17:45–18:00

bone-tec 2010 – International Bone-Tissue-Engineering Congress bone-tec 2010 – International Bone-Tissue-Engineering Congress

EAPB SIG: Regenerative Medicine

Convention Center (CC), Saal/room 17

04.10.2010, 13:30–17:30 Uhr/hrs

Advanced Therapy Medicinal Products (ATMPs) – die neuen Therapie-Methoden sind von der Europäischen Behördefür Medizin (European Medicines Agency, EMA) in London streng reguliert, um Sicherheit, Wirksamkeit und guteQualität zu gewährleisten.Ziel ist eine gute Risiko-Abwägung, um den ganzen Entwicklungsprozess, Qualitäts- und Sicherheits-Risiken abzu-schätzen. Hierbei geht es um die Möglichkeit der Entstehung von Tumoren, um die Stabilität des Genoms, sowiedie Biodistribution: diese gilt es für Stammzell-basierte Produkte früh abzuklären. Um Rückschläge bei derEntwicklung zu vermeiden, ist eine frühe Kommunikation mit der Behörde von Vorteil.Der “Scientific Advice” kann also ein hilfreiches, gutes Werkzeug sein, um sich im Dickicht von Richtlinien,Reflection Papers und Regularien sowie Erwartungen der Behörde zurechtzufinden.

Advanced Therapy Medicinal Products (ATMPs) are tightly regulated by the European Medicines Agency (EMA) withthe intention to ensure the safety, efficacy as well as the good quality of the products.A well defined risk evaluation in order to cover the whole development process and not only quality or safety risksshould be set-up. For example, tumorigenicity, genome stability, biodistribution are now among the top issuesduring non-clinical and clinical development and need to be addressed for stem cell-based products early. A keypoint is hereby an efficient communication with the regulators as early as possible to avoid detours or even worstfailures.So the scientific advice became a very powerful tool to find the right way through the jungle of guidelines, reflecti-on papers, regulations and the expectation of the regulators.

European Association of Pharma Biotechnology (EAPB)in Zusammenarbeit mit: Deutsche Messe

Englisch/English

Participation fee (no VAT requested according to § 4.22 UStG).50,00 EUREAPB SIG Member150,00 EUR Non-Member

Registration required via Deutsche Messe online at www.biotechnica.de/regenerative_medicine

Dr. Marion KronabelTelefon: +49 6221 3893985Fax: +49 6221 3893768E-mail: [email protected]

Montag/Monday, 04.10.2010Introduction: SIG Regenerative Medicine – targets

Dr. Joachim Nöller, Translational Centre for Regenerative Medicine, Leipzig, Germany

Scientific Advice – essential for Small and Medium sized Enterprises and academia in

Europe?

Dr. Jens Reinhardt, Paul Ehrlich Institute, Langen, Germany

“Do´s and Don´ts during Scientific Advise”

Dr. Gabriele Dallmann, Pharmatching GmbH, Freiburg, Germany

Coffee Break

Challenges in the Non-Clinical Development of Cell Based Therapies

Dr. Monika Chabicovsky, MC Toxicology Consulting, Vienna, Austria

Questions and answers – open discussion, brainstorming about focus for next SIG meeting


Sprache/Language


16:30–17:00

15:45–16:30

14:30–15:15

13:45–14:30

13:30–13:45

Kontakt/Contact

15:15–15:45

25


The Bone Regenerative Effect of Platelet-Rich Plasma

Prof. Dr. John A. Jansen, Raboud University Nijmegen Medical Center, Dept. of Biomaterials, TheNetherlands

Changes in Bone Material with Aging and Diseases

Prof. Dr. Mark Grynpas, University of Toronto, Bone and Mineral Group, Canada

Lunch / Poster Presentation

Hurdles in Tissue Engineering/Regenerative Medicine – Product Commercialization

A Survey of North American Academia and Industry

Prof. Peter C. Johnson, Scintellix, LLC, Raleigh NC, US

Controlling Osteoblast Differentiation and Bone Formation by BMP

Prof. Dr. Peter ten Dijke, Leiden University Medical Center, Dept. Molecular Cell Biology, TheNetherlands

Mimetic Biofabrication of Osteoinductive Nanomaterials for Repair of Craniofacial Defects

Prof. Dr. Paul Gatenholm, Chalmers University of Technology, Biopolymer Technology, Dept. of Chemical and Biological Engineering, Göteborg, Sweden


Advancing Biomaterial Strategies for Bone Tissue Engineering

Prof. Dr. Antonios G. Mikos, Rice University, Dept. of Bioengineering, Houston, Texas, US

Comparative Study of BMPs and Delivery Strategies

Prof. Dr. Ulf ME Wikesjö, Medical College of Georgia School of Dentistry, Laboratory for AppliedPeriodontal & Craniofacial Regeneration LAPCR, Augusta, US


Oral Presentations of the 10 best Poster Contributions

Congress Dinner and Presentation of Awards

Sonntag/Sunday, 10.10.2010, 10:00–12:00 Uhr/hrs

Convention Center (CC), Saal/room 15/16:

Students Workshop

Mrs. Dr. Elizabeth Rosado Balmayor

12:15–12:45

14:30–15:00

14:00–14:30

13:15–14:00

12:45–13:15

10:00–12:00

20:00

17:00–18:00

16:45–17:00

16:15–16:45

15:45–16:15

15:30–15:45

15:00–15:30

24


bone-tec 2010 – International Bone-Tissue-Engineering Congress

27


26


Topic 2: Aggregates and Particulate matter in Biopharmaceuticals

The US perspective on aggregates and subvisible/visible particles – review from recent

Breckenridge conference on aggregates and immunogenicity

Karoline Bechtold-Peters, Boehringer Ingelheim, Biberach, Germany

Immunogenicity of Therapeutic Proteins

Brigitte Brake, Federal Institute for Drugs and Medical Devices (BfArM), Bonn, Germany

Discussion

Participants are encouraged to forward short case studies and questions which will be

discussed within the SIG group

Life Science Spotlight 2010 – Stem Cells

Halle/hall 9, Stand/booth G61, (platform Innovation Forum)

06.10.2010, 12:00–14:00 Uhr/hrs

Die Life Science Research Unternehmen (LSR), die im Verband der Diagnostica Industrie organisiert sind, werdensich wieder auf der BIOTECHNICA 2010 präsentieren.

Die LSR Unternehmen sind Hersteller von Instrumenten und Reagenzien im Life-Science-Research-Bereich die sichzusammengeschlossen haben, um ihre Interessen gemeinsam zu vertreten. Sie verstehen sich als kompetenteGesprächspartner auf wissenschaftlicher, wirtschaftlicher, politischer und Anwenderebene. Eines der Ziele ist dieSchaffung von Plattformen für den Austausch und die Diskussion forschungsrelevanter Themen auch unterEinbeziehung ethischer und rechtlicher Fragen.

All the Life Science Research companies (LSR) that are organized in the German Association of Diagnostics Industrywill present themselves again at BIOTECHNICA 2010.

These LSR companies are manufacturers of instruments and reagents in the field of Life-Science Research. Theyhave joined forces to present their common interests. They understand themselves as qualified conversational part-ners on an academic, economic, political and operational level. One of their goals is to create a communication plat-form for the exchange and discussion of research relevant topics, taking into account ethical and legal questions.They will stage a series of manufacturer-independent noontime lectures with a strong scientific focus. The verylatest research topics will once again be presented by users, for users.

Fachabteilung Life Science Research im Verband der Diagnostica-Industrie e.V.Neustädtische Kirchstr. 8D–10117 Berlin

Deutsch/German or Englisch/English

Teilnahme kostenfrei in Verbindung mit einer Messeeintrittskarte.Participation free of charge to BIOTECHNICA ticket holders.

Dr. Markus HerbortTelefon: +49 151 180 12 485E-mail: [email protected]


Stem Cells

Melanie Steffens, Serva Electrophoresis GmbH

Characterization of human testes biopsies and isolation of spermatogonial stem cells

Dr. Nina Kossack, Centrum für Reproduktionsmedizin und Andrologie, Universitätsklinik Münster

Nabelschnurblut in der regenerativen Medizin

Dr. Verena Reimann, Institut für Transplantationsdiagnostik und Zelltherapeutika an derUniversitätsklinik Düsseldorf

17:00–17:30

16:15–17:00

15:30–16:15


12:00–12:30English

Moderation:

Kontakt/Contact


Sprache/Language

12:30–13:00Deutsch

EAPB SIG: Regulatory Aspects for Biopharmaceuticals

Convention Center (CC), Saal/room 18

04.10.2010, 13:30–17:30 Uhr/hrs

Biopharmazeutische Forschung und Entwicklung ist stark durch nationale und internationale Regularien beeinflusst,so dass die Entwickler und Hersteller von biopharmazeutischen Wirkstoffen sich mit den aktuellen Regularien her-vorragend auskennen müssen.Die regulatorischen Vorschriften wiederum müssen der wissenschaftlichen Realität Rechnung tragen. Dies ist einGleichgewicht, das am besten durch kontinuierlichen Austausch zwischen Industrie, Forschung und Behördegewährleistet werden kann.

Ziel des Arbeitsgruppen ist es, die Experten aus Behörden, Industrie und Forschung zu einem weiterenErfahrungsaustausch zusammenzuführen und die unterschiedlichen Standpunkte zu den Themen “Quality byDesign” und “Subvisible Partikel” auszutauschen.

In contrast to many other sciences, the biopharmaceutical sciences are heavily impacted by national and internatio-nal regulations so that developers and manufacturers of biopharmaceutical drug substances and drug products needprofound knowledge of the current drug regulations in the field as well as of current regulatory opinions.On the other hand, drug regulations must consider what is scientifically feasible and sensible. This balance is achieved the best by frequent exchanges between industry, academia and regulatory bodies.

The SIG Regulatory Aspects for Biopharmaceuticals wants to give this exchange room and targets at taking up cur-rent hot topics in presentations and discussion forums. The aim of this workshop is to bring together experts onregulation and experts from academia and industry in order to share experiences and discuss different opinions ontwo selected current hot topics: “Quality by Design” and “Subvisible Particles”.

European Association of Pharma Biotechnology (EAPB)in Zusammenarbeit mit: Deutsche Messe

Englisch/English

Participation fee (no VAT requested according to § 4.22 UStG).50,00 EUREAPB SIG Member Regenerative Medicine150,00 EUR Non-Member

Registration required via Deutsche Messe online atwww.biotechnica.de/regulatory_aspects_biopharmaceuticals

Dr. Marion KronabelTelefon: +49 6221 3893985Fax: +49 6221 3893768E-mail: [email protected]

Montag/Monday, 04.10.2010

Introduction: SIG Regulatory Aspects in Biopharmaceutical Development and Manufacture

Dr. Karoline Bechtold-Peters, Boehringer Ingelheim, Biberach

Topic 1: Practise of Quality by Design Approaches

Targeted development of biosimilar pharmaceutical products

Thomas Stangler, Sandoz Biopharmaceuticals, Kundl, Austria

New Variation Regulation 1234/2008 – classification and procedures

Maren von Fritschen, Pharmalex Berlin, Germany

Coffee Break


Sprache/Language


13:45–14:30

13:30–13:45

Kontakt/Contact

15:15–15:30

14:30–15:15

Therapeutische Einsatzmöglichkeiten von Stammzellen des Fettgewebes

PD Dr. rer. nat. et med. habil. Kirsten Peters, Department of Cell BiologyBiomedical Research Center Rostock

Stammzellen als aktiv integrierender Teil von Implantaten

Frau Anja Richter, Graduate School for Computing in Medicine and Life Sciences(Exzellenzinitiative der DFG) der Universität zu Lübeck ausgeführt am Fraunhofer EMB in Lübeck

1st Molecular Diagnostics Europe

Convention Center (CC), Saal/room Berlin, Saal Dresden/Room Dresden

04.10.2010–07.10.2010

For the first time BIOTECHNICA and Cambridge Healthtech Institute (CHI) are featuring an important life scienceconference.

Molecular diagnostic tools continue to drive biomedical research. Technological advances from next-generationsequencing, microarrays, quantitative PCR, microfluidics and POC enable speed, enhance sensitivity, and reducecosts. Cancer and infectious disease two diagnostic applications with widespread clinical impact are the mainemphasis for Molecular Diagnostics Europe.

Programs – Moving Molecular Diagnostics from Bench to Bedside – NGS: The Ultimate for Molecular Diagnostics – Point-of-Care Diagnostics

Details for this conference: pages M21–M29


English

Participation fee incl. V.A.T. and entrance tickets to the fair Attendance of TWO conferences:1.745,00 EUR (Commercial) 805,00 EUR (Academic, Government, Hosp. Affiliated)450,00 EUR (Student)



Registration required via Cambridge Healthtech Institute’s online atwww.MolecularDiagnosticsEU.com


Jennifer DevineTelefon: +1 781-972-5400Fax: +1 781-972-5425E-mail: [email protected]

13:30–14:00Deutsch

13:00–13:30Deutsch

Sprache/Language



Kontakt/Contact

28


Life Science Spotlight 2010 – Molecular Food Analysis

Halle/hall 9, Stand/booth G61, (platform Innovation Forum)/

(platform Innovation Forum)

05.10.2010, 12:00–14:00 Uhr/hrs









Dienstag/Tuesday, 05.10.2010Molecular Food Analysis

Hr Mittendorf, Thermo Fisher Scientific

Analytik von Lebensmitteln mit massenspektrometrischen Methoden

Dr. Thorsten Bernsmann, Chemisches und Veterinäruntersuchungsamt Münsterland-Emscher-Lippe

Food Authenticity Testing Using DNA Lab-on-a-Chip Capillary Electrophoresis

Steve Garrett, Campden BRI

Mikrobiologische Lebensmittelsicherheit im Zeitalter der Globalisierung

Herr Dr. Matthias Kuhn, CONGEN Biotechnologie GmbH Berlin

Mikrobiologische Untersuchungen mit Hybriscan im Dienstleistungslabor

Dr. Helmut Maucher, Becit GmbH

Einsatz der Real-Time PCR in der Lebensmittelanalytik, Erfahrungen in der laufenden

Routine

Dr. Daniel Dietrichs, Deutsches Institut für Lebensmitteltechnik e.V.

13:36–14:00Deutsch

13:12–13:36Deutsch

12:48–13:12English

12:24–12:48English

12:00–12:24Deutsch

Moderation:

Kontakt/Contact


Sprache/Language


29


LECTURE “GESETZLICHE AUFLAGEN UND SICHERHEIT”

Europäische Gesetzgebung: Fortschrittsbehinderung für die Lebensmittelproduktion?

Prof. Dr. Klaus-Dieter Jany, Vorsitzender CEF-Panel EFSA

Kaffeepause

Aromen, Enzyme und Zusatzstoffe: Gesetzliche Auflagen und Kennzeichnungsvorschriften

Prof. Dr. Moritz Hagenmeyer, Kanzlei Krohn Rechtsanwälte, Lehrbeauftragter Lebensmittelrecht anden Universitäten HH und H

Sicherheit von Lebensmitteln aus gentechnisch veränderten Organismen

Dr. Marianna Schauzu, Kommission für genetisch veränderte Lebensund Futtermittel, BfR

Bioaktive Inhaltstoffe für funktionelle Lebensmittel

Bioactive Ingredients for functional Foods

Convention Center (CC), Saal/room Heidelberg

06.10.2010, 14:00–17:00 Uhr/hrs

Netzwerk Lebensmittel – Vom hochwertigen Rohstoff zur gesunden ErnährungDas Netzwerk Lebensmittel ist ein gemeinsames Vorhaben von niedersächsischen Forschungseinrichtungen mitdem Ziel, hochwertige bioaktive Inhaltstoffe für die Herstellung funktioneller Lebensmittel zu erhalten. Es beginntmit der Gewinnung der Inhaltstoffe aus heimischen Rohstoffen und verläuft entlang der Nahrungskette bis zurHerstellung qualitativ hochwertiger Lebensmittelprodukte.Damit wird zur Sicherung der Wettbewerbsfähigkeit der niedersächsischen Lebensmittelindustrie durchNeuorientierung an dem Trend zu Lebensmitteln mit gesundheitlichem Zusatznutzen beigetragen.

Food network – From high-quality raw material to health nutritionThe food network is a joint project of research institutes from Lower Saxony aiming to obtain bioactive ingredientsof high quality for the production of functional foods. Starting with the production of ingredients from domestic rawmaterials, the project proceeds along the food chain up to the manufacture of high-quality healthy food products.Thus, the competitiveness of the Lower Saxony’s food industry is ensured by new orientation towards the tendencyof food with a health added benefit.

Forschungsverbund Agrar- und Ernährungswissenschaften Niedersachsen (FAEN)

Deutsch/German

Teinahme kostenfrei in Verbindung mit einer Messeeintrittskarte. Aus organisatorischen Gründenbitten wir Sie, uns ihre Teilnahme mitzuteilen.Registrierung online unter www.verbundprojekt1-faen.de

Elke SchoneTelefon: +49 5431 183-229Fax: +49 5431 183-200E-mail: [email protected]

Mittwoch/Wednesday, 06.10.2010Das Netzwerk Lebensmittel in Niedersachsen

Dr.-Ing. Volker Heinz, Deutsches Institut für Lebensmitteltechnik e.V., Quakenbrück

Hochwertige Proteine und Peptide aus Kartoffelfruchtwasser

Isabelle Schönbeck, Institut für Technische Chemie, Gottfried Wilhelm Leibniz UniversitätHannover

14:10–14:30

14:00–14:10

Kontakt/Contact


Sprache/Language


16:45–17:30

16:00–16:45

15:45–16:00

15:00–15:45

31


30


Biotechnological Innovation in Food

Convention Center (CC), Saal/room Frankfurt

05.10.2010, 09:00–17:30 Uhr/hrs

Fortschritt in der Lebensmittelproduktion

Das Fachsymposium richtet sich an Entscheidungsträger aus allen Bereichen der Lebensmittelproduktion, die ihreProduktpalette mit innovativen Produkten zukunftsfähig machen und neue Wege einschlagen möchten. Es gilt allenFührungskräften, die verantwortlich sind für Zielkonzeption, Produktentwicklung, Qualitätsmanagement, Analytik oderForschung & Entwicklung und Interessierte aus der Lebensmittelüberwachung. Für biotechnologisch arbeitendeUnternehmen gibt das Fachsymposium einen Einblick in den Lebensmittelmarkt, dessen Möglichkeiten und Grenzen.

MicroMol GmbHHedwigstr. 2-8D–76199 Karlsruhe

in Zusammenarbeit mit: Deutsche Messe

Deutsch/German

Teilnahmegebühr inkl. Seminarunterlagen, Teilnahmezertifikat, Pausenverpflegung undMesseeintrittskarteLebensmittelindustrie EUR 350,00 (zzgl. gesetzl. MwSt.)Universität/Hochschule/Behörde EUR 250,00 (zzgl. gesetzl. MwSt.)Student EUR 80,00 (zzgl. gesetzl. MwSt.).

Anmeldung erforderlich per Fax unter:Deutsche MesseKongressmanagementFax: +49 511 89 30998

Dr. Andrea B. DreuschTelefon: +49(0)721 9415213Fax: +49(0)721 9415214E-mail: [email protected]

Dienstag/Tuesday, 05.10.2010Registrierung

Eröffnung durch den Chairman

Prof. Dr. Klaus-Dieter Jany, Vorsitzender CEF-Panel EFSA

LECTURE “NEUE PRODUKTE MIT BIOTECH”

Probiotik/Praebiotik

Dr. Michael DeVrese, Institut für Physiologie und Biochemie der Ernährung, Max Rubner-Institut,Karlsruhe

Kaffeepause

Biotechnologische Methoden für haltbare und

sichere Lebensmittel – Chancen und Grenzen

Dr. Dieter Elsser-Gravesen, ISI Food-Protection ApS, Arhus, Dänemark

Enzymtechnologie – neue Wege zu besseren Lebensmitteln

Prof. Dr. Holger Zorn, Institut für Lebensmittelchemie und Lebensmittelbiotechnologie, Justus-Liebig-Universität Gießen

Mittagspause und Gelegenheit zum Besuch der Messe13:00–15:00

12:00–13:00

11:15–12:00

10:45–11:15

09:45–10:45

09:30–09:45

09:00–09:30

Kontakt/Contact


Sprache/Language


33

Interdisciplinary Technologies

Anthocyane aus farbfleischigen Kartoffeln – Farbstoffe und Antioxidantien

Dr. Silke Hillebrand, Institut für Lebensmittelchemie, Technische Universität Carolo-Wilhelmina zuBraunschweig

Hochwertige Oligosaccharide für Ernährung und Pharmazie

Prof. Dr. Hans-Joachim Jördening, Lehrstuhl für Technologie der Kohlenhydrate. TechnischeUniversität Carolo-Wilhelmina zu Braunschweig

Pause

Bioaktive Wirkprinzipien aus niedersächsischen Speisepilzen

Prof. Dr. Dr. R. G. Berger, Institut für Lebensmittelchemie, Gottfried Wilhelm Leibniz UniversitätHannover

Planung und Durchführung von Humanstudien für die Zulassung von “Health Claims”

Prof. Dr. Andreas Hahn, Institut für Lebensmittelwissenschaft und Humanernährung, GottfriedWilhelm Leibniz Universität Hannover

Zusätzliche Wertschöpfung durch Gewinnung von Rapsölen mit hohem Vitamin-E-Gehalt

Dr.-Ing. Knut Franke, Deutsches Institut für Lebensmitteltechnik e.V., Quakenbrück

Tocotrienole aus Biertreber: die niedersächsische Version des “neuen” Vitamin E

Dr. Astrid Drotleff, Institut für Lebensmitteltoxikologie und Chemische Analytik, StiftungTierärztliche Hochschule Hannover

16:40–17:00

16:20–16:40

16:00–16:20

15:40–16:00

15:10–15:40

14:50–15:10

14:30–14:50

32


2nd Bio-IT World Europe

Convention Center (CC), Saal/room 13/14, Saal 15/16/Room 15/16

04.10.2010 – 07.10.2010

Due to last year’s success BIOTECHNICA and Cambridge Healthtech Institute (CHI) are again featuring an importantlife science conference.

