3-y-f1-1 oral administration of food-derived amino acid ...ryuichi kambayashi 1, yoshio nunoi, ai...

3-Y-F1-1

Oral administration of food-derived amino acid ergothioneine enhanceslearning and memory by phosphorylation of TrkB and promotion ofneurogenesis in the hippocampal dentate gyrus

Yusuke Matsuo1, Takahiro Ishimoto1, Shunsuke Nakao1, Yusuke Masuo1, Satoshi Matsumoto2,Makoto Suzuki2, Yukio Kato1

1Fac. Pharm., Kanazawa Univ., 2L•S Corporation Co. Ltd.

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Copyright © The Japanese Pharmacological Society

3-Y-F1-2

The effects of Ninjinyoeto on spatial memory impairment in a rat model withcerebral ischemia and β-amyloid injection

Masaki Nagao1, Akinobu Hatae2, Kazuma Mine2, Soichiro Tsutsumi2, Marika Hiarata2,Kazuma Matsui2, Hiroya Omori2, Takuya Watanabe1,2, Kaori Kubota1,2, Shutaro Katsurabayashi2,Katsunori Iwasaki1,2

1Ins. Aging and Brain Sci., Fukuoka Univ., Fukuoka, Japan, 2Dept. Neuropharmacol. Fac. Pharm. Sci. FukuokaUniv. Fukuoka, Japan

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3-Y-F1-3

The mice with exonic Reln deletion show cognitive dysfunction but notattention impairment in the touchscreen operant tasks

Geyao Dong1, Taku Nagai1, Jingzhu Liao1, Daisuke Mori2, Bolati Wolar1, Toshitaka Nabeshima3,4,Norio Ozaki2, Kiyofumi Yamada1

1Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School ofMedicine, 2Department of Psychiatry, Nagoya University Graduate School of Medicine, 3Advanced DiagnosticSystem Research Laboratory Fujita Health University, Graduate School of Health Sciences, 4Aino University

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3-Y-F1-4

The role of voltage-dependent potassium channels in the medial prefrontalcortex in nicotine-induced enhancement of object recognition memory

Esaki Hirohito1, Shoma Izumi1, Akari Fukao2, Masaki Domoto1, Tong Zhang1, Naoya Nishitani1,2,Satoshi Deyama1,2, Katsuyuki Kaneda1,2

1Lab. Mol. Pharmacol., Inst. Med., Pharmaceut., Health Sci., Kanazawa Univ., 2Lab. Mol. Pharmacol., Sch.Pharmaceut. Sci., Kanazawa Univ.

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3-Y-F2-1

Anti-high mobility group box-1 (HMGB1) antibody therapy for spinal cordischemia-reperfusion injury in rabbits

Muraoka Genya1, Keyue Liu2, Handong Qiao2, Daiki Ousaka2, Dengli Wang2, Yasuhiro Fujii1,Shingo Kasahara1, Masahiro Nishibori2

1Dept. Cardiovascular Surg., Okayama Univ., 2Dept. Pharmacol., Okayama Univ.

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3-Y-F2-2

The identification of neuro-reparative lipids in ischemic stroke

Nakamura Akari1,2, Seiichirou Skai1, Makoto Murakami3, Takashi Shichita1,4

1Tokyo Metropolitan Inst., 2Tokyo Medical and Dental Univ.,3Tokyo Univ.,4Japan Agency for Medical Research andDevelopment

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3-Y-F2-3

TRPA1 plays a protective role in cognitive impairment and white matterinjury in chronic cerebral hypoperfusion

Masashi Kakae, Hiroki Nakajima, Misa Morishima, Shota Tobori, Kazuki Nagayasu,Hisashi Shirakawa, Shuji Kaneko

Dept. Mol. Pharmacol., Grad. Sch. Pharmaceut. Sci., Kyoto Univ.

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3-Y-F2-4

Imaging of water kinetics during cytotoxic edema using indirect MRI withO17-labeled water

Tomoe Ishikawa1, Yutaka Hoshino2, Hiroyuki Kameda2, Yuji Komaki4, Miyuki Unekawa3,Yutaka Tomita3, Jin Nakahara3, Kohsuke Kudo2, Masato Yasui1

1Dept., Pharmacol., Sch., Med., Keio Univ., 2Dept., Radiol., Hokkaido Univ Hosp., 3Dept., Neurol., Sch., Med., KeioUniv., 4Central., Inst., Exp., Anim.

