~ 全美华人病理学会 ~

CAPA e Newsletter

volume 4 issue 2 2018

In this issue: A Note from President

D ear all CAPA members, I am a

little over four months into my new role as CAPA president. It has been a great honor for me to work with dedicated and capable EC members and other members around the goals that I listed at the beginning of my term in March this year. At the 1st EC meeting, we advocated a healthy culture of mutual respect and support as well as active communication among EC members to ensure running CAPA in a transparent and democratic way, which is essential to the growth and success of our society. Over the last four months, I am truly touched by the efforts that you have put to make CAPA better. Several educational events are going on smoothly. Online lectures are well-received as always. The preparations for the 4th CAPA Diagnostic Pathology Course in New York, the 4th Sino-US Cancer Diagnostic Pathology Summit in Beijing, and the CAP/CAPA Companion Meeting in Chicago are in their active phase. In addition, CAPA Bylaws amendment, website update, and eNewsletter publication are going well and in a timely fashion as expected. Of note, EC has spent a huge amount of time on finance issues including internal and

external finance review, and investigation for practical strategies to apply for 501c. After finance review by professionals and consultation with CPA and attorney, we are armed with a deeper understanding that, for the best interest of CAPA, we need to reform it in order to change its tax-exempt status by applying for 501c. The detailed information of the work is highlighted in the Progress Report of CAPA Issues. I greatly appreciate each of you who made contributions. We still have a lot to do in the year ahead. I will keep you informed as plans for all the events move forward. I’d like to have your inputs which will help me and the rest of leadership team in determining the best way to approach our goals. In addition, I am asking that you show your commitment to our society by actively participating in our educational events and involving in voting for the amended Bylaws, which will be ready soon. Making CAPA greater is our common goal and this can only be achieved by all of us working together. I am looking forward to seeing you in CAPA diagnostic course in New York in August. Sincerely yours,

Yun Gong, MD CAPA president 2018-1019 MD Anderson Cancer Center

A Note from Presi-dent

P1

The 4th CAPA Diag-nostic Pathology Course Announce-ment

P2-P4

The 4th CAPA Diag-nostic Pathology Course Program

P5-P7

Progress Report of CAPA Issues

P8

Recent Achievements from CAPA Members

P9-P10

Report to CAPA eNewletter

P10

Case of Quarter (COQ)

P11-P12

Recipes of Quarter

(ROQ)

P13

Acknowledgements and Advertisements for CAPA Sponsors

P14

Editor-in-Chief and Designer :

Fan Chen

Editing Team:

Feng Li Xiangdong Xu Guilan Chen Yanxia Li Fang Wen

The 4th CAPA Diagnostic Pathology Course Announcement

When: Saturday, August 25th ─ Sunday, August 26th, 2018

Where: Sheraton LaGuadia East Hotel, Flushing, New York

13520 39th Ave, Flushing, NY, 11354, Phone: 718-670-7408

The 4th CAPA Diagnostic Pathology Course will be held in August 25-26, 2018 at Sheraton LaGuadia East Hotel, Flushing, New York. This one-and-half-day course will offer essential knowledge and updated information in a variety of subspecialties, including Head & Neck, GI, Hematopath, Breast, GYN, GU, Cytopathology, Molecular Pathology, Forensic Pathology, and Interesting Cases. The course will provide up to 14.5, but 8.75 for each attendee AMA PRA Category 1 Credits. In addition, there are two fun sessions in Sunday morning. Career Development Session provides attendees opportunity to chat with experienced senior CAPA members (from both academic and private practice) and discuss professional-related issues; Photographic Session is prepared for those who are keen on photography.

Sponsored by Chinese American Pathologists Association (CAPA) Meeting agenda: http://www.capa-ht.org/wp-content/uploads/2018/06/The-4th-CAPA-Diagnostic-Course-06-23-2018.pdf.

