clase fosforilación oxidativa [modo de compatibilidad] · 2019. 5. 7. · 0.816 0.771 0.421...
TRANSCRIPT
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Fosforilación oxidativa y fotofosforilación
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Teoría quimiosmótica aplicada a la mitocondria
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Nucleótidos de nicotinamida
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Nucleótidos de flavina
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Ubiquinona o CoQ
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Citocromos
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Citocromos
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Proteínas ferrosulfuradas
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Complejo I
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Proceso en Complejo I
NADH + 5 H+N + Q NAD+ + 4H+
P + H2Q
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Complejo II
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Proceso en Complejo II
Succinato + Q Fumarato+ H2Q
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Complejo III
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Complejo III
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Complejo IV
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Proceso en Complejo IV
4 Cit cred + 8 H+N + O2 4 Cit cox + 4 H+
P + 2 H2O
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Proceso global en la cadena respiratoria
NADH + H+ + ½ O2 NAD+ + H2O
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Balance de la fosforilación oxidativa
NADH + H+ (Succinato)+ ½ O2 + x ADP + x Pi NAD+ (Fumarato) + H2O+ x ATP
x = P/O = P/2e-
Por cada 4 H+ = 1 ATP
Por cada NADH se bombean 10 H+ = 2.5 ATP (P/O) = 2.5
Por cada FADH2 se bombean 6 H+ = 1.5 ATP (P/O) = 1.5
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