Slide 1

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. . .

, plug-in = , . . :

s(X) , t(F) , , , " .

: , "

, :

Example: the patch data : . : , . , 3 : , "", , . . .

: , . , , , . Z=oldpatch-placeboY=newpatch-oldpatch

" FDA . FDA. , . FDA -

, FDA , 20% .

. - 2 , zi yi 8 ' old-plant. " -

.

-

0.20, FDA. . 400 8 . : y z , . .

B=400

: , .041. : 0.25 , [ ]. MSE. MSE :

. 1. = 0,

MSE 3.1% . B=400 . ? .

: . - ( ), ( ). B=400 (0.0105 2 0.0043!)

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