Curriculum Vitae

2016/11/11 郭和昌

Curriculum Vitae

Name: Ho-Chang Kuo, MD, PhD, FAAAAI. (郭 和 昌)

Sex: Male

Birth Date: March 01, 1973

Birth Place: Taiwan

Citizenship: Taiwan

Open Researcher and Contributor ID (ORCID) ID:

http://orcid.org/0000-0002-3295-2984

Office Address & TEL NO.: Kawasaki Disease Center and Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, 123 Ta-Pei Road, Niaosong District, Kaohsiung, Taiwan.

Language: Chinese

Education: (MD)

-June 1999, College of Medicine, National Yang-Ming University, Taipei, Taiwan.

Post-Graduate Education: (PhD)

-2004-2011 Graduate Institute of Clinical Medical Science, Chang Gung University, Taiwan.

Academic Appointment:

-2004 Attending Staff, Department of Pediatrics Allergy, Immunology and Rheumatology, Kaohsiung Chang Gung Memorial Hospital, Taiwan.

-2008 Lectorate attending physician of Kaohsiung Chang Gung Memorial Hospital, Taiwan.

-2009 Lectorate attending physician of Chang Gung University, Taiwan.

-2010 Assistant Professor of Kaohsiung Chang Gung Memorial Hospital, Taiwan.

-2011 Assistant Professor of Chang Gung University, Taiwan.

-2013 Associate Professor of Kaohsiung Chang Gung Memorial Hospital, Taiwan.

-2015 Associate Professor of Chang Gung University, Taiwan.

-2017 Professor of Kaohsiung Chang Gung Memorial Hospital, Taiwan.

Employment Record:

1998-1999 Internship, VGH-Kaohsiung

2001-2004 Residency, Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Taiwan.

2004-2007 Fellowships, Division of Allergy, Immunology and Rheumatology, Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Taiwan.

2004- Attending Staff, Division of Allergy, Immunology and Rheumatology, Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Taiwan

2008- Lectorate attending physician of Kaohsiung Chang Gung Memorial Hospital, Taiwan.

2010- Assistant Professor physician of Kaohsiung Chang Gung Memorial Hospital, Taiwan.

2011- Assistant Professor of Chang Gung University, Taiwan.

2013- Associate Professor of Kaohsiung Chang Gung Memorial Hospital, Taiwan.

2015- Associate Professor of Chang Gung University, Taiwan.

Professional Affiliations: (Medical Organizations or Societies)

1. Taiwan Pediatric Association (NO.: 4935)

2. The Chinese Society of Pediatric Allergy, Asthma and Immunology (NO.: 751)

3. The Chinese Society of Immunology (NO.: 1684)

4. Member of Asia Society for Pediatric Research (ASPR). No. 10435 (since 2006 ~ now).

5. American Academy of Allergy Asthma and Immunology (AAAAI): International member (No.106255)

6. International Fellow of American Academy of Allergy Asthma and Immunology (FAAAAI): since 2013

7. European Academy of Allergy and Clinical Immunology (EAACI): Member (No. EAACI09486) (since 2010~)

8. OCM for Autoimmunity Series Conferences, Organizing Committee, Autoimmunity

　October 13-14, 2016 Manchester, UK.

Research Project:

Principle Investigator

1. The bio-markers and immunopathogenesis of coronary artery lesions on Kawasaki disease.

Research grant: Cardiac Children’s Foundation Taiwan. No. CCF07-01, 2007-2008. (400,000)

2. The augmented SOCS-1 expression on TLR4 dependent pathway of Kawasaki disease.

Research grant: Chang Gung Medical Research Program: No. CMRPG860421 and CMRPG860422: 2007-2009. (NT$: 800,000)

3. DC-SIGN polymorphism with coronary artery lesion in Kawasaki disease.

Research grant: NSC 97-2314-B-182A-054-MY2 (2008 - 2010), (NMRPG 876061) (NT$: 2,200,000)

4. Impact of IL2RA variants on the coronary artery lesions of Kawasaki disease.

Research grant: ：NSC 100-2314-B-182A-048 -MY3 (2011/07-2014/06)

: NSC 100-2314-B-182-061-MY3 (NT$: 2,550,000)

5. Epigenetic change impact on the atopy modulation after LGG administration.

Research grant: CMRPG8A0481. (2012/03-2013/02) (NT$: 1,099,200)

6. Prenatal dexamethasone exposure augment Th2-related immune response via epigenetic regulation. (2011-2012) Research grant: CMRPG8B0151. (NT$: 1,149,200)

7. The correlation between cytokines change and hemodynamic change after change ECMO setting.

(2011/2013) Research grant: CMRPG8B0211 (1,795,000)

8. Epigenetic study of Kawasaki disease and coronary artery lesions. NSC 102-2314-B-182-053-MY3 (2013-2016) (4,440,000)

9. Epigenetic and immune response in Kawasaki disease (OMRPG8C0041) (2013-2016) (6,000,000)

10. Neurodevelopment and cognition in children after Kawasaki disease. (CMRPG8C1081~2) (2014-2015) (1,203,315)

11. Epigenetic study of childhood cohort study with allergic diseases and neuropsychiatric survey. (CMRPG8D0521)(2014/07-2015/08)(1140000)

12. Aberrant macrophages and epigenetic in atopic dermatitis of childhood. (CMRPG8D1561 、CMRPG8D1562 )(2014/01-2015/12) (1172660+1200000)

13. 整合型計畫總主持人 (2015-2016)( CMRPG8E0021, CMRPG8E0031, CMRPF6E0041, CMRPG8E0051, CMRPG8E0061)

14. T cell receptor in Kawasaki disease (3 years) (CORPG8F0011-2) (NTS: 3190000)

15. 衛生福利部- 104年度兒科重難症醫療照護團隊獎勵方案-兒童心臟科之川崎症推廣及全面照護方案 (KMRP415)

16. 衛生福利部- 105年度兒科重難症醫療照護團隊獎勵方案-兒童心臟科之川崎症推廣及全面照護方案(KMRPB8G001、KMRPB8F003)

17. 探討川崎症造成動脈血管鈣化之病理機制 (CMRPG8E0211-2陳政男教授、張順福老師) 2016-2018.

18. 應用大腸桿菌蛋白質微陣列晶片分析川崎症之免疫機制（傑出研究人員獎勵金） (OMRPG8D0011) 2015-2017/12 (6000000)

19. Fc gamma接受器於川崎症的表現及對疾病影響 (科技部2016-2019, NTS 3750000) (MOST: 105-2314-B-182 -050 -MY3)

20. 川崎症後對注意力的影響 (2016-2019) (CMRPG8E1611)

21. 川崎症精準醫學整合型計畫總主持人（2017/03-2018/02）(CMRPG8F1911, 1921, 1931, 1941)

22. 多中心、隨機分配、平行組別、開放性、非劣性試驗設計，比較川崎症兒童於急性期「單獨使用免疫球蛋白」與「免疫球蛋白併用高劑量阿斯匹靈」在預防冠狀動脈病變的有效性試驗(CPRPG8F0791, 2017/06-2018/05)

23.

Bibliography:

Publications: (*corresponding author)

Year 2005 (SCI: 2)

1. Chih-Lu Wang, Yu-Tsun Wu, Chieh-An Liu, Ho-Chang Kuo, Kuender D. Yang. Kawasaki disease: infection, immunity and genetics. Pediatr Infect Dis J. 2005;24:998-1004. (SCI).

2. Hong-Ren Yu, Rong-Fu Chen, Kuo-Ching Hong, Chin-Nam Bong, Wen-I Lee, Ho-Chang Kuo, Kuender D. Yang. IL-12-independent Th1 polarization in human mononuclear cells infected with varicella-zoster virus. Eur J Immunol. 2005;35:3664-3672. (SCI).

Year 2006 (non-SCI: 2)

3. Ho-Chang Kuo, Yu-Tsun Wu, Kuender D. Yang, Chih-Lu Wang. New concepts and treatment strategy in Kawasaki disease. Acta Paediatr Taiwan. 2006;47(suppl):7-17.

4. Ho-Chang Kuo, Jiunn-Ming Sheen, Kuan-Sheng Wu, Hsiu-Hui Wei, Chih-Cheng Hsiao. Precocious puberty due to human chorionic gonadotropin-secreting pineal tumor. Chang Gung Med J. 2006;29:198-202.

Year 2007 (SCI total 5)

5. Ho-Chang Kuo, Kuender D. Yang, Chi-Di Liang, Chin-Nam Bong, Hong-Ren Yu, Lin Wang, Chih-Lu Wang. The relationship of eosinophilia to intavenous immunoglobulin treatment failure in Kawasaki disease. Pediatr Allergy Immunol. 2007;18:354-359. (SCI IF: 2.723).

