curriculum vitae 09
TRANSCRIPT
Curriculum Vitae of
KARL DANIEL SKALA5201 Gasconade Drive
Columbia, Missouri 65202(573) 474-2195
E-mail: [email protected]
EDUCATIONFORMAL :
University of Missouri, Columbia, MO M. A. degree in Psychology (Experimental - 86 graduate hours) ………………….……..……1986
Massachusetts Institute of Technology, Cambridge, MA Certification in Biomechanics of Human Movement ……………...…………………………..1984
Southern Illinois University, Carbondale, ILB. A. degree in Psychology (Biology minor)..………………………………………...…......…1977
TECHNICAL :U. S. Marine Corps Communications & Electronics School, San Diego, CA
Graduate of Electronics & Aviation Radar Repair Program ……………………...………....…1967
PROFESSIONAL SKILLS
Administrative:Core Director, laboratory manager, personnel supervisor, procurement, purchasing & inventory
Biomechanics: Movement analysis system (Selspot®); kinematics
Cardiovascular:Cardiovascular researches; Coronary stent research; Cardiac cannulation & ultrasound (swine), micro-vascular cannulation (mouse); diabetes & hypertension studies (swine & rodent)
Computer Applications:PC® & Macintosh® platforms; Integrated office (MS Office®); Statistical & graphic analyses; Image processing (ImagePro® & Adobe Photoshop®)
Electronics: Audio, video, test equipment utilization, maintenance & repair
Experimental Design:Design, strategy, control, analysis, & critical evaluation; hypothesis testing
Histology:Necropsy & perfusion; tissue preparation & dissection, frozen and paraffin sectioning & staining
Mechanical:Mechanical drawing, design & fabrication of experimental apparatus
Neuroscience:Brain integrity, dysfunction & recovery; Stereotaxic central cannulae preparations (primate & rodent); cortical ablation & electrolytic lesion
Supervisory:Military, research/technical staff & student
Statistics:Descriptive & inferential (SAS, SPSS & SigmaStat); parametric & nonparametric
Teaching:Teaching & tutoring; interviews, psychometrics & testing; public presentations & reports
Technical:Behavioral & kinesiological measurement; physiological (EEG, EMG & EKG), radio telemetry; immunohistochemistry & radioimmunoassay; 2D & 3D image processing; bright field & confocal fluorescence microscopy
Writing:
Manuscripts, proposals, research/animal care & use protocols, reports, summaries, & reviews
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PROFESSIONAL EXPERIENCE
RESEARCH :Psychopharmacology:
Southern Illinois University-Carbondale ................................................................................... 1976Comparative models of neurological recovery;Undergraduate Research Assistant to Dr. L. Baez
Neuropsychology of Primates: Southern Illinois University-Carbondale ............................................................................. 1976-79Comparative models of learning & memory;Graduate Research Assistant to Dr. D. K. Bliss
Atomic & Molecular Physics: University of Illinois-Chicago .............................................................................................. 1979-80LASER systems applications & development; optics;Assistant Research Engineer for Dr. C. K. Rhodes
Behavioral Toxicology: University of Missouri-Columbia ........................................................................................ 1981-83Behavioral assessments of exposure to methyl-mercuric chloride;Graduate Research Assistant to Dr. D. C. Wright & Dr. V. St. Omer
Human Infant Development:University of Missouri-Columbia ........................................................................................ 1983-85Infant motor development & interlimb coordination;Graduate Research Assistant to Dr. E. Thelen
Physiological Psychology: University of Missouri-Columbia ........................................................................................ 1984-86Comparative models of learning & memory; neurological recovery;Graduate Research Assistant to Dr. D. C. Wright
Department of Neurology: University of Missouri-Columbia School of Medicine ...............................................................1987Researches of Myasthenia gravis;Graduate Research Assistant to Dr. J. D. Dexter
Human Learning: University of Missouri-Columbia ........................................................................................ 1988-89Brain lateralization; visual split field techniques;Graduate Research Assistant to Dr. J. H. Mueller
