professor phil coates - welcome to the polymer irc! | …€¦ ·  · 2017-01-11professor phil...

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中英科技桥中英科技桥

ResearchProfile

SUMMARYOFMYRELEVANTRESEARCHAREAS:Structuring of polymers, composites and nanocomposites by processing; in-process measurementsorientedpolymers;biomaterials;specialistprocessingincludingmicromoulding,solidphaseorientationprocessingandreactiveprocessing;polymerrheology;computermodellingofprocessingandproducts;expertiseinrunninglargescaleinterdisciplinaryresearchprogrammes通过加工技术达成聚合物，复合材料和纳米复合材的结构化;过程测量（光学，流变光，热量，超

声波，光谱，散射;定向聚合物；生物材料；包括微米铸模成形，固相取向加工和反应处理等的专

门加工;聚合物流变; 加工及制品的计算机建模；运行大型跨学科研究项目的专长。

PrimaryResearchinterests:ProfessorPhilCoatesisaPhysicsgraduate(ImperialCollege),withPhDresearchonsolidphasedeformationprocessingofpolymers(Leeds).PhilisDirectoroftheinternationallyrecognisedPolymerInterdisciplinaryResearchCentre(IRC).Mainresearchprojectsinclude:Healthcare: • bioresorbable shape memory materials for bone and soft tissue fixation •micromoulded precision products • enhanced design & modelling of tools for minimallyinvasivesurgery•novelextrusionmanufacturingofdrugs•jointrepair; Basicscience:•Moleculararchitectureeffectsonprocessing•in-situprocesscharacterisationof polymers • ultra-high strain rate rheometry • rheo-optical studies of extrusion and co-extrusion•SANSofdeuteratedmelts•shearenhancedcrystallisation•AFMofpolymers,biomedicalmaterials,tissueandnanocomposites;Novel& efficient processing: •Micromoulding process developments andmeasurements•solidphaseorientationprocessing–diedrawing•processingofnanocomposites•multi-feedreactiveextrusiongrafting•fluid-assistedinjectionmoulding•injectionmouldingcontrol•extrusionqualitycontrol•additivescompounding•thermalalloytooling;In-processmeasurements: include•processultrasound,•at-processUV&Ramanspectroscopy,•at-processcolourmeasurement,•processenergy,•temperaturefields•rheo-optical,•in-situbeamstudiesofstructure;Modelling:•multi-scalemodellingfornanocomposites•fibreorientationmeasurementandpredictionininjectionmoulding•FEAofprocessandproductsTopicsinwhichyouwouldliketodevelopcollaborativeresearch:Tailored Polymers, polymer nanocomposites or polymer blends which can have theirmorphology developed during processing, to achieve properties which are suitable, forexample,formedicaldevicesandtherapiese.g.(a)boneanalogues,fixationsystems,scaffolds,stents,drugelutingproducts,. Potentialprocessesinclude: (i)micromoulding,(ii) injectionmoulding,(iii)extrusion,(iv)solidphaseorientation;(v)reactiveprocessing;with(vi)materialscharacterisation (duringprocessingandoff line)and (vii) computermodellingandcontrolofquality.

Name: ProfessorPhilCoatesPosition: Director,PolymerIRC;DirectorRCUKBradfordScienceBridges

ChinaInstitute/division: SchoolofEngineering,Design&Technology,UniversityofBradfordEmail: p.d.coates@bradford.ac.ukTel: (00)441274234540

Shapememory

bioresorbablefixation

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中英科技桥中英科技桥

Relevantexistingcollaborations(academic/clinical/commercial)insideoroutsideChina.Include:China:ScienceBridgesChinaprojectswith*SichuanUniversity(+MOST,NSFC,MoEinternationalprojects),*BeijingUniversityofChemicalTechnology,*InstituteofChemistryCASBeijing,InstituteofAppliedChemistryCASChangchun;HKUST.*Bradford-JointInternationallaboratory.UK:Leeds,Durham,Sheffield,Newcastle,Nottingham,QueensBelfast,Oxford,Cambridge,Warwick,UCL.Industry:over150companiescollaborating,including:Arterius,Autodesk,Invibio,Sabic,Sinopec,Smith&Nephew,SurgicalInnovations,Xplore.