6. Ho-Chang Kuo, Chih-Lu Wang, Chi-Di Liang, Hong-Ren Yu, Hsin-Hsu Chen, Lin Wang, Kuender D. Yang. Persistent monocytosis after intravenous immunoglobulin therapy correlated with the development of coronary artery lesions in patients with Kawasaki disease. J Microbiol Immunol Infect. 2007;40:395-400. (SCI IF:1.116)

7. Hsin-Hsu Chen, Ho-Chang Kuo, Ling Wang, Hong-Ren Yu, Jiun-Min Shen, Kao-Pin Hwang, Kuender D. Yang. Childhood macrophage activation syndrome different from infection-associated hemophagocytosis syndrome in etiology and outcome in Taiwan. J Microbiol Immunol Infect. 2007;40:265-271. (SCI IF:1.116)

8. Lin Wang, Rong-Fu Chen, Jien-Wei Liu, Hong-Ren Yu, Ho-Chang Kuo, Kuender D. Yang. Implications of dynamic changes among TNF, membrane TNF receptor and soluble TNF receptor levels in the severity of Dengue infection. Am J Trop Med Hyg. 2007;77:297-302. (SCI>2.0).

9. Kuender D. Yang, Chia-Yo Ou, Tei-Yao Hsu, Jen-Chia Chang, Hau Chuang, Chia-An Liu, Hshu-Mei Liang, Ho-Chang Kuo, Ron-Fu Chen and En-Yen Huang. Interaction of maternal atopy, CTLA-4 gene polymorphism and gender on antenatal IgE production. Clin Exp Allergy. 2007;37:680-687. (SCI IF: 4.08).

Year 2008 (SCI total 3)

10. Ho-Chang Kuo, Chih-Lu Wang, Lin Wang, Hong-Ren Yu, Kuender D. Yang. Patient characteristics and intravenous immunoglobulin product may affect eosinophils in Kawasaki disease. Pediatr Allergy Immunol. 2008;19:184-185. (SCI IF: 3.376, ranking 9/121 in Pediatrics).

11. Hong-Ren Yu, Jiunn-Ming Sheen, Kao-Pin Hwang, Ho-Chang Kuo, Eng-Yen Huang, Yi-Chuan Huang. Typhoid Fever in Southern Taiwan: A Medical Center Experience. Pediatr Neonatol. 2008;49:116-120. (SCI IF:0.932, ranking 85/121 in Pediatrics)

12. Say-Tin Yeap, Jiunn-Ming Sheen, Ho-Chang Kuo, Kao-Pin Hwang, Kuender D. Yang, Hong-Ren Yu. Macrophage Activation Syndrome as Initial Presentation of Systemic Lupus Erythematosus. Pediatr Neonatol. 2008;49:39-42. (SCI IF:0.932, ranking 85/121 in Pediatrics)

Year 2009 (total 7; SCI: 6; non-SCI: 1)

13. Ho-Chang Kuo, Chih-Lu Wang, Chi-Di Liang, Chien-Fu Huang, Hong-Ren Yu, Lin Wang, Kao-Pin Hwang, Kuender D. Yang. The association of lower Eosinophil-related T Helper 2 (Th2) Cytokines with the Coronary Artery Lesions in Kawasaki disease. Pediatr Allergy Immunol 2009;20:266-272. (SCI IF: 3.376, ranking 9/121 in Pediatrics).

14. Hong-Ren Yu, Ho-Chang Kuo, Jiunn-Ming Sheen, Lin Wang, I-Chun Lin, Chih-Lu Wang, Kuender D. Yang. A unique plasma proteomic profiling with imbalanced fibrinogen cascade in patients with Kawasaki disease. Pediatr Allergy Immunol. 2009;20:699-707. (SCI IF: 3.376, ranking 9/121 in Pediatrics)

15. Chi-Di Liang, Ho-Chang Kuo, Kuender D. Yang, Chih-Lu Wang, Sheung-Fat Ko . Acquired Coronary Artery Fistula Complicated by Kawasaki disease. American Heart Journal. 2009;157:584-588. (SCI IF:4.497, ranking 23/122 in CARDIAC & CARDIOVASCULAR SYSTEMS).

16. Ho-Chang Kuo, Chih-Chiang Wu, Tsung-Hsien Yang, Hong-Ren Yu, Chi-Di Liang, Yi-Ju Chen, Kuender D. Yang. Non-Langerhans Cell Histiocytosis in a Child with Kawasaki disease. BMJ Case Reports 2009 [doi:10.1136/bcr.11.2008.1227]

17. Yu-Lin Huang; Meng-Ying Hsieh; Pa-Fan Hsiao; Jiunn-Ming Sheen; Hong-Ren Yu; Ho-Chang Kuo; Sung-Ting Chen; Jing-Long Huang; Kuender D. Yang; Wen-I Lee. Alopecia Areata Universalis After Phenobarbital-Induced Anti-Convulsant Hypersensitivity Syndrome. Immunological Investigations. 2009; 38:383–397. (SCI IF:1.731, ranking 113/135 in Immunology)

18. Chih-Chiang Wu, Ho-Chang Kuo, Hong-Ren Yu, Lin Wang, and Kuender D. Yang. Association of acute urticaria with Mycoplasma pneumoniae infection in hospitalized children. Ann Allergy Asthma Immunol. 2009;103:134-9. (SCI IF:3.449, ranking 5/23 in Allergy).

19. Jiunn-Ming Sheen, Ho-Chang Kuo, Hong-Ren Yu, Eng-Yen Huang, Chih-Chiang Wu, and Kuender D. Yang. Prolonged Acquired Neutropenia in Children. Pediatr Blood Cancer. 2009;53:1284-8. (SCI: 2.353, ranking 27/121 in Pediatrics).

Year 2010 (total 9; SCI: 7, non-SCI: 2)

20. Kuender D. Yang, Jen-Chieh Chang, Hau Chuang, Hsio-Mei Liang, Ho-Chang Kuo, Yun-Shien Lee, Te-Yao Hsu, Chia-Yu Ou. Gene-gene and gene-environment interactions on IgE production in prenatal stage. Allergy. 2010 Jun 1;65(6):731-9. (SCI IF:5.883, ranking: 2/23 in Allergy)

21. Ho-Chang Kuo, Kudner D. Yang. Update of treatment for Juvenile Rheumatoid Arthritis. Taiwan Medical Journal 2010; 53(4): 8-12.

22. Yu-Chen Liu, Chiu-Ping Hou, Chiu-Ming Kuo, Chi-Di Liang, *Ho-Chang Kuo. Atypical Kawasaki Disease- Review of Literature and Clinical Nursing. Hu Li Za Zhi. 2010 Dec;57(6):104-110.

23. Ho-Chang Kuo, Chi-Di Liang, Chih-Lu Wang, Hong-Ren Yu, Kao-Pin Hwang, Kuender D. Yang. Serum Albumin Level Predicts Initial Intravenous Immunoglobulin Treatment Failure in Kawasaki Disease. Acta Paediatr. 2010;99:1578-1583. (SCI IF: 1.974, ranking: 38/121 in Pediatrics)

24. Hong-Ren Yu, Chi-Di Liang, Ho-Chang Kuo, Sheung-Fat Ko, Ka-Yin Tsui, Yu-Hsiu Chung, Kao-Pin Hwang, Kuender D. Yang. Air-leak and transient coronary artery dilation in post-infectious bronchiolitis obliterans. Pediatr Int. 2010 Aug;52(4):e221-3. (SCI IF: 0.875, ranking 90/121 in Pediatrics)

25. Ho-Chang Kuo, Chieh-An Liu, Chia-Yo Ou, Te-Yao Hsu, Kuender D. Yang. Correlation between atopy and tuberculin/Candida skin test reactivity in a bacillus Calmette-Gue´rin vaccinated cohort. Allergy. 2010 Dec;65(12):1625-6. (SCI IF:5.883, ranking: 2/23 in Allergy)

26. Rong-Fu Chen, Hui-Chen Huang, Chia-Yu Ou, Te-Yao Hsu, Hau Chuang, Jen-Chieh Chang, Lin Wang, Ho-Chang Kuo, Kuender D. Yang. MicroRNA-21 expression in neonatal blood associated with antenatal IgE production and development of allergic rhinitis. Clinical & Experimental Allergy 2010;40:1482-1490. (SCI IF: 4.789, ranking 4/23 in Allergy)

27. Hong-Ren Yu, Ho-Chang Kuo, Eng-Yen Huang, Chi-Di Liang, Kao-Pin Hwang, I-Chun Lin, Jiunn-Ming Sheen, Tzu-Jou Wang, Chih-Lu Wang and Kuender D. Yang. Plasma Clusterin Levels in Predicting the Occurrence of Coronary Artery Lesions in Patients With Kawasaki Disease. Pediatr Cardiol. 2010 Nov;31(8):1151-6. (SCI IF: 1.197, ranking 71/121 in Pediatrics) (Co-1st author)