Managing the data deluge through data driven discovery. The 2nd Annual Bio-IT World Conference & Expo EUROPEevent features best practice case studies relevant to the technologies, research, and regulatory issues of life sci-ence, pharmaceutical, clinical and IT professionals.

Tracks: – IT Infrastructure & Informatics: Data Storage, Analysis and Visualization – NGS Data Management: Sequencing Systems, Storage, and Analysis – IT Infrastructure & Informatics: Collaborative Software, Standards and Web Technologies – Data Integration & Knowledge Management

Details for this conference: pages B2–B10


English

Participation fee incl. V.A.T. and entrance tickets to the fair Attendance of TWO conferences:1.745,00 EUR (Commercial)




For more information and registration please visitwww.Bio-ITWorldExpoEurope.com


Chris WatermanTelefon: +1 781-972-5400Fax: +1 781-972-5425E-mail: [email protected]

Kontakt/Contact


Sprache/Language


Donnerstag/Thursday, 07.10.2010Forensik

Dr. Annette Schwenzer, Promega GmbH

Aktuelle Entwicklungen in der Forensik

Dr. Carsten Proff, Insitut für Blutgruppenforschung LGC GmbH

International Commission on Missing Persons:

An overview its objectives, capabilities, and the use of genetic databases

Dr. Tom Parsons, Director of Forensic Sciences, ICMP

Die Zuverlässigkeit forensischer DNA-Tests, Maßnahmen zur Vermeidung von Fehlern

Dr. Hildegard Haas, Genedia AG

Forensische Genetik – Dem Täter auf der Spur

Herr Dr. rer. nat. Carsten Hohoff, Institut für Forensische Genetik GmbH, Münster

Biobanken/Biobanks

Dr. Annette Schwenzer, Promega GmbH

Aufbau einer Biobank am Beispiel von Life&Brain

Dr. Per Hoffmann, Institut für HumangenetikForschungszentrum Life&Brain Universitätsklinikum Bonn

Alma in Silico – an euregional platform to sharing and coordinating competences, services,

training and cooperative research in systems biology

Dr. Heinrich Delbrück, Institut für Molekulare Biotechnologie an der RWTH Aachen

13:24–13:42Deutsch

Moderation:

13:06–13:24Deutsch

12:48–13:06Deutsch

12:18–12:48Deutsch

12:00–12:18Deutsch

Moderation:

13:42–14:00English

35

Enabling Technologies

Life Science Spotlight 2010 – Forensics/Biobanks

Halle/hall 9, Stand/booth G61, (platform Innovation Forum)

07.10.2010, 12:00–14:00 Uhr/hrs









Kontakt/Contact


Sprache/Language


34

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Versette is here to get you there.

Moving science forward

Visit our free lunch seminar! Incorporating Versatility and Scalability in Laboratory Sample Preparation Procedures

Wednesday 6 October 2010, 12:15 – 14:00 h

Room Hamburg, Convention Centre, Ground Floor

Learn how the new Thermo Scientific Versette automated liquid handler

can take your sample preparation to the next level of efficiency.

Speaker: Kiara W. Biagioni, Product Manager Automation Liquid Handling

To register please send an email to: [email protected]

Visit our booth in hall 9 / G51!

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[email protected]:otliamenad

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Session 2

Dr. Claudia Ulbrich, ulbrich&partner Unternehmensberatung

Erfahrungsbericht: Erfolgreiche Kapitalgewinnung

Report on successful recovery of funding

Dr. Marcus Furch, Chief Executive Officer, Rodos BioTarget GmbH

Unternehmenspräsentationen

(6 Unternehmen, 10 Min. Vortrag + 5 Min. Fragen)

Company presentations

(6 Companies à 10 min. presentation + 5 min. for questions)

Get together15:00–16:00

13:30–15:00

13:15–13:30

Moderation:

37


2nd Bio@venture Conference 2010

Convention Center (CC), Saal/room Heidelberg

05.10.2010, 09:30–15:00 Uhr/hrs

Die Bio@venture Conference 2010 ist der Ort, an dem Life Science-Ideen auf neues Kapital treffen! Sie bietet, nunbereits zum zweiten mal, die Plattform für Unternehmer, Ihre innovativen Ideen vor Investoren und potenziellenBeteiligungskapitalgebern zu präsentieren. Die Kurzvorträge von ausgewählten Unternehmen vermitteln den erstenEindruck für spätere direkte Verhandlungen.

The Bio@venture Conference 2010 is the venue where life science ideas correlate with new capital! For the secondtime the conference offers a platform to entrepreneurs to present their innovative ideas to investors. The short presentations of selected enterprises give a first impression of the idea and are followed by individual negotiationslater on.

Investitions- und Förderbank Niedersachsen – NBank, Deutsche Messe AG, BioRegioN,Enterprise Europe Network NiedersachsenGünther-Wagner-Allee 12–16D–30177 Hannover

Deutsch oder Englisch / German or English

Teilnahmegebühr + gesetzl. MwSt. und Messeeintritskarte. Unternehmen: 300,00 EUR /Investoren: kostenfrei. Anmeldung erforderlich unter www.bioatventure.deParticipation fee (+ V.A.T.) and entrance ticket to fair. Companies: 300,00 EUR / Investors: free ofcharge. Registration required online at www.bioatventure.de

Melanie AlbrechtTelefon: 0511-30031-368Fax: 0511-30031-11368E-mail: [email protected]

Dienstag/Tuesday, 05.10.2010Registrierung der Teilnehmer

Admission and registration

Begrüßung

Welcome note

Stephan Ph. Kühne, Mitglied des Vorstands, Deutsche Messe AG

Grußwort

Welcome note

Dr. Oliver Liersch, Niedersächsischer Staatssekretär für Wirtschaft, Arbeit und Verkehr

Session 1

Ansgar Rudolph, BioRegioN

Branchenüberblick Biotechnologie 2010

Overview Biotechnologie 2010

Dr. Susanne Wosch, Senior Industry Specialist Health Sciences, Ernst & Young GmbH

Unternehmenspräsentationen

(6 Unternehmen, 10 Min. Vortrag + 5 Min. Fragen)

Company presentations

(6 companies à 10 min. presentation + 5 min. for questions)

Mittagspause

Lunch break

12:15–13:15

10:45–12:15

10:20–10:45

Moderation:

10:10–10:20

10:00–10:10

09:30–10:00

Kontakt/Contact


Sprache/Language


36


Gen Drug Discovery Theatre

Halle/hall 9, Stand/booth B23

05.10.2010–06.10.2010, 14:00–17:00 Uhr/hrs

GEN will sponsor a “Discovery Theater” at BIOTECHNICA, which will feature a series of 45-minute panel discussi-ons each led by a moderator. The panels will be drawn from academia and industry. The focus will be on the deve-lopment and application of novel drug discovery tools, techniques, methodologies, strategies, and products.

Since large pharma companies have seen their own new drug pipelines dry up, technology transfer of promisingnewly discovered compounds from academia and small biotech companies to international drug firms will be a keytopic of discussion. A wide range of scientific and technical issues will be explored, including those involvingADME/TOX, assay development, biomarkers, gene expression, microarrays, nanotechnology, PCR, RNAi, next-gene-ration sequencing, cell based assays, lead discovery and validation, and many more.

Genetic Engineering News140 Huguenot StreetUSA–10801 New Rochelle

Englisch/English


John SterlingTelefon: +1 914/740-2100Fax: +1 914/740-2201E-mail: [email protected]

Dienstag/Tuesday, 05.10.2010Dipl.-Kfm. Axel Koch MBA, Managing Director of ElexoPharm GmbH

From Academia to Big Pharma - Key Success Factors in the Technology Transfer Process

Prof. Dr. Markus Meyer, CEO of Focus IP GmbH; Dr. Michael Huhn, European Patent Attorney andHead of the working group “Technology Transfer” of the Licensing Executive Society LESGermany; Dr. Jörg Knäblein, Head Technology Scouting Bayer Schering Pharma

Advances in molecular diagnostics and its impact on the drug industry

Stephem Little, Ph.D., Vice President Personalized Healthcare, Qiagen

Simultaneous Confirmation of Protein Sequence and Quantitation of Post-translational

Modifications

Dr. Patrick Boyce, Waters

Using IPA to Compare Pathways, Biological Processes Impacted by Celebrex and Vioxx:

Case Study in Mechanism of Toxicity Hypothesis Generation

Adam S. Corner, PhD. Senior Scientist, Europe, Ingenuity Systems

Mittwoch/Wednesday, 06.10.2010TGF-ß / TGF-ß2 and its role in aggressive cancer diseases

Dr. Hubert Heinrichs, Chief Medical Officer at Antisense Pharma

TGF-ß / TGF-ß2 and its role in aggressive cancer diseases

Prof. Peter ten Dijke, professor of molecular cell biology at Leiden University, The Netherlands

Therapies targeting TGF-ß - an overview

Dr. Piotr Jachimzcak, Member of the American Association for Cancer Research (AACR) and theEuropean Neurooncology Organisation (EANO)

14:30–15:00

14:00–14:30

Moderation:

16:15–17:00

15:30–16:15

14:45–15:30

14:00–14:45

Moderation:

Kontakt/Contact


Sprache/Language


38

Special Events

Inhibition of TGF-ß2 in high-grade glioma patients – clinical results of the international

Phase IIb study (Publ. in press)

PD Dr. Peter Hau, Attending, Section Leader of the Department NeuroOncology (associate profes-sor), University of Regensburg

Pressure Cycling Technology (PCT): A Novel, Enabling Platform Revolutionizing Biomarker

Discovery

Nathan Lawrence, Ph.D., Vice President of Marketing, Pressure BioSciences, Inc.

Bead Based Protein Arrays

Dr. Janet Krege, New Technology Evaluation, R&D, Merck KGaA, Darmstadt

BMBF Projektforum Biotechnologie / BMBF Project Forum Biotechnology

Halle/hall 9, Stand/booth C25

05.10.2010–07.10.2010

Im Rahmen des Projektforums werden die vom Bundesministerium für Bildung und Forschung (BMBF) gefördertenProjekte vorgestellt, die im Laufe des Jahres 2009 abgeschlossen wurden. Gegenstand aller präsentierten Projekte istdie Biotechnologie mit ihren unterschiedlichen Aspekten, von der molekularen Diagnostik über das Wirkstoff-Designund Ernährungsaspekte bis hin zur Pflanzenzucht und zu Industriellen Biotechnologie. Wie auch in den vergangenenJahren werden die Vorträge in der Halle 9 auf dem Messegelände in einer allen zugänglichen Arena gehalten.

The Project Forum will be holding a number of presentations on projects that were funded by the Federal Ministryfor Education and Research (BMBF) and which ended in 2009. The subject of the presented projects will be biotech-nology, in all its various aspects, spanning from molecular diagnostics, drug design and aspects of nutrition to cropbreeding and industrial biotechnology. As in previous years the event will take place in hall 9 in a lecture arena thatwill be open to all.

Bundesministerium für Bildung und ForschungHannoversche Str. 28-30D–10115 Berlin

Vom BMBF mit der Organisation beauftragt ist:BIOCOM Projektmanagment GmbHBrunnenstr. 12813355 Berlin

Deutsch/German

Dr. Boris MannhardtTelefon: 030/26492161E-mail: [email protected]

Dienstag/Tuesday, 05.10.2010, 09:40–17:30 Uhr/hrsAnalyse zellulärer Komponenten

Generation von Mutationen mit Hilfe von neuartigen Ansätzen

Dr. Thomas Floss, Helmholtz Zentrum München

Ansatz zur Analyse einer Signaltransduktions-Domäne

Dr. Hermann Heumann, Silantes GmbH; München

Analyse des Membranproteoms von Bakterien

PD Dr. Ansgar Poetsch, Ruhr-Universität Bochum

Analyse dynamischer Prozesse in lebenden Systemen

Dr. Marius Ueffing, Klinikum rechts der Isar der Technischen Universität München10:10–10:20

10:00–10:10

09:50–10:00

09:40–09:50

Kontakt/Contact

Sprache/Language


16:15–17:00

15:30–16:15

15:00–15:30

39

Special Events

Identifizierung von Biomarkern für urologische Erkrankungen

Dr. Eric Schiffer, Mosaiques Diagnostics GmbH, Hannover

Prädiktive Biomarkerprofile für die individuelle Tumortherapie

Prof. Dr. Heinz-Herbert Fiebig, Oncotest GmbH, Freiburg

Molekulare Diagnostik

Detektion von Frühstadien des Plattenepithelkarzinoms in der Mundhöhle

Dr. Stephan Schwarz-Furlan, Institut für Pathologie Kaufbeuren

Empfindliche Diagnostik für die Alzheimer-Krankheit

Constantin Odefey, ATTO-LAB GmbH, Lübeck

Verbesserte Diagnostik der Basedow-Krankheit

Prof. Dr. Ulrich Loos, KreLo GmbH, Ulm

Neuer Test zur molekularen Diagnose der rheumatoiden Arthritis

Dr. Thomas Flad, PANATecs GmbH, Tübingen

Genotyp-spezifischer HCV-Diagnostikchip

Dr. Stefan Barth, Fraunhofer-Institut für Molekularbiologie und Angewandte Ökologie,Schmallenberg

Neuartiges medizinisches Gerät für die Dickdarm-Tumordiagnostik

Dr. Stefan Schulz, Sondervermögen Großforschung beim KIT, Eggenstein-Leopoldshafen

Immundiagnostische Kits zur Verbesserung von Latex-Produkten

Dr. Steffen Rupp, Fraunhofer-Institut für Grenzflächen- und Bioverfahrenstechnik, Stuttgart

Zielstrukturen für die Medikamentenentwicklung

Charakterisierung von Multiple Sklerose-assoziierten Antigenen

Dr. Alexander Zaigler, Ganymed Pharmaceuticals AG, Mainz

Neuer Ansatz zur Behandlung von Autoimmunkrankheiten der Schilddrüse

Dr. Wolfgang Rudy, MicroMol GmbH, Karlsruhe

Validierung von TrkB als Tumortarget


Transketolase – ein neues Target für die Therapie von Tumorerkrankungen

Dr. Peter Schubert, R-Biopharm AG, Darmstadt

Identifikation allergener Substanzen

Dr. Thomas Joos, EDI Experimentelle & Diagnostische Immunologie GmbH, Reutlingen

Tests zur Prüfung auf Entwicklungsneurotoxizität

Dr. Andrea Seiler, Bundesinstitut für Risikobewertung, Berlin

Mittwoch/Wednesday, 06.10.2010, 09:40–17:30 Uhr/hrsEntwicklung neuer Wirkstoffe

Identifizierung neuer Wirkstoffe gegen Darmkrebs


Naturstoffe aus Algen zum Schutz vor mutagenen Schäden

Prof. Dr. Otto Pulz, IGV Institut für Gertreideverarbeitung GmbH, Bergholz-Rehbrücke

Neuartige antidiabetische Wirkstoffe aus Pflanzen

Dr. Lutz Müller-Kuhrt, Analyticon Discovery GmbH, Potsdam

14:40–14:50

10:00–10:10

09:50–10:00

09:40–09:50

17:20–17:30

17:10–17:20

17:00–17:10

16:50–17:00

16:40–16:50

16:30–16:40

16:10–16:20

16:00–16:10

15:50–16:00

15:40–15:50

15:30–15:40

15:20–15:30

15:10–15:20

14:50–15:00

41

Special Events

Messung dynamischer zellulärer Ereignisse

Dr. Marc Bickle, Max-Planck-Institut für Molekulare Zellbiologie und Genetik, Dresden

Struktur und Zusammensetzung von Amyloidfibrillen

Dr. Marcus Fändrich, Max-Planck-Forschungsstelle für Enzymologie und Proteinfaltung, Halle (Saale)

Zellfreie Synthese von Membran-Proteinen

Prof. Dr. Richard Wagner, Universität Osnabrück

Genom- und Proteomanalyse

Neue Werkzeuge für die funktionelle Genom- und Proteomforschung

Dr. Wilfried Weigel, Scienion AG, Dortmund

Lipoproteinanalytik mittels NMR-Spektroskopie

Christiane Proll, LipoFIT Analytic GmbH, Regensburg

Neuartige Massenspektrometrie zur bioanalytischen Charakterisierung von Gewebe

Prof. Dr. Bernhard Spengler, Justus-Liebig-Universität Gießen

Entwicklung von Themen-spezifischen Protein-Biochips

Dr. Angelika Lüking, Protagen AG, Dortmund

Neues Verfahren zur absoluten Quantifizierung von Proteinen

Markus Fischer, Entelechon GmbH, Regensburg

Nested On-Chip PCR

Dr. Patric Zeltz, BF-BIOlabs Schneider Zeltz, Denzlingen

3-D-Mikrodissektion biologischer Objekte

Dr. Winfriede Weschke, Institut für Pflanzengenetik und Kulturpflanzenforschung, Gatersleben

Wissenschaftskommunikation und Bionik

Tribologie im Dünensand – Skink, Boa und Käferlarve als Vorbild für die

Reibungsminderung

Prof. Dr. Ingo Rechenberg, Technische Universität Berlin

eLearning als Ausbildungsmodul zur Qualifikation von Studierenden

Prof. Dr. Gerhard Heldmaier, Philipps-Universität Marburg

Biotechnologie zum Anfassen

Alexandra Schautz, PHAENO gGmbH, Wolfsburg

Odysseum Köln: Biotechnologie und Lebenswissensschaften

Julia Schropp, SK-Stiftung CSC – Cologne Science Center, Köln

Sondervortrag

Start-Up Finanzierung mit dem High-Tech Gründerfonds

Marco Winzer, High-Tech Gründerfonds Management GmbH, Bonn

Biomarker für die Medizin

Analysesystem für die markergestützte intraoperative Tumordiagnostik

Dr. Rainer Hintsche, AJ eBiochip GmbH, Itzehoe

Neuartige molekulare Tumor-Prognostik

Dr. Fritz Grunert, Genovac GmbH, Freiburg

Neue diagnostische Marker für die Zöliakie

Dr. Jörg-M. Hollidt, In Vent GmbH, Henningsdorf14:30–14:40

14:20–14:30

14:10–14:20

13:50–14:00

12:50–13:00

12:40–12:50

12:30–12:40

12:20–12:30

12:00–12:10

11:50–12:00

11:40–11:50

11:30–11:40

11:20–11:30

11:10–11:20

11:00–11:10

10:40–10:50

10:30–10:40

10:20–10:30

40

Special Events

BMBF Projektforum Biotechnologie BMBF Projektforum Biotechnologie

Neue Enzyme zur Herstellung von biobasierten Produkten

Dr. Ulrich Fehrenbacher, Fraunhofer-Institut für Chemische Technologie, Pfinztal

Produktion neuartiger Enzyme für industrielle Anwendungen

Dr. Oliver Kensch, Direvo Industrial Biotechnology GmbH, Köln

Neue Hydrolasen und Oxidoreduktasen für industrielle Anwendungen

Dr. Thomas Greiner-Stöffele, c-LEcta GmbH, Leipzig

Therapie einer seltenen Stoffwechselerkrankung: Von der Grundlagenforschung direkt ans

Krankenbett

Prof. Dr. Guenter Schwarz, Universität zu Köln

Ernährung und Gesundheit

Krankheitsprävention durch Ernährung

PD Dr. Diana Rubin, Christian-Albrechts-Universität zu Kiel

Einfluss probiotischer Mikroorganismen auf Entzündungen des Magen-Darm-Trakts

Dr. Gabriele Hoermannsperger, Technische Universität München

Prüfung und Optimierung der gesundheitsfördernden Eigenschaften von Kaffee

Dr. Gerhard Bytof, TCHIBO GmbH, Hamburg

Wirkung von unterschiedlichen Stärkegehalten in Kartoffeln auf den Organismus

Dr. Joachim Spranger, Deutsches Institut für Ernährungsforschung, Bergholz-Rehbrücke

Funktionelle Lebensmittel

Verbesserung der Nahrungsmittelqualität und der menschlichen Gesundheit

Dr. Guido Jach, Phytowelt Green Technologies GmbH, Nettettal

Funktionelle Lebensmittel für die Gefäßgesundheit

Dr. Sarah Egert, Universität Bonn

Funktionelle Eigenschaften von Lebensmitteln durch präbiotische Ballaststoffe

Dr. Michael Glei, Friedrich-Schiller-Universität, Jena

Pflanzenöle und Omega-3 Fettsäuren zur Prävention von Stoffwechselkrankheiten

Dr. Petra Wiedmer, Deutsches Institut für Ernährungsforschung, Bergholz-Rehbrücke

Procyanidine – Vom Verständnis der Wirkung zur Entwicklung funktioneller Lebensmittel

Prof. Dr. Sabine E. Kulling, Universität Potsdam

Donnerstag/Thursday, 07.10.2010, 09:40–15:50 Uhr/hrsRegenerative Medizin

Faktoren für die Geweberegenerierung

Prof. Dr. Elly Tanaka, Max-Planck-Institut für Molekulare Zellbiologie und Genetik, Dresden

Wachstumsfaktoren für die klinische Anwendung

Dr. Rolf Bechtold, BIOPHARM GmbH, Eppelheim

Biofunktionale Oberflächen für zelltherapeutische Verfahren

Andrea Schnell, Gambro Dialysatoren GmbH, Hechingen

Adhäsionsbarrieren

Prof. Dr. Burkhard Schlosshauer, NMI Naturwissenschaftliches und Medizinisches Institut an derUniversität Tübingen

Zellwanderung während der neuronalen Regeneration

Dr. Reinhard Köster, Helmholtz Zentrum München

15:00–15:10

14:50–15:00

10:20–10:30

10:10–10:20

10:00–10:10

09:50–10:00

09:40–09:50

17:10–17:20

17:00–17:10

16:50–17:00

16:40–16:50

16:30–16:40

16:10–16:20

16:00–16:10

15:50–16:00

15:40–15:50

15:20–15:30

15:10–15:20

43

Special Events

Wirkstoffe für eine neuartige Behandlung bakterieller Infektionen

Dr. Lutz Müller-Kuhrt, Analyticon Discovery GmbH, Potsdam

Neuartige Wirkstoffe zur Behandlung der Zöliakie

Dr. Ralf Pasternak, Zedira GmbH, Darmstadt

Entwicklung eines neuen anti-Entzündungstherapeutikums

Dr. Ulrich Becker, Labtec GmbH, Langenfeld

Molekulare Medizin

Vorhersage der Aufnahme und Verteilung von Wirkstoffen mittels Computersimulation