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3-Y-F3-1

Development of Brain Molecular PET Imaging with a 18F-labeled SmallProtein Affinity Ligand

Takahiro Morito1, Ryuichi Harada1,2, Ren Iwata3, Yiqing Du1, Nobuyuki Okamura4,Yukitsuka Kudo2, Kazuhiko Yanai1,3

1Dept. Pharmacol., Tohoku Univ. Grad. Sch. Med.,2Dept. Gerontol. Geriatrics, Tohoku Univ.,3CYRIC, TohokuUniv., 4Div. Pharmacol., Fac. Med., Tohoku Med. Pharmaceut. Univ.

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3-Y-F3-2

Characterization of a novel monoamine oxidase-B tracer [18F]SMBT-1 forimaging of reactive astrocytes

Yiqing Du1, Ryuichi Harada1,2, Yu Akaida3, Takahiro Morito1, Hiroyuki Arai2, Mari Yoshida4,Yukitsuka Kudo2, Shozo Furumoto3, Nobuyuki Okamura5, Kazuhiko Yanai1

1Dept. Pharmacol., Grad. Sch. Med., Tohoku Univ.,2Dept. Geriatrics and Gerontology, Div. Brain Science, Inst.Development, Aging and Cancer, Tohoku Univ.,3Cyclotron and Radioisotope Ctr., Tohoku Univ.,4Inst.Development, Aging and Cancer, Aichi Medical Univ.,5Div. Pharmacol., Fac. Med., Tohoku Medical andPharmaceutical Univ.

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3-Y-F3-3

A novel method of long-lasting single-particle tracking based onregenerative fluorescent labeling

Shinkuro Kobayashi, Shigeyuki Namiki, Daisuke Asanuma, Kenzo Hirose

Dept. Pharm., Grad. Sch. Med., the Univ. of Tokyo

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3-Y-F3-4

In vivo fluorescence imaging of extracellular ATP dynamics in brainischemia

Nami Kitajima1, Kenji Takikawa1, Hiroshi Sekiya2, Daisuke Asanuma1, Hirokazu Sakamoto1,Shigeyuki Namiki1, Masamitsu Iino3, Kenzo Hirose1

1Dept. of Pharmacol., Grad. Sch. of Med., Univ. of Tokyo,2Dept. of Physiol., Grad. Sch. of Med., Univ. of Tokyo,3Dept. of Cell. and Mol. Pharmacol., Nihon Univ. Sch. of Med.

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3-Y-G1-1

Voltage-dependence in ICaL block predicts EAD in drug-induced arrhythmias

Kimura Akira1, Shingo Murakami2

1Chuo Univ. Grad. Ele., 2Chuo Univ. Grad. Sci.& Eng.

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3-Y-G1-2

Electrophysiological analysis of the anti-atrial fibrillatory action ofoseltamivir using the paroxysmal atrial fibrillation canine model

Ryuichi Kambayashi1, Yoshio Nunoi1, Ai Goto1, Yoshiki Hirokawa1, Hiroko Izumi-Nakaseko1,Mihoko Hagiwara-Nagasawa1, Yoshinori Takei2, Akio Matsumoto3, Shinichi Kawai4,Atsushi Sugiyama1,2,3,4

1Dept. Pharmacol., Faculty Med., Toho Univ.,2Dept. Translational Research & Cellular Therapeutics, FacultyMed., Toho Univ.,3Dept. Aging Pharmacol., Faculty Med., Toho Univ.,4Dept. Inflammation & Pain ControlResearch, Faculty Med., Toho Univ.

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3-Y-G1-3

Effect of hyperglycemia on the cardiovascular functions in the isoflurane-anesthetized intact dogs

Hirokawa Yoshiki1, Ryuichi Kambayashi2, Ai Goto1, Yoshio Nunoi2, Hiroko Izumi-Nakaseko1,2,Mihoko Hagiwara-Nagasawa2, Yoshinori Takei3, Akio Matsumoto4, Shinichi Kawai5, Jörg Täubel6,Atsushi Sugiyama1,2,3,4,5

1Dept. Pharmacol., Grad. Sch. Med., Toho Univ.,2Dept. Pharmacol., Faculty. Med., Toho Univ.,3Dept.Translational Research & Cellular Therapeutics., Faculty. Med., Toho Univ.,4Dept. Aging Pharmacol., Faculty.Med., Toho Univ.,5Dept. Inflammation & Pain Control Research, Faculty. Med., Toho Univ.,6Molecular & ClinicalSciences Research Institute, St George's University of London.