28. Hong-Ren Yu, Chen-Kuang Niu, Ho-Chang Kuo, Ka-Yin Tsui, Chih-Chiang Wu, Chien-Hung Ko, Jiunn-Ming Sheen, Eng-Yen Huang, Kuender D. Yang. Comparison of the Global Initiative for Asthma Guideline-based Asthma Control Measure and the Childhood Asthma Control Test in Evaluating Asthma Control in Children. Pediatr Neonatol 2010;51(5):273−278. (SCI IF:0.932, ranking 85/121 in Pediatrics)

Year 2011 (total 23; SCI: 22, non-SCI: 1)

29. Ho-Chang Kuo, Hong-Ren Yu, Chih-Chiang Wu, Ling-Sai Chang, Kuender D. Yang. Etanercept treatment for children with refractory juvenile idiopathic arthritis. J Microbiol Immunol Infect. 2011 Jan 13;44(1):52-56. (SCI IF: 1.631, ranking 82/116, Q3 in MICROBIOLOGY)

30. Ho-Chang Kuo, Chieh-An Liu, Chia-Yu Ou, Te-Yao Hsu, Chih-Lu Wang, Hsin-Chun Huang, Hau Chuang, Hsiu-Mei Liang, and Kuender D. Yang. Partial protein hydrolyzed infant formula decreased food sensitization but not allergic diseases in a prospective birth cohort study. Int Arch Allergy Immunol. 2011;154(4):310-317. (SCI IF: 2.248, ranking: 12/23, Q3 in Allergy)

31. Ling-Sai Chang, Ho-Chang Kuo, Chieh-Chiang Wu, Hong-Ren Yu, Lin Wang, Hsueh-Wen Chang, Kuender D. Yang. Risk Factors for Mortality of Pediatric Patients without Underlying Diseases. Pediatr Neonatol. 2011 Feb;52(1):34-7. (SCI IF:0.932, ranking 85/121 in Pediatrics)

32. Mindy Ming-Huey Guo, Kuender D. Yang, Hong-Ren Yu, *Ho-Chang Kuo Hypersensitive joint reaction after etanercept treatment in a patient with juvenile rheumatoid arthritis. J Rheumatol. 2011 Mar;38(3):577-9. (SCI IF: 3.258, ranking 11/29, Q2 in Rheumatology)

33. Ho-Chang Kuo, Chi-Di Liang, Hong-Ren Yu, Chih-Lu Wang, I-Chun Lin, Chia-An Liu, Jen-Chieh Chang, Chiu-Ping Lee, Wei-Chiao Chang, Kuender D. Yang. CTLA-4, position 49 A/G polymorphism associated with coronary artery lesions in Kawasaki disease. J Clin Immunol. 2011 Apr; 31(2):240-4. (SCI IF: 3.382, rank: 55/135, Q2 in Immunology)

34. Ho-Chang Kuo, Hong-Ren Yu, Suh-Hang Hank Juo, Kuender D. Yang, Yu-Shiuan Wang, Chi-Di Liang, Wei-Chiao Chen, Wei-Pin Chang, Chien-Fu Huang, Chou-Peen Lee, Li-Yan Lin, Yu-Chen Liu, Yuh-Cherng Guo and Wei-Chiao Chang. CASP3 (rs72689236) gene single nucleotide polymorphisms and Kawasaki disease in Taiwanese children. J Hum Genet. 2011 Feb;56(2):161-5. (SCI IF: 2.365, ranking: 91/161, Q3 in GENETICS & HEREDITY)

35. Lee WI, Huang JL, Lin SJ, Yeh KW, Chen LC, Hsieh MY, Huang YC, Kuo HC, Yang KD, Yu HR, Jaing TH, Yang CH. Clinical Aspects and Genetic Analysis of Taiwanese Patients with the Phenotype of Hyper-Immunoglobulin E Recurrent Infection Syndromes (HIES). J Clin Immunol. 2011 Apr;31(2):272-80. (SCI IF: 3.382, rank: 55/135, Q2 in Immunology)

36. Shu-Ling Kao, Hong-Ren Yu, Ho-Chang Kuo, Ka-Yin Tsui, Chih-Chiang Wu, Ling-Sai Chang, Chi-Di Liang, Yu-Hsiu Chung, and Kuender D. Yang. Higher soluble Fas ligand and transforming growth factor-( levels after omalizumab treatment: A case report. J Microbiol Immunol Infect. 2012 Feb;45(1):69-71. (2016, SCI IF:2.973, ranking 77/150, Q3 in IMMUNOLOGY), 被引用2次。

37. Ho-Chang Kuo, Yu-Chen Liu, Chi-Di Liang, Kuender D. Yang. 兒科十大棘手疾病之首--川崎症. Taiwan Medical Journal 2011;54 (2):69-73.

38. Kuo HC, Chiu CC, Chang WC, Sheen JM, Ou CY, Kuo HC, Chen RF, Hsu TY, Chang JC, Hsaio CC, Wang FS, Huang CC, Huang HY, Yang KD. Use of proteomic differential displays to assess functional discrepancies and adjustments of human bone marrow- and Wharton jelly-derived mesenchymal stem cells. J Proteome Res. 2011 Mar 4;10(3):1305-15. (SCI IF: 5.056, ranking: 10/75, Q1 in BIOCHEMICAL RESEARCH METHODS)

39. Hong-Ren Yu, Hsin-Chun Huang, Ho-Chang Kuo, Jiunn-Ming Sheen, Chia-Yo Ou, Te-Yao Hsu, and Kuender D. Yang. IFN-a production by human mononuclear cells infected with varicella-zoster virus through TLR9-dependent and independent pathways. Cell Mol Immunol. 2011 Mar;8(2):181-8. (SCI IF: 3.419, ranking: 51/135, Q2 in Immunology)

40. Lin Wang, Rong-Fu Chen, Jien-Wei Liu, Ing-Kit Lee, Chiu-Ping Lee, Ho-Chang Kuo, Shau-Ku Huang, Kuender D. Yang. DC-SIGN (CD209) Promoter 2336 A/G Polymorphism Is Associated with Dengue Hemorrhagic Fever and Correlated to DC-SIGN Expression and Immune Augmentation. PLoS Negl Trop Dis 2011; 5(1): e934. (SCI IF:4.69)

41. Hong-Ren Yu, Ho-Chang Kuo, Hsin-Chun Huang, Li-Tung Huang, You-Lin Tain, Chih-Cheng Chen, Chi-Di Liang, Jiunn-Ming Sheen, I-Chun Lin, Chi-Chiang Wu, Chia-Yu Ou, and Kuender D. Yang. GAPDH is a reliable internal control in western blot analysis of leukocyte subpopulations from children. Analytical Biochemistry. 2011 Jun 1;413(1):24-9. (SCI IF 2.582, rankng: 26/75, Q2 in CHEMISTRY, ANALYTICAL) (Co-1st author)

42. Wen-I Lee, Jing-Long Huang, Syh-Jae Lin, Kuo-Wei Yeh, Li-Chen Chen, Liang-Shiou Ou, Tsung-Chieh Yao, Meng-Ying Hsieh, Yhu-Chering Huang, Hong-Ren Yu, Ho-Chang Kuo, Kunder D. Yang and Tang-Her Jaing. Clinical, immunological and genetic features in Taiwanese patients with the phenotype of hyper-immunoglobulin E recurrent infection syndromes (HIES). Immunobiology. 2011 Aug;216(8):909-17. (SCI IF:2.814, ranking: 71/135, Q3 in Immunology)

43. Ho-Chang Kuo, Kuender D. Yang, Suh-Hang Hank Juo, Chi-Di Liang, Wei-Chiao Chen, Yu-Shiuan Wang, Chih-Hung Lee, Edward His, Hong-Ren Yu, Peng-Yeong Woon, I-Chun Lin, Chien-Fu Huang, Daw-Yang Hwang, Chou-Peen Lee, Li-Yan Lin, Wei-Pin Chang, and Wei-Chiao Chang. ITPKC single nucleotide polymorphism (rs28493229) associated with the susceptibility and coronary artery aneurysm formation in Kawasaki disease patients in a Taiwanese population. PLoS One. 2011 Apr 14;6(4):e17370. (SCI IF: 3.73, ranking: 7/56, Q1 in MULTIDISCIPLINARY SCIENCES)

44. Ho-Chang Kuo, Ying-Jui Lin, Suh-Hang Hank Juo, Yu-Wen, Hsu, Wei-Chiao Chen, Kuender D. Yang, Chi-Di Liang, Shengyu Yang, Mei-Chyn Chao, Hong-Ren Yu, Shouyan Wang, Li-Yan Lin, and Wei-Chiao Chang. Lack of Association between ORAI1/CRACM1 Gene Polymorphisms and Kawasaki Disease in Taiwanese Children. J Clin Immunol. 2011 Aug;31(4):650-5. (SCI IF: 3.382, rank: 55/135, Q2 in Immunology)

