動物を用いた研究論文

年 掲載誌等名 発行年 発行月 巻 号 開始頁 終了頁 論文等の名称 著者

2016 1 Genes Cells 2016 3Glucose-regulated protein 78 (GRP78) binds directly to PIP3phosphatase SKIP and determines its localization

Ijuin T, Hatano N, Takenawa T

2016 2Cell Rep 2016 3 14 9 2209 23

Identification of a Post-translational Modification with Ribitol-Phosphate and Its Defect in Muscular Dystrophy

Kanagawa M, Kobayashi K, Tajiri M, Manya H, Kuga A,Yamaguchi Y, Akasaka-Manya K, Furukawa J, Mizuno M,Kawakami H, Shinohara Y, Wada Y, Endo T, Toda T

2016 3 Neurosci Lett 2016 3 616 170 6Slow synaptic transmission mediated by TRPV1 channels inCA3 interneurons of the hippocampus

Eguchi N, Hishimoto A, Sora I, Mori M

2016 4 Mol Cell Neurosci 2016 3 71 25 33Activity-dependent alteration of the morphology of ahippocampal giant synapse

Maruo T, Mandai K, Takai Y, Mori M

2016 5 J Biol Chem 2016 3 291 11 5817 31A Novel Nectin-mediated Cell Adhesion Apparatus That IsImplicated in Prolactin Receptor Signaling for Mammary Gland

Kitayama M, Mizutani K, Maruoka M, Mandai K, SakakibaraS, Ueda Y, Komori T, Shimono Y, Takai Y

2016 6 Genes Cells 2016 2Essential role of Wnt5a-Ror1/Ror2 signaling in metanephricmesenchyme and ureteric bud formation

Qi X, Okinaka Y, Nishita M, Minami Y

2016 7 Int J Oncol 2016 2Transcutaneous carbon dioxide suppresses epithelial-mesenchymal transition in oral squamous cell carcinoma

Iwata E, Hasegawa T, Takeda D, Ueha T, Kawamoto T,Akisue T, Sakai Y, Komori T

2016 8 BMC Musculoskelet Disord 2016 2 17 1 83 83 Profiling microRNA expression during fracture healingWaki T, Lee SY, Niikura T, Iwakura T, Dogaki Y, OkumachiE, Oe K, Kuroda R, Kurosaka M

2016 9 J Cell Biol 2016 2 212 5 561 75Synergistic action of nectins and cadherins generates themosaic cellular pattern of the olfactory epithelium

Katsunuma S, Honda H, Shinoda T, Ishimoto Y, Miyata T,Kiyonari H, Abe T, Nibu K, Takai Y, Togashi H

2016 10 J Dermatol Sci 2016 2 81 2 129 31Identification of potassium and chloride channels in eccrinesweat glands

Cui CY, Sima J, Yin M, Michel M, Kunisada M,Schlessinger D

2016 11J Cardiol 2016 2 67 2 205 11

Stabilization of atherosclerotic plaque by pitavastatin inWatanabe heritable hyperlipidemic rabbits: A serial tissue-characterizing intravascular ultrasound study

Haruta H, Hiro T, Mitsumata M, Takayama T, Sudo M, Li Y,Takahashi R, Taniguchi Y, Shiomi M, Hirayama A

2016 12 Paediatr Anaesth 2016 1 26 1 52 9Effects of sevoflurane exposure during late pregnancy on braindevelopment of offspring mice

Suehara T, Morishita J, Ueki M, Ueno M, Maekawa N,Mizobuchi S

2016 13 Acta Biomater 2016 1 29 468 76Fabrication of a magnesium alloy with excellent ductility forbiodegradable clips

Ikeo N, Nakamura R, Naka K, Hashimoto T, Yoshida T,Urade T, Fukushima K, Yabuuchi H, Fukumoto T, Ku Y,

2016 14 J Clin Investig Dermatol 2016 1 4 1Aerosol Delivery Enhances Percutaneous Permeability ofEpidermal Growth Factor and Thioredoxin

Tian H, Fukunaga A, Yodoi J, Nishigori C

2016 15 Virology 2016 1 489 151 157 Human herpesvirus 6 U11 protein is critical for virus infectionMahmoud NF, Kawabata A, Tang H, Wakata A, Wang B,Serada S, Naka T, Mori Y

2016 16 Cereb Cortex 2016 1Dorsal Forebrain-Specific Deficiency of Reelin-Dab1 SignalCauses Behavioral Abnormalities Related to Psychiatric

Imai H, Shoji H, Ogata M, Kagawa Y, Owada Y, MiyakawaT, Sakimura K, Terashima T, Katsuyama Y

2016 17 Br J Pharmacol 2016 1Anti-oxidative effect of AST-120 on kidney injury aftermyocardial infarction

Fujii H, Yonekura Y, Yamashita Y, Kono K, Nakai K, GotoS, Sugano M, Goto S, Fujieda A, Ito Y, Nishi S

2016 18 Mol Cancer Res 2016 1 14 354 362miR-137 Regulates the Tumorigenicity of Colon Cancer StemCells Through the Inhibition of DCLK1

Sakaguchi M, Hisamori S, Oshima N, Sato F, Shimono Y,Sakai Y

2016 19 J Diabetes Investig 2016 1 7 1 27 8A novel role for the cell cycle regulatory complex cyclin D1-CDK4 in gluconeogenesis

Hosooka T, Ogawa W

2016 20Genes Cells 2016 1 21 1 88 98

Regulatory role of the cell adhesion molecule nectin-1 inGABAergic inhibitory synaptic transmission in the CA3 regionof mouse hippocampus

Geng X, Mandai K, Maruo T, Wang S, Fujiwara T,Mizoguchi A, Takai Y, Mori M

2016 21Sci Rep 2016 1 6 18979 #####

PKN3 is the major regulator of angiogenesis and tumormetastasis in mice

Mukai H, Muramatsu A, Mashud R, Kubouchi K, TsujimotoS, Hongu T, Kanaho Y, Tsubaki M, Nishida S, Shioi G,Danno S, Mehruba M, Satoh R, Sugiura R

2016 22Metabolomics 2016 0

LC?MS/MS-based metabolome analysis detected changes inthe metabolic profiles of small and large intestinaladenomatous polyps in Apc Min/+ mice

Makoto Suzuki, Shin Nishiumi, Takashi Kobayashi, TakeshiAzuma, Masaru Yoshida

2016 23Brain 2016 0 139 ## 242 258

Frontal white matter hyperintensities, clasmatodendrosis andgliovascular abnormalities in ageing and post-stroke dementia

Chen A, Akinyemi RO, Hase Y, Firbank MJ, Foster V,Craggs L, Washida K, Okamoto Y, Thomas AJ, PolvikoskiTM, Allan LM, Oakley AE, O;Brien JT, Horsburgh K, Ihara

2015 1 Cardiovasc Drugs Ther 2015 12 29 6 499 507The Vitamin D Receptor Activator Maxacalcitol ProvidesCardioprotective Effects in Diabetes Mellitus

Fujii H, Nakai K, Yonekura Y, Kono K, Goto S, Hirata M,Shinohara M, Nishi S, Fukagawa M

2015 2Biochim Biophys Acta 2015 12 1853 12 3192 201

Regulation of insulin signaling in skeletal muscle by PIP3phosphatase, SKIP, and endoplasmic reticulum molecularchaperone glucose-regulated protein 78

Ijuin T, Hatano N, Hosooka T, Takenawa T

2015 3

Appl Radiat Isot 2015 12 106 195 201Boron neutron capture therapy (BNCT) as a new approach forclear cell sarcoma (CCS) treatment: Trial using a lungmetastasis model of CCS

Andoh T, Fujimoto T, Suzuki M, Sudo T, Sakurai Y, TanakaH, Fujita I, Fukase N, Moritake H, Sugimoto T, Sakuma T,Sasai H, Kawamoto T, Kirihata M, Fukumori Y, Akisue T,Ono K, Ichikawa H

2015 4

Appl Radiat Isot 2015 12 106 220 5Potential of boron neutron capture therapy (BNCT) formalignant peripheral nerve sheath tumors (MPNST)

Fujimoto T, Andoh T, Sudo T, Fujita I, Fukase N, TakeuchiT, Sonobe H, Inoue M, Hirose T, Sakuma T, Moritake H,Sugimoto T, Kawamoto T, Fukumori Y, Yamamoto S, AtagiS, Sakurai Y, Kurosaka M, Ono K, Ichikawa H, Suzuki M

2015 5 Eur Heart J 2015 12Intravascular fibrin molecular imaging improves the detectionof unhealed stents assessed by optical coherence tomography

Hara T, Ughi GJ, McCarthy JR, Erdem SS, Mauskapf A,Lyon SC, Fard AM, Edelman ER, Tearney GJ, Jaffer FA

2015 6 Invest Ophthalmol Vis Sci 2015 12 56 13 7839 46Subconjunctivally Implanted Hydrogels for Sustained InsulinRelease to Reduce Retinal Cell Apoptosis in Diabetic Rats

Imai H, Misra GP, Wu L, Janagam DR, Gardner TW, LoweTL

2015 7 Clin Neurol Neurosurg 2015 11 138 37 44Combined IDH1 mutation and MGMT methylation status onlong-term survival of patients with cerebral low-grade glioma

Tanaka K, Sasayama T, Mizukawa K, Takata K, SulaimanNS, Nishihara M, Kohta M, Sasaki R, Hirose T, Itoh T,

2015 8Arthritis Res Ther 2015 11 17 314 314

p21 deficiency is susceptible to osteoarthritis through STAT3phosphorylation

Hayashi S, Fujishiro T, Hashimoto S, Kanzaki N, Chinzei N,Kihara S, Takayama K, Matsumoto T, Nishida K, KurosakaM, Kuroda R

2015 9 Urology 2015 11 86 5 929 35Identification of Spermatogenically Active Regions in RatTestes by Using Narrow-band Imaging System

Enatsu N, Miyake H, Chiba K, Fujisawa M

2015 10 Vaccine 2015 11 33 45 6085 92A recombinant varicella vaccine harboring a respiratorysyncytial virus gene induces humoral immunity

Murakami K, Matsuura M, Ota M, Gomi Y, Yamanishi K,Mori Y

2015 11 Immunotherapy 2015 11 7 11 1201 11Manipulating regulatory T cells: a promising strategy to treatautoimmunity

Zhang D, Tu E, Kasagi S, Zanvit P, Chen Q, Chen W

2015 12 Mol Cell Biol 2015 11 36 3 407 20The Mediator Subunit MED16 Transduces NRF2-ActivatingSignals into Antioxidant Gene Expression

Sekine H, Okazaki K, Ota N, Shima H, Katoh Y, Suzuki N,Igarashi K, Ito M, Motohashi H, Yamamoto M

2015 13 Neurosci Lett 2015 10 606 188 93Metabolomic profiling in inner ear fluid by gaschromatography/mass spectrometry in guinea pig cochlea

Fujita T, Yamashita D, Irino Y, Kitamoto J, Fukuda Y,Inokuchi G, Hasegawa S, Otsuki N, Yoshida M, Nibu K

2015 14Mol Cell Biol 2015 10 36 1 108 18

Phosphatidylinositol 3,4,5-Trisphosphate Phosphatase SKIPLinks Endoplasmic Reticulum Stress in Skeletal Muscle toInsulin Resistance

Ijuin T, Hosooka T, Takenawa T

2015 15J Chromatogr B AnalytTechnol Biomed Life Sci

2015 10 1003 35 40Profiling of volatile compounds in APC(Min/ ) mice blood bydynamic headspace extraction and gas chromatography/mass

Kakuta S, Nishiumi S, Yoshida M, Fukusaki E, Bamba T

2015 16Target Oncol 2015 10

Acceleration of Proteinuria without Significant Impact on RenalFunction and Its Protection by Angiotensin II Receptor Blockerin Rats Treated with Axitinib

Imai S, Miyake H, Fujisawa M

2015 17 J Biosci Bioeng 2015 10 120 4 476 82Lipidomic analysis of plasma lipoprotein fractions in myocardialinfarction-prone rabbits

Takeda H, Koike T, Izumi Y, Yamada T, Yoshida M, ShiomiM, Fukusaki E, Bamba T

2015 18Clin Nutr 2015 10 34 5 997 1009

Lard-based high-fat diet increases secretory leukocyteprotease inhibitor expression and attenuates the inflammatoryresponse of acute lung injury in endotoxemic rats

Fujiwara M, Miyoshi M, Sakai S, Nishiokada A, Aoyama-Ishikawa M, Maeshige N, Usami Y, Hamada Y, TakahashiM, Usami M

2015 19 Kobe J Med Sci 2015 10 61 2 E47 53Stable Somatic Gene Expression in Mouse Lungs FollowingElectroporation-mediated Tol2 Transposon Delivery

Sakti Muliawan H, Nakayama K, Yagi K, Ikeda K, Yagita K,Hirata K, Emoto N

2015 20 Neural Dev 2015 10 10 23 23The LRR receptor Islr2 is required for retinal axon routing atthe vertebrate optic chiasm

Panza P, Sitko AA, Maischein HM, Koch I, Fl?tenmeyer M,Wright GJ, Mandai K, Mason CA, S?llner C

2015 21Arthritis Res Ther 2015 9 17 253 253

Recombinant human SIRT1 protects against nutrientdeprivation-induced mitochondrial apoptosis throughautophagy induction in human intervertebral disc nucleus

Miyazaki S, Kakutani K, Yurube T, Maeno K, Takada T,Zhang Z, Kurakawa T, Terashima Y, Ito M, Ueha T,Matsushita T, Kuroda R, Kurosaka M, Nishida K

2015 22J Neurooncol 2015 9 124 2 165 74

STAT3 activation is associated with cerebrospinal fluidinterleukin-10 (IL-10) in primary central nervous systemdiffuse large B cell lymphoma

Mizowaki T, Sasayama T, Tanaka K, Mizukawa K, TakataK, Nakamizo S, Tanaka H, Nagashima H, Nishihara M,Hirose T, Itoh T, Kohmura E

2015 23 Oncotarget 2015 9 6 29 26544 5 Targeting glutaminase and mTOR Tanaka K, Sasayama T, Kohmura E

2015 24 Int J Oncol 2015 9 47 3 891 9Antitumor effect of YM155, a novel small-molecule survivinsuppressant, via mitochondrial apoptosis in human MFH/UPS

Minoda M, Kawamoto T, Ueha T, Kamata E, Morishita M,Harada R, Toda M, Onishi Y, Hara H, Kurosaka M, Akisue

2015 25 Neurosci Lett 2015 9 604 42 6Monosynaptic excitatory transmission from the hippocampalCA1 region to the subiculum

Geng X, Mori M

2015 26Biochem Biophys ResCommun

2015 9 465 3 356 62Targeted activation of endothelin-1 exacerbates hypoxia-induced pulmonary hypertension

Satwiko MG, Ikeda K, Nakayama K, Yagi K, Hocher B,Hirata K, Emoto N

2015 27 Int J Mol Sci 2015 9 16 9 22781 94 Enantioselective Pharmacokinetics of α-Lipoic Acid in Rats Uchida R, Okamoto H, Ikuta N, Terao K, Hirota T

2015 28Mol Cell Neurosci 2015 9 68 143 50

Nectin-1 spots regulate the branching of olfactory mitral celldendrites

Fujiwara T, Inoue T, Maruo T, Rikitake Y, Ieki N, Mandai K,Kimura K, Kayahara T, Wang S, Itoh Y, Sai K, Mori M, MoriK, Takai Y, Mizoguchi A

2015 29 Brain Res 2015 9 1620 139 52Impairment of radial glial scaffold-dependent neuronalmigration and formation of double cortex by genetic ablation of

Yamamoto H, Mandai K, Konno D, Maruo T, Matsuzaki F,Takai Y

2015 30Nat Commun 2015 9 6 8424 8424

Antibiotics in neonatal life increase murine susceptibility toexperimental psoriasis

Zanvit P, Konkel JE, Jiao X, Kasagi S, Zhang D, Wu R,Chia C, Ajami NJ, Smith DP, Petrosino JF, Abbatiello B,Nakatsukasa H, Chen Q, Belkaid Y, Chen ZJ, Chen W

2015 31Am J Respir Cell Mol Biol 2015 9 53 3 314 25

The Regulation of Proresolving Lipid Mediator Profiles inBaboon Pneumonia by Inhaled Carbon Monoxide

Dalli J, Kraft BD, Colas RA, Shinohara M, Fredenburgh LE,Hess DR, Chiang N, Welty-Wolf K, Choi AM, PiantadosiCA, Serhan CN

2015 32Br J Radiol 2015 9 88 ## ###### #####

MRI study of atherosclerotic plaque progression usingultrasmall superparamagnetic iron oxide in Watanabe heritablehyperlipidemic rabbits

Kaneko C, Nitta N, Tsuchiya K, Watanabe S, Nitta-Seko A,Ohta S, Otani H, Sonoda A, Murata K, Shiomi M

2015 33 Life Sci 2015 9 136 73 8Isomeric effects of anti-diabetic α-lipoic acid with γ-cyclodextrin

Naito Y, Ikuta N, Okano A, Okamoto H, Nakata D, Terao K,Matsumoto K, Kajiwara N, Yasui H, Yoshikawa Y

2015 34Brain Pathol 2015 8

Tumor-Associated Macrophages Associate with CerebrospinalFluid Interleukin-10 and Survival in Primary Central NervousSystem Lymphoma (PCNSL)

Sasayama T, Tanaka K, Mizowaki T, Nagashima H,Nakamizo S, Tanaka H, Nishihara M, Mizukawa K, HiroseT, Itoh T, Kohmura E

2015 35

Cardiovasc Diabetol 2015 8 14 104 104

Involvement of Rho-associated protein kinase (ROCK) andbone morphogenetic protein-binding endothelial cell precursor-derived regulator (BMPER) in high glucose-increased alkalinephosphatase expression and activity in human coronary arterysmooth muscle cells

Terao Y, Satomi-Kobayashi S, Hirata K, Rikitake Y

2015 36 Bone Joint J 2015 8 97-B 8 1144 51Profiling microRNA expression in fracture nonunions: Potentialrole of microRNAs in nonunion formation studied in a rat model

Waki T, Lee SY, Niikura T, Iwakura T, Dogaki Y, OkumachiE, Kuroda R, Kurosaka M

2015 37 J Biochem 2015 8 158 2 91 9 Current status of the development of Ras inhibitorsShima F, Matsumoto S, Yoshikawa Y, Kawamura T, Isa M,Kataoka T

2015 38

Proc Natl Acad Sci U S A 2015 8 112 31 E4264 71Protein tyrosine phosphatase SAP-1 protects against colitisthrough regulation of CEACAM20 in the intestinal epithelium

Murata Y, Kotani T, Supriatna Y, Kitamura Y, Imada S,Kawahara K, Nishio M, Daniwijaya EW, Sadakata H,Kusakari S, Mori M, Kanazawa Y, Saito Y, Okawa K,Takeda-Morishita M, Okazawa H, Ohnishi H, Azuma T,

2015 39 Reproduction 2015 8 150 2 105 14Endogenous interleukin 18 regulates testicular germ cellapoptosis during endotoxemia

Inoue T, Aoyama-Ishikawa M, Kamoshida S, Nishino S,Sasano M, Oka N, Yamashita H, Kai M, Nakao A, Kotani J,

2015 40Clin Nutr 2015 8 34 4 685 93

Changes of hepatic lipid mediators associated with intake ofhigh-fat diet for 12 weeks in endotoxemic rats using LC-ESI-MS/MS

Nishiokada A, Miyoshi M, Fujiwara M, Aoyama-Ishikawa M,Maeshige N, Takahashi M, Hamada Y, Usami Y, Honda M,Arita M, Usami M

2015 41Nutr Metab (Lond) 2015 8 12 30 30

High-fructose and high-fat diet-induced insulin resistanceenhances atherosclerosis in Watanabe heritable hyperlipidemicrabbits

Ning B, Wang X, Yu Y, Waqar AB, Yu Q, Koike T, Shiomi M,Liu E, Wang Y, Fan J

2015 42Biomaterials 2015 8 60 9 19

The effect of blocking angiogenesis on anterior cruciateligament healing following stem cell transplantation

Takayama K, Kawakami Y, Mifune Y, Matsumoto T, TangY, Cummins JH, Greco N, Kuroda R, Kurosaka M, Wang B,Fu FH, Huard J

2015 43 Biochem J 2015 8 469 3 445 54Role for RalA downstream of Rac1 in skeletal muscle insulinsignalling

Takenaka N, Sumi Y, Matsuda K, Fujita J, Hosooka T,Noguchi T, Aiba A, Satoh T

2015 44 FASEB J 2015 8 29 8 3133 40Novel role for retinol-binding protein 4 in the regulation ofblood pressure

Kraus BJ, Sartoretto JL, Polak P, Hosooka T, Shiroto T,Eskurza I, Lee SA, Jiang H, Michel T, Kahn BB

2015 45J Comp Neurol 2015 8 523 12 1824 39

Nectin-1 spots as a novel adhesion apparatus that tethersmitral cell lateral dendrites in a dendritic meshwork structureof the developing mouse olfactory bulb

Inoue T, Fujiwara T, Rikitake Y, Maruo T, Mandai K,Kimura K, Kayahara T, Wang S, Itoh Y, Sai K, Mori M, MoriK, Mizoguchi A, Takai Y

2015 46 Diabetes Frontier 2015 8 264号

499 503 インスリン作用のKey Molecules　PDK1 細岡 哲也, 小川 渉

2015 47 Clin Exp Pharmacol Physiol 2015 7Anti-oxidative Effect of the β-blocker Carvedilol on DiabeticNephropathy in Non-obese Type 2 Diabetic Rats

Yonekura Y, Fujii H, Nakai K, Kono K, Goto S, ShinoharaM, Nishi S

2015 48 Orthop J Sports Med 2015 7 3 7 ###### #####Can Platelet-Rich Plasma Protect Rat Achilles Tendons Fromthe Deleterious Effects of Triamcinolone Acetonide

Muto T, Kokubu T, Mifune Y, Inui A, Sakata R, Harada Y,Takase F, Ueda Y, Kuroda R, Kurosaka M

2015 49

Proc Natl Acad Sci U S A 2015 7 112 27 8332 7Paternal allelic mutation at the Kcnq1 locus reducespancreatic β-cell mass by epigenetic modification of Cdkn1c

Asahara S, Etoh H, Inoue H, Teruyama K, Shibutani Y,Ihara Y, Kawada Y, Bartolome A, Hashimoto N, Matsuda T,Koyanagi-Kimura M, Kanno A, Hirota Y, Hosooka T,Nagashima K, Nishimura W, Inoue H, Matsumoto M, HigginsMJ, Yasuda K, Inagaki N, Seino S, Kasuga M, Kido Y

2015 50 Proc Natl Acad Sci U S A 2015 7 112 30 9406 11Glucose-dependent acetylation of Rictor promotes targetedcancer therapy resistance

Masui K, Tanaka K, Ikegami S, Villa GR, Yang H, Yong WH,Cloughesy TF, Yamagata K, Arai N, Cavenee WK, Mischel

2015 51 J Neurosci 2015 7 35 27 9879 88Neuronal Differentiation in Schwann Cell Lineage UnderliesPostnatal Neurogenesis in the Enteric Nervous System

Uesaka T, Nagashimada M, Enomoto H

2015 52 Am J Pathol 2015 7 185 7 2025 37Restoration of Functional Glycosylation of α-Dystroglycan inFKRP Mutant Mice Is Associated with Muscle Regeneration

Awano H, Blaeser A, Keramaris E, Xu L, Tucker J, Wu B,Lu P, Lu QL

2015 53 PLoS One 2015 7 10 7e0134113

e0134113

Non-Hematopoietic and Hematopoietic SIRPα SignalingDifferently Regulates Murine B Cell Maturation in Bone Marrow

Kolan SS, Lejon K, Koskinen Holm C, Sulniute R, LundbergP, Matozaki T, Oldenborg PA

2015 54 PAIN RESEARCH 2015 7 302号

70 70 痛みと情動 ストレスによる情動変化と脳内の自然免疫系 古屋敷 智之

2015 55PLoS One 2015 6 10 6

e0130032

e0130032

Downregulation of CXCR4 in Metastasized Breast Cancer Cellsand Implication in Their Dormancy

Nobutani K, Shimono Y, Mizutani K, Ueda Y, Suzuki T,Kitayama M, Minami A, Momose K, Miyawaki K, Akashi K,Azuma T, Takai Y

2015 56

PLoS One 2015 6 10 6e0130757

e0130757

Regulation of Pancreatic β Cell Mass by Cross-Interactionbetween CCAAT Enhancer Binding Protein β Induced byEndoplasmic Reticulum Stress and AMP-Activated ProteinKinase Activity

Matsuda T, Takahashi H, Mieda Y, Shimizu S, KawamotoT, Matsuura Y, Takai T, Suzuki E, Kanno A, Koyanagi-Kimura M, Asahara S, Bartolome A, Yokoi N, Inoue H,Ogawa W, Seino S, Kido Y

2015 57 Behav Pharmacol 2015 6 26 4 345 52Methylone-induced hyperthermia and lethal toxicity: role of thedopamine and serotonin transporters

Piao YS, Hall FS, Moriya Y, Ito M, Ohara A, Kikura-HanajiriR, Goda Y, Lesch KP, Murphy DL, Uhl GR, Sora I

2015 58 PLoS One 2015 6 10 6e0128805

e0128805

Dexamethasone and BCAA Failed to Modulate Muscle Massand mTOR Signaling in GH-Deficient Rats

Nishida H, Ikegami A, Kaneko C, Kakuma H, Nishi H,Tanaka N, Aoyama M, Usami M, Okimura Y

2015 59 Transl Psychiatry 2015 6 5 e577 e577Deletion of Rapgef6, a candidate schizophrenia susceptibilitygene, disrupts amygdala function in mice

Levy RJ, Kvajo M, Li Y, Tsvetkov E, Dong W, Yoshikawa Y,Kataoka T, Bolshakov VY, Karayiorgou M, Gogos JA

2015 60

Circulation 2015 6 131 24 e531 2

Response to Letter Regarding Article, "18F-Fluorodeoxyglucose Positron Emission Tomography/ComputedTomography Enables the Detection of Recurrent Same-SiteDeep Vein Thrombosis by Illuminating Recently Formed,

Tawakol A, Hara T, Truelove J, Wojtkiewicz GR, HuckerWJ, MacNabb MH, Brownell AL, Jokivarsi K, KessingerCW, Jaff MR, Henke PK, Weissleder R, Jaffer FA

2015 61 PLoS One 2015 6 10 6e0127178

e0127178

Regulation of Phagocyte Migration by Signal RegulatoryProtein-Alpha Signaling

Alvarez-Zarate J, Matlung HL, Matozaki T, Kuijpers TW,Maridonneau-Parini I, van den Berg TK

2015 62 Sci Rep 2015 6 5 10536 #####The Wnt5a-Ror2 axis promotes the signaling circuit betweeninterleukin-12 and interferon-γ in colitis

Sato A, Kayama H, Shojima K, Matsumoto S, Koyama H,Minami Y, Nojima S, Morii E, Honda H, Takeda K, Kikuchi A

2015 63 Neuromuscul Disord 2015 6 25 6 474 84Dystroglycanopathy muscles lacking functional glycosylation ofalpha-dystroglycan retain regeneration capacity

Awano H, Blaeser A, Wu B, Lu P, Keramaris-Vrantsis E,Lu Q

2015 64 Behav Pharmacol 2015 6 26 4 345 52Methylone-induced hyperthermia and lethal toxicity: role of thedopamine and serotonin transporters

Piao YS, Hall FS, Moriya Y, Ito M, Ohara A, Kikura-HanajiriR, Goda Y, Lesch KP, Murphy DL, Uhl GR, Sora I

2015 65 J Neurosci Res 2015 5 93 5 788 95Neuroprotective effects of cutamesine, a ligand of the sigma-1receptor chaperone, against noise-induced hearing loss

Yamashita D, Sun GW, Cui Y, Mita S, Otsuki N, Kanzaki S,Nibu K, Ogawa K, Matsunaga T

2015 66 Diabetes 2015 4 64 4 1262 72Role of Epac2A/Rap1 Signaling in Interplay Between Incretinand Sulfonylurea in Insulin Secretion

Takahashi H, Shibasaki T, Park JH, Hidaka S, Takahashi T,Ono A, Song DK, Seino S

2015 67 Curr Drug Targets 2015 4Identification of Lipid Species Linked to the Progression ofNon-alcoholic Fatty Liver Disease

Kawano Y, Nishiumi S, Saito M, Yano Y, Azuma T, YoshidaM

2015 68 Psychopharmacology (Berl) 2015 4 232 8 1471 82Sex differences in the effects of adolescent social deprivationon alcohol consumption in μ-opioid receptor knockout mice

Moriya Y, Kasahara Y, Hall FS, Sakakibara Y, Uhl GR,Tomita H, Sora I

2015 69Hypertension 2015 4 65 4 889 95

Foxp3 Regulatory T Cells Play a Protective Role in AngiotensinII-Induced Aortic Aneurysm Formation in Mice

Yodoi K, Yamashita T, Sasaki N, Kasahara K, Emoto T,Matsumoto T, Kita T, Sasaki Y, Mizoguchi T, SparwasserT, Hirata K

2015 70J Clin Invest 2015 4 125 4 1591 602

Compensatory glutamine metabolism promotes glioblastomaresistance to mTOR inhibitor treatment

Tanaka K, Sasayama T, Irino Y, Takata K, Nagashima H,Satoh N, Kyotani K, Mizowaki T, Imahori T, Ejima Y, MasuiK, Gini B, Yang H, Hosoda K, Sasaki R, Mischel PS,

2015 71Mol Nutr Food Res 2015 4 59 4 729 40

Trans-fatty acid promotes thrombus formation in mice byaggravating antithrombogenic endothelial functions via Toll-likereceptors

Kondo K, Ishida T, Yasuda T, Nakajima H, Mori K, TanakaN, Mori T, Monguchi T, Shinohara M, Irino Y, Toh R,Rikitake Y, Kiyomizu K, Tomiyama Y, Yamamoto J, Hirata

2015 72Genes Cells 2015 4

Regulation by gut commensal bacteria of carcinoembryonicantigen-related cell adhesion molecule expression in theintestinal epithelium

Kitamura Y, Murata Y, Park JH, Kotani T, Imada S, SaitoY, Okazawa H, Azuma T, Matozaki T

2015 73

J Clin Biochem Nutr 2015 3 56 2 155 62

Combined treatment with dipeptidyl peptidase 4 (DPP4)inhibitor sitagliptin and elemental diets reduced indomethacin-induced intestinal injury in rats via the increase of mucosalglucagon-like peptide-2 concentration

Fujiwara K, Inoue T, Yorifuji N, Iguchi M, Sakanaka T,Narabayashi K, Kakimoto K, Nouda S, Okada T, Ishida K,Abe Y, Masuda D, Takeuchi T, Fukunishi S, Umegaki E,Akiba Y, Kaunitz JD, Higuchi K

2015 74

J Gastroenterol Hepatol 2015 3 30Suppl1

60 5The effects of a TGR5 agonist and a dipeptidyl peptidase IVinhibitor on dextran sulfate sodium-induced colitis in mice

Sakanaka T, Inoue T, Yorifuji N, Iguchi M, Fujiwara K,Narabayashi K, Kakimoto K, Nouda S, Okada T, KuramotoT, Ishida K, Abe Y, Takeuchi T, Umegaki E, Akiba Y,Kaunitz JD, Higuchi K

2015 75 FEBS Lett 2015 3 589 7 849 56CHF5074 (CSP-1103) stabilizes human transthyretin in micehumanized at the transthyretin and retinol-binding protein loci

Mu Y, Jin S, Shen J, Sugano A, Takaoka Y, Qiang L,Imbimbo BP, Yamamura K, Li Z

2015 76 Jpn J Infect Dis 2015 3Immunogenicity of a candidate DNA vaccine based on theprM/E genes of a dengue type 2 virus Cosmopolitan genotype

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2015 77 Am J Transplant 2015 3A Novel Dual Ex Vivo Lung Perfusion Technique ImprovesImmediate Outcomes in an Experimental Model of Lung

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2015 78Neurobiol Aging 2015 3 36 3 1356 68

The CCAAT/enhancer-binding proteindelta/miR135a/thrombospondin 1 axis mediates PGE2-inducedangiogenesis in Alzheimer's disease

Ko CY, Chu YY, Narumiya S, Chi JY, Furuyashiki T, AokiT, Wang SM, Chang WC, Wang JM

2015 79Mucosal Immunol 2015 3 8 2 279 95

Interferon-γ-producing B cells induce the formation of gastriclymphoid follicles after Helicobacter suis infection

Yang L, Yamamoto K, Nishiumi S, Nakamura M, Matsui H,Takahashi S, Dohi T, Okada T, Kakimoto K, Hoshi N,Yoshida M, Azuma T

2015 80Biochem Biophys ResCommun

2015 3 458 3 681 6Compensatory hyperinsulinemia in high-fat diet-induced obesemice is associated with enhanced insulin translation in islets

Kanno A, Asahara S, Masuda K, Matsuda T, Kimura-Koyanagi M, Seino S, Ogawa W, Kido Y

2015 81 Mol Med Rep 2015 3 11 3 1601 8Cyclin‑dependent kinase inhibitor p21 does not impactembryonic endochondral ossification in mice

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2015 82J Orthop Res 2015 3 33 3 359 65

Oxidative stress-induced apoptosis and matrix loss ofchondrocytes is inhibited by eicosapentaenoic acid

Sakata S, Hayashi S, Fujishiro T, Kawakita K, Kanzaki N,Hashimoto S, Iwasa K, Chinzei N, Kihara S, Haneda M,Ueha T, Nishiyama T, Kuroda R, Kurosaka M

2015 83Spine J 2015 3 15 3 417 26

Functional impact of integrin α5β1 on the homeostasis ofintervertebral discs: a study of mechanotransduction pathwaysusing a novel dynamic loading organ culture system

Kurakawa T, Kakutani K, Morita Y, Kato Y, Yurube T,Hirata H, Miyazaki S, Terashima Y, Maeno K, Takada T,Doita M, Kurosaka M, Inoue N, Masuda K, Nishida K

2015 84Am J Sports Med 2015 3 43 3 700 8

Age-dependent healing potential of anterior cruciate ligamentremnant-derived cells

Nakano N, Matsumoto T, Takayama K, Matsushita T, ArakiD, Uefuji A, Nagai K, Zhang S, Inokuchi T, Nishida K,Kuroda R, Kurosaka M

2015 85 Int Orthop 2015 3 39 3 569 76Comparative analysis of rat mesenchymal stem cells derivedfrom slow and fast skeletal muscle in vitro

Okumachi E, Lee SY, Niikura T, Iwakura T, Dogaki Y, WakiT, Takahara S, Ueha T, Sakai Y, Kuroda R, Kurosaka M

2015 86 Genes Cells 2015 3Dendritic cell SIRPα regulates homeostasis of dendritic cellsin lymphoid organs

Washio K, Kotani T, Saito Y, Respatika D, Murata Y,Kaneko Y, Okazawa H, Ohnishi H, Fukunaga A, Nishigori C,

2015 87Mol Cell Biol 2015 2

Shp2 in forebrain neurons regulates synaptic plasticity,locomotion, and memory formation in mice

Kusakari S, Saitow F, Ago Y, Shibasaki K, Sato-HashimotoM, Matsuzaki Y, Kotani T, Murata Y, Hirai H, Matsuda T,Suzuki H, Matozaki T, Ohnishi H

2015 88World J Gastroenterol 2015 2 21 6 1880 6

Effects of oral tacrolimus as a rapid induction therapy inulcerative colitis

Kawakami K, Inoue T, Murano M, Narabayashi K, Nouda S,Ishida K, Abe Y, Nogami K, Hida N, Yamagami H, WatanabeK, Umegaki E, Nakamura S, Arakawa T, Higuchi K

2015 89 J Biol Chem 2015 2 290 7 3894 909Protein-tyrosine Phosphatase Shp2 Positively RegulatesMacrophage Oxidative Burst

Li XJ, Goodwin CB, Nabinger SC, Richine BM, Yang Z,Hanenberg H, Ohnishi H, Matozaki T, Feng GS, Chan RJ

2015 90 PLoS One 2015 2 10 2Carbonate ion-enriched hot spring water promotes skin woundhealing in nude rats

Liang J, Kang D, Wang Y, Yu Y, Fan J, Takashi E

2015 91 Genes Cells 2015 2Preferential gene expression and epigenetic memory ofinduced pluripotent stem cells derived from mouse pancreas

Nukaya D, Minami K, Hoshikawa R, Yokoi N, Seino S

2015 92Biol Psychiatry 2015 2 77 4 335 44

Neonatal maternal separation alters the capacity of adultneural precursor cells to differentiate into neurons viamethylation of retinoic Acid receptor gene promoter

Boku S, Toda H, Nakagawa S, Kato A, Inoue T, Koyama T,Hiroi N, Kusumi I

2015 93 FASEB J 2015 2Actin polymerization-enhancing drugs promote ovarian folliclegrowth mediated by the Hippo signaling effector YAP

Cheng Y, Feng Y, Jansson L, Sato Y, Deguchi M,Kawamura K, Hsueh AJ

2015 94 Hippocampus 2015 2Turning off of GluN2B subunits and on of CICR in hippocampalLTD induction after developmental GluN2 subunit switch

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2015 95Microcirculation 2015 2 22 2 122 32

The short-term effects of C-peptide on the early diabetes-related ultrastructural changes to the podocyte slit diaphragmof glomeruli in rats

Nakamoto H, Nakayama K, Emoto N, Kajiya F

2015 96 J Virol 2015 2Maturation of human herpesvirus-6A glycoprotein O requirescoexpression of gH and gL

Tang H, Mahmoud NF, Mori Y

2015 97 Sci Rep 2015 2 5 8316 8316Fukutin is prerequisite to ameliorate muscular dystrophicphenotype by myofiber-selective LARGE expression

Ohtsuka Y, Kanagawa M, Yu CC, Ito C, Chiyo T, KobayashiK, Okada T, Takeda S, Toda T

2015 98 Andrologie 2015 2Clusterin produced by Sertoli cells inhibits heat stress-inducedapoptosis in the rat testis

Matsushita K, Miyake H, Chiba K, Fujisawa M

2015 99 Cancer Discov 2015 2 5 2 198 211Promotion of Colorectal Cancer Invasion and Metastasisthrough Activation of NOTCH-DAB1-ABL-RHOGEF Protein

Sonoshita M, Itatani Y, Kakizaki F, Sakimura K, TerashimaT, Katsuyama Y, Sakai Y, Taketo MM

2015 100J Bone Miner Res 2015 1 30 1 95 105

SDF-1/CXCR4 axis in Tie2-lineage cells including endothelialprogenitor cells contributes to bone fracture healing

Kawakami Y, Ii M, Matsumoto T, Kuroda R, Kuroda T,Kwon SM, Kawamoto A, Akimaru H, Mifune Y, Shoji T,Fukui T, Kurosaka M, Asahara T

2015 101 J Appl Toxicol 2015 1 9Bisphenol A exposure induces metabolic disorders andenhances atherosclerosis in hyperlipidemic rabbits

Fang C, Ning B, Waqar AB, Niimi M, Li S, Satoh K, ShiomiM, Ye T, Dong S, Fan J

2015 102 Bone 2015 1 74C 153 15922-Oxacalcitriol attenuates bone loss in nonobese type 2diabetes

Goto S, Fujii H, Kono K, Nakai K, Awata R, Yonekura Y,Hirata M, Shinohara M, Nishi S, Fukagawa M

2015 103 Ann Rheum Dis 2015 1MicroRNA-124 inhibits the progression of adjuvant-inducedarthritis in rats

Nakamachi Y, Ohnuma K, Uto K, Noguchi Y, Saegusa J,Kawano S

2015 104 PLoS One 2015 1 10 1e0117547

e0117547

A High-Fat Diet Delays Age-Related Hearing Loss Progressionin C57BL/6J Mice

Fujita T, Yamashita D, Uehara N, Inokuchi G, Hasegawa S,Otsuki N, Nibu K

2015 105 Kobe J Med Sci 2015 0 61 4 E115 E123Expression of Beta Subunit 2 of Ca2+/Calmodulin-DependentProtein Kinase I in the Developing Rat Retina

Jusuf AA, Sakagami H, Kikkawa S, Terashima T

2015 106 Circ J 2015 0 79 9 1882 90Intestinal Immunity and Gut Microbiota as Therapeutic Targetsfor Preventing Atherosclerotic Cardiovascular Diseases

Yamashita T, Kasahara K, Emoto T, Matsumoto T,Mizoguchi T, Kitano N, Sasaki N, Hirata K

2015 107 Kobe J Med Sci 2015 0 61 3 E71 E81Postnatal Development of the Corticospinal Tract in theReeler Mouse

Namikawa T, Kikkawa S, Inokuchi G, Terashima T

2015 108Biomed Res Int 2015 0 2015 ###### #####

Candesartan Mediated Amelioration of Cisplatin-InducedTesticular Damage Is Associated with Alterations in ExpressionPatterns of Nephrin and Podocin

Enatsu N, Miyake H, Chiba K, Fujisawa M

2015 109Int J Food Sci Nutr 2015 0

Catechins in tea suppress the activity of cytochrome P4501A1 through the aryl hydrocarbon receptor activation pathwayin rat livers

Fukuda I, Nishiumi S, Mukai R, Yoshida KI, Ashida H

2015 110Curr Mol Med 2015 0 15 3 245 52

Improvement of learning and increase in dopamine level in thefrontal cortex by methylphenidate in mice lacking dopaminetransporter

Takamatsu Y, Hagino Y, Sato A, Takahashi T, NagasawaSY, Kubo Y, Mizuguchi M, Uhl GR, Sora I, Ikeda K

2015 111 Curr Mol Med 2015 0 15 3 237 44Region-specific dendritic spine loss of pyramidal neurons indopamine transporter knockout mice

Kasahara Y, Arime Y, Hall FS, Uhl GR, Sora I

2015 112

Curr Mol Med 2015 0 15 3 265 74

The Piccolo Intronic Single Nucleotide Polymorphismrs13438494 Regulates Dopamine and Serotonin Uptake andShows Associations with Dependence-Like Behavior inGenomic Association Study

Uno K, Nishizawa D, Seo S, Takayama K, Matsumura S,Sakai N, Ohi K, Nabeshima T, Hashimoto R, Ozaki N,Hasegawa J, Sato N, Tanioka F, Sugimura H, Fukuda KI,Higuchi S, Ujike H, Inada T, Iwata N, Sora I, Iyo M, KondoN, Won MJ, Naruse N, Uehara-Aoyama K, Itokawa M,

2015 113 Biosci Biotechnol Biochem 2015 0 79 11 1867 75Chicken heat shock protein HSPB1 increases and interactswith αB-crystallin in aged skeletal muscle

Ueda S, Kokaji Y, Simizu S, Honda K, Yoshino K,Kamisoyama H, Shirai Y, Yamanoue M

2015 114 Metabolomics 2015 0 11 5 1277 1286Identification of putative biomarkers for prediabetes bymetabolome analysis of rat models of type 2 diabetes

Yokoi N, Beppu M, Yoshida E, Hoshikawa R, Hidaka S,Matsubara T, Shinohara M, Irino Y, Hatano N, Seino S

2015 115Evid Based ComplementAlternat Med

2015 0 2015 ###### #####Rikkunshito Ameliorates Cancer Cachexia Partly throughElevation of Glucarate in Plasma

Ohbuchi K, Nishiumi S, Fujitsuka N, Hattori T, YamamotoM, Inui A, Azuma T, Yoshida M

2015 116 J DIABETES RES 2015 0 2015 ###### #####Characterization of the Prediabetic State in a Novel Rat Modelof Type 2 Diabetes, the ZFDM Rat

Gheni G, Yokoi N, Beppu M, Yamaguchi T, Hidaka S,Kawabata A, Hoshino Y, Hoshino M, Seino S

2015 117 J OPHTHALMOL 2015 0 2015 ###### #####Proteomic study of retinal proteins associated withtranscorneal electric stimulation in rats

