sintesis protein oleh sel
Post on 21-Feb-2018
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7/24/2019 Sintesis Protein Oleh Sel
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Sintesis protein oleh sel
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RF + GTP
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Inhibitor of Protein Synthesis in Eukaryotes
Abrin, Ricin Inhibits binding of aminoacyl t-RNA
iphtheria to!in "ataly#es a reaction bet$een NA and E%& toyield an inacti'e factor( Inhibits translocation
"hloramphenicol) Inhibits peptidyltransferase of mitochondrialribosomes( Is inacti'e against cytoplasmic
ribosomes Puromycin) "auses premature chain termination by acting
as an analogue of charged t-RNA
%usidic acid) Inhibits translocation by altering an elongationfactor
"yclohe!imide Inhibits peptidyltransferase Pactamycin Inhibits positioning of t-RNA*+eton the S
ribosome
Sho$domycin Inhibits formation of the E%&-tRNA*+et./Pcomple!
Sparsomycin Inhibits translocation*also active on prokaryotic ribosomes
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Antibiotics Inhibitor of Protein Synthesis in
Prokaryotes
/etracycline Inhibits positioning of t-RNA on A side in ribosome
Strptomycin Inhibits formation of theE%&-tRNA*+eton the 0 Sribosome
"hloramphenicol Inhibits peptidyltransferaseon ribosome
Erythromycin Inhibits translocation
Rifamycin Inhibits RNA synthesisbinding to RNA polymerase
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1ambatan pembentukan protein
Antibiotik menghambat pembentukan
protein bakteri
2irus mengganggu NA atau RNA
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