Payment Options: 1) Online payment through PayPal (http://www.capa-ht.org/meetings/). Major credit cards work with PayPal. 2) Onsite payment by personal check Should you have any questions, please contact Dr. Zenggang Pan at (402) 320-7437 or “panzenggang@yahoo.com”.

(Cont’d on Page 3)

The 4th CAPA Diagnostic Pathology Course (Cont’d)

(Cont’d from Page 2)

Organizing Committee

Yun Gong, Ximing Yang, Hanlin Wang, Ruliang Xu, Huan-You Wang, Wei Xin, Steven Shen, Lanjing

Zhang, Lizhen Gui, Yingxian Liu (Mark), Peng Lee, Huihong Xu, Zongming Chen (Eric)

Conference Overview

This 2-day course provides in-depth coverage on the hot topics including recent advance in molecular

pathology and practical topics including those commonly encountered in daily diagnostic pathology in

a format of didactic lectures and case-based presentations. The course will be presented by national

experts across all subspecialties of diagnostic pathology. The course will address the questions and

challenges and provide the updates and pearls in diagnostic pathology that practicing pathologists

encounter in day-to-day practice, help the practicing pathologists to avoid the commonly encountered

diagnostic errors and become proficient in different subspecialties, and help residents and fellows with

their subspecialty board exam preparations. The interesting case discussion will provide ample

opportunity for pathologists from academic and private practice to have face-to-face discussions.

Intended Audience and Conference Objectives This course is intended primarily for practicing pathologists, fellows, residents and other health care

professionals. At the conclusion of this course, participants should be able to:

Describe the recent advance in molecular pathology in each subspecialty

Recognize the diagnostic traps that are commonly encountered in daily pathology practice

Demonstrate improvement in diagnostic skills in handling problematic cases

Accreditation

This activity is being applied to the Princeton HealthCare System CME committee. Princeton

HealthCare System may provide continuing medical education for physicians. (A total of 14.5, but 8.75

for each attendee AMA PRA Category 1 Credit(s)™)

Registration Please register through: https://goo.gl/forms/S4p9hE4UuCfafiUH3

Please pay through: www.capa-ht.org/meetings/

Fees: Regular/lifetime member, $100; Nonmember, $150; Faculty, No fee

Should you have questions, please contact Dr. Zenggang Pan: (402) 320-7437, or

“panzenggang@yahoo.com”

Parking Sheraton LaGuadia East Hotel, Flushing, New York;

Parking fee: $14/day (Cont’d on Page 4)

The 4th CAPA Diagnostic Pathology Course (Cont’d)

(Cont’d from Page 3)

Faculty List (Alphabetically)

