cheminform abstract: synthesis of 3,3-diindolyl oxyindoles efficiently catalyzed by fecl3 and their...

ChemInform 2011, 42, issue 03 © 2011 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim Indole derivatives R 0140 DOI: 10.1002/chin.201103116 Synthesis of 3,3-Diindolyl Oxyindoles Efficiently Catalyzed by FeCl 3 and Their in vitro Evaluation for Anticancer Activity. — Compound (IIIb) exhibits potent cytotoxicity against SK-N-SH and DU-145 human cancer cell lines, whereas compounds (IIIc)—(IIIe) and (Vc) exhibit potent cytotoxicity against the DU-145 cell line. — (KAMAL*, A.; SRIKANTH, Y. V. V.; KHAN, M. N. A.; SHAIK, T. B.; ASHRAF, M.; Bioorg. Med. Chem. Lett. 20 (2010) 17, 5229-5231, http://dx.doi.org/10.1016/j.bmcl.2010.06.152 ; Org. Chem. Div., Indian Inst. Chem. Technol., Hyderabad 500 607, India; Eng.) — K. Woydowski 03- 116

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Page 1: ChemInform Abstract: Synthesis of 3,3-Diindolyl Oxyindoles Efficiently Catalyzed by FeCl3 and Their in vitro Evaluation for Anticancer Activity

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Indole derivativesR 0140 DOI: 10.1002/chin.201103116

Synthesis of 3,3-Diindolyl Oxyindoles Efficiently Catalyzed by FeCl3 and Their in vitro Evaluation for Anticancer Activity. — Compound (IIIb) exhibits potent cyto-toxicity against SK-N-SH and DU-145 human cancer cell lines, whereas compounds (IIIc)—(IIIe) and (Vc) exhibit potent cytotoxicity against the DU-145 cell line. — (KAMAL*, A.; SRIKANTH, Y. V. V.; KHAN, M. N. A.; SHAIK, T. B.; ASHRAF, M.; Bioorg. Med. Chem. Lett. 20 (2010) 17, 5229-5231, http://dx.doi.org/10.1016/j.bmcl.2010.06.152 ; Org. Chem. Div., Indian Inst. Chem. Technol., Hyderabad 500 607, India; Eng.) — K. Woydowski

03- 116

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