Kanamoto T, Souchelnytskyi N, Kurimoto T, Ikeda Y,Sakaue H, Munemasa Y, Kiuchi Y

2015 118Oxid Med Cell Longev 2015 0 2015 ###### #####

Dietary Tocotrienol/γ-Cyclodextrin Complex IncreasesMitochondrial Membrane Potential and ATP Concentrations inthe Brains of Aged Mice

Schloesser A, Esatbeyoglu T, Piegholdt S, Dose J, IkutaN, Okamoto H, Ishida Y, Terao K, Matsugo S, Rimbach G

2015 119Int J Food Sci Nutr 2015

Catechins in tea suppress the activity of cytochrome P4501A1 through the aryl hydrocarbon receptor activation pathwayin rat livers

Fukuda I, Nishiumi S, Mukai R, Yoshida KI, Ashida H

2015 120Curr Mol Med 2015 15 3 245 52

Improvement of learning and increase in dopamine level in thefrontal cortex by methylphenidate in mice lacking dopaminetransporter

Takamatsu Y, Hagino Y, Sato A, Takahashi T, NagasawaSY, Kubo Y, Mizuguchi M, Uhl GR, Sora I, Ikeda K

2015 121 Curr Mol Med 2015 15 3 237 44Region-specific dendritic spine loss of pyramidal neurons indopamine transporter knockout mice

Kasahara Y, Arime Y, Hall FS, Uhl GR, Sora I

2015 122

Curr Mol Med 2015 15 3 265 74

The Piccolo Intronic Single Nucleotide Polymorphismrs13438494 Regulates Dopamine and Serotonin Uptake andShows Associations with Dependence-Like Behavior inGenomic Association Study

Uno K, Nishizawa D, Seo S, Takayama K, Matsumura S,Sakai N, Ohi K, Nabeshima T, Hashimoto R, Ozaki N,Hasegawa J, Sato N, Tanioka F, Sugimura H, Fukuda KI,Higuchi S, Ujike H, Inada T, Iwata N, Sora I, Iyo M, KondoN, Won MJ, Naruse N, Uehara-Aoyama K, Itokawa M,

2015 123 癌と化学療法 2015 10 4210号

1252 1255NK細胞浸潤がヒト乳がん異種移植マウスの腫瘍増殖に与える影響

向山 順子, 下野 洋平, 船越 洋平, 河野 誠之, 山下 公大,向原 徹, 高尾 信太郎, 南 博信, 掛地 吉弘

2015 124 臨床化学 2015 10 44 4 282 289 腸内細菌と循環器疾患 江本 拓央, 山下 智也, 平田 健一

2015 125薬理と治療 2015 10 43 10 1409 1416

ンジオテンシンII誘発性大動脈瘤形成に対するn-3系多価不飽和脂肪酸EPAとDHAの差異の検討

淀井 景子, 山下 智也, 河野 浩之, 佐々木 直人, 北 智之,笠原 和之, 佐々木 義浩, 松本 卓也, 江本 拓央, 溝口 泰司, 林 友鴻, 平田 健一

2015 126 日本整形外科学会雑誌 2015 9 898号

S1674 S1674 骨肉腫細胞に対するSmac模倣薬と抗癌剤の併用効果の検討蒲田 悦子, 河本 旭哉, 上羽 岳志, 原 仁美, 大西 康央, 簑田 正也, 森下 雅之, 黒坂 昌弘, 秋末 敏宏

2015 127 医学のあゆみ 2015 9 25412号

1115 1120【プロスタグランジンと炎症】 ストレスによる情動制御におけるPGE2-EP1系の役割

古屋敷 智之

2015 128 日本整形外科学会雑誌 2015 9 898号

S1802 S1802 AICARの骨肉腫細胞に対するアポトーシス誘導効果森下 雅之, 河本 旭哉, 大西 康央, 蓑田 正也, 蒲田 悦子,原 仁美, 上羽 岳志, 黒坂 昌弘, 秋末 敏宏

2015 129日本整形外科学会雑誌 2015 9 89

9号

579 584椎間板変性と臨床　未来への展望 椎間板変性の発生機序と臨床との関連について

西田 康太郎, 角谷 賢一朗, 前野 耕一郎, 高田 徹, 由留部崇, 山本 潤哉, 平田 裕亮, 蔵川 拓外, 酒井 大輔, 持田 讓治, 舛田 浩一, 森田 有亮, 黒坂 昌弘

2015 130

実験医学 2015 9 3315号

2468 2473

【脂質疾患学　なぜあぶらの異常が病気を引き起こすのか?その質的量的変化と肥満、がん、不妊症、免疫・皮膚・神経疾患】(第2章)多彩な疾患における脂質の量的・質的変化　神経疾患ドパミン依存的な情動行動におけるPGE2-EP1経路の役割と精

北岡 志保, 古屋敷 智之

2015 131 日本整形外科学会雑誌 2015 6 896号

S1227 S1227骨肉腫細胞に対するSmac模倣薬とアドリアマイシンの併用効果

蒲田 悦子, 河本 旭哉, 原 仁美, 大西 康央, 簑田 正也, 森下 雅之, 上羽 岳志, 黒坂 昌弘, 秋末 敏宏

2015 132 神経眼科 2015 6 322号

142 147 【NMO 前線】 モデル動物による視神経脊髄炎の研究 金森 章泰

2015 133 細胞 2015 6 476号

270 273【プロスタグランジンによる病態制御の 前線】 ストレス関連行動におけるCOX-1-PGE2-EP1系の役割

古屋敷 智之

2015 134 Bio Clinica 2015 6 4 2 50 55 慢性炎症制御による動脈硬化予防 山下 智也, 佐々木 直人, 平田 健一

2015 135 日本整形外科学会雑誌 2015 6 896号

S1241 S1241 AICARの骨肉腫細胞に対するアポトーシス誘導効果森下 雅之, 河本 旭哉, 蓑田 正也, 大西 康央, 原 仁美, 上羽 岳志, 蒲田 悦子, 黒坂 昌弘, 秋末 敏宏

2015 136 日本整形外科学会雑誌 2015 6 896号

S1238 S1238Survivin抑制薬"YM155"は骨肉腫細胞において腫瘍増殖を抑制する

蓑田 正也, 河本 旭哉, 上羽 岳志, 原 仁美, 大西 康央, 森下 雅之, 蒲田 悦子, 黒坂 昌弘, 秋末 敏宏

2015 137 脊椎脊髄ジャーナル 2015 1 281号

25 31 【椎間板と痛み】 椎間板変性の疼痛発生機序について西田 康太郎, 高田 徹, 前野 耕一郎, 角谷 賢一朗, 由留部崇, 黒坂 昌弘

2015 138 実験医学 2015 1 331号

124 126糖尿病成因解明の 前線 インスリン分泌を増強するシグナルのインタープレイとその臨床的示唆

高橋 晴美, グプルジャン・ゲニ , 清野 進

2015 139 日本整形外科学会雑誌 2015 1 891号

26 32骨関節の再生医療の現状と展望 自家末梢血CD34陽性細胞を用いた骨・血管再生療法に関する第I・II相臨床試験

松本 知之, 新倉 隆宏, 川上 洋平, 福井 友章, 美舩 泰, 李相亮, 川本 篤彦, 黒坂 昌弘, 浅原 孝之, 黒田 良祐

2014 1 Int J Radiat Oncol Biol Phys 2014 12 90 5 1177 85Preclinical evaluation of bioabsorbable polyglycolic acid spacerfor particle therapy

Akasaka H, Sasaki R, Miyawaki D, Mukumoto N, SulaimanNS, Nagata M, Yamada S, Murakami M, Demizu Y,

2014 2

Nat Med 2014 12 20 12 1372 5IL-18 is not therapeutic for neovascular age-related maculardegeneration

Hirano Y, Yasuma T, Mizutani T, Fowler BJ, Tarallo V,Yasuma R, Kim Y, Bastos-Carvalho A, Kerur N, GelfandBD, Bogdanovich S, He S, Zhang X, Nozaki M, Ijima R,Kaneko H, Ogura Y, Terasaki H, Nagai H, Haro I, Núñez G,Ambati BK, Hinton DR

2014 3

Oncotarget 2014 12

Haploinsufficiency of the c-myc transcriptional repressor FIR,as a dominant negative-alternative splicing model, promotedp53-dependent T-cell acute lymphoblastic leukemiaprogression by activating Notch1

Matsushita K, Kitamura K, Rahmutulla B, Tanaka N, IshigeT, Satoh M, Hoshino T, Miyagi S, Mori T, Itoga S, ShimadaH, Tomonaga T, Kito M, Nakajima-Takagi Y, Kubo S,Nakaseko C, Hatano M, Miki T, Matsuo M, Fukuyo M,Kaneda A, Iwama A, Nomura F

2014 4 J Gen Virol 2014 12 95Pt12

2769 77Human herpesvirus 6 gM/gN complex interacts with v-SNAREin infected cells

Kawabata A, Serada S, Naka T, Mori Y

2014 5Biomaterials 2014 12 35 37 9904 11

Intra-articular administration of gelatin hydrogels incorporatingrapamycin-micelles reduces the development of experimentalosteoarthritis in a murine model

Matsuzaki T, Matsushita T, Tabata Y, Saito T, MatsumotoT, Nagai K, Kuroda R, Kurosaka M

2014 6 Exp Eye Res 2014 12 129 38 47The expression of syntaphilin is down-regulated in the opticnerve after axonal injury

Miki A, Kanamori A, Nakamura M, Matsumoto Y, MizokamiJ, Negi A

2014 7 J Bone Joint Surg Am 2014 12 96 24 2077 84Topical cutaneous CO2 application by means of a novelhydrogel accelerates fracture repair in rats

Koga T, Niikura T, Lee SY, Okumachi E, Ueha T, IwakuraT, Sakai Y, Miwa M, Kuroda R, Kurosaka M

2014 8 Bone Joint Res 2014 12 3 12 328 34Dose- and time-dependent effects of triamcinolone acetonideon human rotator cuff-derived cells

Harada Y, Kokubu T, Mifune Y, Inui A, Sakata R, Muto T,Takase F, Kurosaka M

2014 9 Arthritis Rheumatol 2014 12Tofacitinib facilitates the expansion of myeloid-derivedsuppressor cells and ameliorates arthritis in SKG mice

Nishimura K, Saegusa J, Matsuki F, Akashi K, KageyamaG, Morinobu A

2014 10Life Sci 2014 11 118 2 313 28

Inhibition of vascular endothelial growth factor receptor underhypoxia causes severe, human-like pulmonary arterialhypertension in mice: potential roles of interleukin-6 and

Van Hung T, Emoto N, Vignon-Zellweger N, Nakayama K,Yagi K, Suzuki Y, Hirata K

2014 11Mol Ther 2014 11 22 11 1890 9

Muscle and heart function restoration in a limb girdle musculardystrophy 2I (LGMD2I) mouse model by systemic FKRP genedelivery

Qiao C, Wang CH, Zhao C, Lu P, Awano H, Xiao B, Li J,Yuan Z, Dai Y, Martin CB, Li J, Lu Q, Xiao X

2014 12

ELIFE 2014 11 3.doi

10 10miR-142 regulates the tumorigenicity of human breast cancerstem cells through the canonical WNT signaling pathway

Isobe T, Hisamori S, Hogan DJ, Zabala M, HendricksonDG, Dalerba P, Cai S, Scheeren F, Kuo AH, Sikandar SS,Lam JS, Qian D, Dirbas FM, Somlo G, Lao K, Brown PO,Clarke MF, Shimono Y

2014 13Cell Signal 2014 11 26 11 2460 9

Role of the guanine nucleotide exchange factor in Akt2-mediated plasma membrane translocation of GLUT4 in insulin-stimulated skeletal muscle

Takenaka N, Yasuda N, Nihata Y, Hosooka T, Noguchi T,Aiba A, Satoh T

2014 14 Int Orthop 2014 11 38 11 2413 20A new bioabsorbable cotton-textured synthetic polymerscaffold for osteochondral repair

Sakata R, Kokubu T, Mifune Y, Inui A, Nishimoto H, FujiokaH, Kuroda R, Kurosaka M

2014 15 Int J Artif Organs 2014 11 371-11

854 60Development of a novel method for decellularizing a nervegraft using a hypertonic sodium chloride solution

Ishida Y, Sakakibara S, Terashi H, Hashikawa K, YamaokaT

2014 16 Int J Pharm 2014 10 4731-2

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Sawaengsak C, Mori Y, Yamanishi K, Srimanote P,Chaicumpa W, Mitrevej A, Sinchaipanid N

2014 17 PLoS One 2014 10 9 10e110549

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Genetic ablation of afadin causes mislocalization anddeformation of Paneth cells in the mouse small intestinal

Tanaka-Okamoto M, Itoh Y, Miyoshi J, Mizoguchi A,Mizutani K, Takai Y, Inoue M

2014 18EuroIntervention 2014 10 10 6 717 23

Comparison of vascular response between durable andbiodegradable polymer-based drug-eluting stents in a porcinecoronary artery model

Nakazawa G, Shinke T, Ijichi T, Matsumoto D, Otake H,Torii S, Hiranuma N, Ohsue T, Otsuka F, Shite J, Hirata K,Ikari Y

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Nat Commun 2014 10 5 5214 5214miR-24 limits aortic vascular inflammation and murineabdominal aneurysm development

Maegdefessel L, Spin JM, Raaz U, Eken SM, Toh R,Azuma J, Adam M, Nagakami F, Heymann HM,Chernugobova E, Jin H, Roy J, Hultgren R, Caidahl K,Schrepfer S, Hamsten A, Eriksson P, McConnell MV,

2014 20 PLoS One 2014 10 9 10e110977

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Bisphenol A exposure enhances atherosclerosis in WHHLrabbits

Fang C, Ning B, Waqar AB, Niimi M, Li S, Satoh K, ShiomiM, Ye T, Dong S, Fan J

2014 21Nat New Biol 2014 10 514 ## 98 101

The neurotrophic factor receptor RET drives haematopoieticstem cell survival and function

Fonseca-Pereira D, Arroz-Madeira S, Rodrigues-CamposM, Barbosa IA, Domingues RG, Bento T, Almeida AR,Ribeiro H, Potocnik AJ, Enomoto H, Veiga-Fernandes H

2014 22 J Clin Invest 2014 10 124 10 4517 28Platelet secretion and hemostasis require syntaxin-bindingprotein STXBP5

Ye S, Huang Y, Joshi S, Zhang J, Yang F, Zhang G, SmythSS, Li Z, Takai Y, Whiteheart SW

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CELL REP 2014 10 9 2 661 73Glutamate acts as a key signal linking glucose metabolism toincretin/cAMP action to amplify insulin secretion

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2014 40 Ann Rheum Dis 2014 7 73 7 1397 404Disruption of Sirt1 in chondrocytes causes acceleratedprogression of osteoarthritis under mechanical stress and

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2014 53 Trop Med Health 2014 3 42 1 35 42Dynamics of Centrocestus armatus transmission in an endemicriver in Hyogo Prefecture, Japan

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2014 54Rheumatology (Oxford) 2014 3

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2014 57 J Vasc Interv Radiol 2014 3 25 3 469 76Inhibition of Growth in a Rabbit VX2 Thigh Tumor Model withIntraarterial Infusion of Carbon Dioxide-Saturated Solution

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2014 59 Virology 2014 2 450-451 98 105 Characterization of the human herpesvirus 6A U23 geneHayashi M, Yoshida K, Tang H, Sadaoka T, Kawabata A,Jasirwan C, Mori Y

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2014 64 PLoS One 2014 2 9 2 e89763 e89763Afadin regulates puncta adherentia junction formation andpresynaptic differentiation in hippocampal neurons

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2014 66 Cancer Lett 2014 2 343 1 74 9Synergistic effects of pemetrexed and amrubicin in non-smallcell lung cancer cell lines: Potential for combination therapy

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2014 67 J Immunol 2014 2 192 4 1512 24Posttranscriptional Modulation of Cytokine Production in TCells for the Regulation of Excessive Inflammation by TFL

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2014 68 Exp Eye Res 2014 2 119 61 9Sera from patients with seropositive neuromyelitis opticaspectral disorders caused the degeneration of rodent optic

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2014 70 Methods 2014 1 65 2 254 9Autoimmune animal models in the analysis of the CD47-SIRPα signaling pathway

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2014 71Cancer Cell 2014 1 25 1 102 17

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2014 73 Development 2014 1 141 2 399 409Aberrant cochlear hair cell attachments caused by Nectin-3deficiency result in hair bundle abnormalities

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2014 74 J Invest Dermatol 2014 1Intratumoral CD4+ T Lymphodepletion Sensitizes PoorlyImmunogenic Melanomas to Immunotherapy with an OX40

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2014 78 Intern Med 2014 53 15 1699 703Liver abscess caused by CTX-M-55-type extended-spectrumβ-lactamase (ESBL)-producing Salmonella enteritidis

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2014 79 Mediators Inflamm 2014 2014 979132 1E+06Effects of antisense oligonucleotides against C-reactiveprotein on the development of atherosclerosis in WHHL rabbits

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2014 80 Biosci Biotechnol Biochem 2014 78 1221 1230Protective effects of oral administration of yeast thioredoxinagainst gastric mucosal injury

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2014 81 J Atheroscler Thromb 2014 21 7 648 58Probucol suppresses macrophage infiltration and MMPexpression in atherosclerotic plaques of WHHL rabbits

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2014 83Digestion 2014 90 1 10 7

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2014 84 Adv Neurobiol 2014 8 91 116Roles of nectins and nectin-like molecules in the nervoussystem

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2014 85 日本内科学会雑誌 2014 11 10311号

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2014 87 IVR: Interventional Radiology 2014 8 293号

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2014 89 日本放射光学会誌　放射光 2014 27 1 3 9rasがん遺伝子産物の新規立体構造情報を利用した分子標的がん治療薬の開発

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2013 1Neurosci Res 2013 12 77 4 222 7

Association analysis of the DISC1 gene with schizophrenia inthe Japanese population and DISC1 immunoreactivity in thepostmortem brain

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2013 2 Clin Transl Oncol 2013 12Characterization of mechanism involved in acquired resistanceto sorafenib in a mouse renal cell cancer RenCa model

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2013 4 AAPS PharmSciTech 2013 12Chitosan Nanoparticle Encapsulated Hemagglutinin-SplitInfluenza Virus Mucosal Vaccine

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2013 5 Parasitol Res 2013 12 112 12 4009 13Development of free-living stages of Strongyloides ratti underdifferent temperature conditions

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2013 6 PLoS One 2013 11 8 11 e80356 e80356Genetic deletion of afadin causes hydrocephalus bydestruction of adherens junctions in radial glial and ependymal

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2013 7JAMA Dermatol 2013 11 149 11 1308 13

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2013 11 33 11 2518 23Vasospasm of atherosclerotic coronary arteries precipitatesacute ischemic myocardial damage in myocardial infarction-prone strain of the Watanabe heritable hyperlipidemic rabbits

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2013 9Atherosclerosis 2013 11 231 1 39 47

Contribution of the WHHL rabbit, an animal model of familialhypercholesterolemia, to elucidation of the anti-atheroscleroticeffects of statins

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2013 10 Cell Metab 2013 11 18 5 749 58Osteocytes regulate primary lymphoid organs and fatmetabolism

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2013 11 Kobe J Med Sci 2013 11 59 4 E122 31Localization and Characterization of a Novel Secreted Protein,SCUBE2, in the Development and Progression of

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2013 13 Surg Endosc 2013 11 27 11 4241 9Endoscopic submucosal dissection using a carbon dioxide laserwith submucosally injected laser absorber solution (porcine

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2013 14 Sci Rep 2013 11 3 3288 3288AGO61-dependent GlcNAc modification primes the formationof functional glycans on α-dystroglycan

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2013 15 PLoS One 2013 10 8 10 e76201 e76201Regulation of dendritic filopodial interactions by ZO-1 andimplications for dendrite morphogenesis

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2013 16Biochem Biophys ResCommun

2013 10 440 1 184 9Mediator subunit MED1 is a T3-dependent and T3-independent coactivator on the thyrotropin β gene promoter

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2013 10 440 1 125 31FGF7 supports hematopoietic stem and progenitor cells andniche-dependent myeloblastoma cells via autocrine action onbone marrow stromal cells in vitro

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2013 10 440 1 25 30Mutant γPKC that causes spinocerebellar ataxia type 14upregulates Hsp70, which protects cells from the mutant'scytotoxicity

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2013 10 440 1 88 93GTDC2 modifies O-mannosylated α-dystroglycan in theendoplasmic reticulum to generate N-acetyl glucosamineepitopes reactive with CTD110.6 antibody

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2013 20J Spinal Disord Tech 2013 10 26 7 E281 5

Efficacy of hemostasis for epidural venous plexus and safetyfor neural structure using soft coagulation system in spinalsurgery: a laboratory investigation using a porcine model

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2013 21 J Neurosci 2013 10 33 41 16372 82GDNF signaling levels control migration and neuronaldifferentiation of enteric ganglion precursors

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IL-27 enhances the expression of TRAIL and TLR3 in humanmelanomas and inhibits their tumor growth in cooperation witha TLR3 agonist poly(I:C) partly in a TRAIL-dependent manner

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2013 23Proc Natl Acad Sci U S A 2013 10 110 43 17474 9

Hippo signaling disruption and Akt stimulation of ovarianfollicles for infertility treatment

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2013 24 Microbiol Immunol 2013 10 57 10 704 14Novel polyvalent live vaccine against varicella-zoster andmumps virus infections

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Clin Cancer Res 2013 10 19 20 5722 32The mTOR kinase inhibitors, CC214-1 and CC214-2,preferentially block the growth of EGFRvIII-activatedglioblastomas

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2013 26J Biol Chem 2013 10 288 41 29333 44

Lack of CD47 impairs bone cell differentiation and results in anosteopenic phenotype in vivo due to impaired signal regulatoryprotein α (SIRPα) signaling

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2013 27 Cell Metab 2013 10 18 4 491 504Semaphorin3E-induced inflammation contributes to insulinresistance in dietary obesity

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2013 43 Biomaterials 2013 7 34 22 5476 87Tendon graft revitalization using adult anterior cruciateligament (ACL)-derived CD34 cell sheets for ACL

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2013 44 Neurotherapeutics 2013 7 10 3 440 6Inhibition of protein misfolding/aggregation using polyglutaminebinding peptide QBP1 as a therapy for the polyglutamine

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2013 48 Mol Immunol 2013 6 54 2 199 207Podoplanin is an inflammatory protein upregulated in Th17 cellsin SKG arthritic joints

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2013 51 PLoS One 2013 6 8 6 e68134 e68134An Adaptor Molecule Afadin Regulates Lymphangiogenesis byModulating RhoA Activity in the Developing Mouse Embryo

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2013 52 FASEB J 2013 6 27 6 2175 84Oocyte-derived R-spondin2 promotes ovarian follicledevelopment

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2013 53 J Virol 2013 6 87 12 7054 63Identification of the human herpesvirus 6A gQ1 domainessential for its functional conformation

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2013 54 Cell Stem Cell 2013 6 12 6 737 47Matrix-embedded osteocytes regulate mobilization ofhematopoietic stem/progenitor cells

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2013 3 33 6 1206Nectin-Like Molecule-5 Regulates Intimal Thickening AfterCarotid Artery Ligation in Mice

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2013 59 Genes Cells 2013 3 18 3 195 202miR-214 and hypoxia down-regulate Necl-2/CADM1 andenhance ErbB2/ErbB3 signaling

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Boron neutron capture therapy (BNCT) selectively destroyshuman clear cell sarcoma in mouse model

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2013 62Blood 2013 2 121 8 1316 25

Polymorphic Sirpa is the genetic determinant for NOD-basedmouse lines to achieve efficient human cell engraftment

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Therapeutic advantage in selective ligament augmentation forpartial tears of the anterior cruciate ligament: results in ananimal model

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Linoleoyl ethanolamide reduces lipopolysaccharide-inducedinflammation in macrophages and ameliorates 2,4-dinitrofluorobenzene-induced contact dermatitis in mice

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2013 65 PLoS One 2013 1 8 1 e53490 e53490Kif14 mutation causes severe brain malformation andhypomyelination

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2013 66 Dig Dis Sci 2013 1Claudin-2 Regulates Colorectal Inflammation via Myosin LightChain Kinase-Dependent Signaling

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2013 67 Photochem Photobiol 2013 1 89 649 654 Hydrochlorothiazide Enhances UVA-Induced DNA DamageKunisada M, Masaki T, Ono R, Morinaga H, Nakano E,Yogianti F, Okunishi K, Sugiyama H, Nishigori C

2013 68 Osteoarthritis Cartilage 2013 1 21 1 175 85The effect of platelet-rich plasma on the regenerative therapyof muscle derived stem cells for articular cartilage repair

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2013 69Biochem Biophys ResCommun

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2013 70Hepatology 2013 1 57 1 362 72

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2013 71 Nucl Med Biol 2013 1 40 1 97 103Radioiodinated peptide probe for selective detection ofoxidized low density lipoprotein in atherosclerotic plaques

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2013 72 J Diabetes Res 2013 0 2013 103731 9 pages 9 pagesA Novel Rat Model of Type 2 Diabetes: The Zucker FattyDiabetes Mellitus ZFDM Rat

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2013 73 SPring-8 Research Frontiers 2013 0Structure-based drug design of small-molecule Ras inhibitorshaving anti-tumor activity

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2013 74Cell Transplant 2013 0 22 7 1201 11

Therapeutic Superiority for Cartilage Repair by CD271 PositiveMarrow Stromal Cell Transplantation

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2013 75 Nat Med 2013 0 20 1 123 126GLP-1 receptor activation and Epac2 link atrial natriureticpeptide secretion to control of blood pressure

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2013 76 J Biochem Pharmacol Res 2013 0 1 4 212 218Safety evaluation of R(+)-alpha lipoic acid-gamma cyclodextrincomplex

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2013 79 Sci Rep 2013 0 3 2190 2190Collagen morphology and texture analysis: from statistics toclassification

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2013 82 J Pain Res 2013 0 6 87 94Spinal nerve injury causes upregulation of ErbB2 and ErbB3receptors in rat dorsal root ganglia

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2013 83 Nat Commun 2013 0 4 2436 2436Inflammation-induced proteolytic processing of the SIRPαcytoplasmic ITIM in neutrophils propagates a proinflammatory

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2013 84Biomed Res Int 2013 0 2013 109580 109580

A comparative histopathology, serology and molecular study,on experimental ocular toxocariasis by Toxocara cati inMongolian gerbils and Wistar rats

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2013 85 Tohoku J Exp Med 2013 0 229 3 195 201D-ribose ameliorates cisplatin-induced nephrotoxicity byinhibiting renal inflammation in mice

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2013 86 Am J Nephrol 2013 0 37 2 167 74Anti-oxidative effect of vitamin d analog on incipient vascularlesion in non-obese type 2 diabetic rats

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2013 87 Kobe J Med Sci 2013 0 59 1 in press in pressTyrosine phosphorylation of Carcinoembryonic Antigen-relatedCell Adhesion Molecule 20 and its functional roles

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2013 88 Nat Med 2013 0 20 1 123 126GLP-1 receptor activation and Epac2 link atrial natriureticpeptide secretion to control of blood pressure

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2013 89 医学のあゆみ 2013 9 24610号

893 901【制御性T細胞-その基礎と臨床展開】 動脈硬化症における制御性T細胞の役割

佐々木 直人, 平田 健一

2013 90循環器専門医 2013 9 21

2号

291 296心臓と他臓器のコミュニケーションを探る　臓器関連から考える新しい循環器病治療戦略　腸管は心血管病予防の新たな治療ターゲットになる

山下 智也, 佐々木 直人, 平田 健一

2013 91 日本臨床内科医会会誌 2013 9 283号

353 353先端医療はどこまで進んだか 先端医療はどこまで進んだか?運動器の損傷を再生医療で治す

黒田 良祐

2013 92 日本整形外科学会雑誌 2013 8 878号

S1321 S1321ヒト軟骨細胞においてPTENは酸化ストレス下に基質の産生を調整する

岩佐 賢二郎, 林 申也, 藤代 高明, 神崎 至幸, 橋本 慎吾,坂田 周平, 鎮西 伸顕, 黒田 良祐, 黒坂 昌弘

2013 93 アンチ・エイジング医学 2013 8 94号

541 547【サルコペニアとアンチエイジング】 筋肉研究の 前線　筋ジストロフィー

戸田 達史

2013 94 日本整形外科学会雑誌 2013 8 878号

S1322 S1322エイコサペンタエン酸は酸化ストレス依存性の軟骨細胞の変性、アポトーシスを抑制する

坂田 周平, 藤代 高明, 林 申也, 神崎 至幸, 橋本 慎吾, 岩佐 賢二郎, 鎮西 伸顕, 黒田 良祐, 黒坂 昌弘

2013 95 日本整形外科学会雑誌 2013 8 878号

S1520 S1520軟骨変性の病態 長寿因子SIRT1による軟骨変性と変形性関節症における役割

松下 雄彦, 黒田 良祐, 松崎 時夫, 高山 孝治, 石田 一成,佐々木 宏, 松本 知之, 藤田 周史, 長井 寛斗, 黒坂 昌弘

2013 96 日本整形外科学会雑誌 2013 8 878号

S1605 S1605マウス変形性関節症モデルにおける徐放化rapamycin投与の関節症進行抑制効果

松崎 時夫, 松下 雄彦, 高山 孝治, 松本 知之, 岡 真也, 長井 寛斗, 上藤 淳郎, 齊藤 高志, 田畑 泰彦, 黒田 良祐, 黒

2013 97 日本整形外科学会雑誌 2013 8 878号

S1508 S1508膝前十字靱帯由来細胞の細胞特性における年齢による差異の検討

上藤 淳郎, 松本 知之, 松下 雄彦, 川上 洋平, 岡 真也, 西澤 勇一郎, 松崎 時夫, 長井 寛斗, 黒田 良祐, 黒坂 昌弘

2013 98 日本整形外科学会雑誌 2013 8 878号

S1359 S1359 ヒト軟骨細胞における長寿遺伝子SIRT6による役割の検討長井 寛斗, 松下 雄彦, 松崎 時夫, 松本 知之, 張 樹蓉, 高山 孝治, 岡 真也, 西澤 勇一郎, 上藤 淳郎, 黒田 良祐, 黒

2012 1 Invest Ophthalmol Vis Sci 2012 12 53 13 8029 35Forskolin modifies retinal vascular development in Mrp4-knockout mice

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2012 2 Biotechnol Lett 2012 12 34 12 2175 82T-5224, a selective inhibitor of c-Fos/activator protein-1,attenuates lipopolysaccharide-induced liver injury in mice

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2012 3 Vasc Med 2012 12 17 6 379 85Inhibition of Rho-kinase attenuates endothelial-leukocyteinteraction during ischemia-reperfusion injury

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2012 4J Cell Sci 2012 12

Analysis of the angulin family consisting of LSR, ILDR1 andILDR2: tricellulin recruitment, epithelial barrier function andimplication in deafness pathogenesis

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2012 5 Med Sci Sports Exerc 2012 12The Use of Blood Vessel-Derived Stem Cells for MeniscalRegeneration and Repair

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2012 6 Diabetes 2012 11 61 11 2980 6Increased inner ear susceptibility to noise injury in mice withstreptozotocin-induced diabetes

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2012 7 Kobe J Med Sci 2012 11 58 3 E86 95Subcortically and callosally projecting neurons are distinctneuronal pools in the motor cortex of the reeler mouse

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2012 8 Int Orthop 2012 11 36 11 2379 86Ligament regeneration using an absorbable stent-shaped poly-L-lactic acid scaffold in a rabbit model

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2012 9 BMC Nephrol 2012 11 13 153 159The effects of a selective inhibitor of c-Fos/activator protein-1 on endotoxin-induced acute kidney injury in mice

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2012 10Mutagenesis 2012 11 27 6 637 43

Skin tumours induced by narrowband UVB have higherfrequency of p53 mutations than tumours induced bybroadband UVB independent of Ogg1 genotype

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2012 11 428 4 475 81Hypothermia-dependent and -independent effects of forcedswim on the phosphorylation states of signaling molecules inmouse hippocampus

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2012 12 J Cell Sci 2012 11 125 Pt 22 5535 45Macrophages require Skap2 and Sirpα for integrin-stimulatedcytoskeletal rearrangement

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2012 13Urology 2012 10 80 4 951 951

Potential establishment of lung metastatic xenograft model ofandrogen receptor-positive and androgen-independentprostate cancer (C4-2B)

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2012 14 J Dermatol 2012 10 39 10 843 51Suppressive effect of recombinant human thioredoxin onultraviolet light-induced inflammation and apoptosis in murine

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2012 15Comp Med 2012 10 62 5 409 18

Electrocardiograms corresponding to the development ofmyocardial infarction in anesthetized WHHLMI rabbits(Oryctolagus cuniculus), an animal model for familial

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2012 16 J Biochem 2012 10 152 4 347 53PKL01, an Ndr kinase homologue in plant, shows tyrosinekinase activity

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2012 17 J Cell Sci 2012 10 125 Pt 20 4923 33A novel protein complex, Mesh-Ssk, is required for septatejunction formation in the Drosophila midgut

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2012 18Cell Transplant 2012 10

Therapeutic Superiority for Cartilage Repair by CD271 PositiveMarrow Stromal Cell Transplantation

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2012 19Nutrition 2012 10 28 1-10 967 72

Plasma ghrelin isoforms and gastric ghrelin O-acyltransferaseexpression are influenced by Helicobacter pylori status

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2012 20 J Dermatol 2012 9 39 9 792 4Successful treatment with adapalene of cetuximab-inducedacneiform eruptions

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Regulation of insulin signaling by the phosphatidylinositol 3,4,5-triphosphate phosphatase SKIP through the scaffoldingfunction of Pak1

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2012 24 J Agric Food Chem 2012 9 60 36 9315 20Suppression of lipopolysaccharide and galactosamine-inducedhepatic inflammation by red grape pomace

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DPP4 inhibitor vildagliptin preserves β-cell mass throughamelioration of endoplasmic reticulum stress in C/EBPBtransgenic mice

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Development of oxidized phosphatidylcholine isomer profilingmethod using supercritical fluid chromatography/tandem massspectrometry

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2012 28 J Neurochem 2012 8 122 4 834 43SHPS-1 deficiency induces robust neuroprotection againstexperimental stroke by attenuating oxidative stress

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2012 29 Exp Dermatol 2012 7 21 Suppl 1 31 5Effect of chemical peeling on the skin in relation to UVirradiation

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2012 30 Int J Oncol 2012 7 41 1 201 10Biological significance of tumor budding at the invasive front ofhuman colorectal carcinoma cells

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2012 31 Exp Dermatol 2012 7 21 7 557 9Claudin-5 haploinsufficiency exacerbates UVB-inducedoedema formation by inducing lymphatic vessel leakage

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Nitric oxide prevents phosphorylation of neuronal nitric oxidesynthase at serine1412 by inhibiting the Akt/PKB and CaM-KII signaling pathways

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2012 34 Am J Pathol 2012 7 181 1 62 73Retrograde and Wallerian axonal degeneration occursynchronously after retinal ganglion cell axotomy

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Eleven novel mutations of the ADAR1 gene in dyschromatosissymmetrica hereditaria

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A novel feedback mechanism by Ephrin-B1/B2 in T-cellactivation involves a concentration-dependent switch fromcostimulation to inhibition

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Highly sensitive and rapid profiling method for carotenoids andtheir epoxidized products using supercritical fluidchromatography coupled with electrospray ionization-triplequadrupole mass spectrometry

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Platelet activation receptor CLEC-2 regulates blood/lymphaticvessel separation by inhibiting proliferation, migration, and tubeformation of lymphatic endothelial cells

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Hypothermia-induced tyrosine phosphorylation of SIRPα inthe brain

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Integrated clinical, pathologic, virologic, and transcriptomicanalysis of H5N1 influenza virus-induced viral pneumonia in therhesus macaque

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2012 49Eur J Radiol 2012 6 81 6 1330 4

Reduced-dose chest CT with 3D automatic exposure controlvs. standard chest CT: Quantitative assessment ofemphysematous changes in smokers' lung parenchyma

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Transcutaneous application of carbon dioxide (CO2) inducesmitochondrial apoptosis in human malignant fibroushistiocytoma in vivo

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2012 52 J Atheroscler Thromb 2012 0 19 12 1110 27Expression of endothelial lipase correlates with the size ofneointima in a murine model of vascular remodeling

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Myocardial infarction-prone Watanabe heritable hyperlipidemicrabbits with mesenteric fat accumulation are a novel animalmodel for metabolic syndrome

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2012 55 Cell Transplant 2012 0 21 8 1651 65Therapeutic potential of anterior cruciate ligament-derivedstem cells for anterior cruciate ligament reconstruction

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Arhgef15 promotes retinal angiogenesis by mediating VEGF-induced Cdc42 activation and potentiating RhoJ inactivation inendothelial cells

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The hedgehog signal induced modulation of bonemorphogenetic protein signaling: an essential signaling relay forurinary tract morphogenesis

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2012 58 NAT COMMUN 2012 0 3 1120 1120MyD88 signalling in colonic mononuclear phagocytes drivescolitis in IL-10-deficient mice

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Evaluation of atherosclerotic lesions using dextran- andmannan–dextran-coated USPIO: MRI analysis and pathologicalfindings

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2012 60J Atheroscler Thromb 2012 0 19 3 213 26

Endothelial lipase mediates HDL levels in normal andhyperlipidemic rabbits

Zhang J, Yu Y, Nakamura K, Koike T, Waqar AB, Zhang X,Liu E, Nishijima K, Kitajima S, Shiomi M, Qi Z, Yu J,Graham MJ, Crooke RM, Ishida T, Hirata K, Hurt-Camejo

2012 61Cell Transplant 2012 0 21 4 707 21

Local transplantation of granulocyte colony-stimulating factor-mobilized human peripheral blood mononuclear cells forunhealing bone fractures

Fukui T, Matsumoto T, Mifune Y, Shoji T, Kuroda T,Kawakami Y, Kawamoto A, Ii M, Kawamata S, Kurosaka M,Asahara T, Kuroda R

2012 62 Tohoku J Exp Med 2012 0 228 3 215 21 D-allose ameliorates cisplatin-induced nephrotoxicity in miceMiyawaki Y, Ueki M, Ueno M, Asaga T, Tokuda M,Shirakami G

2012 63Appl Phys A Mater SciProcess

2012 0Photomechanical ablation of biological tissue induced byfocused femtosecond laser and its application for acupuncture

Yoichiroh Hosokawa, Mika Ohta, Akihiko Ito, YutakaTakaoka

2012 64Cell Transplant 2012 0 21 12 2689 709

Local transplantation of ex vivo expanded bone marrow-derived CD34-positive cells accelerates fracture healing

Kawakami Y, Ii M, Alev C, Kawamoto A, Matsumoto T,Kuroda R, Shoji T, Fukui T, Masuda H, Akimaru H, MifuneY, Kuroda T, Horii M, Yokoyama A, Kurosaka M, Asahara T

2012 65 PLoS One 2012 0 7 9 e45218 e45218The absence of CD47 promotes nerve fiber growth fromcultured ventral mesencephalic dopamine neurons

Marschinke F, Hashemian S, Matozaki T, Oldenborg PA,Strömberg I

2012 66上原記念生命科学財団研究報告集

2012 12 26 1 5 細胞極性制御の破綻と疾患の関連解析 南 康博

2012 67 移植 2012 12 476

号497 498 自家末梢血CD34陽性細胞による難治性骨折の治療

黒田 良祐, 新倉 隆宏, 松本 知之, 李 相亮, 美舩 泰, 古賀敬章, 川上 洋平, 堂垣 佳宏, 奥町 悦子, 黒坂 昌弘

2012 68 整形・災害外科 2012 10 5511号

1286 1287分子レベルからみた整形外科疾患(シリーズIX)　MFH細胞株に対する血管新生阻害剤bevacizumabの効果

原 仁美, 秋末 敏宏, 岡田 欣之, 河本 旭哉, 黒坂 昌弘

2012 69 炎症と免疫 2012 10 206

号596 600 粘膜免疫におけるFc受容体の役割 増田 充弘, Yahaya Bensuleiman, 西海 信, 東 健, 吉田 優

2012 70 日本レーザー医学会誌 2012 10 333

号278 278

消化器科におけるレーザーの現状と新展開 CO2レーザーによる新しい消化器内視鏡治療技術の開発

森田 圭紀, 小畑 大輔, 東 健, 岡上 吉秀, 石井 克典, 間久直, 粟津 邦男

2012 71 整形・災害外科 2012 10 5511号

1341 1346【骨・関節のバイオメカニクス- 近の進歩】 脊椎椎間板の力学的特性　動的負荷培養装置を用いた機械受容体の検討

蔵川 拓外, 角谷 賢一朗, 森田 有亮, 前野 耕一郎, 黒坂昌弘, 西田 康太郎

2012 72 肩関節 2012 9 363

号913 916

ポリ乳酸・グリコール酸(PLG)スカフォールドを使用した家兎肩腱板再生の試み

乾 淳幸, 国分 毅, 坂田 亮介, 美舩 泰, 無藤 智之, 藤岡宏幸

2012 73 整形外科 2012 9 6310号

1060 1060 末梢血細胞を用いた骨・血管再生療法による偽関節治療 松本 知之, 黒田 良祐

2012 74 日本整形外科学会雑誌 2012 8 868

号S1332 S1332

ヒト軟骨細胞においてPTENはtype II collagenの発現を制御する

岩佐 賢二郎, 西山 隆之, 林 申也, 藤代 高明, 川北 晃平,神崎 至幸, 橋本 慎吾, 坂田 周平, 黒田 良祐, 黒坂 昌弘

2012 75 日本整形外科学会雑誌 2012 8 868

号S1232 S1232 炭酸ガス経皮吸収はラットの骨折治癒を促進する

古賀 敬章, 新倉 隆宏, 李 相亮, 堂垣 佳宏, 奥町 悦子, 上羽 岳志, 酒井 良忠, 大江 啓介, 黒田 良祐, 三輪 雅彦, 黒

2012 76 日本整形外科学会雑誌 2012 8 868

号S1190 S1190

低出力超音波パルスはBMP-7によるヒト偽関節組織由来細胞の骨分化を促進する

古賀 敬章, 李 相亮, 新倉 隆宏, 堂垣 佳宏, 奥町 悦子, 黒田 良祐, 黒坂 昌弘

2012 77 日本整形外科学会雑誌 2012 8 868

号S1225 S1225 筋損傷を科学する 炭酸ガス経皮吸収の筋肉への効果

酒井 良忠, 大江 啓介, 三輪 雅彦, 上羽 岳志, 新倉 隆宏,李 相亮, 黒田 良祐, 黒坂 昌弘

2012 78 日本整形外科学会雑誌 2012 8 868

号S1268 S1268

炭酸ガス経皮吸収が運動後のラットの筋肉に及ぼす影響について

大江 啓介, 酒井 良忠, 新倉 隆宏, 李 相亮, 古賀 敬章, 堂垣 佳宏, 上羽 岳志, 田中 雅也, 三輪 雅彦, 黒田 良祐, 黒

2012 79 日本整形外科学会雑誌 2012 8 868

号S1191 S1191 Rasファミリーの偽関節部における発現と局在の検討

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2012 80整形・災害外科 2012 8 55

9号

1056 1057分子レベルからみた整形外科疾患(シリーズIX)　骨折治癒遅延モデルに対する胎生期分化誘導シグナル(Sonic hedgehog)再構築の治療効果

庄司 太郎, 伊井 正明, 松本 知之, 黒田 良祐, 黒坂 昌弘,浅原 孝之

2012 81 関節外科 2012 7 317

号742 748

【肩の腱板-基礎から学ぶ臨床-】 人工吸収性材料による肩腱板の再生　家兎棘下筋腱による検討

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2012 82 生体の科学 2012 6 633

号224 228

【細胞極性の制御】 非古典的Wntシグナルによる極性と幹細胞性維持の制御

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2012 83 あたらしい眼科 2012 6 296

号736 742

【神経眼科- 新の話題】 視神経炎に抗AQP4抗体を検査すべきか?治療法は変わるか?