Behavioral Toxicology: Lincoln University-Jefferson City ....................................................................................... 1989-90Behavioral & morphological researches with the artificial sweetener, Aspartame; Biomedical researcher for Dr. R. H. Hancock
Neuroendocrinology: University of Missouri-Columbia School of Medicine ........................................................ 1990-92Hypothalamic-pituitary unit researches; Atrial natriuretic peptides; Biomedical researcher for Dr. W. K. Samson
Department of Obstetrics & Gynecology & Veterinary Biomedical Sciences:University of Missouri-Columbia Schools of Medicine & Veterinary Medicine …………. 1992-94Development of an in vitro model for uterine drug screening;Biomedical researcher for Dr. S. W. Snyder
Department of Internal Medicine - Cardiology: University of Missouri-Columbia School of Medicine ........................................................ 1994-96Vascular Endothelium researches; Microvascular researches; CanineStent Research Project Coordinator/Cordis Corp.Biomedical researcher for Dr. P. R. Myers & Dr. R. Webel
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PROFESSIONAL EXPERIENCE continued
RESEARCH cont .: Dalton Cardiovascular Research Center:
University of Missouri-Columbia Vascular Biology Laboratory ..............………............... 1996-00Two & Three dimensional imaging; Confocal fluorescence microscopy;Cardiovascular Surgery (swine); Swine model of DiabetesLaboratory Manager & Senior Biomedical Researcher for Dr. M. Sturek
Dalton Cardiovascular Research Center:University of Missouri-Columbia Cardiovascular Neurobiology Laboratory .................. 2001-2005Laboratory Manager, Cardio-microvascular & central stereotaxic surgery;Immunohistochemistry; Imaging; Confocal fluorescence microscopyAnimal models for Hypertension & Barorecepter Regulation (rodent)Laboratory Manager & Senior Biomedical Researcher for Dr. M. Hay
Department of Veterinary Medicine & Biological Sciences:University of Missouri-Columbia School of Veterinary Medicine .................................. 2005-2008Director, Swine Hormone Research Core; Cardiovascular Metabolism Laboratory, ManagerImmunohistochemistry; Imaging; Confocal fluorescence microscopy; AutosamplingAnimal models for Vascular Metabolism & Cardiovascular Regulation (swine & rodent)Laboratory Manager & Senior Associate for Dr. L. Rubin
TEACHING :Experimental Physiological Psychology:
Southern Illinois University-Carbondale ................................................................................... 1976Neurosurgical techniques;Undergraduate Teaching Assistant to Dr. R. Wilcox
Behavioral Sciences: Southern Illinois University-Carbondale School of Medicine ....................…...................... 1977-78Tutoring & course evaluation;Graduate Teaching Assistant to Dr. D. K. Bliss
Comparative & Physiological Psychology: University of Missouri-Columbia .............................................................................................. 1980Lecture & course evaluation;Graduate Teaching Assistant to Dr. D. C. Wright
Experimental Psychology: University of Missouri-Columbia ......................................................................................... 1985-86Lecture, demonstration, & equipment maintenance;Graduate Teaching Assistant to Dr. R. Wright
Human Learning:University of Missouri-Columbia ......................................................................................... 1988-89Brain lateralization; visual split field techniques;Graduate Teaching Assistant to Dr. J. H. Mueller
Research Group Staff Certification: Lincoln University-Jefferson City .............................................................................................. 1989Specialized laboratory animal procedures series: presentation & demonstration;Guest lecturer invited by Dr. S. Meredith
PERSONAL DATA
FAMILY : Married with three childrenHEALTH : ExcellentVETERAN : U. S. Marine Corps (Vietnam Era), Honorable Discharge (1972), Sergeant (E5)VOLUNTEER : City Councilman, Columbia MO (2007-now)
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BIBLIOGRAPHY
Modrow, H. E., Petroff, R. J., Skala, K. D., and Bliss, D. K. (1977). Effects of amygdala lesions on state dependent learning and transfer. Paper presented at the meeting of the Eastern Psychological Association, Boston.
Modrow, H. E., Skala, K. D., and Bliss, D. K. (1977). Effects of cortical ablations on transfer in a state dependent learning paradigm. Bulletin of the Psychonomic Society, 10, 255.