45. Ho-Chang Kuo, Wei-Chiao Chang. Genetic polymorphisms of Kawasaki disease. Acta Pharmacol Sin. 2011 Oct;32(10):1193-8 (review article, SCI IF: 2.354, ranking: 50/152, Q2 in CHEMISTRY, MULTIDISCIPLINARY)

46. Hong-Ren Yu, Hsing-Chun Kuo, Hsin-Chun Huang, Ho-Chang Kuo, Tai-Yuan Chen, Li-Tung Huang, You-Lin Tain, Chih-Cheng Chen, Jiunn-Ming Sheen, I-Chun Lin, Chia-Yo Ou, Te-Yao Hsu, Yi-Jyun Jheng and Kuender D. Yang. Identification of immunodeficient molecules in neonatal mononuclear cells by proteomic differential displays. Proteomics. 2011 Sep;11(17):3491-500. (SCI IF: 4.132, ranking: 14/75, Q1 in BIOCHEMICAL RESEARCH METHODS)

47. Ming-Feng Hou, Ho-Chang Kuo, Jih-Heng Li, Yu-Shiuan Wang, Chen-Chia Chang, Ku-Chung Chen, Wei-Chiao Chen, Chien-Chih Chiu, Shengyu Yang and Wei-Chiao Chang. Orai1/CRACM1 Overexpression Suppresses Cell Proliferation via Attenuation of the Store-Operated Calcium Influx-mediated Signalling Pathway in A549 Lung Cancer Cells. Biochim Biophys Acta. 2011 Dec;1810(12):1278-84. (SCI IF: 3.848, ranking: 15/72, Q1 in BIOPHYSICS) (Co-1st author)

48. Lee WI, Huang JL, Jaing TH, Shyur SD, Yang KD, Chien YH, Chiang BL, Soong WJ, Chiou SS, Shieh CC, Lin SJ, Yeh KW, Chen LC, Ou LS, Yao TC, Lin TY, Chiu CH, Huang YC, Wu KH, Lin CY, Yu HH, Yang YH, Yu HR, Yen HJ, Hsieh MY, Kuo ML, Hwu WL, Tsai YC, Kuo HC, Lin YL, Shih YF, Chang KW. Distribution, clinical features and treatment in Taiwanese patients with symptomatic primary immunodeficiency diseases (PIDs) in a nationwide population-based study during 1985-2010. Immunobiology. 2011 Dec;216(12):1286-94. (SCI IF:2.814, ranking: 71/135, Q3 in Immunology)

49. Chou YH, Woon PY, Chen WC, Hsu YW, Chang JM, Hwang DY, Chiu YC, Kuo HC, Chang WP, Hou MF, Liu ME, Chang JG, and Chang WC. A Genetic Polymorphism (rs17251221) in the Calcium-Sensing Receptor Gene (CASR) is Associated with Stone Multiplicity in Calcium Nephrolithiasis. PLoS One. 2011;6(9):e25227. (SCI IF: 3.73, ranking: 7/56, Q1 in MULTIDISCIPLINARY SCIENCES)

50. Kuo HC, Onouchi Y, Hsu YW, Chen WC, Huang JD, Huang YH, Yang YL, Chao MC, Yu HR, Juan YS, Kuo CM, Yang KD, Huang JS and Chang WC. Polymorphisms of Transforming Growth Factor-β Signaling Pathway and Kawasaki Disease in the Taiwanese population. J Hum Genet. 2011 Dec;56(12):840-5. (SCI IF: 2.365, ranking: 91/161, Q3 in GENETICS & HEREDITY)

51. Khor CC, Davila S, Breunis WB, Lee YC, Shimizu C, Wright VJ, Yeung RS, Tan DE, Sim KS, Wang JJ, Wong TY, Pang J, Mitchell P, Cimaz R, Dahdah N, Cheung YF, Huang GY, Yang W, Park IS, Lee JK, Wu JY, Levin M, Burns JC, Burgner D, Kuijpers TW, Hibberd ML; Hong Kong–Shanghai Kawasaki Disease Genetics Consortium, Lau YL, Zhang J, Ma XJ, Liu F, Wu L; Korean Kawasaki Disease Genetics Consortium, Yoo JJ, Hong SJ, Kim KJ, Kim JJ, Park YM, Hong YM, Sohn S, Jang GY, Ha KS, Nam HK, Byeon JH, Yun SW, Han MK, Lee KY, Hwang JY, Rhim JW, Song MS, Lee HD, Kim DS, Lee JM; Taiwan Kawasaki Disease Genetics Consortium, Chang JS, Tsai FJ, Liang CD, Chen MR, Chi H, Chiu NC, Huang FY, Chang LY, Huang LM, Kuo HC, Huang KP, Lee ML, Hwang B, Huang YC, Lee PC; International Kawasaki Disease Genetics Consortium, Odam M, Christiansen FT, Witt C, Goldwater P, Curtis N, Palasanthiran P, Ziegler J, Nissen M, Nourse C, Kuipers IM, Ottenkamp JJ, Geissler J, Biezeveld M, Tacke C, Filippini L, Brogan P, Klein N, Shah V, Dillon M, Booy R, Shingadia D, Bose A, Mukasa T, Tulloh R, Michie C; US Kawasaki Disease Genetics Consortium, Newburger JW, Baker AL, Rowley AH, Shulman ST, Mason W, Takahashi M, Melish ME, Tremoulet AH; Blue Mountains Eye Study, Viswanathan A, Rochtchina E, Attia J, Scott R, Holliday E, Harrap S. Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease. Nat Genet. 2011 Nov 13;43(12):1241-6. (SCI IF: 35.209, ranking 2/161, Q1 in GENETICS & HEREDITY)

Year 2012 (SCI :18, non-SCI:3)

52. Wu CC, Chen RF, Kuo HC. Different implications of paternal and maternal atopy for perinatal IgE production and asthma development. Clin Dev Immunol. 2012;2012:132142 (review article) (2015, SCI IF:3.063, ranking 56/151, Q2 in Immunology), 被引用31次。

53. Ho-Chang Kuo, Kuender D. Yang, Wei-Chiao Chang, Luo-Ping Ger, Kai-Sheng Hsieh. Kawasaki Disease: An Update on Diagnosis and Treatment. Pediatr Neonatol. 2012 Feb; 53(1):4-11. (review article) (2016, SCI IF:1.278, ranking 78/121, Q3 in Pediatrics), 被引用96次。

54. Ya-Ling Yang, Wei-Pin Chang, Yu-Wen Hsu, Wei-Chiao Chen, Hong-Ren Yu, Chi-Di Liang, Yao-Ting Tsai, Ying-Hsien Huang, , Kuender D Yang, Ho-Chang Kuo* and Wei-Chiao Chang. Lack of association between CLEC5A gene single nucleotide polymorphisms and Kawasaki disease in Taiwanese children. Journal of Biomedicine and Biotechnology. Volume 2012, Article ID 398628, 5 pages doi:10.1155/2012/398628 (corresponding author*) (2014, SCI IF: 3.169, ranking: 41/123, Q2 in Medicine, Research & Experimental), 被引用3次。

55. Kai-Cheng Lin, Chi-Di Liang, Kuender D. Yang, Hong-Ren Yu, *Ho-Chang Kuo. Monoarticular septic arthritis in a juvenile rheumatoid arthritis patient under etanercept treatment. Rheumatol Int. 2012 May;32(5):1383-5. (2016, SCI IF: 1.824, ranking: 21/30, Q3 in Rheumatology), 被引用3次。

56. Ho-Chang Kuo, Mei-Chyn Chao, Yu-Wen Hsu, Ying-Chi Lin, Ying-Hsien Huang, Hong-Ren Yu, Ming-Feng Hou, Chi-Di Liang, Kuender D. Yang, Chih-Lu Wang and Wei-Chiao Chang. CD40 gene polymorphisms associated with susceptibility and coronary artery lesions of Kawasaki disease in the Taiwanese population. TheScientificWorldJournal 2012;2012:520865. (2010, SCI IF:1.524, ranking: 13/59, Q1 in MULTIDISCIPLINARY SCIENCES), 被引用17次。

57. Hong-Ren Yu, Wei-Pin Chang, Lin Wang, Ying-Jui Lin, Chi-Di Liang, Kuender D. Yang, Chiu-Ming Kuo, Yi-Chuan Huang, Wei-Chiao Chang, and Ho-Chang Kuo*. DC-SIGN (CD209) Promoter –336 A/G (rs4804803) Polymorphism Associated with Susceptibility of Kawasaki disease. Scientific World Journal. 2012;2012:634835 (corresponding*) (2013, SCI IF:1.219, ranking: 16/55, Q2 in MULTIDISCIPLINARY SCIENCES ), 被引用10次。