中村 誠

2012 84 分子消化器病 2012 0 9 2 22 27ガスクロマトグラフ質量分析計を用いたメタボローム解析による消化管疾患診断に向けて

吉田優、寺島禎彦、西海信、和泉自泰、東健

2011 1 Am J Pathol 201112 179 6 3056 65

Increased expression of versican in the inflammatory response toUVB- and reactive oxygen species-induced skin tumorigenesis.

Kunisada M, Yogianti F, Sakumi K, Ono R, Nakabeppu Y, NishigoriC.

2011 2Appl Radiat Isot 2011

12 69 12 1721 4

Boron neutron capture therapy for clear cell sarcoma (CCS):biodistribution study of p-borono-L-phenylalanine in CCS-bearinganimal models.

Andoh T, Fujimoto T, Sudo T, Fujita I, Imabori M, Moritake H,Sugimoto T, Sakuma Y, Takeuchi T, Kawabata S, Kirihata M,Akisue T, Yayama K, Kurosaka M, Miyatake S, Fukumori Y,

2011 3Appl Radiat Isot 2011

12 69 12 1713 6

Evaluation of BPA uptake in clear cell sarcoma (CCS) in vitro anddevelopment of an in vivo model of CCS for BNCT studies.

Fujimoto T, Andoh T, Sudo T, Fujita I, Imabori M, Moritake H,Sugimoto T, Sakuma Y, Takeuchi T, Sonobe H, Epstein AL,Akisue T, Kirihata M, Kurosaka M, Fukumori Y, Ichikawa H.

2011 4Int J Mol Med

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28 6 937 45

Inhibitory effects of vitamin K₃ derivatives on DNA polymerase andinflammatory activity.

Aoganghua A, Nishiumi S, Kobayashi K, Nishida M, Kuramochi K,Tsubaki K, Hirai M, Tanaka S, Azuma T, Yoshida H, Mizushina Y,Yoshida M.

2011 5J Orthop Res 2011

12 29 12 1820 6

Differential gene expression and immunolocalization of insulin-likegrowth factors and insulin-like growth factor binding proteins betweenexperimental nonunions and standard healing fractures.

Koh A, Niikura T, Lee SY, Oe K, Koga T, Dogaki Y, Kurosaka M.

2011 6 Paediatr Anaesth 201112 21 12 1209 13

Erythropoietin attenuates isoflurane-induced neurodegeneration andlearning deficits in the developing mouse brain.

Tsuchimoto T, Ueki M, Miki T, Morishita J, Maekawa N.

2011 7Sports Med Arthrosc RehabilTher Technol

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Application of layered poly (L-lactic acid) cell free scaffold in a rabbitrotator cuff defect model.

Inui A, Kokubu T, Fujioka H, Nagura I, Sakata R, Nishimoto H,Kotera M, Nishino T, Kurosaka M.

2011 8 Neurosci Res 2011 1171 3 200 9

RA-GEF-1 (Rapgef2) is essential for proper development of themidline commissures.

Bilasy SE, Satoh T, Terashima T, Kataoka T.

2011 9FEMS Immunol Med Microbiol 2011

10 63 1 25 34

IFN-γ plays an essential role in the pathogenesis of gastric lymphoidfollicles formation caused by Helicobacter suis infection.

Mimura T, Yoshida M, Nishiumi S, Tanaka H, Nobutani K,Takenaka M, Suleiman YB, Yamamoto K, Ota H, Takahashi S,Matsui H, Nakamura M, Miki I, Azuma T.

2011 10 Dig Dis Sci 20119 56 9 2532 44

A role of the aryl hydrocarbon receptor in attenuation of colitis.Furumatsu K, Nishiumi S, Kawano Y, Ooi M, Yoshie T, Shiomi Y,Kutsumi H, Ashida H, Fujii-Kuriyama Y, Azuma T, Yoshida M.

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Evid Based Complement AlternatMed

2011 09 2011 . pii 532180 532180Oral Treatment with Extract of Agaricus blazei Murill Enhanced Th1Response through Intestinal Epithelial Cells and Suppressed OVA-Sensitized Allergy in Mice

Bouike G, Nishitani Y, Shiomi H, Yoshida M, Azuma T, HashimotoT, Kanazawa K, Mizuno M

2011 12J immunol 2011

9 187 5 2268 77SIRPα/CD172a regulates eosinophil homeostasis.

Verjan Garcia N, Umemoto E, Saito Y, Yamasaki M, Hata E,Matozaki T, Murakami M, Jung YJ, Woo SY, Seoh JY, Jang MH,Aozasa K, Miyasaka M.

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Cholecystokinin facilitates neuronal excitability in the entorhinalcortex via activation of TRPC-like channels.

Wang S, Zhang AP, Kurada L, Matsui T, Lei S.

2011 14 Biochem Biophys Res Commun2011

8 412 2 197 202Role of S6K1 in regulation of SREBP1c expression in the liver.

Li S, Ogawa W, Emi A, Hayashi K, Senga Y, Nomura K, Hara K,Yu D, Kasuga M.

2011 15 Hum Mol Genet 20118 20 15 2975 83

Endoplasmic reticulum stress response in P104L mutant caveolin-3transgenic mice.

Kuga A, Ohsawa Y, Okada T, Kanda F, Kanagawa M, Toda T,Sunada Y.

2011 16J Clin Invest 2011

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Rac1 GTPase in rodent kidneys is essential for salt-sensitivehypertension via a mineralocorticoid receptor-dependent pathway.

Shibata S, Mu S, Kawarazaki H, Muraoka K, Ishizawa K, YoshidaS, Kawarazaki W, Takeuchi M, Ayuzawa N, Miyoshi J, Takai Y,Ishikawa A, Shimosawa T, Ando K, Nagase M, Fujita T.

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Modified house-keeping gene expression in a rat tail compressionloading-induced disc degeneration model.

Yurube T, Takada T, Hirata H, Kakutani K, Maeno K, Zhang Z,Yamamoto J, Doita M, Kurosaka M, Nishida K.

2011 18 Pancreas 20118 40 6 846 54

Mesenchymal stem cells facilitate mixed hematopoietic chimerisminduction and prevent onset of diabetes in nonobese diabetic mice.

Asari S, Itakura S, Rawson J, Ito T, Todorov I, Nair I, Shintaku J,Liu CP, Kandeel F, Mullen YS.

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CD47-signal regulatory protein-α (SIRPα) interactions form abarrier for antibody-mediated tumor cell destruction.

Zhao XW, van Beek EM, Schornagel K, Van der Maaden H, VanHoudt M, Otten MA, Finetti P, Van Egmond M, Matozaki T, KraalG, Birnbaum D, van Elsas A, Kuijpers TW, Bertucci F, van den

2011 20 Science 20118 233 6046 1144 7

Nectins establish a checkerboard-like cellular pattern in the auditoryepithelium.

Togashi H, Kominami K, Waseda M, Komura H, Miyoshi J,Takeichi M, Takai Y.

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In vitro and in vivo inhibitory effect of three Cox-2 inhibitors andepithelial-to-mesenchymal transition in human bladder cancer cell

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2011 22J immunol 2011

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Signal regulatory protein α regulates the homeostasis of Tlymphocytes in the spleen.

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2011 23 J Synchrotron Radiat 20117 18 Pt4 671 80

A narrow microbeam is more effective for tumor growth suppressionthan a wide microbeam: an in vivo study using implanted human glioma

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2011 24 Hepatology 20116 53 6 2016 26

Carbon monoxide enhances early liver regeneration in mice afterhepatectomy.

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2011 25J Gene Med 2011

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Intravenous injection of irradiated tumor cell vaccine carryingoncolytic adenovirus suppressed the growth of multiple lung tumors ina mouse squamous cell carcinoma model.

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2011 26 J Virol 20115 85 10 4673 8

Systemic dissemination of H5N1 influenza A viruses in ferrets andhamsters after direct intragastric inoculation.

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2011 27 Lab Invest 20115 91 5 711 8

Phospholipase Cɛ has a crucial role in ultraviolet B-inducedneutrophil-associated skin inflammation by regulating the expression

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2011 28 Biochem Biophys Res Commun 2011 04 407 1 148 52The effect of transcutaneous application of carbon dioxide (CO(2)) onskeletal muscle

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2011 29 Biomed Res 2011 0432 2 167 74

Pancreatic β-cells are generated by neogenesis from non-β-cellsafter birth.

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2011 30Cancer Sci 2011 04 102 4 769 75

Inhibition of tumor growth and sensitization to chemotherapy by RNAinterference targeting interleukin-6 in the androgen-independenthuman prostate cancer PC3 model

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2011 31 J Invest Dermatol 2011 04131 4 932 43

CD44 regulates tight-junction assembly and barrier function.Kirschner N, Haftek M, Niessen CM, Behne MJ, Furuse M, Moll I,Brandner JM.

2011 32 J Invest Dermatol 20114 131 4 956 61

Topical cholecystokinin depresses itch-associated scratchingbehavior in mice.

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2011 33 Respir Res 20114 12

Antigen-Specific IgG ameliorates allergic airway inflammation via Fcγreceptor IIB on dendritic cells.

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2011 34 Biochem Biophys Res Commun 2011 03 406 1 36 41Correlation of C4ST-1 and ChGn-2 expression with chondroitinsulfate chain elongation in atherosclerosis

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2011 35 Dig Dis Sci 2011 03 A Role of the Aryl Hydrocarbon Receptor in Attenuation of ColitisFurumatsu K, Nishiumi S, Kawano Y, Ooi M, Yoshie T, Shiomi Y,Kutsumi H, Ashida H, Fujii-Kuriyama Y, Azuma T, Yoshida M

2011 36 Exp Eye Res 2011 03 92 3 195 201Diabetes induces expression of aquaporin-0 in the retinal nerve fibersof spontaneously diabetic Torii rats

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2011 38 Proc Natl Acad Sci USA 2011 03108 10 4075 80

Claudin-4 induction by E-protein activity in later stages of CD4/8double-positive thymocytes to increase positive selection efficiency.

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2011 39 Arch Biochem Biophys 2011 02 506 2 223 35Autophagy in the intestinal epithelium reduces endotoxin-inducedinflammatory responses by inhibiting NF-κB activation

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2011 40 Inflamm Bowel Dis 2011 02 Non Non Non NonGCMS-based metabolomic study in mice with colitis induced bydextran sulfate sodium

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2011 41INT J MOL SCI 2011 02 12 2 1115 32

Effects of Intermediates between Vitamins K(2) and K(3) onMammalian DNA Polymerase Inhibition and Anti-Inflammatory Activity

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2011 42 J Cell Sci 2011 02 124 Pt 4 548 55LSR defines cell corners for tricellular tight junction formation inepithelial cells

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2011 43 Br J Surg 2011 01Risk factors for survival and local recurrence after particleradiotherapy for single small hepatocellular carcinoma

Komatsu S, Murakami M, Fukumoto T, Hori Y, Hishikawa Y, Ku Y

2011 44Eur J Immunol 2011 01 41 1 202 13

Overexpression of phospholipase Cε in keratinocytes upregulatescytokine expression and causes dermatitis with acanthosis and T-cellinfiltration

Takenaka N, Edamatsu H, Suzuki N, Saito H, Inoue Y, Oka M, HuL, Kataoka T

2011 45 J Lipid Res 2011 01 52 1 57 67Targeted deletion of endothelial lipase increases HDL particles withanti-inflammatory properties both in vitro and in vivo

Hara T, Ishida T, Kojima Y, Tanaka H, Yasuda T, Shinohara M,Toh R, Hirata K

2011 46 Med Chem 2011 01 7 1 37 44Effects of quinone derivatives, such as 1,4-naphthoquinone, on DNApolymerase inhibition and anti-inflammatory action

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2011 47 Mol Endocrinol 20111 25 1 92 103

HER2/ErbB2 receptor signaling in rat and human prolactinoma cells:strategy for targeted prolactinoma therapy.

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2011 48 Nat Neurosci 20111 14 1 31 6

An evolving NGF-Hoxd1 signaling pathway mediates development ofdivergent neural circuits in vertebrates.

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2011 49 Pancreas 2011 01 40 1 84 94Vitamin K3 attenuates cerulein-induced acute pancreatitis throughinhibition of the autophagic pathway

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2011 50 Pediatr Surg Int 2011 01 27 1 73 80Development of a model of benign esophageal stricture in rats: theoptimal concentration of sodium hydroxide for stricture formation

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2011 51 Am J Pathol 2011180 3 1273 82

Promotion of lymphatic integrity by angiopoietin-1/Tie2 signalingduring inflammation.

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2011 52Arteroscler Thromb Vasc Biol 2011

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Orally administered eicosapentaenoic acid induces rapid regression ofatherosclerosis via modulating the phenotype of dendritic cells in LDLreceptor-deficient mice.

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2011 53 Arthritis Res Ther 201113 R77

Histone deacetylase inhibition alters denfritic cells to assume atolerogenic phenotype and ameliorates arthritis in SKG mice.

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2011 54 Biochem Biophys Res Commun 2011413 224 9

A coronary artery disease-associated gene product, JCAD/KIAA1462,is a novel component of endothelial cell-cell junctions.

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2011 55 Biochem Biophys Res Commun2011

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2011 56 Biol Pharm Bull 201134 1448 54

Protective effects of soy isoflavone genistein on ischemia-reperfusionin the rat small intesitine.

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2011 57 Biopharm Drug Dispos2011 32 151 8

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2011 58 Food Chem 2011127 893 898

Protective effect of lutein after ischemia-reperfusion in the smallintestine.

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2011 59 Food Sci Technol Res 201117 353 9

Concentration of catechins and caffeine in black tea affectssuppression of fat accumulation and hyperglycemia in high-fat diet-

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2011 60 J Cell Sci 2011124 2231 40

Involvement of afadin in barrier function and homeostasis of mouseintestinal epithelia.

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2011 61 J Clin Invest 2011121 1974 85

Sema3E-PlexinD1 signaling selectively suppresses disoreintedangiogenesis in ischemic retinopathy in mice

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2011 62 J Clin Invest 2011121 4712 21

EGFR as a therapeutic target for human, canine, and mouse ACTH-secreting pituitary adenomas.

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Isolation and function of mouse tissue resident vascular precursorsmarked by myelin protein sero.

Kubota Y, Takubo K, Hirashima M, Nagoshi N, Kishi K, Okuno Y,Nakamura-Ishizu A, Sano K, Murakami M, Ema M, Omatsu Y,Takahashi S, Nagasawa T, Shibuya M, Okano H, Suda T

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Ablation of TSC2 enhances insulin secretion by increasing the numberof mitochondria through activation of mTORC1.

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PDK1-Foxo1 in agouti-related peptide neurons regulates energyhomeostasis by modulating food intake and energy expenditure.

Cao Y, Nakata M, Okamoto S, Takano E, Yada T, Minokoshi Y,Hirata Y, Nakajima K, Iskandar K, Hayashi Y, Ogawa W, Barsh GS,Hosoda H, Kangawa K, Itoh H, Noda T, Kasuga M, Nakae J.

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PlGF repairs myocardial ischemia through mechanisms ofangiogenesis, cardioprotection and recruitment of myo-angiogeniccompetent marrow progenitors.

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2010 1 Endocrine 2010 12 38 3 369 76The effects of the receptor for advanced glycation end products(RAGE) on bone metabolism under physiological and diabetic

Hamada Y, Kitazawa S, Kitazawa R, Kono K, Goto S, Komaba H,Fujii H, Yamamoto Y, Yamamoto H, Usami M, Fukagawa M

2010 2Arterioscler Thromb Vasc Biol 2010 12 30 12 2495 503

Oral administration of an active form of vitamin D3 (calcitriol)decreases atherosclerosis in mice by inducing regulatory T cells andimmature dendritic cells with tolerogenic functions

Takeda M, Yamashita T, Sasaki N, Nakajima K, Kita T, ShinoharaM, Ishida T, Hirata K

2010 3 Blood 2010 12 116 25 5528 35Role for vitamin D receptor in the neuronal control of thehematopoietic stem cell niche

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2010 4J Agric Food Chem 2010 12 58 24 12916 23

Green and black tea suppress hyperglycemia and insulin resistance byretaining the expression of glucose transporter 4 in muscle of high-fatdiet-fed C57BL/6J mice

Nishiumi S, Bessyo H, Kubo M, Aoki Y, Tanaka A, Yoshida K,Ashida H

2010 5FEMS Immunol Med Microbiol 2010 11 60 2 156 64

Helicobacter heilmannii can induce gastric lymphoid follicles in micevia a Peyer's patch-independent pathway

Nobutani K, Yoshida M, Nishiumi S, Nishitani Y, Takagawa T,Tanaka H, Yamamoto K, Mimura T, Bensuleiman Y, Ota H,Takahashi S, Matsui H, Nakamura M, Azuma T

2010 6 Int J Mol Med 2010 11 26 5 751 8Inhibitory effects of sulfobacin B on DNA polymerase andinflammation

Maeda J, Nishida M, Takikawa H, Yoshida H, Azuma T, YoshidaM, Mizushina Y

2010 7Oncol Rep 2010 11 24 5 1395 9

The antiandrogen bicalutamide activates the androgen receptor (AR)with a mutation in codon 741 through the mitogen activated proteinkinase (MARK) pathway in human prostate cancer PC3 cells

Terakawa T, Miyake H, Kumano M, Sakai I, Fujisawa M

2010 8 J Biol Chem 2010 10 285 41 31208 16Post-translational maturation of dystroglycan is necessary forpikachurin binding and ribbon synaptic localization

Kanagawa M, Omori Y, Sato S, Kobayashi K, Miyagoe-Suzuki Y,Takeda S, Endo T, Furukawa T, Toda T

2010 9 J Dermatol 2010 10 37 10 864 72 Effect of chemical peeling on photocarcinogenesisAbdel-Daim M, Funasaka Y, Kamo T, Ooe M, Matsunaka H,Yanagita E, Itoh T, Nishigori C

2010 10 Tissue Eng Part A 2010 10 16 10 3271 84Bone regeneration properties of granulocyte colony-stimulating factorvia neovascularization and osteogenesis

Ishida K, Matsumoto T, Sasaki K, Mifune Y, Tei K, Kubo S,Matsushita T, Takayama K, Akisue T, Tabata Y, Kurosaka M,

2010 11Clin Vaccine Immunol 2010 10 17 10 1560 6

Evaluation of extracellular subviral particles of dengue virus type 2and Japanese encephalitis virus produced by Spodoptera frugiperdacells for use as vaccine and diagnostic antigens

Kuwahara M, Konishi E

2010 12 J Vasc Surg 2010 10 52 4 967 74Activation of transglutaminase type 2 for aortic wall protection in arat abdominal aortic aneurysm formation

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2010 13Mol Cell Biol 2010 10 30 20 4818 27

The transcriptional mediator subunit MED1/TRAP220 in stromal cellsis involved in hematopoietic stem/progenitor cell support throughosteopontin expression

Sumitomo A, Ishino R, Urahama N, Inoue K, Yonezawa K,Hasegawa N, Horie O, Matsuoka H, Kondo T, Roeder RG, Ito M

2010 14 Carcinogenesis 2010 10 31 10 1897 902Enhancement of ultraviolet B-induced skin tumor development inphospholipase Cε-knockout mice is associated with decreased cell

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2010 15 J Dermatol Sci 2010 10 60 1 21 8Preventive effect of chemical peeling on ultraviolet induced skintumor formation

Abdel-Daim M, Funasaka Y, Kamo T, Ooe M, Matsunaka H,Yanagita E, Itoh T, Nishigori C

2010 16 Kobe J Med Sci 2010 09 56 2 E50 59Cortical layer V neurons in the auditory and visual cortices of normal,reeler, and yotari mice

Yoshihara Y, Setsu T, Katsuyama Y, Kikkawa S, Terashima T,Maeda K

2010 17 Microvasc Res 2010 09 80 2 179 87Endothelial cell-selective adhesion molecule modulatesatherosclerosis through plaque angiogenesis and monocyte-

Inoue M, Ishida T, Yasuda T, Toh R, Hara T, Cangara HM,Rikitake Y, Taira K, Sun L, Kundu RK, Quertermous T, Hirata K

2010 18 Invest Ophthalmol Vis Sci 2010 09 51 9 4618 26Reduced expression of aquaporin-9 in rat optic nerve head and retinafollowing elevated intraocular pressure

Naka M, Kanamori A, Negi A, Nakamura M

2010 19 Anticancer Res 2010 09 30 9 3391 5The effect of bevacizumab on tumour growth of malignant fibroushistiocytoma in an animal model

Okada Y, Akisue T, Hara H, Kishimoto K, Kawamoto T, ImaboriM, Kishimoto S, Fukase N, Onishi Y, Kurosaka M

2010 20 Immunotherapy 2010 09 2 5 697 709Antimelanoma immunotherapy: clinical and preclinical applications ofIL-12 family members

Nagai H, Oniki S, Fujiwara S, Yoshimoto T, Nishigori C

2010 21 J Thorac Cardiovasc Surg 2010 08 140 2 400 7Excessively high systemic blood pressure in the early phase ofreperfusion exacerbates early-onset paraplegia in rabbit aortic

Pokhrel B, Hasegawa T, Izumi S, Ohmura A, Munakata H, OkitaY, Okada K

2010 22 J Thorac Cardiovasc Surg 2010 08 140 2 408 416Pioglitazone preserves vein graft integrity in a rat aortic interpositionmodel

Chen Z, Hasegawa T, Tanaka A, Okita Y, Okada K

2010 23 J Dent Res 2010 08 89 8 854 9 Efficient cell-seeding into scaffolds improves bone formationHasegawa T, Miwa M, Sakai Y, Niikura T, Lee SY, Oe K, IwakuraT, Kurosaka M, Komori T

2010 24 J Surg Res 2010 08 162 2 284 9Effect of Oxygenated Perfluorocarbon on Isolated Islets DuringTransportation

Terai S, Tsujimura T, Li S, Hori Y, Toyama H, Shinzeki M,Matsumoto I, Kuroda Y, Ku Y

2010 25 Kobe J Med Sci 2010 08 56 1 E1 11The novel VEGF receptor antagonist, VGA1155, reduces edema,decreases infarct and improves neurological function after stroke in

Koyama J, Miyake S, Sasayama T, Chiba Y, Kondoh T, KohmuraE

2010 26 Cell Metab 2010 08 12 2 117 29Rim2alpha determines docking and priming states in insulin granuleexocytosis

Yasuda T, Shibasaki T, Minami K, Takahashi H, Mizoguchi A, UriuY, Numata T, Mori Y, Miyazaki J, Miki T, Seino S

2010 27 Ann Otol Rhinol Laryngol 2010 08 119 8 535 40 Bone marrow stem cell transplantation to olfactory epithelium Ochi N, Doi K, Uranagase M, Nishikawa T, Katsunuma S, Nibu K

2010 28FASEB J 2010 07 24 7 2254 61

Crucial role of the small GTPase Rac1 in insulin-stimulatedtranslocation of glucose transporter 4 to the mouse skeletal musclesarcolemma

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2010 29Diabetes 2010 07 59 7 1608 15

Role of KLF15 in regulation of hepatic gluconeogenesis and metforminaction

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2010 30 BJU Int 2010 07 106 1 121 7Suppressed tumour growth and enhanced chemosensitivity by RNAinterference targeting Aurora-A in the PC3 human prostate cancer

Kumano M, Miyake H, Terakawa T, Furukawa J, Fujisawa M

2010 31 J Dermatol 2010 07 37 7 635 46Pharmacogenomics of metabotropic glutamate receptor subtype 1 andin vivo malignant melanoma formation

Abdel-Daim M, Funasaka Y, Komoto M, Nakagawa Y, Yanagita E,Nishigori C

2010 32 Clin Immunol 2010 07 136 1 74 82Administration of a determinant of preproinsulin can induce regulatoryT cells and suppress anti-islet autoimmunity in NOD mice

Arai T, Moriyama H, Shimizu M, Sasaki H, Kishi M, Okumachi Y,Yasuda H, Hara K, Yokono K, Nagata M

2010 33 J Neurochem 2010 07 114 2 627 638GABA modulates development of cerebellar Purkinje cell dendritesunder control of endocannabinoid signaling

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2010 34 Arch Biochem Biophys 2010 06 498 1 35 42The CagA protein of Helicobacter pylori suppresses the functions ofdendritic cell in mice

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2010 35 Toxicol Sci 2010 06 115 2 482 912,3,7,8-tetrachlorodibenzo-p-dioxin impairs an insulin signalingpathway through the induction of tumor necrosis factor-alpha in

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2010 36 Dev Dyn 2010 06 239 6 1789 1796Expression of strawberry notch family genes during zebrafishembryogenesis

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2010 37 Tissue Eng Part C Methods 2010 06 16 3 347 53Nondestructive Evaluation of Cell Numbers in Bone Marrow StromalCells /beta-tricalcium phosphate Composites Using Ultrasound

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2010 38Int J Clin Rheumatol 2010 06 5 6 619 626

The cause of systemic lupus erythematosus: implication of ‘self-organized criticality theory of autoimmunity’ on the pathogenesis ofsystemic lupus erythematosus

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2010 39Circ Res 2010 06 106 11 1731 42

Role of afadin in vascular endothelial growth factor- and sphingosine1-phosphate-induced angiogenesis

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2010 40Circulation 2010 06 121 22 2407 18

Endothelial cell-derived endothelin-1 promotes cardiac fibrosis indiabetic hearts through stimulation of endothelial-to-mesenchymaltransition

Widyantoro B, Emoto N, Nakayama K, Anggrahini DW, Adiarto S,Iwasa N, Yagi K, Miyagawa K, Rikitake Y, Suzuki T, Kisanuki YY,Yanagisawa M, Hirata K

2010 41 Surg Today 2010 05 40 5 470 3Mucinous cystic neoplasm of the pancreas presenting withhemosuccus pancreaticus: report of a case

Shinzeki M, Hori Y, Fujino Y, Matsumoto I, Toyama H, TsujimuraT, Sakai T, Ajiki T, Kuroda Y, Ku Y

2010 42 Clin Exp Immunol 2010 05 160 2 283 92Vitamin K3 attenuates lipopolysaccharide-induced acute lung injurythrough inhibition of nuclear factor-kappaB activation

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2010 43Int J Mol Med 2010 05 25 5 761 7

Monoacetylcurcumin strongly regulates inflammatory responsesthrough inhibition of NF-kappaB activation

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2010 44 Perfusion 2010 05 25 3 159 68Controlled low-flow reperfusion after warm brain ischemia reducesreperfusion injury in canine model

Munakata H, Okada K, Hasegawa T, Hino Y, Kano H, MatsumoriM, Okita Y

2010 45 Proc Natl Acad Sci U S A 2010 04 107 15 6765 70Key roles for MED1 LxxLL motifs in pubertal mammary glanddevelopment and luminal-cell differentiation

Jiang P, Hu Q, Ito M, Meyer S, Waltz S, Khan S, Roeder RG,Zhang X

2010 46 Biochem Biophys Res Commun 2010 03Regulatory CD8+ T cells induced by exposure to all-trans retinoicacid and TGF-beta suppress autoimmune diabetes

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2010 47 Infect Immun 2010 03 78 6 2653 66IFN-{gamma} produced by antigen-specific CD4 T cells regulates themucosal immune responses to Citrobacter rodentium infection

Shiomi H, Masuda A, Nishiumi S, Nishida M, Takagawa T, ShiomiY, Kutsumi H, Blumberg RS, Azuma T, Yoshida M

2010 48 J Immunol 2010 03 184 5 2337 47Anti-Programmed Cell Death 1 Antibody Reduces CD4 PD-1 T Cellsand Relieves the Lupus-Like Nephritis of NZB/W F1 Mice

Kasagi S, Kawano S, Okazaki T, Honjo T, Morinobu A, Hatachi S,Shimatani K, Tanaka Y, Minato N, Kumagai S

2010 49 Neurosci Res 2010 03 66 3 321 9Development of the somatosensory cortex, the cerebellum, and themain olfactory system in Semaphorin 3F knockout mice

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2010 50 Arthroscopy 2010 03 26 3 375 383Electrospun Synthetic Polymer Scaffold for Cartilage Repair WithoutCultured Cells in an Animal Model

Toyokawa N, Fujioka H, Kokubu T, Nagura I, Inui A, Sakata R,Satake M, Kaneko H, Kurosaka M

2010 51Hypertension 2010 03 55 3 738 46

Attenuation of Doxorubicin-induced cardiomyopathy by endothelin-converting enzyme-1 ablation through prevention of mitochondrialbiogenesis impairment

Miyagawa K, Emoto N, Widyantoro B, Nakayama K, Yagi K,Rikitake Y, Suzuki T, Hirata K

2010 52Endocrinology 2010 03 151 3 971 9

An increase in the circulating concentration of monocytechemoattractant protein-1 elicits systemic insulin resistanceirrespective of adipose tissue inflammation in mice

Tateya S, Tamori Y, Kawaguchi T, Kanda H, Kasuga M

2010 53 Am J Nephrol 2010 03 31 4 342 352Oxidative and Nitrosative Stress and Progression of DiabeticNephropathy in Type 2 Diabetes

Fujii H, Kono K, Nakai K, Goto S, Komaba H, Hamada Y,Shinohara M, Kitazawa R, Kitazawa S, Fukagawa M

2010 54J Pharmacol Exp Ther 2010 02 332 2 541 8

Lipoxin A(4) reduces lipopolysaccharide-induced inflammation inmacrophages and intestinal epithelial cells through inhibition ofnuclear factor-kappaB activation

Kure I, Nishiumi S, Nishitani Y, Tanoue T, Ishida T, Mizuno M,Fujita T, Kutsumi H, Arita M, Azuma T, Yoshida M

2010 55Kobe J Med Sci 2010 02 55 4 E82 E92

A transgenic mouse line with a 58-kb fragment deletion inchromosome 11E1 that encompasses part of the Fam20a gene and itsupstream region shows growth disorder

An C, Ide Y, Nagano-Fujii M, Kitazawa S, Shoji I, Hotta H

2010 56 J Orthop Res 2010 02Matrix metalloproteinase (MMP)-3 gene up-regulation in a rat tailcompression loading-induced disc degeneration model

Yurube T, Nishida K, Suzuki T, Kaneyama S, Zhang Z, KakutaniK, Maeno K, Takada T, Fujii M, Kurosaka M, Doita M

2010 57 Microvasc Res 2010 02Role of endothelial cell-selective adhesion molecule inhematogeneous metastasis

Cangara HM, Ishida T, Hara T, Sun L, Toh R, Rikitake Y, KunduRK, Quertermous T, Hirata KI, Hayashi Y

2010 58Muscle Nerve 2010 02

Branched-chain amino acids protect against dexamethasone-inducedsoleus muscle atrophy in rats

Yamamoto D, Maki T, Herningtyas EH, Ikeshita N, Shibahara H,Sugiyama Y, Nakanishi S, Iida K, Iguchi G, Takahashi Y, Kaji H,Chihara K, Okimura Y

2010 59 Kobe J Med Sci 2010 02 55 4 E98 105 Effects of calcium phosphate cement on the peripheral nerve fibersMunemoto S, Shibuya Y, Murata M, Takeuchi J, Ikehata N,Kobayashi M, Suzuki H, Umeda M, Komori T

2010 60 Dev Growth Differ 2010 02 52 2 181 93Dispersion of the neurons expressing layer specific markers in thereeler brain

Dekimoto H, Terashima T, Katsuyama Y

2010 61 J Immunol 2010 02 184 3 1560 5Mammalian clock gene Cryptochrome regulates arthritis viaproinflammatory cytokine TNF-alpha

Hashiramoto A, Yamane T, Tsumiyama K, Yoshida K, Komai K,Yamada H, Yamazaki F, Doi M, Okamura H, Shiozawa S

2010 62 Pulm Pharmacol Ther 2010 02 23 1 36 42Sphingosine kinase 1 regulates mucin production via ERKphosphorylation

Kono Y, Nishiuma T, Okada T, Kobayashi K, Funada Y, Kotani Y,Jahangeer S, Nakamura S, Nishimura Y

2010 63Inflamm Bowel Dis 2010 01 16 1 87 95

Resolvin E1, an endogenous lipid mediator derived fromeicosapentaenoic acid, prevents dextran sulfate sodium-inducedcolitis

Ishida T, Yoshida M, Arita M, Nishitani Y, Nishiumi S, Masuda A,Mizuno S, Takagawa T, Morita Y, Kutsumi H, Inokuchi H, SerhanCN, Blumberg RS, Azuma T

2010 64 Exp Eye Res 2010 01 90 1 17 25Altered expression of aquaporins 1 and 4 coincides withneurodegenerative events in retinas of spontaneously diabetic Torii

Fukuda M, Nakanishi Y, Fuse M, Yokoi N, Hamada Y, FukagawaM, Negi A, Nakamura M

2010 65 Cardiovasc Res 2010 01Pitavastatin decreases the expression of endothelial lipase both invitro and in vivo

Kojima Y, Ishida T, Sun L, Yasuda T, Toh R, Rikitake Y, FukudaA, Kume N, Koshiyama H, Taniguchi A, Hirata KI

2010 66Int J Oral Maxillofac Surg 2010 01 39 1 42 9

The influence of surgical procedure and the effect of chemotherapyon nodal and distant metastases of human malignant melanomas thathave been grafted into nude mice

Oguni A, Umeda M, Shigeta T, Takahashi H, Komori T

2010 67 Dev Dyn 2010 01 239 1 1 15Ror-family receptor tyrosine kinases in noncanonical Wnt signaling:their implications in developmental morphogenesis and human

Minami Y, Oishi I, Endo M, Nishita M

2010 68

J Clin Invest 2010 01 120 1 115 26Ablation of C/EBPbeta alleviates ER stress and pancreatic beta cellfailure through the GRP78 chaperone in mice

Matsuda T, Kido Y, Asahara S, Kaisho T, Tanaka T, Hashimoto N,Shigeyama Y, Takeda A, Inoue T, Shibutani Y, Koyanagi M,Hosooka T, Matsumoto M, Inoue H, Uchida T, Koike M, UchiyamaY, Akira S, Kasuga M

2010 69 Am J Physiol Endocrinol Metab 2010 01PDK1/ FoxO1 pathway in POMC neurons regulates Pomc expressionand food intake

Iskandar K, Cao Y, Hayashi Y, Nakata M, Takano E, Yada T,Zhang C, Ogawa W M D, Oki M, Chua S Jr, Itoh H, Noda T,

2010 70J Immunol 2010 01 184 2 993 1002

Crucial role of phospholipase Cepsilon in induction of local skininflammatory reactions in the elicitation stage of allergic contacthypersensitivity

Hu L, Edamatsu H, Takenaka N, Ikuta S, Kataoka T

2010 71 J DIABETES INVEST 2010 00 1 6 242 251 Tracing phenotypic reversibility of pancreatic β-cells in vitro Minami K, Miyawaki K, Hara M, Yamada S, and Seino S

2010 72 Neurol Med Chir (Tokyo) 2010 00 50 2 158 61 Solitary metastatic tumor within the optic chiasm Arai A, Morishita A, Hanada Y, Aihara H

2010 73 J DIABETES INVEST 2010 00 1 4 137 142Establishment of new clonal pancreatic bta-cell lines (MIN6-K) usefulfor study of incretin/cAMP signaling

Iwasaki M, Minami K, Shibasaki T, Miki T, Miyazaki J-I, and SeinoS

2010 74 骨折 2010 12 324

号679 681

舟状骨偽関節に伴う変形性手関節症に対する部分手関節固定術の治療成績

乾淳幸, 藤岡宏幸, 坂田亮介, 豊川成和, 名倉一成, 国分毅, 牧野健, 黒坂昌弘

2010 75 医道の日本 2010 11 6911号

81 85 鍼の治効機序研究の新展開 高岡　裕

2010 76癌と化学療法 2010 11 37

12号

2804 2806スペーサー手術と粒子線治療による2段階治療が有効であった仙骨脊索腫の1例

高橋応典, 福本巧, 楠信也, 土田忍, 木戸正浩, 武部敦志, 粟津正英, 片岡庸子, 松本逸平, 味木徹夫, 堀裕一, 鈴木知志, 黒田大介, 村上昌雄, 菱川良夫, 具英成

2010 77 臨床免疫・アレルギー科 2010 11 545

号583 587 アレルギー性気道炎症におけるIgGとFc受容体を介したはたらき 山本正嗣, 小林和幸, 西村善博

2010 78 癌と化学療法 2010 11 3712号

2300 2302肝切除と経皮的肝灌流(PIHP)の2段階治療(Dual Tx)が奏効したVp4門脈腫瘍栓(PVTT)を伴う肝細胞癌(HCC)の1例

中馬正志, 福本巧, 楠信也, 土田忍, 木戸正浩, 高橋応典, 津川大介, 粟津正英, 片岡庸子, 松本逸平, 堀裕一, 黒田大介, 具英成

2010 79癌と化学療法 2010 11 37

12号

2312 2314肝細胞癌術後リンパ節再発に対しリンパ節切除術と経皮的肝灌流化学療法を施行し長期生存を得た1例

津川大介, 福本巧, 楠信也, 土田忍, 千堂宏義, 木戸正浩, 高橋応典, 武部敦志, 粟津正英, 片岡庸子, 松本逸平, 味木徹夫, 堀裕一, 鈴木知志, 黒田大介, 具英成

2010 80

日本臨床 2010 10

別冊肝・

胆道系症候

175 177【肝・胆道系症候群(第2版)　その他の肝・胆道系疾患を含めて】　肝臓編 肝細胞癌以外の肝腫瘍　境界領域型腺腫様過形成

木下秘我, 堀裕一, 具英成

2010 81 神緑会学術誌 2010 8 26 75 76 椎間板変性機序の解明と新たな治療戦略に関する研究 由留部崇, 土井田稔, 黒坂昌弘

2010 82 臨床免疫・アレルギー科 2010 7 541

号65 71

【アレルギー疾患と脂質メディエーター】 スフィンゴシン1リン酸代謝と気管支喘息

西馬照明, 西村善博

2010 83日本マイクロサージャリー学会会誌

2010 6 232

号153 153 新しい脱細胞化技術による代替小口径血管・末梢神経の開発 榊原俊介, 石田泰久, 橋川和信, 寺師浩人, 田原真也

2010 84 分子消化器病 2010 6 72

号169 173

シグナル伝達を理解するために必要な知識(第26回)(No.51)　細胞間接着分子ネクチンを介したシグナル伝達

小林一葵, 吉田優, 西田真之, 東健

2010 85 日本消化器外科学会雑誌 2010 5 435

号548 553

膵頭十二指腸切除術後の上腸間膜動脈仮性動脈瘤出血に対し動脈バイパス術を施行し救命しえた1例

椋棒英世, 松本逸平, 白川幸代, 外山博近, 新関亮, 辻村敏明,味木徹夫, 堀裕一, 福本巧, 具英成

2010 86 頭頸部自律神経 2010 3 24 37 39メチマゾール投与嗅神経細胞障害モデルにおける嗅球内遺伝子発現の検討

浦長瀬昌宏, 土井清司, 丹生健一

2010 87 医科学応用研究財団研究報告 2010 2 27 211 215 EPA由来生理活性物質のDSS腸炎に対する腸炎抑制効果の検討 吉田優, 東健, 石田司

2009 1 Int Orthop 2009 12Potency of double-layered Poly L-lactic Acid scaffold in tissueengineering of tendon tissue

Inui A, Kokubu T, Makino T, Nagura I, Toyokawa N, Sakata R,Kotera M, Nishino T, Fujioka H, Kurosaka M

2009 2 PLoS One 2009 12 4 12 e8382 e8382 Self-organized criticality theory of autoimmunity Tsumiyama K, Miyazaki Y, Shiozawa S

2009 3 Biomed Res 2009 12 30 6 325 30Effect of intrauterine undernutrition during late gestation onpancreatic beta cell mass

Inoue T, Kido Y, Asahara S, Matsuda T, Shibutani Y, Koyanagi M,Kasuga M

2009 4 J Atheroscler Thromb 2009 12 16 6 846 856RhoA and Rac1 Changes in the Atherosclerotic Lesions of WHHLMIRabbits

Ohkawara H, Ishibashi T, Shiomi M, Sugimoto K, Uekita H,Kamioka M, Takuwa Y, Teramoto T, Maruyama Y, Takeishi Y

2009 5 J Vasc Surg 2009 12 50 6 1423 32A novel rat model of abdominal aortic aneurysm using a combinationof intraluminal elastase infusion and extraluminal calcium chloride

Tanaka A, Hasegawa T, Chen Z, Okita Y, Okada K

2009 6 Atherosclerosis 2009 11 207 1 1 7The Watanabe heritable hyperlipidemic (WHHL) rabbit, itscharacteristics and history of development: a tribute to the late Dr.