Skala, K. D., Modrow, H. E., and Bliss, D. K. (1977). Effects of small thalamic (centrum medianum) lesions on state dependent learning and transfer. Bulletin of the Psychonomic Society, 10, 255.
Modrow, H. E., Skala, K., and Bliss, D. K. (1978). Physiological substrates of state dependent learning. Psychopharmacology, 58, 8.
Modrow, H. E., Skala, K., Petroff, R., and Bliss, D. K. (1978). Physiological substrates of state dependent learning. In F. C. Colpaert and J. A. Rosecrans (Eds.), Stimulus Properties of Drugs: Ten Years of Progress (pp. 415-421). Amsterdam: Elsevier/North-Holland Biomedical Press.
Skala, K. D., Fisher, D. M., and Thelen, E. (1984). Kinematic analysis of infant kicking: Weight gain as a non-neurological factor in interlimb coordination. Paper presented at the Annual Research & Creative Activities Forum, University of Missouri, Columbia.
Skala, K. D. (1986). Interoperative visual experience and the serial lesion effect. M. A. Thesis, University of Missouri, Columbia.
Wright, D. C., Skala, K. D., and Peuser, K. A. ((1986). Latent inhibition from context-dependent retrieval of conflicting information. Bulletin of the Psychonomic Society, 24, 152-154.
Thelen, E., Skala, K. D., and Kelso, J. A. S. (1987). The dynamic nature of early coordination: Evidence from bilateral leg movements in young infants. Developmental Psychology, 23(2), 179-186.
Wright, D. C., Skala, K. D., and Cloud, M. D. (1987). Does "multiple encoding" produce the serial lesion effect? Paper presented at the meeting of the Midwestern Psychological Association, Chicago.
Skala, K. D., and Wright, D. C. (1987). Multiple state training protects old memories retrieved following brain damage. Paper presented at the Annual Research & Creative Activities Forum, University of Missouri, Columbia.
Wright, D. C., Cloud, M. D., and Skala, K. D. (1988). State dependent retrieval and the serial lesion effect. Paper presented at the meeting of the Psychonomic Society, Chicago.
Samson, W. K., Skala, K. D., Alexander, B., and Huang, F.-L. S. (1990). Pituitary site of action of endothelin: selective inhibition of prolactin release in vitro. Biochemical and Biophysical Research Communications, 169(2), 737-743.
Samson, W. K., Skala, K., Huang, F.-L. S., Gluntz, S., Alexander, B., and Gomez-Sanchez, C. E. (1991). Central nervous system action of endothelin-3 to inhibit water drinking in the rat. Brain Research, 539, 347-351.
Samson, W. K., Skala, K. D., Alexander, B., and Huang, F.-L. S. (1991). Possible neuroendocrine actions of endothelin-3. Endocrinology, 128, 1465-1473.
Samson, W. K., Skala, K. D., Alexander, B., and Huang, F.-L. S. (1991). Hypothalamic endothelin: presence and effects related to fluid and electrolyte homeostasis. Journal of Cardiovascular Pharmacology, 17(S7), 345-348.
Samson, W. K., Alexander, B. D., Skala, K. D., Huang, F.-L. S., and Fulton, R. J. (1991). Central peptidergic mechanisms controlling reproductive hormone secretion: a novel methodology reveals the role of the natriuretic peptides. Canadian Journal of Physiology and Pharmacology, 70(5), 773-778.
Samson, W. K., Skala, K. D., and Huang, F.-L. S. (1991). CNP-22 stimulates, rather than inhibits, water drinking in the rat: evidence for a unique biological action of the c-type natriuretic peptides. Brain Research, 568, 285-288.
Samson, W. K., Skala, K. D., and Huang, F.-L. S. (1991). Hypothalamic endothelin: presence and site of action. FASEB Journal 5(5), 1147.
Samson, W. K., Alexander, B. D., Skala, K. D., Huang, F.-L. S., and Fulton, R. J. (1992). Oxytocin-ricin cytotoxin conjugate administration reveals a physiologically relevant role for oxytocin in the control of gonadotropin secretion. Annals of the New York Academy of Sciences, 652, 411-422.
