prolactin oma 1
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PROLACTINOMA
Bautista, Karen
Dela Cruz, Christian Lherry
Mendoza, Kaori
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What is a prolactinoma?
a benign tumor (called an adenoma) of the
pituitary gland
produces an excessive amount of the
hormone prolactin in the blood
the most common type of pituitary tumor
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What causes prolactinomas?
abnormal increase in number of prolactin-
producing cells --- (Pituitary Lactotrophic
Acidophil Cells)
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What are the signs and symptoms?
In WOMEN:
-irregular periods or no periods (amenorrhea)
-breast tenderness-infertility
-reduced sex drive
-galactorrhoea
-increased growth of hair on the face or
body
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What are the signs and symptoms?
In MEN:
reduced fertility
erectile dysfunction (difficulty having an
erection)
reduced libido
breast enlargement (gynaecomastia).
very rarely, leakage of milk from the
breasts.
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What are the signs and symptoms?
Children and teenagers may have:
reduced growth
delayed puberty
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How is prolactinoma diagnosed?
may be suspected from the symptoms
Women tend to be diagnosed earlier than
men----- a change in the woman's periods
is an early symptom and is easily noticed
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How is prolactinoma diagnosed?
Magnetic Resonance Imaging (MRI)
-the most sensitive test for detecting
pituitary tumors-determines the size of the tumor
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How is prolactinoma diagnosed?
Computed Tomography (CT scan)
- also gives an image of the pituitary, but itis less sensitive than the MRI.
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How is prolactinoma diagnosed?
Blood tests
normal prolactin level in blood is:
women: 1-25 ng/mL
men: 1-20 ng/mL
A very high prolactin level (>200ng/mL)usually means that a prolactinoma is present
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What is the treatment for
Prolactinoma?
Drugs Bromocriptine
Cabergoline
Surgery
should be considered if medical therapy
cannot be tolerated
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THANK YOU
FOR
LISTENING
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