20131004 spect画像作成のための基礎知識 part1 収集編...

50
Toshiba Medical Systems Corporation SPECT画像作成のための基礎知識 Part.1 (収集編) 東芝メディカルシステムズ株式会社 核医学システム営業部

Upload: vonhi

Post on 30-Jun-2018

230 views

Category:

Documents


1 download

TRANSCRIPT

  • Toshiba Medical Systems Corporation

    SPECT Part.1 ()

  • Toshiba Medical Systems Corporation

    n l 1 l 2 l 3 l 4

    n l l l

    n l

    u u u

    l n

    l l

    n l l l

    2

    1

    180 90

  • Toshiba Medical Systems Corporation

    (SPECT)

  • Toshiba Medical Systems Corporation

    1

  • Toshiba Medical Systems Corporation

  • Toshiba Medical Systems Corporation

    (PMT)

    533x387mm 3PMT53 2PMT 6

    E.CAM

    3PMT (76.2mm)

    2PMT (50.8mm)

    NaI

  • Toshiba Medical Systems Corporation

    ()

    (X,Y)(Z)

    NaI

    X = Pi Wi

    Pi Z = Pi

    P1 W1:1

    P2 W2:2

    P3 W3:3

    P4 W4:4

    P5 W5:5

    P6 W6:6

    P7 W7:7

    P8 W8:8

    Pi Wi

  • Toshiba Medical Systems Corporation

    (X,Y)(Z)

    X = Pi Wi Pi

    P1

    P2

    P3 3

    P4 3

    P5 2

    P6 1

    P7 0

    P8 0

    = 1x1+2x2+3x3+3x4+2x5+1x6+0x7+0x8 1+2+3+3+2+1+0+0 = 3.5 2(X,Y)

    Pi

  • Toshiba Medical Systems Corporation

    (Scatter)

    140keV 120keV 100keV

    70keV

  • Toshiba Medical Systems Corporation

    Scatter

    Primary

    Energy

    Coun

    ts

    Photo peak

    (Primary)

  • Toshiba Medical Systems Corporation

    keV 140 133 147

    NaI10%

    (FWHM)

  • Toshiba Medical Systems Corporation

    Scatter

    Total Primary

    Energy

    Cou

    nts

    Photo peak

    1520%(Primary)(Scatter)

  • Toshiba Medical Systems Corporation

    140keV7.5% 140keV2.5%

    1min 13sec 2min 34sec

    600k counts 99mTc

    keV 140 130 150

    7.5%

    2.5%

  • Toshiba Medical Systems Corporation

    93keV 185keV 93+185keV

    93keV Scatter 185keV Scatter 93+185keV Scatter Free

  • Toshiba Medical Systems Corporation

    n l (150/170keV)l (300keV)l (400keV)l (511keV)

    n /l l l l

    n l l l l l

    AB

  • Toshiba Medical Systems Corporation

    24.1mm

    1.11mm

    0.16mm LEHR

  • Toshiba Medical Systems Corporation

  • Toshiba Medical Systems Corporation

    LEHR

    LMEGP

    10cm 20cm

  • Toshiba Medical Systems Corporation

    140KeV 360KeV 360KeV

  • Toshiba Medical Systems Corporation

    X

    LEHR LMEGP MELP

    120kV 3m

    FWHM:7.5 mm 5.5 cpm/kBq

    FWHM:10.3 mm 8 cpm/kBq

    FWHM:12.5 mm 8.4 cpm/kBq

  • Toshiba Medical Systems Corporation

    67Ga 93keV

    185keV 296keV)

  • Toshiba Medical Systems Corporation

    123I

    TOSHIBA LMEGP

    TOSHIBA LEHR

    Siemens LEHR

    123I-BMIPP

  • Toshiba Medical Systems Corporation

    ()

    n Ri Intrinsic Resolution) l

    n Rg Geometric Resolution) l l l 10cm

    n (Rs System Resolution) l () l 10cm

    n SPECT l SPECT l CenterRadialTangential3 l

  • Toshiba Medical Systems Corporation

    FWHM & FWTM

    FWHM (Full Width at Half Maximum)

    FWTM (Full Width at Tenth Maximum)

  • Toshiba Medical Systems Corporation

    FWHM

    FWHMFWHM

  • Toshiba Medical Systems Corporation

    XYZ XYZ

    2

  • Toshiba Medical Systems Corporation

    XYZ XYZ

    A B

    10cm

  • Toshiba Medical Systems Corporation

    XYZ XYZ

    10cm

  • Toshiba Medical Systems Corporation

    SPECT

    ()

    ()

  • Toshiba Medical Systems Corporation

    Rs = Ri2 + Rg2 Rs Ri Rg

    (1)Ri = 3.8mm, Rg = 6.5mm Rs = 7.5mm

    (2)