Shiomi M, Ito T

2009 7 Circulation 2009 11 120 20 1996 2005Oral anti-CD3 antibody treatment induces regulatory T cells andinhibits the development of atherosclerosis in mice

Sasaki N, Yamashita T, Takeda M, Shinohara M, Nakajima K,Tawa H, Usui T, Hirata K

2009 8 J Thorac Cardiovasc Surg 2009 11Augmentation of systemic blood pressure during spinal cord ischemiato prevent postoperative paraplegia after aortic surgery in a rabbit

Izumi S, Okada K, Hasegawa T, Omura A, Munakata H,Matsumori M, Okita Y

2009 9Hypertension 2009 10 54 4 825 31

Deficiency of nectin-2 leads to cardiac fibrosis and dysfunction underchronic pressure overload

Satomi-Kobayashi S, Ueyama T, Mueller S, Toh R, Masano T,Sakoda T, Rikitake Y, Miyoshi J, Matsubara H, Oh H, KawashimaS, Hirata K, Takai Y

2009 10 Biochem Biophys Res Commun 2009 10 387 4 754 9Impaired vascular development in the yolk sac and allantois in micelacking RA-GEF-1

Kanemura H, Satoh T, Bilasy SE, Ueda S, Hirashima M, KataokaT

2009 11 J Invest Dermatol 2009 10Agents that Reverse UV-Induced Immune Suppression andPhotocarcinogenesis Affect DNA Repair

Sreevidya CS, Fukunaga A, Khaskhely NM, Masaki T, Ono R,Nishigori C, Ullrich SE

2009 12 Shock 2009 10 32 4 401 9Gender difference in granulocyte dynamics and apoptosis and the roleof IL-18 during endotoxin-induced systemic inflammation

Aoyama M, Kotani J, Usami M

2009 13Graefes Arch Clin ExpOphthalmol

2009 10 247 10 1353 60Tafluprost protects rat retinal ganglion cells from apoptosis in vitroand in vivo

Kanamori A, Naka M, Fukuda M, Nakamura M, Negi A

2009 14 J Thorac Cardiovasc Surg 2009 09 138 3 744 51Renoprotective immunosuppression by pioglitazone with low-dosecyclosporine in rat heart transplantation

Tanaka Y, Hasegawa T, Chen Z, Okita Y, Okada K

2009 15 Mol Vis 2009 09 15 1764 73RNA interference for apoptosis signal-regulating kinase-1 (ASK-1)rescues photoreceptor death in the rd1 mouse

Sekimukai D, Honda S, Negi A

2009 16 Int J Cancer 2009 09 125 6 1407 13MicroRNA-10b is overexpressed in malignant glioma and associatedwith tumor invasive factors, uPAR and RhoC

Sasayama T, Nishihara M, Kondoh T, Hosoda K, Kohmura E

2009 17 Anat Sci Int 2009 09 84 3 200 9Histological study in the brain of the reelin/Dab1-compound mutantmouse

Yamamoto T, Setsu T, Okuyama-Yamamoto A, Terashima T

2009 18

Evid Based Complement AlternatMed

2009 08Full-length sequence of mouse acupuncture-induced 1-L (Aig1l) geneincluding its transcriptional start site

Ohta M, Sugano A, Goto S, Yusoff S, Hirota Y, Funakoshi K,Miura K, Maeda E, Takaoka N, Sato N, Ishizuka H, Arizono N,Nishio H, Takaoka Y

2009 19 Dig Dis Sci 2009 08 54 8 1625 35Alterations in gastric mucosal lineages before or after acute oxynticatrophy in gastrin receptor and H2 histamine receptor-deficient mice

Aikou S, Fukushima Y, Ogawa M, Nozaki K, Saito T, Matsui T,Goldenring JR, Kaminishi M, Nomura S

2009 20J Comp Neurol 2009 08 515 5 565 84

Fezf1 is required for penetration of the basal lamina by olfactoryaxons to promote olfactory development

Watanabe Y, Inoue K, Okuyama-Yamamoto A, Nakai N, NakataniJ, Nibu K, Sato N, Iiboshi Y, Yusa K, Kondoh G, Takeda J,Terashima T, Takumi T

2009 21 Brain Res 2009 08 1283 186 93Expression of ATP-binding cassette transporters at the inner blood-retinal barrier in a neonatal mouse model of oxygen-induced

Tagami M, Kusuhara S, Honda S, Tsukahara Y, Negi A

2009 22 Carcinogenesis 2009 08 30 8 1424 32Phospholipase Cepsilon promotes intestinal tumorigenesis ofApc(Min/ ) mice through augmentation of inflammation and

Li M, Edamatsu H, Kitazawa R, Kitazawa S, Kataoka T

2009 23 Orthopedics 2009 08 32Ankle arthrodesis using antegrade intramedullary nail for salvage ofnonreconstructable tibial pilon fractures

Niikura T, Miwa M, Sakai Y, Lee SY, Oe K, Iwakura T, Koh A,Koga T, Kurosaka M

2009 24 Biochem Biophys Res Commun 2009 08 385 4 539 44Involvement of afadin in the formation and remodeling of synapses inthe hippocampus

Majima T, Ogita H, Yamada T, Amano H, Togashi H, Sakisaka T,Tanaka-Okamoto M, Ishizaki H, Miyoshi J, Takai Y

2009 25 J Atheroscler Thromb 2009 08 16 4 327 38Role of endothelial lipase in plasma HDL levels in a murine model ofhypertriglyceridemia

Tanaka H, Ishida T, Johnston TP, Yasuda T, Ueyama T, KojimaY, Kundu RK, Quertermous T, Ishikawa Y, Hirata K

2009 26Oncol Rep 2009 08 22 2 337 43

Enhancement of anti-tumor immunity by high levels of Th1 and Th17with a combination of dendritic cell fusion hybrids and regulatory Tcell depletion in pancreatic cancer

Yamamoto M, Kamigaki T, Yamashita K, Hori Y, Hasegawa H,Kuroda D, Moriyama H, Nagata M, Ku Y, Kuroda Y

2009 27 Andrologia 2009 08 41 4 216 21Experimental ischaemia-reperfusion injury induces vascularendothelial growth factor expression in the rat testis

Hashimoto H, Ishikawa T, Yamaguchi K, Shiotani M, Fujisawa M

2009 28 Science 2009 07 325 5940 607 10The cAMP sensor Epac2 is a direct target of antidiabetic sulfonylureadrugs

Zhang CL, Katoh M, Shibasaki T, Minami K, Sunaga Y, TakahashiH, Yokoi N, Iwasaki M, Miki T, Seino S

2009 29 Int J Cancer 2009 07 125 2 328 38BAMBI gene is epigenetically silenced in subset of high-grade bladdercancer

Khin SS, Kitazawa R, Win N, Aye TT, Mori K, Kondo T, KitazawaS

2009 30 Int Orthop 2009 06 33 3 821 8The effect of porosity and mechanical property of a synthetic polymerscaffold on repair of osteochondral defects

Ikeda R, Fujioka H, Nagura I, Kokubu T, Toyokawa N, Inui A,Makino T, Kaneko H, Doita M, Kurosaka M

2009 31 BJU Int 2009 06 103 11 1569 73Modulation of the microenvironment by growth factors regulates thein vivo growth of skeletal myoblasts

Yanagiuchi A, Miyake H, Nomi M, Takenaka A, Fujisawa M

2009 32 Mol Cancer Res 2009 06 7 6 880 9Inhibition of G(1) to S phase progression by a novel zinc finger proteinP58(TFL) at P-bodies

Minagawa K, Katayama Y, Nishikawa S, Yamamoto K, Sada A,Okamura A, Shimoyama M, Matsui T

2009 33Vaccine 2009 06 27 28 3735 43

A simple method for evaluating dengue vaccine effectiveness in micebased on levels of viremia caused by intraperitoneal injection ofinfected culture cells

Yamanaka A, Konishi E

2009 34Development 2009 06 136 12 2049 58

Inhibitory and excitatory subtypes of cochlear nucleus neurons aredefined by distinct bHLH transcription factors, Ptf1a and Atoh1

Fujiyama T, Yamada M, Terao M, Terashima T, Hioki H, Inoue YU,Inoue T, Masuyama N, Obata K, Yanagawa Y, Kawaguchi Y,Nabeshima Y, Hoshino M

2009 35

Endocrinology 2009 06 150 6 2683 91Muscle-specific overexpression of heparin-binding epidermal growthfactor-like growth factor increases peripheral glucose disposal andinsulin sensitivity

Fukatsu Y, Noguchi T, Hosooka T, Ogura T, Kotani K, Abe T,Shibakusa T, Inoue K, Sakai M, Tobimatsu K, Inagaki K, YoshiokaT, Matsuo M, Nakae J, Matsuki Y, Hiramatsu R, Kaku K, OkamuraH, Fushiki T, Kasuga M

2009 36Diabetes 2009 06 58 6 1321 32

Upregulation of the mammalian target of rapamycin complex 1pathway by Ras homolog enriched in brain in pancreatic beta-cellsleads to increased beta-cell mass and prevention of hyperglycemia

Hamada S, Hara K, Hamada T, Yasuda H, Moriyama H, NakayamaR, Nagata M, Yokono K

2009 37 Antioxid Redox Signal 2009 06 11 6 1227 35Thioredoxin Suppresses the Contact Hypersensitivity Response byInhibiting Leukocyte Recruitment during the Elicitation Phase

Fukunaga A, Horikawa T, Ogura K, Taguchi K, Xijun Y, FunasakaY, Takeda M, Nakamura H, Yodoi J, Nishigori C

2009 38 J Invest Dermatol 2009 05 129 5 1225 1231 Molecular Clocks in Mouse SkinTanioka M, Yamada H, Doi M, Bando H, Yamaguchi Y, Nishigori C,Okamura H

2009 39Circ J 2009 05 73 5 955 62

Plasma tetrahydrobiopterin/dihydrobiopterin ratio: a possible markerof endothelial dysfunction

Takeda M, Yamashita T, Shinohara M, Sasaki N, Takaya T,Nakajima K, Inoue N, Masano T, Tawa H, Satomi-Kobayashi S,Toh R, Sugiyama D, Nishimura K, Yokoyama M, Hirata KI,

2009 40 Br J Cancer 2009 05 100 9 1438 43Hypermethylation-mediated reduction of WWOX expression inintraductal papillary mucinous neoplasms of the pancreas

Nakayama S, Semba S, Maeda N, Matsushita M, Kuroda Y,Yokozaki H

2009 41 Cardiovasc Res 2009 05 82 2 371 81RAGE mediates oxidized LDL-induced pro-inflammatory effects andatherosclerosis in non-diabetic LDL receptor-deficient mice

Sun L, Ishida T, Yasuda T, Kojima Y, Honjo T, Yamamoto Y,Yamamoto H, Ishibashi S, Hirata K, Hayashi Y

2009 42 Microvasc Res 2009 05 77 3 348 55Endothelial cell-selective adhesion molecule regulates albuminuria indiabetic nephropathy

Hara T, Ishida T, Cangara HM, Hirata K

2009 43 Eur J Neurosci 2009 05 29 10 1994 2008Dorsal telencephalon-specific RA-GEF-1 knockout mice developheterotopic cortical mass and commissural fiber defect

Bilasy SE, Satoh T, Ueda S, Wei P, Kanemura H, Aiba A,Terashima T, Kataoka T

2009 44Bone 2009 05 44 5 936 41

Thioredoxin-1 overexpression in transgenic mice attenuatesstreptozotocin-induced diabetic osteopenia: A novel role of oxidativestress and therapeutic implications

Hamada Y, Fujii H, Kitazawa R, Yodoi J, Kitazawa S, Fukagawa M

2009 45 Neuroreport 2009 05 20 8 764 9Effect of intranasal administration of basic fibroblast growth factor onolfactory epithelium

Nishikawa T, Doi K, Ochi N, Katsunuma S, Nibu K

2009 46 Cell Cycle 2009 05 8 10 1539 43 Pathogenesis of rheumatoid arthritis and c-Fos/AP-1 Shiozawa S, Tsumiyama K

2009 47

Am J Physiol Lung Cell MolPhysiol

2009 04 296 4 L594 602Targeted inactivation of endothelial lipase attenuates lung allergicinflammation through raising plasma HDL level and inhibiting eosinophilinfiltration

Otera H, Ishida T, Nishiuma T, Kobayashi K, Kotani Y, Yasuda T,Kundu RK, Quertermous T, Hirata K, Nishimura Y

2009 48 Cardiovasc Res 2009 04 82 1 143 51Vascular endothelial cell-derived endothelin-1 mediates vascularinflammation and neointima formation following blood flow cessation

Anggrahini DW, Emoto N, Nakayama K, Widyantoro B, Adiarto S,Iwasa N, Nonaka H, Rikitake Y, Kisanuki YY, Yanagisawa M,

2009 49 Biochem Biophys Res Commun 2009 04 381 3 367 71Increased ribosomal biogenesis induces pancreatic beta cell failure inmice model of type 2 diabetes

Asahara S, Matsuda T, Kido Y, Kasuga M

2009 50

Microbes Infect 2009 04 11 4 467 75

Single-point mutations of the M protein of a measles virus variantobtained from a patient with subacute sclerosing panencephalitiscritically affect solubility and subcellular localization of the M proteinand cell-free virus production

Jiang DP, Ide YH, Nagano-Fujii M, Shoji I, Hotta H

2009 51 Dev Growth Differ 2009 04 51 3 271 86 Developmental anatomy of reeler mutant mouse Katsuyama Y, Terashima T

2009 52 Urology 2009 04 73 4 906 10Downregulation of lectin-like oxidized low-density lipoproteinreceptor-1 after ischemic preconditioning in ischemia-reperfused rat

Hyodo Y, Miyake H, Kondo Y, Fujisawa M

2009 53Graefes Arch Clin ExpOphthalmol

2009 04 247 4 515 22Anti-angiogenic effects of non-peptide integrin alphavbeta3 specificantagonist on laser-induced choroidal neovascularization in mice

Honda S, Nagai T, Negi A

2009 54 Inflamm Allergy Drug Targets 2009 03 8 1 80 6 Role of Fc Receptors as a therapeutic targetMasuda A, Yoshida M, Shiomi H, Morita Y, Kutsumi H, Inokuchi H,Mizuno S, Nakamura A, Takai T, Blumberg RS, Azuma T

2009 55 Kobe J Med Sci 2009 03 54 6 E264 71Role of angiotensin and the clock system in the circadian regulation ofplasminogen activator inhibitor-1

Masuda Y, Emoto N, Nonaka H, Yagita K, Todo T, Okamura H,Yokoyama M, Hirata K

2009 56Oral Surg Oral Med Oral PatholOral Radiol Endod

2009 03 107 3 398 406Ror2 expression in squamous cell carcinoma and epithelial dysplasiaof the oral cavity

Kobayashi M, Shibuya Y, Takeuchi J, Murata M, Suzuki H, YokooS, Umeda M, Minami Y, Komori T

2009 57 Kobe J Med Sci 2009 03 54 6 E279 89The simultaneous induction of tumorigenesis and Cre-loxPrecombination in mice

Sakahara M, Ohkawara H, Nakao K, Yokozaki H, Aiba A

2009 58Arch Otolaryngol Head NeckSurg

2009 03 135 3 282 6Cyclooxygenase 2 promoter-based replication-selective adenoviralvector for hypopharyngeal cancer

Nakagawa T, Tanaka H, Shirakawa T, Gotoh A, Hayashi Y,Hamada K, Tsukuda M, Nibu K

2009 59

Microvasc Res 2009 03 77 2 230 3

Dilation of perforating arteries in rat brain in response to systemichypotension is more sensitive and pronounced than that of pialarterioles Simultaneous visualization of perforating and corticalvessels by in-vivo microangiography

Yoshino H, Sakurai T, Oizumi XS, Akisaki T, Wang X, Yokono K,Kondoh T, Kohmura E, Umentani K

2009 60 Exp Eye Res 2009 03 88 3 535 41Latanoprost protects rat retinal ganglion cells from apoptosis in vitroand in vivo

Kanamori A, Naka M, Fukuda M, Nakamura M, Negi A

2009 61Am J Physiol Lung Cell MolPhysiol

2009 03 296 3 L337 46Inhalation of urokinase-type plasminogen activator reduces airwayremodeling in a murine asthma model

Kuramoto E, Nishiuma T, Kobayashi K, Yamamoto M, Kono Y,Funada Y, Kotani Y, Sisson TH, Simon RH, Nishimura Y

2009 62 Biomed Res 2009 02 30 1 39 45Influence of muscle length on muscle atrophy in the mouse tibialisanterior and soleus muscles

Fujita N, Fujimoto T, Tasaki H, Arakawa T, Matsubara T, Miki A

2009 63 Nephrol Dial Transplant 2009 02 24 7 2089 2095Oral charcoal adsorbent (AST-120) prevents progression of cardiacdamage in chronic kidney disease through suppression of oxidative

Fujii H, Nishijima F, Goto S, Sugano M, Yamato H, Kitazawa R,Kitazawa S, Fukagawa M

2009 64 J Mol Endocrinol 2009 02 42 2 161 9Role of the E3 ubiquitin ligase gene related to anergy in lymphocytesin glucose and lipid metabolism in the liver

Nakamichi S, Senga Y, Inoue H, Emi A, Matsuki Y, Watanabe E,Hiramatsu R, Ogawa W, Kasuga M

2009 65 Diabetes Res Clin Pract 2009 02 83 2 200 7NO-mediated cytotoxicity contributes to multiple low-dosestreptozotocin-induced diabetes but not to NOD diabetes

Yasuda H, Jin Z, Nakayama M, Yamada K, Kishi M, Okumachi Y,Arai T, Moriyama H, Yokono K, Nagata M

2009 66 J Bone Joint Surg Br 2009 02 91 2 264 70Osteogenic activity of human fracture haematoma-derived progenitorcells is stimulated by low-intensity pulsed ultrasound in vitro

Hasegawa T, Miwa M, Sakai Y, Niikura T, Kurosaka M, Komori T

2009 67 J Orthop Res 2009 02 27 2 208 15Human hypertrophic nonunion tissue contains mesenchymalprogenitor cells with multilineage capacity in vitro

Iwakura T, Miwa M, Sakai Y, Niikura T, Lee SY, Oe K, HasegawaT, Kuroda R, Fujioka H, Doita M, Kurosaka M

2009 68 Int Orthop 2009 02 33 1 275 80The effect of fibroblast growth factor-2 on autologous osteochondraltransplantation

Nakayama J, Fujioka H, Nagura I, Kokubu T, Makino T, Kuroda R,Tabata Y, Kurosaka M

2009 69 Neuroimage 2009 02 44 4 1274 83In vivo and in vitro visualization of gene expression dynamics overextensive areas of the brain

Eguchi M, Yamaguchi S

2009 70 Eur Spine J 2009 02 18 2 263 70Sustained long-term RNA interference in nucleus pulposus cells invivo mediated by unmodified small interfering RNA

Suzuki T, Nishida K, Kakutani K, Maeno K, Yurube T, Takada T,Kurosaka M, Doita M

2009 71 J Physiol Sci 2009 01 59 1 23 9Gastric acid secretion in cholecystokinin-1 receptor, -2 receptor, and-1, -2 receptor gene knockout mice

Kanai S, Hosoya H, Akimoto S, Ohta M, Matsui T, Takiguchi S,Funakoshi A, Miyasaka K

2009 72 Kobe J Med Sci 2009 01 54 4 E217 26Expression of beta-catenin and integrin-linked kinase in the mousesciatic nerve

Takeuchi J, Shibuya Y, Murata M, Komori T

2009 73 J Urol 2009 01 181 1 372 378The impact of decreasing urinary IgA levels on decreased bacteriuriain a rat model of ileal augmented bladder

Miura T, Tanaka K, Nakano Y, Arakawa S, Takenaka A, FujisawaM

2009 74 日本消化器外科学会雑誌 2009 12 4212号

1831 1836下大静脈腫瘍栓を伴った切除不能大腸癌肝転移に対してスペーサー留置術および陽子線照射による2段階治療が奏効した1例

小松昇平, 福本巧, 堀裕一, 村上昌雄, 菱川良夫, 具英成

2009 75 神緑会学術誌 2009 8 25 66 68 腰痛のメカニズムの解明と治療に関する研究高田徹, 西田康太郎, 前野耕一郎, 角谷賢一朗, 土井田稔, 黒坂昌弘

2009 76 The Lipid 2009 7 203

号312 318 【脂溶性シグナル分子と疾患】 ω3多価不飽和脂肪酸と炎症性腸疾患 吉田優, 石田司, 西田真之, 西海信, 東健, 有田誠

2009 77日本マイクロサージャリー学会会誌

2009 6 222

号92 93

神経の変則的縫合術 移植床神経による筋(皮)弁の「再支配」　ラットモデルを用いた脱神経萎縮防止効果の検討

橋川和信, 大守誠, 榊原俊介, 寺師浩人, 田原真也

2009 78日本マイクロサージャリー学会会誌

2009 6 222

号90 90

神経の変則的縫合術 神経トレーサーを用いる神経回路解析実験におけるわれわれの工夫

榊原俊介, 橋川和信, 寺師浩人, 田原真也, 石田泰久, 大守誠

2009 79 生化学 2009 4 814

号308 314 胎児性Fcγ受容体による細胞内トラフィックと免疫監視機構

吉田優, 増田充弘, 藤島佳未, 西海信, 水野成人, 久津見弘, 井口秀人, 東健

2009 80 日本味と匂学会誌 2009 4 16 １ 25 30 嗅神経細胞の再生研究 土井　清司

2009 81 分子消化器病 2009 3 61

号69 75

消化管上皮細胞の機能分子とその解析法　消化管上皮における免疫グロブリンレセプターの役割とその解析法

藤島佳未, 吉田優, 増田充弘, 西海信, 水野成人, 久津見弘, 東健

2009 82 Facial Nerve Research 2009 2 28 48 50順行性神経トレーサー法による神経回路解析　顔面-舌下神経cross-link手術をモデルとして

榊原俊介, 石田泰久, 橋川和信

2009 83 医科学応用研究財団研究報告 2009 2 26 155 159生活習慣病における医学、薬学の萠芽的研究 生活習慣病に合併する低HDL血症の成因における血管内皮リパーゼの関与

石田達郎

2009 84 日本集中治療医学会雑誌 2009 1 16Su

ppl.266 266

Interleukin(IL)-18はエンドトキシン(Etx)血症に伴う急性肺損傷の発症に関与する

秀野克仁, 小谷穣治, 青山倫子, 渡邉まり, 飯塚宣仁, 三好真琴,前重伯壮, 宇佐美眞, 丸川征四郎

2008 1 Curr Opin Lipidol 2008 12 19 6 631 636Unstable coronary plaques and cardiac events in myocardialinfarction-prone Watanabe heritable hyperlipidemic rabbits: questions

Shiomi M, Fan J

2008 2 J Cell Biochem 2008 12 105 5 1289 97Modulation of mouse RANKL gene expression by Runx2 and vitaminD3

Kitazawa R, Mori K, Yamaguchi A, Kondo T, Kitazawa S

2008 3 Ann N Y Acad Sci 2008 12 1150 278 81Autoreactive T cell response in CD25-negative fraction of peripheralblood mononuclear cells in established type 1 diabetes

Moriyama H, Kotani R, Katsuta A, Kameno M, Arai T, OkumachiY, Kishi M, Yamada K, Yasuda H, Hara K, Yokono K, Nagata M

2008 4Ann N Y Acad Sci 2008 12 1150 183 6

Intravenous administration of proinsulin 1 or 2-expressing fiber-mutant recombinant adenovirus vector protects against thedevelopment of diabetes in NOD mice

Yamada K, Moriyama H, Okumachi Y, Arai T, Kameno M, Kishi M,Yasuda H, Hara K, Yokono K, Nagata M

2008 5 Eur Spine J 2008 12 17 Suppl 4 459 66Gene therapy approach for disc degeneration and associated spinaldisorders

Nishida K, Suzuki T, Kakutani K, Yurube T, Maeno K, KurosakaM, Doita M

2008 6 Oncogene 2008 12 27 57 7162 70Metabotropic glutamate receptor subtype-1 is essential for in vivogrowth of melanoma

Ohtani Y, Harada T, Funasaka Y, Nakao K, Takahara C, Abdel-Daim M, Sakai N, Saito N, Nishigori C, Aiba A

2008 7 Hepatogastroenterology 2008 11 55 88 2247 51Expression of toll-like receptor 2 and 4 in intestinal mucosa inexperimental severe acute pancreatitis

Sawa H, Ueda T, Takeyama Y, Yasuda T, Shinzeki M, MatsumuraN, Nakajima T, Kuroda Y

2008 8 Behav Brain Res 2008 11 193 1 108 16Different housing conditions alter the behavioural phenotype ofCCK(2) receptor-deficient mice

Abramov U, Raud S, Innos J, Lasner H, Kurrikoff K, Tﾃｼrna T,Puussaar T, Okva K, Matsui T, Vasar E

2008 9 Stem Cells 2008 11 26 11 2912 20Enrichment of putative pancreatic progenitor cells from mice bysorting for prominin1 (CD133) and platelet-derived growth factor

Hori Y, Fukumoto M, Kuroda Y

2008 10 Biochem Biophys Res Commun 2008 11 376 3 590 4Rad9 is upregulated and plays protective roles in an acute lung injurymodel

Yamamoto M, Nishiuma T, Kobayashi K, Maniwa Y, Sakashita A,Funada Y, Kotani Y, Nishimura Y

2008 11Am J Pathol 2008 11 173 5 1326 38

Inhibition of nuclear translocation of apoptosis-inducing factor is anessential mechanism of the neuroprotective activity of pigmentepithelium-derived factor in a rat model of retinal degeneration

Murakami Y, Ikeda Y, Yonemitsu Y, Onimaru M, Nakagawa K,Kohno R, Miyazaki M, Hisatomi T, Nakamura M, Yabe T,Hasegawa M, Ishibashi T, Sueishi K

2008 12J Cell Biol 2008 10 183 2 323 37

Dual inhibition of SNARE complex formation by tomosyn ensurescontrolled neurotransmitter release

Sakisaka T, Yamamoto Y, Mochida S, Nakamura M, Nishikawa K,Ishizaki H, Okamoto-Tanaka M, Miyoshi J, Fujiyoshi Y, ManabeT, Takai Y

2008 13 J Cell Biochem 2008 10 105 3 896 904Lipopolysaccharide suppresses RANK gene expression inmacrophages by down-regulating PU.1 and MITF

Ishii J, Kitazawa R, Mori K, McHugh KP, Morii E, Kondo T,Kitazawa S

2008 14 Acta Histochem Cytochem 2008 10 41 5 135 42MeCP2 Expression and Promoter Methylation of Cyclin D1 Gene AreAssociated with Cyclin D1 Expression in Developing Rat Epididymal

Darwanto A, Kitazawa R, Mori K, Kondo T, Kitazawa S

2008 15 Biochim Biophys Acta 2008 10 1780 10 1115 20Branched-chain amino acids and arginine suppress MaFbx/atrogin-1mRNA expression via mTOR pathway in C2C12 cell line

Herningtyas EH, Okimura Y, Handayaningsih AE, Yamamoto D,Maki T, Iida K, Takahashi Y, Kaji H, Chihara K

2008 16 Kobe J Med Sci 2008 10 54 4 E200 8 Role of hepatic STAT3 in the regulation of lipid metabolismKinoshita S, Ogawa W, Okamoto Y, Takashima M, Inoue H,Matsuki Y, Watanabe E, Hiramatsu R, Kasuga M

2008 17 Kobe J Med Sci 2008 09 54 3 E183 90Pancreatic beta cell mass preserved in heterozygous PDK1 knockoutmice

Takeda A, Kido Y, Hashimoto N, Noda T, Kasuga M

2008 18Biochem Biophys Res Commun 2008 09 374 3 581 6

One amino acid difference is critical for suppression of thedevelopment of experimental autoimmune diabetes (EAD) withintravenous injection of insulinB:9-23 peptide

Okumachi Y, Moriyama H, Kameno M, Arai T, Kishi M, KuroharaM, Yamada K, Yasuda H, Hara K, Yokono K, Nagata M

2008 19Circ J 2008 09 72 9 1512 9

Beneficial effects of exogenous tetrahydrobiopterin on left ventricularremodeling after myocardial infarction in rats: the possible role ofoxidative stress caused by uncoupled endothelial nitric oxide synthase

Masano T, Kawashima S, Toh R, Satomi-Kobayashi S, ShinoharaM, Takaya T, Sasaki N, Takeda M, Tawa H, Yamashita T,Yokoyama M, Hirata K

2008 20 Mol Cell Biol 2008 09 28 17 5184 95 Increased insulin action in SKIP heterozygous knockout miceIjuin T, Yu YE, Mizutani K, Pao A, Tateya S, Tamori Y, Bradley A,Takenawa T

2008 21 Physiol Genomics 2008 09 35 1 96 105Identification of a major locus for islet inflammation and fibrosis in thespontaneously diabetic Torii rat

Fuse M, Yokoi N, Shinohara M, Masuyama T, Kitazawa R,Kitazawa S, Seino S

2008 22 Am J Sports Med 2008 08 36 8 1519 27Enhancement of tendon-bone osteointegration of anterior cruciateligament graft using granulocyte colony-stimulating factor

Sasaki K, Kuroda R, Ishida K, Kubo S, Matsumoto T, Mifune Y,Kinoshita K, Tei K, Akisue T, Tabata Y, Kurosaka M

2008 23 Acta Otolaryngol 2008 08 128 8 936 40Additive effects of oral fluoropyrimidine derivative S-1 and radiationon human hypopharyngeal cancer xenografts

Nakagawa T, Otsuki N, Masai Y, Sasaki R, Tsukuda M, Nibu K

2008 24J Thorac Imaging 2008 08 23 3 213 5 Diffuse periairway thickening in patients with Mikulicz disease

Sakashita A, Nishimura Y, Nogami M, Kuramoto E, Kono Y,Yamamoto M, Tamao N, Ohtera H, Kobayashi K, Funada Y,Nishiuma T, Kotani Y, Ohno Y

2008 25

J Clin Invest 2008 08 118 8 2808 21FSP27 contributes to efficient energy storage in murine whiteadipocytes by promoting the formation of unilocular lipid droplets

Nishino N, Tamori Y, Tateya S, Kawaguchi T, Shibakusa T,Mizunoya W, Inoue K, Kitazawa R, Kitazawa S, Matsuki Y,Hiramatsu R, Masubuchi S, Omachi A, Kimura K, Saito M, Amo T,Ohta S, Yamaguchi T, Osumi T, Cheng J, Fujimoto T, Nakao H,Nakao K, Aiba A, Okamura H, Fushiki T, Kasuga M

2008 26 Curr Eye Res 2008 08 33 8 683 92Nipradilol protects rat retinal ganglion cells from apoptosis induced byserum deprivation in vitro and by diabetes in vivo

Tatsumi Y, Kanamori A, Nagai-Kusuhara A, Nakanishi Y, AgarwalN, Negi A, Nakamura M

2008 27 Dev Cell 2008 07 15 1 23 36Cthrc1 selectively activates the planar cell polarity pathway of Wntsignaling by stabilizing the Wnt-receptor complex

Yamamoto S, Nishimura O, Misaki K, Nishita M, Minami Y,Yonemura S, Tarui H, Sasaki H

2008 28 Kobe J Med Sci 2008 07 54 2 E136 46Anti-VEGF receptor antagonist (VGA1155) reduces infarction in ratpermanent focal brain ischemia

Chiba Y, Sasayama T, Miyake S, Koyama J, Kondoh T, Hosoda K,Kohmura E

2008 29 Arthritis Rheum 2008 07 58 7 2012 8(-)-Epigallocatechin-3-gallate suppresses osteoclast differentiationand ameliorates experimental arthritis in mice

Morinobu A, Biao W, Tanaka S, Horiuchi M, Jun L, Tsuji G, SakaiY, Kurosaka M, Kumagai S

2008 30 Cancer Sci 2008 07 99 7 1370 6Role of the WWOX gene, encompassing fragile region FRA16D, insuppression of pancreatic carcinoma cells

Nakayama S, Semba S, Maeda N, Aqeilan RI, Huebner K,Yokozaki H

2008 31 Kobe J Med Sci 2008 07 54 2 E97 107The double-edged effect of insulin on the neuronal cell deathassociated with hypoglycemia on the hippocampal slice culture

Tanaka Y, Takata T, Satomi T, Sakurai T, Yokono K

2008 32Br J Pharmacol 2008 07 154 5 949 957

Lapaquistat acetate, a squalene synthase inhibitor, changesmacrophage/lipid-rich coronary plaques of hypercholesterolaemicrabbits into fibrous lesions

Shiomi M, Yamada S, Amano Y, Nishimoto T, Ito T

2008 33 Kobe J Med Sci 2008 07 54 2 E114 21Reduced insulin signaling and endoplasmic reticulum stress actsynergistically to deteriorate pancreatic beta cell function

Matsuda T, Kido Y, Uchida T, Kasuga M

2008 34 Eur J Neurosci 2008 07 28 2 257 67Rac1 in cortical projection neurons is selectively required for midlinecrossing of commissural axonal formation

Kassai H, Terashima T, Fukaya M, Nakao K, Sakahara M,Watanabe M, Aiba A

2008 35Am J Physiol Lung Cell MolPhysiol

2008 06 294 6 L1085 93Inhalation of sphingosine kinase inhibitor attenuates airwayinflammation in asthmatic mouse model

Nishiuma T, Nishimura Y, Okada T, Kuramoto E, Kotani Y,Jahangeer S, Nakamura S

2008 36 BMB Rep 2008 06 41 6 415 34 Multiple roles of phosphoinositide-specific phospholipase C isozymesSuh PG, Park JI, Manzoli L, Cocco L, Peak JC, Katan M, FukamiK, Kataoka T, Yun S, Ryu SH

2008 37Arterioscler Thromb Vasc Biol 2008 06 28 6 1068 76

Augmentation of vascular remodeling by uncoupled endothelial nitricoxide synthase in a mouse model of diabetes mellitus

Sasaki N, Yamashita T, Takaya T, Shinohara M, Shiraki R,Takeda M, Emoto N, Fukatsu A, Hayashi T, Ikemoto K, NomuraT, Yokoyama M, Hirata K, Kawashima S

2008 38 Atherosclerosis 2008 06 198 2 287 293Invasion of atheromatous plaques into tunica media causes coronaryoutward remodeling in WHHLMI rabbits

Shiomi M, Yamada S, Matsukawa A, Itabe H, Ito T

2008 39Diabetes Res Clin Pract 2008 06 80 3 352 9

Prevention of recurrent but not spontaneous autoimmune diabetes bytransplanted NOD islets adenovirally transduced withimmunomodulating molecules

Sakata M, Yasuda H, Moriyama H, Yamada K, Kotani R, KuroharaM, Okumachi Y, Kishi M, Arai T, Hara K, Hamada H, Yokono K,Nagata M

2008 40 Kobe J Med Sci 2008 05 54 1 E1 13Low-dose warfarin functions as an immunomodulator to preventcyclophosphamide-induced NOD diabetes

Kurohara M, Yasuda H, Moriyama H, Nakayama M, Sakata M,Yamada K, Kotani R, Hara K, Yokono K, Nagata M

2008 41Mol Cell Biol 2008 05 28 9 2971 9

Biphasic response of pancreatic beta-cell mass to ablation oftuberous sclerosis complex 2 in mice

Shigeyama Y, Kobayashi T, Kido Y, Hashimoto N, Asahara S,Matsuda T, Takeda A, Inoue T, Shibutani Y, Koyanagi M, UchidaT, Inoue M, Hino O, Kasuga M, Noda T

2008 42 Kobe J Med Sci 2008 05 54 1 E35 45Taurine administration after appearance of proteinuria retardsprogression of diabetic nephropathy in rats

Higo S, Miyata S, Jiang QY, Kitazawa R, Kitazawa S, Kasuga M

2008 43 Eur J Neurosci 2008 04 27 8 2147 55Stress-induced analgesia in mice: evidence for interaction betweenendocannabinoids and cholecystokinin

Kurrikoff K, Inno J, Matsui T, Vasar E

2008 44Infect Immun 2008 04 76 4 1728 37 Fcgamma receptor regulation of Citrobacter rodentium infection

Masuda A, Yoshida M, Shiomi H, Ikezawa S, Takagawa T, TanakaH, Chinzei R, Ishida T, Morita Y, Kutsumi H, Inokuchi H, Wang S,Kobayashi K, Mizuno S, Nakamura A, Takai T, Blumberg RS,

2008 45 Biomed Res 2008 04 29 2 93 8Circadian expression of 86- and 84-kDa heat shock proteins in themouse suprachiasmatic nucleus

Fukuyama T, Doi M, Matsuo M, Nishinaga H, Miyake S, OkamuraH

2008 46 J Orthop Sci 2008 03 13 2 130 5Fas ligand expression on human nucleus pulposus cells decreases withdisc degeneration processes

Kaneyama S, Nishida K, Takada T, Suzuki T, Shimomura T,Maeno K, Kurosaka M, Doita M

2008 47 Diabetes 2008 03 57 3 563 76Forkhead transcription factor FoxO1 in adipose tissue regulatesenergy storage and expenditure

Nakae J, Cao Y, Oki M, Orba Y, Sawa H, Kiyonari H, Iskandar K,Suga K, Lombes M, Hayashi Y

2008 48 J Androl 2008 03 29 2 153 163Oral administration of tetrahydrobiopterin attenuates testiculardamage by reducing nitric oxide synthase activity in a cryptorchid

Kondo Y, Ishikawa T, Yamaguchi K, Yada T, Fujisawa M

2008 49 Stem Cells 2008 03 26 3 819 30Administrations of peripheral blood CD34-positive cells contribute tomedial collateral ligament healing via vasculogenesis

Tei K, Matsumoto T, Mifune Y, Ishida K, Sasaki K, Shoji T, KuboS, Kawamoto A, Asahara T, Kurosaka M, Kuroda R

2008 50FEBS Lett 2008 03 582 5 573 8

Chemerin enhances insulin signaling and potentiates insulin-stimulatedglucose uptake in 3T3-L1 adipocytes

Takahashi M, Takahashi Y, Takahashi K, Zolotaryov FN, HongKS, Kitazawa R, Iida K, Okimura Y, Kaji H, Kitazawa S, Kasuga M,Chihara K

2008 51 Int J Oncol 2008 03 32 3 603 8Anti-tumor effect of pegylated interferon in the rathepatocarcinogenesis model

Miki A, Yano Y, Kato H, Seo Y, Kuriyama M, Azuma T, Hayashi Y

2008 52 Mol Cell Endocrinol 2008 02 283 1-2 68 75Cisplatin regulates Sertoli cell expression of transferrin andinterleukins

Yamaguchi K, Ishikawa T, Kondo Y, Fujisawa M

2008 53Nat Med 2008 02 14 2 188 93

Dok1 mediates high-fat diet-induced adipocyte hypertrophy andobesity through modulation of PPAR-gamma phosphorylation

Hosooka T, Noguchi T, Kotani K, Nakamura T, Sakaue H, InoueH, Ogawa W, Tobimatsu K, Takazawa K, Sakai M, Matsuki Y,Hiramatsu R, Yasuda T, Lazar MA, Yamanashi Y, Kasuga M

2008 54 Bone 2008 02 42 2 372 9Bone formation in spontaneously diabetic Torii-newly establishedmodel of non-obese type 2 diabetes rats

Fujii H, Hamada Y, Fukagawa M

2008 55 Kobe J Med Sci 2008 02 53 6 275 81 Generation of RGS8 null mutant mice by Cre/loxP system Kuwata H, Nakao K, Harada T, Matsuda I, Aiba A

2008 56Life Sci 2008 02 82 9-10 460 6

GHRP-2, a GHS-R agonist, directly acts on myocytes to attenuatethe dexamethasone-induced expressions of muscle-specific ubiquitinligases, Atrogin-1 and MuRF1

Yamamoto D, Ikeshita N, Matsubara T, Tasaki H, Herningtyas EH,Toda K, Iida K, Takahashi Y, Kaji H, Chihara K, Okimura Y

2008 57Am J Physiol Heart Circ Physiol 2008 02 294 2 H1094 100

Atherosclerotic plaque imaging using phase-contrast X-ray computedtomography

Shinohara M, Yamashita T, Tawa H, Takeda M, Sasaki N, TakayaT, Toh R, Takeuchi A, Ohigashi T, Shinohara K, Kawashima S,Yokoyama M, Hirata K, Momose A

2008 58 Kobe J Med Sci 2008 02 53 6 317 26Loss of CO2-induced distensibility in cerebral arteries with chronichypertension or vasospasm after subarachnoid hemorrhage

Nakajima S, Kondoh T, Morishita A, Yamashita H, Kohmura E,Sakurai T, Yokono K, Umetani K

2008 59 FEBS Lett 2008 01 582 1 54 67 The FoxO transcription factors and metabolic regulation Nakae J, Oki M, Cao Y

2008 60Urology 2008 01 71 1 156 60

Etodolac, a selective cyclooxygenase-2 inhibitor, induces upregulationof E-cadherin and has antitumor effect on human bladder cancer cellsin vitro and in vivo

Okamoto A, Shirakawa T, Bito T, Shigemura K, Hamada K, GotohA, Fujisawa M, Kawabata M

2008 61 Cancer Res 2008 01 68 1 64 72Crucial role of phospholipase C epsilon in skin inflammation inducedby tumor-promoting phorbol ester

Ikuta S, Edamatsu H, Li M, Hu L, Kataoka T

2008 62 Mol Cell Endocrinol 2008 01 280 1-2 20 9Involvement of mPOU (Brn-5), a class VI POU protein, in the geneexpression of Pit-1 as well as PRL

Toda K, Yamamoto D, Fumoto M, Ikeshita N, Herningtyas EH,Iida K, Takahashi Y, Kaji H, Chihara K, Okimura Y

2008 63 Kobe J Med Sci 2008 00 54 4 E217 E226Expression of beta-catenin and Integrin-linked kinase in the mousesciatic nerve

Takeuchi J, Shibuya Y, Murata M, Komori T

2008 64

Oral Surg Oral Med Oral PatholOral Radiol Endod

2008 00 105 なし 486 490

Lymph node and pulmonary metastases after transplantation of oralsquamous cell line (HSC-3) into the subcutaneous tissue of nudemouse:detection of metastases by genetic methods using β-globinand mutantp 53 genes

Shigeta T, Umeda M, Komatsubara H, Komori T

2008 65 Mod Rheumatol 2008 00 18 2 203 7A case of periodic-fever-syndrome-like disorder with lipodystrophy,myositis, and autoimmune abnormalities

Kasagi S, Kawano S, Nakazawa T, Sugino H, Koshiba M, IchinoseK, Ida H, Eguchi K, Kumagai S

2008 66J Gastroenterol 2008 00 43 5 390 6

Decreased expression of intestinal chemokine TECK/CCL25 inexperimental obstructive jaundice and its reversal following internalbiliary drainage

Matsumoto T, Ajiki T, Kajiwara E, Mita Y, Fujita T, Morimoto H,Miyazawa M, Ku Y

2008 67 J Neurosci 2008 00 28 4414 4422Semaphorin 3F confines ventral tangential migration of lateralolfactory tract neurons onto telencephalon surface

Ito K, Kawasaki T, Takashima S, Matsuda I, Aiba A, and Hirata T

2008 68 生体の科学 2008 12 596

号490 496 【mTORをめぐるシグナルタンパク】 TSC2ノックアウトマウス 小柳真希, 木戸良明, 春日雅人

2008 69 日本腰痛学会雑誌 2008 10 141

号50 57 【腰痛の基礎研究】 椎間板の免疫特権と腰痛との関係

西田康太郎, 金山修一, 高田徹, 前野耕一郎, 黒坂昌弘, 土井田稔

2008 70 The Lipid 2008 10 194

号402 408

【ω3多価不飽和脂肪酸　 近の進歩】 ω3多価不飽和脂肪酸と粘膜免疫応答・炎症性腸疾患

石田司, 吉田優, 東健, 西谷洋輔, 有田誠

2008 71 アンチ・エイジング医学 2008 10 45

号625 628 【感覚器のアンチエイジング】 嗅覚の加齢とアンチエイジング 丹生健一

2008 72 移植 2008 10 435

号351 356 【移植における臓器保存】 膵臓および膵島移植における保存法 辻村敏明, 黒田嘉和

2008 73実験医学 2008 9 26

15号

2368 2372【シグナル伝達研究　2008'09　疾患発症の分子メカニズムと実現化する分子標的薬開発】 シグナル伝達研究　因子から現象へ　受容体型チロシンキナーゼRor2によるWntシグナルの制御

西田満, 南康博

2008 74 医学のあゆみ 2008 9 22611号

991 995 【感覚器の再生医療】 嗅覚の再生医療　嗅上皮の再生に向けて 丹生健一, 土井清司, 西川匡, 越智尚樹

2008 75 日本整形外科学会雑誌 2008 8 828

号S1157 S1157 Fas ligandはラット由来骨髄間葉系細胞の骨分化を抑制する

酒井良忠, 三輪雅彦, 大江啓介, 新倉隆宏, 岩倉崇, 李相亮, 黒坂昌弘

2008 76 呼吸 2008 8 278

号776 782 スフィンゴシンキナーゼ/スフィンゴシン1リン酸シグナルと呼吸器疾患 西馬照明, 西村善博

2008 77 癌と化学療法 2008 7 357

号1126 1131 頭頸部癌　遺伝子診断・治療の現況 大月直樹, 丹生健一

2008 78 頭頸部自律神経 2008 6 22 18 20ヒト線維芽細胞増殖因子(bFGF)点鼻によるマウス嗅上皮の変化に対する免疫組織学的検討

西川匡, 丹生健一

2008 79 臨床免疫・アレルギー科 2008 5 495

号599 605 腸内細菌防御とFcγレセプター

塩見英之, 吉田優, 増田充弘, 高川哲也, 小畑大輔, 森田圭紀,久津見弘, 水野成人, 井口秀人, 東健

2008 80

日本臨床 2008 5 66

増刊3

新時代の糖尿病学

632 637

【新時代の糖尿病学　病因・診断・治療研究の進歩】 糖尿病基礎研究の進歩　糖尿病モデル動物　実験的糖尿病モデル動物　発生工学手法による糖尿病モデル動物　ノックアウトマウス　1型糖尿病モデル・ノックアウトマウス

森山啓明, 永田正男, 横野浩一

2008 81 糖尿病 2008 5 515

号395 397

【臓器間クロストークによるエネルギー代謝調節】 単球・マクロファージとエネルギー代謝調節

田守義和

2008 82 Diabetes Frontier 2008 4 192

号185 190 【1型糖尿病の新展開】 1型糖尿病の成因　自己免疫(細胞性) 安田尚史, 永田正男

2008 83日本マイクロサージャリー学会会誌

2008 3 211

号28 32 順行性トレーサー法による舌下神経染色法

榊原俊介, 橋川和信, 石田泰久, 永田育子, 大守誠, 寺師浩人,田原真也

2008 84 日本口腔インプラント学会誌 2008 3 211

号199 199

β-リン酸三カルシウム(β-TCP)内への骨髄幹細胞(BMSC)導入方法と骨形成能の検討

長谷川巧実, 澁谷恭之, 三輪雅彦, 酒井良忠, 新倉隆宏, 大江啓介, 岩倉崇, 黒坂昌弘, 古森孝英

2008 85 日本耳鼻咽喉科学会会報 2008 2 1112

号45

46,np1-np2

嗅覚研究・臨床の進歩　嗅神経細胞の再生医療 丹生健一, 土井清司, 越智尚樹, 西川匡

2008 86 Diabetes Frontier 2008 2 191

号27 31 【インスリン抵抗性と炎症】 脂肪組織と炎症　脂肪細胞肥大化と炎症 田守義和, 春日雅人

2008 87Annual Review糖尿病・代謝・内分泌

2008 1 2008 1 9 糖尿病　基礎分野での進歩 炎症とインスリン抵抗性 田守義和, 春日雅人

2008 88 関西実験動物研究会会報 2008 0 30 1 12トランスレーショナルリサーチにおけるWHHL/WHHLMIウサギの役割－高脂血症、動脈硬化等について－．