Dr. Norbert Siedow, Fraunhofer-Institut für Techno- und Wirtschaftsmathematik, Kaiserslautern

Impfstoff gegen schwer therapierbare Infektionskrankheiten

Dr. Jochen Probst, CureVac GmbH, Tübingen

Impfstoff zur Behandlung von Asthma und anderen allergischen Erkrankungen

Dr. Kerstin Lux, MediGene AG, Martinsried

Impfstoff zur Behandlung von Glioblastomen

Dr. Oliver Schoor, Immatics Biotechnologies GmbH, Tübingen

Photodynamische Therapie der Sepsis

Prof. Dr. Volker Albrecht, biolitec AG, Jena

Produktionsverfahren für Wirkstoffe

In vitro Produktion von humanen monoklonalen Antikörpern

Dr. Frank Breitling, Deutsches Krebsforschungszentrum Heidelberg

Neue Herstellverfahren für die Immunzelltherapie

Dr. Christoph Giese, ProBioGen AG, Berlin

Neuartiges Expressionssystem für pharmazeutische Glykoproteine

Dr. Hans Baumeister, Glycotope GmbH, Berlin

Neues kostengünstiges Expressionssystem zur Produktion von Biopharmazeutika

Dr. Marcus Hartmann, Cilian AG, Münster

Produktion neuartiger Biopharmazeutika im Moos

Dr. Christian Stemmer, greenovation Biotech GmbH, Freiburg

Technologie zur Beschleunigung der biopharmazeutischen Produktentwicklung

Dr. Dagmar Wirth, Helmholtz Zentrum für Infektionsforschung, Braunschweig

Übertragung der koaxialen Airjet Droplet-Technologie in Einzelkapseltechnologie

PD Dr. Thomas Forst, IKFE Institut für klinische Forschung und Entwicklung GmbH, Mainz

Sondervortrag

Start-Up Finanzierung mit dem High-Tech Gründerfonds

Dr. Mehran Rafigh, High-Tech Gründerfonds Management GmbH, Bonn

Industrielle Biotechnologie

Analyse des Stoffwechsels mikrobieller Aminosäureproduzenten

Prof. Dr. Ralf Takors, Universität Stuttgart

Biotechnologische Herstellung von Zimtsäure

Dr. Arne Peters, E-NEMA Gesellschaft für Biotechnologie und biologischen Pflanzenschutz mbH,Raisdorf

Neue Systeme zum Auffinden und Verbessern industriell bedeutsamer Biokatalysatoren

Dr. Patrick Lorenz, B.R.A.I.N. AG, Zwingenberg

10:10–10:20

10:20–10:30

14:40–14:50

14:30–14:40

14:20–14:30

14:00–14:10

12:50–13:00

12:40–12:50

12:30–12:40

12:20–12:30

12:10–12:20

12:00–12:10

11:50–12:00

11:30–11:40

11:20–11:30

11:10–11:20

11:00–11:10

10:50–11:00

10:30–10:40

42

Special Events

BMBF Projektforum Biotechnologie BMBF Projektforum Biotechnologie

Neue Methoden für die Pflanzen- und Tierzucht

Produktion eines antimikrobiellen Proteins in Pflanzen

PD Dr. Michael Kleine, Planton GmbH, Kiel

Molecular Farming

Dr. Nicole Raven, RWTH Aachen

Molecular Farming in geschlossenen Anbausystemen

Dr. Frank Gilmer, Forschungszentrum Jülich

Plantibodies und klassische Antikörper gegen ein Vogelvirus

Dr. Dierk Rebeski, Lohmann Animal Health GmbH & Co. KG, Cuxhaven

BIOTECHNICA PARTNERING

Halle/hall 9, Stand/booth C65

05.10.2010 – 07.10.2010

BIOTECHNICA PARTNERING ist Ihr Weg um One-To-One-Meetings mit Wissenschaftlern, Forschungsinstituten und Firmen zu vereinbaren. Sie treffen, wen Sie wollen, um zu diskutieren, was Sie möchten – alles um den best-möglichen Partner für die Verwirklichung Ihrer Ideen und zur Weiterentwicklung Ihrer Geschäfte zu finden.Das System partneringONE® der EBD Group unterstützt Sie dabei effektiv Meetings mit den richtigenGesprächspartnern vereinbaren zu können, um den maximalen Nutzen für Ihre wissenschaftlichen Projekte oderInnovationen zu generieren. Der Partnering-Prozess startet bereits vor der Veranstaltung. Registrieren Sie sich jetzt und erstellen Sie Ihr Profil,um für den Start des BIOTECHNICA PARTNERINGS in wenigen Wochen bereit zu sein.Auf Ihrem Partnering-Account können Sie sich jederzeit einloggen, um Ihre Meeting-Agenda zu planen undGesprächstermine zu vereinbaren. Es werden nur Meetings in Ihrer Agenda aufgenommen, die von beiden Seitenbestätigt sind. Wenn Sie zur BIOTECHNICA anreisen, wissen Sie also bereits, mit wem Sie sich wann und wo tref-fen werden.Die One-to-one Meetings dauern jeweils 30 Minuten und finden in den Meeting-Boxen in der Halle 9 oder auf denStänden der Aussteller statt. So können Sie Ihre Partnering-Meetings mit anderen Aktivitäten auf der BIOTECHNICAkombinieren. Ein Help Desk an der Partnering-Area unterstützt Sie in allen Fragen.

BIOTECHNICA PARTNERING is your route to arranging one-to-one meetings with scientists, research institutes andcompanies. You meet who you want, to discuss what you want.EBD Group’s partneringONE® system ensures that you can efficiently arrange to meet the right people for yourspecific collaboration aims, whatever scientific project or innovation you are working on. The partnering process starts well before the event. Registration is available and enables you to profile your organization to be ready for the launch of partnering by mid of August 2010.Once partnering is launched, you can log in anytime to plan your own agenda and pre-arrange one-to-one meetings.Only meetings that have been accepted by both parties will be scheduled. Arrive at BIOTECHNICA knowing whoyou are meeting with.One-to-one meetings last 30 minutes. They will take place in dedicated meeting booths in Hall 9 or at exhibitionbooths, making it easy to combine your meetings with other activities. A Partnering Help Desk – also located in Hall9 – will assist you with any questions on site.

Deutsche Messe AGin cooperation with: EBD Group, Zürich

Englisch/English (Online Platform)

Anmeldung erforderlich unter www.biotechnica.de/partnering_d

Teilnahmegebühr (zzgl. ges. MwSt.):99,00 EUR (Besucher Industrie) – inkl. Messeeintrittskarte59,00 EUR (Besucher Akademia) – inkl. Messeeintrittskarte199,00 EUR (Aussteller)59,00 EUR (Mitaussteller Ländergemeinschaftsstand)


Sprache/Language


15:30–15:40

15:20–15:30

15:10–15:20

15:40–15:50

45

Special Events

Unterstützung der Regeneration der Leber bei akutem Leberversagen

Dr. Martin Schenk, Eberhard-Karls-Universität Tübingen

Zellsuspension zur Behandlung von Strikturen der Harnröhre

Dr. Gerhard Feil, Eberhard-Karls-Universität Tübingen

Tissue Engineering

Follikuläre Stammzellen für die Rekonstruktion menschlicher Haut

Christina Fieber, euroderm GmbH, Leipzig

Bioartifizieller Gefäßersatz

Monika Schulze, JOTEC GmbH, Hechingen

Herstellung einer Herzklappe durch Tissue Engineering

Dr. Michael Harder, CorLife GbR, Hannover

Regeneration der Bandscheibe durch Tissue-Engineering

Karin Benz, NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen

Neuro-Tissue Engineering von Büngner Bändern

Prof. Dr. Burkhard Schlosshauer, NMI Naturwissenschaftliches und Medizinisches Institut an derUniversität Tübingen

Interaktive Neuroprothese für das Gehör

Prof. Dr. Frank W. Ohl, Leibniz-Institut für Neurobiologie, Magdeburg

Innovative biomedizinische Verfahren

Neue präklinische Werkzeuge für die Therapieoptimierung bei Darmkrebs

Prof. Dr. André Rosenthal, Signature Diagnostics AG, Potsdam

Retina Implantat: Optimierte Stimulation degenerierter Netzhäute

Dr. Walter-G. Wrobel, Retina Implant AG, Reutlingen

Nanopolymere Kontrastmittel für die Photoakustik

Dr. Robert Lemor, Fraunhofer-Institut für Biomedizinische Technik, St. Ingbert

Toxische Wirkung von Stoffen nach Direktexposition von Lungenzellen

Dr. Jan Knebel, Fraunhofer-Institut für Toxikologie und Experimentelle Medizin, Hannover

Entwicklung einer Biohybridlunge

Dr. Andreas Maurer, Novalung GmbH, Oberstenfeld

Neuregulin-vermittelte Neuroprotektion

Prof. Dr. André Schrattenholz, ProteoSys AG, Mainz

Optimierung von Nutzpflanzen

Development of yellow-seeded, low sinapine oilseed rape

Dr. Felix Dreyer, Norddeutsche Pflanzenzucht Hans-Georg Lembke KG, Holtsee

Markergestützte Rückkreuzungsanalyse bei Mais

Dr. Martin Ganal, TraitGenetics GmbH, Gatersleben

Analyse von Blühgenen der Zuckerrübe

Dr. Axel Schechert, Strube Research GmbH & Co. KG, Söllingen

Selektionsmethoden zur Züchtung Krankheits-resistenter Zuckerrüben

Dr. Markus Wolf, Strube Research GmbH & Co. KG, Söllingen

Charakterisierung von Stoffwechselprozessen in Kartoffelknollen

Prof. Dr. Peter Geigenberger, Ludwig-Maximilians-Universität München

10:30–10:40

10:40–10:50

14:50–15:00

14:40–14:50

14:30–14:40

14:20–14:30

14:10–14:20

13:00–13:10

12:50–13:00

12:40–12:50

12:30–12:40

12:20–12:30

12:10–12:20

11:50–12:00

11:40–11:50

11:30–11:40

11:20–11:30

11:10–11:20

11:00–11:10

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Special Events

BMBF Projektforum Biotechnologie

Lateinamerika Verein e.V.in cooperation with: Global GmbH (NGlobal)

German-English-Spanish (simultaneous translation)

Besucher der Biotechnica haben die Möglichkeit, an den Veranstaltungen des Lateinamerika-Tageszum reduzierten LAV-Mitgliedspreis teilzunehmen.

Teilnahmegebühr (inkl. 19% MwSt.):

Wirtschaftstag Mexiko (06.10.)105,00 EUR (LAV-Mitgliederpreis)

Konferenz: Technologiekooperationen – Lateinamerika und Deutschland (07.10.)155,00 EUR (LAV-Mitgliederpreis)

Visitors of the Biotechnica can participate in the events of the Latin American Day 2010 at thereduced LAV member rate.

Participation fee (incl. 19% VAT):

Business Meeting: Focus on Mexico (06.10.)105,00 EUR (LAV-member-price)

Conference “Cooperation in technology – Latin America and Germany” (07.10.) 155,00 EUR (LAV-member-price)

Imke SchröderTelefon: +49 40 413 43 13Fax: +49 40 45 79 60E-mail: [email protected]


Sprache/Language


Kontakt/Contact

47

Special Events

Online registration required at www.biotechnica.de/partnering_e

Participation fee (+V.A.T.):99,00 EUR (Visitors Industry) – incl. entrance ticket to the fair59,00 EUR (Visitors Academia) – incl. entrance ticket to the fair199,00 EUR (Exhibitors)59,00 EUR (Exhibitors of a country joint stand)

Janine WendtTelefon: +49 511/89 32179E-mail: [email protected]

Lateinamerika-Tag 2010

P37/Nord/LB forum

06.10.2010 – 07.10.2010

Seit 61 Jahren veranstaltet der Lateinamerika Verein jährlich das Schlüsselereignis in den deutsch-lateinamerika-nischen Wirtschaftsbeziehungen, den Lateinamerika-Tag. Die zweitägige Veranstaltung gliedert sich in einenWirtschaftstag und einen Konferenztag. Den feierlichen Abschluss bildet ein Galadiner, zu dem traditionell ein latein-amerikanischer Präsident eingeladen wird. In 2010 sind die thematischen Schwerpunkte des Lateinamerika-Tages Mexiko und am zweiten Tag dieTechnologiekooperation zwischen Deutschland und Lateinamerika. Der Wirtschaftstag Mexiko ist auch als Beitragdes LAV zum Bicentenario zu verstehen und wird den aktuellen Stand und die zukünftigen Trends der Deutsch-Mexikanischen Wirtschaftsbeziehungen beleuchten. Der anschließende Konferenztag ist den Kooperationen undPartnerschaften zwischen Deutschland und den lateinamerikanischen Ländern beim Technologietransfer gewidmet. Referenten aus Politik und Wirtschaft werden zu Themen der Automobilindustrie, Infrastruktur, Energie undAerospace sowie Forschung, Entwicklung, Innovation und Standortwahl sprechen und diskutieren.

Die diesjährige Veranstaltung wird in Kooperation mit der Niedersachsen Global GmbH (NGlobal) ausgerichtet und stehtunter der Schirmherrschaft des Niedersächsischen Ministerpräsidenten David McAllister. Wir freuen uns, als Ehrengastzum Galadiner die Präsidentin der Republik Argentinien, I.E. Dr. Cristina Fernández de Kirchner, zu begrüßen.

For 61 years the Latin American Day has been the annual highlight of German-Latin American business relations.Hold by the Latin American Business Association (LAV), the event is divided into a Business Meeting focussed on aparticular country, and a Conference. The closing event is a Gala Dinner whose traditional guest of honour is thepresident of a Latin American country. The central topics of the 2010 Latin American Day will be Mexico and Technology Cooperation between Germanyand Latin America. The Business Meeting is also understood as a contribution to the Bicentenario, presenting thecurrent situation and the future prospects of German-Mexican business relations. The Conference deals with diffe-rent aspects of the technology transfer between Latin America and Germany. High-ranking representatives of the political and the private sector will present and discuss the automotive industry,infrastructure, energy and aerospace as well as research, development, innovation and choice of industrial location. This years’s conference is organized in cooperation with Niedersachsen Global GmbH (NGlobal) and will take placeunder the patronage of the Prime Minister of Lower Saxony, David McAllister. We are looking forward to welcomethe President of Argentina, H.E. Dr. Cristina Fernández de Kirchner as Guest of Honour at our Gala Dinner.

Kontakt/Contact

46

Special Events

Bioenergoinformation of a living organizm – „DINO96“ – versatile use

mgr inz. Jan StojHalle/hall 9 – Forum 2, Stand/booth G61

The inwestigations and obserwations demonstrate the activity of DINO-96 in differents of bio-medicne, biomarkers,extremalactivity-emergency, express diagnostic with DINO-96 method, biocosmetology, antybioterroryzm, ecology,agriculture and veterinary, military and sport and.......H1N1?

Veranstalter/Organizer: DINO-96

We target disease

Dr. Andre HoekemaHalle/hall 9 – Forum 2, Stand/booth G61

Galapagos applies its target discovery engine in human cells to discover and develop novel mode-of-action drugsacross a wide range of diseases. Based on this approach, Galapagos signed 8 strategic pharma alliances and deliveredmultiple clinical and pre-clinical drug candidates, thereby building a leading, profitable European biotech company.

Veranstalter/Organizer: Galapagos NV

Apeiron Biologics: privately financed, private success

Dr. Hans LoibnerHalle/hall 9 – Forum 2, Stand/booth G61

Apeiron Biologics is engaged in focused R&D of innovative therapeutic approaches with clinical and commercialvalue. A novel enzyme therapy was developed up to end of Phase I and licensed to GlaxoSmithKline in early 2010.Additional projects are in the area immunologic/biologic therapy of cancer.

Veranstalter/Organizer: APEIRON Biologics AG

Biotechnik / Bioengineering

Industrielle Biotechnologie: Ein Markt für Forschung und Entwicklung

Dr. Manfred KircherHalle/hall 9 – Forum 2, Stand/booth G61

Es wird erwartet, dass bis 2020 mehr als 20% aller Chemieprodukte biobasiert hergestellt werden. Damit gewinntdie industrielle Biotechnologie auf zwei Schlüsselmärkten wesentlich an Bedeutung: 1.bei der Herstellung nach-wachsender Kohlenstoffquellen und 2. bei deren Transformation in werthaltige Chemieprodukte. Der Vortrag disku-tiert den F&E Markt.

Veranstalter/Organizer: CLIB2021 – Cluster Industrielle Biotechnologie e.V.

Targeted transgene integration in a CHO-S hotspot for the fast and reproducible production

of high protein titers

M. Sc., Peter SteinhardtHalle/hall 9 – Forum 1, Stand/booth B49

The desired characteristics of a mammalian cell expression system include the ability to quickly and reproduciblygenerate stable clones producing high titers of recombinant proteins and mAbs. This can be achieved using meganu-clease-driven targeted integration, to stably express proteins from selected transcriptionally active genomic region.

Veranstalter/Organizer: Cellectis bioresearch

14:15–14:40English

11:30–11:55Deutsch

16:15–16:40English

15:45–16:10English

14:15–14:40English

49


Innovation Forum

Halle/hall 9, Forum 1: Stand B49, Forum 2: Stand G61

05.10.2010 – 07.10.2010

Anlässlich der BIOTECHNICA 2010 präsentieren sich auf dem Innovation Forum in 15 bis 25-minütigen Vorträgenzahlreiche Unternehmen aus allen Sparten der Biotech-Branche und informieren über ihre innovativen Leistungenund Produkte. Dabei spiegeln sich die Ausstellungsschwerpunkte von der Biotechnik und -informatik überDienstleistungen und Equipment bis hin zu den Anwendungsbereichen Pharmazie/ Medizin, Ernährung sowieLandwirtschaft und Umwelt in den Fokusthemen wider.Das Innovation Forum findet auf insgesamt 2 offen gestalteten Vortragsplattformen direkt im Ausstellungsbereichender Halle 9 statt. Für Besucher der BIOTECHNICA ist die Teilnahme kostenfrei. Dadurch haben Sie die Möglichkeit,sich einfach und unkompliziert über Innovationen aus erster Hand zu informieren, mit den Referenten in den Dialogzu treten und interessante Kontakte zu knüpfen.

The Innovation Forum at BIOTECHNICA 2010 features a rich series of 15 to 25-minute lectures and demonstrationsby companies from every conceivable sector of the biotech industry keen on presenting their latest technologies,products, achievements, service offerings, bioinformatics solutions and equipment as well as intriguing biotechapplications in pharmaceuticals, medicine, nutrition, agriculture and environmental protection.The presentations will be held at two locations in hall 9, right on the exhibition floor. Attendance is FREE for all BIO-TECHNICA visitors, who will find the Innovation Forum to be an optimal setting in which to pick up valuable know-how, discover the latest breakthroughs and engage in face-to-face dialogue with fellow professionals.

Deutsche Messe AG


Teilnahme kostenfrei in Verbindung mit einer MesseeintrittskarteParticipation free of charge to BIOTECHNICA ticket holders

Jens BürgerTelefon: +49 511 89-33574Fax: +49 511 89-30998E-mail: [email protected]

Dienstag/Tuesday, 05.10.2010

Medizin, Pharmazie / Medical and pharmaceutical applications

Diskonnektoren und Konnektoren für sichere sterile Interaktionen

Mona KellerHalle/hall 9 – Forum 2, Stand/booth G61

Pall geht mit der Familie der Kleenpak Sterile Disconnectors neue Wege, Einwegsysteme in nicht-klassifizierterArbeitsumgebung validiert steril voneinander zu trennen. In Verbindung mit der Familie der Kleenpak SterileConnectors ergibt sich ein breites Portfolio für GMP-konformes Fluidhandling in Einwegsystemen.

Veranstalter/Organizer: Pall GmbH

Micro-24 Microbioreactor: “High-throughput” bioreactors redefining cell line optimization

and process development

Tiffany D Rau, PhDHalle/hall 9 – Forum 2, Stand/booth G61

The Pall Micro-24 Microbioreactor is a disposable 24 well system with individual pH, DO, and temperature control.The “high-throughput” system allows to maximize the likelihood of obtaining a “winning” cell line and scalable pro-cess early in development. Microbial as well as mammalian applications of the system will be discussed.

Veranstalter/Organizer: Pall GmbH

11:00–11:25English

10:30–10:55Deutsch

Kontakt/Contact


Sprache/Language


48


BX3 – built by your needs

Die neuen aufrechten Mikroskopsysteme von Olympus

Dr. Jan BarghaanHalle/hall 9 – Forum 2, Stand/booth G61

Mit den Systemen der neuen aufrechten Mikroskopfamilie BX3 präsentiert Olympus einzigartige und innovativeLösungen für die Anforderungen der modernen Arbeitswelt, sowohl im Klinik- als auch im Forschungsalltag.

Veranstalter/Organizer: Olympus Deutschland GmbH

HSG-IMIT Lab-on-a-Chip Design and Foundry Service

Dr. Felix von StettenHalle/hall 9 – Forum 1, Stand/booth B49

The portfolio of the HSG-IMIT of Lab-on-a-Chip Design and Foundry Service comprises design, prototyping andtesting of customized Lab-on-a-Chip applications. A special expertise is the upgrade of conventional laboratory devices such as Real-Time PCR thermocycler to realize inbuilt microfluidic process automation.Ref.: www.loac-hsg-imit.de

Veranstalter/Organizer: HSG-IMIT

3D Fluoreszenz Imaging einfach gemacht

Dr. Hubert BauchHalle/hall 9 – Forum 2, Stand/booth G61

Mit dem VivaTome stellt Carl Zeiss eine neue Technologie für das 3D Imaging lebender Proben vor. Über die Technikder „Aperture Correlation“ lassen sich scharfe und kontrastreiche Bilder von dicken Proben erzeugen, die mit kon-ventionellen Fluoreszenztechniken überstrahlt aussehen.