Samson, W. K., Skala, K. D., Huang, F.-L. S., Alexander, B. D., and Gomez-Sanchez, C. E. (1992). A prolactin release inhibiting activity isolated from neurointermediate lobe extracts is an endothelin-like peptide. Regulatory Peptides, 39(1), 103-112.
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BIBLIOGRAPHY continuation
Samson, W. K., and Skala, K. D. (1992). Comparison of the pituitary effects of the mammalian endothelins: vasoactive intestinal contractor (endothelin-beta, rat endothelin-2) is the most potent inhibitor of prolactin secretion. Endocrinology, 130(5), 2964-2970.
Huang, F. -L., Skala, K. D., Samson, W. K. (1992). Hypothalamic effects of c-type natriuretic peptide (CNP) on luteinizing hormone secretion. Journal of Neuroendocrinology, 4(3), 325-330.
Huang, F. -L., Skala, K. D., Samson, W. K. (1992). C-type natriuretic peptide stimulates prolactin secretion by a hypothalamic site of action. Journal of Neuroendocrinology, 4(5), 593-597.
Snyder, S. W., Skala, K. D., Adams, H. A., and Sturek, M. S. (1994). The selective effects of platelet activating factor, tumor necrosis factor and prostaglandin F2aon pregnant rat uterine contractility in vitro. Life Sciences.
Dietz, N. J., Skala, K., and Sturek, M. (1996). Localized Ca2+ release from the sarcoplasmic reticulum of coronary smooth muscle cells resolved with video rate imaging. Paper presented at the International Meeting of Vascular Biology, Seattle, Washington.
Dietz, N. J., Skala, K., and Sturek, M. (1997). Localized Ca2+ release from the sarcoplasmic reticulum of coronary smooth muscle cells resolved with video rate imaging and laser scanning confocal microscopy. Abstract and poster presentation for Cardiovascular Day, University of Missouri, Columbia.
Skala, K., Voelker, D. J., Reddy, H. K., and Sturek, M. (1997). Three-dimensional reconstruction of intravascular ultrasound images from human coronary arteries. Abstract and poster presentation for Cardiovascular Day, University of Missouri, Columbia.
Skala, K., Dietz, N, J., and Sturek, M. (1998). Interdisciplinary Diabetes and Cardiovascular Research. Video poster presentation for Cardiovascular Day, University of Missouri, Columbia.Otis, C. R., Wamhoff, B. R., Skala K., and Sturek, M. (1999). Hyperlipidemia decreases insulin
sensitivity in diabetic swine. Abstract and poster presentation for Cardiovascular Day. University of Missouri, Columbia. Abstract and poster presentation for Cardiovascular Day, University of Missouri, Columbia.
Otis, C. R., Wamhoff, B. R., Provencher, I., Arnsmeyer, J., Pineda, Skala K., and Sturek, M. (1999).Insulin sensitivity testing in Yucatan swine. Abstract and poster presentation for the 34th Annual Midwest Regional AALAS Meeting, Mid-Missouri Branch of the American Association for Laboratory Animal Science, Columbia, Missouri.
Pineda, J., Wamhoff, B. R., Otis, C., Provencher, I., Arnsmeyer, J., Skala, K., and Sturek, M. (1999).Diabetic Yucatan Swine: maintenance of hyperglycemia and body weight. Abstract and poster presentation for the 34th Annual Midwest Regional AALAS Meeting, Mid-Missouri Branch of the American Association for Laboratory Animal Science, Columbia, Missouri.
Skala, K., Wamhoff, B. R., Otis, C., Provencher, I., Arnsmeyer, J., Pineda, and Sturek, M. (1999). Vascular access port implantation in diabetic miniature swine: complications and outcomes. Abstract and poster presentation for the 34th Annual Midwest Regional AALAS Meeting, Mid-Missouri Branch of the American Association for Laboratory Animal Science, Columbia, Missouri.
