毒物分析 授課教師：賴滄海教授 03-28-2008 lc-ms of drugs of abuse and related compounds
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毒物分析
授課教師：賴滄海教授03-28-2008
LC-MS of drugs of abuse and related compounds
Rapid Commun. Mass Spectrom.2005;19:1332-1338
Development of a multi-target screening analysis for 301 drugs using a QTrap liquid chromatography/tandem mass spectrometry system and automated library searching
Chiral analysis of methadone and its major metabolites (EDDP and EMDP) by liquid chromatography-mass spectrometry
journal of Chromatography B, 814 (2005) 315-323
Doping substances
Diuretics Narcotics β2-Blockers Cannabis Steroids HCG
Erythropoietin Stimulants HGH Insulin,
HBOC
Figure 9.1 Diuretics with thiazide structure are converted by hydrolysis or sulphoxidation during sample transportation, storage or preparation, which may cause analytical problems in GC-MS. Respective artefacts need to be factored into LC-MS screening
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