a dielectrophoretic cell/particle separator fabricated by spiral channels and concentric gold...
Post on 19-Dec-2015
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TRANSCRIPT
A DIELECTROPHORETIC CELL/PARTICLE SEPARATOR
FABRICATED BY SPIRAL CHANNELS AND CONCENTRIC GOLD
ELECTRODES
Reporter : Meng-Hua ChungProfessor : 劉承賢教授
Outlines Introduction Design principle Simulation Fabrication Result Conclusion
Introduction Separation method:
Passive : base on geometries Advantages: implementation easy Disadvantages: performance is not very well
Active: require actuation mechanism Magnetic force Hydrodynamic force Electrical force
Introduction Magnetic force
Most materials cannot be magnetized Hydrodynamic force
Difficulty in controlling and may damage viable cell
Electrical force Electrophoresis Dielectrophoresis(DEP)
Introduction• Electrophoresis
Introduction Dielectrophoresis
Design Principle DEP force is formed by non-uniform electric field and non-zero CM factor
Design principleCrossover frequency
Design pattern
simulation
Fabrication
Result
Conclusion This spiral channels have two way to
use: Different size particles(R) Different type cells(CM factor)
This paper already test different size particles, but the result do not fit the formular .