Relevantgraphics,figures,pictures:

‘Processstructuring’:(i) Diedrawing–solidphaseorientationprocessing (ii)MicromouldingWithDrFinCaton-Rose&team withDrBenWhiteside&team

Someofthein-processmeasurementsweundertake SOMEMEDICAL/BIOMEDICALRESEARCHAREAS:

Rheo-optical:flowbirefringencewithDrTGough,DrMMartyn

Shapememorypolymersfortissuefixations orientedpolymerstents

minimallyinvasivesurgerydevices

Orientedpolymersforanisotropicdrugdelivery AtomicForceMicroscopyof withProfParadkar&DrKelly) collagenoustissuesclera,whiteofCavitatedlowdensityorientedpolymersforstructuralproducts eye(DrCGrant)

Publicationsandotheroutputsrelevanttoyourinterestinthisprogramme• Bent,L.R.Hutchings,R.W.Richards,T.Gough,R.Spares,P.D.Coates,I.Grillo,O.G.Harlen,D.J.Read,R.S.Graham,A.E.Likhtman,D.J.Groves,T.M.

NicholsonandT.C.B.McLeish,Neutron-MappingPolymerFlow:Scattering,FlowvisualizationandMolecularTheory,Science,301,1691-1695(2003)• A.L.Kelly,T.Gough,B.R.Whiteside,PDCoates,HighShearStrainRateRheometryofPolymerMelts,JAppPolySci,114,864–873,(2009)• LiL;Mulvaney-JohnsonL;ChenN;WangQ;CoatesPDSmallscaleinjectionmouldingofmodifiedpoly(vinylalcohol),39(9),411-418,1465-8011,Plast

RubbComp.2010• G-XFei,CTuinea-Bobe,D-XLi,GLi,BWhiteside,PDCoatesandH-SXia,Electro-activatedsurfacemicropatterntuningformicroinjectionmolded

electricallyconductiveshapememorypolyurethanecomposites RSCAdvances,12/2013;3(46):24132-24139.DOI:10.1039/C3RA43640C 2013

• Z-YJiang,Y-TWang,L-LFu,BWhiteside,JWyborn,KNorris,Z-HWu,PDCoates,andY-FMen.TensileDeformationofOrientedPoly(ε-caprolactone)andItsMiscibleBlendswithPoly(vinylmethylether) Macromolecules,Vol.46,No.17,pp.6981−6990;DOI:10.1021/ma401052x. 2013

• JiajiaXue,RuiShi,YuzhaoNiu,MinGong,PhilCoates,AileenCrawford,DafuChen,WeiTian,LiqunZhang Fabricationofdrug-loadedanti-infectiveguidedtissueregenerationmembranewithadjustablebiodegradationproperty ColloidsandSurfacesB:Biointerfaces,18March.DOI:10.1016/j.colsurfb.2015.03.031,2015

• Li,Zhengqiu;Zhao,Xiaowen;Ye,Lin;Coates,Phil;Caton-Rose,Fin;Martyn,Michael,Structureandbloodcompatibilityofhighlyorientedpoly(l-lacticacid)chainextendedbyethyleneglycoldiglycidylether.Polymer;56;523-534;DOI:10.1016/j.polymer.2014.11.035,2015

HeatedPolymer(Tg<T<Tm) HeatedDieFreeDrawing

region

DrawingLoad

AoAf

Axialstrainrate

dieangle F

0200400600800100012001400160018002000

0 20 40 60 80 100 120

μgofp

aracetam

olreleasedperday

*(no

rmalisedpergramofthero

dpercm

2

surfacearea.

Daysinthereleasemedium

Drugreleasefromλ=4XPLArodsCrosssection

Lateralsurface

Local Heat

Shape Memory bioresorbablepolymer with

cannulation and microgrooves for sutures(Φ2mm)

μCT of recovered shape

interference force

generated by shape

recovery

Φ8mm surgical incision in bone