Veranstalter/Organizer: Carl Zeiss Microlmaging GmbH

sam5 biosensor – A new solution for simple and robust label-free biomolecular interaction

analyses in biotech and academia

Dr. Thomas GronewoldHalle/hall 9 – Forum 2, Stand/booth G61

sam5 is a new, easy to use biosensor for label-free real-time biomolecular analyses. It enables high quality kineticinteraction detection, determination of affinity constants, binding specifity and analyte concentration. Superior tocommon systems it allows to detect protein conformational changes in membranes and vesicles due to bindingevents.

Veranstalter/Organizer: SAW instruments GmbH

BlueInOne – the smallest gas analysis for bioprocesses

Dr. Holger MüllerHalle/hall 9 – Forum 1, Stand/booth B49

BlueInOne is the smallest gas analyzer worldwide with the best long term stability. It includes simultaneous com-pensation of pressure, humidity and temperature for the measurement of gases such as O2 and CO2. Due to thisnew analyzer bioprocesses of any kind can be controlled online without the need of additional calculations.

Veranstalter/Organizer: BlueSens gas sensor GmbH

Chancen und Möglichkeiten – real-time PCR

Holger DensowHalle/hall 9 – Forum 1, Stand/booth B49

Im dem Vortrag werden die Grundlagen der PCR und real-time PCR beschrieben und die beiden neuen real-timePCR Thermocycler TOptical und qTOWER vorgestellt. Darüber hinaus werden methodische Neuentwicklungenanschaulich erläutert und es wird auf Perspektiven der real-time PCR eingegangen.

Veranstalter/Organizer: Analytik Jena AG

11:30–11:55Deutsch

12:00–12:15English

15:45–16:10Deutsch

15:15–15:40English

14:45–15:10English

14:15–14:40Deutsch

51


A novel animal component free surface for growth of stem cells and other fastidious cells

Dr. Y. Cindy NeeleyHalle/hall 9 – Forum 2, Stand/booth G61

The new Thermo Scientific Nunclon Vita is an energy-treated polystyrene surface free of animal components. It enablesculture of human stem cells without matrix or feeder layers. Cells are grown directly on the surface in conditionedmedia containing ROCK-inhibitor, and can be sustained for more than ten passages without signs of differentiation.

Veranstalter/Organizer: Thermo Fisher Scientific Nunc

Equipment

evapeosTM: The new generation of evaporators for Life Sciences

Dr. Fabrice Gascons ViladomatHalle/hall 9 – Forum 2, Stand/booth G61

Downstream processing of bioproducts is a major issue in biomanufacturing because they are highly diluted inwater. evapeosTM allows a fast concentration at room temperature and atmospheric pressure, leading to very lowthermal and shear stress on the products.

Veranstalter/Organizer: Ederna

Robotic Liquid Handling

Kajsa PetterssonHalle/hall 9 – Forum 1, Stand/booth B49

Xiril’s series of liquid handling robotic workstations provides the precision, robustness, cost efficiency and ease ofuse to cope with laboratories´ needs. With smart technology and user-friendly software customers can easily trans-form their applications onto these flexible, open designed robotic workstations.

Veranstalter/Organizer: GC biotech B.V.

Bioinformatik, Service / Bioinformatics, Services

All year exposure on BIOTECHNICA Homepage TV

drs Rob ChömpffHalle/hall 9 – Forum 1, Stand/booth B49

BIOTECHNICA Homepage TV with exhibitor videos proofed to be the most popular HOTSPOT (3 videos/300 Euro)

– All year long every week the Biotechnica Homepage attracts minimal 5000 visits /week resulting 16000 visitors/year

– Exhibitor commercials draw up to 4500 views/commercial (and leads)– New technology! Your webcommercial is ready in ONE day (from 450 Euro) including turnkey text coaching

Presentation time:10.30 – 10.55 / 11.30 – 11.55 / 14.45 – 15.10 / 16:15 – 16.40

Veranstalter/Organizer: Webvertising Studios


Equipment

Metallisch dichtende Aseptik-Rohrverbindung ConnectS®

Harry JostHalle/hall 9 – Forum 2, Stand/booth G61

ConnectS® ist die weltweit erste und einzige hygienische Rohrverbindung, die ohne Elastomere auskommt. DieVerbindung ist so konstruiert,daß alle relevanten Anforderungen in Bezug auf Hygiene – Sicherheit erfüllt werden.

Veranstalter/Organizer: NEUMO GmbH + Co. KG

15:15–15:40English

14:45–15:10English

11:00–11:25Deutsch

10:30–10:55English

15:15–15:40English

50


53


Biotechnik / Bioengineering

Multiplexed biomolecular interactions monitoring using Surface Plasmon Resonance

imaging (SPRi)

Dr. Elodie LY-MORINHalle/hall 9 – Forum 1, Stand/booth B49

Surface Plasmon Resonance imaging (SPRi) takes bimolecular interaction analysis a step further. This label-free andsensitive technique allows up to serveral hundreds interactions to be monitored simutneously in real-time.Applications on cell capture and ligand fishing by SPRi-mass spectrometry will be presented.

Veranstalter/Organizer: HORIBA Jobin Yvon GmbH

A novel bioreactor for tissue reconstruction in vitro

Dr. Antje FuhrmannHalle/hall 9 – Forum 1, Stand/booth B49

Dedifferentiation of primary cells and associated loss of functionality when cultivated in vitro are still the major limi-tations in tissue engineering. A promising approach to abolish these limitations is the use of bioreactors enabling anin vivo like cultivation. In this study a novel bioreactor system suitable for load bearing tissue is discussed.

Veranstalter/Organizer: Greiner Bio-One GmbH

German-Russian Forum

Industrial Biotechnology in Russia

German-Russian cooperation in biotechnology: outlook and perspectives

Dr. Christian Patermann, Former Director EU-CommissionHalle/hall 9 – Forum 1, Stand/booth B49

Industrial biotechnology is one of the most promising areas of future economic success: ranging from new bioba-sed materials to the production of new enzymers. Russia with its huge reservoir of biomass and Germany with itsportfolios in life sciences can strongly complement their activities on the road to a knowledge-based bio-Economy.

Veranstalter/Organizer: Deutsche Messe AG

Applications in Design of Experiments in optimal recombinant protein production

with the multibiorector system BIOSTAT Qplus

Prof. Dr.-Ing. Reiner Luttmann, Hochschule für Angewandte Wissenschaften (HAW) HamburgHalle/hall 9 – Forum 2

Optimisation of recombinant protein processes, fully automated DoE-Design of Experiments, Modde®, BIOSTAT®Qplus and Bplus multi-fermenter system, production of potential Malaria vaccines with Pichia pastoris, maximizingsoluble proteins in Escherichia coli, at-line RP-HPLC measurement of target protein concentration and product quality.

Veranstalter/Organizer: Sartorius Stedim Biotech GmbH

Upcyte technology allows extended proliferation of primary cell cultures

Dr. Joris Braspenning, Medicyte GmbHHalle/hall 9 – Forum 2, Stand/booth G61

Medicyte has developed a new technology to allow the proliferation of differentiated primary cells without inducingpermanent immortalization, uncontrolled cell growth, or loss of phenotype. The technology involves a viral genetransfer system to introduce a combination of genes that induce & maintain cell proliferation until cells reach conflu-ence.

Veranstalter/Organizer: LGC Standards GmbH

16:45–17:10English

15:45–16:10English

14:40–15:00English

11:30–11:55English

11:00–11:25English

Raman Spektroskopie – Eine Technologie zum Gewinn neuer Informationen für LifeScience

Anwendungen

Dr Johanna NeumayerHalle/hall 9 – Forum 1, Stand/booth B49

Raman Spektroskopie eröffnet spezifische Informationen auf molekularer Ebene (z.B. von Peptiden, Proteinen, DNA,etc) und ist sensitiv auf Veränderungen innerhalb von Biomolekülen. Diese “label-freie” Technologie kann bildgebend(Raman Imaging) und räumlich hochauflösend bis hin in den subzellularen Bereich eingesetzt werden.

Veranstalter/Organizer: HORIBA Jobin Yvon GmbH

Medizin, Pharmazie / Medical and pharmaceutical applications

A low cost molecular diagnostics platform for infectious diseases

Rob Jenison, Chief Technology OfficerHalle/hall 9 – Forum 2, Stand/booth G61

The Portrait molecular diagnostics platform utilizes isothermal amplification and eye visible chip-based detection toprovide low cost results. Data will be shown on the first clinical application for detecting Staphylococcus speciesand the oxacillin resistance marker mecA from positive blood cultures.

Veranstalter/Organizer: Great Basin Scientific



Overview on the Russian Industrial Biotechnology Sector

Prof. Raif VasilovHalle/hall 9 – Forum 1, Stand/booth B49

Main characteristics of the current state of the biotech industry in Russia: Market volume ~ $ 1.6 billion; Growth rate ~ 10-12%; Market saturation

Veranstalter/Organizer: Deutsche Messe AGVERANSTALTER/ORGANIZER: DEUTSCHE MESSE AG

SPS – Stabilization and Protection of Biologics during Storage and Sterilization

Michael SchollHalle/hall 9 – Forum 2, Stand/booth G61

LEUKOCARE’s technologies allow to extend shelf life of biologics in dehydrated state and to retain functionalityduring sterilization by gamma-, beta-radiation or ethylene oxide. LEUKOCARE’s technologies enable the design of anew range of products in the fields of biologic-device combination products, biopharmaceuticals and diagnostics.

Veranstalter/Organizer: Leukocare AG

The riboxx® HTP-RNA-Synthesis: A fast, easy and cost-effective method dedicated to

siRNA-screens

Dr. med. habil. Jacques RohayemHalle/hall 9 – Forum 2, Stand/booth G61

A new technology based on the properties of an RNA polymerase to synthesize siRNA in high throughput has beendeveloped. Synthesis, purification and analysis are very fast, allowing tremendous saving in time and cost of goodsfor setting up RNAi-screens.

Veranstalter/Organizer: Riboxx GmbH

16:15–16:40English

15:15–15:40English

14:20–14:40English

10:30–10:55English

16:15–16:40Deutsch

52


Bioinformatik, Service / Bioinformatics, Services

Data analysis in an instant – a simpler and faster way to explore large data sets

Ann Holmberg, M. Sc.Halle/hall 9 – Forum 1, Stand/booth B49

Qlucore Omics Explorer (OE) is the software for intuitive bioinformatics, developed with the researcher in mind. Itgives instant response when exploring your data. It is an interactive analysis and visualization tool that helps theuser to very quickly identify groups, structures, variable networks and discriminating variables in large data sets.

Veranstalter/Organizer: Qlucore AB

Identification of Genes, Pathways and Processes

Affected by Cancer Kinase Inhibitors Using IPA and Ingenuity Answers

Adam S. Corner, PhDHalle/hall 9 – Forum 2, Stand/booth G61

Ingenuity Answers and IPA allow scientists to ask and answer detailed questions about drugs, targets and diseasespowered by the Ingenuity Pathways Knowledge Base. This seminar will illustrate a workflow centered aroundBreast Cancer kinases, their drugs, downstream targets and inferred off target effects.

Veranstalter/Organizer: Ingenuity Systems, Inc.

Genevestigator – how are your genes expressed across thousands of experimental

conditions, diseases and tumors?

Dr. Philip ZimmermannHalle/hall 9 – Forum 1, Stand/booth B49

Genevestigator is a revolutionary tool to easily and quickly find out which conditions affect the expression of genesof interest. By summarizing expression values from more than 50’000 high quality microarrays, user-friendly toolshelp to understand the function of genes or to find genes that are related to selected conditions (biomarker genes).

Veranstalter/Organizer: Nebion AG



German-Russian Cooperation Network Biotechnology

Dr. Gabriele Gorzka, East-West-Science Center, University of KasselHalle/hall 9 – Forum 1, Stand/booth B49

Biotechnology is one of the fastest and strongest growing industrial sectors of the world economy. The German-Russian Cooperation Network Biotechnology supports collaboration between German and Russian research institu-tes and industry.

Veranstalter/Organizer: Deutsche Messe AG

Use of pre-barcoded media for paperless Environmental Monitoring

Dr. Ulrich Eikmanns, Head of Product Management, heipha Dr. Müller GmbH / Mr. MichaelDesiderio, Global Director, Informatics, Lonza Cologne AGHalle/hall 9 – Forum 1, Stand/booth B49

Discussion on the current challenges in Quality Control as they relate to managing samples and information.Problems and inefficiencies with paper-based systems for QC will be contrasted with strategies for automation,including the use of pre-barcoded media and the critical features necessary for it to play a central role in the paper-less lab.

Veranstalter/Organizer: heipha Dr. Müller GmbH / Lonza Cologne AG

16:45–17:10English

14:00–14:20English

10:30–10:55English

10:00–10:25English

10:00–10:25English

54


Verleihung des BIOTECHNICA Studienpreises 2010 /

Award of the BIOTECHNICA Study Price 2010

Halle/hall 9, Stand/booth E41

06.10.2010, 11:00–12:00 Uhr/hrs

Der Verband Biologie, Biowissenschaften und Biomedizin – VBIO zeichnet herausragende experimentelle Abschluss-arbeiten unterschiedlicher Disziplinen der Biowissenschaften aus. Der von Roche unterstützte und mit insgesamtvon 5.000 Euro dotierte Preis wird am 6. Oktober um 11:00 Uhr an die drei Preisträger vergeben.

Outstanding experimental degree theses from all bioscience areas will be awarded by the VBIO. The prize is sponsored by Roche.

VBIO e.V.Corneliusstr. 12D–80469 München

Deutsch/German


Dr. Carsten RollerTelefon: +49 89/26024573Fax: +49 89/26019729E-mail: [email protected]

jobvector-Karrierestand / jobvector Career BoothHalle/hall 9, Stand/booth B5305.10.2010–07.10.2010, 09:00–18:00 Uhr/hrs

Jobwall, Information und persönliche Beratung

Als zentrale Anlaufstelle für Stellensuchende dient der jobvector-Karrierestand: Jobwall, Informationen und persön-liche Beratung. An allen drei Messetagen können Bewerber an der jobvector-Jobwall aktuellste Stellenausschrei-bungen von BIOTECHNICA-Ausstellern und von jobvector finden, die über das Online-Angebot hinausgehen.

Bewerber erfahren alles über die neuesten Berufsaussichten, Trends und Perspektiven rund um den Arbeitsmarkt.

Jobwall, Information and Personal AdviceAs a central contact point for job seekers the jobvector-Career Booth offers: Jobwall, information and advice. On allthree event days applicants can find the most current job ads from companies exhibiting at BIOTECHNICA and fromjobvector, outnumbering vacancies offered online.

Applicants can take advantage of several options to gather information and find out all there is to know about thetopics career choice, application and employment.

jobvectorKölner Landstr. 40D–40591 Düsseldorf



Dr. Martina SribarTelefon: +49 211 301384-08Fax: +49 211 301384-18E-mail: [email protected]

Kontakt/Contact

Kontakt/Contact


Sprache/Language



Sprache/Language


55



Donnerstag/Thursday, 07.10.2010

Christoph Pietsch, jobvector

Begrüßung

jobvector-the Science career center

Spectaris Light Alliance – Zukunft als Lichtingenieur – Karrierechancen in der Photonik

Birgit Ladwig, Leiterin Fachverband Photonik + Präzisionstechnik im Hightech-VerbandSPECTARIS, Spectaris Light Alliance

Kelly Scientific Resources – Ihr starker Partner in der Personalvermittlung

Simone Flachmann, Kelly Scientific Resources

Bird Engineering BV – How to apply for beginners

Brenda Berenman, Bird Engineering BV

Pause / break

Thermo Fisher Scientific – World Leader in Serving Science

Karl-Gerhard Hoppmann, Thermo Fisher Scientific

nemensis ag – The human factor

Christian Schneeberger, nemensis ag

Olympus Europa Holding GmbH- Olympus als Arbeitgeber inkl. Erfahrungsbericht eines

Trainees Vertrieb

Heino Plöger und Dr. Moritz Paehler, Olympus Europa Holding GmbH

Pause/ break

BASF – The Chemical Company

Dr. Sarah Ulmschneider, BASF SE

Abbott GmbH & Co. KG – Abbott eine Leidenschaft fürs Leben

Joachim Walk, Abbott GmbH & Co. KG

Miltenyi Biotec GmbH – Über die Kunst kleinste Dinge zu trennen

Prof. Dr. Uwe Heinlein, Miltenyi Biotec GmbH

Pause / break

KWS Saat AG – Wer Möglichkeiten sucht, denkt Orange

Nadine Bautz, KWS Saat AG

Life Technologies GmbH – Perspektiven bei Life Technologies

Dr. Arne Schierau, Life Technologies GmbH

BioBusiness Summer School 2011

Josée Lenoir, BioBusiness summer school

LSR-Life Science Research – Der Vertrieb als Arbeitgeber

Dr. Wolfgang Kronemeyer, Qiagen und Günter Wagner, Thermo Fisher Scientific, LSR-Life ScienceResearch

jobvector-the Science career center – Jobsuche in der Praxis

Tom Wiegand, jobvector-the Science career center16:40–17:00Deutsch

16:20–16:40Deutsch

10:50–11:10English

10:30–10:50Deutsch

10:05–10:30Deutsch

10:00–10:05Deutsch

Moderation:

Kontakt/Contact

16:00–16:20English

15:40–16:00Deutsch

15:20–15:40Deutsch

14:40–15:20Deutsch

14:20–14:40Deutsch

14:00–14:20Deutsch

13:35–14:00Deutsch

12:35–13:35Deutsch

12:15–12:35Deutsch

11:55–12:15Deutsch

11:30–11:55Deutsch

11:10–11:30Deutsch

57


jobvector-Check / jobvector-Checking Service

Convention Center (CC), Raum/room 214, 216/

07.10.2010, 09:00–18:00 Uhr/hrs

Bewerbungsmappencheck

Am jobvector career day bietet jobvector gemeinsam mit einer Personalagentur eine fachspezifische DurchsichtIhrer Unterlagen an.In kleinen Gruppen werden die Stärken und Schwächen der mitgebrachten Bewerbungen analysiert. Die intensiveAnalyse und Beratung wird in Kleingruppen in separaten, ruhigen Räumlichkeiten durchgeführt.

Application Portfolio Checking ServiceAt the jobvector career day, jobvector and a HR agency offer an expert check of your documents.In small groups the strong and weak points of your application that you bring along, will be analyzed. The intensecheck and consultation takes place in separate and quiet rooms.



Teilnahme kostenfrei in Verbindung mit einer Messeeintrittskarte. Die Anzahl der Teilnehmer istbeschränkt; bitte melden Sie sich frühzeitig an unter www.jobvector.de/hannoverParticipation free of charge to BIOTECHNICA ticket holders. The number of participants is limited;please register early on www.jobvector.de/en/hannover


jobvector-Forum

Halle/hall 9, Stand/booth B49, (platform INNOVATION FORUM)/

(platform INNOVATION FORUM)

07.10.2010, 10:00–17:00 Uhr/hrs

Vorträge zu Beruf und Karriere im wissenschaftlich-technischen Bereich

Es erwartet Sie ein spannendes und unterhaltsames Vortragsprogramm rund um die Themen Berufswahl,Bewerbung und Karriere. Top Arbeitgeber stellen sich vor und sprechen über individuelle Einstiegsmöglichkeiten undüber Karriereperspektiven im Unternehmen.

Talks on Job Profiles and Career Opportunities in the fields of sciences and technologyYou can expect an exciting and comprehensive programme of talks surrounding the topics choice of profession,application and career. Top companies introduce their company as well as their career options.





Sprache/Language


Sprache/Language


Kontakt/Contact


56


jobvector-Networking

Halle/hall 9, Stand/booth B53

07.10.2010, 09:00–18:00 Uhr/hrs

Im Gespräch mit Personalverantwortlichen

Am Stand von jobvector kommen Sie direkt mit Personalverantwortlichen beteiligter Firmen ins Gespräch.Sie können sich persönlich vorstellen, einen ersten Eindruck des Unternehmens gewinnen und sich über Ihre individuellen Karriereperspektiven informieren.Das Begleitheft zum career day präsentiert Ihnen alle teilnehmenden Firmen. Es ist vor dem Event als Downloaderhältlich und wird auch auf der Veranstaltung verteilt.

Talking to HR ManagersAt our booth you can talk directly to HR-managers of participating companies and have the chance to introduceyourself in person, gain a first impression and get some information about individual career prospects.Our accompanying booklet for the jobvector career day will present you all participating companies. It is available asdownload before the fair and will also be distributed at the fair.