Guoping Cai, MD (Yale University) Beiyun Chen, MD, PhD (Mayo Clinic) Yihua Chen, MD (Northwestern University) Zongming Chen (Eric) (MD, PhD (Geisinger Medical Center) Fang Fan, MD, PhD (University of Kansas) Jerald Z Gong, MD (Thomas Jefferson University) Yun Gong, MD (MD Anderson Cancer Center) Lizhen Gui, MD, PhD (Northwest Arkansas Pathology Associates) Charles Guo, MD (MD Anderson Cancer Center) Jiaoti Huang, MD, PhD (Duke University) Pei Hui, MD, PhD (Yale University) Peng Lee, MD, PhD (NYU) Faqian Li, MD, PhD (University of Minnesota) Feng Li, MD, PhD, JD (Medical Examiner’s Office, Davidson County and Metropolitan Nashville) Shaoying Li, MD (MD Anderson Cancer Center) Xiaoxian Li (Bill), MD, PhD (Emory University) Fan Lin, MD, PhD (Geisinger Medical Center) Jingmei Lin (Indiana University School of Medicine) Pei Lin, MD (MD Anderson Cancer Center) Chen Liu, MD, PhD (Robert Wood Johnson Medical School, Rutgers University) Jinsong Liu, MD, PhD (MD Anderson Cancer Center) Xiuli Liu, MD, PhD (University of Florida Health) Yingxian Liu (Mark), MD (Brooklyn Hospital, NY) Zenggang Pan, MD, PhD (University of Colorado) Yan Peng, MD, PhD (UT Southwestern Medical Center) Qinghu Ren, MD, PhD (NYU) Steven Shen, MD, PhD (Houston Methodist Hospital/Cornell University) Xiaoping Sun, MD, PhD (MD Anderson Cancer Center) Beverly Wang, MD (UC Irvine) Hanlin Wang, MD, PhD (UCLA) He Wang, MD, PhD (Robert Wood Johnson Medical School, Rutgers University) Jun Wang, MD (Loma Linda University) Sa Wang, MD (MD Anderson Cancer Center) Yanhua Wang, MD (Montefiore Medical Center/Albert Einstein College of Medicine) Jianjun Wei, MD (Northwestern University) Sang Wu, MD (Texas Health Presbyterian Hospital) Wei Xin, MD, PhD (Case Western Reserve University) Haodong Xu, MD, PhD (University of Washington) Huihong Xu, MD, MS (Boston University) Ruliang Xu, MD, PhD (NYU Langone Medical Center) Hongyu Yang (Henry) MD, PhD (St Vincent Evansville Hospital, Evansville, IN) Hua Yang, MD (University of Calgary) Jack Yang, MD (Medical University of South Carolina) Ximing Yang, MD, PhD (Northwestern University) JinJuan Yao, MD, PhD (Memorial Sloan Kettering Cancer Center) Limin Yu, MD (Beaumont Health Care) Lanjing Zhang, MD, MS (Princeton HealthCare System/Rutgers University) Miao Zhang, MD, PhD (MD Anderson Cancer Center) Xinmin Zhang, MD (Cooper University Hospital, New Jersey) Xuchen Zhang, MD, PhD (Yale University) Yaxia Zhang, MD, PhD (Hospital for Special Surgery, Weill-Cornell School of Medicine, NY) Wenxin Zheng, MD (UT Southwestern Medical Center) Minghao Zhong, MD (New York Medical College) Ming Zhou, MD, PhD (UT Southwestern Medical Center)

The 4th CAPA Diagnostic Pathology Course Program

Saturday (August 25th) 7:30 am - 4:00 pm

Day 1, Room A

7:30 - 8:20 am Registration and Breakfast (provided by CAPA)

Time Speaker Title

8:20 - 8:30 am Yun Gong Welcome and Introduction

Session 1 A Molecular/thoracic, H&N Moderators: Hao-dong Xu, Ruliang Xu

8:30 - 8:55 am JinJuan Yao MSK-IMPACT: Beyond Next Generation Se-quencing

8:55 - 9:20 am Ruliang Xu Practical molecular pathology in GI tract

9:20 - 9:45 am Haodong Xu An update on diagnostic biomarkers for ma-lignant pleural mesothelioma

9:45 - 10:10 am Faqian Li Practical approach to the diagnosis of small cell carcinoma in small biopsy specimens

10:10 - 10:30 am Break

Session 2 A GI/liver/pancreas Session Moderators: Xiuli Liu, Hanlin Wang

10:30 - 10:55 am Xiuli Liu Reading IBD surveillance biopsy like a Pro: Everyone can do it!

10:55 - 11:20 am Xuchen Zhang An update in liver neoplasm

11:20 - 11:45 am Zongming Chen (Eric) Gastric adenoma: differential diagnosis and clinical implication

11:45 - 12:10 pm Wei Xin Interesting and challenging colon polyps

12:10 - 1:30 pm Lunch (provided by CAPA); possible promotion talk in a separate room

Session 3 A Hemepath Session Moderators: Sa Wang, Jun Wang

1:30 - 1:55 pm Jun Wang Post-transplant lymphoproliferative disorders (PTLD)

1:55 - 2:20 pm Pei Lin High grade B-cell lymphoma: practical issues

2:20 - 2: 45 pm Yihua Chen Peripheral blood review: finding diagnostic clues to hematologic disorders

