biomaterial obs
TRANSCRIPT
7/23/2019 Biomaterial Obs
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BIOMATERIALIN ORTHOPAEDICS
7/23/2019 Biomaterial Obs
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OUTLINE
Defnisi Sejarah Karateristik Biomaterial
Biocompatiilit! Biomaterial Science Contoh Pen""#naan Biomaterials
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Defnisi
$aterial %ari #ns#r alam !an" telah %iolah
se%emikian r#pa !an" %i"#nakan #nt#kkeperl#an men""antikan ata#menin"katkan &#n"si or"an %an jarin"anman#sia'
7/23/2019 Biomaterial Obs
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Sejarah
(eih %ari )*** tah#n !l oran" Roma+i,China, memakai emas %lm i%an"ke%ok'"i"i'
-./0 Pol!1meth!l methacr!late2 1P$$A2m#lai %iperkenalkan %alam ke%ok'"i"i'
-.3* Charnle! men""#nakan P$$A,#ltrahi"h4molec#lar4+ei"ht pol!eth!len%, %an
stainless steal #nt#k total hip replacement'akhir-.3* 5 a+al -.0* i%an" iomaterialsemakin erkeman"'
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Karakteristik
S!arat 6isikHar%78e9ile $aterials'
Resisten terha%ap korosi %an
%e"ra%asi #ns#r' S!arat kimia+i
Ti%ak oleh ereaksi %en"an
jarin"an t##h apap#n Har#s non4to9ic
7/23/2019 Biomaterial Obs
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Metals
SemicondctorMaterials
!eramics
"ol#mers
S#ntheticBIOMATERIALS
Ortho$edicscre%s&f'ation
DentalIm$lants DentalIm$lants
(eart
)al)es
Bonere$lacements
BiosensorsIm$lanta*leMicroelectrodes
Skin&cartila+eDr+
Deli)er#De)ices
Oclarim$lants
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Biocom$ati*ilit#
Kemamp#an %ari se#ah material#nt#k ti%ak menim#lkan responiolo"is %en"an ti%ak menim#lkanrespon toksis,ce%era leih %alam %anrespon im#nolo"is %ari jarin"an hi%#p%isekitarn!a'◦ San"at %itent#kan oleh str#kt#r kimia+i !a
a%a %i material !an" %i"#nakan'
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Reaksi terhada$Biomaterial Thromosis Hemol!sis In8ammation
In&ection an% Sterili:ation Carcino"enesis H!persensiti;it! S!stemic E<ects
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!ontoh $en++naan Biomaterial,$ada T(R-
Da hal $entin+ dalam menem$elkan materialke tlan+
-2 Posisi "eometris %an %esain material
%ari perm#kaan sen%i)2 %esain %ari pertem#an perm#kaan
antara sen%i #atan %an t#lan"sekitarn!a'
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using a Polymethylmethacrylate
(PMMA) cement to adhere the
metal to the bone
using a porous metal
surface to create a bone
ingrowth interface
Metoda $enem$elan $ermkaanim$lan dan tlan+
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The two materials are
bonded and equal force is
applied to both
Load trans.er $ada materialim$lan #an+ di+nakan
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Im$lant *ondin+
A bonded interface is
characteristic of a
cemented prosthesis
(left)
non-bonded interface is
characteristic of a non-
cemented press fit
prosthesis (right)
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The material>s capailit! to +ithstan%
e9ternal &orces can e %escrie%, there&ore,in terms o& the %istri#tion o& internal &orces"enerate% ! the material 1the stress2 an%the res#ltin" %e&ormation 1the strain2'
Stress )s Strain ,elastic*eha)ior-
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Stress? (oa%7l#as area @ Ne+ton7m)
Strain? elon"ation7panjan" area !" %i#k#r seel#mterkena "a!a @ micron7mm @ microstrain
Stress 7 Strain @ $o%#l#s Elasticit! 1i"aPascal2
$o%#l#s o& Elasticit! akan konstan #nt#k tiap)material,%an k#r;a stress7strain erent#k linier'
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!om$arison/ Modls o.Elasticit#
Modulus of elasticity of different implant materials and bone (in GPa)
7/23/2019 Biomaterial Obs
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ika loa% ter#s menin"kat, k#r;aStress7strain akan ti%ak la"i linier, %an ilaloa% %ilepas, material akan men"alamiplastic %e&ormation 1permanent%e&ormation2'
$aterial men"alami titik jen#h #nt#kkemali elastis'
Titik jen#h ini %apat menent#kan kriteriake"a"alan 1&ail#re2 %ari se#ah material
"lastic Beha)ior
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Ti%ak sem#a material memiliki plasticeha;ior
Titik &ail#re eerapa material lan"s#n"terja%i saat titik jen#h elastisitas tercapai'
$aterial !an" memp#n!ai si&at seperti ini%ise#t rittle material'
Contoh? P$$A 1Polymethylmethacrylate)
Dctile 0erss BrittleBeha)ior
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Plate, men"alami kominasi eerapa "a!asea"ai loa% n!a, semisal a9ial compressi;eloa%, en%in" loa%, e9ternal torF#e'
Data %ari tes) !an" %ilak#kan terha%apeerapa material %apat %i"#nakan #nt#kmemperkirakan titik &ail#re %ari material!an" %i"#nakan'
!om*ined Stress States
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ika se#ah plate %i pasan" %en"an loa% %ariera"ai i%an", plate terse#t %ikatakanisotropic ila men%apatkan "a!a !an" sama%i / i%an"
Isotro$ic 0s Anisotro$icBeha)ior
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Si&at s#at# material !an" men"hamatkarakter ;isco#s %an elastic %ari materialterse#t saat men"alami per#ahan
ent#k' $o;ements o& molec#les ? Creep
)iscoelasticit#
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6ail#re criteria, Giel% 5 ltimate stren"th $a9im#m tolerale loa%
1ati2e