Kontakt/Contact


Sprache/Language


58


PROGRAM & EVENT GUIDES

2nd Annual

Pages B2-B10

PEGSProtein & Antibody Engineering Summit

Second Annual

Pages P11-P20

MOLECULAR DIAGNOSTICSEUROPE

Pages M21-M29

www.Bio-ITWorldExpoEurope.com B-1

Organized & Managed by:

Cambridge Healthtech Institute

250 First Avenue, Suite 300 Needham, MA 02494 USAPhone: +1.781.972.5400 Fax: +1 781.972.5425Email: [email protected]

Europe’s No.1 Event in Biotechnology and

Life Sciences

IT Infrastructure & Informatics: Data Storage, Analysis and Visualization

NGS Data Management: Sequencing Systems, Storage, and Analysis

IT Infrastructure & Informatics: Collaborative Software, Standards & Web Technologies

Data Integration & Knowledge Management

5-6 October 6-7 October

Premier Sponsors:

Corporate Sponsors:

S-2

1st

fl oo

r

grou

nd fl

oor

2nd Annual


Second Annual MOLECULAR DIAGNOSTICSEUROPE


Bio-IT World Europe PEGS Europe Molecular Diagnostics Europe

Conference Registration: Front of Room 1

MONDAY, 4 OCTOBER COURSES

Next-Gen Sequencing Data

Room 13 Protein Aggregation Room 16 Room Berlin

Biomedical Data Fusion Room Dresden Biomedical Data Fusion Room Dresden

Cloud Computing Room 13Room BerlinVisualization of Omics

DataRoom 14

Coffee & Refreshment Breaks: Outside Session Room

Exhibit & Poster Viewing Hall 9 (CHI Pavillion which is across from the Catering area)

BIOTECHNICA Opening Reception & Award Ceremony Located in Room 1

TUESDAY, 5 OCTOBER SESSIONS

Track 1 Room 13/14 Track 1 Room 1A Track 1 Room Dresden

Track 2 Room 15/16 Track 2 Room 1B Track 2 Room Berlin

Breakout Discussion Groups

Rooms 11 & 12 Breakout Discussion Groups

Rear of Rooms 1A & 1B


Room Bonn



CHI Reception Located in the Foyer

WEDNESDAY, 6 OCTOBER SESSIONS

Track 1 Room 13/14 Track 1 & 3 Room 1A Track 1 & 2 Room Bonn

Track 2 Room Bonn Track 2 & 4 Room 1B Track 3 Room Dresden

Track 3 Room 13/14

Track 4 Room 15/16



BIOTECHNICA Night! Traditional Bavarian Beer Hall, dinner reception, live band playing popular music from U.S. Location: Münchner Hall

THURSDAY, 7 OCTOBER SESSIONS


Track 4 Room 15/16 Track 4 Room 1B



Quick Reference to Locations for Sessions, Exhibits & Posters, and Receptions

About Cambridge Healthtech Institute - Your Life Science Network Founded in 1992, Cambridge Health-

tech Institute (CHI) strives to develop

quality information sources that provide

valuable new insights and competing points of

view while offering balanced coverage of the lat-

est developments in the life sciences industry.

Basic research related to commercial implica-

tions is covered, with heavy emphasis placed on

end-user insights into new products and technol-

ogy as well as coverage of the strategy behind the

business.

Cambridge Healthtech Institute (CHI) is the

preeminent life science network for leading

researchers and business experts from top phar-

maceutical, biotech, and academic organizations.

CHI’s integrated portfolio of products and ser-

vices includes Cambridge Healthtech Institute

Conferences, the Pharmaceutical Strategy Series,

Insight Pharma Reports, Cambridge Marketing

Consultants, Cambridge Meeting Planners, and

Cambridge Healthtech’s Media Group, which

includes numerous eNewsletters, Bio-IT World

magazine, as well as Lead Generation Programs.

For a comprehensive listing and detailed

information, visit the following web sites:

Conferences: www.healthtech.com

www.barnettinternational.com

www.chacorporate.com

www.insightpharmareports.com

http://proservices.healthtech.com


www.chimediagroup.com

[Exclusive BIoITWorld Conferene & Expo Europe

Follow us on #BioIT102010 Sponsor:

ABOUT

Bio-IT World (www.bio-itworld.com), the fl agship publication

of Cambridge Healthtech Institute (CHI), is the leading source of

news on technology and strategic innovation in drug discovery, de-

velopment and clinical trials. Bio-IT World’s focus is increasingly

one that explores the tools and results of “predictive biology” as

the industry adapts to the new world of “personalized medicine.”

Bio-IT World has won 34 national and regional awards, more than

any other magazine covering the life sciences industry. Bio-IT

World, part of Cambridge Healthtech Media Group—a division

of CHI—also produces a comprehensive, continually updated

website, topic-specifi c briefi ngs, white papers, webcasts, podcasts,

lished in 2001, the magazine is based in Needham, Massachusetts

in the U.S.

www.Bio-ITWorldExpoEurope.com B-2 Please note: Video and/or audio recording of

any kind is prohibited onsite at all CHI events.

Bio-IT World Europe CONFERENCE-AT-A-GLANCEMonday, 4 October

8:20-9:30 Pre-Conference Short Course Registration (separate registration required) Convention Center in front of Room 1

10:00-13:30 Short Course 1 Making Sense of Next-Gen Sequencing Data Location: Room 13

14:00-17:00 Short Course 2 Creating Synergy – Introduction to Biomedical Data Fusion Location: Room Dresden

14:00-17:00 Short Course 3 Cloud Computing for Life Sciences Location: Room 13

14:00-17:00 Short Course 4 Visualization of Large-Scale Biological Data Location: Room 14

16:00-18:30 Conference Registration Convention Center in front of Room 1

18:30 Biotechnica Opening and European Award Ceremony plus Reception Room 1

Tuesday, 5 October

Track 1: IT Infrastructure & Informatics: Data Storage, Analysis & Visualization Location: Room 13/14

Track 2: NGS Data Management: Sequencing Systems, Storage & Analysis Location: Room 15/16


9:30-10:35 Large Scale Data Storage, Retrieval and Accessibility –Leading EU Centers Room 13/14

Informatics: Meeting the Challenge of Turning NGS Data into Knowledge Room 15/16

10:35-11:00 Coffee Break Sponsored by Outside Session Room

11:00-12:30 Large Scale Data Storage, Retrieval and Accessibility – Leading EU Centerss Room 13/14

Informatics: Meeting the Challenge of Turning Ngs Data into Knowledge Room 15/16

12:30-14:20 Exhibit & Poster Viewing. Lunch for purchase at Catering Area in Exhibit Hall 9. Visit the Cambridge Healthtech Institute (CHI) Pavilion across from Catering. iPod® raffl e daily at 13:30 at CHI’s Pavilion. To enter, drop off business card at CHI’s Registration Desk or exhibit booth.

14:30-15:35 Storage: Solutions for Massive Sequencing Data Managements Room 13/14

Storage: Solutions for Massive Sequencing Data Management Room 15/16

15:35-16:00 Refreshment Break Outside Session Room

16:00-18:15 Storage: Solutions for Massive Sequencing Data Management Room 13/14

Storage: Solutions for Massive Sequencing Data Management Room 15/16

18:15-19:15 Interactive Breakout Discussion Groups Room 11/12 Interactive Breakout Discussion Groups Room 11/12

19:15-21:00 Cambridge Healthtech Institute (CHI) Networking Dinner Reception Sponsored by Location: Foyer

Wednesday, 6 October

9:30-10:35 Imaging Solutions in Drug R&D: Data Analysis, Implementation, Standards and Quality Room 13/14

Sequencing Data: Provides a Promising Tool for Molecular Diagnostics Room Bonn


11:00-12:30 Keynote Presentations - IT & Informatics in Support of Drug DiscoveryRoom 13/14

Sequencing Data: Provides a Promising Tool for Molecular Diagnostics Room Bonn


13:45 Close of Conference

Track 3: IT Infrastructure & Informatics: Collaborative Software, Standards & Web Technologies Location: Room 13/14

Track 4: Data Integration & Knowledge Management Location: Room 15/16


14:00-15:35 Data Integration and Collaboration Room Bonn Data Integration and Collaboration Room Bonn


16:00-17:30 Case Studies of Open Collaborations and Open Source Software Room 13/14

Knowledge Management for Target Discovery Room 15/16

18:30-21:00 BIOTECHNICA Night! Traditional Bavarian Beer Hall, dinner reception, live band playing popular music from U.S. Location: Münchner Hall

Thursday, 7 October

9:30-10:35 Implementing Standards to Reach Process Effi ciency and Interoperability – Metadata and Beyond Room 13/14

Translational Informatics: Knowledge Fertilization BetweenBench and Bedside Room 15/16

10:35-11:00 Coffee Break Outside Session Room

11:00-12:30 Ontologies and State-of-the-Art Web Technologies: Bring the Knowledge to the User Room 13/14

Ontologies and State-of-the-Art Web Technologies: Bring theKnowledge to the User Room 15/16



Ontologies and State-of-the-Art Web Technologies: Bring the Knowledge to the User Room 15/16



Ontologies and State-of-the-Art Web Technologies: Bring the Knowledge to the User Room 15/16



TUESDAY, 5 OCTOBER (Afternoon Sessions)

IT Infrastructure & Informatics:Data Storage, Analysis and Visualization

Location: Room 13/14

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STORAGE: SOLUTIONS FOR MASSIVE SEQUENCING DATA MANAGEMENT

14:30 Chairperson’s Remarks14:35 Featured Presentation:

Sequencing Data Storage Chris Dagdigian, Founding Partner &

Director, Technology, BioTeam, Inc.

15:05 Experiences from the European Bioinformatics Institute’s Data Resources, Storage, and Management

Guy Cochrane, Ph.D., European Nucleotide Archive Team

Leader, Bioinformatics Institute

16:00 How Scale-out Requirements in Life Sciences are Making Obsolete RAID, LUNs, Volumes and the Rest of the Traditional Storage Model

Rob Anderson, Director, Technology & Business

Development, EMEA

16:30 How to Overcome the 100 Miles Between Petabases and Petabytes

Jürgen Eils, Bioinformatics Database Group Leader, German

Cancer Research Center

17:00 Enhanced Scalabilty, Large Data Volumes Management, Integrated Analysis, and NGS Informatics Support in a Medical Setting

Andrew Stubbs, Ph.D., Assistant Professor, Department of

Bioinformatics, Erasmus Medical Center

17:30 The First Success Stories after the Swedish Buildup of Computational Power and Large-Scale Storage for Gene-Sequence Data

Ingela Nystrom, Ph.D., Director, UPPMAX, Center for Image

Analysis, Uppsala University

Sponsored by

Sponsored by

STORAGE: SOLUTIONS FOR MASSIVE SEQUENCING DATA MANAGEMENT

14:30 Chairperson’s Remarks14:35 Featured Presentation:

Sequencing Data Storage Chris Dagdigian, Founding Partner &

Director, Technology, BioTeam, Inc.

15:05 Experiences from the European Bioinformatics Institute’s Data Resources, Storage, and Management

Guy Cochrane, Ph.D., European Nucleotide Archive Team

Leader, Bioinformatics Institute

15:35 Refreshment Break

16:00 How Scale-out Requirements in Life Sciences are Making Obsolete RAID, LUNs, Volumes and the Rest of the Traditional Storage Model

Rob Anderson, Director, Technology & Business

Development, EMEA

16:30 How to Overcome the 100 Miles Between Petabases and Petabytes

Jürgen Eils, Bioinformatics Database Group Leader, German

Cancer Research Center

17:00 Enhanced Scalabilty, Large Data Volumes Management, Integrated Analysis, and NGS Informatics Support in a Medical Setting

Andrew Stubbs, Ph.D., Assistant Professor, Department of

Bioinformatics, Erasmus Medical Center

17:30 The First Success Stories after the Swedish Buildup of Computational Power and Large-Scale Storage for Gene-Sequence Data

Ingela Nystrom, Ph.D., Director, UPPMAX, Center for Image

Analysis, Uppsala University

18:15 Interactive Breakout Discussion Groups Location: Room 11/121. Repositories of Metagenomic Data and Tools for Academic and

Commercial UsersModerator: Oleg Reva, Ph.D., Senior Lecturer, Biochemistry,

University of Pretoria

2. Storage of Omic Data - The Cloud & BeyondModerator: Chris Dagdigian, Founding Partner & Director of

Technology, BioTeam, Inc.

3. Web ServicesModerator: Christian Hauck, Ph.D., Knowledge Management &

Competitive Intelligence, Novartis Pharma AG

4. Analyzing and Storing Gene Sequence DataModerator: Ingela Nystrom, Ph.D., Director, UPPMAX, Center for

Image Analysis, Uppsala University

5. Semantic Web and OntologiesModerator: Martin Gollery, Senior Bioinformatics Scientist, Tahoe

Informatics

19:15 CHI Networking Dinner Reception Location: Foyer

Sponsored by

Sponsored by

Enjoy an evening with your colleagues and discover the world of German cuisine.

Sponsored by


TUESDAY, 5 OCTOBER (Morning Sessions)



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INFORMATICS: MEETING THE CHALLENGE OF TURNING NGS DATA INTO KNOWLEDGE

9:30 Chairperson’s Remarks9:35 Into the Unknown: Expression Profi ling without

Genome Sequence Information by Next-Generation Sequencing

Fabian Birzele, Ph.D., Genomics, Boehringer Ingelheim Pharma,

GmbH & Co. KG

10:05 Iterative Read Mapping and Assembly Allows the Use of a More Distant Reference in Metagenome Assembly

Bas E. Dutilh, Ph.D., Centre for Molecular and Biomolecular

Informatics, Nijmegen Center for Molecular Life Sciences,

Radboud University Nijmegen Medical Center

11:00 Utilizing Next-Generation Sequencing to Analyze the Complex Genome of Barley

Burkhard Steuernagel, Department of Cytogenetics and

Genome Analysis, Leibniz Institute of Plant Genetics and Crop

Plant Research (IPK)

11:30 Fully Automated Genome Annotation with Deep RNA Sequencing

Gunnar Rätsch, Ph.D., Group Leader, Friedrich Miescher

Laboratory, Max Planck Society

12:00 Next Gen Data Management for Next Gen Life SciencesRoberto Fabbretti, Ph.D., IT

Manager, Swiss Institute of

Bionformatics

12:15 Avadis NGS – Next-Gen Sequencing Analysis for the Rest of Us

Thon de Boer, Ph.D., Director, Product

Management, Software, Strand Scientifi c

Intelligence, Inc.

Sponsored by

Sponsored by

www.Bio-ITWorldExpoEurope.com 65

9:00 Conference Registration and Morning Coffee

LARGE SCALE DATA STORAGE, RETRIEVAL AND ACCESSIBILITY – LEADING EU CENTERS

9:30 Chairperson’s Remarks Derek Burke, Director, International

Marketing, Panasas

9:35 Next-Generation Sequencing Data: Next-Generation Management Problems

Guy Coates, Ph.D., Informatics System Group, The Wellcome

Trust Sanger

10:05 Keeping Pace—Scalable IT Infrastructures to Support Data Intensive Science

Rupert Lueck, Ph.D., Head, IT Services, EMBL Heidelberg

10:35 Coffee Break Sponsored by

11:00 Omics Data - Serving Sequencing at the National Level

Francois Artiguenave, Ph.D., Head, Bioinformatics Laboratory,

Genoscope

11:30 Speaker to be Announced

12:00 Data Management Challenges in Translational Collaborative Research and Clinical Care at Erasmus MC

Bert Eussen, Clinical Genetics, Erasmus MC

Peter Walgemoed, Director, Carelliance

12:30-14:20 Dedicated Exhibit & Poster Viewing. Lunch for purchase at Catering Area in Exhibit Hall 9. Visit the Cambridge Healthtech Institute (CHI) Pavilion & Posters across from Catering.

iPod® raffl e daily at 13:30 at CHI’s Pavilion. To enter, drop off business card at CHI’s Registration Desk or exhibit booth.

Sponsored by

Sponsored by



Location: Room Bonn

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WEDNESDAY, 6 OCTOBER (Afternoon Sessions)

DATA INTEGRATION AND COLLABORATION: TEARING DOWN THE WALLS BETWEEN THE KNOWLEDGE

SILOS IN THE PHARMACEUTICAL INDUSTRY14:00 Chairperson’s Remarks14:05 Knowledge Engineering: Integrating the External

with the InternalIan Dix, Ph.D., Capability Lead for Knowledge Engineering &

Information Science, Discovery Information, AstraZeneca

14:35 The Reality of Web Services in the Life SciencesCarole Goble, Professor of Computer Science, University of

Manchester

15:05 The New Information Landscape: Towards a New Logic and Practice to Enhance Interoperability and Collaboration in Life Science

Mats Sundgren, Ph.D., Principal Scientist, Global Clinical

Development, AstraZeneca R&D

KNOWLEDGE MANAGEMENT FOR TARGET DISCOVERY: ENHANCING BIOLOGICAL KNOWLEDGE

BY UTILIZING LARGE SCALE DATASETSLocation: Room 15/16

16:00 The Unforseen Consequences of Opportunistic Deuterated Drug Claims, Patent Extraction Feeds and the PubChem Chemistry Rules

Christopher Southan, Ph.D. , Knowledge Engineering,

ChrisDS Consulting

16:30 Novel Knowledge Integration Approaches to MiningGenome-Wide Data Sets

Mario Albrecht, Ph.D., Research Group Leader,

Computational Biology and Applied Algorithmics, Max Planck

Institute for Informatics

17:00 In silico Target Discovery Based on Flexible Pipelining and Meta-Analysis

James Cai, M.D., Head, Biomedical Informatics, Pharma

Research & Early Development (pRED) Informatics,

Hoffmann-La Roche

17:30 Close of Day

DATA INTEGRATION AND COLLABORATION:TEARING DOWN THE WALLS BETWEEN THE KNOWLEDGE

SILOS IN THE PHARMACEUTICAL INDUSTRY

14:00 Chairperson’s Remarks14:05 Knowledge Engineering: Integrating the External

with the InternalIan Dix, Ph.D., Capability Lead for Knowledge Engineering &

Information Science, Discovery Information, AstraZeneca

14:35 The Reality of Web Services in the Life SciencesCarole Goble, Professor of Computer Science, University of

Manchester

15:05 The New Information Landscape: Towards a New Logic and Practice to Enhance Interoperability and Collaboration in Life Science

Mats Sundgren, Ph.D., Principal Scientist, Global Clinical

Development, AstraZeneca R&D


CASE STUDIES OF OPEN COLLABORATIONS AND OPEN SOURCE SOFTWARELocation: Room 13/14

16:00 A Scientifi c Platform for Enhancing Research and Development Productivity and Innovation

Robert Brown, Ph.D., Senior Director, Life

Sciences, Accelrys Inc.

16:30 Collaborative Development of a Registration System for Biologics

Jeremy Packer, Ph.D., Head, Bioinformatics, Abbott

17:00 Building Tools for Collaborative and Open Projects in Biology

Lars Jorgensen, Senior Scientifi c Manager, Production

Software, Sequencing Informatics, The Wellcome Trust Sanger

Institute

17:30 Close of Day

18:30 – 21:00 BIOTECHNICA Night! Traditional Bavarian Beer Hall, dinner reception, live band playing popular music from U.S. Location: Münchner Hall

(Please register to reserve your complimentary ticket ahead of time. No tickets will be available on site.)

Sponsored by




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WEDNESDAY, 6 OCTOBER (Morning Sessions)

SEQUENCING DATA: PROVIDES A PROMISING TOOL FOR MOLECULAR DIAGNOSTICS

9:30 Chairperson’s RemarksKevin Davies, Ph.D., Editor-in-Chief, Bio-IT World

PLENARY KEYNOTES9:35 Applications of Next-Generation Sequencing in an

Academic Medical Hospital: From Single Molecules to a Complete Female Genome Marjolein Kriek, M.D., Ph.D., Clinical Geneticist,

Human & Clinical Genetics, Leiden University Medical Center,

The Netherlands

10:05 Drivers, Challenges and Opportunities to Bring Diagnostics Closer to the Points of NeedRudi Pauwels, Ph.D., Founding Director & CEO,

Biocartis

11:00 Pioneering Personalized Healthcare through Pharma Partnering: A Case Study in Companion Diagnostic Co-Development

Stephen Little, Ph.D., Vice President, Personalized

Healthcare, QIAGEN

11:30 Bringing Next-Generation Sequencing to the ClinicLinh Hoang, M.D., Ph.D., Director, Genomic

Medicine, LIFE Technologies, United States

12:00 PANEL DISCUSSIONModerator: Kevin Davies, Ph.D., Editor-in-Chief, Bio-IT World

Marjolein Kriek, Leiden University Medical Center

Rudi Pauwels, Biocartis

Stephen Little, Qiagen

Linh Hoang, LIFE Technologies



IMAGING SOLUTIONS IN DRUG R&D: DATA ANALYSIS, IMPLEMENTATION, STANDARDS AND QUALITY

9:30 Chairperson’s RemarksYuriy Gankin, Ph.D., Chief Scientifi c Offi cer,

GGA Software Services LLC

9:35 Implementation & Use of PHAEDRA, a Standards-Based System for High-Content Image Analysis and Evaluation

Frans Cornelissen, IT Manager, Janssen Pharmaceutical

9:55 Lessons Learned in Imaging Informatics for Drug Discovery

Gudrun Zahlmann, Ph.D., Manager, Imaging Infrastructure,

pRED, F. Hoffman-La Roche Ltd.

10:15 Quantitative Image Analysis Tools for Biological Research

Ewert Bengtsson, Ph.D., Professor, Center for Image Analysis,

Uppsala University


11:00 Machine Intelligence can Improve the Quality of

Drug and siRNA ScreensPeter Horvath, Ph.D., Head, Image Analysis, Light Microscopy

Centre, ETH Zurich

KEYNOTE PRESENTATIONS:IT & INFORMATICS IN SUPPORT OF DRUG DISCOVERY

11:30 Next-Generation Interfaces and Interaction with Complex Information LandscapesBryn Roberts, Ph.D., Global Head, Informatics,

Pharma Research and Early Development, F.

Hoffmann-La Roche AG

12:00 Informatics for Data Driven Drug Discovery: How to Win the “War” against Data Complexity and SilosJacob deVlieg, Ph.D., Professor & Global Head,

Molecular Design and Informatics, Merck







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THURSDAY, 7 OCTOBER (Morning Sessions)

TRANSLATIONAL INFORMATICS: KNOWLEDGE FERTILIZATION BETWEEN BENCH AND BEDSIDE

9:30 Chairperson’s Remarks9:35 Managing Change Across Interdisciplinary Scien-

tifi c IntegrationPaul Konstant, Manager, Informatics Center of Excellence,

Janssen Pharmaceutical Companies of Johnson & Johnson

10:05 Integrating Clinical and Molecular Data: CASI Project

Thomas Gan, Application Services Senior Analyst, IT, Merck

Research Labs

11:00 Understanding the Business Value ofDynamic Data Aggregation in Life Sciences Manufacturing and Process Development

Joe Rothman, Vice President, Engineering

and Professional Services, Aegis Analytical Corporation

11:30 Visualization and Statistical Pharmacovigilance Methods Using Informatics for Integrating Biology and the Bedside (i2b2)

Shawn Murphy, M.D., Assistant Professor, Neurology, Harvard

Medical School; Medical Director of Research Computing,

Information Services, Partners Healthcare Inc.