2:45 - 3:10 pm Group picture

3:10 - 3:35 pm Sa Wang Eosinophilia: reactive, neoplastic or idiopathic

3:35 - 4:00 pm Gerald Z Gong Benign and atypical lymph node diseases

5:30 - 10:00 pm Dinner and Party at ROYAL QUEEN RESTAURANT（君豪大酒楼）

电话：718-358-3388 地址：40-21 Main St. 3/F, Flushing, NY 11355

The 4th CAPA Diagnostic Pathology Course Program (Cont’d)

Day 1, Room B

Time Speaker Title

Session 1 B Breast Session Moderators: Xinmin Zhang, Beiyun Chen

8:30 - 8:55 am Beiyun Chen Arts of writing the path report-sending the right message

8:55 - 9:20 am Hua Yang Breast stromal cell lesions

9:20 - 9:45 am Xiaoxian Li (Bill) How to manage breast papilloma?

9:45 - 10:10 am Yan Peng ASCO/CAP HER2 testing in breast cancer guidelines: 2018 focused update

10:10 - 10:30 am Break

Session 2 B GYN Session Moderators: Jianjun Wei, Pei Hui

10:30 - 10:55 am Wenxin Zheng Endometrial neoplasia: a few diagnostic points and new concepts

10:55 - 11:20 am Pei Hui Endometrial cancers and mismatch repair defi-ciency testing in clinical practice

11:20 - 11:45 am Jianjun Wei Morphological and molecular aspects of atypi-cal uterine smooth muscle tumors

11:45 - 12:10 pm Jinsong Liu Challenging issues on GYN frozen section di-agnosis

12:10 - 1:30 pm Lunch (provided by CAPA); possible promotion talk in a separate room

Session 3 B Interesting Case Session Moderators: Lizhen Gui, Minghao Zhong

1:30 - 1:45 pm Hongyu Yang (Henry) Acral Melanocytic Proliferations: Is It a Nevus or Melanoma?

1:45 - 2:00 pm Limin Yu Bitter sweet: a rash's mystery

2:00 - 2:15 pm Lanjing Zhang Think of unthinkable cases in surgical patholo-gy

2:15 - 2:30 pm Zenggang Pan Aberrant expression in lymphoma; a wolf in another wolf's clothing

2:20 - 2: 45 pm Jingmei Lin Cytomegalovirus: bystander versus pathogen

2:45 - 3:10 pm Group picture

3:10 - 3:25 pm Shaoying Li High grade B cell lymphoma: double vs. dou-ble

3:25 - 3:40 pm Yanhua Wang Did I miss one? Discovering hidden coexisting hematological and/or non-hematological neo-plasms

3:40 - 3:55 pm Qinghu Ren A case of kidney mass

Have to leave room by 4:00 pm

5:30 - 10:00 pm Dinner and Party at ROYAL QUEEN RESTAURANT（君豪大酒楼）

电话：718-358-3388 地址：40-21 Main St.3/F, Flushing, NY 11355

The 4th CAPA Diagnostic Pathology Course Program (Cont’d)

Sunday (August 26th) 7:30 am - 12:10 pm

Day 2, Room A

8:00 - 8:30 am Breakfast (provided by CAPA)

Time Speaker Title

Session 4 A GU Session Moderators: Ximing Yang, Peng Lee

8:30 - 8:55 am Miao Zhang Common challenging issues in the diagnosis of kidney cancer

8:55 - 9:20 am Steven Shen Common challenging issues in the diagnosis of testicular cancer

9:20 - 9:45 am Charles Guo Common challenging issues in the diagnosis of bladder cancer

9:45 - 10:10 am Ming Zhou Common challenging issues in the diagnosis of prostate cancer