58. Ho-Chang Kuo, Ya-Ling Yang, Jiin-Haur Chuang, Mao-Meng Tiao, Hong-Ren Yu, Li-Tung Huang, Kuender D Yang, Wei-Chiao Chang, Chiu-Ping Lee, Ying-Hsien Huang. Inflammation-induced hepcidin is associated with the development of anemia and coronary artery lesions in Kawasaki Disease. J Clin Immunol. 2012 Aug;32(4):746-52. (2016, SCI IF:3.253, rank: 64/150, Q2 in Immunology), 被引用20次。

59. Wei-Chiao Chang, Cheng-Yu Liao, Wei-Chiao Chen, Yung-Ching Fan, Siou-Jin Chiu, Ho-Chang Kuo, Peng-Yeong Woon, Mei-Chyn Chao. R450H TSH receptor mutation in congenital hypothyroidism in Taiwanese children. Clinica Chimica Acta. 2012 Jun 14; 413(11-12):1004-7. (2016, SCI IF: 2.873, ranking: 8/30, Q2 in MEDICAL LABORATORY TECHNOLOGY), 被引用15次。

60. Yi-Ching Lee, Ho-Chang Kuo, Jeng-Sheng Chang, Luan-Yin Chang, Li-Min Huang, Ming-Ren Chen, Chi-Di Liang, Hsin Chi, Fu-Yuan Huang, Meng-Luen Lee, Yhu-Chering Huang, Betau Hwang, Nan-Chang Chiu, Kao-Pin Huang, Pi-Chang Lee, Li-Ching Chang, Yi-Min Liu, Ying-Ju Chen, Chien-Hsiun Chen, Taiwan Pediatric ID Alliance , Yuan-Tsong Chen, Fuu-Jen Tsai, Jer-Yuarn Wu. Two new susceptibility loci for Kawasaki disease identified through genome-wide association analysis. Nature Genetics 2012 Mar 25;44(5):522-5. (Co-1st author) (2016, SCI IF: 27.959, ranking 2/166, Q1 in GENETICS & HEREDITY), 被引用105次。

61. Li-Yan Lin, Tsung-Hsien Yang, Chi-Di Liang, Hong-Ren Yu, Kuender D. Yang, Yi-Chuan Huang, Wei-Chiao Chang, Ho-Chang Kuo*. Comparison of the laboratory data between Kawasaki disease and enterovirus after IVIG treatment. Pediatric Cardiology 2012 Dec;33(8):1269-74. (corresponding author*) (2016, SCI IF: 1.688, ranking 89/126, Q3 in CARDIAC & CARDIOVASCULAR SYSTEMS) , 被引用5次。

62. Wei-Pin Chang, Cheng-Ying Liu, Ho-chang Kuo, Chung-Min Wu, Ying-Chen Chi, Pei-Chin Chen, Der-Ming Liou. An Evaluation of Telemedicine Service Quality in Matsu. Taipei City Medical Journal 2011; 8(4): 287-299.

63. Huang YH, Yang YL, Tiao MM, Kuo HC, Huang LT, Chuang JH. Hepcidin protects against lipopolysaccharide-induced liver injury in a mouse model of obstructive jaundice. Peptides 2012 Jun;35(2):212-7. (2016, SCI IF:2.778, ranking: 73/138, Q3 in ENDOCRINOLOGY & METABOLISM), 被引用20次。

64. Chih-Jen Chen, Fu-Cheng Huang, Mao-Meng Tiao, Ying-Hsien Huang, Li-Yan Lin, Hong-Ren Yu, Kuender D Yang, Yi-Chuan Huang, Chih-Cheng Chen, Wei-Chiao Chang and Ho-Chang Kuo*. Abnormal Gallbladder Sonography is Associated with Intravenous Immunoglobulin Resistance in Kawasaki Disease. Scientific World Journal. 2012;2012:485758. (corresponding*) (2013, SCI IF:1.219, ranking: 16/55, Q2 in MULTIDISCIPLINARY SCIENCES ), 被引用17次。

65. Chia-Hao Chen, Li-Yan Lin, Kuender D. Yang, Kai-Sheng Hsieh, Ho-Chang Kuo*. Kawasaki disease with G6PD deficiency - report of one case and literature review. J Microbiol Immunol Infect. 2014 Jun;47(3):261-3. (corresponding author*) (2016, SCI IF:2.973, ranking 77/150, Q3 in IMMUNOLOGY), 被引用5次。

66. Lin IC, Kuo HC, Lin YJ, Wang FS, Wang L, Huang SC, Chien SJ, Huang CF, Wang CL, Yu HR, Chen RF, Yang KD. Augmented TLR2 Expression on Monocytes in both Human Kawasaki Disease and a Mouse Model of Coronary Arteritis. PLoS One. 2012;7(6):e38635. (2016, SCI IF:2.806, ranking: 15/64, Q1 in MULTIDISCIPLINARY SCIENCES) , 被引用25次。

67. Pei-Chen Hou, Hong-Ren Yu, Ho-Chang Kuo, Lin Wang, Li-Yan Lin, Jiunn-Ming Sheen, Te-Yao Hsu, Chia-Yu Ou, Yi-Jyun Jheng, Kuender D Yang and Wen-Hsin Cheng. Different modulating effects of adenosine on neonatal and adult polymorphonuclear leukocytes. TheScientificWorldJournal 2012;2012:387923. (2010, SCI IF:1.524, ranking: 13/59, Q1 in MULTIDISCIPLINARY SCIENCES), 被引用5次。

68. Chia-Yu Ou, *Ho-Chang Kuo, Lin Wang, Te-Yao Hsu, Hau-Chuang, Chieh-An Liu, Jen-Chieh Chang, Hong-Ren Yu, Kuender D. Yang. Prenatal and Postnatal Probiotics Reduces Maternal but not Childhood Allergic Diseases: a Randomized, Double-Blind, Placebo-Controlled Trial. Clinical and Experimental Allergy 2012 Sep;42(9):1386-96. (co-1st author, 2016, SCI IF: 5.264, ranking 29/150, Q1 in IMMUNOLOGY) (Selected as Editor’s Choice)** , 被引用39次。

69. Ho-Chang Kuo and Wei-Chiao Chang. The Genomics and Pharmacogenomics of Kawasaki Disease. J Cell Sci Ther 2012, 3:6. (editorial) , 被引用1次。

70. Yu-Chen Liu, Ying-Hsien Huang, Ying-Jui Lin, and Ho-Chang Kuo*. Diagnosis of atypical Kawasaki disease using the new American Heart Association criteria: Reports of 2 cases and a review of the literature. Journal of Medical Sciences. (corresponding author*)

Year 2013 (SCI: 9; non-SCI: 2)

71. I-Chun Lin, Jau-Ling Suen, Shau-Ku Huang, Shun-Chen Huang, Hsin-Chun Huang, Ho-Chang Kuo, Chi-Chen Wei, Feng-Shen Wang, Hong-Ren Yu, Kuender D. Yang. Dectin-1/Syk signaling is involved in Lactobacillus casei cell wall extract-induced mouse model of Kawasaki disease. Immunobiology 2013 Feb;218(2):201-12. (2016, SCI IF:2.720, ranking: 87/150, Q3 in Immunology) , 被引用15次。

72. Kuo KC, Kuo HC, Huang LT, Lin CS, Yang SN. The clinical implications of ABO blood groups in Pseudomonas aeruginosa sepsis in children. J Microbiol Immunol Infect. 2013 Apr;46(2):109-14. (SCI IF: 1.631, ranking 82/116, Q3 in MICROBIOLOGY) (2016, SCI IF:2.973, ranking 77/150, Q3 in IMMUNOLOGY), 被引用14次。

73. Ying-Jui Lin, I-Chun Lin, Hong-Ren Yu, Hsuan-Chang Kuo, Kuender D. Yang, Wei-Chiao Chang, Chi-Di Liang, Shih-Feng Liu, Ho-Chang Kuo*. Tricuspid Regurgitation in Acute Phase of Kawasaki Disease Associated With Intensive Care Unit Admission. Pediatr Cardiol. 2013 Feb;34(2):250-5. (corresponding author*,2016, SCI IF: 1.688, ranking 89/126, Q3 in CARDIAC & CARDIOVASCULAR SYSYEM), 被引用5次。

74. Yu-Wen Hsu, Hsu-Chen Chien, Chi-Cheng Liang, Kuender D. Yang, Wei-Pin Chang, Ho-Chang Kuo*, Wei-Chiao Chang. Stromal Interaction Molecule 1 Polymorphisms are Associated with Coronary Artery Dilation but not with Aneurysm Formation in Patients with Kawasaki Disease. Journal of Experimental and Clinical Medicine. (corresponding author*)

75. Ho-Chang Kuo, Wei-Chiao Chang, Kuender D Yang, Hong-Ren Yu, Chih-Lu Wang, Shu-Chen Ho, Chun-Yuh Yang. Kawasaki disease and subsequent risk of allergic diseases: a population-based matched cohort study. BMC Pediatrics 2013 Mar 23;13:38. (2016, SCI IF:2.071, ranking 43/121, Q2 in Pediatrics) , 被引用17次。

