Drug addiction : a computational multiscale model combining neuropsychology , cognition and behavior

Drug addiction :a computational multiscale model combining neuropsychology , cognition and behaviorBiosignals 2009 international conference of bio inspired systems and signal processing

Yariv Z. Levy, Dino Levy, Jerrold S. Meyer and Hava T. Siegelmann

: 2006 ( ) : 24.7 16 12 ( 2008)

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/ . ( ) ( 2008) . (drug seeking behavior) . :

: . ( 2008) . : . . ( .. 2007) : . ( 100%) ( 1962 .. 2000)5 ( 2008) . . . : neuropsychological (NepS) cognitive (CogS) behavioral (BehS) .

G(t) : ( ) :G(t)=(1-r(t)).(-C(t))+r(t).I(t)r(t) : C(t) I(t) :

Neuropsychological scale (Neps)

() P(t) : ( ) ( .. 2004)S(t) : ( .. 1995 2001 2004) ( 2000)D(t) : nucleus accumbens (NAc)q(t) : cue ( 2005) cue AP(t) : ( 2006)AS(t) : () ( .. 1996)AD(t) : ( 1983 .. 1999)Q(t) : cue ( 2002) NepS G(t)

Coginitive scale (CogS) f(t) : NepS

r(t) :

r(t) f(t)

r [0,1]Behavioral scale (BehS)G(t)

G(t)[-1,1]

G(t) > 0 : ( )

G(t)