塩見 雅志

2007 1 Arch Histol Cytol 2007 12 70 5 297 301Anterograde labeling of the corticospinal tract in jimpy mutant miceby Di I injection into the motor cortex

Shibata-Iwasaki R, Dekimoto H, Katsuyama Y, Kikkawa S,Terashima T

2007 2 Dev Biol 2007 12 312 2 509 22Tight junctions containing claudin 4 and 6 are essential for blastocystformation in preimplantation mouse embryos

Moriwaki K, Tsukita S, Furuse M

2007 3 J Heart Lung Transplant 2007 12 26 12 1320 5Ischemically damaged heart after preservation by the cavitary two-layer method as a possible donor in rat heart transplantation

Kamoda Y, Fujino Y, Tanioka Y, Sakai T, Kuroda Y

2007 4 J Invest Dermatol 2007 12 127 12 2865 71Narrow-band UVB induces more carcinogenic skin tumors thanbroad-band UVB through the formation of cyclobutane pyrimidine

Kunisada M, Kumimoto H, Ishizaki K, Sakumi K, Nakabeppu Y,Nishigori C

2007 5 Invest Ophthalmol Vis Sci 2007 12 48 12 5716 21Antiangiogenic effects of bisphosphonates on laser-induced choroidalneovascularization in mice

Nagai T, Imai H, Honda S, Negi A

2007 6 Proc Natl Acad Sci U S A 2007 12 104 49 19333 19338Essential role of Epac2/Rap1 signaling in regulation of insulin granuledynamics by cAMP

Shibasaki T, Takahashi H, Miki T, Sunaga Y, Matsumura K,Yamanaka M, Zhang C, Tamamoto A, Satoh T, Miyazaki J, Seino

2007 7 Biochem Biophys Res Commun 2007 12 364 4 1037 42CXCL14 enhances insulin-dependent glucose uptake in adipocytesand is related to high-fat diet-induced obesity

Takahashi M, Takahashi Y, Takahashi K, Zolotaryov FN, HongKS, Iida K, Okimura Y, Kaji H, Chihara K

2007 8 Biochem Biophys Res Commun 2007 11 363 1 106 112Defective vascular morphogenesis and mid-gestation embryonic deathin mice lacking RA-GEF-1

Wei P, Satoh T, Edamatsu H, Aiba A, Setsu T, Terashima T,Kitazawa S, Nakao K, Yoshikawa Y, Tamada M, Kataoka T

2007 9 J Neurooncol 2007 11 85 2 123 32Trans-4-lodo,4'-boranyl-chalcone induces antitumor activity againstmalignant glioma cell lines in vitro and in vivo

Sasayama T, Tanaka K, Mizukawa K, Kawamura A, Kondoh T,Hosoda K, Kohmura E

2007 10 Arterioscler Thromb Vasc Biol 2007 11 27 11 2384 91Local overexpression of toll-like receptors at the vessel wall inducesatherosclerotic lesion formation: synergism of TLR2 and TLR4

Shinohara M, Hirata K, Yamashita T, Takaya T, Sasaki N, ShirakiR, Ueyama T, Emoto N, Inoue N, Yokoyama M, Kawashima S

2007 11 Am J Respir Cell Mol Biol 2007 10 37 4 395 404Sphingosine kinase 1 regulates differentiation of human and mouselung fibroblasts mediated by TGF-beta1

Kono Y, Nishiuma T, Nishimura Y, Kotani Y, Okada T, NakamuraS, Yokoyama M

2007 12Br J Haematol 2007 10 139 1 161 3

Deregulation of a possible tumour suppressor gene, ZC3H12D, bytranslocation of IGK@ in transformed follicular lymphoma witht(2;6)(p12;q25)

Minagawa K, Yamamoto K, Nishikawa S, Ito M, Sada A, YakushijinK, Okamura A, Shimoyama M, Katayama Y, Matsui T

2007 13Biomed Microdevices 2007 10 9 5 719 727

Localization to atherosclerotic plaque and biodistribution ofbiochemically derivatized superparamagnetic iron oxide nanoparticles(SPIONs) contrast particles for magnetic resonance imaging (MRI)

Smith BR, Heverhagen J, Knopp M, Schmalbrock P, Shapiro J,Shiomi M, Moldovan NI, Ferrari M, Lee SC

2007 14 J Urol 2007 10 178 4 Pt 1 1504 9Interleukin-21 activates cytotoxic T lymphocytes and natural killercells to generate antitumor response in mouse renal cell carcinoma

Kumano M, Hara I, Furukawa J, Oniki S, Nagai H, Miyake H,Fujisawa M

2007 15 Eur J Neurosci 2007 10 26 8 2142 50Different effects of monocarboxylates on neuronal survival and beta-amyloid toxicity

Wang X, Takata T, Sakurai T, Yokono K

2007 16 Cell Commun Adhes 2007 10 14 4 157 67Double-layered collagen gel hemisphere for cell invasion assay:successful visualization and quantification of cell invasion activity

Takata M, Maniwa Y, Doi T, Tanaka Y, Okada K, Nishio W,Ohbayashi C, Yoshimura M, Hayashi Y, Okita Y

2007 17 Curr Eye Res 2007 10 32 10 903 10The upregulation of angiogenic gene expression in cultured retinalpigment epithelial cells grown on type I collagen

Imai H, Honda S, Kondo N, Ishibashi K, Tsukahara Y, Negi A

2007 18 Eur J Pharmacol 2007 09 571 1 62 71Neutrophil elastase inhibitor (sivelestat) attenuates subsequentventilator-induced lung injury in mice

Sakashita A, Nishimura Y, Nishiuma T, Takenaka K, Kobayashi K,Kotani Y, Yokoyama M

2007 19 J Biol Chem 2007 09 282 37 27493 502Protein kinase D-mediated phosphorylation and nuclear export ofsphingosine kinase 2

Ding G, Sonoda H, Yu H, Kajimoto T, Goparaju SK, Jahangeer S,Okada T, Nakamura S

2007 20 Diabetes Res Clin Pract 2007 09 77 Suppl 1 S99 103 Immunological aspects of 'fulminant type 1 diabetes'Nagata M, Moriyama H, Kotani R, Yasuda H, Kishi M, Kurohara M,Hara K, Yokono K

2007 21 Diabetes Res Clin Pract 2007 09 77 Suppl 1 S155 60Insulin as a T cell antigen in type 1 diabetes supported by theevidence from the insulin knockout NOD mice

Moriyama H, Nagata M, Arai T, Okumachi Y, Yamada K, Kotani R,Yasuda H, Hara K, Yokono K

2007 22J Neurooncol 2007 09 84 3 233 44

Specific mTOR inhibitor rapamycin enhances cytotoxicity induced byalkylating agent 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea (ACNU) in human U251 malignant glioma

Tanaka K, Sasayama T, Mizukawa K, Kawamura A, Kondoh T,Hosoda K, Fujiwara T, Kohmura E

2007 23 J Atheroscler Thromb 2007 08 14 4 192 201Endothelial lipase is increased by inflammation and promotes LDLuptake in macrophages

Yasuda T, Hirata K, Ishida T, Kojima Y, Tanaka H, Okada T,Quertermous T, Yokoyama M

2007 24 Development 2007 08 134 15 2719 25Unique mechanisms of growth regulation and tumor suppression uponApc inactivation in the pancreas

Strom A, Bonal C, Ashery-Padan R, Hashimoto N, Campos ML,Trumpp A, Noda T, Kido Y, Real FX, Thorel F, Herrera PL

2007 25 Mol Biol Cell 2007 08 18 8 2949 2959The M-Ras-RA-GEF-2-Rap1 pathway mediates tumor necrosisfactor-{alpha}-dependent regulation of integrin activation in

Yoshikawa Y, Satoh T, Tamura T, Wei P, Bilasy SE, Edamatsu H,Aiba A, Katagiri K, Kinashi T, Nakao K, Kataoka T

2007 26 Ann Thorac Surg 2007 08 84 2 488 92Influence of perioperative hemodynamics on spinal cord ischemia inthoracoabdominal aortic repair

Kawanishi Y, Okada K, Matsumori M, Tanaka H, Yamashita T,Nakagiri K, Okita Y

2007 27Cancer Immunol Immunother 2007 07 56 7 1025 36

Superior anti-tumor protection and therapeutic efficacy ofvaccination with allogeneic and semiallogeneic dendritic cell/tumorcell fusion hybrids for murine colon adenocarcinoma

Yasuda T, Kamigaki T, Kawasaki K, Nakamura T, Yamamoto M,Kanemitsu K, Takase S, Kuroda D, Kim Y, Ajiki T, Kuroda Y

2007 28 Am J Sports Med 2007 07 35 7 1098 104In Vivo Measurement of the Pivot-Shift Test in the Anterior CruciateLigament-Deficient Knee Using an Electromagnetic Device

Hoshino Y, Kuroda R, Nagamune K, Yagi M, Mizuno K, YamaguchiM, Muratsu H, Yoshiya S, Kurosaka M

2007 29 Am J Physiol Cell Physiol 2007 06 293 3 C865 73Xenogenic macrophage immunization reduces atherosclerosis inapolipoprotein E knockout mice

Yamashita T, Kawashima S, Hirase T, Shinohara M, Takaya T,Sasaki N, Takeda M, Tawa H, Inoue N, Hirata KI, Yokoyama M

2007 30 Neuron 2007 06 54 5 813 29 microRNA Modulation of Circadian-Clock Period and EntrainmentCheng HY, Papp JW, Varlamova O, Dziema H, Russell B,Curfman JP, Nakazawa T, Shimizu K, Okamura H, Impey S,

2007 31 J Cell Sci 2007 06 120 12 2078 2090Regulated Nodal signaling promotes differentiation of the definitiveendoderm and mesoderm from ES cells

Takenaga M, Fukumoto M, Hori Y

2007 32Nephrol Dial Transplant 2007 06 22 6 1547 57

Overexpression of thioredoxin1 in transgenic mice suppressesdevelopment of diabetic nephropathy

Hamada Y, Miyata S, Nii-Kono T, Kitazawa R, Kitazawa S, HigoS, Fukunaga M, Ueyama S, Nakamura H, Yodoi J, Fukagawa M,Kasuga M

2007 33 J Thorac Cardiovasc Surg 2007 06 133 6 1553 8The adverse effect of back-bleeding from lumbar arteries on spinalcord pathophysiology in a rabbit model

Kawanishi Y, Okada K, Tanaka H, Yamashita T, Nakagiri K, OkitaY

2007 34Hum Gene Ther 2007 05 18 5 389 400

Modification of the Rb-binding domain of replication-competentadenoviral vector enhances cytotoxicity against human esophagealcancers via NF-kappaB activity

Yamada K, Moriyama H, Yasuda H, Hara K, Maniwa Y, Hamada H,Yokono K, Nagata M

2007 35Pancreas 2007 05 34 4 410 6

Protective effects of vascular endothelial growth factor on intestinalepithelial apoptosis and bacterial translocation in experimental severeacute pancreatitis

Nakajima T, Ueda T, Takeyama Y, Yasuda T, Shinzeki M, Sawa H,Kuroda Y

2007 36 Bone 2007 05 40 5 1408 14Histomorphometric analysis of diabetic osteopenia in streptozotocin-induced diabetic mice: a possible role of oxidative stress

Hamada Y, Kitazawa S, Kitazawa R, Fujii H, Kasuga M, FukagawaM

2007 37 Tissue Eng 2007 05 13 5 1103 12The regenerative effects of platelet-rich plasma on meniscal cells invitro and its in vivo application with biodegradable gelatin hydrogel

Ishida K, Kuroda R, Miwa M, Tabata Y, Hokugo A, Kawamoto T,Sasaki K, Doita M, Kurosaka M

2007 38 J Thorac Cardiovasc Surg 2007 05 133 5 1268 1276Autologous fibrin-coated small-caliber vascular prostheses improveantithrombogenicity by reducing immunologic response

Hasegawa T, Okada K, Takano Y, Hiraishi Y, Okita Y

2007 39 Mol Cell Biol 2007 05 27 9 3429 40Involvement of sphingosine-1-phosphate in glutamate secretion inhippocampal neurons

Kajimoto T, Okada T, Yu H, Goparaju SK, Jahangeer S,Nakamura S

2007 40Diabetes 2007 04 56 4 1000 9

Restoration of glucokinase expression in the liver normalizespostprandial glucose disposal in mice with hepatic deficiency of PDK1

Okamoto Y, Ogawa W, Nishizawa A, Inoue H, Teshigawara K,Kinoshita S, Matsuki Y, Watanabe E, Hiramatsu R, Sakaue H,Noda T, Kasuga M

2007 41Lin Chung Er Bi Yan Hou TouJing Wai Ke Za Zhi

2007 04 21 8 363 5[The expression of neuN in the development of olfactory bulb andepithelium of mice]

Wei H, Li X, Yu G, Cao Z, Nibu K

2007 42Arterioscler Thromb Vasc Biol 2007 04 27 7 1632 7

A Specific Role for eNOS-Derived Reactive Oxygen Species inAtherosclerosis Progression

Takaya T, Hirata KI, Yamashita T, Shinohara M, Sasaki N, InoueN, Yada T, Goto M, Fukatsu A, Hayashi T, Alp NJ, Channon KM,Yokoyama M, Kawashima S

2007 43 J Surg Res 2007 04 138 2 300 7Protective effect of caspase inhibitor on intestinal integrity inexperimental severe acute pancreatitis

Yasuda T, Takeyama Y, Ueda T, Shinzeki M, Kishi S, Sawa H,Nakajima T, Kuroda Y

2007 44 Neurosci Res 2007 04 57 4 538 43Metabotropic glutamate receptor subtype-1 is essential for motorcoordination in the adult cerebellum

Nakao H, Nakao K, Kano M, Aiba A

2007 45 Ann Surg Oncol 2007 04 14 4 1374 80Antitumor effect of gemcitabine on orthotopically inoculated humangallbladder cancer cells in nude mice

Mita Y, Ajiki T, Kamigaki T, Okazaki T, Hori H, Horiuchi H, HirataK, Fujita T, Fujimori T, Kuroda Y

2007 46 Brain Res 2007 04 1140 1 205 15The superficial layers of the superior colliculus are cytoarchitectuallyand myeloarchitectually disorganized in the reelin-deficient mouse,

Baba K, Sakakibara S, Setsu T, Terashima T

2007 47 J Neurosci 2007 04 27 16 4359 65 Vagal regulation of respiratory clocks in miceBando H, Nishio T, van der Horst GT, Masubuchi S, Hisa Y,Okamura H

2007 48 Arterioscler Thromb Vasc Biol 2007 03 27 3 548 55Controlled release of basic fibroblast growth factor from gelatinhydrogel sheet improves structural and physiological properties of

Haraguchi T, Okada K, Tabata Y, Maniwa Y, Hayashi Y, Okita Y

2007 49J Cell Physiol 2007 03 210 3 561 6

In vitro multipotentiality and characterization of human unfracturedtraumatic hemarthrosis-derived progenitor cells: A potential cellsource for tissue repair

Lee SY, Miwa M, Sakai Y, Kuroda R, Matsumoto T, Iwakura T,Fujioka H, Doita M, Kurosaka M

2007 50 Transplantation 2007 03 83 6 754 8Application of the two-layer method on pancreas digestion results inimproved islet yield and maintained viability of isolated islets

Goto T, Tanioka Y, Sakai T, Terai S, Kamoda Y, Li S, Tanaka T,Tsujimura T, Matsumoto I, Fujino Y, Suzuki Y, Kuroda Y

2007 51 Biochem Biophys Res Commun 2007 03 354 4 924 8 Circadian expression of clock genes in human peripheral leukocytesFukuya H, Emoto N, Nonaka H, Yagita K, Okamura H, YokoyamaM

2007 52Gastroenterology 2007 03 132 3 938 43

Growth hormone reverses nonalcoholic steatohepatitis in a patientwith adult growth hormone deficiency

Takahashi Y, Iida K, Takahashi K, Yoshioka S, Fukuoka H, TakenoR, Imanaka M, Nishizawa H, Takahashi M, Seo Y, Hayashi Y,Kondo T, Okimura Y, Kaji H, Kitazawa R, Kitazawa S, Chihara K

2007 53Arch Otolaryngol Head NeckSurg

2007 03 133 3 270 5Induction of immunological antitumor effects by adenovirus-mediatedgene transfer of B7-1 in a murine squamous cell carcinoma cell line

Hoshitani Y, Ishida H, Otsuki N, Shirakawa T, Gotoh A, Nibu K

2007 54 Regul Pept 2007 02 138 2-3 141 4Neither intravenous nor intracerebroventricular administration ofobestatin affects the secretion of GH, PRL, TSH and ACTH in rats

Yamamoto D, Ikeshita N, Daito R, Herningtyas EH, Toda K,Takahashi K, Iida K, Takahashi Y, Kaji H, Chihara K, Okimura Y

2007 55 Diabetes 2007 02 56 2 506 12Genetic reconstitution of autoimmune type 1 diabetes with two majorsusceptibility genes in the rat

Yokoi N, Hayashi C, Fujiwara Y, Wang HY, Seino S

2007 56 Biochem Biophys Res Commun 2007 02 353 3 623 7Obesity-induced upregulation of myocardial endothelin-1 expressionis mediated by leptin

Adiarto S, Emoto N, Iwasa N, Yokoyama M

2007 57 J Bone Joint Surg Br 2007 02 89 2 258 64Repair of osteochondral defects with a new porous synthetic polymerscaffold

Nagura I, Fujioka H, Kokubu T, Makino T, Sumi Y, Kurosaka M

2007 58 J Bone Joint Surg Br 2007 01 89 1 133 8An in vitro study demonstrating that haematomas found at the site ofhuman fractures contain progenitor cells with multilineage capacity

Oe K, Miwa M, Sakai Y, Lee SY, Kuroda R, Kurosaka M

2007 59 Anticancer Res 2007 01 27 1A 423 9Imatinib mesylate inhibits tumorigenicity of malignant fibroushistiocytoma cells in vivo

Irsan I, Akisue T, Hara H, Fujimoto T, Imabori M, Doita M, KurodaR, Fujioka H, Kawamoto T, Yamamoto T, Kurosaka M

2007 60 J Biol Chem 2007 01 282 3 2038 46Skp2 controls adipocyte proliferation during the development ofobesity

Sakai T, Sakaue H, Nakamura T, Okada M, Matsuki Y, WatanabeE, Hiramatsu R, Nakayama K, Nakayama KI, Kasuga M

2007 61 Surgery 2007 01 141 1 51 8Simple scoring system for the prediction of the prognosis of severeacute pancreatitis

Ueda T, Takeyama Y, Yasuda T, Matsumura N, Sawa H, NakajimaT, Ajiki T, Fujino Y, Suzuki Y, Kuroda Y

2007 62

Mol Endocrinol 2007 01 21 1 148 58

Methylation status of a single CpG locus 3 bases upstream of TATA-box of receptor activator of nuclear factor-kappaB ligand (RANKL)gene promoter modulates cell- and tissue-specific RANKL expressionand osteoclastogenesis

Kitazawa R, Kitazawa S

2007 63 Kobe J Med Sci 2007 00 53 1-2 53 61A possible role of thioredoxin interacting protein in the pathogenesisof streptozotocin-induced diabetic nephropathy

Hamada Y, Fukagawa M

2007 64 Methods Mol Biol 2007 00 362 1 481 92Suprachiasmatic nucleus cultures that maintain rhythmic properties invitro

Tominaga-Yoshino K, Ueyama T, Okamura H

2007 65Microbiol Immunol 2007 00 51 1 15 24

Survey of Babesia microti infection in field rodents in Japan: Recordsof the Kobe-type in new foci and findings of a new type related to theOtsu-type

Saito-Ito A, Kasahara M, Kasai M, Dantrakool A, Kawai A, FujitaH, Yano Y, Kawabata H, Takada N

2007 66 Kobe J Med Sci 2007 00 53 3 125 34Adenoviral transfer of rho family proteins to lung cancer cellsameliorates cell proliferation and motility and increases apoptotic

Shimada T, Nishimura Y, Nishiuma T, Rikitake Y, Hirase T,Yokoyama M

2007 67 Cell Transplant 2007 00 16 5 539 45Improved quantity and in vivo function of islets isolated by reducedpressure-controlled injection of collagenase in a rat model

Li S, Sakai T, Suzuki Y, Goto T, Tanaka T, Yoshikawa T, KakinokiK, Tanioka Y, Matsumoto I, Fujino Y, Kuroda Y

2007 68Intern Med 2007 00 46 18 1577 83

McCune-Albright syndrome with acromegaly and fibrous dysplasiaassociated with the GNAS gene mutation identified by sensitive PNA-clamping method

Imanaka M, Iida K, Nishizawa H, Fukuoka H, Takeno R, TakahashiK, Kaji H, Takahashi Y, Okimura Y, Kaji H, Imanishi Y, Chihara K

2007 69 Kobe J Med Sci 2007 00 53 5 199 207Effect of VEGF Receptor Antagonist (VGA1155) on Brain Edema inthe Rat Cold Injury Model

Koyama J, Miyake S, Sasayama T, Kondoh T, Kohmura E

2007 70 Kobe J Med Sci 2007 00 53 5 257 263Alveolar ridge augmentation using various bone substitutes -a webform of titanium fibers promotes rapid bone development-

Masago H, Shibuya Y, Munemoto S, Takeuchi J, Umeda M,Kuboki Y, Komori T

2007 71 Kobe J Med Sci 2007 00 53 5 219 27Decreased Expression of Toll-like Receptor 2 and 4 on Macrophagesin Experimental Severe Acute Pancreatitis

Matsumura N, Takeyama Y, Ueda T, Yasuda T, Shinzeki M, SawaH, Nakajima T, Kuroda Y

2007 72Conf Proc IEEE Eng Med BiolSoc

2007 00 29 3926 3929In Vivo Cerebral Artery Microangiography in Rat and Mouse UsingSynchrotron Radiation Imaging System

Umetani K, Kidoguchi K, Morishita A, Oizumi XS, Tamaki M,Yamashita H, Sakurai T, Kondoh T

2007 73 Surg Today 2007 00 37 10 867 73Role of toll-like receptor 4 in the pathophysiology of severe acutepancreatitis in mice

Sawa H, Ueda T, Takeyama Y, Yasuda T, Shinzeki M, Nakajima T,Kuroda Y

2007 74 Dev Neurosci 2007 00 29 1-2 59 72Postnatal development of entorhinodentate projection of the Reelermutant mouse

Muraoka D, Katsuyama Y, Kikkawa S, Terashima T

2007 75 IBD Research 2007 9 13

号184 188

【分子メカニズムから探るIBDの病態と治療アプローチ】 腸管免疫監視機構におけるIgGの役割とIBD

塩見英之, 吉田優, 増田充弘, 森田圭紀, 久津見弘, 井口秀人,東健

2007 76 日本生殖内分泌学会雑誌 2007 9 12 21 25セルトリ細胞においてIL-1βはJNK経路を活性化し、一酸化窒素(NO)発現を亢進させる

石川智基, Morris Patricia L., 藤澤正人

2007 77 神緑会学術誌 2007 8 23 84 85 胃炎、胃癌における免疫細胞の役割 吉田優

2007 78 肥満研究 2007 8 132

号124 129 メタボリックシンドロームとインスリン抵抗性 春日雅人, 田守義和, 阪上浩

2007 79 G.I.Research 2007 8 154

号340 341

n-3系不飽和脂肪酸生理活性物質を用いたクローン病新規治療法の開発

石田司, 吉田優, 有田誠, 東健

2007 80 日本整形外科学会雑誌 2007 8 818

号S1146 S1146

超音波を利用した骨髄細胞/人工骨複合体内導入細胞数の非破壊的定量法の開発

大江啓介, 三輪雅彦, 酒井良忠, 新倉隆宏, 柴沼均, 黒坂昌弘

2007 81 日本整形外科学会雑誌 2007 8 818

号S840 S840 自家骨軟骨移植におけるFGF-2含有ゼラチンハイドロゲルの効果 中山潤一, 藤岡宏幸, 名倉一成, 黒田良祐, 田畑泰彦, 黒坂昌弘

2007 82 日本整形外科学会雑誌 2007 8 818

号S839 S839 生体吸収性高分子Scaffold単独移植による軟骨修復 名倉一成, 藤岡宏幸, 豊川成和, 国分毅, 兼子博章, 黒坂昌弘

2007 83 日本整形外科学会雑誌 2007 7 817

号537 544

椎間板再生の現状と展望　RNA干渉を介した椎間板内の特異的遺伝子に対する発現抑制　超音波コントラスト法による椎間板への遺伝子

西田康太郎, 角谷賢一朗, 土井田稔, 下村隆敏, 前野耕一郎, 金山修一, 鈴木哲平, 黒坂昌弘

2007 84MEDICAL IMAGINGTECHNOLOGY

2007 7 25Su

ppl.C3 3 ラット・マウスでの放射光による脳血管反応性の観察 梅谷啓二, 近藤威, 櫻井孝, 山下晴央, 木戸口慶司, 森下暁二

2007 85 分子消化器病 2007 6 42

号155 158

シグナル伝達を理解するために必要な知識　Fcレセプターを介したシグナル伝達

増田充弘, 吉田優, 石田司, 井口秀人, 東健

2007 86 日本医師会雑誌 2007 6 136特別

S308 S310【メタボリックシンドロームup to date】 トピックス　メタボリックシンドロームの分子基盤と炎症・細胞機能

田守義和, 春日雅人

2007 87 実験医学 2007 5 258

号1254 1260

基礎研究の新たな方向性を解く　疾患解明Overview　Helicobacterpylori感染と胃癌

東健, 田中擴址, 森田圭紀, 吉田優, 久津見弘

2007 88 日本小児科学会雑誌 2007 2 1112

号272 272 時計遺伝子はどのようにしてリズムを刻むのか 岡村均

2007 89 脊椎脊髄ジャーナル 2007 1 201

号12 20

【椎間板のbiology】 変性椎間板に対するアプローチ　遺伝子治療の観点から

西田康太郎, 土井田稔, 角谷賢一朗, 下村隆敏, 前野耕一郎, 黒坂昌弘

2007 90 実験動物技術 2007 0 42 1 1 8 骨成長異常によるWHHLMIウサギの斜頸． 田村 敏昌，伊藤 隆，山根 香織，山田 悟士，塩見 雅志

2007 91 実験動物技術 2007 0 42 1 15 22 実験用ウサギの死後の観察と組織変化 田村敏昌，伊藤隆，山田悟士，塩見雅志

2007 92 糖尿病学2007 2007 0 55 62 インスリンシグナルと膵β細胞量 木戸良明、竹田章彦、中野尚子、春日雅人

2006 1 World J Gastroenterol 2006 12 12 47 7666 70Blockade of high mobility group box-1 protein attenuates experimentalsevere acute pancreatitis

Sawa H, Ueda T, Takeyama Y, Yasuda T, Shinzeki M, Nakajima T,Kuroda Y

2006 2Biochem Biophys Res Commun 2006 12 350 4 935 41

Molecular interaction between fukutin and POMGnT1 in theglycosylation pathway of alpha-dystroglycan

Xiong H, Kobayashi K, Tachikawa M, Manya H, Takeda S,Chiyonobu T, Fujikake N, Wang F, Nishimoto A, Morris GE, NagaiY, Kanagawa M, Endo T, Toda T

2006 3 Transplant Proc 2006 12 38 10 3289 92Intraperitoneal injection of oxygenated perfluorochemical improves theoutcome of intraportal islet transplantation in a rat model

Sakai T, Li S, Tanioka Y, Goto T, Tanaka T, Matsumoto I,Tsujimura T, Fujino Y, Suzuki Y, Kuroda Y

2006 4 Eur J Immunol 2006 12 36 12 3216 26Src homology 2 domain-containing protein tyrosine phosphatasesubstrate 1 regulates the induction of Langerhans cell maturation

Fukunaga A, Nagai H, Yu X, Oniki S, Okazawa H, Motegi S,Suzuki R, Honma N, Matozaki T, Nishigori C, Horikawa T

2006 5

Oncol Rep 2006 12 16 6 1317 24

Dendritic cell-tumor cell hybrids enhance the induction of cytotoxic Tlymphocytes against murine colon cancer: a comparative analysis ofantigen loading methods for the vaccination of immunotherapeuticdendritic cells

Yasuda T, Kamigaki T, Nakamura T, Imanishi T, Hayashi S,Kawasaki K, Takase S, Ajiki T, Kuroda Y

2006 6 Biochem Biophys Res Commun 2006 12 350 4 842 9A mouse homologue of Strawberry Notch is transcriptionally regulatedby Reelin signal

Baba K, Dekimoto H, Muraoka D, Agata K, Terashima T,Katsuyama Y

2006 7 J Cell Biol 2006 11 175 4 555 62Filopodia formation mediated by receptor tyrosine kinase Ror2 isrequired for Wnt5a-induced cell migration

Nishita M, Yoo SK, Nomachi A, Kani S, Sougawa N, Ohta Y,Takada S, Kikuchi A, Minami Y

2006 8 J Gene Med 2006 11 8 11 1341 6Genetically engineered Bifidobacterium animalis expressing theSalmonella flagellin gene for the mucosal immunization in a mouse

Takata T, Shirakawa T, Kawasaki Y, Kinoshita S, Gotoh A, KanoY, Kawabata M

2006 9Exp Eye Res 2006 11 83 5 1108 17

Latanoprost rescues retinal neuro-glial cells from apoptosis byinhibiting caspase-3, which is mediated by p44/p42 mitogen-activatedprotein kinase

Nakanishi Y, Nakamura M, Mukuno H, Kanamori A, Seigel GM,Negi A

2006 10 Pediatr Surg Int 2006 11 22 11 881 5Transplantation of the cryopreserved tracheal allograft in growingrabbits: effect of immunosuppressant

Hisamatsu C, Maeda K, Tanaka H, Okita Y

2006 11 Anticancer Res 2006 11 26 6B 4307 11Expression of VEGF and its receptors and angiogenesis in bone andsoft tissue tumors

Hara H, Akisue T, Fujimoto T, Imabori M, Kawamoto T, Kuroda R,Fujioka H, Yamamoto T, Doita M, Kurosaka M

2006 12J Nucl Med 2006 11 47 11 1845 1850

Application of 18F-FDG PET for Monitoring the Therapeutic Effect ofAntiinflammatory Drugs on Stabilization of Vulnerable AtheroscleroticPlaques

Ogawa M, Magata Y, Kato T, Hatano K, Ishino S, Mukai T, ShiomiM, Ito K, Saji H

2006 13 Behav Brain Res 2006 11 175 1 149 56 Gender specific effects of ethanol in mice, lacking CCK2 receptors Abramov U, Raud S, Innos J, Koks S, Matsui T, Vasar E

2006 14Neurosci Lett 2006 10 406 1-2 17 22

Differences in behavioural effects of amphetamine and dopamine-related gene expression in wild-type and homozygous CCK2 receptordeficient mice

Runkorg K, Varv S, Matsui T, Koks S, Vasar E

2006 15 J Vasc Surg 2006 10 44 4 840 5New assessment of platelet deposition in small caliber vascularprostheses using technetium-99m apcitide scintigraphy in rabbit

Hasegawa T, Okada K, Okita Y

2006 16 Neuroreport 2006 10 17 14 1549 53 Quantification of distension in rat cerebral perforating arteriesMorishita A, Kondoh T, Sakurai T, Ikeda M, Bhattacharjee AK,Nakajima S, Kohmura E, Yokono K, Umetani K

2006 17 Respirology 2006 09 11 5 546 56Overexpression of nitric oxide synthase by the endotheliumattenuates bleomycin-induced lung fibrosis and impairs MMP-

Yoshimura S, Nishimura Y, Nishiuma T, Yamashita T, KobayashiK, Yokoyama M

2006 18 Invest Ophthalmol Vis Sci 2006 09 47 9 4050 2 Circadian intraocular pressure rhythm is generated by clock genesMaeda A, Tsujiya S, Higashide T, Toida K, Todo T, Ueyama T,Okamura H, Sugiyama K

2006 19 J Urol 2006 09 176 3 1198 1203Interleukin-21 gene transfection into mouse bladder cancer cellsresults in tumor rejection through the cytotoxic T lymphocyte

Furukawa J, Hara I, Nagai H, Yao A, Oniki S, Fujisawa M

2006 20 J Clin Invest 2006 09 116 9 2473 2483The LXXLL motif of murine forkhead transcription factor FoxO1mediates Sirt1-dependent transcriptional activity

Nakae J, Cao Y, Daitoku H, Fukamizu A, Ogawa W, Yano Y,Hayashi Y

2006 21 J Surg Res 2006 09 135 1 18 26Breakdown of intestinal mucosa via accelerated apoptosis increasesintestinal permeability in experimental severe acute pancreatitis

Yasuda T, Takeyama Y, Ueda T, Shinzeki M, Sawa H, Nakajima T,Kuroda Y

2006 22 J Surg Res 2006 08 134 2 223 30Vascular endothelial growth factor increases in serum and protectsagainst the organ injuries in severe acute pancreatitis

Ueda T, Takeyama Y, Yasuda T, Matsumura N, Sawa H, NakajimaT, Kuroda Y

2006 23 Atherosclerosis 2006 08 187 2 257 264Chylomicron remnants upregulate CD40 expression via the ERKpathway and a redox-sensitive mechanism in THP-1 cells

Kamemura K, Fujioka Y, Takaishi H, Takahashi A, Taniguchi T,Ishikawa Y, Yokoyama M

2006 24 Arch Dermatol Res 2006 08 298 3 131 4Induction of cellular immunity against hair follicle melanocyte causesalopecia

Nagai H, Oniki S, Oka M, Horikawa T, Nishigori C

2006 25 J Cell Biochem 2006 08 98 6 1629 1644Modulation of mouse RANKL gene expression by Runx2 and PKApathway

Mori K, Kitazawa R, Kondo T, Maeda S, Yamaguchi A, Kitazawa S

2006 26 Stroke 2006 07 37 7 1856 1861In vivo X-ray angiography in the mouse brain using synchrotronradiation

Kidoguchi K, Tamaki M, Mizobe T, Koyama J, Kondoh T, KohmuraE, Sakurai T, Yokono K, Umetani K

2006 27 Int Immunopharmacol 2006 07 6 7 1040 1052The effect of overexpression of endothelial nitric oxide synthase oneosinophilic lung inflammation in a murine model

Kobayashi K, Nishimura Y, Yamashita T, Nishiuma T, Satouchi M,Yokoyama M

2006 28 Diabetes 2006 07 55 7 1930 1938Spontaneous recovery from hyperglycemia by regeneration ofpancreatic beta-cells in Kir6.2G132S transgenic mice

Oyama K, Minami K, Ishizaki K, Fuse M, Miki T, Seino S

2006 29 J Orthop Res 2006 06 24 6 1271 1278Prolonged down regulation of specific gene expression in nucleuspulposus cell mediated by RNA interference in vitro

Kakutani K, Nishida K, Uno K, Takada T, Shimomura T, Maeno K,Kurosaka M, Doita M

2006 30 Spine (Phila Pa 1976) 2006 06 31 13 1415 1419Sustained transgene expression in intervertebral disc cells in vivomediated by microbubble-enhanced ultrasound gene therapy

Nishida K, Doita M, Takada T, Kakutani K, Miyamoto H,Shimomura T, Maeno K, Kurosaka M

2006 31 Cancer Res 2006 06 66 12 6395 6404Interleukin-23 and interleukin-27 exert quite different antitumor andvaccine effects on poorly immunogenic melanoma

Oniki S, Nagai H, Horikawa T, Furukawa J, Belladonna ML,Yoshimoto T, Hara I, Nishigori C

2006 32Am J Physiol Lung Cell MolPhysiol

2006 06 290 6 L1078 L1086Ventilator-induced lung injury is reduced in transgenic mice thatoverexpress endothelial nitric oxide synthase

Takenaka K, Nishimura Y, Nishiuma T, Sakashita A, Yamashita T,Kobayashi K, Satouchi M, Ishida T, Kawashima S, Yokoyama M

2006 33Endocrine 2006 06 29 3 485 90

Expression and functional analysis of menin in a multiple endocrineneoplasia type 1 (MEN1) patient with somatic loss of heterozygosity inchromosome 11q13 and unidentified germline mutation of the MEN1

Naito J, Kaji H, Sowa H, Kitazawa R, Kitazawa S, Tsukada T,Hendy GN, Sugimoto T, Chihara K

2006 34Atherosclerosis 2006 06 186 2 402 410

Angiotensin II type 1 receptor blocker telmisartan suppressessuperoxide production and reduces atherosclerotic lesion formation inapolipoprotein E-deficient mice

Takaya T, Kawashima S, Shinohara M, Yamashita T, Toh R,Sasaki N, Inoue N, Hirata K, Yokoyama M

2006 35 J Clin Invest 2006 06 116 6 1494 1505MCP-1 contributes to macrophage infiltration into adipose tissue,insulin resistance, and hepatic steatosis in obesity

Kanda H, Tateya S, Tamori Y, Kotani K, Hiasa K, Kitazawa R,Kitazawa S, Miyachi H, Maeda S, Egashira K, Kasuga M

2006 36 Free Radic Biol Med 2006 05 40 10 1721 1731Thioredoxin protects against joint destruction in a murine arthritismodel

Tsuji G, Koshiba M, Nakamura H, Kosaka H, Hatachi S, KurimotoC, Kurosaka M, Hayashi Y, Yodoi J, Kumagai S

2006 37Nat Genet 2006 05 38 5 589 593

Ablation of PDK1 in pancreatic beta cells induces diabetes as a resultof loss of beta cell mass

Hashimoto N, Kido Y, Uchida T, Asahara S, Shigeyama Y,Matsuda T, Takeda A, Tsuchihashi D, Nishizawa A, Ogawa W,Fujimoto Y, Okamura H, Arden KC, Herrera PL, Noda T, Kasuga

2006 38 Histochem Cell Biol 2006 05 125 5 593 602Expression profile of genes related to osteoclastogenesis in mousegrowth plate and articular cartilage

Kishimoto K, Kitazawa R, Kurosaka M, Maeda S, Kitazawa S

2006 39 Expert Opin Investig Drugs 2006 05 15 5 507 517The potential of clusterin inhibiting antisense oligodeoxynucleotidetherapy for prostate cancer

Miyake H, Hara I, Fujisawa M, Gleave ME

2006 40Proc Natl Acad Sci U S A 2006 05 103 20 7807 12

V1a vasopressin receptors maintain normal blood pressure byregulating circulating blood volume and baroreflex sensitivity

Koshimizu TA, Nasa Y, Tanoue A, Oikawa R, Kawahara Y, KiyonoY, Adachi T, Tanaka T, Kuwaki T, Mori T, Takeo S, Okamura H,Tsujimoto G

2006 41Behav Brain Res 2006 05 169 2 212 9

Cat odour exposure decreases exploratory activity and altersneuropeptide gene expression in CCK(2) receptor deficient mice, butnot in their wild-type littermates

Areda T, Raud S, Philips MA, Innos J, Matsui T, Koks S, Vasar E,Karis A, Asser T

2006 42 Neurosci Lett 2006 05 399 1-2 67 70 Bcl-2 expression mediated by Cre/loxP system in olfactory epithelium Doi K, Nibu K, Okado H, Terashima T

2006 43 Genes Cells 2006 05 11 5 525 530Does mPER2 protein oscillate without its coding mRNA cycling?:post-transcriptional regulation by cell clock

Fujimoto Y, Yagita K, Okamura H

2006 44 Biochem Biophys Res Commun 2006 05 344 1 370 376G-CSF prevents the progression of atherosclerosis and neointimalformation in rabbits

Hasegawa H, Takano H, Ohtsuka M, Ueda K, Niitsuma Y, Qin Y,Tadokoro H, Shiomi M, Komuro I

2006 45 Surgery 2006 05 139 5 646 652Successful 40-hour preservation of the canine small intestine with thecavitary 2-layer method with glutamine supplementation

Li S, Suzuki Y, Fujino Y, Kakinoki K, Yoshikawa T, Tanaka T,Goto N, Tanioka Y, Sakai T, Kuroda Y

2006 46

Cell Metab 2006 04 3 4 267 275Role of hepatic STAT3 in brain-insulin action on hepatic glucoseproduction

Inoue H, Ogawa W, Asakawa A, Okamoto Y, Nishizawa A,Matsumoto M, Teshigawara K, Matsuki Y, Watanabe E, HiramatsuR, Notohara K, Katayose K, Okamura H, Kahn CR, Noda T,Takeda K, Akira S, Inui A, Kasuga M

2006 47 Exp Dermatol 2006 04 15 4 291 299Stat3 activation is required for cell proliferation and tumorigenesis butnot for cell viability in cutaneous squamous cell carcinoma cell lines

Sumita N, Bito T, Nakajima K, Nishigori C

2006 48 J Invest Dermatol 2006 04 126 4 797 807Engagement of CD47 inhibits the contact hypersensitivity responsevia the suppression of motility and B7 expression by Langerhans cells

Yu X, Fukunaga A, Nagai H, Oniki S, Honma N, Ichihashi M,Matozaki T, Nishigori C, Horikawa T

2006 49 Arthroscopy 2006 04 22 4 422 427The structural properties of an osteochondral cylinder graft-recipientconstruct on autologous osteochondral transplantation

Nakaji N, Fujioka H, Nagura I, Kokubu T, Makino T, Sakai H,Kuroda R, Doita M, Kurosaka M

2006 50 Hypertens Res 2006 04 29 4 269 276Transforming growth factor-beta signaling enhancestransdifferentiation of macrophages into smooth muscle-like cells

Ninomiya K, Takahashi A, Fujioka Y, Ishikawa Y, Yokoyama M

2006 51 Oncogene 2006 03 25 10 1437 1445Mitochondrial DNA determines androgen dependence in prostatecancer cell lines

Higuchi M, Kudo T, Suzuki S, Evans TT, Sasaki R, Wada Y,Shirakawa T, Sawyer JR, Gotoh A

2006 52Mol Cell Biol 2006 03 26 5 1743 1753

Functional evolution of the photolyase/cryptochrome protein family:importance of the C terminus of mammalian CRY1 for circadian coreoscillator performance

Chaves I, Yagita K, Barnhoorn S, Okamura H, van der Horst GT,Tamanini F

2006 53 Hepatogastroenterology 2006 03 53 68 179 182Impact of the two-layer method on the quality of isolated pancreaticislets

Takahashi T, Tanioka Y, Matsuda T, Toyama H, Kakinoki K, Li S,Hiraoka K, Fijino Y, Suzuki Y, Kuroda Y

2006 54 Biophys J 2006 03 90 5 1723 1728An X-Ray diffraction study on mouse cardiac cross-bridge function invivo: effects of adrenergic {beta}-stimulation

Toh R, Shinohara M, Takaya T, Yamashita T, Masuda S,Kawashima S, Yokoyama M, Yagi N

2006 55 ASAIO J 2006 03 52 2 140 144Indium-111-oxine-labeled platelet scintigraphic images in theassessment of thrombogenicity in small-caliber prosthetic vascular

Hasegawa T, Okada K, Morimoto Y, Okita Y

2006 56 Biochem Biophys Res Commun 2006 03 341 1 88 93Gene expression profile in the heart of spontaneous dwarf rat: in vivoeffects of growth hormone

Yoshioka S, Takahashi Y, Okimura Y, Takahashi K, Iguchi G, IidaK, Kaji H, Chihara K

2006 57 Cancer 2006 03 106 5 1117 1122 His239Arg SNP of HRAD9 is associated with lung adenocarcinomaManiwa Y, Yoshimura M, Bermudez VP, Okada K, Kanomata N,Ohbayashi C, Nishimura Y, Hayashi Y, Hurwitz J, Okita Y

2006 58 J Dermatol Sci 2006 02 41 2 157 161 Expression of PKC isoforms in human melanocytic cells in situOka M, Nishigori C, Kageshita T, Hsu MY, Penmatcha S, HerlynM

