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IMS PHYSICIAN ENGAGED PATIENT PROGRAM About QuintilesIMS CREATING SOLUTIONS FOR YOU TO DRIVE HEALTHCARE FORWARD QuintilesIMS (NYSE:Q) is a leading integrated information and technology-enabled healthcare service provider worldwide, dedicated to helping its clients improve their clinical, scientific and commercial results. Formed through the merger of Quintiles and IMS Health, QuintilesIMS’s approximately 50,000 employees conduct operations in more than 100 countries. Companies seeking to improve real-world patient outcomes and enhanced clinical trial outsourcing through treatment innovations, care provision and access can leverage QuintilesIMS’s broad range of healthcare information, technology and service solutions to drive new insights and approaches. QuintilesIMS provides solutions that span clinical to commercial bringing clients a unique opportunity to realize the full potential of innovations and advance healthcare outcomes. As a global leader in protecting individual patient privacy, QuintilesIMS uses healthcare data to deliver critical, real-world disease and treatment insights. Through a wide variety of privacy-enhancing technologies and safeguards, QuintilesIMS protects individual privacy while managing information to drive healthcare forward. These insights and execution capabilities help biotech, medical device, and pharmaceutical companies, medical researchers, government agencies, payers and other healthcare stakeholders in the development and approval of new therapies, identify unmet treatment needs and understand the safety, effectiveness and value of pharmaceutical products in improving overall health outcomes. To learn more, visit www.quintilesims.com. ©2017 QuintilesIMS and its affiliates. All rights reserved. Trademarks are registered in the United States and in various other countries. 535 Legget Drive, Tower C, 7th floor Kanata, Ontario K2K 3B8 (613) 599-0711 6700 Century Avenue, Suite 300 Mississauga, Ontario L5N 6A4 (905) 816-5000 QuintilesIMS™ 16720 Trans-Canada Highway Kirkland (Québec) H9H 5M3 (514) 428-6000 Contact us at www.quintilesims.com

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IMS PHYSICIAN ENGAGED PATIENT PROGRAM

About QuintilesIMSCREATING SOLUTIONS FOR YOU TO DRIVE HEALTHCARE FORWARD

QuintilesIMS (NYSE:Q) is a leading integrated information and technology-enabled healthcare service provider

worldwide, dedicated to helping its clients improve their clinical, scientific and commercial results. Formed

through the merger of Quintiles and IMS Health, QuintilesIMS’s approximately 50,000 employees conduct

operations in more than 100 countries. Companies seeking to improve real-world patient outcomes and

enhanced clinical trial outsourcing through treatment innovations, care provision and access can leverage

QuintilesIMS’s broad range of healthcare information, technology and service solutions to drive new insights

and approaches. QuintilesIMS provides solutions that span clinical to commercial bringing clients a unique

opportunity to realize the full potential of innovations and advance healthcare outcomes.

As a global leader in protecting individual patient privacy, QuintilesIMS uses healthcare data to deliver critical,

real-world disease and treatment insights. Through a wide variety of privacy-enhancing technologies and

safeguards, QuintilesIMS protects individual privacy while managing information to drive healthcare forward.

These insights and execution capabilities help biotech, medical device, and pharmaceutical companies, medical

researchers, government agencies, payers and other healthcare stakeholders in the development and approval

of new therapies, identify unmet treatment needs and understand the safety, effectiveness and value of

pharmaceutical products in improving overall health outcomes. To learn more, visit www.quintilesims.com.

©2017 QuintilesIMS and its affiliates. All rights reserved.

Trademarks are registered in the United States and in various other countries.

535 Legget Drive, Tower C, 7th floorKanata, Ontario K2K 3B8(613) 599-0711

6700 Century Avenue, Suite 300Mississauga, Ontario L5N 6A4(905) 816-5000

QuintilesIMS™16720 Trans-Canada Highway Kirkland (Québec) H9H 5M3 (514) 428-6000

Contact us at www.quintilesims.com

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IMS Physician Engaged Patient Program

The next generation solution for optimal communications with patients Increasingly, pharmaceutical marketing effectiveness is being improved by an enhanced understanding of the picture that emerges when direct communications are optimized with the patients who are on their drug therapy.

IMS Physician Engaged Patient Program (P.E.P.P.) was developed following extensive research into the needs of the Canadian pharmaceutical industry. P.E.P.P. links together the patient’s electronic medical record (EMR) with a state-of-the art patient communication software system, in partnership with a team of primary care physicians covering, with permission today, 500,000 Canadian patients, and with the option of extending permission to 2.2 million Canadian patients. It is the first program of its kind to enable patient communication in partnership with the patient’s general practitioner (GP).

The process is simple and is tailored to each individual program by adapting the best practice for patient intervention and building with the GP team the optimal patient journey, which is then used to drive patient communication for that program.

The patient flow through the medication options is identified with the collaboration of both the pharmaceutical company and the medical team. Patients suitable for the program are then identified based on the rules of the patient pathway, combined with published treatment protocols and KOL support. Patients identified as requiring action due to sub-optimal results from their therapy will be contacted via email from their physician. Various interventions can then be suggested based on an online survey the patient completes

electronically. Options could include a medication review with their physician, enrollment into a study, support and training on how to optimize their current treatment, or lifestyle and diet advice.

COMMUNICATE WITH PHYSICIANS AND PATIENTS VIA ONE CENTRAL TOOL, WITH ADDITIONAL ACCESS TO 2.2 MILLION PATIENTS LINKED WITH EMR VIA THEIR PHYSICIANS.

This program brings you closer to patients than ever before by delivering unparalleled insights into disease, treatment and outcomes, in addition to the cost-efficient tools for establishing dialogue. Benefits include:

• Instant access to a large pool of Canadian patients already enrolled

• Joint partnership with physicians and HCPs, not as a separate project

• Follows published protocols and guidelines or is adaptable to KOL input

• Allows access in real-time to the program to report progress whenever required

• Uses the latest cutting-edge technology to automate processes and reduce costs significantly

• Can be easily tailored to run adherence, information, surveys, training, registries or any manner of patient engagements

• Is organized and run by Canadian physicians in partnership with experts in delivering outcomes from data management

Through such developments, patients will value and appreciate the information delivered – positioning the product as the leader in its therapeutic area.

• Advanced outcomes not available elsewhere – clinical and system

• More immediate and accurate than chart audits

• More cost effective and sustainable than a clinical trial

• Gets you closer to patients than agency programs

• Central database of privacy rules adhering to pharmacovigilance processes reducing legal risks

Putting the patient at the heart of everything we do is a common theme in the pharmaceutical industry. Enabling this goal requires careful navigation of direct to consumer regulations and privacy regulations. Add this to the ever growing need to study patients in the real world once a drug is marketed, the challenge becomes greater. How to cost effectively build a relationship with patients and understand the value various medicines deliver, improve adherence and ultimately brand loyalty is why the IMS Physician Engaged Patient Program was developed. Designed with the pharmaceutical industry and physicians, it is much more than a support tool for patients. It is an interactive ongoing communication system between the pharmaceutical company, the GP and their patients.

Pharmaco patient program requirement

Patient gets email, text, survey, web invite

from their physician

Patient is recruited by their physician

into program

Dashboard showing progress and results

to pharmaco

IMS set up electronic patient journey to

follow protocol

Pharmaco / IMS agree protocol with physicians,

regulators and legal