circadian rhythms
DESCRIPTION
Circadian rhythms also known as "The Body Clock" is the physical, mental and behavioral changes that follow roughly 24 hrs. cycle responding to light and darkness in the organism.TRANSCRIPT
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Circadian rhythms
&
Human health
Presented by Dr. Sudhakar KokateDirector PPRC, India
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Circadian rhythms .…
Also known as the “Body clock”
Physical, mental and behavioural changes that
follow a roughly 24 hrs. cycle responding to light
and darkness in the organism
Found in living things, plants, animals and even
among tiny microbesPPRC/INDIA 01
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Circadian rhythms .…
PPRC/INDIA 02
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Circadian rhythms ….
Related to biological cycle
Study of Circadian rhythms and health is known
as “Chronobiology”
Biological cycle controls Circadian rhythms –
governing of interacting molecules in cells
throughout the bodyPPRC/INDIA 03
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Master clock ….
Master clock: Brain
A group of nerve cells ‘Suprachiasmatic nucleus’
(SCN) containing 20,000 nerve cells are located
in hypothalamus
Location: above optic nerves from eyes cross
PPRC/INDIA 04
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Brain
PPRC/INDIA 05
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Suprachiasmatic nucleus
PPRC/INDIA 06
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About CR ….
Circadian rhythms influence sleep wake cycles,
hormone release and other bodily functions
CR – linked to sleep disorders e.g. Insomnia,
Obesity, Diabetes, Depression, Bipolar disorders
and Seasonal Affective Disorder (SAD)
PPRC/INDIA 07
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Insomnia
PPRC/INDIA 08
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Obesity
PPRC/INDIA 09
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Diabetes
PPRC/INDIA 10
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Depression
PPRC/INDIA 11
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Bipolar disorders
PPRC/INDIA 12
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Seasonal Affective Disorder (SAD)
PPRC/INDIA 13
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About CR ….
CR tells our body when to sleep and regulate
many other physiological processes
This internal body clock is affected by
environmental cues like sunlight and
temperature
When CR is disrupted, sleeping & eating
patterns can run amokPPRC/INDIA 14
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Physiological disruption leads to ….
PPRC/INDIA 15
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Research ….
A growing body of research is examining the
adverse health effects like increasing cardio-
vascular events, observing neurological problems
like depression and bipolar disorders.
It also affects immune and metabolic systems
PPRC/INDIA 16
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Immune system
PPRC/INDIA 17
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Metabolic system
PPRC/INDIA 18
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Research ….
Scientists are looking into:
1. How brain-neuro system works in disorder?
2. What are effective remedies without side effects
with minimum duration of time span?
3. Behaviour of Human being in disrupted CR
positionPPRC/INDIA 19
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Research ….
4. Treatment of sleep disorders, Jet lag and other
health related issues
5. Do Ayurvedic plants control Circadian rhythms
in plants, animals and microbes? If so how and
at what level of output?
PPRC/INDIA 20
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Research ….
6. Are there any natural control for strengthening
nerves and muscle? If so how and what
mechanism does it possess?
PPRC/INDIA 21
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Remedies ….
Change or modify lifestyle
Ideal diet plan – implementation
Yoga, exercises and meditation
Use of herbal technology
Well disciplinary actions in exact time
Strengthen and calm – nerves and musclesPPRC/INDIA 22
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Yoga
PPRC/INDIA 23
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Exercise
PPRC/INDIA 24
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Meditation
PPRC/INDIA 25
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Cryobiology
Study of cell preservation technology with low
temperature
Applied science
Rule: Every 10°C reduction in temperature
= 50 % decrease in oxygen consumption
PPRC/INDIA 26
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Cryobiology
Temperature ranges 32 to 37°C
and -80 to -196°C
Many Journals, Societies study Cryobiology
PPRC/INDIA 27
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Neurochemicals ….
Organic molecules participating in Neural activity
Neuropeptide: Oxytocin signifies maternal
behaviour, stress wound healing
Glutamate
GABA: Inhibits neurotransmission
PPRC/INDIA 28
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Neurochemicals
PPRC/INDIA 29
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Neuropeptide
PPRC/INDIA 30
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Oxytocin
PPRC/INDIA 31
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Glutamate
PPRC/INDIA 32
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GABA
PPRC/INDIA 33
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Neurochemicals ….
Organic molecules participating in Neural activity
Dopamine: Function of the limbic system,
emotional function and control
Serotonin: Mood, sleep and alertness, sensation
of pleasure
PPRC/INDIA 34
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Dopamine
PPRC/INDIA 35
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Serotonin
PPRC/INDIA 36
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Neurochemicals ….
Organic molecules participating in Neural activity
Acetylcholine: Memory
Nitric oxide
Endocannabinoids: Eicosanoids
PPRC/INDIA 37
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Acetylcholine
PPRC/INDIA 38
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Nitric oxide
PPRC/INDIA 39
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Endocannabinoids
PPRC/INDIA 40
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Foods for healthy nerves ….
₪ Milk
₪ Yogurt
₪ Honey
₪ Apple
₪ Mangoes
PPRC/INDIA 41
₪ Potatoes
₪ Bananas
₪ Herbal tea
₪ Whole grain
₪ Sweet potatoes
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Foods for healthy nerves ….
PPRC/INDIA 42
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Foods for healthy nerves ….
₪ Pineapples
₪ Beet salad
₪ Grape fruits
₪ Oranges
₪ Almonds
PPRC/INDIA 43
₪ Green salad
₪ Dates
₪ Cashew nuts
₪ Coconut water
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PPRC/INDIA 44
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₪ Tulsi
₪ Sunflower
₪ Papaya
₪ Peppermint
PPRC/INDIA 45
₪ Avocado
₪ Cabbage
₪ Cauliflower
₪ Asparagus
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Tulsi (Ocimum sanctum)
PPRC/INDIA 46
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Sunflower
PPRC/INDIA 47
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Papaya
PPRC/INDIA 48
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Peppermint
PPRC/INDIA 49
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Avocado
PPRC/INDIA 50
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Cabbage
PPRC/INDIA 51
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Cauliflower
PPRC/INDIA 52
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Asparagus
PPRC/INDIA 53
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₪ Alfalfa
₪ Parsley
₪ Garlic
₪ Beet
PPRC/INDIA 54
₪ Kale
₪ Hemp
₪ Fenugreek
₪ Lime
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Alfalfa
PPRC/INDIA 55
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Parsley
PPRC/INDIA 56
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Garlic
PPRC/INDIA 57
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Beet
PPRC/INDIA 58
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Kale
PPRC/INDIA 59
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Hemp
PPRC/INDIA 60
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Fenugreek
PPRC/INDIA 61
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Lime
PPRC/INDIA 62
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