gangguan pubertas kel.ppt 2
Post on 04-Nov-2015
74 Views
Preview:
DESCRIPTION
TRANSCRIPT
-
PUBERTY
-
Precocious Puberty
-
ClassificationGnRH dependent (central) : premature reactivation hypothalamus-pituitary-gonad axis increased gonadotropin increased sex steroids (dependent)Usually idiopathicGnRH independent (peripheral): autonomous sex steroid secretion, depressing the hypothalamus-pituitary-gonad axisUsually pathologic
-
Classification Variantpremature thelarchepremature adrenarchegynecomastia
-
HypothalamusPituitaryGnRHGonadLH/FSHE2 or T(-)H-P-G axis
-
HypothalamusPituitaryGnRHGonadLH/FSHSex steroid (-)H-P-G axis in GDPPPrimary
-
HypothalamusPituitaryGnRHGonadLH/FSH(-)Extra GonadalH-P-G axis in GIPPSex steroid PRIMARY
-
ConclusionNot all pubertal disorders are pathologicEarly increase of sex steroid should be thoroughly investigatedGnRH agonist = drug of choice for GDPP
-
LHRHLH/FSHHipotalamusHipofisisTarget Organ(gonad)Sex Steroid Primary defectHipergonadotropik(-)
-
LHRHLH/FSHHipotalamusHipofisisTarget Organ(gonad)Sex Steroid Primary defectHipogonadotropik(-)DELAYED PUBERTY
-
KESIMPULANPubertas berlangsung menurut stadium, umur tertentuPubertas harus selalu menjadi perhatian orangtua / tenaga kesehatanSetiap tenaga kesehatan dapat mendeteksi kelainan pubertas secara dini dan segera melakukan rujukan
top related