ebs mg so4 and sah
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Magnesium for aneurysmal SHA: panacea or illusion?
EBS presentation 26/07/2012
David Bervini, Nazih Assaad
Searchable question
• “Is i.v. MgSO4 treatment effective in improving the outcome of patient experiencing aneurysmal SAH?”
• Databases– Ovid Medline, using MeSH– Ovid EMBASE, using Emtree– Scopus using review articles and tracking references– The Cochrane Collaboration
• P Patient with aneurysmal subarachnoid haemorrhage
• I i.v. MgSO4
• C no MgSO4
• O clinical outcome
Medline VS EMBASE
Search strategy
Cochrane 2008
• MgSO4 VS placebo in addition of nimodipine
National Health and Medical Research Council (NHMRC) Evidence Hierarchy
• At least 6 level II studies
• At least 10 level I reviews (including Cochrane)
Conclusion and discussion
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