2006 59J Cell Biol 2006 02 172 4 497 504

A novel GTPase, CRAG, mediates promyelocytic leukemia protein-associated nuclear body formation and degradation of expandedpolyglutamine protein

Qin Q, Inatome R, Hotta A, Kojima M, Yamamura H, Hirai H,Yoshizawa T, Tanaka H, Fukami K, Yanagi S

2006 60 J Orthop Sci 2006 01 11 1 75 80Pathogenesis of tendinous xanthoma: histopathological study of theextremities of Watanabe heritable hyperlipidemic rabbits

Nakano A, Kinoshita M, Okuda R, Yasuda T, Abe M, Shiomi M

2006 61 J Clin Forensic Med 2006 01 13 1 26 29 Is sudden death with vitamin C deficiency caused by lack of carnitine? Okamoto M, Ueno Y

2006 62 Spine (Phila Pa 1976) 2006 01 31 1 4 9Effects of cyclic mechanical stress on the production of inflammatoryagents by nucleus pulposus and anulus fibrosus derived cells in vitro

Miyamoto H, Doita M, Nishida K, Yamamoto T, Sumi M, KurosakaM

2006 63 J Struct Biol 2006 01 153 1 64 72In situ detection of specific gene expression during and immediatelyafter transcription at electron microscopic level

Kitazawa S, Kitazawa R

2006 64 Am J Nephrol 2006 00 26 6 552 61Heme-oxygenase upregulation ameliorates angiotensin II-inducedtubulointerstitial injury and salt-sensitive hypertension

Pradhan A, Umezu M, Fukagawa M

2006 65Oncology 2006 00 71 1-2 102 10

Frequent occurrence of abnormal E-cadherin/beta-catenin proteinexpression in advanced gallbladder cancers and its association withdecreased apoptosis

Hirata K, Ajiki T, Okazaki T, Horiuchi H, Fujita T, Kuroda Y

2006 66 Kobe J Med Sci 2006 00 52 5 111 8Carotid artery occlusion and collateral circulation in C57Black/6Jmice detected by synchrotron radiation microangiography

Tamaki M, Kidoguchi K, Mizobe T, Koyama J, Kondoh T, SakuraiT, Kohmura E, Yokono K, Umetani K

2006 67 Kobe J Med Sci 2006 00 52 1-2 27 35Impaired response of perforating arteries to hypercapnia in chronichyperglycemia

Oizumi XS, Akisaki T, Kouta Y, Song XZ, Takata T, Kondoh T,Umetani K, Hirano M, Yamasaki K, Kohmura E, Yokono K, Sakurai

2006 68 Kobe J Med Sci 2006 00 52 5 119 25Sca-1 and Thy-1 accelerate neuron-like differentiation in bonemarrow stromal cells

Mizobe T, Kidoguchi K, Tamaki M, Sasayama T, Kondoh T,Kohmura E

2006 69Kobe J Med Sci 2006 00 52 3-4 85 95

Correlation between Expression of Major Histocompatibility ComplexClass I and That of Antigen Presenting Machineries in Carcinoma CellLines of the Pancreas, Biliary Tract and Colon

Imanishi T, Kamigaki T, Nakamura T, Hayashi S, Yasuda T,Kawasaki K, Takase S, Ajiki T, Kuroda Y

2006 70 Kobe J Med Sci 2006 00 52 4 77 84Ultrastructural Localization of Alpha E-catenin in the Rat SciaticNerve

Murata M, Shibuya Y, Munemoto S, Takeuchi J, Kobayashi M,Suzuki H, Komori T

2006 71 Pathobiology 2006 00 73 1 8 17Significance of Akt phosphorylation on tumor growth and vascularendothelial growth factor expression in human gastric carcinoma

Kobayashi I, Semba S, Matsuda Y, Kuroda Y, Yokozaki H

2006 72 分子消化器病 2006 12 34

号350 353 消化器疾患モデル動物　膵炎モデル動物 安田武生, 上田隆, 黒田嘉和

2006 73 神経外傷 2006 12 291

号27 32

VEGFレセプター拮抗剤(VGA1155)のラット脳凍結損傷モデルにおける脳浮腫に対する治療効果

小山淳二, 三宅茂, 篠山隆司, 近藤威, 甲村英二

2006 74 移植 2006 10 415

号520 520 RNA干渉を用いた椎間板再生への試み

西田康太郎, 角谷賢一朗, 土井田稔, 下村隆敏, 前野耕一郎, 金山修一, 鈴木哲平, 浜村清香, 黒坂昌弘

2006 75 炎症と免疫 2006 10 146

号746 751

【粘膜免疫学の新展開】 FcRnによるIgGを介した管腔内抗原取り込み機構

増田充弘, 吉田優, 鎮西亮, 東健

2006 76 解剖学雑誌 2006 9 813

号106 106 creeping ratの中枢神経系はリーラーフェノタイプを示す 寺島俊雄, 山本達朗, 薛富義, 清野進, 横井伯英

2006 77 実験医学 2006 9 2414号

2116 2121【神経・免疫・内分泌系へ拡がるメンブレントラフィック】　FcRnによるIgG,抗原-IgG複合体の輸送機構

増田充弘, 吉田優, 田中擴址, 東健

2006 78 Diabetes Frontier 2006 8 174

号537 537

1型糖尿病の発症を修飾する遺伝子の解析　KDPラット関連コンジェニック系統を用いた検討

横井伯英, 林千尋, 藤原結花, 清野進

2006 79 神経化学 2006 8 452-3

248 248時間生物学の分子的機構　基礎から臨床まで　概日リズムにおける時間情報の変換　神経インパルスからホルモンへ

岡村均

2006 80 神緑会学術誌 2006 8 22 106 107 凍結保存気管による同種気管移植に関する実験的研究 久松千恵子, 前田貢作

2006 81 日本整形外科学会雑誌 2006 8 808

号S857 S857

椎間板におけるFas-ligandの発現は変性によってどのように変化するか

金山修一, 西田康太郎, 土井田稔, 高田徹, 宇野耕吉, 黒坂昌弘

2006 82蛋白質・核酸・酵素 2006 8 51

10号

1316 1320【ユビキチン-プロテアソーム系とオートファジー　作動機構と病態生理】　ユビキチン系の生理と病態　ユビキチンと代謝応答　動物の概日時計とユビキチン

藤本義人, 岡村均

2006 83 臨床整形外科 2006 6 416

号652 655 整形外科/知ってるつもり　時計遺伝子 岡村均, 増淵悟

2006 84 移植 2006 4 412

号136 137 自家骨軟骨移植術後の移植軟骨の力学的特性

藤岡宏幸, 名倉一成, 国分毅, 牧野健, 坂井宏成, 中路教義, 太田里砂, 黒田良祐, 黒坂昌弘

2006 85 日本脊椎脊髄病学会雑誌 2006 3 171(2/2)

591 591 RNA干渉を椎間板変性研究に応用する試み角谷賢一朗, 西田康太郎, 土井田稔, 鈴木哲平, 金山修一, 前野耕一郎, 下村隆敏, 高田徹, 黒坂昌弘

2006 86 心電図 2006 3 26Su

ppl.S1

41-S1-44

生体時計を基盤とする循環動態調節機構の解明 江本憲昭

2006 87 Geriatric Medicine 2006 3 443

号321 326

【高齢者糖尿病　現状,治療,そして展望】　高齢者糖尿病の薬物療法高齢者糖尿病の治療とその問題点

山田克己, 横野浩一

2006 88 Diabetes Journal 2006 3 341

号39 40 自己免疫性1型糖尿病とインスリンT細胞エピトープ 森山啓明, 永田正男, 横野浩一

2006 89 CAMPUS HEALTH 2006 3 43 2 127 132携帯電話の電磁波がマウス血清一酸化窒素および大脳 iNOS mRNAに与える影響

中田裕久,小川良一,河合美樹,藤平和弘,浦浜憲永,川口　侃,馬場久光

2006 90 日本脊椎脊髄病学会雑誌 2006 3 171(2/2)

588 588ラット尻尾圧迫モデルを用いて作成した変性椎間板における炎症メディエータの産生能(正常椎間板との比較およびマクロファージとの共培養)

濱本秀樹, 宮本裕史, 土井田稔, 高田徹, 西田康太郎, 黒坂昌弘

2006 91 医科学応用研究財団研究報告 2006 2 23 250 253血管内皮リパーゼ(EL)の脂質代謝と動脈硬化形成過程にはたす役割の解明　HDLをターゲットとした動脈硬化動物モデルの作成と治療法

平田健一

2006 92 医学のあゆみ 2006 1 2163

号223 226 【時計遺伝子】　体と時計遺伝子　臓器疾患とリズム 江本憲昭

2006 93 Therapeutic Research 2006 1 271

号69 69

動脈硬化Update 2005　血管内皮リパーゼのHDL代謝と血管病変形成過程における役割

児島陽子, 平田健一, 石田達郎, 安田知行, 横山光宏

2006 94代謝異常治療研究基金研究業績集

2006 1 33 73 78血管内皮リパーゼ(EL)の脂質代謝と動脈硬化、血管障害に果たす役割の解明

平田健一

2006 95 疾患モデル 2006 0 22 70 77高コレステロール血症，冠動脈硬化病変を自然発症するWHHLCA および WHHLMIウサギの特性と動脈硬化病変安定化試験への応用．

塩見 雅志，山田 悟士，田村 敏昌，伊藤 隆

2006 96 ゲノム医科学NOW 2006 0 25 36 関節リウマチの疾患遺伝子 塩沢俊一,柱本照,三浦靖史,駒井浩一郎,塩沢和子

2006 97日本臨床 2006 0 63

suppl.12

228 231 遺伝子診療学 　―遺伝子診断の進歩と遺伝子治療の展望― 柱本照,駒井浩一郎,塩沢俊一

2006 98 糖尿病合併症 2006 0 20 75 70 糖尿病における皮質下血管病変と脳穿通枝動脈の機能障害について 櫻井　孝

2005 1 Asian J Androl 2005 12 7 4 369 373Erythropoietin gene transfer into rat testes by in vivo electropo-ration may reduce the risk of germ cell loss caused by cryptorchidism

Dobashi M, Goda K, Maruyama H, Fujisawa M

2005 2 Transplant Proc 2005 12 37 10 4630 4633Donor leukocytes combined with delayed immunosupressive drugtherapy prolong limb allograft survival

Matsumoto T, Kanatani T, Lanzetta M, Fujioka H, Kurosaka M,McCaughan GW, Bishop GA

2005 3 Urology 2005 12 66 6 1239 1244Antitumor effects of etodolac, a selective cyclooxygenase-II inhibitor,against human prostate cancer cell lines in vitro and in vivo

Shigemura K, Shirakawa T, Wada Y, Kamidono S, Fujisawa M,Gotoh A

2005 4 Genes Cells 2005 12 10 12 1127 1137The role of transcriptional coactivator TRAP220 in myelomonocyticdifferentiation

Urahama N, Ito M, Sada A, Yakushijin K, Yamamoto K, OkamuraA, Minagawa K, Hato A, Chihara K, Roeder RG, Matsui T

2005 5 Artif Organs 2005 11 29 11 880 886Thrombin-free fibrin coating on small caliber vascular prostheses hashigh antithrombogenicity in rabbit model

Hasegawa T, Okada K, Takano Y, Hiraishi Y, Okita Y

2005 6 Cardiovasc Res 2005 11 68 2 249 258Xenogenic smooth muscle cell immunization reduces neointimalformation in balloon-injured rabbit carotid arteries

Shinohara M, Kawashima S, Yamashita T, Takaya T, Toh R,Ishida T, Ueyama T, Inoue N, Hirata K, Yokoyama M

2005 7 Cell Metab 2005 11 2 5 297 307Light activates the adrenal gland: timing of gene expression andglucocorticoid release

Ishida A, Mutoh T, Ueyama T, Bando H, Masubuchi S, NakaharaD, Tsujimoto G, Okamura H

2005 8 Horm Metab Res 2005 10 37 10 589 592Statins modulate the levels of osteoprotegerin/receptor activator ofNFkappaB ligand mRNA in mouse bone-cell cultures

Kaji H, Kanatani M, Sugimoto T, Chihara K

2005 9Brain Dev 2005 10 27 7 488 493

Intraperitoneal administration of phosphorothioate antisenseoligodeoxynucleotide against splicing enhancer sequence inducedexon skipping in dystrophin mRNA expressed in mdx skeletal muscle

Takeshima Y, Yagi M, Wada H, Matsuo M

2005 10 Exp Anim 2005 10 54 5 413 419Discrimination of Recent Ischemic Myocardial Changes in WHHLMIRabbits from the Findings of Postmortem Degeneration

Ito T, Yamada S, Tamura T, Shiomi M

2005 11 Am J Transplant 2005 09 5 9 2135 2142Detailed analysis of mucosal restoration of the small intestine afterthe cavitary two-layer cold storage method

Yoshikawa T, Suzuki Y, Fujino Y, Kakinoki K, Li S, Goto T,Tanaka T, Matsumoto I, Sakai T, Tanioka Y, Yokozaki H, Kuroda

2005 12 Neuropathology 2005 09 25 3 274 279Application trials of in situ hybridization at the electron microscopiclevel

Kitazawa S, Kondo T, Kitazawa R

2005 13 Transplantation 2005 09 80 6 738 742Possibility of islet transplantation from a nonheartbeating donorpancreas resuscitated by the two-layer method

Tanaka T, Suzuki Y, Tanioka Y, Sakai T, Kakinoki K, Goto T, Li S,Yoshikawa T, Matsumoto I, Fujino Y, Kuroda Y

2005 14 Ann Otol Rhinol Laryngol 2005 08 114 8 629 633Adenovirus-mediated gene transfer in olfactory epithelium andolfactory bulb: a long-term study

Doi K, Nibu K, Ishida H, Okado H, Terashima T

2005 15 Neurosci Lett 2005 08 383 3 215 219Tyramine-immunoreactive neuronal structures in the rat brain:abundance in the median eminence of the mediobasal hypothalamus

Kitahama K, Araneda S, Geffard M, Sei H, Okamura H

2005 16J Chromatogr B Analyt TechnolBiomed Life Sci

2005 08 823 1 37 43Detection of phosphatidylcholine oxidation products in rat heart usingquadrupole time-of-flight mass spectrometry

Adachi J, Yoshioka N, Sato M, Nakagawa K, Yamamoto Y, UenoY

2005 17 J Allergy Clin Immunol 2005 08 116 2 397 402Responsiveness to autologous sweat and serum in cholinergicurticaria classifies its clinical subtypes

Fukunaga A, Bito T, Tsuru K, Oohashi A, Yu X, Ichihashi M,Nishigori C, Horikawa T

2005 18 Anticancer Res 2005 07 25 4 2757 2760Recombinant interleukin-2 enhanced the antitumor effect ofADV/RSV-HSV-tk/ACV therapy in a murine bladder cancer model

Terao S, Shirakawa T, Goda K, Kamidono S, Fujisawa M, Gotoh A

2005 19 Acta Anaesthesiol Scand 2005 07 49 6 819 826Effects of phosphodiesterase-III inhibitors on sevoflurane-inducedimpairment of rat diaphragmatic function

Uesugi T, Mikawa K, Nishina K, Kodama SI, Obara H

2005 20 Exp Eye Res 2005 07 81 1 48 56Long-term glial reactivity in rat retinas ipsilateral and contralateral toexperimental glaucoma

Kanamori A, Nakamura M, Nakanishi Y, Yamada Y, Negi A

2005 21Arch Otolaryngol Head NeckSurg

2005 07 131 7 630 634 A replication-selective adenoviral vector for head and neck cancers Tanaka H, Shirakawa T, Zhang Z, Hamada K, Gotoh A, Nibu K

2005 22 Oncogene 2005 07 24 32 5108 5118Methylation adjacent to negatively regulating AP-1 site reactivatesTrkA gene expression during cancer progression

Fujimoto M, Kitazawa R, Maeda S, Kitazawa S

2005 23 Cancer Res 2005 07 65 14 6006 60108-Oxoguanine formation induced by chronic UVB exposure makesOgg1 knockout mice susceptible to skin carcinogenesis

Kunisada M, Sakumi K, Tominaga Y, Budiyanto A, Ueda M,Ichihashi M, Nakabeppu Y, Nishigori C

2005 24 Life Sci 2005 06 77 6 670 682Chylomicron remnants regulate early growth response factor-1 invascular smooth muscle cells

Takahashi Y, Fujioka Y, Takahashi T, Domoto K, Takahashi A,Taniguchi T, Ishikawa Y, Yokoyama M

2005 25 Hypertension 2005 06 45 6 1145 1152Dual ECE/NEP inhibition on cardiac and neurohumoral function duringthe transition from hypertrophy to heart failure in rats

Emoto N, Raharjo SB, Isaka D, Masuda S, Adiarto S, Jeng AY,Yokoyama M

2005 26 Cardiovasc Res 2005 06 66 3 594 600Increased expression of endothelial lipase in rat models ofhypertension

Shimokawa Y, Hirata K, Ishida T, Kojima Y, Inoue N, QuertermousT, Yokoyama M

2005 27 J Immunol 2005 06 174 11 6934 6942The spermatogenic Ig superfamily/synaptic cell adhesion moleculemast-cell adhesion molecule promotes interaction with nerves

Furuno T, Ito A, Koma Y, Watabe K, Yokozaki H, Bienenstock J,Nakanishi M, Kitamura Y

2005 28 Transplantation 2005 06 79 11 1516 1521Superiority of the two-layer method before islet isolation confirmedby in vivo viability assessment

Kakinoki K, Fujino Y, Suzuki Y, Li S, Tanioka Y, Sakai T, KurodaY

2005 29 Kidney Int 2005 04 67 4 1410 1419Circadian clock genes directly regulate expression of the Na+/H+exchanger NHE3 in the kidney

Saifur Rohman M, Emoto N, Nonaka H, Okura R, Nishimura M,Yagita K, van der Horst GT, Matsuo M, Okamura H, Yokoyama M

2005 30J Androl 2005 03 26 2 281 288

Overexpression of endothelial nitric oxide synthase in transgenic miceaccelerates testicular germ cell apoptosis induced by experimentalcryptorchidism

Ishikawa T, Kondo Y, Goda K, Fujisawa M

2005 31

Commentary to the InternationalAtherosclerosis Society IASWebsite(http://www.athero.org/comm-index.asp#1)

2005 03Anti-Atherosclerotic Effects Of Statins, Lessons From Animal ModelOf Spontaneous Atherosclerosis

Shiomi M, Ito T

2005 32 Int J Mol Med 2005 00 15 6 1033 1039 Melanin-concentrating hormone enhances sucrose intakeSakamaki R, Uemoto M, Inui A, Asakawa A, Ueno N, Ishibashi C,Hirono S, Yukioka H, Kato A, Shinfuku N, Kasuga M, Katsuura G

2005 33 Int J Mol Med 2005 00 15 6 1041 1043Intracerebroventricularly administered urocortin inhibits gastricemptying in mice

Nagata T, Uemoto M, Yuzuriha H, Asakawa A, Inui A, Fujimiya M,Sakamaki R, Kasuga M, Shinfuku N

2005 34 J Neurosci 2005 00 25 19 4719 4724Mouse Period1 (mPER1) acts as a circadian adaptor to entrain theoscillator to environmental light/dark cycles by regulating mPER2

Masubuchi S, Kataoka N, Sassone-Corsi P, Okamura H

2005 35 J Biol Chem 2005 00 280 13 12231 12238The role of the regulatory subunit of fission yeast calcineurin for invivo activity and its relevance to FK506 sensitivity

Sio SO, Suehiro T, Sugiura R, Takeuchi M, Mukai H, Kuno T

2005 36 Trop Med Health 2005 00 33 1 7 11Epidemiological study on Centrocestus armatus metacercariae in theChikusa River, Hyogo Prefecture, Japan

Kimura D, Uga S

2005 37 Psychopharmacology (Berl) 2005 00 181 2 347 357Targeted invalidation of CCK(2) receptor gene induces anxiolytic-likeaction in light-dark exploration, but not in fear conditioning test

Raud S, Innos J, Abramov U, Reimets A, Koks S, Soosaar A,Matsui T, Vasar E

2005 38 Alcohol Alcohol 2005 00 40 3 176 180Differences in ethanol ingestion between cholecystokinin-A receptordeficient and -B receptor deficient mice

Miyasaka K, Hosoya H, Takano S, Ohta M, Sekime A, Kanai S,Matsui T, Funakoshi A

2005 39 Biomed Res 2005 00 26 2 43 49Expression of ubiquitin-related enzymes in the suprachiasmaticnucleus with special reference to ubiquitin carboxy-terminal hydrolase

Dong X, Yagita K, Zhang J, Okamura H

2005 40 Methods Enzymol 2005 00 403 408 419 Physical and functional interaction of noc2/rab3 in exocytosis Shibasaki T, Seino S

2005 41 Mol Cell Biol 2005 00 25 5 1912 1921 Role of cyclic mPer2 expression in the mammalian cellular clock Yamamoto Y, Yagita K, Okamura H

2005 42 BJU Int 2005 00 95 6 895 897Assessment of microheterogeneity of blood flow in the rat urinarybladder by high-resolution digital radiography

Kimura T, Yamamoto T, Sone A, Takenaka A, Fujisawa M

2005 43 Tohoku J Exp Med 2005 00 205 2 103 113Differential expression of proteinase inhibitor-9 and granzyme BmRNAs in activated immunocompetent cells

Horie O, Saigo K, Murayama T, Ryo R

2005 44 Kobe J Med Sci 2005 00 51 5-6 67 72Detection of cancer cells in the peripheral blood and lung of miceafter transplantation of human adenoid cystic carcinoma

Komatsubara H, Umeda M, Ojima Y, Minamikawa T, Komori T

2005 45Kobe J Med Sci 2005 00 51 5-6 73 83

Neuroprotective effect of D-fructose-1,6-bisphosphate against beta-amyloid induced neurotoxicity in rat hippocampal organotypic sliceculture: involvement of PLC and MEK/ERK signaling pathways

Song X, Wu B, Takata T, Wang X, Oizumi XS, Akisaki T, YokonoK, Sakurai T

2005 46 Kobe J Med Sci 2005 00 51 5-6 85 93Molecular oscillation of Per1 and Per2 genes in the rodent brain: an insitu hybridization and molecular biological study

Matsui D, Takekida S, Okamura H

2005 47Bulletin Of Health SciencesKobe

2005 00 21 1 11Effects of strech on muscle regeneration in the damaged mousesoleus muscle after eccentric exercise

Matsubara T, Miki A

2005 48Photomed Laser Surg 2005 00 23 1 47 51

Experimental study on the morphological and functional recoveryfollowing partial glossectomy in rabbits: a comparison between CO2laser and electrocautery

Ishii J, Kuriyama T, Komori T

2005 49 Eur J Neurosci 2005 00 21 9 2586 2592Changes in reelin expression in the mouse olfactory bulb afterchemical lesion to the olfactory epithelium

Okuyama-Yamamoto A, Yamamoto T, Miki A, Terashima T

2005 50 Surg Endosc 2005 00 19 2 226 228Comparative study of electrothermal bipolar vessel sealer andultrasonic coagulating shears in laparoscopic colectomy

Takada M, Ichihara T, Kuroda Y

2005 51 Gut 2005 00 54 1 18 24Stomach regulates energy balance via acylated ghrelin and desacylghrelin

Asakawa A, Inui A, Fujimiya M, Sakamaki R, Shinfuku N, Ueta Y,Meguid MM, Kasuga M

2005 52 Ophthalmologica 2005 00 219 1 1 10 Diabetes mellitus as a risk factor for glaucomatous optic neuropathy Nakamura M, Kanamori A, Negi A

2005 53J Clin Invest 2005 00 115 1 138 145

PKClambda regulates glucose-induced insulin secretion throughmodulation of gene expression in pancreatic beta cells

Hashimoto N, Kido Y, Uchida T, Matsuda T, Suzuki K, Inoue H,Matsumoto M, Ogawa W, Maeda S, Fujihara H, Ueta Y, UchiyamaY, Akimoto K, Ohno S, Noda T, Kasuga M

2005 54Atherosclerosis 2005 00 178 2 287 294

Atheroma stabilizing effects of simvastatin due to depression ofmacrophages or lipid accumulation in the atheromatous plaques ofcoronary plaque-prone WHHL rabbits

Shiomi M, Yamada S, Ito T

2005 55J Biol Chem 2005 00 280 13 12867 12875

Role of Kruppel-like factor 15 (KLF15) in transcriptional regulation ofadipogenesis

Mori T, Sakaue H, Iguchi H, Gomi H, Okada Y, Takashima Y,Nakamura K, Nakamura T, Yamauchi T, Kubota N, Kadowaki T,Matsuki Y, Ogawa W, Hiramatsu R, Kasuga M

2005 56Knee Surg Sports TraumatolArthrosc

2005 00 13 2 101 106The load of an implanted graft during and after fixation in anteriorcruciate ligament reconstruction

Yoshihara Y, Yoshiya S, Kurosaka M, Yamamoto T, Kuroda R,Muratsu H

2005 57 Nat Med 2005 00 11 2 175 182Deletion of Cdkn1b ameliorates hyperglycemia by maintainingcompensatory hyperinsulinemia in diabetic mice

Uchida T, Nakamura T, Hashimoto N, Matsuda T, Kotani K,Sakaue H, Kido Y, Hayashi Y, Nakayama KI, White MF, Kasuga M

2005 58 J Clin Invest 2005 00 115 2 291 301Adipocytes from Munc18c-null mice show increased sensitivity toinsulin-stimulated GLUT4 externalization

Kanda H, Tamori Y, Shinoda H, Yoshikawa M, Sakaue M,Udagawa J, Otani H, Tashiro F, Miyazaki J, Kasuga M

2005 59 Kobe J Med Sci 2005 00 51 3-4 35 40 N-/R-cadherin expression in dorsal root ganglia and spinal cordShibuya Y, Takeuchi J, Kobayashi M, Murata M, Munemoto S,Yokoo S, Umeda M, Komori T

2005 60 Anesth Analg 2005 00 100 3 810 816 Attenuation of acute lung injury with propofol in endotoxemia Takao Y, Mikawa K, Nishina K, Obara H

2005 61Mol Cell Biol 2005 00 25 6 2191 2199

Congenital semilunar valvulogenesis defect in mice deficient inphospholipase C epsilon

Tadano M, Edamatsu H, Minamisawa S, Yokoyama U, Ishikawa Y,Suzuki N, Saito H, Wu D, Masago-Toda M, Yamawaki-Kataoka Y,Setsu T, Terashima T, Maeda S, Satoh T, Kataoka T

2005 62 Transplant Proc 2005 00 37 1 220 222Augmentation of tissue ATP level during digestion usingpreoxygenated perfluorocarbon results in high islet yield-new strategy

Tanioka Y, Tanaka T, Gotoh T, Kakinoki K, Li S, Yoshikawa T,Sakai T, Fujino Y, Suzuki Y, Kuroda Y

2005 63 Diabetes 2005 00 54 4 1056 1063Distinct effects of glucose-dependent insulinotropic polypeptide andglucagon-like peptide-1 on insulin secretion and gut motility

Miki T, Minami K, Shinozaki H, Matsumura K, Saraya A, Ikeda H,Yamada Y, Holst JJ, Seino S

2005 64 Biochem Biophys Res Commun 2005 00 327 3 920 926 Role of Kruppel-like factor 15 in PEPCK gene expression in the liverTeshigawara K, Ogawa W, Mori T, Matsuki Y, Watanabe E,Hiramatsu R, Inoue H, Miyake K, Sakaue H, Kasuga M

2005 65Anesth Analg 2005 00 100 4 964 971

The efficacy of fluorocarbon, surfactant, and their combination forimproving acute lung injury induced by intratracheal acidified infantformula

Nishina K, Mikawa K, Takao Y, Obara H

2005 66 Br J Dermatol 2005 00 152 3 435 443Retinoic acid suppresses telomerase activity in HSC-1 humancutaneous squamous cell carcinoma

Kunisada M, Budiyanto A, Bito T, Nishigori C, Ueda M

2005 67 Free Radic Res 2005 00 39 3 299 304 Oxysterols increase in diabetic rats Yoshioka N, Adachi J, Ueno Y, Yoshida K

2005 68 脳循環代謝 2005 12 174

号273 274

シナプス伝達から見た虚血負荷に対する耐性獲得　アデノシンおよびアデノシン代謝産物の役割

相原英夫, 溝部敬, 木戸口慶司, 玉木正裕, 近藤威, 甲村英二

2005 69 循環器専門医 2005 9 132

号257 263

心血管病のトランスレーショナルリサーチ　エンドセリンシステム　基礎研究の結果をふまえたトランスレーショナルリサーチ

江本憲昭, 横山光宏

2005 70 日本生殖内分泌学会雑誌 2005 9 10 37 42 マウス造精機能障害モデルにおけるTRAIL発現抑制の効果合田上政, 後藤章暢, 白川利朗, 寺尾秀治, 土橋正樹, 岡田弘,守殿貞夫, 藤澤正人

2005 71 日本癌学会総会記事 2005 964回

397 397慢性紫外線(UVB)照射による皮膚8-oxoguanine形成はOgg1ノックアウトマウスにおいて皮膚発癌発生率を有意に増加させる

国定充, 作見邦彦, 冨永洋平, 上田正登, 市橋正光, 中別府雄作,錦織千佳子

2005 72 神緑会学術誌 2005 8 21 153 155多血小板血漿(Platelet Rich Plasma)のin vitroにおける兎半月板細胞に対する効果

黒田良祐, 石田一成, 黒坂昌弘

2005 73 臨床免疫 2005 8 442

号141 147

【臓器特異的自己免疫疾患の発症機構とその制御】　1型糖尿病における自己抗原反応性T細胞

森山啓明, 永田正男, 横野浩一

2005 74 アニテックス 2005 7 17 4 125 128WHHL/WHHLMIウサギのメタボリックシンドロームに関連する病態について

塩見 雅志，伊藤 隆

2005 75 日本耳鼻咽喉科学会会報 2005 5 1085

増595 595

COX-2臓器特異性プロモーターを組み込んだ増殖型アデノウイルスベクターによる頭頸部扁平上皮癌に対する治療法の検討

田中博紀, 丹生健一, ZhangZhujun, 白川利朗, 後藤彰暢

2005 76中部日本整形外科災害外科学会雑誌

2005 3 482

号267 268 骨軟骨移植術における移植軟骨の力学的特性 中路教義, 藤岡宏幸, 国分毅, 牧野健, 黒坂昌弘

2005 77 Clinical Calcium 2005 2 153

号418 422 【腰痛の管理】　腰痛性疾患に対する分子生物学的アプローチ

西田康太郎, 土井田稔, 高田徹, 下村隆敏, 前野耕一郎, 角谷賢一朗, 宮本裕史, 黒坂昌弘

2005 78 ゲノム医学 2005 2 51

号33 38

【関節リウマチとゲノム】　Linkage解析によるRA関連遺伝子　疾患候補遺伝子としてのAngiopoietin-1

柱本照, 酒井千菜, 三浦靖史, 駒井浩一郎, 塩澤和子, 塩澤俊一

2005 79 炎症と免疫 2005 0 13 2 195 204 酸化ストレスと自己免疫疾患 熊谷俊一，信原由実子，栗本千代

2005 80 臨床検査 2005 0 49 2 169 176 酸化ストレスと自己免疫疾患 熊谷俊一,辻　剛，栗本千代

2004 1 J Cell Physiol 2004 10 201 1 17 25Thyroid hormone stimulates osteoclast differentiation by a mechanismindependent of RANKL-RANK interaction

Kanatani M, Sugimoto T, Sowa H, Kobayashi T, Kanzawa M,Chihara K

2004 2 J Gastroenterol Hepatol 2004 08 19 8 866 872 Apoptotic pathway related to oval cell proliferationYano Y, Hayashi Y, Teramoto T, Nakaji M, Nagy P, Ninomiya T,Wada A, Hirai M, Kim SR, Seo Y, Yoon S, Kasuga M

2004 3 Hepatogastroenterology 2004 07 51 58 925 927Retroperitoneoscopic laparoscopic distal pancreatectomy with spleensalvage

Takada M, Ichihara T, Toyama H, Suzuki Y, Kuroda Y

2004 4 Clin Cancer Res 2004 07 10 13 4342 4348A cox-2 promoter-based replication-selective adenoviral vector totarget the cox-2-expressing human bladder cancer cells

Shirakawa T, Hamada K, Zhang Z, Okada H, Tagawa M, KamidonoS, Kawabata M, Gotoh A

2004 5Transplantation 2004 07 78 1 78 82

Objective and rapid assessment of pancreas graft viability using 31P-nuclear magnetic resonance spectroscopy combined with two- layercold storage method

Yoshikawa T, Suzuki Y, Kanashiro M, Li S, Goto T, Tanaka T,Kakinoki K, Sakai T, Tanioka Y, Fujino Y, Kuroda Y

2004 6Biol Pharm Bull 2004 07 27 7 1070 1074

Antiproliferative activity of Rhinacanthus nasutus (L.) KURZ extractsand the active moiety, Rhinacanthin C

Gotoh A, Sakaeda T, Kimura T, Shirakawa T, Wada Y, Wada A,Kimachi T, Takemoto Y, Iida A, Iwakawa S, Hirai M, Tomita H,Okamura N, Nakamura T, Okumura K

2004 7Surgery 2004 06 135 6 642 648

Protection against ischemia/reperfusion injury by the cavitary two-layer method in canine small intestinal transplantation with reductionof reactive oxygen species

Kakinoki K, Fujino Y, Suzuki Y, Li S, Yoshikawa T, Tanioka Y, KuY, Kuroda Y

2004 8Mol Biol Cell 2004 06 15 6 2920 2931

Loss of Apm1, the micro1 subunit of the clathrin-associated adaptor-protein-1 complex, causes distinct phenotypes and synthetic lethalitywith calcineurin deletion in fission yeast

Kita A, Sugiura R, Shoji H, He Y, Deng L, Lu Y, Sio SO,Takegawa K, Sakaue M, Shuntoh H, Kuno T

2004 9 Transplant Proc 2004 06 36 5 1534 1536 Augmentation of interleukin-10 in pancreatic islets after brain death Takada M, Toyama H, Tanaka T, Suzuki Y, Kuroda Y

2004 10 J Biol Chem 2004 06 279 26 27774 27780Down-regulation of melanogenesis by phospholipase D2 throughubiquitin proteasome-mediated degradation of tyrosinase

Kageyama A, Oka M, Okada T, Nakamura S, Ueyama T, Saito N,Hearing VJ, Ichihashi M, Nishigori C

2004 11J Am Coll Cardiol 2004 06 43 12 2337 2347

Transplantation of cardiotrophin-1-expressing myoblasts to the leftventricular wall alleviates the transition from compensatoryhypertrophy to congestive heart failure in Dahl salt-sensitive

Toh R, Kawashima S, Kawai M, Sakoda T, Ueyama T, Satomi-Kobayashi S, Hirayama S, Yokoyama M

2004 12 Biochem Biophys Res Commun 2004 05 317 4 1144 1148In vivo transgene expression using an adenoviral tetracycline-regulated system with neuron-specific enolase promoter

Bhattacharjee AK, Ueyama T, Kondoh T, Hayashi S,Abouelfetouh A, Sakai N, Saito N, Kohmura E

2004 13Anesth Analg 2004 05 98 5 1273 1279

Intratracheal application of recombinant surfactant protein-Csurfactant to rabbits attenuates acute lung injury induced byintratracheal acidified infant formula

Mikawa K, Nishina K, Takao Y, Obara H

2004 14 Heart Vessels 2004 05 19 3 132 136Oral taurine supplementation prevents fructose-induced hypertensionin rats

Harada H, Tsujino T, Watari Y, Nonaka H, Emoto N, Yokoyama M

2004 15 Hepatogastroenterology 2004 05 51 57 672 674A recurrent case of an early gallbladder carcinoma after laparoscopiccholecystectomy

Sano T, Ajiki T, Hirata K, Okazaki T, Fujino Y, Suzuki Y,Takeyama Y, Kuroda Y, Onoyama H

2004 16 Spine (Phila Pa 1976) 2004 05 29 10 1089 1092Interleukin-6 production is upregulated by interaction between disctissue and macrophages

Takada T, Nishida K, Doita M, Miyamoto H, Kurosaka M

2004 17 Exp Anim 2004 04 53 2 159 163Age-related changes in serum/plasma biochemical parameters ofWHHLMI rabbits

Yamada S, Ito T, Tamura T, Shiomi M

2004 18 Mech Dev 2004 04 121 4 387 395Endothelin-1 regulates the dorsoventral branchial arch patterning inmice

Ozeki H, Kurihara Y, Tonami K, Watatani S, Kurihara H

2004 19J Immunol 2004 04 172 7 4091 4099

SRC homology 2 domain-containing protein tyrosine phosphatasesubstrate 1 regulates the migration of langerhans cells from theepidermis to draining lymph nodes

Fukunaga A, Nagai H, Noguchi T, Okazawa H, Matozaki T, Yu X,Lagenaur CF, Honma N, Ichihashi M, Kasuga M, Nishigori C,Horikawa T

2004 20 Neuroreport 2004 04 15 6 945 947 Notch expression in developing olfactory neuroepithelium Doi K, Ishida H, Nibu K

2004 21 Biochem Biophys Res Commun 2004 04 316 3 628 635 An anti-proliferative gene BTG1 regulates angiogenesis in vitroIwai K, Hirata K, Ishida T, Takeuchi S, Hirase T, Rikitake Y,Kojima Y, Inoue N, Kawashima S, Yokoyama M

2004 22 Mol Cell Biol 2004 03 24 6 2324 2331Lub1 participates in ubiquitin homeostasis and stress response viamaintenance of cellular ubiquitin contents in fission yeast

Ogiso Y, Sugiura R, Kamo T, Yanagiya S, Lu Y, Okazaki K,Shuntoh H, Kuno T

2004 23 Urology 2004 03 63 3 613 618Development of human chorionic gonadotropin subunit-betapromoter-based toxic gene therapy for testicular cancer

Shirakawa T, Gotoh A, Zhang Z, Kao C, Chung LW, Gardner TA

2004 24 Life Sci 2004 03 74 17 2097 2109Up-regulation of mitochondrial transcription factor 1 mRNA levels byGH in VSMC

Yoshioka S, Okimura Y, Takahashi Y, Iida K, Kaji H, Matsuo M,Chihara K

2004 25 Carcinogenesis 2004 03 25 3 389 397IFN-alpha prevents the growth of pre-neoplastic lesions and inhibitsthe development of hepatocellular carcinoma in the rat

Nakaji M, Yano Y, Ninomiya T, Seo Y, Hamano K, Yoon S, KasugaM, Teramoto T, Hayashi Y, Yokozaki H

2004 26 World J Surg 2004 03 28 3 277 282Changes in extrathymic T cells in the liver and intestinalintraepithelium in mice with obstructive jaundice

Ueno K, Ajiki T, Watanabe H, Abo T, Takeyama Y, Onoyama H,Kuroda Y

2004 27 Cryobiology 2004 02 48 1 1 7 Cryopreservation of protozoan parasites Miyake Y, Karanis P, Uga S

2004 28Nat Med 2004 02 10 2 168 174

Role of STAT-3 in regulation of hepatic gluconeogenic genes andcarbohydrate metabolism in vivo

Inoue H, Ogawa W, Ozaki M, Haga S, Matsumoto M, Furukawa K,Hashimoto N, Kido Y, Mori T, Sakaue H, Teshigawara K, Jin S,Iguchi H, Hiramatsu R, LeRoith D, Takeda K, Akira S, Kasuga M

2004 29 Dev Dyn 2004 02 229 2 400 410Ror2 knockout mouse as a model for the developmental pathology ofautosomal recessive Robinow syndrome

Schwabe GC, Trepczik B, Suring K, Brieske N, Tucker AS,Sharpe PT, Minami Y, Mundlos S

2004 30Genes Cells 2004 01 9 1 71 82

Pmr1, a P-type ATPase, and Pdt1, an Nramp homologue,cooperatively regulate cell morphogenesis in fission yeast: theimportance of Mn2+ homeostasis

Maeda T, Sugiura R, Kita A, Saito M, Deng L, He Y, Yabin L,Fujita Y, Takegawa K, Shuntoh H, Kuno T

2004 31J Urol 2004 01 171 1 426 430

Over expression of CD44V8-10 in human bladder cancer cellsdecreases their interaction with hyaluronic acid and potentiates theirmalignant progression

Muramaki M, Miyake H, Kamidono S, Hara I

2004 32 Brain Res Dev Brain Res 2004 01 148 1 89 96Reelin-expressing neurons in the anterior commissure and corpuscallosum of the rat

Misaki K, Kikkawa S, Terashima T

2004 33 Atherosclerosis 2004 01 172 1 21 29Intramuscular gene transfer of interleukin-10 cDNA reducesatherosclerosis in apolipoprotein E-knockout mice

Namiki M, Kawashima S, Yamashita T, Ozaki M, Sakoda T, InoueN, Hirata K, Morishita R, Kaneda Y, Yokoyama M

2004 34Crit Care Med 2004 01 32 1 209 216

Efficacy of partial liquid ventilation in improving acute lung injuryinduced by intratracheal acidified infant formula: determination ofoptimal dose and positive end-expiratory pressure level

Mikawa K, Nishina K, Takao Y, Obara H

2004 35 Kobe J Med Sci 2004 01 50 1 21 30PDGF-a Receptor Expression Following Hypoxic-Ischemic Injury inthe Neonatal Rat Brain

Morioka I, Tsumeishi S, Takada S, Matsuo M

2004 36 Curr Eye Res 2004 01 28 1 47 54Diabetes has an additive effect on neural apoptosis in rat retina withchronically elevated intraocular pressure

Kanamori A, Nakamura M, Mukuno H, Maeda H, Negi A

2004 37 Arthroscopy 2004 00 20 8 837 840 The effect of graft sizing on osteochondral transplantationMakino T, Fujioka H, Terukina M, Yoshiya S, Matsui N, KurosakaM

2004 38 J Biol Chem 2004 00 279 43 45085 45092Endothelial lipase modulates susceptibility to atherosclerosis inapolipoprotein-E-deficient mice

Ishida T, Choi SY, Kundu RK, Spin J, Yamashita T, Hirata K,Kojima Y, Yokoyama M, Cooper AD, Quertermous T

2004 39 Exp Dermatol 2004 00 13 10 613 620In vivo elimination of CD25+ regulatory T cells leads to tumorrejection of B16F10 melanoma, when combined with interleukin-12

Nagai H, Horikawa T, Hara I, Fukunaga A, Oniki S, Oka M,Nishigori C, Ichihashi M

2004 40 Curr Opin Pharmacol 2004 00 4 2 110 115 Oxidant stress and atherosclerosis Yokoyama M

2004 41 Biochem Biophys Res Commun 2004 00 320 3 689 695Methylglyoxal induces apoptosis through activation of p38 MAPK inrat Schwann cells

Fukunaga M, Miyata S, Liu BF, Miyazaki H, Hirota Y, Higo S,Hamada Y, Ueyama S, Kasuga M

2004 42 J Biol Chem 2004 00 279 48 50102 50109The receptor tyrosine kinase Ror2 associates with and is activated bycasein kinase Iepsilon

Kani S, Oishi I, Yamamoto H, Yoda A, Suzuki H, Nomachi A,Iozumi K, Nishita M, Kikuchi A, Takumi T, Minami Y

2004 43 Spine (Phila Pa 1976) 2004 00 29 21 2365 2369Fas-ligand expression on nucleus pulposus begins in developingembryo

Inui Y, Nishida K, Doita M, Takada T, Miyamoto H, Yoshiya S,Kurosaka M

2004 44 Kobe J Med Sci 2004 00 50 101 109 Molecular signals of mammalian circadian clock Zhang J, Dong X, Fujimoto Y, Okamura H

2004 45J Atheroscler Thromb 2004 00 11 4 184 189

Correlation of vulnerable coronary plaques to sudden cardiac events.Lessons from a myocardial infarction-prone animal model (theWHHLMI rabbit)

Shiomi M, Ito T, Yamada S, Kawashima S, Fan J

2004 46 Brain Res 2004 00 1022 1-2 195 204Akt is activated via insulin/IGF-1 receptor in rat retina with episcleralvein cauterization

