DAFTAR ISI

Halaman

HALAMAN JUDUL....................................................................................... i

HALAMAN PENGESAHAN........................................................................ ii

HALAMAN PERSETUJUAN PENGUJI .................................................... iii

ABSTRAK....................................................................................................... iv

ABSTRACT..................................................................................................... v

KATA PENGANTAR ................................................................................... vi

DAFTAR ISI................................................................................................... viii

DAFTAR TABEL........................................................................................... xi

DAFTAR GAMBAR...................................................................................... xii

DAFTAR LAMPIRAN................................................................................... xv

I. PENDAHULUAN.................................................................................... 1

1.1. Latar Belakang Masalah................................................................... 1

1.2. Rumusan Masalah............................................................................ 3

1.3. Tujuan Penelitian............................................................................. 4

1.4. Hipotesis.................................................................................. 4

1.5. Manfaat Penelitian........................................................................... 4

II. TINJAUAN PUSTAKA.......................................................................... 5

2.1. Tanaman Lamtoro (Leucaena leucochepala).................................. 5

2.1.1. Morfologi Tanaman Lamtoro (Leucaena leucochepala).... 5

2.1.2. Klasifikasi…………………………………………………. 6

2.1.3. Kandungan Kimia Tanaman Lamtoro

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(Leucaena leucochepala)..................................................... 7

2.1.4 Manfaat Tanaman Lamtoro(Leucaena leucochepala) ....... 8

2.2. Hamster (Mesocricetus auratus)...................................................... 10

2.2.1. Habitat.................................................................................. 10

2.2.2. Klasifikasi Hamster (Mesocricetus auratus)…………………. 10

2.2.3. Reproduksi Hamster (Mesocricetus auratus)………………… 12

2.2.4. Data Biologis Hamster (Mesocricetus auratus)…………… 13

2.2.5. Makanan Hamster (Mesocricetus auratus).......................... 14

2.2.6. Kandang Hamster (Mesocricetus auratus)........................... 15

2.3 Luka .............................................................................................. 16

2.3.1 Definisi Luka......................................................................... 16

2.3.2 Jenis-Jenis Luka.................................................................... 17

2.3.3 Faktor Yang Mempengaruhi Kesembuhan Luka…………. 19

2.3.4 Mekanisme Luka.................................................................. 22

2.3.5 Fase Penyembuhan Luka...................................................... 24

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2.3.6 Penanganan Medis Dalam Penyembuhan Luka................... 27

2.4 Pasta………………………………………………………………. 29

2.5 Salep................................................................................................. 30

2.5.1 Definisi Salep....................................................................... 30

2.5.2 Macam-Macam Salep........................................................... 30

2.5.3 Komposisi Salep.................................................................. 32

2.5.4 Klasifikasi vehikulum salep………………………………. 33

2.6 Ekstraksi ......................................................................................... 38

2.6.1 Ekstraksi............................................................................... 38

2.6.2 Metode Ekstraksi.................................................................. 38

III. MATERI DAN METODOLOGI PENELITIAN.................................. 41

3.1 Lokasi dan Waktu Penelitian............................................................ 41

3.2 Materi Penelitian............................................................................. 41

3.2.1 Alat Dan Bahan....................................................................... 41

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3.2..2 Subyek Penelitian................................................................... 41

3.2.3 Sampel Penelitian.................................................................. 42

3.3 Metode Penelitian............................................................................. 42

3.3.1 Rancangan / Jenis Penelitian................................................ 42

3.3.2 Variabel Penelitian.............................................................. 43

3.3.3 Teknik Pembuatan Salep Ekstrak Daun Lamtoro (Leucaena

leucochepala)....................................................................... 43

3.3.4 Persiapan Hamster (Mesocricetus auratus)........................ 45

3.3.5 Perlakuan.............................................................................. 45

3.3.6 Parameter Kesembuhan Luka............................................... 46

3.4 Variabel Yang Diamati.................................................................... 48

3.5 Analisis Data.................................................................................... 48

3.6 Diagram Alur Penelitian.................................................................. 49

IV. HASIL DAN PEMBAHASAN................................................................ 50

4.1 Hasil....................................................................................................... 504.1.1 Hasil penelitian efektifitas kerja pasta dan salep ekstrak

Daun lamtoro dengan efektifitas dosis 50mg (Leucaena leucochepala) pada luka insisi baru dan lama dengan grafik.......................................................................50

4.2 Pembahasan ............................................................................................ 54

4.2.1 Pembahasan pemeriksaan perbedaan komposisi Vehikulum antara pasta dan salep ekstrak daun lamtoro

(Leucaena leucochepala)..................................................... 54

KESIMPULAN DAN SARAN ........................................................................ 78

DAFTAR PUSTAKA ....................................................................................... 80

LAMPIRAN ...................................................................................................... 84