การบริหารจัดการโครงการวิจัยภาควิชาสูติ...

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5 5 เมษายน เมษายน 25502550

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WHY RESEARCH?WHY RESEARCH?

Higher education is best delivered in an environment where knowledge is being created

To serve our community, country, as well as globe under our capability

Number of publication in the last 10 Number of publication in the last 10 yearsyears

13

11

13

10

16

21

14

16 16

10

0

4

8

12

16

20

24

2540 2541 2542 2543 2544 2545 2546 2547 2548 2549 ป( พ.ศ.

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นวิ

นผ

ลง

าน

ติ�พ

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Source of FundingSource of Funding

สูร#ปยอดเง�นท�+ได ร�บการสูน�บสูน#นงานวิ�จั�ย10 ป(ย อนหล�ง

ทุ�นใ นคณะ ทุ�นมหาวิ ทุยาลั�ย ทุ�นใ นประ เทุศ ทุ�นต่�างประ เทุศ

Department of OB-GYNDepartment of OB-GYN

Reproductive Medicine

Maternal-fetal Medicine

Gynecologic Oncology

Publication 71 titles

Ongoing 33 projects


Ongoing 15 projects


Ongoing 25 projects

Multi-center 23 projects*

Department of OB-GYNDepartment of OB-GYN

Reproductive Medicine

Maternal-fetal Medicine

Gynecologic Oncology

Office hysteroscope Office hysteroscope (13)(13)

Prenatal Prenatal screening (18) screening (18)

Cervical cancer Cervical cancer controlcontrol

Cervical Cancer control Cervical Cancer control MappingMapping

Cervical Cancer Control

Prevention-Primary prevention

-Natural history

-Epidemiology

-Male aspect

-Educational program

-Vaccine development

-Tumor registry

Treatment-Clinical research management

-Palliative care

-Psychological support

-Clinical practice guideline

-Quality of life*

Diagnosis-Regard to etiology

• Molecular biology

• Genetic

• Immunology

• Viral study

-Screening

-Clinical practice guideline

-Diagnostic development

-Cyto-pathology

-Reference laboratory

-Test validation

-RSHPVT

Health system

Management-Referral system

-Abnormal Pap smears registration

-Cervical cancer information system

-Economic Burden of life-time treatment cost*

-Center of Cervical Cancer Control (C4)

Existing and active research

Existing but not systematically function

Research with some product

Research but still no product

Practically, non exist, need development

Research network

Revised 31 March 07

Group MeetingGroup Meeting

• Gynecologic Oncologist

• Radiotherapist

• Gynecologic Pathologist

• Cancer epidemiologist

Systematic Development of Cervical Systematic Development of Cervical Cancer Control ProjectCancer Control Project

Key indicators for quality cervical cancer management

-Preinvasive-stage

-Invasive stage

-Guideline of management of abnormal smears

Aspect of cervical cancer treatment

-prognostic factors

-Surveillance of cervical cancer patients

-Recurrent of cervical cancer

-Deep vein thrombosis in cervical cancer patients

-Investigation technique

-Chemoradiation

-Biomarker(storage of fresh tissue)

-Sentinel node

Health economic and Social research

-Public education focus on HPV vaccine era

-Attitude and knowledge of HPV and cervical cancer

-Life-time treatment cost of cervical cancer in Thailand

-Quality of life in cervical cancer patient

-Cancer information system

HPV and cervical cancer

-HPV detection and typing

-Retrospective International survey of HPV types in cervical cancer and other ano-genital cancer

Something was doneSomething was done

Guideline of management of abnormal smearsGuideline of management of abnormal smears

Development of National Research Network of Development of National Research Network of Cervical Cancer in Thailand : Phase I Cervical Cancer in Thailand : Phase I Epidemiology (TGOC)Epidemiology (TGOC)

Attitude and knowledge of HPV and Attitude and knowledge of HPV and cervical cancercervical cancer

Cancer information systemCancer information system



-Preinvasive-stage

-Invasive stage



-prognostic factors





-Chemoradiation


-Sentinel node










Something is being doneSomething is being done

Cervical cancer screening in high risk women by liquid based Cervical cancer screening in high risk women by liquid based cytology and HPV detection in ASC-US lesion.cytology and HPV detection in ASC-US lesion.