Kanamori A, Nakamura M, Nakanishi Y, Nagai A, Mukuno H,Yamada Y, Negi A

2004 47Oral Surg Oral Med Oral PatholOral Radiol Endod

2004 00 98 2 211 216Establishment and characterization of metastasizing cell lines from aheterotransplanted human adenoid cystic carcinoma

Umeda M, Komatsubara H, Ojima Y, Minamikawa T, Shibuya Y,Yokoo S, Komori T

2004 48 J Bone Miner Res 2004 00 19 9 1411 14191 alpha,25 dihydroxyvitamin D3 rapidly regulates the mouseosteoprotegerin gene through dual pathways

Kondo T, Kitazawa R, Maeda S, Kitazawa S

2004 49 J Gene Med 2004 00 6 8 869 876Adenoviral-mediated HGF expression inhibits germ cell apoptosis inrats with cryptorchidism

Goda K, Fujisawa M, Shirakawa T, Dobashi M, Shiota G, ZhangZJ, Gotoh A, Kamidono S

2004 50 Acta Otolaryngol Suppl 2004 00 553 90 94Quantitative analysis of expression of NeuroD, GAP43 and receptortyrosine kinase B in developing mouse olfactory neuroepithelium

Yasui R, Hasegawa M, Doi K, Shimizu K, Ohtuski N, Ishida H,Nibu K

2004 51 Pediatr Nephrol 2004 00 19 8 844 852Role of p38 MAP kinase pathway in a toxin-induced model ofhemolytic uremic syndrome

Fu XJ, Iijima K, Nozu K, Hamahira K, Tanaka R, Oda T,Yoshikawa N, Matsuo M

2004 52 Neurosci Res 2004 00 50 4 467 474Glycolysis regulates the induction of lactate utilization for synapticpotentials after hypoxia in the granule cell of guinea pig hippocampus

Takata T, Yang B, Sakurai T, Okada Y, Yokono K

2004 53 Brain Res 2004 00 1029 1 114 119Morphological differentiation of bone marrow stromal cells intoneuron-like cells after co-culture with hippocampal slice

Abouelfetouh A, Kondoh T, Ehara K, Kohmura E

2004 54 Eur J Neurosci 2004 00 20 6 1577 1586Deletion of the CCK2 receptor gene reduces mechanical sensitivityand abolishes the development of hyperalgesia in mononeuropathic

Kurrikoff K, Koks S, Matsui T, Bourin M, Arend A, Aunapuu M,Vasar E

2004 55

Eur J Pharmacol 2004 00 502 3 243 252Unique roles of G protein-coupled histamine H2 and gastrin receptorsin growth and differentiation of gastric mucosa

Fukushima Y, Matsui T, Saitoh T, Ichinose M, Tateishi K, ShindoT, Fujishiro M, Sakoda H, Shojima N, Kushiyama A, Fukuda S,Anai M, Ono H, Oka M, Shimizu Y, Kurihara H, Nagai R, IshikawaT, Asano T, Omata M

2004 56 Int J Urol 2004 00 11 8 647 652Antitumor effect of simultaneous transfer of interleukin-12 andinterleukin-18 genes and its mechanism in a mouse bladder cancer

Hikosaka S, Hara I, Miyake H, Hara S, Kamidono S

2004 57 Surgery 2004 00 136 3 693 699Internal biliary drainage improves decreased number of gut mucosal Tlymphocytes and MAdCAM-1 expression in jaundiced rats

Sano T, Ajiki T, Takeyama Y, Kuroda Y

2004 58J Urol 2004 00 172 4 Pt 1 1485 1489

Synergistic inhibition of tumor growth and metastasis by combinedtreatment with TNP-470 and gemcitabine in a human bladder cancerKoTCC-1 model

Muramaki M, Miyake H, Hara I, Kawabata G, Kamidono S

2004 59 J Nucl Med 2004 00 45 7 1245 1250(18)F-FDG accumulation in atherosclerotic plaques:immunohistochemical and PET imaging study

Ogawa M, Ishino S, Mukai T, Asano D, Teramoto N, Watabe H,Kudomi N, Shiomi M, Magata Y, Iida H, Saji H

2004 60Kobe J Med Sci 2004 00 50 3 59 67

Imbalance of Matrix Metalloproteinase-9 and Tissue Inhibitor of MatrixMetalloproteinase-1 is Associated with Pulmonary Emphysema inKlotho Mice

Funada Y, Nishimura Y, Yokoyama M

2004 61 Cancer Res 2004 00 64 24 8808 8810Crucial role of phospholipase Cepsilon in chemical carcinogen-inducedskin tumor development

Bai YF, Edamatsu H, Maeda S, Saito H, Suzuki N, Satoh T,Kataoka T

2004 62 J Biol Chem 2004 00 279 38 39951 39957 Role of MAPK phosphatase-1 (MKP-1) in adipocyte differentiation Sakaue H, Ogawa W, Nakamura T, Mori T, Nakamura K, Kasuga M

2004 63Clin Cancer Res 2004 00 10 21 7318 7328

High expression of PRL-3 promotes cancer cell motility and livermetastasis in human colorectal cancer: a predictive molecular markerof metachronous liver and lung metastases

Kato H, Semba S, Miskad UA, Seo Y, Kasuga M, Yokozaki H

2004 64 J Biol Chem 2004 00 279 52 54032 54038Endothelial lipase modulates monocyte adhesion to the vessel wall. Apotential role in inflammation

Kojima Y, Hirata K, Ishida T, Shimokawa Y, Inoue N, KawashimaS, Quertermous T, Yokoyama M

2004 65 Horm Metab Res 2004 00 36 10 674 678Testosterone increases osteoprotegerin mRNA expression in mouseosteoblast cells

Chen Q, Kaji H, Kanatani M, Sugimoto T, Chihara K

2004 66 Connect Tissue Res 2004 00 45 3 164 173 Expression of transcription factor Sox9 in rat L6 myoblastic cellsMatsushita T, Matsui N, Fujioka H, Kubo S, Kuroda R, KurosakaM, Yoshiya S

2004 67Exp Anim 2004 00 53 4 339 346

Progression of coronary atherosclerosis relates to the onset ofmyocardial infarction in an animal model of spontaneous myocardialinfarction (WHHLMI rabbits)

Ito T, Yamada S, Shiomi M

2004 68 Acta Anaesthesiol Scand 2004 00 48 8 1066 1067Lidocaine attenuates streptozotocin-induced diaphragmaticdysfunction in rats

Kodama SI, Mikawa K, Nishina K, Obara H

2004 69J Gastroenterol 2004 00 39 4 319 323

Enhanced gastric emptying of a liquid gastric load in mice lackingcholecystokinin-B receptor: a study of CCK-A,B, and AB receptorgene knockout mice

Miyasaka K, Ohta M, Kanai S, Yoshida Y, Sato N, Nagata A,Matsui T, Noda T, Jimi A, Takiguchi S, Takata Y, Kawanami T,Funakoshi A

2004 70 J Pharmacol Sci 2004 00 96 2 115 123Inhibition mechanism of Gosha-jinki-gan on the micturition reflex inrats

Gotoh A, Goto K, Sengoku A, Shirakawa T, Akao Y, Fujisawa M,Okada H, Arakawa S, Kamidono S

2004 71 Endothelium 2004 00 11 2 99 107The two faces of endothelial nitric oxide synthase in thepathophysiology of atherosclerosis

Kawashima S

2004 72 Coron Artery Dis 2004 00 15 7 419 426Novel insights into coronary lumen preservation during progression ofcoronary atherosclerosis in coronary atherosclerosis-prone rabbits

Shiomi M, Ito T, Hasegawa M, Yoshida K, Gould KL

2004 73 Behav Brain Res 2004 00 155 1 1 11Targeted mutation of CCK(2) receptor gene antagonises behaviouralchanges induced by social isolation in female, but not in male mice

Abramov U, Raud S, Koks S, Innos J, Kurrikoff K, Matsui T,Vasar E

2004 74 Ophthalmology 2004 00 111 12 2278 2283Optical coherence tomography detects characteristic retinal nervefiber layer thickness corresponding to band atrophy of the optic discs

Kanamori A, Nakamura M, Matsui N, Nagai A, Nakanishi Y,Kusuhara S, Yamada Y, Negi A

2004 75 J Hepatobiliary Pancreat Surg 2004 00 11 3 176 180Short-term effects of external and internal biliary drainage on liverand cellular immunity in experimental obstructive jaundice

Mizuguchi K, Ajiki T, Onoyama H, Tomita M, Kuroda Y

2004 76 Microbiol Immunol 2004 00 48 4 289 295Introduction of 65 kDa antigen of Mycobacterium tuberculosis tocancer cells enhances anti-tumor effect of BCG therapy

Hara I, Sato N, Miyake H, Muramaki M, Hikosaka S, Kamidono S

2004 77 Nepal Med Coll J 2004 00 6 1 7 12Epidemiological survey of intestinal parasitic infections of diarrhoealpatients in Nepal and Lao PDR

Takemasa K, Kimura K, May SI, Rai SK, Ohyama F, Wu Z, KimuraD, Uga S

2004 78日本整形外科学会雑誌 2004 12 78

12号

934 938椎間板変性の分子メカニズムから治療へ　変性椎間板に対する遺伝子治療の問題点と新たな展開　超音波コントラスト法による椎間板へのin vivo遺伝子導入法の確立

西田康太郎, 土井田稔, 宮本裕史, 高田徹, 角谷賢一朗, 黒坂昌弘

2004 79 日本臨床 2004 11 6211号

1984 1988【急性膵炎　重症化機序とその対策】　膵炎実験モデル動物を利用した急性膵炎重症化機序解明の方法論

上田隆, 竹山宜典, 黒田嘉和

2004 80 Diabetes Frontier 2004 10 155

号649 653

【1型糖尿病　予防と治療に関する総合的アプローチ】　モデル動物(NODマウス,BBラット)における1型糖尿病の予防

森山啓明, 永田正男, 横野浩一

2004 81日本臨床 2004 9 62

増刊９

474 477【臨床分子内分泌学　心血管内分泌代謝系】　基礎研究の進展　NO関連遺伝子改変動物　eNOS過剰発現マウス

川嶋成乃亮

2004 82 今日の移植 2004 9 175

号660 666

【心停止ドナーからの臓器移植でクリアーすべき問題点】　阻血障害膵からの膵島移植に対する二層法の効用

谷岡康喜, 酒井哲也, 黒田嘉和

2004 83 日本臨床 2004 9 62増刊

493 495【臨床分子内分泌学　心血管内分泌代謝系】　薬理作用と生理作用LDL酸化抑制作用

藤岡由夫, 谷口隆弘, 石川雄一, 横山光宏

2004 84 細胞工学 2004 6 23 6 642 646 WntとRor2によるPCP経路の制御 依田　成玄，可児　修一，南　康博

2004 85 行動科学 2004 6 42 1 11 24 胎児からのメッセージ　―神経行動奇形学からのアプローチ― 杉岡　幸三,薛　富義,寺島　俊雄

2004 86

医学のあゆみ 2004 5

別冊

NOと病態

109 112 内分泌系　1型糖尿病とNO　NOによる膵β細胞破壊 永田正男

2004 87 医学のあゆみ 2004 5 別冊 25 28 循環器系　動脈硬化の病態におけるeNOS/NO系機能障害の役割 川嶋成乃亮

2004 88 日本鼻科学会会誌 2004 4 431

号92 94 においと受容機構　嗅覚器の構造と中枢伝達経路

市村恵一, 太田康, 丹生健一, 石川敏夫, 高野澤美奈子, 牧野伸子, 安井理絵, 近藤健二, 松本千織

2004 89 生理心理学と精神生理学 2004 4 21 1 19 30海馬の発生学的形態異常を伴う実験的小頭（脳）症ラットの空間認知障害

杉岡　幸三,薛　富義,寺島　俊雄

2004 90 日本循環器病予防学会誌 2004 4 39 2 93 93 循環器病と酸化ストレス　動脈硬化と酸化ストレス 川嶋成乃亮

2004 91 現代医療 2004 3 363

号651 655

【関節リウマチ　基礎と臨床】　関節リウマチをめぐる基礎的研究　関節リウマチの遺伝素因探索　血管新生因子の関節リウマチ病態形成機

駒井浩一郎, 中務美紀子, 酒井千菜, 塩澤俊一

2004 92 臨床免疫 2004 3 413

号291 296

【関節炎をめぐる新知見】　分子遺伝学アプローチによる関節リウマチ(RA)遺伝素因探索　血管新生因子Angiopoietin-1のRA病態形成機構

駒井浩一郎, 中務美紀子, 酒井千菜, 田中君枝, 松山浩子, 積山賢, 柱本照, 三浦靖史, 塩沢俊一

2004 93 脳循環代謝 2004 3 16 1 15 16マニトール頸動脈内注入前後の脳循環動態　CBF及び微小脳血管撮影よりみた検討（会議録）

森下暁二，近藤威，中島誠爾，山下晴央，甲村英二，櫻井孝

2004 94 Angiology Frontier 2004 3 31

号74 77 循環障害とセロトニン　循環障害におけるセロトニンの役割 平田健一

2004 95 病理と臨床 2004 3 223

号285 289 悪性腫瘍の骨破壊病変における遺伝子発現 北澤理子, 北澤荘平

2004 96 血管医学 2004 2 51

号11 16

【血管の先進映像医学】　放射光微小血管造影装置による再生血管の可視化

山下智也, 高谷具史, 川嶋成乃亮, 梅谷啓二, 篠原正和, 横山光宏

2003 1 J Neurosci Res 2003 12 74 6 852 857Two types of VIP neuronal components in rat suprachiasmaticnucleus

Kawamoto K, Nagano M, Kanda F, Chihara K, Shigeyoshi Y,Okamura H

2003 2 J Asthma 2003 12 40 8 935 944 Airway remodeling of murine chronic antigen exposure modelTsuchiya T, Nishimura Y, Nishiuma T, Kotani Y, Funada Y,Yoshimura S, Yokoyama M

2003 3 J Pediatr Surg 2003 12 38 12 1707 1711Transplantation of the cryopreserved tracheal allograft in growingrabbits

Tanaka H, Maeda K, Okita Y

2003 4 Atherosclerosis 2003 12 171 2 193 200Chylomicron remnants induce monocyte chemoattractant protein-1expression via p38 MAPK activation in vascular smooth muscle cells

Domoto K, Taniguchi T, Takaishi H, Takahashi T, Fujioka Y,Takahashi A, Ishikawa Y, Yokoyama M

2003 5 Anesth Analg 2003 12 97 6 1751 1755ONO-1714, a nitric oxide synthase inhibitor, attenuates endotoxin-induced acute lung injury in rabbits

Mikawa K, Nishina K, Takao Y, Obara H

2003 6 Histochem Cell Biol 2003 12 120 6 493 503 Heparanase mRNA expression during fracture repair in miceSaijo M, Kitazawa R, Nakajima M, Kurosaka M, Maeda S,Kitazawa S

2003 7 Urol Res 2003 12 31 6 387 396Radiation induces p53-dependent cell apoptosis in bladder cancercells with wild-type- p53 but not in p53-mutated bladder cancer cells

Hinata N, Shirakawa T, Zhang Z, Matsumoto A, Fujisawa M,Okada H, Kamidono S, Gotoh A

2003 8 Hepatogastroenterology 2003 11 50 54 1854 1856Brain death-induced expression of ICAM-1 and VCAM-1 on rathepatocytes

Toyama H, Takada M, Suzuki Y, Kuroda Y

2003 9Clin Cancer Res 2003 11 9 14 5152 5160

Introduction of midkine gene into human bladder cancer cellsenhances their malignant phenotype but increases their sensitivity toantiangiogenic therapy

Muramaki M, Miyake H, Hara I, Kamidono S

2003 10 Arthroscopy 2003 11 19 9 969 973Analysis of the thickness and curvature of articular cartilage of thefemoral condyle

Terukina M, Fujioka H, Yoshiya S, Kurosaka M, Makino T, MatsuiN, Tanaka J

2003 11 Science 2003 11 302 5649 1408 1412 Synchronization of cellular clocks in the suprachiasmatic nucleusYamaguchi S, Isejima H, Matsuo T, Okura R, Yagita K, KobayashiM, Okamura H

2003 12 Biochem Biophys Res Commun 2003 10 310 1 228 235Decreased mAKAP, ryanodine receptor, and SERCA2a geneexpression in mdx hearts

Rohman MS, Emoto N, Takeshima Y, Yokoyama M, Matsuo M

2003 13 Neuroreport 2003 10 14 14 1857 1860Responses to noxious stimuli in mice lacking alpha(1d)-adrenergicreceptors

Harasawa I, Honda K, Tanoue A, Shinoura H, Ishida Y, OkamuraH, Murao N, Tsujimoto G, Higa K, Kamiya HO, Takano Y

2003 14 Science 2003 10 302 5643 255 259Control mechanism of the circadian clock for timing of cell division invivo

Matsuo T, Yamaguchi S, Mitsui S, Emi A, Shimoda F, Okamura H

2003 15 J Biol Chem 2003 10 278 40 38870 38874Requirement for 3-phosphoinositide-kependent dinase-1 (PDK-1) ininsulin-induced glucose uptake in immortalized brown adipocytes

Sakaue H, Nishizawa A, Ogawa W, Teshigawara K, Mori T,Takashima Y, Noda T, Kasuga M

2003 16 J Gene Med 2003 10 5 10 860 867Combination with CD/5-FC gene therapy enhances killing of humanbladder-cancer cells by radiation

Zhang Z, Shirakawa T, Hinata N, Matsumoto A, Fujisawa M,Okada H, Kamidono S, Matsuo M, Gotoh A

2003 17

Commentary to the InternationalAtherosclerosis Society IASWebsite(http://www.athero.org/comm-index.asp)

2003 09Relation of vulnerable plaque to development of myocardial infarction/acute coronary syndromes - Lessons from an animal model ofspontaneous myocardial infarction

Shiomi M, Fan J, Kawashima S

2003 18 Vaccine 2003 09 21 25-26 3713 3720Evidence for antigen production in muscles by dengue and Japaneseencephalitis DNA vaccines and a relation to their immunogenicity in

Konishi E, Terazawa A, Fujii A

2003 19 J Surg Res 2003 09 114 1 6 14Pancreatic duct obstruction itself induces expression of alpha smoothmuscle actin in pancreatic stellate cells

Kishi S, Takeyama Y, Ueda T, Yasuda T, Shinzeki M, Kuroda Y,Yokozaki H

2003 20Vaccine 2003 09 21 25-26 3675 3683

Comparison of protective efficacies of plasmid DNAs encodingJapanese encephalitis virus proteins that induce neutralizing antibodyor cytotoxic T lymphocytes in mice

Konishi E, Ajiro N, Nukuzuma C, Mason PW, Kurane I

2003 21Surgery 2003 09 134 3 437 445

Pancreas preservation by the 2-layer cold storage method beforeislet isolation protects isolated islets against apoptosis through themitochondrial pathway

Matsuda T, Suzuki Y, Tanioka Y, Toyama H, Kakinoki K, HiraokaK, Fujino Y, Kuroda Y

2003 22Clin Exp Immunol 2003 09 133 3 318 325

Critical roles of CD30/CD30L interactions in murine autoimmunediabetes

Chakrabarｔy S, Nagata M, Yasuda H, Wen L, Nakayama M,Chowdhury SA, Yamada K, Jin Z, Kotani R, Moriyama H,Shimozato O, Yagita H, Yokono K

2003 23J Clin Invest 2003 09 112 6 935 944

PKClambda in liver mediates insulin-induced SREBP-1c expressionand determines both hepatic lipid content and overall insulinsensitivity

Matsumoto M, Ogawa W, Akimoto K, Inoue H, Miyake K,Furukawa K, Hayashi Y, Iguchi H, Matsuki Y, Hiramatsu R,Shimano H, Yamada N, Ohno S, Kasuga M, Noda T

2003 24 Transplantation 2003 09 76 5 777 780Successful 24-hour preservation of ischemically damaged caninesmall intestine by the cavitary two-layer method

Fujino Y, Kakinoki K, Suzuki Y, Li S, Tanaka T, Tanioka Y, SakaiT, Ku Y, Kuroda Y

2003 25 Arch Histol Cytol 2003 08 66 3 209 220Retrograde labeling of mouse spinal descending tracts by arecombinant adenovirus

Tsukamoto Y, Yamamoto T, Okado H, Nibu K, Terashima T

2003 26Arterioscler Thromb Vasc Biol 2003 08 23 8 1398 １404

Interaction of oxidative stress and inflammatory response in coronaryplaque instability: important role of C-reactive protein

Kobayashi S, Inoue N, Ohashi Y, Terashima M, Matsui K, Mori T,Fujita H, Awano K, Kobayashi K, Azumi H, Ejiri J, Hirata K,Kawashima S, Hayashi Y, Yokozaki H, Itoh H, Yokoyama M

2003 27 Hypertension 2003 08 42 2 189 194Alterations of circadian expressions of clock genes in Dahl salt-sensitive rats fed a high-salt diet

Mohri T, Emoto N, Nonaka H, Fukuya H, Yagita K, Okamura H,Yokoyama M

2003 28 Prostate 2003 08 56 3 231 238 Establishment of a prostatic small-cell carcinoma cell line (SO-MI)Okada H, Shirakawa T, Miyake H, Gotoh A, Fujisawa M, ArakawaS, Kamidono S

2003 29 J Comp Neurol 2003 08 463 3 303 315Missplicing resulting from a short deletion in the reelin gene causesreeler-like neuronal disorders in the mutant shaking rat Kawasaki

Kikkawa S, Yamamoto T, Misaki K, Ikeda Y, Okado H, Ogawa M,Woodhams PL, Terashima T

2003 30Neurosci Res 2003 08 46 4 443 452

Brain expression of apurinic/apyrimidinic endonuclease (APE/Ref-1)multifunctional DNA repair enzyme gene in the mouse with specialreference to the suprachiasmatic nucleus

Kimura H, Dong X, Yagita K, Okamura H

2003 31 Proc Natl Acad Sci U S A 2003 08 100 16 9584 9589Bimodal circadian secretion of melatonin from the pineal gland in aliving CBA mouse

Nakahara D, Nakamura M, Iigo M, Okamura H

2003 32 Surg Endosc 2003 08 17 8 1237 1240Comparison of intestinal transit recovery between laparoscopic andopen surgery using a rat model

Takada M, Fukumoto S, Ichihara T, Ku Y, Kuroda Y

2003 33 BJU Int 2003 08 92 3 314 318The growth inhibitory effect of p21 adenovirus on androgen-dependent and -independent human prostate cancer cells

Gotoh A, Shirakawa T, Wada Y, Fujisawa M, Okada H, KamidonoS, Hamada K

2003 34J Biol Chem 2003 08 278 31 29057 29064

The receptor tyrosine kinase Ror2 associates with the melanoma-associated antigen (MAGE) family protein Dlxin-1 and regulates itsintracellular distribution

Matsuda T, Suzuki H, Oishi I, Kani S, Kuroda Y, Komori T, SasakiA, Watanabe K, Minami Y

2003 35 Br J Surg 2003 08 90 8 1015 1020Protection against experimental small intestinal ischaemia-reperfusioninjury with oxygenated perfluorochemical

Fujino Y, Suzuki Y, Kakinoki K, Tanioka Y, Ku Y, Kuroda Y

2003 36 Nature 2003 08 424 6951 961 965 Feedback regulation of MAPK signalling by an RNA-binding protein Sugiura R, Kita A, Shimizu Y, Shuntoh H, Sio SO, Kuno T

2003 37Genes Cells 2003 07 8 7 645 654

The receptor tyrosine kinase Ror2 is involved in non-canonicalWnt5a/JNK signalling pathway

Oishi I, Suzuki H, Onishi N, Takada R, Kani S, Ohkawara B,Koshida I, Suzuki K, Yamada G, Schwabe GC, Mundlos S,Shibuya H, Takada S, Minami Y

2003 38 Pharmacogenomics 2003 07 4 4 397 410Pharmacogenetics of MDR1 and its impact on the pharmacokineticsand pharmacodynamics of drugs

Sakaeda T, Nakamura T, Okumura K

2003 39 Arterioscler Thromb Vasc Biol 2003 07 23 7 1239 1244Development of an animal model for spontaneous myocardialinfarction (WHHLMI rabbit)

Shiomi M, Ito T, Yamada S, Kawashima S, Fan J

2003 40 Neurosci Res 2003 07 46 3 333 337Effects of lactate/pyruvate on synaptic plasticity in the hippocampaldentate gyrus

Yang B, Sakurai T, Takata T, Yokono K

2003 41 Oncol Rep 2003 07 10 4 939 943Lymphagenesis correlates with expression of vascular endothelialgrowth factor-C in colorectal cancer

Ohno M, Nakamura T, Kunimoto Y, Nishimura K, Chung-Kang C,Kuroda Y

2003 42 Hepatogastroenterology 2003 07 50 52 902 905Apoptosis in Helicobacter pylori gastritis and residual gastritis afterdistal gastrectomy

Tomonaga K, Takada M, Ichihara T, Kuroda Y

2003 43 J Cardiovasc Pharmacol 2003 07 42 1 136 141The effects of phosphoramidon on the expression of humanendothelin-converting enzyme-1 (ECE-1) isoforms

Isaka D, Emoto N, Raharjo SB, Yokoyama M, Matsuo M

2003 44 Kidney Int 2003 07 64 1 92 101Blockade of TGF-beta action ameliorates renal dysfunction andhistologic progression in anti-GBM nephritis

Zhou A, Ueno H, Shimomura M, Tanaka R, Shirakawa T,Nakamura H, Matsuo M, Iijima K

2003 45 Anesth Analg 2003 06 96 6 1674 1678The effects of enflurane, isoflurane, and intravenous anesthetics onrat diaphragmatic function and fatigability

Nishina K, Mikawa K, Kodama S, Kagawa T, Uesugi T, Obara H

2003 46 J Comp Neurol 2003 06 461 1 61 75Ectopic corticospinal tract and corticothalamic tract neurons in thecerebral cortex of yotari and reeler mice

Yamamoto T, Sakakibara S, Mikoshiba K, Terashima T

2003 47 Transplant Proc 2003 06 35 4 1503 1505Characterization of islet-infiltrating immunocytes after pancreaspreservation by two-layer (UW/perfluorochemical) cold storage

Toyama H, Takada M, Tanaka T, Suzuki Y, Kuroda Y

2003 48 Ann Surg Oncol 2003 06 10 5 546 550An experimental study on the pharmacokinetics of 5-Fluorouracilregional chemotherapy for pancreatic cancer

Mitsutsuji M, Suzuki Y, Iwanaga Y, Fujino Y, Tanioka Y, KamigakiT, Ku Y, Kuroda Y

2003 49 Proc Natl Acad Sci U S A 2003 05 100 11 6795 6800 Adrenergic regulation of clock gene expression in mouse liverTerazono H, Mutoh T, Yamaguchi S, Kobayashi M, Akiyama M,Udo R, Ohdo S, Okamura H, Shibata S

2003 50Vaccine 2003 05 21 17-18 1826 1832

Simultaneous immunization with DNA and protein vaccines againstJapanese encephalitis or dengue synergistically increases their ownabilities to induce neutralizing antibody in mice

Konishi E, Terazawa A, Imoto J

2003 51 J Biol Chem 2003 04 278 17 14657 14668c-MIR, a human E3 ubiquitin ligase, is a functional homolog ofherpesvirus proteins MIR1 and MIR2 and has similar activity

Goto E, Ishido S, Sato Y, Ohgimoto S, Ohgimoto K, Nagano-FujiiM, Hotta H

2003 52 Eur J Neurosci 2003 04 17 8 1571 1580Neuronal lineage-specific induction of phospholipase Cepsilonexpression in the developing mouse brain

Wu D, Tadano M, Edamatsu H, Masago-Toda M, Yamawaki-Kataoka Y, Terashima T, Mizoguchi A, Minami Y, Satoh T,

2003 53

12th International RheumatologySymposium

2003 04Molecular Genetics and Biochemistry of the Rheumatoid arthritisDisease Genes, Death Receptor 3 (DR3), Angiopoietin-1 (Ang-1) andDbl containing Nucleotide Polymorphism

Shiozawa S, Komai K, Nakatsukasa M, Osawa K, Sato M,Okayama R, Murao H, Nakashima T, Arakawa A, Hirano K, SakaiC, Kitamura H, Takami N, Shiotsuki T, Matsuyama H,

2003 54 Hypertension 2003 04 41 4 956 962Ral GDP dissociation stimulator and Ral GTPase are involved inmyocardial hypertrophy

Kawai M, Kawashima S, Sakoda T, Toh R, Kikuchi A, Yamauchi-Takihara K, Kunisada K, Yokoyama M

2003 55 Life Sci 2003 04 72 22 2517 2524The role of circulating ghrelin in growth hormone (GH) secretion infreely moving male rats

Okimura Y, Ukai K, Hosoda H, Murata M, Iguchi G, Iida K, Kaji H,Kojima M, Kangawa K, Chihara K

2003 56 Kidney Int 2003 03 63 3 947 957Methylglyoxal induces apoptosis through activation of p38 mitogen-activated protein kinase in rat mesangial cells

Liu BF, Miyata S, Hirota Y, Higo S, Miyazaki H, Fukunaga M,Hamada Y, Ueyama S, Muramoto O, Uriuhara A, Kasuga M

2003 57 Jpn J Ophthalmol 2003 03 47 2 166 172Analysis of cytokine mRNAs in murine herpes simplex virus type 1retinitis

Saitoh-Ishibashi K, Ishibashi K, Azumi A, Negi A

2003 58 Psychopharmacology (Berl) 2003 03 166 2 168 175Altered pain sensitivity and morphine-induced anti-nociception inmice lacking CCK2 receptors

Veraksits A, Runkorg K, Kurrikoff K, Raud S, Abramov U, MatsuiT, Bourin M, Koks S, Vasar E

2003 59 J Diabetes Complications 2003 03 17 2 105 107 Leptin treatment ameliorates anxiety in ob/ob obese mice Asakawa A, Inui A, Inui T, Katsuura G, Fujino MA, Kasuga M

2003 60 Neuropeptides 2003 02 37 1 25 29CCK2 receptor-deficient mice have increased sensitivity of dopamineD2 receptors

Koks S, Abramov U, Veraksits A, Bourin M, Matsui T, Vasar E

2003 61 J Physiol 2003 02 547 Pt 1 317 332Melatonin modulates the light-induced sympathoexcitation and vagalsuppression with participation of the suprachiasmatic nucleus in mice

Mutoh T, Shibata S, Korf HW, Okamura H

2003 62 World J Surg 2003 02 27 2 145 148Expression of cyclooxygenases in Helicobacter pylori gastritis andresidual gastritis after distal gastrectomy

Fukumoto S, Ichihara T, Takada M, Kuroda Y

2003 63 Kobe J Med Sci 2003 02 49 1 17 24Intraperitoneal administration of oxygenated perfluorochemical inhibitsbacterial translocation associated with severe acute pancreatitis

Shinzeki M, Takeyama Y, Ueda T, Yasuda T, Kishi S, Kuroda Y

2003 64 Genes Cells 2003 02 8 2 81 93Isolation and expression of a novel mitochondrial septin that interactswith CRMP/CRAM in the developing neurones

Takahashi S, Inatome R, Yamamura H, Yanagi S

2003 65FASEB J 2003 02 17 2 295 297

Apolipoprotein E and Reelin ligands modulate tau phosphorylationthrough an apolipoprotein E receptor/disabled-1/glycogen synthasekinase-3beta cascade

Ohkubo N, Lee YD, Morishima A, Terashima T, Kikkawa S,Tohyama M, Sakanaka M, Tanaka J, Maeda N, Vitek MP, MitsudaN

2003 66 J Biol Chem 2003 02 278 6 3514 3520Molecular identification and characterization of a novel nuclearprotein whose expression is up-regulated in insulin-resistant animals

Ikeda K, Emoto N, Matsuo M, Yokoyama M

2003 67 Pancreas 2003 01 26 1 95 97Nonocclusive visceral ischemia associated with severe acutepancreatitis

Yasuda T, Takeyama Y, Ueda T, Hori Y, Nishikawa J, Kuroda Y

2003 68 Stroke 2003 01 34 1 157 163HMG-CoA reductase inhibitor has protective effects against strokeevents in stroke-prone spontaneously hypertensive rats

Kawashima S, Yamashita T, Miwa Y, Ozaki M, Namiki M, Hirase T,Inoue N, Hirata K, Yokoyama M

2003 69 J Diabetes Complications 2003 01 17 1 27 28 Ob/ob mice as a model of delayed gastric emptyingAsakawa A, Inui A, Ueno N, Makino S, Uemoto M, Fujino MA,Kasuga M

2003 70 Neurotrauma Res 2003 00 15 1 37 40Morphological transdifferentiation of bone marrow stromal cells toneuronal cells

Abouelfetouh A, Kondoh T, Mizobe T, Kidoguchi K, Tamaki M,Ehara k, Kohmura E

2003 71 Neuroscience 2003 00 116 4 1141 1147The activity-regulated cytoskeleton-associated (Arc) gene is a newlight-inducible early gene in the mouse suprachiasmatic nucleus

Nishimura M, Yamagata K, Sugiura H, Okamura H

2003 72 Cell Transplant 2003 00 12 1 27 32Activation of macrophage-associated molecules after brain death inislets

Toyama H, Takada M, Suzuki Y, Kuroda Y

2003 73 Viral Immunol 2003 00 16 183 189Enhancing effect of vaxfectin on the ability of a Japanese encephalitisDNA vaccine to induce neutralizing antibody in mice

Nukuzuma C, Ajiro N, Wheeler CJ, Konishi E

2003 74 Kobe J Med Sci 2003 00 49 5 117 122 Expression of mPOU Protein in the Human Pituitary AdenomasSakagami Y, Okimura Y, Kondoh T, Iguchi G, Fumoto M, Kuno T,Chihara K, Kohmura E

2003 75 Acta Neurochir Suppl 2003 00 86 559 563Quantitative analysis of hyperosmotic and hypothermic blood-brainbarrier opening

Ikeda M, Nagashima T, Bhattacharjee AK, Kondoh T, Kohmura E,Tamaki N

2003 76 Kobe J Med Sci 2003 00 49 3-4 93 98Alpha E- and alpha N-catenin expression in dorsal root ganglia andspinal cord

Shibuya Y, Murata M, Munemoto S, Masago H, Takeuchi J, WadaK, Yokoo S, Umeda M, Komori T

2003 77 Drug Dev Res 2003 00 58 479 485Inhibition of the Nucleoside Transporter Inhibits Disease Progressionin the Rat Adjuvant-Induced Arthritis Model

Kosaka H, Koshiba M, Nakazawa T, Tsuji G, Saegusa J,Kanagawa S, Saura R, Kurosaka M, Yoshino S, Kumagai S

2003 78 Methods Mol Biol 2003 00 233 93 103 Fluorescence imaging of protein kinase C translocation in living cells Saito N

2003 79 Kobe J Med Sci 2003 00 49 1-2 25 37PI 3-kinase-Akt-p70 S6 kinase in hypertrophic responses to leukemiainhibitory factor in cardiac myocytes

Hiraoka E, Kawashima S, Takahashi T, Rikitake Y, Hirase T,Yokoyama M

2003 80 Molecular Medicine 2003 12 40臨増

336 342【免疫2004】　病気と免疫　マイクロサテライトマーカーによる家系解析関節リウマチの疾患遺伝子について

塩沢俊一, 駒井浩一郎, 大澤佳代, 田中泰史, 塩沢和子, 三浦靖史, 柱本照

2003 81 Molecular Medicine 2003 12 40臨増

312 320【免疫2004】　病気と免疫　新たな免疫抑制性E3ユビキチンリガーゼファミリー

石戸聡, 後藤栄治, 松木洋平, 佐藤祐也, 堀田博

2003 82 日本内視鏡外科学会雑誌 2003 10 85

号409 414

【LigaSureTM　新しい血管シーリングシステム】　LigaSureTMによる腹腔鏡下膵臓切除術

市原隆夫, 安田貴志, 高田壮豊, 平岡邦彦, 福本聡, 大野伯和,黒田嘉和

2003 83 日本医師会雑誌 2003 10 1308

号S163 S163 【糖尿病診療マニュアル】　基礎から臨床のトピックス　膵島移植 酒井哲也, 黒田嘉和

2003 84 Diabetes Frontier 2003 10 145

号543 551 生体膵島移植 酒井哲也, 谷岡康喜, 黒田嘉和

2003 85 神緑会学術誌 2003 8 19 92 96ノックアウトマウスを用いたキナーゼ欠損型Ephファミリー受容体「EphB6」の機能解析

下山学, 松井利充

2003 86 骨・関節・靱帯 2003 8 168

号804 809 【必見　腰痛学】　病態　椎間板の特殊性と遺伝子治療 西田康太郎, 土井田稔, 高田徹, 宮本裕史, 黒坂昌弘

2003 87 頭頸部自律神経 2003 8 18 18 20 老化促進モデルマウスSAM-P1の嗅上皮 土井清司, 丹生健一

2003 88 消化器科 2003 7 371

号14 19

【Bacterial Translocationの基礎と臨床】　ラット重症急性膵炎モデルにおけるbacterial translocationの機序

安田武生, 竹山宜典, 上田隆, 新関亮, 岸真示, 黒田嘉和

2003 89 今日の移植 2003 7 164

号331 337 ヒト膵島分離法の現状と将来の展望 谷岡康喜, 酒井哲也, 藤野泰宏, 鈴木康之, 黒田嘉和

2003 90 日本老年医学会雑誌 2003 7 404

号344 347

老化とホルモン　老化における脳の乳酸/ピルビン酸代謝とシナプス機能

櫻井孝, 楊波, 横野浩一

2003 91 臨床免疫 2003 6 396

号691 697 【炎症とその関与分子の解析】　アデノシンの抗炎症作用 小柴賢洋, 熊谷俊一

2003 92 消化器科 2003 5 365

号497 502 【慢性膵炎の発症と進展】　膵管閉塞機転と膵星細胞活性化

岸真示, 竹山宜典, 上田隆, 五島正裕, 安田武生, 新関亮, 松村直樹, 黒田嘉和, 横崎宏

2003 93 細胞 2003 5 355

号183 186

【アトピー性皮膚炎に迫る】　新しいアトピー性皮膚炎モデル:DS-Nhマウス

堀川達弥, 疋田一郎, 吉岡健

2003 94 日本腹部救急医学会雑誌 2003 3 233

号485 489

【bacterial translocationの診断と治療】　重症急性膵炎とbacterialtranslocation

安田武生, 竹山宜典, 上田隆, 新関亮, 岸真示, 黒田嘉和

2003 95 医学のあゆみ 2003 3 2049

号675 678 【NOと病態】　1型糖尿病とNO　NOによる膵β細胞破壊 永田正男

2003 96 日本消化器病学会雑誌 2003 3 100 3 298 305食欲・体重調節の分子機構ー特に、体脂肪量調節ループの重要性と病態における異常ー

乾明夫

2003 97 神戸大学医学部紀要 2003 3 633

～55 62

血管平滑筋細胞における成長ホルモン投与による遺伝子発現の変化differential display法を用いた検討

吉岡嗣朗, 千原和夫

2003 98 日本臨床 2003 2 61 2 623 628【新世紀の感染症学　ゲノム・グローバル時代の感染症アップデート】グローバル時代の感染症学　原虫感染症　バベシア症(解説/特集)

斎藤あつ子，AnchaleeDantrakool，河合敦子，矢野泰弘，高田伸弘

2003 99 Clinical Neuroscience 2003 2 212

号206 208

【神経疾患と分子病態モデルをめぐるトピックス】　モデル動物と脳血管障害因子　脳虚血障害における一酸化窒素と活性酸素の役割

山下智也, 横山光宏

2003 100 Clinical Neuroscience 2003 2 21 2 168 170 Shaking Rat Kawasaki における運動失調とその解剖学的基盤 寺島俊雄

2003 101 オベリスク 2003 0 8 2 8 10 動物実験に関する説明責任－動物実験に関する法規制と情報公開－ 塩見 雅志，伊藤 隆

2003 102 実験動物ニュース 2003 0 52 8 88 89動物実験に関する基本姿勢に基づいた情報開示請求への神戸大学医学部の対応－開示できる内容と開示できない内容－

塩見 雅志，伊藤 隆

2003 103 アニテックス 2003 0 15 4 11 14高脂血症・動脈硬化に関する研究におけるWHHLウサギを用いた研究の貢献

塩見 雅志，伊藤 隆

2003 104 実験医学 2003 0 21 1 30 35【ゲノム的アプローチによる多因子疾患の解明!】　疾患遺伝子からみた自己免疫疾患発症機構の研究

塩沢俊一，駒井浩一郎，中務美紀子

2003 105 生理心理学と精神生理学 2003 0 21 1 19 30海馬の発生学的形態異常を伴う実験的小頭（脳）症ラットの空間認知障害

杉岡幸三，薛富義，寺島俊雄

2003 106 生理心理 2003 0 21 1 19 30海馬の発生学的形態異常を伴う実験的小頭（脳）症ラットの空間認知障害

杉岡幸三，薛富義，寺島俊雄

2003 107 行動科学 2003 0 42 1 11 24 胎児からのメッセージ―神経行動奇形学からのアプローチ― 杉岡幸三，薛富義，寺島俊雄

2003 108 臨床精神医学 2003 0 32 1 89 96精神分裂病モデルの可能性としてのリーラーマウス：脳梁交連線維系を中心として

青木拓也，寺島俊雄，柿木達也，渡辺義文

2003 109 耳鼻咽喉・頭頸部外科 2003 0 75 7 433 441 頭頸部癌の遺伝子診断と遺伝子治療 丹生健一，田中博紀

2003 110 Surgery Frontier 2003 0 10 1 69 74 膵移植モデル作製法 鈴木康之，藤野泰宏，谷岡康喜，黒田嘉和

2002 1 Kobe J Med Sci 2002 12 48 5-6 161 166Cardiac myocytes are recruited by bone marrow-derived cells inintact murine heart

Satomi-Kobayashi S, Kawashima S, Sakoda T, Ueyama T, KawaiM, Toh R, Azumi H, Mizutani K, Hattori K, Yokoyama M

2002 2 Kobe J Med Sci 2002 12 48 6 167 175Tolerance mechanisms in murine autoimmune diabetes induced byanti-ICAM-1/LFA-1 mAb and anti-CD8 mAb

Chowdhury SA, Nagata M, Yamada K, Nakayama K, ChakrabartyS, Jin Z, Kotani R, Yokono K

2002 3J Hypertens 2002 12 20 12 2465 2473

A 3-hydroxy-3-methylglutaryl co-enzyme A reductase inhibitorreduces hypertensive nephrosclerosis in stroke-prone spontaneouslyhypertensive rats

Yamashita T, Kawashima S, Miwa Y, Ozaki M, Namiki M, Hirase T,Inoue N, Hirata K, Yokoyama M

2002 4 Kobe J Med Sci 2002 12 48 5-6 145 152Establishment of in vivo metastasis model of human adenoid cysticcarcinoma: detection of metastasis by PCR with human beta-globin

Komatsubara H, Umeda M, Oku N, Komori T

2002 5 Neurosci Lett 2002 12 335 2 115 118Anxiety-related behaviors in cholecystokinin-A, B, and AB receptorgene knockout mice in the plus-maze

Miyasaka K, Kobayashi S, Ohta M, Kanai S, Yoshida Y, Nagata A,Matsui T, Noda T, Takiguchi S, Takata Y, Kawanami T, Funakoshi

2002 6 Arterioscler Thromb Vasc Biol 2002 12 22 12 2049 2053Expression of G2A, a receptor for lysophosphatidylcholine, bymacrophages in murine, rabbit, and human atherosclerotic plaques

Rikitake Y, Hirata K, Yamashita T, Iwai K, Kobayashi S, Itoh H,Ozaki M, Ejiri J, Shiomi M, Inoue N, Kawashima S, Yokoyama M

2002 7 Neuroreport 2002 12 13 17 2217 2221MMP-9 and EBA immunoreactivity after papaverine mediated openingof the blood-brain barrier