76. Chiu-Ping Lee , Ying-Hsien Huang , Yu-Wen Hsu , Kuender D. Yang , Hsu-Chen Chien , Hong-Ren Yu , Ya-Ling Yang , Chih-Lu Wang , Wei-Chiao Chang, Ho-Chang Kuo*. TARC/CCL17 Gene Polymorphisms and Expression Associated with Susceptibility and the Formation of Coronary Artery Aneurysms in Kawasaki Disease. Pediatr Res. 2013 Nov;74(5):545-51. (2016, SCI IF:2.882, ranking 17/121, Q1 in Pediatrics) (corresponding author*), 被引用10次。

77. Ho-Chang Kuo, Yu-Wen Hsu, Chung-Min Wu, Shawn Hsiang-Yin Chen, Kuo-Sheng Hung, Wei-Pin Chang, Kuender D. Yang, Kai-Sheng Hsieh, Wei-Chiao Chen, Yoshihiro Onouchi, and Wei-Chiao Chang. A Replication Study for Association of ITPKC and CASP3 Two-locus analysis in IVIG unresponsiveness and coronary artery lesion in Kawasaki disease. PLoS One. 2013 Jul 24;8(7):e69685.(2016, SCI IF:2.806, ranking: 15/64, Q1 in MULTIDISCIPLINARY SCIENCES) , 被引用14次。

78. Deniz Yeter, Richard Deth, Ho-Chang Kuo*. Mercury promotes catecholamines which potentiate mercurial autoimmunity and arterial vasodilation: implications for ITPKC susceptibility in Kawasaki syndrome. Korean Circ J. 2013 Sep;43(9):581-591. (corresponding author*) (2016, SCI IF:1.252, ranking: 104/126, Q4 in MU CARDIAC & CARDIOVASCULAR SYSYEM) , 被引用3次。

79. Wei-Pin Chang, Shyh-JongWu, Wei-Chiao Chang, and Ho-Chang Kuo*. Population-Based Study of the Association between Urbanization and Kawasaki Disease in Taiwan. TheScientificWorldJournal 2013, Article ID 169365. (2010, SCI IF:1.524, ranking: 13/59, Q1 in MULTIDISCIPLINARY SCIENCES), 被引用10次。(corresponding author*)

80. Mei-Chen Ou-Yang, Ho-Chang Kuo, I-Chun Lin, Jiunn-Ming Sheen, Fu-Chen Huang, Chih-Cheng Chen, Ying-Hsien Huang, Ying-Jui Lin, and Hong-Ren Yu. Plasma clusterin concentrations may predict resistance to intravenous immunoglobulin in patients with Kawasaki disease. TheScientific WorldJournal, 2013, Article ID 382523, (2010, SCI IF:1.524, ranking: 13/59, Q1 in MULTIDISCIPLINARY SCIENCES), 被引用5次。(co-1st author*)

81. Chia-Jung Chang, Ho-Chang Kuo, Jong-Keuk Lee, Chiea Chuen Khor, Li-Ching Chang, Yi-Min Liu, Ying-Ju Chen, Young Mi Hong, Gi Young Jang, Martin L. Hibberd, Taco Kuijpers, David Burgner, Michael Levin, Jane Burns, Sonia Davila, International Kawasaki Disease Genetics Consortium, Korean Kawasaki Disease Genetics Consortium, Taiwan Kawasaki Disease Genetics Consortium, Yuan-Tsong Chen, Chien-Hsiun Chen, Jer-Yuarn Wu & Yi-Ching Lee. Replication of GWAS identification of Kawasaki disease susceptibility genes and a functional study affirm a role for BLK in disease susceptibility. PLoS One. 2013 Aug 30;8(8):e72037. (2016, SCI IF:2.806, ranking: 15/64, Q1 in MULTIDISCIPLINARY SCIENCES)。

82. Chang JC, Kuo HC, Hsu TY, Ou CY, Liu CA, Chuang H, Liang HM, Huang HW, Yang KD. Different Genetic Associations of the IgE Production among Fetus, Infancy and Childhood. PLoS One. 2013 Aug 1;8(8):e70362. (2016, SCI IF:2.806, ranking: 15/64, Q1 in MULTIDISCIPLINARY SCIENCES), 被引用11次。

83. Peng Yeong Woon, Wei Chiao Chang, Chi-Cheng Liang, Chun Hung Hsu, Sukhontip Klahan, Ying-Hsien Huang, Wei-Pin Chang and Ho-Chang Kuo.* Increased Risk of Atopic Dermatitis in Preschool Children with Kawasaki Disease: A Population-based Study in Taiwan. Evid Based Complement Alternat Med. 2013;2013:605123 (corresponding author*) (SCI) ), 被引用13次。

84. Chang WC, Yang KD, Wu MT, Wen YF, Hsi E, Chang JC, Lin YM, Kuo HC*, Chang WP. Close correlation between season of birth and the prevalence of bronchial asthma in a Taiwanese population. PLoS One. 2013 Nov 20;8(11):e80285. (corresponding author*)(2016, SCI IF:2.806, ranking: 15/64, Q1 in MULTIDISCIPLINARY SCIENCES), 被引用3次。

85. Burns JC, Herzog L, Fabri O, Tremoulet AH, Rodó X, Uehara R, Burgner D, Bainto E, Pierce D, Tyree M, Cayan D; Kawasaki Disease Global Climate Consortium. Dahdah N, Gibbon M, Scuccimarri R, McCrindle B, Manlhiot C, Jin CJ, Jin LH, Jin ZY, Piao JH, Zhou Y, Jiao F, Huang GY, Salo E, Cimaz R, Di-Filippo S, Lega JC, Aulakh R, Singh S, Suri D, Bar-Meir M, Cimaz R, Nakamura Y, Uehara R, Lee KY, Han JW, Han MK, Hong YM, Jang GY, Kim DS, Lee HD, Lee JK, Park IS, Song MS, Yun SW, Breunis WB, Kuijpers TW, Tacke CE, Lyskina G, Shirniskaya O, Torbyak A, Bregel L, Soldatova T, Subbotin V, Anton J, Prada F, Ricart S, Bou R, Atalay S, Çiftçi E, İnce E, Karbuz A, Özdemir H, Harnden A, Levin M, Mayon-White R, Tulloh R, Michie C, Wright V, Baker AL, Newburger JW, Innocentini N, Shulman S, Anderson M, Dominguez S, Glode M, Arrieta A, Dozal C, Mason W, Beck J, Burns J, Tremoulet A, Fernandez S, Magalhaes CM, Pratesi R, Cheung YF, Reyes M, Advani N, Olugbuyi O, Pierre R, Castaño E, Estripeaut D, Sáez-Llorens X, Chen C, Choo T, Tan T, Wong K, Kuo HC, Lin MT, Wu MH, Sittiwangkul R, Melish M, Burgner D, Odam M, Salgado A, Soza G, Doran J, Heaton P, Wilson N, Eley B, Moore D. Seasonality of Kawasaki disease: a global perspective. PLoS One. 2013 Sep 18;8(9):e74529. doi: 10.1371/journal.pone.0074529. eCollection 2013. (2016, SCI IF:2.806, ranking: 15/64, Q1 in MULTIDISCIPLINARY SCIENCES), 被引用50次。

Year 2014 (SCI 12, non SCI 2)

86. Tiao MM, Wang FS, Huang LT, Chuang JH, Kuo HC, Yang YL, Huang YH. MicroRNA-29a protects against acute liver injury in a mouse model of obstructive jaundice via inhibition of the extrinsic apoptosis pathway. Apoptosis. 2014 Jan;19(1):30-41. (2016, SCI IF:3.833, ranking: 75/189, Q2 in CELL BIOLOGY), 被引用29次。

87. Kuo HC, Hsu YW, Lo MH, Huang YH, Chien SC, Chang WC. Single-Nucleotide Polymorphism rs7251246 in ITPKC Is Associated with Susceptibility and Coronary Artery Lesions in Kawasaki Disease. PLoS One. 2014 Mar 12;9(3):e91118. (2016, SCI IF:2.806, ranking: 15/64, Q1 in MULTIDISCIPLINARY SCIENCES), 被引用11次。

88. Ho-Chang Kuo, Chung-Min Wu, Wei-Pin Chang, Chun-Nan Kuo, Deniz Yeter, Chun-Yi Lin, Jei-Tsung Pai, Ying-Chen Chi, Chia-Hsien Lin, Liang-Jen Wang and Wei-Chiao Chang. Association between Kawasaki Disease and Autism: A Population-Based Study in Taiwan. Int. J. Environ. Res. Public Health 2014 11(4), 3705-3716. (2016, SCI IF:2.101, ranking: 101/229, Q2 in ENVIRONMENTAL SCIENCES), 被引用6次。