10:10 - 10:30 am Break

Session 5 A Cytology Session Moderators: Xu Yang (Jack), Fang Fan

10:30 - 10:55 am He Wang Salivary gland lesions and Milan system

10:55 - 11:20 am Fang Fan The expected and unexpected in lung FNAs

11:20 - 11:45 am Guoping Cai FNA biopsy of thyroid lesions: it's not just all morphology

11:45 - 12:10 pm Yaxia Zhang Foreign Body in Cytology Session: Non-neoplastic Orthopedic Diseases--What We Need to Know in Real World

12:10 Adjournment and closing remarks

Day 2, Room B

Session 4 B Career Session Moderators: Beverly Wang, Jiaoti Huang

8:30 - 10:10 am Fan Lin, Fang Fan Career development with casual chatting for-mat

Beverly Wang

Feng Li, Chen Liu

Jiaoti Huang, Sang Wu

10:10 - 10:30 am Break

Session 5 B

10:30 - 11:00 am Feng Li Forensic Pathology: High profile medicolegal death investigation

11:00 - 12:10 pm Ximing Yang 怎样才能拍出好照片？--Photography skills Xiaoping Sun 好照片是拍出来的吗？-- PhotoShop

12:10 PM Adjournment and closing remarks

Progress Report of CAPA Issues (4.2018-6.2018) by Yun Gong (Approved by EC)

Weekly Online Lectures Going very well (by Linsheng Zhang and Zenggang Pan, all speakers and moderators). Annual payment for GoToWebinar ($2,200/yr) was supported by CAPA. Zenggand will be in charge of the online lectures since mid July, 2018. The 4th CAPA Diagnostic Pathology Course, Flushing, NY, Aug 25-26, 2018: • Program finalized (by Organizing Committee, Education

Committee, and all faculties) • Registration open (by Zenggang Pan, Xiangdong Xu and

other Membership/Website Committee members) • Collecting PPT, COI form, CV, and CME application (by

Lanjing Zhang) • Lectures of two classrooms will be overseen by Wei Xin

and Xiuli Liu, respectively. • Logistics ongoing (by Mark Liu, Peng Lee, Ruliang Xu,

Huihong Xu, Zenggang Pan, Zongming Chen, other EC members and CAPA members)

CAPA Co-organizes the 4th Sino-US Cancer Diagnostic Pathology Summit, Beijing, China, July 27-30, 2018 • Call-for-speakers and coordination (by Huan-You Wang).

Ten speakers with Associate professor and above were selected (this level was preferred by the organizers in China and based on the previous selecting criteria adopted by Education Committee).

• Wei Xin will attend the meeting and thus will be the team leader on behalf of CAPA.

CAP/CAPA Companion Meeting, Chicago, October 20-24, 2018 Five speakers were selected and topics were confirmed by Education Committees/Subcommittees. Wei Xin is responsible for coordination, CME application and logistics. CAPA Finance Issues • Smooth transition of finance documents from Zongming

Chen to Huihong Xu • EC reviewed and approved financial report for 2017,

prepared by Zongming • EC reviewed and approved financial balance sheets for the 1st

quarter in 2018 and those in Vancouver meeting, prepared by Huihong

• Huihong set up Money Market, on-line banking account and withdrawal account

• Internal review of CAPA finance document (bookkeeping and tax returns, etc. for the year 2015, 2016, and 2017) was started by Finance Committee, then by EC members and finally by CPA/MBA Sarah Chen with a total charge of $1000. Active communications between EC and Sarah happened in a manner of Q&A and in a 2-hr EC meeting (5.28.2018); Sarah answered EC’s questions and emphasized the necessity and urgency of change CAPA tax-exempt status to 501c. Sarah strongly suggested to dissolve current CAPA and form a new one since this strategy has much higher probability of success for 501c application than patching on the old CAPA.

• A compile report was subsequently issued by Sarah. The key messages were “The bank statements and transaction details are provided promptly by CAPA. They are clear and detailed. It appears that CAPA has been tracking business income and

expenses timely and clearly.” “In the future, we recommend use the accounting software called Quickbooks for tracking income and expenses as well as various reporting.” Sarah formatted the old CAPA Bookkeeping by using the Quickbook software during her review and Huihong will adopt this new format.