Bhattacharjee AK, Kondoh T, Ikeda M, Kohmura E

2002 8 Diabetes Obes Metab 2002 11 4 6 399 401 Orexin reverses cholecystokinin-induced reduction in feeding Asakawa A, Inui A, Inui T, Katsuura G, Fujino MA, Kasuga M

2002 9 Int J Oral Maxillofac Implants 2002 11 17 6 846 853Endosseous implants in horizontal alveolar ridge distractionosteogenesis

Nosaka Y, Kitano S, Wada K, Komori T

2002 10 J Orthop Res 2002 11 20 6 1380 1386Mechanical stretching force promotes collagen synthesis by culturedcells from human ligamentum flavum via transforming growth factor-

Nakatani T, Marui T, Hitora T, Doita M, Nishida K, Kurosaka M

2002 11J Dermatol Sci 2002 11 30 2 142 153

Characterization of dermatitis arising spontaneously in DS-Nh micemaintained under conventional conditions: another possible model foratopic dermatitis

Hikita I, Yoshioka T, Mizoguchi T, Tsukahara K, Tsuru K, Nagai H,Hirasawa T, Tsuruta Y, Suzuki R, Ichihashi M, Horikawa T

2002 12 J Clin Invest 2002 11 110 10 1483 1491Hyperinsulinemia, glucose intolerance, and dyslipidemia induced byacute inhibition of phosphoinositide 3-kinase signaling in the liver

Miyake K, Ogawa W, Matsumoto M, Nakamura T, Sakaue H,Kasuga M

2002 13 Circ J 2002 11 66 11 1057 1059In vivo angiographic detection of vascular lesions in apolipoprotein E-knockout mice using a synchrotron radiation microangiography system

Yamashita T, Kawashima S, Ozaki M, Namiki M, Shinohara M,Inoue N, Hirata K, Umetani K, Yokoyama M

2002 14 Int J Mol Med 2002 10 10 4 523 525Effects of agouti-related protein, orexin and melanin-concentratinghormone on oxygen consumption in mice

Asakawa A, Inui A, Goto K, Yuzuriha H, Takimoto Y, Inui T,Katsuura G, Fujino MA, Meguid MM, Kasuga M

2002 15 J Pathol 2002 10 198 2 228 236 RANK ligand is a prerequisite for cancer-associated osteolytic lesions Kitazawa S, Kitazawa R

2002 16J Biol Chem 2002 10 277 42 39833 39839

Negative regulation of platelet clearance and of the macrophagephagocytic response by the transmembrane glycoprotein SHPS-1

Yamao T, Noguchi T, Takeuchi O, Nishiyama U, Morita H,Hagiwara T, Akahori H, Kato T, Inagaki K, Okazawa H, Hayashi Y,Matozaki T, Takeda K, Akira S, Kasuga M

2002 17 Exp Anim 2002 10 51 5 493 499Decreased arterial responses in WHHL rabbits, an animal model ofspontaneous hypercholesterolemia and atherosclerosis

Yamada S, Ito T, Adachi J, Ueno Y, Shiomi M

2002 18Biochem Biophys Res Commun 2002 10 298 1 87 94

Developmental expression of EphB6 in the thymus: lessons fromEphB6 knockout mice

Shimoyama M, Matsuoka H, Nagata A, Iwata N, Tamekane A,Okamura A, Gomyo H, Ito M, Jishage K, Kamada N, Suzuki H,Noda T, Matsui T

2002 19 Surgery 2002 09 132 3 424 430Effect of portal vein embolization on function of the nonembolizedlobes of the liver: Evaluation by first-pass hepatic lidocaine extraction

Tominaga M, Ku Y, Iwasaki T, Fukumoto T, Muramatsu S,Kusunoki N, Suzuki Y, Fujino Y, Kuroda Y

2002 20 Jpn J Ophthalmol 2002 09 46 5 488 495Effects of various eye drops on corneal wound healing after superficialkeratectomy in rabbits

Tani E, Katakami C, Negi A

2002 21Transpl Int 2002 09 15 8 425 430

Ultrastructural analyses of pancreatic grafts preserved by the two-layer cold-storage method and by simple cold storage in University ofWisconsin solution

Iwanaga Y, Suzuki Y, Okada Y, Mori H, Matsumoto I, Mitsutsuji M,Tanioka Y, Fujino Y, Tominaga M, Ku Y, Kuroda Y

2002 22 Circ J 2002 09 66 9 851 856Overexpression of endothelial nitric oxide synthase attenuatescardiac hypertrophy induced by chronic isoproterenol infusion

Ozaki M, Kawashima S, Yamashita T, Hirase T, Ohashi Y, InoueN, Hirata K, Yokoyama M

2002 23J Invest Dermatol 2002 09 119 3 541 548

Gene transfer of secreted-type modified interleukin-18 gene toB16F10 melanoma cells suppresses in vivo tumor growth throughinhibition of tumor vessel formation

Nagai H, Hara I, Horikawa T, Oka M, Kamidono S, Ichihashi M

2002 24 Hypertens Res 2002 09 25 5 787 795Decreased ornithine decarboxylase activity in the kidneys of Dahlsalt-sensitive rats

Hayashi T, Tsujino T, Iwata S, Nonaka H, Emoto N, Yano Y, OtaniS, Hayashi Y, Itoh H, Yokoyama M

2002 25Kobe J Med Sci 2002 08 48 3-4 97 104

The effect of the small and unstable autologous osteochondral grafton repairing the full-thickness large articular cartilage defect in arabbit model

Makino T, Fujioka H, Yoshiya S, Terukina M, Matsui N, KurosakaM

2002 26 J Clin Invest 2002 08 110 3 331 340Overexpression of endothelial nitric oxide synthase acceleratesatherosclerotic lesion formation in apoE-deficient mice

Ozaki M, Kawashima S, Yamashita T, Hirase T, Namiki M, InoueN, Hirata K, Yasui H, Sakurai H, Yoshida Y, Masada M, Yokoyama

2002 27 Diabetologia 2002 07 45 7 1048 1049Impaired glucose tolerance in pancreatic polypeptide-overexpressingmice

Ueno N, Inui A, Asakawa A, Yuzuriha H, Kasuga M, Fujimiya M

2002 28Cytokine 2002 07 19 2 59 65

Local levels of interleukin-1beta, -4, -6 and tumor necrosis factoralpha in an experimental model of murine osteomyelitis due tostaphylococcus aureus

Yoshii T, Magara S, Miyai D, Nishimura H, Kuroki E, Furudoi S,Komori T, Ohbayashi C

2002 29 Urol Res 2002 07 30 3 153 158Diverse patterns of acid-base abnormalities associated with amodified sigmoid neobladder

Fujisawa M, Gotoh A, Hara I, Okada H, Arakawa S, Kamidono S

2002 30 EMBO J 2002 07 21 13 3274 3285 Involvement of Fes/Fps tyrosine kinase in semaphorin3A signalingMitsui N, Inatome R, Takahashi S, Goshima Y, Yamamura H,Yanagi S

2002 31 Spine (Phila Pa 1976) 2002 07 27 14 1526 1530Fas ligand exists on intervertebral disc cells: a potential molecularmechanism for immune privilege of the disc

Takada T, Nishida K, Doita M, Kurosaka M

2002 32 Arterioscler Thromb Vasc Biol 2002 06 22 6 969 974Propagermanium reduces atherosclerosis in apolipoprotein E knockoutmice via inhibition of macrophage infiltration

Yamashita T, Kawashima S, Ozaki M, Namiki M, Inoue N, HirataK, Yokoyama M

2002 33 J Neurosci Res 2002 06 68 5 551 557Rev-erbalpha gene expression in the mouse brain with specialemphasis on its circadian profiles in the suprachiasmatic nucleus

Onishi H, Yamaguchi S, Yagita K, Ishida Y, Dong X, Kimura H,Jing Z, Ohara H, Okamura H

2002 34Genes Cells 2002 05 7 5 447 459

Circadian rhythm of aromatic L-amino acid decarboxylase in the ratsuprachiasmatic nucleus: gene expression and decarboxylating activityin clock oscillating cells

Ishida Y, Yokoyama C, Inatomi T, Yagita K, Dong X, Yan L,Yamaguchi S, Nagatsu I, Komori T, Kitahama K, Okamura H

2002 35 Diabetes 2002 05 51 5 1391 1397Fas/Fas ligand interactions play an essential role in the initiation ofmurine autoimmune diabetes

Nakayama M, Nagata M, Yasuda H, Arisawa K, Kotani R, YamadaK, Chowdhury SA, Chakrabarty S, Jin Z, Yagita H, Yokono K,

2002 36 Pancreas 2002 05 24 4 365 372 Splenic atrophy in experimental severe acute pancreatitisYasuda T, Takeyama Y, Ueda T, Takase K, Nishikawa J, KurodaY

2002 37Am J Transplant 2002 05 2 5 420 424

Successful 24-h preservation of canine small bowel using the cavitarytwo-layer (University of Wisconsin solution/perfluorochemical) coldstorage method

Tsujimura T, Suzuki Y, Takahashi T, Yoshida I, Fujino Y, TaniokaY, Li S, Ku Y, Kuroda Y

2002 38 Eur J Neurosci 2002 04 15 7 1153 1162Gradients in the circadian expression of Per1 and Per2 genes in therat suprachiasmatic nucleus

Yan L, Okamura H

2002 39 Urology 2002 04 59 4 621 625Estrogen levels influence beta-3-adrenoceptor-mediated relaxation ofthe female rat detrusor muscle

Matsubara S, Okada H, Shirakawa T, Gotoh A, Kuno T, KamidonoS

2002 40 Surg Today 2002 04 32 4 335 342An experimental study of regional chemotherapy using CDDP-loadedmicrospheres for esophageal cancer

Nakamura Y, Hamabe Y, Ikuta H, Hyon SH, Kuroda Y

2002 41 Am J Pathol 2002 04 160 4 1335 1344Overexpression of endothelial nitric oxide synthase in endothelial cellsis protective against ischemia-reperfusion injury in mouse skeletal

Ozaki M, Kawashima S, Hirase T, Yamashita T, Namiki M, InoueN, Hirata Ki K, Yokoyama M

2002 42 Kobe J Med Sci 2002 04 48 1-2 25 31Molecular genetics of spinal muscular atrophy: contribution of theNAIP gene to clinical severity

Akutsu T, Nishio H, Sumino K, Takeshima Y, Tsuneishi S, WadaH, Takada S, Matsuo M, Nakamura H

2002 43J Nutr 2002 04 132 4 739 741

Energy metabolism and turnover are increased in mice lacking thecholecystokinin-B receptor

Miyasaka K, Ichikawa M, Ohta M, Kanai S, Yoshida Y, Masuda M,Nagata A, Matsui T, Noda T, Takiguchi S, Takata Y, Kawanami T,Funakoshi A

2002 44 Jpn J Ophthalmol 2002 03 46 2 130 139 Corneal disorders in KKAy mouse: a type 2 diabetes model Watanabe H, Katakami C, Miyata S, Negi A

2002 45 Int J Radiat Oncol Biol Phys 2002 03 52 4 1032 1040Angiosarcoma treated with radiotherapy: impact of tumor type andsize on outcome

Sasaki R, Soejima T, Kishi K, Imajo Y, Hirota S, Kamikonya N,Murakami M, Kawabe T, Ejima Y, Matsumoto A, Sugimura K

2002 46 J Neurosci 2002 03 22 5 2005 2011Deletion of CCK2 receptor in mice results in an upregulation of theendogenous opioid system

Pommier B, Beslot F, Simon A, Pophillat M, Matsui T, Dauge V,Roques BP, Noble F

2002 47 J Ultrasound Med 2002 03 21 3 283 288Low-intensity pulsed ultrasound enhances early healing of medialcollateral ligament injuries in rats

Takakura Y, Matsui N, Yoshiya S, Fujioka H, Muratsu H, TsunodaM, Kurosaka M

2002 48 Neurosci Lett 2002 03 320 1-2 13 16Rhythmic expression of ROR beta mRNA in the mice suprachiasmaticnucleus

Sumi Y, Yagita K, Yamaguchi S, Ishida Y, Kuroda Y, Okamura H

2002 49 Histochem Cell Biol 2002 03 117 3 283 292RANK ligand, RANK, and OPG expression in type II collagen-inducedarthritis mouse

Mori H, Kitazawa R, Mizuki S, Nose M, Maeda S, Kitazawa S

2002 50 Biochem Biophys Res Commun 2002 03 291 3 669 674Synergistic effect of cold mannitol and Na(+)/Ca(2+) exchange blockeron blood-brain barrier opening

Ikeda M, Bhattacharjee AK, Kondoh T, Nagashima T, Tamaki N

2002 51 J Surg Res 2002 02 102 2 161 168 Functional alterations of splenocytes in severe acute pancreatitisUeda T, Takeyama Y, Yasuda T, Takase K, Nishikawa J, KurodaY

2002 52 Pigment Cell Res 2002 02 15 1 67 75Effect of boron neutron capture therapy for melanotic and amelanoticmelanoma transplanted into mouse brain

Iwakura M, Kondoh H, Hiratsuka J, Ehara K, Tamaki N, Mishima Y

2002 53 Diabetes 2002 02 51 2 430 438Synaptic adaptation to repeated hypoglycemia depends on theutilization of monocarboxylates in Guinea pig hippocampal slices

Sakurai T, Yang B, Takata T, Yokono K

2002 54 Surgery 2002 01 131 1 66 74Hematin is one of the cytotoxic factors in pancreatitis-associatedascitic fluid that causes hepatocellular injury

Ueda T, Takeyama Y, Takase K, Hori Y, Kuroda Y, Ho HS

2002 55Arterioscler Thromb Vasc Biol 2002 01 22 1 115 120

Local overexpression of monocyte chemoattractant protein-1 atvessel wall induces infiltration of macrophages and formation ofatherosclerotic lesion: synergism with hypercholesterolemia

Namiki M, Kawashima S, Yamashita T, Ozaki M, Hirase T, IshidaT, Inoue N, Hirata K, Matsukawa A, Morishita R, Kaneda Y,Yokoyama M

2002 56 Arterioscler Thromb Vasc Biol 2002 01 22 1 108 114Involvement of endothelial nitric oxide in sphingosine-1-phosphate-induced angiogenesis

Rikitake Y, Hirata K, Kawashima S, Ozaki M, Takahashi T, OgawaW, Inoue N, Yokoyama M

2002 57 Biochem Biophys Res Commun 2002 01 290 1 225 229Physical interactions of Dmnk with Orb: implications in the regulatedlocalization of Orb by Dmnk during oogenesis and embryogenesis

Iwai K, Oishi I, Xu XZ, Minami Y, Yamamura H

2002 58 Eur J Pharmacol 2002 01 434 1-2 71 79Modulation of airway responsiveness by anionic and cationicpolyelectrolyte substances

Yahata T, Nishimura Y, Maeda H, Yokoyama M

2002 59Oral Oncol 2002 01 38 1 30 34

Establishment and characterization of a human adenoid cysticcarcinoma line of the salivary gland which is serially transplantableand spontaneously metastasises to the lung in nude mice

Umeda M, Komatsubara H, Nishimatsu N, Oku N, Shibuya Y,Yokoo S, Komori T

2002 60 Atherosclerosis 2002 01 160 1 31 39Expression of tissue transglutaminase and elafin in human coronaryartery: implication for plaque instability

Sumi Y, Inoue N, Azumi H, Seno T, Okuda M, Hirata K,Kawashima S, Hayashi Y, Itoh H, Yokoyama M

2002 61 Br J Surg 2002 01 89 1 63 69Preoperative hepatic venous embolization for partial hepatectomycombined with segmental resection of major hepatic vein

Ku Y, Tominaga M, Sugimoto T, Iwasaki T, Fukumoto T,Takahashi T, Suzuki Y, Kuroda Y

2002 62 Circulation 2002 01 105 2 E3 E4Images in cardiovascular medicine. Mouse coronary angiograph usingsynchrotron radiation microangiography

Yamashita T, Kawashima S, Ozaki M, Namiki M, Hirase T, InoueN, Hirata K, Umetani K, Sugimura K, Yokoyama M

2002 63 Neuroscience 2002 01 109 3 407 420Expression of Ca2+/calmodulin-dependent protein kinase (CaMK)Ibeta2 in developing rat CNS

Jusuf AA, Rina-Susilowati, Sakagami H, Terashima T

2002 64 Vaccine 2002 01 20 7-8 1058 1067Dengue type 2 virus subviral extracellular particles produced by astably transfected mammalian cell line and their evaluation for a

Konishi E, Fujii A

2002 65 Cell Transplant 2002 00 11 5 455 457Normalization of blood glucose after islet cografting with placentaltissues in duabetic mice

Suzuki K, Ueda H, Yokono K, Taniguchi H

2002 66 Int Orthop 2002 00 26 5 318 321Comparison of mechanical and histological properties between theimmature and mature tendon attachment

Furikado K, Fujioka H, Kurosaka M, Yoshiya S, Makino T, Fujita K

2002 67 Neuroscience 2002 00 114 2 427 438Abnormal distributions of callosal commissural and corticothalamicneurons in the cerebral neocortex of Shaking Rat Kawasaki

Aoki T, Matsunaga T, Misaki K, Watanabe Y, Terashima T

2002 68 J Orthop Trauma 2002 00 16 418 421Evaluation of an interference screw for tendon reattachment to smallbones

Okuno H, Tanaka J, Maruo S, Fujioka H, Makino T, Watanabe K

2002 69 日本臨床 2002 12 60 12 2269 2275 関節リウマチの疾患関連遺伝子とその機能塩沢俊一，駒井浩一郎，川崎博樹，佐藤優江，中務美紀子，中嶋淑絵，岡山理恵，酒井千菜

2002 70 低温医学 2002 9 283

号83 88

【21世紀における小腸・膵移植のための指針】　二層単純浸漬保存法(二層法)による膵臓・膵島移植

鈴木康之，藤野泰宏，谷岡康喜，酒井哲也，高田壮豊，黒田嘉和

2002 71 日本口腔科学会雑誌 2002 7 514

号244 249

Streptozotosin誘発糖尿病ラットの頬部感染における細菌増殖状況の検討

古土井春吾，吉位尚，大塚芳基，黒木栄司，宮井大介，古森孝英

2002 72 炎症と免疫 2002 6 104

号452 457 慢性関節リウマチの疾患感受性遺伝子探索 駒井浩一郎，塩沢俊一

2002 73 The Lipid 2002 4 13 3 4 9 WHHLウサギ: 動脈硬化病変と心筋梗塞 塩見雅志，伊藤隆

2002 74 日本熱傷学会機関誌 2002 3 281

号42 45 抜去毛包移植による上皮化　ウサギのヒゲと耳介を利用した動物実験 寺師浩人，田原真也，松尾由紀

2002 75 日本疾患モデル学会記録 2002 0 18 18 21 心筋梗塞好発WHHLウサギ，病理所見と心電図所見 塩見雅志，伊藤隆，山田悟士，田村敏昌

2002 76 消化管ホルモン 2002 0 XX 13 16 新規消化管ホルモンGhrelinの作用解析加賀敏宏，乾明夫，浅川明弘，杠葉英樹，永田利謙，瀧本禎之，後藤恭子，水田保子，黒木理恵，春日雅人，藤宮峯子，新

2002 77 消化管ホルモン 2002 0 XX 31 34 膵ペプチド(Pancreatic Polypeptide: PP)過剰発現マウスの解析加賀敏宏，乾明夫，浅川明弘，杠葉英樹，上野尚彦，永田利謙，瀧本禎之，後藤恭子，水田保子，黒木理恵，春日雅人，藤

2002 78 臨床免疫 2002 0 37 6 694 700【関節リウマチ研究の新たな側面】　アデノシン誘導による関節炎の治療

小柴賢洋，小坂英和，中澤隆，熊谷俊一

2002 79 ゲノム医学 2002 0 2 2 21 27 慢性関節リウマチ感受性遺伝子の同定小西良武，川崎博樹，村山公一，駒井浩一郎，佐藤優江，塩沢和子，村田美紀

2002 80 脳と精神の医学 2002 0 13 2 411 417 リーリンシグナル伝達系とアルツハイマー病との関連性 青木拓也，寺島俊雄，柿木達也，渡辺義文

2002 81 脈管学 2002 0 42 291 296 脈管疾患の病態における内皮型NO合成酵素の作用の多様性 川嶋成乃亮，尾崎正憲，山下智也，並木雅行，横山光宏

2002 82 医学のあゆみ 2002 0 201 1 23 27 新規消化管ホルモン, グレリン 浅川明弘，藤宮峯子，乾明夫

2002 83 膝（日本膝関節学会誌） 2002 0 26 176 179関節軟骨に一致した自家骨軟骨移植術における移植軟骨の組織学的検討

牧野健，藤岡宏幸，松井允三，黒坂昌弘，吉矢晋一

2001 1Mol Cell Biol 2001 12 21 24 8329 8335

Loss of mRor1 enhances the heart and skeletal abnormalities inmRor2-deficient mice: redundant and pleiotropic functions of mRor1and mRor2 receptor tyrosine kinases

Nomi M, Oishi I, Kani S, Suzuki H, Matsuda T, Yoda A, KitamuraM, Itoh K, Takeuchi S, Takeda K, Akira S, Ikeya M, Takada S,Minami Y

2001 2 Ann N Y Acad Sci 2001 12 947 419 423Stability of atheromatous plaque affected by lesional composition:study of WHHL rabbits treated with statins

Shiomi M, Ito T, Hirouchi Y, Enomoto M

2001 3 Biochem Biophys Res Commun 2001 11 289 2 548 552Quantitative analysis of papaverine-mediated blood-brain barrierdisruption in rats

Bhattacharjee AK, Kondoh T, Nagashima T, Ikeda M, Ehara K,Tamaki N

2001 4 Eur J Pharmacol 2001 11 431 1 127 131MTP inhibitor decreases plasma cholesterol levels in LDL receptor-deficient WHHL rabbits by lowering the VLDL secretion

Shiomi M, Ito T

2001 5 Psychopharmacology (Berl) 2001 11 158 2 198 204Cholecystokinin2 receptor-deficient mice display altered function ofbrain dopaminergic system

Koks S, Volke V, Veraksits A, Runkorg K, Sillat T, Abramov U,Bourin M, Huotari M, Mannisto PT, Matsui T, Vasar E

2001 6Pancreas 2001 11 23 4 393 398

Possible role of heat shock protein 60 in reducing ischemic-reperfusion injury in canine pancreas grafts after preservation by thetwo-layer method

Fujino Y, Suzuki Y, Tsujimura T, Takahashi T, Tanioka Y,Tominaga M, Ku Y, Kuroda Y

2001 7 Hepatogastroenterology 2001 11 48 42 1577 1578 Differential expression of RAGE in human pancreatic carcinoma cells Takada M, Koizumi T, Toyama H, Suzuki Y, Kuroda Y

2001 8 Pediatr Res 2001 11 50 5 590 595Combination effect of systemic hypothermia and caspase inhibitoradministration against hypoxic-ischemic brain damage in neonatal rats

Adachi M, Sohma O, Tsuneishi S, Takada S, Nakamura H

2001 9 Neuropsychopharmacology 2001 11 25 5 690 698 Behavioral profile of CCK2 receptor-deficient mice Dauge V, Sebret A, Beslot F, Matsui T, Roques BP

2001 10

Bulletin Of Health SciencesKobe

2001 11 17 13 22Influence of electrical and electromagnetic stimulation on nerveregeneration in the transected mouse sciatic nerve: an electronmicroscopic study

Ogata A, Matsumoto T, Matsubara T, Miki A

2001 11 J Neurochem 2001 11 79 4 903 913Generation of a constitutively active fragment of PKN inmicroglia/macrophages after middle cerebral artery occlusion in rats

Ueyama T, Ren Y, Sakai N, Takahashi M, Ono Y, Kondoh T,Tamaki N, Saito N

2001 12J Comp Neurol 2001 10 439 3 275 290

Branchiogenic motoneurons innervating facial, masticatory, andesophageal muscles show aberrant distribution in the reeler-phenotype mutant rat, Shaking Rat Kawasaki

Setsu T, Ikeda Y, Woodhams PL, Terashima T

2001 13 Curr Biol 2001 10 11 19 1524 1527Visualization of mPer1 transcription in vitro: NMDA induces a rapidphase shift of mPer1 gene in cultured SCN

Asai M, Yamaguchi S, Isejima H, Jonouchi M, Moriya T, ShibataS, Kobayashi M, Okamura H

2001 14 Brain Res Brain Res Protoc 2001 10 8 2 126 131Quantification of early blood-brain barrier disruption by in situ brainperfusion technique

Bhattacharjee AK, Nagashima T, Kondoh T, Tamaki N

2001 15 Circulation 2001 10 104 15 1746 1748Angiotensin II induces circadian gene expression of clock genes incultured vascular smooth muscle cells

Nonaka H, Emoto N, Ikeda K, Fukuya H, Rohman MS, RaharjoSB, Yagita K, Okamura H, Yokoyama M

2001 16 Kobe J Med Sci 2001 10 47 5 211 219Unsaturated free fatty acids inhibit Ca2+ mobilization and NO releasein endothelial Cells

Kuroda R, Hirata K, Kawashima S, Yokoyama M

2001 17Br J Oral Maxillofac Surg 2001 10 39 5 376 380

Experimental model of invasion and metastasis by orthotopictransplantation of oral squamous and adenoid cystic carcinomas intothe tongue of nude mice

Umeda M, Yokoo S, Komori T, Nishimatsu N, Shibuya Y, FujiokaM

2001 18Neurochem Int 2001 10 39 4 267 274

Distinct distribution of four Ca2+-dependent subtypes of proteinkinase C in rat olfactory bulb; definite expression of betaII-subtype inthe accessory olfactory bulb

Saito-Ito A, Yagi K, Saito N

2001 19 Eur J Surg 2001 09 167 9 684 688Changes in the number of gut mucosal T-lymphocytes andmacrophages in patients treated by external biliary drainage

Fukuoka K, Ajiki T, Miyazawa M, Takeyama Y, Onoyama H,Kuroda Y

2001 20 Neuroendocrinology 2001 09 74 3 143 147A role of ghrelin in neuroendocrine and behavioral responses to stressin mice

Asakawa A, Inui A, Kaga T, Yuzuriha H, Nagata T, Fujimiya M,Katsuura G, Makino S, Fujino MA, Kasuga M

2001 21 Arthroscopy 2001 09 17 7 747 751Histologic analysis of the implanted cartilage in an exact-fitosteochondral transplantation model

Makino T, Fujioka H, Kurosaka M, Matsui N, Yoshihara H,Tsunoda M, Mizuno K

2001 22 Neurosci Res 2001 09 41 1 13 23 Callosal commissural neurons of Dab1 deficient mutant mouse, yotariAoki T, Setsu T, Okado H, Mikoshiba K, Watanabe Y, TerashimaT

2001 23 Arterioscler Thromb Vasc Biol 2001 09 21 9 1483 1487Expression of glutaredoxin in human coronary arteries: its potentialrole in antioxidant protection against atherosclerosis

Okuda M, Inoue N, Azumi H, Seno T, Sumi Y, Hirata Ki,Kawashima S, Hayashi Y, Itoh H, Yodoi J, Yokoyama M

2001 24Thromb Res 2001 09 103 5 399 409

Involvement of NADH/NADPH oxidase in human platelet ROSproduction

Seno T, Inoue N, Gao D, Okuda M, Sumi Y, Matsui K, Yamada S,Hirata KI, Kawashima S, Tawa R, Imajoh-Ohmi S, Sakurai H,Yokoyama M

2001 25Circulation 2001 09 104 10 1165 1170

Taurine prevents the decrease in expression and secretion ofextracellular superoxide dismutase induced by homocysteine:amelioration of homocysteine-induced endoplasmic reticulum stress

Nonaka H, Tsujino T, Watari Y, Emoto N, Yokoyama M

2001 26 Kobe J Med Sci 2001 08 47 4 181 191Flk-1 specific kinase inhibitor (SU5416) inhibited the growth of GS-9Lglioma in rat brain and prolonged the survival

Takamoto T, Sasaki M, Kuno T, Tamaki N

2001 27Endocr J 2001 08 48 4 443 452

Interleukin-1beta stimulates transendothelial mobilization of humanperipheral blood mononuclear cells with a potential to differentiateinto osteoclasts in the presence of osteoblasts

Tokukoda Y, Takata S, Kaji H, Kitazawa R, Sugimoto T, ChiharaK

2001 28Brain Res Bull 2001 08 55 6 767 774

Effect of neonatal treatment with monosodium glutamate ondopaminergic and L-DOPA-ergic neurons of the medial basalhypothalamus and on prolactin and MSH secretion of rats

Bodnar I, Gooz P, Okamura H, Toth BE, Vecsernye M, Halasz B,Nagy GM

2001 29 EMBO J 2001 08 20 16 4618 4627c-Fos/activator protein-1 transactivates wee1 kinase at G(1)/S toinhibit premature mitosis in antigen-specific Th1 cells

Kawasaki H, Komai K, Ouyang Z, Murata M, Hikasa M, Ohgiri M,Shiozawa S

2001 30 Brain Res 2001 08 911 1 1 11Distribution of Ca(2+)/calmodulin-dependent protein kinase I beta 2 inthe central nervous system of the rat

Rina-Susilowati, Jusuf AA, Sakagami H, Kikkawa S, Kondo H,Minami Y, Terashima T

2001 31 Atherosclerosis 2001 07 157 1 75 84Fibromuscular cap composition is important for the stability ofestablished atherosclerotic plaques in mature WHHL rabbits treated

Shiomi M, Ito T, Hirouchi Y, Enomoto M

2001 32Eur J Drug MetabPharmacokinet

2001 07 26 3 185 192Effects of high-dose troglitaz one on insulin sensitivity and beta-cellfunction in Watanabe heritable hyperlipidemic rabbits

Zhang B, Shiomi M, Tanaka H, Mei J, Fan P, Tsujita Y, HorikoshiH, Saku K

2001 33 Mech Dev 2001 07 105 1-2 153 156Expression of the receptor tyrosine kinase genes, Ror1 and Ror2,during mouse development

Matsuda T, Nomi M, Ikeya M, Kani S, Oishi I, Terashima T,Takada S, Minami Y

2001 34 Brain Res Dev Brain Res 2001 07 129 1 119 123Selective cholinergic denervation inhibits expression of long-termpotentiation in the adult but not infant rat hippocampus

Motooka Y, Kondoh T, Nomura T, Tamaki N, Tozaki H, Kanno T,Nishizaki T

2001 35 Kobe J Med Sci 2001 06 47 3 131 140Tamoxifen interacts with NEU/C-ERBB-2 receptor and inhibitsgrowth of human malignant glioma cell lines

Liu Z, Kokunai T, Tamaki N

2001 36 J Neurosci Res 2001 06 64 6 612 616Constitutive expression and delayed light response of casein kinaseIepsilon and Idelta mRNAs in the mouse suprachiasmatic nucleus

Ishida Y, Yagita K, Fukuyama T, Nishimura M, Nagano M,Shigeyoshi Y, Yamaguchi S, Komori T, Okamura H

2001 37J Clin Microbiol 2001 06 39 6 2178 2183

Human babesiosis in Japan: isolation of Babesia microti-like parasitesfrom an asymptomatic transfusion donor and from a rodent from anarea where babesiosis is endemic

Wei Q, Tsuji M, Zamoto A, Kohsaki M, Matsui T, Shiota T, TelfordSR 3rd, Ishihara C

2001 38 Neurosci Lett 2001 06 306 1-2 41 44Mutant mice lacking the cholecystokinin2 receptor show a dopamine-dependent hyperactivity and a behavioral sensitization to morphine

Dauge V, Beslot F, Matsui T, Roques BP

2001 39Ann Surg Oncol 2001 06 8 5 449 457

Effect of sodium thiosulfate on cisplatin removal with completehepatic venous isolation and extracorporeal charcoal hemoperfusion: apharmacokinetic evaluation

Kusunoki N, Ku Y, Tominaga M, Iwasaki T, Fukumoto T,Muramatsu S, Sugimoto T, Tsuchida S, Takamatsu M, Suzuki Y,Kuroda Y

2001 40 Biol Pharm Bull 2001 06 24 6 683 687Effect of serum triglyceride concentration on the fluctuation of wholeblood concentration of cyclosporin A in patients

Nakamura T, Kakumoto M, Sakaeda T, Nagahiro K, Ohmichi R,Yamashita K, Nishiguchi K, Hirai M, Okumura K

2001 41 Brain Res 2001 05 900 2 157 162The effects of the Na(+)/Ca(++) exchange blocker on osmotic blood-brain barrier disruption

Bhattacharjee AK, Nagashima T, Kondoh T, Tamaki N

2001 42 Diabetes 2001 05 50 5 1206 1210Modest overexpression of neuropeptide Y in the brain leads to obesityafter high-sucrose feeding

Kaga T, Inui A, Okita M, Asakawa A, Ueno N, Kasuga M, FujimiyaM, Nishimura N, Dobashi R, Morimoto Y, Liu IM, Cheng JT

2001 43 Mol Cell Neurosci 2001 05 17 5 921 930Postsynaptic modulation of AMPA receptor-mediated synapticresponses and LTP by the type 3 ryanodine receptor

Shimuta M, Yoshikawa M, Fukaya M, Watanabe M, Takeshima H,Manabe T

2001 44 Int J Mol Med 2001 05 7 5 539 541 Urocortin reduces oxygen consumption in lean and ob/ob miceAsakawa A, Inui A, Ueno N, Makino S, Fujimiya M, Fujino MA,Kasuga M

2001 45 Atherosclerosis 2001 05 156 1 57 66Cerebral atherosclerosis occurs spontaneously in homozygous WHHLrabbits

Ito T, Shiomi M

2001 46 Kobe J Med Sci 2001 04 47 2 47 58Heparin and heparan sulfate inhibit extracellular signal-regulatedkinase activation and myocardial cell hypertrophy induced by

Mizutani K, Kawashima S, Ueyama T, Sakoda T, Takeuchi S,Kobayashi S, Yokoyama M, Hayashi Y, Itoh H

2001 47 Peptides 2001 04 22 4 589 595Proadrenomedullin N-terminal 20 peptide (PAMP) inhibits food intakeand gastric emptying in mice

Ohinata K, Inui A, Asakawa A, Wada K, Wada E, Yoshikawa M

2001 48 Am J Physiol Heart Circ Physiol 2001 04 280 4 H1861 H1868TNF-alpha induces protein synthesis through PI3-kinase-Akt/PKBpathway in cardiac myocytes

Hiraoka E, Kawashima S, Takahashi T, Rikitake Y, Kitamura T,Ogawa W, Yokoyama M

2001 49 Kobe J Med Sci 2001 04 47 2 59 76Prenatal ionizing radiation-induced apoptosis of the developing murinebrain with special references to the expression of some proteins

Kitamura M, Itoh K, Matsumoto A, Hayashi Y, Sasaki R, Imai Y,Itoh H

2001 50 Science 2001 04 292 5515 278 281 Molecular mechanisms of the biological clock in cultured fibroblasts Yagita K, Tamanini F, van Der Horst GT, Okamura H

2001 51 Genes Dev 2001 04 15 8 995 1006Antagonistic role of E4BP4 and PAR proteins in the circadianoscillatory mechanism

Mitsui S, Yamaguchi S, Matsuo T, Ishida Y, Okamura H

2001 52 Circulation 2001 03 103 9 1289 1295Serotonin-induced hypercontraction through 5-hydroxytryptamine 1Breceptors in atherosclerotic rabbit coronary arteries

Ishida T, Kawashima S, Hirata K, Sakoda T, Shimokawa Y, MiwaY, Inoue N, Ueyama T, Shiomi M, Akita H, Yokoyama M

2001 53 Brain Res Dev Brain Res 2001 03 127 1 81 86Different developmental profiles of the expression ofpreprosomatostatin and preprotachykinin-A mRNAs in rat SCN

Nakamura T, Shigeyoshi Y, Maebayashi Y, Yamaguchi S, YagitaK, Okamura H

2001 54Atherosclerosis 2001 03 155 1 45 52

Lysophosphatidylcholine increases the secretion of matrixmetalloproteinase 2 through the activation of NADH/NADPH oxidasein cultured aortic endothelial cells

Inoue N, Takeshita S, Gao D, Ishida T, Kawashima S, Akita H,Tawa R, Sakurai H, Yokoyama M

2001 55 J Biol Chem 2001 03 276 13 10423 10431Regulation of tight junction permeability and occludin phosphorylationby Rhoa-p160ROCK-dependent and -independent mechanisms

Hirase T, Kawashima S, Wong EY, Ueyama T, Rikitake Y, TsukitaS, Yokoyama M, Staddon JM

2001 56 Jpn J Ophthalmol 2001 03 45 2 137 143Altered expression of genes in experimentally induced myopic chickeyes

Akamatsu S, Fujii S, Escano MF, Ishibashi K, Sekiya Y,Yamamoto M

2001 57 Biochem Biophys Res Commun 2001 03 281 5 1291 1297Signaling mechanism underlying COX-2 induction bylysophosphatidylcholine

Rikitake Y, Hirata K, Kawashima S, Takeuchi S, Shimokawa Y,Kojima Y, Inoue N, Yokoyama M

2001 58 Brain Res 2001 03 893 1-2 36 45The effects of cooling and rewarming on the neuronal activity ofpyramidal neurons in guinea pig hippocampal slices

Aihara H, Okada Y, Tamaki N

2001 59 J Ultrasound Med 2001 03 20 3 197 205Low-intensity pulsed ultrasound initiates bone healing in rat nonunionfracture model

Takikawa S, Matsui N, Kokubu T, Tsunoda M, Fujioka H, MizunoK, Azuma Y

2001 60 Life Sci 2001 03 68 15 1761 1767NMDA-responsible, APV-insensitive receptor in cultured humanastrocytes

Kondoh T, Nishizaki T, Aihara H, Tamaki N

2001 61 J Virol 2001 03 75 5 2204 2212Generation and characterization of a mammalian cell line continuouslyexpressing Japanese encephalitis virus subviral particles

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2001 62 Nature 2001 02 409 6821 684 684 View of a mouse clock gene tickingYamaguchi S, Kobayashi M, Mitsui S, Ishida Y, van der Horst GT,Suzuki M, Shibata S, Okamura H

2001 63 FEBS Lett 2001 02 491 1-2 91 93Testosterone inhibits osteoclast formation stimulated by parathyroidhormone through androgen receptor

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2001 64 Gastroenterology 2001 02 120 2 337 345Ghrelin is an appetite-stimulatory signal from stomach with structuralresemblance to motilin

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2001 65 J Comp Neurol 2001 02 430 4 518 532Expression of the Per1 gene in the hamster: brain atlas and circadiancharacteristics in the suprachiasmatic nucleus

Yamamoto S, Shigeyoshi Y, Ishida Y, Fukuyama T, Yamaguchi S,Yagita K, Moriya T, Shibata S, Takashima N, Okamura H

2001 66 Circulation 2001 02 103 7 993 999Statins alter smooth muscle cell accumulation and collagen content inestablished atheroma of watanabe heritable hyperlipidemic rabbits

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2001 67 Arterioscler Thromb Vasc Biol 2001 02 21 2 201 207Endothelial NO synthase overexpression inhibits lesion formation inmouse model of vascular remodeling

Kawashima S, Yamashita T, Ozaki M, Ohashi Y, Azumi H, InoueN, Hirata K, Hayashi Y, Itoh H, Yokoyama M

2001 68 Atherosclerosis 2001 01 154 1 87 96Anti-oxidative properties of fluvastatin, an HMG-CoA reductaseinhibitor, contribute to prevention of atherosclerosis in cholesterol-

Rikitake Y, Kawashima S, Takeshita S, Yamashita T, Azumi H,Yasuhara M, Nishi H, Inoue N, Yokoyama M

2001 69 Neuroreport 2001 01 12 1 127 131Additive effect of mPer1 and mPer2 antisense oligonucleotides onlight-induced phase shift

Wakamatsu H, Takahashi S, Moriya T, Inouye ST, Okamura H,Akiyama M, Shibata S

2001 70Circulation 2001 01 103 2 276 283

An HMG-CoA reductase inhibitor, Cerivastatin, suppresses growth ofmacrophages expressing matrix metalloproteinases and tissue factorin vivo and in vitro

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2001 71 J Biol Chem 2001 01 276 1 693 699Characterization of Fyn-mediated tyrosine phosphorylation sites onGluR epsilon 2 (NR2B) subunit of the N-methyl-D-aspartate receptor

Nakazawa T, Komai S, Tezuka T, Hisatsune C, Umemori H,Semba K, Mishina M, Manabe T, Yamamoto T

2001 72 Diabetes 2001 00 50 A543 A543Co-grafting of islets with placental tissues prolongs survival of allo-grafted islets in diabetic mice without immunosuppressive agents

Suzuki K, Ueda H, Tanioka Y, Deai T, Takahashi T, Kuroda Y,Yokono K, Taniguchi H

2001 73 Neurotoxicity Res 2001 00 3 235 247Effects of sibutramine on the central dopaminergic nervous system inrodents

Nakagawa T, Ukai K, Ohyama T, Gomita Y, Okamura H

2001 74 Acta Chirurgica Austriaca 2001 00 33 65 66Successful allogenic islet trasnplantation without immunosuppressionthrough co-grafting with placental tissues in STZ-induced diabetic

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2001 75 Biomed Res 2001 00 22 3 125 131Different circadian expression profiles of clock genes in the mousesuprachiasmatic nucleus

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2001 76Neuroscience 2001 00 104 2 371 378

Effect of lactate on the synaptic potential, energy metabolism,calcium homeostasis and extracellular glutamate concentration in thedentate gyrus of the hippocampus from guinea-pig

Takata T, Sakurai T, Yang B, Yokono K, Okada Y

2001 77 Acta Histochem Cytochem 2001 00 34 2 135 141Tyrosine hydroxylase and NADPH-diaphorase in the rat nodoseganglion: Colocalization and central projection

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2001 78 J Orthop Res 211 10 29 10 1521 7 Decreased SH3BP2 inhibits osteoclast differentiation and function. Kawamoto T, Fan C, Gaivin RJ, Levine MA, Lietman SA.

2001 79 BJU Int 2119 108 6 914 21

IL-23 gene therapy for mouse bladder tumour cell lines.Kuramoto T, Fujii R, Nagai H, Belladonna ML, Yoshimoto T,Kohjimoto Y, Inagaki T, Hara I.

2001 80 Frontiers in Gastroenterology 2001 10 6 4 79 86 膵ポリペプチド過剰発現マウスによる消化管機能の検討 瀧本禎之，乾明夫

2001 81 Japan Clipping Today 2001 8 8 15 17プラークの安定化には細胞外マトリクスおよび血管平滑筋細胞が重要な役割を果す

塩見雅志

2001 82 環境動物昆虫学会雑誌 2001 8 12 3 147 153 兵庫県千種川流域におけるMetagonimus属吸虫の疫学調査 寒川友貴，宇賀昭二

2001 83 消化管ホルモン 2001 7 19 24 28 ウロコルチン脳室内投与による胃排泄能に及ぼす影響永田利謙，乾明夫，黒木理恵，加賀敏宏，杠葉英樹，浅川明弘，上野尚彦，春日雅人

2001 84 消化管ホルモン 2001 7 19 20 23ヒト血清アルブミン由来のalbutensin Aが摂食およびgastric emptyingに及ぼす影響

大日向耕作，吉川正明，乾明夫，浅川明弘

2001 85 動脈硬化 2001 4 283744

151 155 WHHLウサギの開発，冠動脈疾患と心筋梗塞の発症 塩見雅志，伊藤隆，渡辺嘉雄

2001 86 日本口腔科学会雑誌 2001 3 50 2 90 97ヒドロキシアパタイト（HA）の化学組成が溶出性および骨形成性に与える影響

山田潔，梅田正博，古森孝英，川井隆夫

2001 87 神戸大学医学部紀要 2001 3 61 4 95 101 卵巣摘出による膀胱平滑筋β3アドレナリン受容体機能の変化 松原重治，岡田弘，守殿貞夫，久野高義

2001 88 The Lipid 2001 2 12 2 180 186 プラーク安定化 塩見雅志，伊藤隆

2001 89 日本臨床 2001 2Suppl

2617 620 自然発症高脂血症動物モデル 塩見雅志，伊藤隆