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3-Y-G1-4

Biological sex differences in morphological function of embryonic murinecoronary arteries

Shion Nagasawa1, Masami Kodama2, Kazuho Sakamoto1, Junko Kurokawa1

1Sch. Pharmaceut. Sci, University of Shizuoka, 2IQB, The University of Tokyo

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3-Y-G2-1

TRPC5 channel-Caveolin-1-eNOS signalplexes coordinate interplay betweenCa2+ and NO signals in endothelial cells

Reiko Sakaguchi1,2, Nobuaki Takahashi1,3, Takashi Yoshida1,4, Nozomi Ogawa1, Yoshifumi Ueda1,Satoshi Hamano1, Kaori Yamaguchi1, Seishiro Sawamura1, Shinichiro Yamamoto1,4, Yuji Hara1,Masayuki Mori1, Tetsushi Furukawa5, Shunichi Shimizu4, Ryuji Inoue6, Yasuo Mori1,2

1Department of Engineering, Kyoto Univ, 2iCeMS, Kyoto Univ, 3Hakubi Project, Kyoto Univ, 4Faculty ofPharmaceutical Sciences, Teikyo Heisei Univ,5Medical Research Institute, Tokyo Medical and Dental Univ,6Department of Physiology, Fukuoka Univ.

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3-Y-G2-2

Acute hypoxia enhances the proliferation of brain capillary endothelialcells via upregulation of Ca2+-activated Cl- channel TMEM16A.

Takahisa Suzuki1, Yoshiaki Suzuki1, Kiyohumi Asai2, Yuji Imaizumi1, Hisao Yamamura1

1Dept. Mol. and Cell. Pharmacol., Grad. Sch. Pharm., Nagoya City Univ., 2Dept. Mol. Neurobiol., Grad. Sch. Med.,Nagoya City Univ.

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3-Y-G2-3

CAMKII inhibitor as novel cardioprotective agent on doxorubicincardiotoxicity

クルニアワンプリヨノアグン, Junichiro Miake, Youkou Syuu, Katsunori Ichihara, Tatsuya Sawano,Keiko Nagata, Takeshi Imamura

Tottori University, Medical department, pharmacology

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3-Y-G2-4

Development of high efficient method in human iPS induction from patientderived primary cells.

Tanaka Naomichi, Takaaki Senbonmatsu

Saitama medical university international medical center

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3-Y-G3-1

Arginase 1 is involved in lacrimal hyposecretion in male NOD mice.

Yuta Ohno1, Keitaro Satoh1,2, Akiko Shitara1, Haruna Nagase1, Masanori Kashimata1

1Dept. Pharmacol., Asahi Univ. Sch. Dent., 2Dept. Pharmacol., Meikai Univ. Sch. Dent.

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3-Y-G3-2

Evaluation of primate dental pulp regeneration by quantitative fluorescenceimaging of macrophages

Yu Toida, Takanori Sato, Tadahiro Iimura

Dept Pharmacol, Hokkaido Univ Grad Sch Dent Med

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3-Y-G3-3

Teriparatide improves bone quality through augmenting the linearity of bonecollagen fibers, revealed by novel analysis of nonlinear optics imaging andAI-based morphometrical recognition method

Takanori Sato, Yu Toida, Tadahiro Iimura

Dept. Pharmocol. Grad. Sch. Dent Med., Hokkaido Univ.

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3-Y-G3-4

Ca2+ release-activated Ca2+ channels are involved in osteoarthritic markerinduction by interleukin-1β in mouse chondrocytes

Risa Kurose, Yoshiaki Suzuki, Yuji Imaizumi, Hisao Yamamura

Dept. Mol. Cell. Pharmacol., Grad. Sch. Pharmaceut. Sci., Nagoya City Univ.

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3-y-f1-1 oral administration of food-derived amino acid ...ryuichi kambayashi 1, yoshio nunoi, ai...

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