• In the future, Sarah will guide Huihong and other finance committee members to use the accounting Software and other finance-related issues.

• Due to numerous concerns about legal issues and liability of the current EC that may encountered during dissolving and reforming process, a lawyer/CAP Mr. Kent Vestal was identified and contacted. Based on EC majority vote, Yun signed a fee agreement with Mr. Vestal and he will be responsible for the entire process of dissolution of CAPA-FL and formation of CAPA-TX in order to obtain a 501c non-profit organization status.

• CAPA-TX application was filed on June 22, 2018 with 7 current EC members to be the initial BOD. A new EIN was obtained. All the 8 EC members voted “yes” for dissolving CAPA-FL. In terms of membership automatic transfer to CAPA-TX, 7 of 9 EC members voted “yes” and 2 voted “no”.

Update CAPA website (by Zenggang Pan and other Website Committee members) • All EC members agreed that there is an absolute need of

developing/improving CAPA membership administration website and we will be very cautious to ensure personal information safety.

• This website update will be handled by a US-based IT company, It will start an initial phase of test in a small group soon. The program will likely be up in one month. Any personal information of CAPA members will NOT be released to any IT or supporting companies.

• A new case forum was discussed and will not be on our priority agenda in this year due to technical issues.

CAPA eNewsletter The 1st issue was published. Call-for-submission for the 2nd issue has been sent out (Fan Chen, Xiangdong Xu, Feng Li and other eNewsletter Committee Members) Further Amendment of the Current Bylaws Bylaws Committee meetings were held 5 times to discuss amendment of the current Bylaws with good progression (Ruoqin Huang, Jay Ye, Feng Li and other committee members) Continue Fund-Raising Campaign • AccuPath $2,000 (15-30 min talk during lunch time):

initiated by Peng Lee • Novodiax $2,000 (booth): initiated by Fan Lin, Songqing

Zhao • Merrill Lynch (pending further information): initiated by

Zenggang Pan • ACAP (pending further information): initiated by Ruliang Xu Four EC meetings (refer to previously released 4 minutes that were recorded by Xiuli Liu and Zenggang Pan, reviewed by all EC members and approved by majority of EC members)

Recent Achievements from CAPA Members

Achievements and awards:

1. Dr. Xiaoxian Li was promoted to associate professor of Pathology (starting 9/1/2018), Emory Uni-versity, Atlanta GA

2. Dr. Xiaoxian Li was selected to serve on ACS grant review committee.

3. Dr. Yan Peng, has been promoted to Professor of Pathology at the University of Texas Southwest-ern Medical Center at Dallas.

Grants:

Wang H (PI): Candidate therapeutic targets & pathways in cardiac tissues from normal healthy control & heart failure subjects

Funding Agency: Bristol Myers Squibb Pharmaceutical Co

Funding amount & period: $160,000/year; 7/2018-6/2019 renewable

Courses and invited lectures:

1. Dr. He Wang, Milan system of Salivary gland cytopathology: Recent progress and case discussion. 16th Annual Chinese Cytopathology meeting. Changsha, China (June 14-16, 2018)

2. Dr. He Wang, Hot topic: Salivary gland cytopathology: Milan system and More. Webinar Presen-tation for American Society of Cytopathology. February 2018

3. Dr. Xiaohua Qian, Invited speaker at the 41st European Congress of Cytology. Soft Tissue Cyto-pathology Symposium, Madrid, Spain (June 10-13, 2018)

Books and book chapters:

1. Huang Q. Ed. “Gastric Cardiac Cancer”. Springer International Publishing. 2018

2. Rossi ED, Ali S, Chandra A, Field A, Gong Y, Maleki Z, Ping B, Wang H: Chapter 6: Suspicious for malignancy. In: Milan System of Salivary gland Classification 1st edition, Editor: Faquin W and Rossi DE. Springer Science and Business Media, Philadelphia, PA 19106; 2018