89. Yu HR, Kuo HC, Chen CC, Sheen JM, Tiao MM, Tain YL, Huang LT. L-arginine modulates neonatal lymphocyte proliferation through IL-2 independent pathway. Immunology. 2014 Oct;143(2):184-92. (2016, SCI IF:3.701, ranking: 53/150, Q2 in IMMUNOLOGY), 被引用11次。

90. Wu TH, Kuo HC, Tain YL, Lin KM, Kuo HC, Chien SJ. Common carotid artery intima-media thickness is useful for diagnosis of the acute stage of Kawasaki disease. BMC Pediatr. 2014 Apr 10;14(1):98. (2016, SCI IF:2.071, ranking 43/121, Q2 in Pediatrics) , 被引用11次。

91. Tain YL, Chen CC, Sheen JM, Yu HR, Tiao MM, Kuo HC, Huang LT. Melatonin attenuates prenatal dexamethasone-induced blood pressure increase in a rat model. J Am Soc Hypertens. 2014 Apr;8(4):216-26. (2016, SCI IF:3.263, ranking24/63, Q2 in PERIPHERAL VASCULAR DISEASE) , 被引用21次。

92. Tiao MM, Huang LT, Chen CJ, Sheen JM, Tain YL, Chen CC, Kuo HC, Huang YH, Tang KS, Chu EW, Yu HR. Melatonin in the Regulation of Liver Steatosis following Prenatal Glucocorticoid Exposure. Biomed Res Int. 2014;2014:942172. (2016, SCI IF:2.476, ranking65/128, Q3 in MEDICINE, RESEARCH & EXPERIMENTAL) , 被引用13次。

93. Huang YH, Tain YL, Lee CP, Kuo HC*. Asymmetric and Symmetric Dimethylarginine Are Associated with Coronary Artery Lesions in Kawasaki Disease. J Pediatr. 2014 Aug;165(2):295-9.. (corresponding author*) (SCI IF:4.122, ranking4/124, Q1 in Pediatrics) , 被引用1次。

94. Yu HR, Kuo HC, Chen CC, Sheen JM, Tiao MM, Chen YC, Chang KA, Tain YL, Huang LT. Prenatal dexamethasone exposure in rats results in long-term epigenetic histone modifications and tumor necrosis factor-α production decrease. Immunology. 2014 Dec;143(4):651-60. (2016, SCI IF:3.701, ranking: 53/150, Q2 in IMMUNOLOGY), 被引用16次。

95. Shih-Chieh Wei, Chih-Fang Huang, Shiau-Ru Chiou, Ho-Chang Kuo*. Use of adalimumab in a patient with juvenile idiopathic arthritis refractory to etanercept: A case report and literature review. Austin J Pediatr. 2014;1(2): 1009. (corresponding author*)

96. Wan-Ning Tseng, Mao-Hung Lo, Kai-Sheng Hsieh, Wei-Chiao Chang, Ho-Chang Kuo*. IL-31 associated with coronary artery lesion formation in Kawasaki disease. PLoS One. 2014 Aug 14;9(8):e105195. PLoS One. 2013 Aug 30;8(8):e72037. (2016, SCI IF:2.806, ranking: 15/64, Q1 in MULTIDISCIPLINARY SCIENCES), 被引用8次。

97. Ho-Chang Kuo, Ying-Hsien Huang, Shu-Chen Chien, Hong-Ren Yu, Kai-Sheng Hsieh, Yu-Wen Hsu, and Wei-Chiao Chang. Genetic variants of CD209 associated with Kawasaki disease susceptibility. PLoS One. 2014 Aug 22;9(8):e105236 (2016, SCI IF:2.806, ranking: 15/64, Q1 in MULTIDISCIPLINARY SCIENCES), 被引用3次。

98. Sandi C Lin, Wan-Lin Tseng, Mindy Ming-Huey Guo and Ho-Chang Kuo*. Etanercept as Rescue Therapy for Refractory Kawasaki Disease. Austin J Pediatr. 2014;1(2): 1010. (corresponding author*)

99. Wu CC, Ou CY, Chang JC, Hsu TY, Kuo HC, Liu CA, Wang CL, Chuang CJ, Chuang H, Liang HM, Yang KD. Gender-dependent effect of GSTM1 genotype on childhood asthma associated with prenatal tobacco smoke exposure. Biomed Res Int. 2014;2014:769452. (2016, SCI IF:2.476, ranking65/128, Q3 in MEDICINE, RESEARCH & EXPERIMENTAL), 被引用2次。

100. Kuo HC, Guo MM, Liu SF, Chen CC, Sheen JM, Yu HR, Tiao MM, Tain YL, Huang LT. Cross-Fostering increases Th1/Th2 expression in a Prenatal Dexamethasone exposure rat model. PLoS One. 2014 Dec 19;9(12):e115554. (2016, SCI IF:2.806, ranking: 15/64, Q1 in MULTIDISCIPLINARY SCIENCES), 被引用5次。

Year 2015 (SCI 10, non SCI 1)

101. Kuo HC*, Chang JC, Kuo HC, Yu HR, Wang CL, Lee CP, Huang LT, Yang KD. Identification of an Association Between Genomic Hypomethylation of FCGR2A and Susceptibility to Kawasaki Disease and Intravenous Immunoglobulin Resistance by DNA Methylation Array. Arthritis Rheumatol. 2015 Mar;67(3):828-36. (2016, SCI IF:6.918, ranking: 3/30, Q1 in RHEUMATOLOGY), 被引用12次。

102. Mindy Ming-Huey Guo, Wan-Ning Tseng, Chia-Hung Ko, Hui-Mei Pan, Kai-Sheng Hsieh, Ho-Chang Kuo*. Th17- and Treg-related cytokine and mRNA expression are associated with acute and resolving Kawasaki disease. Allergy 2015 Mar;70(3):310-8. (2016, SCI IF:7.361, ranking: 20/150, Q1 in IMMUNOLOGY), 被引用31次。

103. Ko TM, Kuo HC, Chang JS, Chen SP, Liu YM, Chen HW, Tsai FJ, Lee YC, Chen CH, Wu JY, Chen YT. CXCL10/IP-10 is a Biomarker and Mediator for Kawasaki Disease. Circ Res. 2015 Feb 27;116(5):876-83. (co-1st author) (2016, SCI IF:13.965, ranking: 5/126, Q1 in IMM CARDIAC & CARDIOVASCULAR SYSTEMS), 被引用25次。

104. Lui CC, Hsu MH, Kuo HC, Chen CC, Sheen JM, Yu HR, Tiao MM, Tain YL, Chang KA, Huang LT. Effects of Melatonin on Prenatal Dexamethasone-Induced Epigenetic Alterations in Hippocampal Morphology and Reelin and Glutamic Acid Decarboxylase 67 Levels. Dev Neurosci. 2015;37(2):105-14. (2016, SCI IF:2.046, ranking: 186/258, Q3 in NEUROSCIENCES), 被引用6次。

105. Kuo HC, Hsu YW, Wu MS, Woon PY, Wong HS, Tsai LJ, Lin RK, Klahan S, Hsieh KS, Chang WC. FCGR2A Promoter Methylation and Risks for Intravenous Immunoglobulin Treatment Responses in Kawasaki Disease. Mediators Inflamm. 2015;2015:564625. (2016, SCI IF:3.232, ranking: 94/189, Q2 in CELL BIOLOGY), 被引用2次。

106. Guo MM, Tseng WN, Ou CY, Hsu TY, Kuo HC*, Yang KD. Predictive factors of persistent infantile atopic dermatitis up to 6 years old in Taiwan: a prospective birth cohort study. Allergy. 2015 Nov;70(11):1477-84. (2016, SCI IF:7.361, ranking: 20/150, Q1 in IMMUNOLOGY), 被引用4次。 (corresponding author)

107. Liu SF, Kuo HC, Tseng CW, Huang HT, Chen YC, Tseng CC, Lin MC. Leukocyte Mitochondrial DNA Copy Number Is Associated with Chronic Obstructive Pulmonary Disease. PLoS One. 2015 Sep 22;10(9):e0138716. (2016, SCI IF:2.806, ranking: 15/64, Q1 in MULTIDISCIPLINARY SCIENCES), 被引用7次。

108. Kuo HC, Chang WC, Wang LJ, Li SC, Chang WP. Association of Attention deficit hyperactivity disorder and Kawasaki disease: a nationwide population-based cohort study. Epidemiol Psychiatr Sci. 2015 Sep 22:1-8. (2016, SCI IF:4.246, ranking: 16/139, Q1 in PSYCHIATRY)。

109. Ho-Chang Kuo*, Jen-Chieh Chang, Mindy Ming-Huey Guo, Kai-Sheng Hsieh, Deniz Yeter, Sung-Chou Li, Kuender D. Yang. Gene-gene associations with the susceptibility of Kawasaki disease and coronary artery lesions. PLoS One. 2015 Nov 30;10(11):e0143056. (1st and correspondence author) (2016, SCI IF:2.806, ranking: 15/64, Q1 in MULTIDISCIPLINARY SCIENCES), 被引用3次。

110. Kuo H-C, Lo M-H, Hsieh K-S, Guo MM-H, Huang Y-H. High-Dose Aspirin Is Associated with Anemia and Does Not Confer Benefit to Disease Outcomes in Kawasaki Disease. PLoS ONE 2015, 10(12): e0144603. (2016, SCI IF:2.806, ranking: 15/64, Q1 in MULTIDISCIPLINARY SCIENCES), 被引用14次。

111. Chih-Yin Lin, Jih-Yang Ko and Ho-Chang Kuo. Hyperbaric Oxygen Therapy in a Child with Legg-Calvé-Perthes Disease. Pediatr Neonatal Care 3:115.