Sturek, M., Reddy, H. K., Voelker, D. J., Skala, K., Wamhoff, B. R., Humphrey, C. D., Luis-Fuentes, V., and Bonagura, J. (1999). Coronary angiography and intravascular ultrasound procedures in Yucatan miniature swine. Abstract and poster presentation for the 34 th Annual Midwest Regional AALAS Meeting, Mid-Missouri Branch of the American Association for Laboratory Animal Science, Columbia, Missouri.
Xue B., Skala, K., Hay M. (2003) Sex differences in baroreflex function in the development of Angiotensin II-induced hypertension in conscious mice. Society of Neuroscience, 923.15.
Xue, B., Skala, K., Hay M. (2003) Gender difference in the development of Angiotensin II-induced hypertension in conscious mice. FASEB Journal, A1294:8253.
Xue, B., Skala, K., Jones, T.A., Hay, M. (2004) Diminished baroreflex control of heart rate responses in otoconia-deficient head tilt (het) mice. Am J Physiol Heart Circ Physiol, 287(2): H741-h747 Abstract
Xue, B., Pamidimukkala, J., Skala, K., Hay, M. (2004) Role of central estrogen receptors and androgen receptors in Angiotensin II-induced hypertension in conscious mice. FASEB Summer Research Conferences.
Xue, B., Pamidimukkala, J., Skala, K., Hay, M. (2004) Role of androgens and central androgen receptors in Angiotensin II-induced hypertension in the conscious male mice. Presentation for Iowa Physiological Society.
Curriculum Vitae of KARL DANIEL SKALA Page 6
BIBLIOGRAPHY continuation
Xue, B, Skala, K., Pamidimukkala, J., Hay, M. (2004) Androgens modulate Angiotensin II-induced hypertension in the conscious male mice. FASEB Journal, A649, 4396.
Xue, B., Skala, K, Pamidimukkala, J., Hay, M. (2005) Protective effect of central nitric oxide (NO) in Angiotensin II-induced hypertension in conscious female mice. IUPS/FASEB.
Skala, K., Pamidimukkala, J., Hay M. (2005) Immunohistochemical Expression of NADPH Oxidase in the Mouse Forebrain and Brainstem. FASEB Journal, A835:7651.
Olmstead, A., Skala, K, Dodam, J., Rubin, L. (2006) Modulation of Heart Rate Variability Using Androgen Receptor Blocker. The Society of Phi Zeta, University of Missouri-Columbia School of Veterinary Medicine.
ACKNOWLEDGMENTS
Kligler, D. J., Bokor, J., and Rhodes, C. K. (1980). Collisional and radiative properties of the H 2 EF Eg state. Physics Review A, 21, 607. K. Skala acknowledged for technical assistance.
Bokor, J., Zavelovich, J., and Rhodes, C. K. (1980). Isotope effect in multiphoton ultraviolet photolysis of CO. Journal of Chemical Physics, 72, 965-971. K. Skala acknowledged for technical assistance.
Hawkins, R. T., Egger, H., Bokor, J., and Rhodes C. K. (1980). A tunable, ultrahigh spectral brightness KrF *
excimer laser source. Applied Physics Letters, 36, 391-392. K. Skala acknowledged for technical assistance.
Buelke-Sam, J. C., Kimmel, C. A., Adams, J., Nelson, C. J., Vorhees, C. V., Wright, D. C., St. Omer, V., Korol, B. A., Butcher, R. E., Geyer, M. A., Holson, J. F., Kutscher, C. L., and Wayner, M. J. (1985). Collaborative Behavioral Teratology Study: Results. Neurobehavioral Toxicology and Teratology 7(6), 591-624.K. Skala acknowledged for technical assistance.
Snyder, S. W., Rigby, S. L., and Adams, H. A. (1994). The role of oxytocin in in vitro contractile activity in rat uterine tissue. Life Sciences, 55(5), 399-411. K. Skala acknowledged for technical assistance.
Snyder, S. W. (1994). Selective effects of platelet activating factor and prostaglandin F 2a on pregnant rat uterine contractility in vitro. American Journal of Obstetrics and Gynecology. K. Skala acknowledged for technical assistance.