3. Barkan GA, Vielh P, Pambuccian S, Wojcik EM, Mehrotra S, Wang H, Al-Abbadi MA. Chapter 7: Positive for malignancy. In: Milan System of Salivary gland Classification 1st edition, Editor: Faquin W and Rossi DE. Springer Science and Business Media, Philadelphia, PA 19106; 2018

4. Wang H, Malik A, Gong Y. Chapter 1: Salivary gland FNA. In: Atlas of Non-GYN Cytopatholo-gy.1st edition, Editor: Jing X, Siddiqui A, Li K. Springer Science and Business Media, Philadelph-ia, PA 19106; 2018

Recent Achievements from CAPA Members

Recent Publications from CAPA Members

1. Gong S, Crane GM, McCall CM, Xiao W, Ganapathi KA, Cuka N, Davies-Hill T, Xi L, Raffeld M, Pittaluga S, Duffield AS, Jaffe ES. Expanding the Spectrum of EBV-positive Marginal Zone Lymphomas: A Lesion Associated With Diverse Immunodeficiency Settings. American Journal of Surgical Pathology. 2018 Jun 27. [Epub ahead of print].

2. Huang Q, Cheng YQ, Chen L, Du MZ, Wang YH, Xu GF, Shi J, Fan XS, Zhou XL, Zhang YF, Guo LC, Liu TY, Zhou D, Mashimo H, Gold JS, Zou XP, and Jiangsu Province Early Gastric Carcinoma Multicenter Study Team. Low risk of lymph node metastasis in 495 early gastric cardiac carcinomas: A multicenter clinicopathologic study of 2101 radical gastrectomies for ear-ly gastric carcinoma. Mod Pathol. 2018 May 25. doi: 10.1038/s41379-018-0063-1. [Epub ahead of print]

3. Pu X, Zhu L, Fu Y, Fan Z, Zheng J, Zhang B, Yang J, Guan W, Wu H, Ye Q, Huang Q. Com-panied P16 genetic and protein status together providing useful information on the clinical out-come of urinary bladder cancer. Medicine (Baltimore). 2018 Apr;97(15):e0353.

4. Schaefer I, Fletcher JA, Nielsen GP, Shih AR, Ferrone ML, Hornick JL, Qian X. Immunohisto-chemistry for Histone H3G34W and H3K36M is Highly Specific for Giant Cell Tumor of Bone and Chondroblastoma, Respectively, in Fine Needle Aspiration and Core Needle Biopsy. Can-cer Cytopathol. 2018 May 14. doi: 10.1002/cncy.22000

5. Ren S, Klump W. Gynecologic Serous Carcinoma: An Immunohistochemical Analysis of Ma-lignant Body Fluid Specimens. Arch Pathol Lab Med. 2018 Apr 24. doi: 10.5858/arpa.2017-0260-OA. [Epub ahead of print]

6. Luo X, Jhala N, Khurana JS, Fundakowski, C; Jhala DN, Wang H. Moving Toward a Systemat-ic Approach for Reporting Salivary Gland Cytopathology: An Institutional Experience and Lit-erature Review. Arch Pathol Lab Med. 2018 accepted.

7. O'Conor CJ, Chen T, Gonzalez l, Cao D, and Yan Peng. Cancer Stem Cells in Triple Negative Breast Cancer: A Potential Target and Prognostic Marker. Biomarkers in Medicine, 2018 Jun 15. doi:10.2217/bmm-2017-0398. [Epub ahead of print].