Development of National Research Network of Cervical Cancer in Development of National Research Network of Cervical Cancer in Thailand : Phase I Epidemiology (TGOC)Thailand : Phase I Epidemiology (TGOC)

Economic burden of life time treatment cost, and quality of Economic burden of life time treatment cost, and quality of life,among invasive cervical cancer patients treated at university life,among invasive cervical cancer patients treated at university hospitals, and regional cancer centers in Thailandhospitals, and regional cancer centers in Thailand

Evaluation of human papillomavirus detection and typing by MU-Evaluation of human papillomavirus detection and typing by MU-BIOTEC HPV Test compared with a standard hybrid capture 2 kid BIOTEC HPV Test compared with a standard hybrid capture 2 kid in women with ASC-USin women with ASC-US

Retrospective International Survey of HPV Typing in Cervical Retrospective International Survey of HPV Typing in Cervical cancer (RIS HPV T)cancer (RIS HPV T)

Something is being doneSomething is being done

-Expression of Survivin, P53 and Ki 67 in normal, Expression of Survivin, P53 and Ki 67 in normal, precancerouslesions and squamouscell carcinoma of uterine precancerouslesions and squamouscell carcinoma of uterine cervixcervix

-Effect of Perioperative blood transfusion during radical Effect of Perioperative blood transfusion during radical hysterectomy and pelvic lymphadenectomy on prognosis of early hysterectomy and pelvic lymphadenectomy on prognosis of early stage cervical cancer, multicenter study Thailand.stage cervical cancer, multicenter study Thailand.

-Relationship between immunohistochemistry (Survivin, MIB-1, Relationship between immunohistochemistry (Survivin, MIB-1, P53) and prognosis of cervical cancer patients treated by radical P53) and prognosis of cervical cancer patients treated by radical hysterectomy and pelvic lymphadenectomy.*hysterectomy and pelvic lymphadenectomy.*

-Prognostic significance of cyclin D1, survivin MIB1 in cervical Prognostic significance of cyclin D1, survivin MIB1 in cervical carcinoma treated with radiotherapy alone.carcinoma treated with radiotherapy alone.



-Preinvasive-stage

-Invasive stage



-prognostic factors





-Chemoradiation


-Sentinel node










Something will be doneSomething will be done

Deep vein thrombosis in cervical Deep vein thrombosis in cervical cancer patientscancer patients

Sentinel node in early stage of Sentinel node in early stage of cervical cancercervical cancer

Comparing Standard concurrent Comparing Standard concurrent Chemo-radiation to neoadjuvant Chemo-radiation to neoadjuvant chemotherapy followed by surgery or chemotherapy followed by surgery or radiation in Patients stage Ib2-IIb radiation in Patients stage Ib2-IIb cervical carcinoma : Multicenter trialscervical carcinoma : Multicenter trials

Our Ultimate GoalOur Ultimate Goal

C4 of PSU was recognized as a C4 of PSU was recognized as a center for holistic approach of center for holistic approach of cervical cancer controlcervical cancer control

Age standardized incidence Age standardized incidence rate of cervical cancer is less rate of cervical cancer is less than 10/100 000than 10/100 000

Our FutureOur Future

A self-dependent institute dedicate to A self-dependent institute dedicate to cervical cancer research for cervical cancer cervical cancer research for cervical cancer control in developing countriescontrol in developing countries

Key of successKey of success

The shortest answer is doingThe shortest answer is doing

การบริหารจัดการโครงการวิจัยภาควิชาสูติ...

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