12:00 Translational Drug Discovery and Development: An Expedition of Data Integration and Utilization from Preclinical to Clinical

Dongzhou (Jeffery) Liu, Ph.D., Principal Clinical Investigator/

Core Project Leader, Medical Affairs/Clinical Development,

GlaxoSmithKline

Sponsored by


IMPLEMENTING STANDARDS TO REACH PROCESS EFFICIENCY AND INTEROPERABILITY –

METADATA AND BEYOND 9:30 Chairperson’s Remarks9:35 MIBBI: Minimum Reporting Guidelines for

Bioscientists Chris Taylor, Ph.D., Senior Technical Offi cer, The European

Bioinformatics Institute

10:05 Is the Cloud the Panacea for Process Effi ciency? The Elastic-R Case Study

Karim Chine, Director, Cloud Era Ltd.

10:35 Coffee Break

11:00 Now-Generation Data Transport Technology for Life Sciences: Keeping Pace with Innovation

Xingzhe Fan, Ph.D., Research Scientist,

Aspera, Inc.

11:30 iSee - Dissemination of Structural Biology Data to the Masses

Brian Marsden, Ph.D., P.I., Research Informatics, Structural

Genomics Consortium, University of Oxford

ONTOLOGIES AND STATE-OF-THE-ART WEB TECHNOLOGIES

12:00 Semantic Data Integration for Translational Re-search in Neuroscience

Rudi Verbeeck, Ph.D., Program Manager, Informatics

Center of Excellence, Janssen Pharmaceutical Companies of

Johnson & Johnson



Sponsored by




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ONTOLOGIES AND STATE-OF-THE-ART WEB TECHNOLOGIES

14:30 Chairperson’s Remarks14:35 Keeping Track of Data and What the Data are

About: An Exploration in Realism-Based Ontology for Translational Research

Werner Ceusters, Ph.D., Director, Ontology Research Group,

NYS Center of Excellence in Bioinformatics & Life Sciences

15:05 Shared Molecular Network Models of Unrelated Diseasomes - Unraveling the Conundrum of Network Medicine

Reena Gollapudy, Ph.D., Lead Consultant, IHL, Infosys

Technologies Ltd.

16:00 How Can a “Normal End User” Become a Web Service Consumer?

Christian Hauck, Ph.D., Knowledge Management and


16:30 Effi cient Web-Browsing for the Life ScientistReinhard Schneider, Ph.D., Team Leader, Structural and

Computational Biology Unit, European Molecular Biology

Laboratory (EMBL)

17:00 A Data Warehousing Approach for the Management of Clinical and Operational Information: Specifi c Challenges within Pharma Development

Norbert Fritz, Ph.D., Development Lead, Business

Intelligence Warehouse, Information Management - Product

Development Operations, F. Hoffmann-La Roche Ltd


THURSDAY, 7 OCTOBER (Afternoon Sessions)

ONTOLOGIES AND STATE-OF-THE-ART WEB TECHNOLOGIES (continued)

14:30 Chairperson’s Remarks14:35 Keeping Track of Data and What the Data are

About: An Exploration in Realism-Based Ontology for Translational Research

Werner Ceusters, Ph.D., Director, Ontology Research Group,

NYS Center of Excellence in Bioinformatics & Life Sciences

15:05 Shared Molecular Network Models of Unrelated Diseasomes - Unraveling the Conundrum of Network Medicine

Reena Gollapudy, Ph.D., Lead Consultant, IHL, Infosys

Technologies Ltd.


16:00 How Can a “Normal End User” Become a Web Service Consumer?

Christian Hauck, Ph.D., Knowledge Management and


16:30 Effi cient Web-Browsing for the Life ScientistReinhard Schneider, Ph.D., Team Leader, Structural and

Computational Biology Unit, European Molecular Biology

Laboratory (EMBL)

17:00 A Data Warehousing Approach for the Management of Clinical and Operational Information: Specifi c Challenges within Pharma Development

Norbert Fritz, Ph.D., Development Lead, Business Intelligence

Warehouse, Information Management - Product Development

Operations, F. Hoffmann-La Roche Ltd


Poster Presenters

Austrian Institute of TechnologyNext Generation

Sequencing (NGS) in Non-Model Species – Challenges and

Obstacles

BioWisdom Ltd.The Power of

Metadata

European Bioinformatics InstituteAutomated

Functional Prediction of Non-Characterized Biological Data

A New

Bioinformatics Analysis Tools Framework at EMBL–EBI

Biological Data Integration and

Import Framework for Protein Sequence Databases

German Cancer Research Center (DKFZ)

Data Integration in Systems Biology

Ingenuity SystemsAnalysis of Molecular Profi ling Data to Understand

Mechanisms of Disease, Targets and Biomarkers

Max Planck Institute for Biophysical Chemistry

CyMoBase - The Reference Database for

Cytoskeletal and Motor Proteins

WebScipio A Web Tool

for Gene Structure Prediction

National Institute of Biology

Visualization of Transcriptomics Data in Metabolic

Pathways: Extending the MapMan Ontology to Grape and Potato

Optibrium Ltd.Guiding Focused Design of

Potent Leads with Improved Metabolic Stability

University of PretoriaSeqWord MetaLingvo Program for Clustering and

Binning Metagenomic Sequences


Aspera, Inc.5900 Hollis Street, Suite EEmeryville, CA 94608 USAwww.asperasoft.comAspera is the creator of next-generation transport technolo-

gies that move the world’s largest data sets at maximum

speed regardless of fi le size, transfer distance and network

conditions. Aspera’s core technology delivers unprecedented

control over bandwidth, complete security and uncompro-

mising reliability. About one thousand organizations across

a variety of industries rely on Aspera for the critical transport

of their data.

Accelrys10188 Telesis Court, Suite 100San Diego, CA 92121 USAwww.accelrys.comAccelrys develops and commercializes scientifi c business

intelligence software and solutions that help accelerate

science for clients in the Life Sciences, Energy, Chemicals,

Aerospace, and Consumer Packaged Goods industries. Our

solutions are used by biologists, chemists, materials scien-

tists, IT and business professionals to aggregate, analyze,

simulate, and visualize scientifi c data.

Aegis Analytical Corporation1380 Forest Park Circle, Suite 200Lafayette, CO 80026 USAwww.aegiscorp.comAegis provides Manufacturing Intelligence solutions that

drive a lean supply chain and accelerate revenue with a

proven approach to data access, aggregation and analytics.

Leading life science manufacturers increase profi ts by using

the company’s enterprise-class software platform, Discover-

ant ®, to improve process predictability, quality and yield

and accelerate technology transfer.

Applied Biosystems Inc./Life Technologieswww.appliedbiosystems.comThe Applied Biosystems brand is a global leader in providing

innovative, optimized instrument systems and workfl ows to

accelerate academic and clinical research, drug discovery

and development, pathogen detection and forensic DNA

analysis. Through its Applied Biosystems and Invitrogen

brand of reagents, kits and bench-top devices, Life Tech-

nologies markets the most comprehensive portfolio of

solutions for molecular and cell biology. Life Technologies

(www.lifetech.com) is a global biotechnology tools company

dedicated to improving the human condition. Our systems,

consumables and services enable researchers to accelerate

scientifi c exploration, driving to discoveries and develop-

ments that make life even better.

BioTeam Inc.7 Derosier DriveMiddleton, MA 01949 USAwww.bioteam.netAs a high-performance consulting practice, BioTeam delivers

solutions to address the IT, storage, and data management

challenges faced by scientists adopting next-generation

sequencing technologies. We are dedicated to delivering

objective, technology agnostic solutions to the life science

researchers. From objective counsel to hands-on implemen-

tation, BioTeam enables science by bringing together tech-

nologies that turn research into results.

GGA Software Services LLC One Miffl in PlaceCambridge, MA 02138 USAwww.ggasoftware.comSince 1994, GGA Software Services has offered world-class

outsourced scientifi c informatics services to major pharma-

ceutical companies as well as early-stage life science fi rms.

Leveraging its 400-person development facility in St. Peters-

burg, Russia, GGA provides superior software engineering,

algorithm development, and data curation services in bioin-

formatics and cheminformatics.

Hewlett Packard200 Forest StreetMarlborough, MA 01752 USAwww.hp.com/go/lifesciencesAs a world-leading information technology company, HP ap-

plies new thinking and ideas to create more simple, valuable

and trusted experiences with technology. Our focus is to

continuously improve the way our customers live and work

through technology products and services, form the indi-

vidual consumer to the largest enterprise.

Isilon3101 Western AvenueSeattle, WA 98121 USAwww.isilon.comIsilon Systems is the proven leader in scale-out NAS. Isilon’s

storage systems enable life science and bioinformatics orga-

nizations to easily and cost-effectively manage the deluge of

data being produced by today’s DNA sequencing platforms

and other next-generation instruments.

Panasas, Inc.7200 The QuorumOxford Business Park NorthGarsington Road, Oxford OX4 2JZwww.panasas.comPanasas, Inc., the leader in high-performance scale-out NAS

storage solutions, enables enterprise customers to rapidly

solve complex computing problems, speed innovation and

bring new products to market faster. All Panasas solutions

leverage the patented PanFS™ storage operating system to

deliver exceptional performance, scalability and manageabil-

ity. Panasas systems are optimized for demanding storage

environments in the energy, government, fi nance, manufac-

turing, bioscience and higher education industries.

QIAGEN GmbHQIAGEN Strasse 140724 Hilden, Germanywww.qiagen.com QIAGEN acquired DxS, in September 2009 to create a Cen-

ter of Excellence in Companion Diagnostics. QIAGEN work

with pharmaceutical companies to support development

of targeted cancer therapies by providing biomarkers and

companion diagnostics. QIAGEN‘s product portfolio includes

real-time PCR and Pyrosequencing assays for K-RAS to iden-

tify colorectal cancer patients more likely to benefi t from

anti-EGFR therapies such as panitumumab and cetuximab,

EGFR to aid doctors in selecting lung cancer patients suitable

for treatment with tyrosine kinase inhibitors, B-RAF and PI3K

genes among others.

Quantum141 Innovation DriveIrvine, CA 92617 USAwww.quantum.comQuantum StorNext enables you to run more research or

clinical experiments and instantly share results across your

entire research community. Proven at Swiss Institute of

Bioinformatics and the Human Genome Sequencing Center

at Baylor College, StorNext is an end-to-end data manage-

ment software solution for your next generation life sciences

technologies.

SCYNEXIS, Inc. 3501 C Tricenter BoulevardDurham, NC 27713 USAwww.scynexis.comSCYNEXIS, Inc. provides integrated, effi cient and innova-

tive drug discovery and development solutions to our global

health and pharmaceutical partners. We have delivered

eleven pre-clinical drug candidates over the last fi ve years.

Our HEOS® technology is a cloud-based drug research infor-

mation management software that supports geographically

distributed collaborations.

Strand Scientifi c Intelligence, Inc.548 Market Street, Suite 82804San Francisco, CA 94104 USAwww.strandsi.comStrand Scientifi c Intelligence, (Strand) is a privately held

company that has pioneered the practice of Scientifi c In-

telligence in life and health sciences. Strand’s powerful

computational algorithms combined with exceptional life

and health sciences expertise have resulted in products

and customized solutions that span the data integration and

analysis, knowledge management, experimental, clinical,

and pipeline decisions continuum in diverse scientifi c areas.

Sponsor Descriptions

Thank You to Our Media Partners


Second Annual

Exhibition Grounds Hannover | Germany

5-7 October 2010

Organized & Managed byCambridge Healthtech Institute

www.healthtech.com

PEGSummitEurope.com

Held in Conjunction with: Europe’s No.1 Event in Biotechnology and Life Sciences

6-7 October

Empowered Bispecifi cAntibodies

Diffi cult Protein Expressionand Purifi cation

5-6 October

Novel Antibody Constructsand Alternative Scaffolds

Protein Expression andCell Line Development

KEYNOTE PRESENTERS:

Josefi n-Beate HolzChief Medical Offi cerAblynx NV

Bernhardt L. TroutPh.D., Director, Novartis-MIT Center for Continuous Manufacturing

John BirchPh.D., Consultant

Premier Sponsor: Corporate Sponsors:

Corporate Support Sponsors:

PEGSummitEurope.com P-12 Please note: Video and/or audio recording of


CONFERENCE-AT-A-GLANCEMonday, 4 October

8:20-9:30 Pre-Conference Short Course Registration (separate registration required) Convention Center in front of Room 1

14:00-17:00 Short Course 3: Protein Aggregation in Biopharmaceutical Products Location: Room 16


18:30 Biotechnica Opening and European Award Ceremony plus Reception Location: Room 1

Tuesday, 5 October


9:30-10:35Engineering the Fc Regions for Antigen Binding, Effector Function & Enhanced Half-Life Room 1A

Vectors, Tags, Chaperones, and Genes Room 1B


11:00-12:30 Novel Delivery Products Room 1A Vectors, Tags, Chaperones, and Genes Room 1B

12:30-14:20Exhibit & Poster Viewing. Lunch for purchase at Catering Area in Exhibit Hall 9. Visit the Cambridge Healthtech Institute (CHI) Pavilion across from Catering. iPod® raffle daily at 13:30 at CHI’s Pavilion. To enter, drop off business card at CHI’s Registration Desk or exhibit booth.

14:30-15:35 Technologies that Select for Enhanced Half-Life & Stability Room 1A Novel Hosts and Unique Platforms Room 1B

15:35-16:00 Refreshment Break Sponsored by

Outside Session Room

16:00-18:15Focus on Screening & Selection of Drug Candidates for Specific Purposes Room 1A

Novel Hosts and Unique Platforms Room 1B

18:15-19:15 Interactive Breakout Discussion Groups Room 1A Interactive Breakout Discussion Groups Room 1B


Wednesday, 6 OctoberTRACK 1: Novel Antibody Constructs and Alternative Scaffolds

Location: Room 1ATRACK 2: Protein Expression and Cell Line Development

Location: Room 1B

9:30-10:35 Accessing Difficult to Reach Targets Room 1A Mammalian Cell Expression Room 1B


11:00-12:30 Focus on Affinity and Specificity Room 1A Mammalian Cell Expression Room 1B


13:45 Close of Conference Close of Conference


14:00-15:35Improving Targeting with Antibody-Drug Conjugates: AddressingSelectivity and Delivery Room 1A

Problem Protein Solutions Room 1B

15:35-16:00 Refreshment Break Sponsored by Outside Session Room

16:00-17:30Improving Targeting with Antibody-Drug Conjugates: Addressing Selectivity and Delivery Room 1A

Problem Protein Solutions Room 1B


Thursday, 7 October

9:30-10:35 New Bispecific & Multi-Valent Constructs Room 1A Automation and High-Throughput Room 1B

10:35-11:00

Coffee Break Sponsored by Outside Session Room

11:00-12:30 New Bispecific & Multi-Valent Constructs Room 1A Automation and High-Throughput Room 1B


14:30-15:35Engineering for Enhanced Stability and Manufacturability of Proteins Room 1A

Unique Proteins – Unique Techniques Room 1B


16:00-17:30Engineering for Enhanced Stability and Manufacturability of Proteins Room 1A

Polypeptide Expression Room 1B


PEGSummitEurope.com P-13



Poster Presenters

Affi med Therapeutics AG

AFM13 – Bispecifi c Tetravalent TandAb for

Treating Hodgkin Lymphoma

Agilent Technologies

Specifi c Detection of Proteins by Immunoprecipitation

Combined with Highly Sensitive Protein Sizing on Microchips

BioSilta Oy

High Cell Density and

Improved Yield of Soluble Protein in Shake Flask Cultures Can

Be Achieved Using EnPresso™, a Novel Fed-Batch Cultivation

Medium

Boehringer Ingelheim RCV GmbH & Co. KG

Manufacturing of an Anticalin® by

Intracellular Soluble Expression in E. coli: A Case Study

Celgene CorporationExpression

and Purifi cation of Spingosine Kinase, a Member of the Lipid

Kinase Family

Cellectis bioresearch

Targeted Transgene

Integration in a CHO-S Hotspot for the Fast and Reproducible

Production of High Protein Titers









DataRoom 14











Room Bonn







Track 3 Room 13/14

Track 4 Room 15/16










TUESDAY, 5 OCTOBER (Morning Sessions)

Novel Antibody Constructs and Alternative Scaffolds

Location: Room 1A

Protein Expression and Cell Line Development

Location: Room 1B

Track 1 Track 2

Vectors, Tags, Chaperones, and Genes9:30 Chairperson’s RemarksArnaud Poterszman, Ph.D., Research Director (CNRS), Structural Biology and Genomics, IGBMC-CERMB9:35 KEYNOTE PRESENTATION

Protein Expression in Mammalian Cells: Past Perspective, Future Potential

John Birch, Ph.D., Consultant

10:05 A Novel Fusion System for Soluble Overexpression of Recombinant Proteins in Escherichia coli

Sofia Costa, Researcher, Biological Engineering, IBBCEB, University of Minho


11:00 Production of Recombinant Human Multi-Protein Transcription Factor Complexes

Arnaud Poterszman, Ph.D., Research Director (CNRS), Structural Biology and Genomics, IGBMC-CERMB

11:30 Minicircles (MCs): Overcoming the Limitations of Transient Expression Systems

Juergen Bode, Ph.D., Professor, Medical School Hannover

12:00 How a Strong Expertise in Target Proteins Expression can Become an Added Value for Bioprocess Development

Hervé Ginisty, Ph.D., CSO, GTP Technology

12:15 From EnBase to EnPresso - Novel Instant Solutions Facilitate High Level Recombinant Protein and Plasmid Production

Peter Neubauer, Ph.D., Professor, Technische Universität Berlin, and Scientific Advisor, BioSilta Oy

Sponsored by

Sponsored by


Engineering the Fc Regions for Antigen Binding, Effector Function and

Enhanced Half-Life9:30 Chairperson’s RemarksChristian Heinis, Ph.D., Laboratory of Therapeutic Proteins and Peptides, Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL)

9:35 Modular Antibodies: Introducing Antigen-Binding Sites in the Fc Region of IgG

Max Woisetschläger, Ph.D., Director, Target Biology, f-star

10:05 IL-17 Neutralizing Fynomers: Making Use of Fc Fusion Proteins

Dragan Grabulovski, Ph.D., Chief Scientific Officer, Covagen, A.G.


Novel Delivery Products11:00 Exploiting the Biophysical Properties of

Centyrins for Alternative Routes of Delivery Steve Jacobs, Ph.D., Lead Scientist, Centyrex, a J&J RedScript Venture

11:30 Anticalins: A Differentiated Biologics Drug Class for Novel Delivery, Broad Target Space and New Modes of Action

Kristian H. Jensen, Ph.D., COO, Pieris AG

12:00 Glycan-Binding Decoy Proteins with Strong Anti-Inflammatory Activity Derived from the CellJammer® Platform Technology

Andreas Kungl, CSO, ProtAffin Biotechnologie AG

Sponsored by

Enzo Life Sciences, Inc.

Rapid Assessment of Protein Stability and Aggregation

in Protein-Based Pharmaceuticals

Fraunhofer Institute for Cell Therapy and Immunology (IZI)

Improving the Selection from Phage Display Libraries

Friedrich-Alexander University of Erlangen-Nuremberg

A Recombinant

Trispecific Single-Chain Fv Derivative Directed Against CD123

and CD33 Mediates Effective Elimination of Acute Myeloid

Leukemia Cells by Dual Targeting

Georg-Speyer-Haus

Identification of HIV-Neutralizing Antibodies and Their Epitopes

from HIV Controllers

PEGS Poster Presenters (continued)


iPod® raffle daily at 13:30 at CHI’s Pavilion. To enter, drop off business card at CHI’s Registration Desk or exhibit booth.


TUESDAY, 5 OCTOBER (Afternoon Sessions)


Location: Room 1A


Location: Room 1B

Track 1 Track 2

Novel Hosts and Unique Platforms14:30 Chairperson’s RemarksMatthias Mack, Ph.D., Head, Institute for Technical Microbiology, Mannheim University of Applied Sciences14:35 A High-Throughput Microtiter Plate-Based

Screening Method for the Detection of Full-Length Recombinant Proteins

Matthias Mack, Ph.D., University of Applied Sciences15:05 Robo-Lector – A Novel Platform for Automated

High-Throughput Cultivations in Microtiter Plates with High Information Content

Frank Kensy, Managing Director, m2p-labs GmbH

15:35 Refreshment Break Sponsored by

16:00 Boosting Secreted Expression of Biologics from Pichia Pastoris with Novel Tools and Technologies

Thomas Purkarthofer, Ph.D., Head of Business Development, VTU Technology GmbH16:30 A Novel T7 RNA Polymerase-Dependent

Expression System for High-Level Protein Production in the Phototrophic Bacterium Rhodobacter capsulatus

Thomas Drepper, Ph.D., Institute of Molecular Enzyme Technology (IMET), Heinrich-Heine-Universität Düsseldorf17:00 Rapid Protein Quantification by Applying

BioLayer InterferometryArnout Gerritsen, Director Assay & Bioanalytical Science, Genmab17:30 Lactococccus lactis P170 Expression System: A

Novel Secretion-Based Expression System for Production of Recombinant Proteins

Soeren Madsen, Ph.D., Group Leader, Bacterial Expression, Bioneer A/S

Sponsored by

Technologies that Select for Enhanced Half-Life and Stability

14:30 Chairperson’s RemarksJosefin-Beate Holz, Chief Medical Officer, Ablynx NV

14:35 From Clinical Imaging to Serum Half-Life Extension Using HER2-Specific Affibody Molecules

Fredrik Y. Frejd, Ph.D., Project Manager, Biotherapeutics, Affibody AB

15:05 PASylation: A Superior Technology to Extend the Plasma Half-Life of Therapeutic Proteins

Arne Skerra, Ph.D., CEO, XL-protein GmbH

15:35 Refreshment Break Sponsored by

Focus on Screening and Selection of Drug Candidates for Specific Purposes

16:30 Tn3: A New Platform for Non-Antibody Protein Drugs

Manuel Baca, Ph.D., Principle Scientist, Antibody Discovery & Protein Engineering, MedImmune, Inc.