Report to CAPA eNewsletter

Professors Lanjing Zhang and Jiaoti Huang co-organized the Fifth Princeton Integrated Pathology Symposium (PIPS V): Urologic Pathology, which took place at Princeton Medical Center, Plains-

boro, NJ, on April 15, 2018. The meeting attracted more than 250 attendees. Many CAPA members participated the event as a speaker (Drs. Liang Cheng, Ximing Yang and Chin-Lee Wu, in alphabet-ical order), volunteer or attendee. The co-chairs both are CAPA members and former executive

committee members, and would like to thank CAPA members for their support. The next PIPS will be focused on gastrointestinal pathology, and take place on Sunday April 7, 2019.

Case of Quarter (COQ) for CAPA eNewsletter (V3 I3)

Submitted by Henry Yang

Part 1.

This is a 45 year old lady with cervixal cancer

1.5 years ago. And now underwent chemotherapy

and radiation treatment. the plague is indurated

and not painful.

Part 2. Lower Back Lesion

Part 2. H&E

Part 3.

Diagnosis: Hobnail Hemangioma or Targetoid Hemosiderotic Hemangioma This is a benign vascular neoplasm most commonly

occurring on the trunk or extremities of young to

middle-aged adults. Clinically, this lesion often

presents as a solitary purple papule surrounded by a

pale halo and occasionally by a peripheral ring. What

we saw here in the images provided, is an

“infiltrating” vascular neoplasm occupying the whole

dermis. In the superficial dermis, an irregular,

dilated, thin-walled proliferation of vascular channels

is lined by prominent, often hobnail endothelial cells

with occasional papillary projections. Extravasated

red blood cells and inflammatory cells may be seen in

the surrounding stroma. In the deeper component, the

vascular channels become narrowed, they dissect the

collagen, and they are lined by flat endothelial cells.

The lesion appears to be self-limited, and an excision

is curative. The differential diagnosis includes

microvenular hemangioma, and Kaposi sarcoma.

Microvenular hemangioma normally shows elongated

vessels with narrow “compressed “ lumina that

display interconnections and branching configurations

that may extend into subcutaneous septa. These

vessels have venous characteristics. Despite this

somewhat unusual configuration, this kind of lesion

appears to be relatively confined on low-power

inspection, shows minimal if any inflammation, and

lacks nuclear atypia or mitotic activity.

Kaposi sarcoma is a malignant vascular neoplasm

which will show typical findings such as the

“promontory sign,” hyaline globules, plasma cells,

and solid aggregates of spindled cells, which are not

observed in the presented case. ( case courtesy: Dr

Hongxiao Chen, Department of Dermtology,Linyi

people’s Hospital, Linyi, Shandong, China)

Case of Quarter (COQ) for CAPA eNewsletter

Submitted by John Cai, MD. staff dermatopathologist, and subspecialty medical

director of dermatopathology, Dianon Systems, Florida division

Part 1.

A 67 years-old male presented with a dark papule

on his left temple. Dermatologist wanted to rule

out pigmented basal cell carcinoma versus

melanoma.

Part 2. H&E

What is your differential diagnosis and

further work-up?

Recipes of Quarter (ROQ) for CAPA eNewsletter

Submitted by Dan Lu

Dry-Aged Roasted Prime Ribs

Use USDA prime (or USDA choice) prime ribs, 6-8 lb. open the wrap, lay on a rack and leave in

refrigerator for 3-5 days. On the day of serving, take out from the fridge,

leave in room temperature for 2 hrs. Trim off the dried meat on the surface. Rub surface with cooking oil first, then fresh garlic, salt, pepper,

rosemary, etc.

Start to roast at 11 am, 170F for 6-7 hrs, on a rack, not wrapped (insert thermometer: 150F or

less).

Take out from the oven and wrap in foil. Settle for 10 minutes and then slice to serve (warm up

the plates). Sprinkle with salt and pepper and eat with horse radish (get from grocery stores) .

\

Enjoy immediately while is hot, with red wine.

Accupath Laboratories, Inc.

NovoDiax, Inc.

NewPath Diagnostics

EastGene Laboratories

Webpathlab, Inc

Dr. Peng Lee

Dr. Yingxian (Mark) Liu