[(2.1)]

1111 1111 () () . ( , , ) () ( , , , ) . , 1 ( ) , ( ) ( ) 30 , (). 30 . 1 , +1% . , 1 .2222 1 15 () . 1 , . , 1 .3333 . , ()

, . , , , , , , . 1 [( ) 2 10 ] 3 . 2 , 1 .1. , () () 2. , () () 2 , .4444 1 2.1. 1 (1 ) .2. 2 1 . 1 () , 12() .5555 .1. () ( )

.2. () .3. ( ) .6666 .1. () 2. 15 , () () () 7777 . () .1. 2. 3. 4. ()5. 1 1 . 1 3 , 26() 1 . 1 4 () () .8888 .

.9999 . .11110000 , 26() 1 .11111111 () 21( ) .11112222 () ., 6( ) 2 . 1 () 6 6 1 , .2222 (((( ))))11113333 1111 1 ( , ) . 1 1 . ( 1 , ) 1

. 2 .1. 30( ) 2. 29( ) () () . 1 2 21( ) 2 [, 18(" " ) ] 90 ( ) , .11114444 2222 2 ( ) , . , ( ) .11115555 16[ () ] () , 40() 1 . 1 ( ) . 1 2 1 1 . ()

1 26()1 .11116666 (((()))) 2 () , 3 () () () . () . 1 , 3 () 1 . , () 15 1 () . 2 [ () ] () () () () 15 () . 1 .11117777 (((()))) 16[ () ] 2 () , () . 1 () 1( ) 2 4, 13(1 ), 29( ), 30( ) 31( ) . , () 1 () .

3333 (((( ))))11118888 4( ) , , , , , , .11119999 5( ) , , ,5 .22220000 3 5 (, ) ( ) .22221111 () () (1 ) .1. () () (3 ) (2 , ) 80% : 2. () 1 : (, 1 )

22222222 () (3 ) 50% 80% ()1 21( ) 2 . 21( ) 1 () () , , 27( ) 2 . 21( ) 2 , . () 90 . . 4 . 1 21( ) 1 180 180 . , (3 ) . 6 ( 2 ) () . 1 21( ) . 1 21( ) (3 ) ,

. 1 21( ) ( ) 5 20% . 1 21( ) . , (3) . 11 (3 ) . , (3 ) .22223333 , () .1. () , () [() ()] 2 (3 ) 80% .2. () () , () .3. () 1 .1. 1 1 .2. 1 2 .3. 1 3 .

22224444,,,, () , , .22225555 1 ( 3.0% ) . , 1 . 1 1 . , . 1 . 1 3 .22226666 . 25( ) . .22227777 .22228888 , 2 .4444

22229999 () ( ) ( , ). 3() .33330000 () 29( ) . .1. 2. 1 2( 1) 3. () ( ) ( () )4. ( ) () 1 , , , . 1 . 1 , , . , () ( )

. 29( ) 1 .33331111 2( 1) 110( ) . () , 5 ( 1 ) .5555 33332222 . 1 .33333333 (((()))) () () () , () () .33334444 () 2 1 . () . ()

() 1 () . 2 () .33335555 () () 21( ) .33336666 () , .1. ()2. [, , (), , ( ) ]3. ( , )4. () 1 2 3() .33337777 36( ) , 3 . , 10 . , () () 30( ) 1 , . , . 1 ,

() , , ( ) , () , . , () () 3 3 . 3 3() , . 1 3 , , () () , ( ) () . 1 6( ) . ,4 , () () , . 1 , () () , () .33338888 [ ()] 21( ) 1 . 1 , .

33339999 () , 23( ) 12( ) .1. () , 2. , , , 3. 4. () 44440000 ( ) . . 1 , . 16[ () ] .6666 44441111 .44442222 . , .44443333 . .

44444444 ( ) ( ) .44445555 , .44446666 .44447777 .

(1) 1. 1 2 80 80 80 1.12 4( ) .2. () 12() .2. - 1(50%), 2(80%) ( 21 1) () () (3 ) 80%

1 : 50% + 2 : 20% + 1 : 100% + 2 : 100% +

( 21 2) () 1 1 : 50% 2 : 80%(, 1 ) 1. [()] 90 . , 18(" " ) .2. () (3 ) 80% .3. () (3 ) 50% 80% () 1 .4. , , .5. 5( ) , .

(2) 1. . (S00Y84) 2 1 1 2. . - (X50)- (X52)- (X53)- (X54)- (X57)- (X60X84)- (Y35.5) (Y60Y69) [, (Y83Y84) ] (X30X39) (W65W74), (W75W84), (W44) ( ) 4 ( 2002-1, 2003.1.1 ) , 5 1 2 .

(3)

(4) .... ((((CCCCrrrriiiittttiiiiccccaaaallll CCCCaaaannnncccceeeerrrr)))) , .1. . ~ . .(melanoma) (Breslow 1.5mm ) .( modified Jewett stage B0 1992 TNM T1c ).[ (papillary cancer) (follicular cancer) 2.0cm ].(HIV) (, HIV ).(melanoma) (C44). 2. (premalignant condition or condition with malignantpotential), (carcinoma in-situ) 3. , (fixed tissue), (fine needleaspiration biopsy) (hemic system) . . () ..... ((((CCCCrrrriiiittttiiiiccccaaaallll AAAAccccuuuutttteeee MMMMyyyyooooccccaaaarrrrddddiiiiaaaallll IIIInnnnffffaaaarrrrccccttttiiiioooonnnn)))) 2 .. (ST, T, Q) .CK-MB (, TROPONIN ) , , .

.... ((((CCCCrrrriiiittttiiiiccccaaaallll SSSSttttrrrrooookkkkeeee)))) , , . 1 , (symptom) (sign) 3 25% [ 13. . 1) . 1) , ] . (Brain CT Scan), (MRI), , (PET scan), (SPECT), . (transcient ischemic attack), (reversibleischemic neurological deficit) . , , . . . . (ophthalmic artery) .... ((((EEEEnnnndddd SSSSttttaaaaggggeeee RRRReeeennnnaaaallll DDDDiiiisssseeeeaaaasssseeee)))) (End Stage Renal disease) ..... " " 20% 3 . "The Rule of 9", "Lund & Browder Body Surface Chart" . , . " " .

.... . 3.0mg/ .. .. , , ( ) 1 . " " ..... .. 1 (FEV1.0) 30% . (ABGA) (PaO2) 60Hg , . X , , , .

(5) .... ((((CCCCoooorrrroooonnnnaaaarrrryyyy AAAArrrrtttteeeerrrryyyy BBBByyyyppppaaaassssssss GGGGrrrraaaafffftttt,,,, CCCCAAAABBBBGGGG)))) (Coronary Artery Disease) (greater saphenous vein), (internal mammary artery) () . .)(Percutaneous Transluminal Coronary Angioplasty, PTCA), (Coronary Stent), (Rotational atherectomy).... ((((AAAAoooorrrrttttaaaa GGGGrrrraaaafffftttt SSSSuuuurrrrggggeeeerrrryyyy)))) (excision) (graft) . (branch) . , .)(percutaneous endovascular aneurysm repair).... .. . (valvuloplasty) .. ) (percutaneous balloon valvuloplasty). .... 5555((((5555 MMMMaaaajjjjoooorrrr OOOOrrrrggggaaaannnn TTTTrrrraaaannnnssssppppllllaaaannnnttttaaaattttiiiioooonnnn))))5 5 , , , , . , .

(6) ((((33337777 5555 )))) , (21 1 2) (26 1) 1 : 50%1 : 1% +1% 1. (28) .2. .