17:00 Generating A Best-in-Class DARPin Therapeutic for the Treatment of Ophthalmic Neovascularization Diseases

H. Kaspar Binz, Ph.D., Vice President Technology, Molecular Partners AG

17:30 Challenges in Domain Antibody DevelopmentThomas Sandal, Head, Microbial Process Research, GlaxoSmithKline Research & Development

18:15 Interactive Breakout Discussion Groups1. Measures to Increase Half-Life of the ProductModerator: Christian Heinis, Ph.D.,Laboratory of Therapeutic Proteins and Peptides, Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL) 2. How to Efficiently get to Lead Molecules: Measures and

MethodsModerator: H. Kaspar Binz, Ph.D., V.P. Technology, Molecular Partners AG 3. Antibodies Versus Alternative Scaffolds: Pros and ConsModerator: Arne Skerra, Ph.D., CEO, XL-protein GmbH

4. Issues to Do With Formulation and DeliveryModerator: Kristian H. Jensen, Ph.D., Chief Operating Officer, Pieris AG5. Imaging to Check for Targeting and Half-lifeModerator: Fredrik Y. Frejd, Ph.D., Project Manager, Biotherapeutics, Affibodyn6. Immunogenicity Risk Assessment Regarding Novel

ProteinsModerator: Josefin-Beate Holz, Chief Medical Officer, Ablynx NV

Additional Breakout Discussions, please refer to daily slides.



Sponsored by



Location: Room 1A


Location: Room 1B

Track 1 Track 2

Mammalian Cell Expression9:30 Chairperson’s RemarksBernd Voedisch, Ph.D., Postdoctoral Researcher, Geisse Group, Novartis

9:35 Transient Expression in CHO Cells: A Balancing Act between Multiple Parameters

Bernd Voedisch, Ph.D., Postdoctoral Researcher, Geisse Group, Novartis

10:05 A Pipeline for the Production of Glycoproteins for Structural Biologye

Raymond Owens, Ph.D., Oxford Protein Production Facility, Welcome Trust Centre for Human Genetics

Advances in Protein Science

11:00 CAP: A New Protein Production Platform based on Immortalized Human Amniocytes

Hartmut Tintrup, Ph.D., Director Marketing & Business Development, Cevec Pharmaceuticals GmbH

11:30 Pseudomonas for Protein Expression: Learning from Versatile Hosts

Frank Rosenau, Ph.D., Head, Microbial Expression Technology Group, Institute of Molecular Enzyme Technology, Heinrich-Heine-University Duesseldorf

12:00 Protein Aggregation Profile of the Bacterial Cytosol

Salvador Ventura, Ph.D., Group Leader, Institut de Biotecnologia Biomedicina, Universitat Autonoma de Barcelona


Sponsored by


Accessing Difficult to Reach Targets9:30 Chairperson’s RemarksThomas Sandal, Head, Microbial Process Research, GlaxoSmithKline Research & Development

9:35 KEYNOTE PRESENTATION: Exploiting Nanobody® Advantages to Target Challenging Proteins: From Discovery to in vivo Proof-of-Concept for an Anti-GPCR Nanobody

Josefin-Beate Holz, Chief Medical Officer, Ablynx NV

10:05 Accelerating scFv Antibody Fragments for Topical Applications into the Clinic

David Urech, Ph.D., Head, Research & Development, ESBATech LLC, an ALCON Biomedical Research Unit


Focus on Affinity and Specificity 11:00 XTENylation Enables Long Half-Life and

Maximum in vivo Potency via Precise Tuning of Drug-Target Affinity

Volker Schellenberger, Ph.D., Vice President, Drug Discovery, Amunix, Inc.

11:30 Bicyclic Peptides with Tailored Binding Specificities

Christian Heinis, Ph.D., Laboratory of Therapeutic Proteins and Peptides, Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL)

12:00 ISMIPTM and SCORPIONTM Proteins: Novel, Mono- or Multi-Specific Therapeutic Proteins for Oncology and Autoimmune Diseases

Kendall M. Mohler, Ph.D., Senior Vice President and Chief Scientific Officer, R&D, Trubion Pharmaceuticals, Inc.


iPod® raffle daily at 13:30 at CHI’s Pavilion. To enter, drop off busines card at CHI’s Registration Desk or exhibit booth.



Georg-Speyer-Haus (continued)

Selection of Lassa Fever Virus Specific Single Chain Fv Antibody Fragments by Phage Display

GlaxoSmithKline Biopharm R&D

Structure-Based Re-Engineering of a Humanised Monoclonal Antibody Following Immunogenicity Assessment by an In Silico Prediction Method



Empowered Bispecific Antibodies and Antibody-Drug Conjugates

Location: Room 1A

Difficult Protein Expression and Purification

Location: Room 1B

Track 3 Track 4


Problem Protein Solutions14:00 Chairperson’s RemarksKenneth Lundstrom, Ph.D., CEO, PanTherapeutics

14:05 Cell-Free Production of Difficult Pharmaceutical Targets: Case Studies of G-Protein Coupled Receptors and Alzheimer’s Disease Related Proteins

Frank Bernhard, Ph.D., Centre for Biomolecular Magnetic Resonance, Institute for Biophysical Chemistry, University of Frankfurt/Main

14:35 Semliki Forest Virus Vectors: Versatile Tools for Protein Production

Kenneth Lundstrom, Ph.D., CEO, PanTherapeutics

15:05 High-Level Production and Characterization of a G-Protein Coupled Receptor Signaling Complex

Stephen Marino, Ph.D., Department of Molecular Membrane Biology, Max Planck Institute of Biophysics

16:00 Advancing Synthetic Gene DesignClaes Gustafsson, Ph.D., Vice President, Marketing and Sales, DNA2.0

16:30 A Simplified Protocol for the Refolding and Purification of Recombinant Human -Secretase 1 (BACE1) Expressed in Escherichia coli for Structural Studies

Zhongren Wu, Research Fellow, Biochemistry, Vitae Pharmaceuticals

17:00 EasyProt: An Innovative Protein Expression System Based on the Secretion System Type III of Pseudomonas aeruginosa

Audrey Le Gouellec, Ph.D., Assistante Hospitalo-Universitaire, HumProTher Lab, Joseph Fourier University

17:30 Close of Day

Sponsored by

Improving Targeting with Antibody- Drug Conjugates: Addressing Selectivity

and Delivery 14:00 Chairperson’s RemarksStefan Barth, Ph.D., Head, Department of Pharmaceutical Product Development, Fraunhofer IME

14:05 Recombinant Human Multi-Domain Fusion Proteins

Stefan Barth, Ph.D., Head, Department of Pharmaceutical Product Development, Fraunhofer IME

14:35 Antibodies-Conjugated Nanoparticles for Targeted Drug Delivery

Roland Kontermann, Ph.D., Professor, Biomedical Engineering, Institute of Cell Biology & Immunology, University of Stuttgart

15:05 Toxicity-Reducing Potential of Extracorporeal Affinity Adsorption Treatment in Combination with Empowered Antibodies in a Syngeneic Rat Tumor Model

Rune Nilsson, Ph.D., Associate Professor, Department of Oncology, Lund University


Selected Poster Presentations

16:00 A Recombinant Trispecific Single-Chain Fv Derivative Directed Against CD123 and CD33 Mediates Effective Elimination of Acute Myeloid Leukemia Cells by Dual Targeting

Georg H. Fey, Ph.D., Department of Biology, University of Erlangen-Nuremberg

16:15 Generation and In Vitro Characterization of Bispecific c-Met – HER1/HER2 Antibodies for the Treatment of Cancer

Raffaella Castoldi, Ph.D., Pharma Research and Early Development, Roche Diagnostics GmbH

16:30 Close of Day

18:30 – 21:00 BIOTECHNICA Night! Traditional Bavarian Beer Hall, dinner reception, live band playing popular music from U.S. Location: Münchner Hall

(Please register to reserve your complimentary ticket ahead of time. No tickets will be available on site.)




Location: Room 1A


Location: Room 1B

Track 3 Track 4

THURSDAY, 7 OCTOBER (Morning Sessions)

Automation and High-Throughput9:30 Chairperson’s RemarksGert E. Folkers, Ph.D., NMR Spectroscopy Research Group, Bijvoet Center for Biomolecular Research, Utrecht University

9:35 Production of scFv Fragments on the G/L Scale in the Cytoplasm of E. coli

Dominique Desplancq, Ph.D., Research Scientist, Biotechnologie des Interactions Moleculaires, Institut de Recherche de l’Ecole de Biotechnologie de Strasbourg

10:05 Parallel Protein Production and Verification of Protein Product Using a High-Throughput Method in Plate Format

Louise Yderland, Group Leader, Proteomics, School of Biotechnology, Royal Institute of Technology, Albanova Universitetscentrum


11:00 An Accelerated Protein Stability Testing Assay For Optimizing Purifica- tion Steps and Storage Conditions

Wayne F. Patton, Ph.D., Chief Scientific Officer, Enzo Life Sciences

11:30 Automated Multigene Recombineering for Protein Complex Production in Prokaryotic and Eukaryotic Hosts

Imre Berger, Ph.D., Group Leader, Berger Group, EMBL-Grenoble

12:00 High-Throughput Technologies for Preparation of High Value Proteins

Gert E. Folkers, Ph.D., NMR Spectroscopy Research Group, Bijvoet Center for Biomolecular Research, Utrecht University

Sponsored by


New Bispecific and Multi-Valent Constructs: Optimizing Discovery for Best Results Downstream9:30 Chairperson’s RemarksLutz Jermutus, Ph.D., FRSC, Senior Director, Technology, MedImmune

9:35 Optimization of Variable Domain Combination, Orientation and Linkers to Construct Dual Variable Domain (DVD) – Ig TM Molecules

Tariq Ghayur, Ph.D., Senior Principal Scientist & Research Fellow, Biologics, Abbott Bioresearch Center, Inc.

10:05 Novel Multispecific ConstructPeter Kiener, CEO, Zyngenia

10:35 Coffee Break Sponsored by 11:00 Development of a Bispecific TandAb for Clinical

Studies: Issues Relating to Immunogenicity, Production and Formulation

Melvyn Little, Ph.D., CSO, Affimed Therapeutics AG

11:30 Bispecific T Cell-Engaging Antibodies of the BiTE Class

Patrick Baeuerle, Ph.D., CSO & Senior Vice President, R&D, Micromet

12:00 Improving the in vivo Utility of Targeted Toxins by Rendering them Bispecific

Daniel A. Vallera, Ph.D., Lion Scholar and Director, Section on Molecular Cancer Therapeutics, Professor of Therapeutic Radiology, University of Minnesota Cancer Center



Hebrew University of Jerusalem

Development of

Superactive Leptin Antagonists Using Yeast Surface Display

Methodology

ICx TechnologiesFaststep™: A New Approach to

Increase Throughput for Screening and Kinetics

Immunostep, S.L.

New Methods and Approaches

for the Development of Antibodies Against Site-Point Mutated

Proteins

Keio UniversityNovel

Display Methods Based on In Vitro Compartmentalization for

Selecting Fab Fragments

MedImmune, LLC

Engineering a High Affinity, Ultrapotent Human Anti-IL-15

Antibody: Crystal Structure Reveals an Alpha-Helix in VH CDR3 as

Key Component of Paratope




Location: Room 1A


Location: Room 1B

Track 3 Track 4

THURSDAY, 7 OCTOBER (Afternoon Sessions)

Unique Proteins – Unique Techniques14:30 Chairperson’s RemarksJames Groarke, Ph.D., Senior Research Investigator II, Protein Structure, Novartis Institute for Biomedical Research

14:35 The Baculovirus Expression Platform: Recent Advances & More Lessons Learned

James Groarke, Ph.D., Senior Research Investigator II, Protein Structure, Novartis Institute for Biomedical Research

15:05 A Simple High-Throughput Purification Method for Hit Edentification in Protein Screening

Emma Cummins, M.Sc., Senior Scientist, Global Biotherapeutic Technologies, Pfizer


Polypeptide Expression16:30 Elastin-Like Polypeptides – Up-and-Coming

Tools for Recombinant Protein Expression and Biomedical Application

Doreen M. Floss, Ph.D., Researcher, Institute of Biochemistry, Christian-Albrechts-University

17:00 Secreted Production of an Elastin-Like Polypeptide by Pichia pastoris

Roelof Schipperus, M.S., Agrotechnology and Food Sciences Group, Wageningen University and Research Center


Engineering for Enhanced Stability and Manufacturability of Proteins

14:30 Chairperson’s RemarksBernhardt L. Trout, Ph.D., MIT

14:35 KEYNOTE PRESENTATION Incorporation of Developability and Manufacturability in Therapeutic Antibody DiscoveryBernhardt L. Trout, Ph.D., Director, Novartis-

MIT Center for Continuous Manufacturing; Director, Concourse; Co-Chair, Singapore-MIT Alliance, Chemical and Pharmaceutical Engineering; Professor, Department of Chemical Engineering, MIT

15:05 In silico Methods to Reduce Development Risks in Biotherapeutics: Engineering Optimal Lead Compounds

Jesús Zurdo, Ph.D., Head of Innovation, LCM Development Services, Lonza Biologics plc


16:30 Screening Antibody Candidates for Manufacturability, Stability, and Deliverability

Andrew Kosky, Senior Manager, Early Stage Pharmaceutical Development, Genentech, Inc.

17:00 Engineered Ig-Like Bispecific Molecules with Enhanced Therapeutic Potential

Justin Caravella, Ph.D., Scientist, Physical Biochemistry, Drug Discovery, Biogen Idec, Inc.


RigshospitaletOptimized Tagging of Recombinant Proteins Produced in Drosophila S2 Cells Using the Third Domain of

the Urokinase Receptor for Efficient One-Step Purification

Roche Diagnostics GmbHGeneration and In Vitro

Characterization of Bispecific c-Met – HER1/HER2 Antibodies for the Treatment of Cancer

Sanofi Pasteur

Antibiotic-Free Selection in E. coli: New Considerations for Optimal Design and Improved Production

Tohoku UniversityHighly Enhanced Cytotoxicity of a Dimeric Bispecific Diabody, the

Humanized EGFR x CD3 Tetrabody

University of CopenhagenHigh Throughput FcRn Binding Assays

University of LisbonAccessing Combinatorial Strategies to Multimerize Libraries of Single-Domain

Antibodies

University of SalamancaSelf-Assembling Protein Microarrays and Surface

Plasmon Resonance Imaging to Study High-Throughput Protein Interactions of p53 and Mdm2



Sponsor Descriptions

BioSiltaP.O. 4300 FI-90014 Oulu Finlandwww.BioSilta.com

BioSilta specializes in microbial cell cultivation and

protein production. The patented EnBase® media

technology provides a cultivation environment with

enzymatic glucose-control and pH maintenance with-

out the need for traditional mechanical pumps. The

BioSilta products offer solutions for cultivations rang-

ing from multi-well plates to small-scale bioreactors.

Cevec Pharmaceuticals GmbHGottfried-Hagen-Str. 6251105 Köln, Germanywww.cevec-pharmaceuticals.com/

CEVEC’s superior protein expression technologies

CAP and CAP-T are designed for stable and transient

protein production and achieve highest protein yields

with authentic human glycosylation patterns. The

immortalized cells are derived from primary human

amniocytes and meet highest ethical standards.

Already adopted to serum-free growth conditions, they

can be very effi ently transfected with commercially

available transfection reagents and are optimized to

grow in a variety of fl ask/wave formats up to large-

scale processing in bioreactors.

Crucell Archimedesweg 4-62333 CN LeidenYpsilon building, Newtonweg 12333 CP Leiden, The Netherlandswww.crucell.com

Crucell is a leading biotechnology company developing

vaccine, antibody and therapeutic protein products and

technologies. We aim to protect human health through

our commitment to combat infectious diseases, and in

the partnerships we forge in facing that challenge. One

of our key technologies is the Per.C6 human cell line

technology which offers remarkable high-yields and

low costs for the production of biologics

1430 O’Brien Drive, Suite EMenlo Park, CA 94025 USAwww.DNA20.com

DNA2.0 is the leading synthetic genomics company

and the fastest provider of synthetic genes, based in

the US with a global customer base encompassing

industry, academia, and government. DNA2.0 has

developed novel gene redesign algorithms to ensure

the synthetic genes encode high protein expression

levels and effi cient protein engineering algorithms.

DNA2.0 has provided genes to thousands of custom-

ers, for whom it has synthesized many millions of base

pairs. The tools and applications brought to market by

DNA2.0 are transforming biology into an engineering

discipline.

Enzo Life Sciences International, Inc. 5120 Butler PikePlymouth Meeting, PA 19462 USAwww.enzolifesciences.com

Enzo Life Sciences, incorporating ALEXIS®, Assay

Designs®, BIOMOL® and Stressgen®, offers a

comprehensive panel of innovative life science re-

agents. Antibodies, enzymes, proteins, small molecule

inhibitors, and assay kits are available for research

in cancer, cellular stress, cell death, epigenetics,

genomics, immunology, neuroscience, signal transduc-

tion, and ubiquitin & proteasomes.

ForteBio 1360 Willow Road, Suite 201Menlo Park, CA 94025 USAwww.fortebio.com

ForteBio markets a novel, label-free, 96 or 384-well

format detection platform that includes instrument

hardware, biosensors and data analysis software to

measure affi nity, kinetics, and concentration in crude

or purifi ed samples. This real-time dip and read meth-

od allows greater throughput and cost-effectiveness in

many applications compared to existing methods such

as SPR, ELISA and HPLC.

GTP Technology Rue Pierre et Marie Curie, BP48184 31681 Labege, Francewww.gtptech.com

GTP Technology offers custom protein expression

services, in multiple expression systems, to accelerate

recombinant proteins – related projects. Our services

address the needs of biopharmaceutical fi rms, diag-

nostic companies and academic research laboratories,

involved in identifying and producing target proteins,

therapeutic proteins, vaccines, disease biomarkers and

reagent proteins.

Gyros11 Deer Park Drive, Suite 100Monmouth Junction, NJ 08852 USAwww.gyros.com

Gyros™ develops and markets nano-scale immunoas-

says for bioanalytics, including assays for toxicology,

drug metabolism, biomarkers, titer and impurities. Its’

Gyrolab™ platform is based on proprietary compact

disc (CD) technology, enabling miniaturization in

nanoliter volumes and workfl ow automation for reac-

tion times in minutes. Nano-scale innovation provides

assays exhibiting wide dynamic ranges, minimal

matrix interference, throughput and effi ciencies in time

and personnel.

Malvern Instruments Ltd Enigma Business Park, Grovewood Road, Malvern, Worcestershire WR14 1XZ, UKwww.malvern.com

Malvern Instruments is a market leader in measuring

performance controlling material properties supplying

complementary materials characterization systems

which deliver inter-related measurements. Particle

size, particle shape, zeta potential, molecular weight,

chemical composition and rheological proper-

ties measurements are now joined by advanced

chromatography solutions (GPC/SEC), extending the

technologies for protein molecular weight, size and

aggregation.

MedImmuneOne MedImmune WayGaithersburg, MD 20878 USAwww.medimmune.com

MedImmune is a leading innovation-focused

biotechnology company whose mission is to provide

better medicines to patients, new medical options

for physicians and rewarding careers to employees.

Dedicated to advancing science and medicine to help

people live better lives, the company is focused on

infection, oncology, respiratory disease and infl am-

mation, cardiovascular/gastrointestinal disease and

neuroscience.

Precision Antibody™9130 Red Branch Road, Suite UColumbia, MD 21045www.precisionantibody.com

Precision Antibody provides customized, high-affi nity

monoclonal antibodies. The company’s services

are based on a proprietary antibody discovery and

development platform technology that enables rapid

development of target-specifi c, high-affi nity antibod-

ies. Precision Antibody provides one-stop service

for antibody development, characterization (affi nity

determination by Biacore), purifi cation/production

(from pilot to large scale), and conjugation, as well as

hybridoma cell banking.

ProtAffi n Biotechnologie AG Impulszentrum Graz W , Reininghausstrasse 13a Graz, A-8020 , Austria www.protaffi n.com

ProtAffi n AG is a biotechnology company developing

a novel class of biopharmaceutical products that act

by targeting cell-surface glycan structures. ProtAffi n’s

products are fi rst-in-class engineered versions of

human proteins which bind to cell surface glycans

(sugars) to affect their biological activity. Activated

versions of specifi c cell surface glycans underlie

infl ammatory processes in several diseases including

rheumatoid arthritis, chronic obstructive pulmonary

disorder, Crohn’s disease and cancer and represent a

rich and relatively under-investigated class of potential

drug targets for the pharmaceutical and biotechnology

industries.

Parkring 18Grambach, Austria A-8074www.vtu.com

VTU Technology offers services with its exclusive

cutting-edge Pichia pastoris protein production

platform. VTU´s technology is best suited for biologics

production furnishing titers of >10 g/L of secreted

target proteins.


Organized & Managed by:Cambridge Healthtech Institute250 First Avenue, Suite 300Needham, Massachusetts 02494, USA

MolecularDiagnosticsEU.com

Moving Molecular Diagnostics from Bench to Bedside5 - 6 October

NGS: The Ultimate forMolecular Diagnostics5 - 6 October

Point-of-Care Diagnostics6 - 7 October

Premier Sponsors: Corporate Sponsors:

MOLECULAR DIAGNOSTICSCambridge Healthtech Institute’s Inaugural 5 - 7 October 2010

EUROPEExhibition Grounds � Hannover, Germany

Keynote SpeakersLinh Hoang, M.D., Ph.D., LIFE TechnologiesMarjolein Kriek, M.D., Ph.D., Leiden University Medical CenterStephen Little, Ph.D., QIAGENRudi Pauwels, Ph.D., BiocartisRosanna W. Peeling, Ph.D., London School of Hygiene and Tropical Medicine

Europe’s No.1 Event in Biotechnology and Life Sciences

Held in Conjunction with

Innovation Value Discovery

MolecularDiagnosticsEU.com M-22

Please note: Video and/or audio recording of


CONFERENCE-AT-A-GLANCE

Monday, 4 October

8:20-9:30 Pre-Conference Short Course Registration (separate registrations required) Convention Center in front of Room 1

9:30-13:00 Short Course 3: Micro- and Nanofluidics in Diagnostics and Life Sciences: Technologies and Applications Location: Room Berlin

14:00-17:00 Short Course 1: Creating Synergy – Introduction to Biomedical Data Fusion Location: Room Dresden

14:00-17:00 Short Course 2: What are the Key Trends in Microfluidics for the Next 5 Years? Location: Room Berlin


18:30 Biotechnica Opening and European Award Ceremony plus Reception Location: Room 1

Tuesday, 5 October

9:00-9:30 Registration and Morning Coffee

9:30-10:35 Cancer: Molecular Biomarkers for Clinical Value Room Dresden Infectious Disease: Sequencing Microbes to Metagenomes Room Berlin


11:00-12:30 Cancer: Molecular Biomarkers for Clinical Value (cont.) Room Dresden Infectious Disease: Sequencing Microbes to Metagenomes (cont.) Room Berlin

12:30-14:20 Exhibit & Poster Viewing. Lunch for purchase at Catering Area in Exhibit Hall 9. Visit the Cambridge Healthtech Institute (CHI) Pavilion across from Catering. iPod® raffle daily at 13:30 at CHI’s Pavilion. To enter, drop off business card at CHI’s Registration Desk or exhibit booth.