    Ri = 4.5mm, Rg = 6.5mm Rs = 7.9mm

  • Toshiba Medical Systems Corporation

    0

    2

    4

    6

    8

    10

    12

    14

    16

    18

    5 10 15 19

    (mm)

    (mmFWHM)

    LMEGPLEAPLEHR

  • Toshiba Medical Systems Corporation

    0cm 5cm 10cm 15cm 20cm 25cm 30cm 35cm

    LEHR 7.5mm FWHM@10cm

    LMEGP 10.3mm FWHM@10cm

  • Toshiba Medical Systems Corporation

    7.5mm 8.6mm

  • Toshiba Medical Systems Corporation

    SPECT

    center radial

    tangential1mm

    SPECTFWHM

  • Toshiba Medical Systems Corporation

    SPECT

    @10cm[mm] [cpm/kBq]

    A LEHR 7.4 5.5

    LMEGP 10.3 8.0

    B LEHR 7.4 5.5

    LMEGP 10.6 8.7

    C LEHR 7.4 5.4

    ELEGP 10.0 8.6

    D VXHR 7.4 3.8

    VXGP 7.8 4.2

    http://www.jsnmt.umin.ne.jp/contents/wghoukoku/standard/kikiinfo.html

  • Toshiba Medical Systems Corporation

    n SPECT1315cmSPECT912mm34mm

    n SPECT2025cmSPECT1518mm56mm

    SPECT(FWHM)1/3

  • Toshiba Medical Systems Corporation

    (SymbiaE)

    64 128 256 512 FOV

    1 9.60 4.80 2.40 1.20 533

    1.23 7.80 3.90 1.95 0.98 500

    1.45 6.62 3.31 1.66 0.83 424

    1.78 5.39 2.70 1.35 0.67 345

    2 4.80 2.40 1.20 0.60 307

    2.29 4.19 2.10 1.05 0.52 268

    2.67 3.60 1.80 0.90 0.45 230

    3.2 3.00 1.50 0.75 0.38 192

  • Toshiba Medical Systems Corporation

    SPECT

    20cm 25cm

    25

  • Toshiba Medical Systems Corporation

    (SymbiaE)

    64 128 256 512 FOV

    1 9.60 4.80 2.40 1.20 533

    1.23 7.80 3.90 1.95 0.98 500

    1.45 6.62 3.31 1.66 0.83 424

    1.78 5.39 2.70 1.35 0.67 345

    2 4.80 2.40 1.20 0.60 307

    2.29 4.19 2.10 1.05 0.52 268

    2.67 3.60 1.80 0.90 0.45 230

    3.2 3.00 1.50 0.75 0.38 192

  • Toshiba Medical Systems Corporation

    SPECT

    422mm (6.6mm)

    344mm (5.4mm)

    SPECTsmall heart

    :166cm :68kg

  • Toshiba Medical Systems Corporation

    SymbiaE

    1.23 1.45 1.78

    128128 3.9mm 3.3mm 2.7mm

    6464 7.8mm 6.6mm 5.4mm

    498mm 422mm 344mm

    SymbiaE/E.CAM6464 1.78

    ()

    5.4mm

    RI

  • Toshiba Medical Systems Corporation

    Emission & Transmission

    Transmission

    Emission

  • Toshiba Medical Systems Corporation

    180360

    180 360

    J Nuci Med 23: 661, 1982

  • Toshiba Medical Systems Corporation

    A1 A2

    B1 B2

    360 180A1/A2 1.00 1.09 B1/B2 1.01 1.21

    Tc-99m 360 180A1/A2 1.03 1.12 B1/B2 1.02 1.27

    Tl-201 20cm 360180

    180SPECT acquisition is generally preferred for both 201Tl and 99mTc protocols because of the higher contrast and resolution of the reconstructed images and greater patient throughput, although the use of 360acquisition has been advocated on the basis of its superior image uniformity and greater immunity to artifacts. Guido Germano. Technical Aspects of Myocardial SPECT Imaging. J Nucl Med.2001;42:1499-1507

    180360

  • Toshiba Medical Systems Corporation

    (180)

    44-224deg 92-272deg 136-316deg 180-360deg

  • Toshiba Medical Systems Corporation

    180360

    360 180

    RAO45

    LPO45

    LAO45

    180RAO45LAO45LPO45

  • Toshiba Medical Systems Corporation

    180360

    360 180

    180

  • Toshiba Medical Systems Corporation

    180360

    360 180

    11

    360

  • Toshiba Medical Systems Corporation

    180360 ()

    Kenichi Nakajima, et al. Ann Nucl Med (2007) 21:505511

  • Toshiba Medical Systems Corporation