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B5.,#>=7.1,#252/3/53.20#>=.#56,#4.,20#06#09#/0</=M#P(6#09#B.5>=#70#02/573=#70

No. totalde pacientes

No. de infecciones

Promedio de días en el hospital

6056

14

6

40

20

U3=&0")*_)C5231.523")1.)356.223(5./)2(5%0"$1"/).5).')B(/#3%"')U&0737,#,8,@90806/0#>=.#(.r36#i"#+02209V

U[ ><1$(,)-8/?/8(@(#*?0/-'8(.8'?'A$)(-/,%.:9/-$)

_o#>,-306/02#?50#02/5H30.=6#K=2>3/,93F,7=2#56#>.=8073=#70#]n#71,2E#o#-=6C/.,\0.=6#3640--3=602Q"N&5L67=#20#\52/343-,#56,#3952/.,-3:6O#`=#K,A#.0B9,2#-9,.,2E#>0.=#>=70C

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!&[51()&%3'3I"0 =0[632"/

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(2/.0>/=83-36, _ ]k ]_ mkD2=63,F37, g ]m ]_ ]_(2/.0>/=83-36,#v#32=63,F37, jk ok gk ]kk, +=2#>,-306/02#,K=.,#6=#/,6#>,-306/02E#20#K,6#702-.3/=#06#56#/.,@,\=#,6/0.3=.#Uo]V"@ +,#80\=.#-,937,7#20#=@/3060#70#6502/.=#>.=H007=.#Ui,.8,-3,#709#I50@9=E#I=@9,-K=E#+[V"

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!4;()#0.#"0"0 =0[632"/

(6#,6/0.3=.02#073-3=602#70#02/0#93@.=E#7,@,#=.306/,-3=602#-=6-.0/,2#[email protected]:8=#5/393F,.#>,>09#-5,7.3-59,7=E#/36/,#-K36,E#232/08,2#70#.=/59,7=E#0/-"#R5C.,6/0#B060.,-3=602E#9,2#B.L43-,2#20#K,6#>.0>,.,7=#-=6#02=2#8,/0.3,902#A#5/3C93F,67=#02,2#/;-63-,2"W=AE#236#08@,.B=E#H3H38=2#06#56#8567=#.0H=95-3=6,7=#>=.#9,2#-=8C

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Duración del tratamiento(semanas)

Culti

vos

nega

tivos

(%)

100

80

60

40

20

0 2 4 6 8

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Espermidina (mg/ml)

% d

el te

stig

o

300

200

100

0 ,20 ,40 ,60 ,80 1,00

><1$(#8,#'8'8(/0*).8'-/$%,)(b./0,)(((UJ

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R";":()Q)13/#(/32345)1.)'"/)=0[632"/

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10105

106

107

108

20 40 60 mg/ml

Dosis Área bajo la curva de concentración total en sangre Área bajo la curva logarítmica de concentración

Núm

ero

de b

acte

rias

viab

les/

mus

lo

Cefazolina

Cefradina

200105

106

107

108

400 800 1000 mg/m x min

Cefazolina

Cefradina

-100105

106

107

108

0 200 300100

Cefazolina

Cefradina

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Punto 2

Punto 3

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