14:30-15:35 Infectious Disease: Rapid Detection Strategies Room Dresden Cancer: Deep Sequencing for Genomic Rearrangements Room Berlin


16:00-18:15 Infectious Disease: Rapid Detection Strategies (cont.) Room Dresden Cancer: Deep Sequencing for Genomic Rearrangement (cont.) Room Berlin

18:15-19:15 Interactive Breakout Discussion Groups Room Bonn Interactive Breakout Discussion Groups Room Bonn


Wednesday, 6 October

9:30-10:35 Plenary Keynotes – The Future of Molecular Diagnostics Room Bonn Plenary Keynotes – The Future of Molecular Diagnostics Room Bonn


11:00-12:30 Plenary Keynotes (continued) Room Bonn Plenary Keynotes (continued) Room Bonn


13:45 Close of Conference Close of Conference

13:00-14:00 Conference Registration

14:00-15:35 Overview and Keynote Presentation Room Dresden


16:30-17:30 Point-of-Care in Clinical Settings Room Dresden


Thursday, 7 October

9:30-10:35 Amplification, Detection & Readout Technologies Room Dresden


11:30-12:30 Amplification, Detection and Readout Technologies (continued) Room Dresden


14:30-15:35 Enabling Technologies for Diagnostics Room Dresden


16:00-16:30 Standards for System Integration Room Dresden

16:30-17:30 Uptake of Point-of-Care Devices Panel Room Dresden













DataRoom 14











Room Bonn







Track 3 Room 13/14

Track 4 Room 15/16











TUESDAY, 5 OCTOBER (Morning Sessions)Moving Molecular Diagnostics from Bench to Bedside “SAMPLE IN - ANSWER OUT” DIAGNOSTIC SYSTEMS

Location: Room Dresden

NGS: The Ultimate for Molecular DiagnosticsMEDICAL SEQUENCING AND MUTATION DISCOVERY

Location: Room Berlin

Track 1 Track 2

INFECTIOUS DISEASE: SEQUENCING MICROBES TO METAGENOMES ENABLES

DIAGNOSTICS TO PROGNOSTICS

9:30 Chairperson’s RemarksStefan Niemann, Ph.D., Head, Molecular Mycobacte-riology, National Reference Center for Mycobacteria, Research Center Borstel, Germany

9:35 Next-Generation Sequencing in the Analysis of Polymicrobial Infections: Some Essential Considerations

Geraint Rogers, Ph.D., Pharmaceutical Science, King’s College London, UK

10:05 Comparative Genomics to Understand the Population Structure and Evolution of the Major Human Pathogen Mycobacterium Tuberculosis

Stefan Niemann, Ph.D., Head, Molecular Mycobacteriology, National Reference Center for Mycobacteria, Research Center Borstel, Germany

11:00 The Human Intestinal Metagenome

S. Dusko Ehrlich, Ph.D., Research Director and MetaHIT Coordinator, Department of Microbiology and Food Chain (MICA), INRA, France

11:30 Novel Diagnostic Opportunities for Oral Health through Application of NGS

Bart Keijser, Ph.D., Principal Investigator, Microbial Genomics, TNO, NL

12:00 Agilent Technologies’ SureSelect Platform: Flexible High Performance Target Enrichment System for Next-Gen Sequencing

Angelica Giuffre, R&D Scientist III, Genomics Division, Agilent Technologies

Sponsored by


CANCER: MOLECULAR BIOMARKERS FOR CLINICAL VALUE

9:30 Chairperson’s Remarks

Mark Bradley, Ph.D., Professor, Chemical Biology, University of Edinburgh, UK

9:35 Tumor-Derived Circulating DNA as Predictive Biomarker in Oncology

Tim Ward, Ph.D., Staff Scientist, Clinical and Experimental Pharmacology, Paterson Institute for Cancer Research, University of Manchester, UK

10:05 Detecting Molecular Malignancy in Gliomas: Robust Copy Number Analysis of Chromosome 1p and 19q, CDKN2A, PTEN and EGFR (Rearrangements) Using MLPA Analysis

Judith Jeuken, Ph.D., Pathology, Nijmegen University Medical Center, The Netherlands

10:35 Coffee Break

11:00 Probes and Tools for Real Time Optical Imaging of Cancer and Infection

Mark Bradley, Ph.D., Professor, Chemical Biology, University of Edinburgh, UK

11:30 Molecular Biomarkers for Prostate Cancer Bastiaan J. de Leeuw, CEO, NovioGendix, The Netherlands

11:45 Autoantibodies as Biomarkers for Prostate Cancer Risk Assessment in Patients with Elevated PSA and Negative Biopsy

Peter Schulz-Knappe, Ph.D., CSO & Executive Vice President, Diagnostics, Protagen AG

12:00 ExiStation: A Cost Effective High Throughput qPCR System for Medium and Large Hospitals

Vincent Prezioso, Ph.D., V.P., Global Marketing, Bioneer



Sponsored by



Track 1 Track 2TUESDAY, 5 OCTOBER (Afternoon Sessions)

Moving Molecular Diagnostics from Bench to Bedside “SAMPLE IN - ANSWER OUT” DIAGNOSTIC SYSTEMS


NGS: The Ultimate for Molecular DiagnosticsMEDICAL SEQUENCING AND MUTATION DISCOVERY

Location: Room Berlin

CANCER: DEEP SEQUENCING FOR GENOMIC REARRANGEMENTS

14:30 Chairperson’s RemarksNeil Gibson, Ph.D., Team Leader, Research and Genetics, AstraZeneca, UK14:35 Systems Medicine Perspective towards

Bionetworks-Based Discovery of Biomarkers and Biologic Agents in Cancer

Dimitrios Roukos, M.D., Ph.D., Associate Professor, Surgery, Ioannina University School Medicine, Greece15:05 Highly Sensitive Detection of Genome Instability

Using Next-Generation SequencingFrancesca Ciccarelli, Ph.D., Principal Investigator, IEO, European Institute of Oncology, Italy

16:00 Understanding Genomic Variations in NGS Data

Frank Schacherer, Ph.D., COO, BIOBASE GmbH16:30 Use of Cancer-Specific Genomic

Rearrangements to Quantify Disease Burden in Plasma from Patients with Solid Tumors

Phil Stephens, Ph.D., Senior Scientist, Cancer Genome Project, Sanger Institute, UK17:00 Speaker to be Announced17:30 Deep Clonal Sequencing of Archival Tumor

Samples Increases Mutation Detection SuccessNeil Gibson, Ph.D., Team Leader, Research and Genetics, AstraZeneca, UK

Sponsored by

INFECTIOUS DISEASE: RAPID DETECTION STRATEGIES

14:30 Chairperson’s RemarksVanya Gant, M.D., Ph.D., Head of Departments of Microbiology and Infectious Diseases, University College Hospitals, NHS Foundation Trust, UK14:35 Regulatory ConsiderationsErik Vollebregt, Lawyer, Greenberg Traurig, LLP, The Netherlands15:05 A Genomic Fingerprinting Microarray for

Identification of Pathogenic BacteriaJuerg E. Frey, Ph.D., Group Leader, Molecular Diagnostics and Epidemiology, Plant Protection; Federal Department of Economic Affairs, FDEA Agroscope Changins-Wädenswil Research Station, Switzerland


16:30 Towards “Same Day” Blood Culture Pathogen Detection: It’s Here, and It’s Easy

Vanya Gant, M.D., Ph.D., Head, Microbiology and Infectious Diseases, University College Hospitals, NHS Foundation Trust, UK17:00 Speed is of the Essence - Metagenomic Analysis

of Microbes in the ClinicColin Davenport, Ph.D., Clinical Research Group, Hannover University Medical School, Germany17:30 Panel Discussion with Afternoon Speakers

18:15 Interactive Breakout Discussion Groups Location: Room Bonn

1. NGS and Data Quality for Diagnostic ApplicationsModerator to be Announced

2. Sequencing Cancer Genomes: Potential Healthcare ApplicationsPhil Stephens, Ph.D., Senior Scientist, Cancer Genome Project, Sanger Institute, United Kingdom

3. Circulating Tumor Cells and Cell Free Nucleic Acids: A Real Time Access to the Cancer GenomeTim Ward, Ph.D., Staff Scientist, Clinical and Experimental Pharmacology, Paterson Institute for Cancer Research, University of Manchester, UK

4. What Does Success Look Like for an Infectious Disease Molecular Diagnostics Test, and Which of the Following Factors Drive This?Vanya Gant, M.D., Ph.D., Head of Departments of Microbiology and Infectious Diseases, University College Hospitals, NHS Foundation Trust, UK

5. High-Throughput Protein Detection Technologies in Molecular Diagnostics of CancerCristiana Tanase M.D., Ph.D., Head, Biochemistry Proteomics, Victor Babes National Institute of Pathology, Romania

6. NGS: Opportunities for Improving Oral Care Diagnostics: Translating Research to PracticeBart Keijser, Ph.D., Principal Investigator, Microbial Genomics, TNO, The Netherlands



Sponsored by


Track 1 Track 2


Moving Molecular Diagnostics from Bench to Bedside “SAMPLE IN - ANSWER OUT” DIAGNOSTIC SYSTEMS

Location: Room Bonn

NGS: The Ultimate for Molecular DiagnosticsMEDICAL SEQUENCIN AND MUTATION DISCOVERY

Location: Room Bonn

13:45 Close of Conference13:45 Close of Conference


PLENARY KEYNOTES – THE FUTURE OF MOLECULAR DIAGNOSTICS CONNECTING SCIENCE AND BUSINESS FOR CLINICAL IMPACT

9:30 Chairperson’s RemarksKevin Davies, Ph.D., Editor-in-Chief, Bio-IT World

9:35 Applications of Next-Generation Sequencing in an Academic Medical Hospital: From Single Molecules to a Complete Female Genome Marjolein Kriek, M.D., Ph.D., Clinical Geneticist, Human & Clinical Genetics, Leiden University Medical Center, The Netherlands

10:05 Drivers, Challenges and Opportunities to Bring Diagnostics Closer to the Points of Need Rudi Pauwels, Ph.D., Founding Director & CEO, Biocartis

10:35 Coffee Break

11:00 Pioneering Personalized Healthcare through Pharma Partnering: A Case Study in Companion Diagnostic Co-DevelopmentStephen Little, Ph.D., Vice President, Personalized Healthcare, QIAGEN

11:30 Bringing Next-Generation Sequencing to the ClinicLinh Hoang, M.D., Ph.D., Director, Genomic Medicine, LIFE Technologies, United States

12:00 PANEL DISCUSSION Moderator: Kevin Davies, Ph.D., Editor-in-Chief, Bio-IT WorldPanelists:




Track 3

14:00 Chairperson’s Remarks

Penny Wilson, Ph.D., Lead Specialist, Detection and Identification of Infectious Agents, Technology Strategy Board, United Kingdom

KEYNOTE PRESENTATION

14:05 Overview on POCT for Infectious Diseases: Its Promises and Challenges Rosanna W. Peeling, Ph.D., Professor, Diagnostics Research, London School of Hygiene and Tropical Medicine, Faculty of Infectious and Tropical Diseases, Department of Clinical Research

14:35 An Overview of the Diagnostics Related Programmes at NICE

Nick Crabb, Ph.D., Associate Director, Diagnostics Assessment Programme, National Institute for Health and Clinical Excellence, UK

15:05 Recombinase Polymerase Amplification: Bringing Nucleic Acid Testing to Point-of-Care

David Brooks, Ph.D., M.B.A., Business Development Manager, TwistDx Ltd.


POINT-OF-CARE IN CLINICAL SETTINGS16:30 Blood Glucose POCT in Intensive Care Unit

Patients

Hans Günther Wahl, M.D., Ph.D., Director, Institute of Lab Medicine; Professor, University Hospital, Gießen and Marburg, Department of Clinical Chemistry and Molecular Diagnostics, Germany

17:00 Implementing and Supporting POCT for Glucose, Cardiac Markers, Coagulation Parameters, Blood Gases and Ions in a Hospital Setting: Technical, Regulatory and Logistic Challenges

Viviane Van Hoof, M.D., Ph.D., Professor, Head of Department, Clinical Chemistry, University Hospital Antwerp, Belgium

17:30 Close of Day

18:30 – 21:00 BIOTECHNICA Night! Traditional Bavarian Beer Hall, dinner reception, live band playing popular music from U.S.

Location: Münchner Hall (Please register to reserve your complimentary ticket ahead of

time. No tickets will be available onsite.)


Point-of-Care DiagnosticsFROM LAB BENCH TO RAPID TESTING DEVICES



Poster Presenters

BGI ShenzhenApplication of New Generation Sequencing

Technology in Microbiology

Next Generation Sequencing to Reveal

New Sight into Cancer Research

Erasmus University Medical CentreTEMPOtest-QC - An EU FP7-Funded Project Designed

to Help Promote the Development and Use of Microbiological

(Bacterial and Fungal) Point-of-Care Testing Within Europe

Genomic Vision

The

Strength of Molecular Combing for Detecting Multiple and Complex

Rearrangements on Single DNA Molecules

Hospital de Terrassa

Personalized Oncology: Detection

of EGFR, KRAS and BRAF Mutations in Tumor Samples by High

Resolution Melting Analysis

MBio Diagnostics, Inc.

Low-Cost

System for Multiplexed Nucleic Acid Hybridization Assays

National University Hospital

The Use of Quantitative-Fluorescence Polymerase

Chain Reaction for Detection of Sex Chromosome Aneuploidies in

Singapore

Viral Loads of

Herpes Simplex Virus in Clinical Samples: A 5-Year Retrospective

Analysis

QIAGEN GmbH

Performance Characteristics of a

Pyrosequencing Assay Panel for the Identification of Key Mutations in

the Cancer-Related Genes BRAF, NRAS and EGFR

Renishaw Diagnostics Ltd.

Identification of Common Fungal Pathogens in a Single

Sample

St. Joseph’s Healthcare

Nasal Mid-Turbinate Swabs Collected in UTM or CyMol

Transport Media for Respiratory Virus Diagnosis with Molecular Assays

SurExam Bio-Tech Co. Ltd.

A Novel Liquidchip Platform for Simultaneously

Detecting 70 Alleles of DNA Somatic Mutations of EGFR, KRAS, BRAF

and PI3K from a Formalin-Fixed and Paraffin-Embedded Slide of

Tumor Tissue

University of Cambridge

Single Molecule Detection in

Fast Flow: Potential for Rapid, Ultrasensitive Diagnostic Applications



AMPLIFICATION, DETECTION AND READOUT TECHNOLOGIES9:30 Chairperson’s RemarksFrédéric Breussin, Project Manager Microfluidics, Yole Développement

9:35 Microfluidics: From the Bench to the BedsideLuc Gervais, Researcher, Point-of-Care Diagnostics, IBM Zürich Research Laboratory

10:05 Towards Diagnostics on a Single ChipChristopher J. Backhouse, Ph.D., Professor, Electrical & Computer Engineering, University of Alberta, Edmonton, Canada

10:35 Coffee Break

11:30 High-Speed, Single-Molecule Detection for Point-of-Care DiagnosticsCameron Frayling, CEO, Base4Innovation, UK

12:00 Microfluidic Technologies for Point-of-Care TestingFrédéric Breussin, Project Manager Microfluidics, Yole Développement



ENABLING TECHNOLOGIES FOR DIAGNOSTICS14:30 Chairperson’s Remarks

Gerd Michel, Ph.D., Senior Technology Officer, R&D, Foundation for Innovative New Diagnostics (FIND), Switzerland

14:35 Integrated Innovation and Point-of-Care DiagnosticsPenny Wilson, Ph.D., Lead Specialist, Detection & Identification of Infectious Agents, Technology Strategy Board, UK

15:05 Development and Implementation of Rapid Diagnostics for Developing CountriesGerd Michel, Ph.D., Senior Technology Officer, R&D, Foundation for Innovative New Diagnostics (FIND), Switzerland


STANDARDS FOR SYSTEM INTEGRATION16:00 Using VitalPAC to Integrate Point-of-Care Diagnostic Results into Clinical Pathways In Real-TimeRoger Killen, Managing Director, The Learning Clinic, UK

16:30 PANEL: UPTAKE OF POINT-OF-CARE DEVICESModerator: Penny Wilson, Ph.D., Lead Specialist, Detection & Identification of Infectious Agents, Technology Strategy Board, UK

Distinguished Panelists:Doris-Ann Williams, Director General, British In Vitro Diagnostics Association, UKNick Crabb, Ph.D., Associate Director, Diagnostics Assessment Programme, National Institute for Health and Clinical Excellence, UKRosanna W. Peeling, Ph.D., Professor, Diagnostics Research, London School of Hygiene and Tropical Medicine, Faculty of

Infectious and Tropical Diseases, Department of Clinical ResearchGerd Michel, Ph.D., Senior Technology Officer, R&D, Foundation for Innovative New Diagnostics (FIND), Switzerland


THURSDAY, 7 OCTOBER (Morning and Afternoon Sessions)Track 3

Point-of-Care DiagnosticsFROM LAB BENCH TO RAPID TESTING DEVICES



Track 1 Track 2

Agilent Technologies2850 Centerville RoadWilmington, DE 19808 USA800.227.9770/www.chem.agilent.com

Agilent Technologies is a leading global supplier

of life science instrumentation and reagents.

From sample preparation to data analysis, Agilent

Technologies provides microarrays, reagents and a

QPCR platform for multiple genomic applications,

along with the new SureSelect Target Enrichment

Platform for next-gen sequencing.

Applied Biosystems Inc./ Life Technologieswww.appliedbiosystems.com

The Applied Biosystems brand is a global leader in

providing innovative, optimized instrument systems

and workflows to accelerate academic and clinical

research, drug discovery and development, patho-

gen detection and forensic DNA analysis. Through

its Applied Biosystems and Invitrogen brand of

reagents, kits and bench-top devices, Life Tech-

nologies markets the most comprehensive portfolio

of solutions for molecular and cell biology. Life

Technologies (www.lifetech.com) is a global bio-

technology tools company dedicated to improving

the human condition. Our systems, consumables

and services enable researchers to accelerate

scientific exploration, driving to discoveries and

developments that make life even better.

BIOBASE GmbHHalchtersche Strasse 33D-38304 Wolfenbuettel, Germany

49 5331 8584 0/www.biobase-international.com

BIOBASE now offers Genome TraxTM for Next

Generation Sequencing analysis, featuring

annotations such as disease-causing mutations

and regulatory sites, mapped to genomic

coordinates. BIOBASE is a leading provider of

biological databases including the Human Gene

Mutation Database (HGMD®), TRANSFAC® and

PROTEOME™.Our mission is to help researchers

answer biological questions.

Bioneer, Inc.1000 Atlantic Avenue, Suite 102Alameda, CA 94501-1147 USAhttp://us.bioneer.com

Bioneer provides value with cost effective solu-

tions for the global healthcare market. Bioneer

offers Molecular Diagnostics instruments and

reagents, state-of-the-art RNAi therapeutics and

in-vivo SAMiRNA delivery systems. Additionally,

Bioneer has a broad portfolio in molecular biology,

DNA/RNA-synthesis, nano-biotechnology, PCR and

automation. Bioneer is a public company listed on

the KOSDAQ.

QIAGEN GmbHQIAGEN Strasse 140724 Hilden, Germanywww.qiagen.com

QIAGEN acquired DxS, in September 2009 to

create a Center of Excellence in Companion

Diagnostics. QIAGEN work with pharmaceutical

companies to support development of targeted

cancer therapies by providing biomarkers and

companion diagnostics. QIAGEN‘s product portfolio

includes real-time PCR and Pyrosequencing assays

for K-RAS to identify colorectal cancer patients

more likely to benefit from anti-EGFR therapies

such as panitumumab and cetuximab, EGFR to aid

doctors in selecting lung cancer patients suitable

for treatment with tyrosine kinase inhibitors,

B-RAF and PI3K genes among others.


Sponsor DescriptionsMOLECULAR DIAGNOSTICS

EUROPE

About Cambridge Healthtech Institute - Your Life Science Network

Founded in 1992, Cambridge

Healthtech Institute (CHI)

strives to develop quality

information sources that provide

valuable new insights and competing points

of view while offering balanced coverage of

the latest developments in the life sciences

industry. Basic research related to

commercial implications is covered, with

heavy emphasis placed on end-user insights

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coverage of the strategy behind the business.

Cambridge Healthtech Institute (CHI)

is the preeminent life science network for

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from top pharmaceutical, biotech, and

academic organizations. CHI’s integrated

portfolio of products and services includes

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sultants, Cambridge Meeting Planners, and

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includes numerous eNewsletters, Bio-IT

World magazine, as well as Lead Generation

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For a comprehensive listing and detailed

information, visit the following web sites:

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ABOUT BIOTECHNICA

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gathering for biotechnology and life sciences,

staged annually in Hannover, Germany. Due

to last year’s success we feature again a joint

days the exhibition halls, the conference rooms

and the partnering meeting boxes will be alive

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all over the world, together with investors and

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and politics - all here to discuss the latest

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Reduce time and cost by making BIO-

You can close deals, find business or research

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details at www.biotechnica.de.

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Tel. +49 511 89-31152

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