Year 2016 (SCI 18)

112. Yeter D, Portman MA, Aschner M, Farina M, Chan WC, Hsieh KS, Kuo HC.* Ethnic Kawasaki Disease Risk Associated with Blood Mercury and Cadmium in U.S. Children. Int J Environ Res Public Health. 2016 Jan 5;13(1). (SCI IF: 2.063, correspondence author) (2016, SCI IF:2.101, ranking: 101/229, Q2 in ENVIRONMENTAL SCIENCES), 被引用5次。

113. Tseng HC, Ho JC, Guo MM, Lo MH, Hsieh KS, Tsai WC, Kuo HC*, Lee CH. Bull's eye dermatoscopy pattern at bacillus Calmette-Guérin inoculation site correlates with systemic involvements in patients with Kawasaki disease. J Dermatol. 2016 Sep;43(9):1044-50. (SCI IF: 1.577, corresponding author) (2016, SCI IF:2.094, ranking: 26/63, Q2 in DERMATOLOGY), 被引用4次。

114. Kuo HC, Hsu YW, Wu MS, Chien SC, Liu SF, Chang WC. Intravenous immunoglobulin, pharmacogenomics, and Kawasaki disease. J Microbiol Immunol Infect. 2016 Feb;49(1):1-7. (invited review article) (2016, SCI IF:2.973, ranking:77/150, Q2 in IMMUNOLOGY), 被引用11次。

115. Yu HR, Li SC, Tseng WN, Tain YL, Chen CC, Sheen JM, Tiao MM, Kuo HC, Huang CC, Hsieh KS, Huang LT. Early and late effects of prenatal corticosteroid treatment on the microRNA profiles of lung tissue in rats. Exp Ther Med. 2016 Mar;11(3):753-762. (2016, SCI IF:1.261, ranking:100/128, Q4 in MEDICINE, RESEARCH & EXPERIMENTAL)。

116. Interferon-gamma Genetic Polymorphism and Expression in Kawasaki Disease. Huang YH, Hsu YW, Lu HF, Wong HS, Yu HR, Kuo HC, Huang FC, Chang WC, Kuo HC*. Medicine (Baltimore). 2016 Apr;95(17):e3501. ( corresponding author). (2016, SCI IF:1.803, ranking:58/154, Q2 in MEDICINE,GENERAL & INTERAL) , 被引用2次。

117. Huang YH, Kuo HC, Huang FC, Yu HR, Hsieh KS, Yang YL, Sheen JM, Li SC, Kuo HC*. Hepcidin-Induced Iron Deficiency Is Related to Transient Anemia and Hypoferremia in Kawasaki Disease Patients. Int J Mol Sci. 2016 May 12;17(5). (corresponding author) (2016, SCI IF:3.226, ranking:116/286, Q2 in BIOCHEMISTRY & MOLECULAR BIOLOGY) , 被引用3次。

118. Kuo HC, Li SC, Guo MM, Huang YH, Yu HR, Huang FC, Jiao F, Kuo HC, Andrade J, Chan WC. Genome-Wide Association Study Identifies Novel Susceptibility Genes Associated with Coronary Artery Aneurysm Formation in Kawasaki Disease. PLoS One. 2016 May 12;11(5):e0154943. (2016, SCI IF:2.806, ranking: 15/64, Q1 in MULTIDISCIPLINARY SCIENCES), 被引用3次

119. Ho-Chang Kuo, Kai-Sheng Hsieh, Mindy Ming-Huey Guo, Ken-Pen Weng, Luo-Ping Ger, Wen-Ching Chan, Sung-Chou Li. Next generation sequencing identifies miRNA-based biomarker panel for Kawasaki disease. Journal of Allergy and Clinical Immunology. 2016 Oct;138(4):1227-1230. (2016, SCI IF:13.081, ranking: 6/150, Q1 in IMMUNOLOGY)。

120. Li SC, Chan WC, Huang YH, Guo MM, Yu HR, Huang FC, Kuo HC, Kuo HC*. Major methylation alterations on the CpG markers of inflammatory immune associated genes after IVIG treatment in Kawasaki disease. BMC Med Genomics. 2016 Aug 12;9 Suppl 1:37. (SCI IF: 3.13) (corresponding author). (2016, SCI IF:2.848, ranking: 73/166, Q2 in GENETICS & HEREDITY), 被引用1次

121. Kuo HC, Yang YL, Ho SC, Guo MM, Jiang JH, Huang YH. General anesthesia exposure in early life reduces the risk of allergic diseases: A nationwide population-based cohort study. Medicine (Baltimore). 2016 Jul;95(28):e4269. (2016, SCI IF:1.803, ranking:58/154, Q2 in MEDICINE,GENERAL & INTERAL)。

122. Chen YC, Huang YH, Sheen JM, Tain YL, Yu HR, Chen CC, Tiao MM, Kuo HC, Huang LT. Prenatal Dexamethasone Exposure Programs the Development of the Pancreas and the Secretion of Insulin in Rats. Pediatr Neonatol. 2016 Jun 18. pii: S1875-9572(16)30067-5. (2016, SCI IF:1.287, ranking: 78/121, Q3 in PEDIATRICS), 被引用1次

123. Chang WP, Kuo CN, Kuo LN, Wang YT, Perng WT, Kuo HC, Wei JC. Increase risk of allergic diseases in patients with ankylosing spondylitis: A 10-year follow-up population-based study in Taiwan. Medicine (Baltimore). 2016 Nov;95(45):e5172. (2016, SCI IF:1.803, ranking:58/154, Q2 in MEDICINE,GENERAL & INTERAL)。

124. Yu HR, Tain YL, Sheen JM, Tiao MM, Chen CC, Kuo HC, Hung PL, Hsieh KS, Huang LT. Prenatal Dexamethasone and Postnatal High-Fat Diet Decrease Interferon Gamma Production through an Age-Dependent Histone Modification in Male Sprague-Dawley Rats. Int J Mol Sci. 2016 Sep 22;17(10). (2016, SCI IF:3.226, ranking:116/286, Q2 in BIOCHEMISTRY & MOLECULAR BIOLOGY) , 被引用2次。

125. Kuo HC, Wang CL, Yang KD, Lo MH, Hsieh KS, Li SC, Huang YH. Plasma Prostaglandin E2 Levels Correlated with the Prevention of Intravenous Immunoglobulin Resistance and Coronary Artery Lesions Formation via CD40L in Kawasaki Disease. PLoS One. 2016 Aug 15;11(8):e0161265. (2016, SCI IF:2.806, ranking: 15/64, Q1 in MULTIDISCIPLINARY SCIENCES), 被引用2次。

126. Liu SF, Kuo HC,* Liu GH, Ho SC, Chang HC, Huang HT, Chen YM, Huang KT, Chen KY, Fang WF, Lin MC. Inhaled corticosteroids can reduce osteoporosis in female patients with COPD. Int J Chron Obstruct Pulmon Dis. 2016 Jul 14;11:1607-14. (corresponding author) (2016, SCI IF:3.157, ranking: 20/59, Q2 in RESPIRATORY SYSTEM), 被引用2次。

127. Hong-Ren Yu, Ying-Hsien Huang, Hsing-Chun Kuo, Fu-Chen Huang, Hsin-Chun Huang, Sung-Chou Li, Kai-Sheng Hsieh, Ho-Chang Kuo*. Distinct expressions of immunoglobulin signal related molecules between human Kawasaki disease and BALB/c mice treated with Lactobacillus asei cell wall extract. Int J Clin Exp Med 2016;9(10):19502-19511. (corresponding author) (2016, SCI IF:1.069, ranking: 104/128, Q4 in MEDICINE, RESEARCH & EXPERIMENTAL)。

128. Tseng WN, Chen CC, Yu HR, Huang LT, Kuo HC.* Antenatal Dexamethasone Exposure in Preterm Infants Is Associated with Allergic Diseases and the Mental Development Index in Children. Int J Environ Res Public Health. 2016 Dec 3;13(12). (corresponding author) (2016, SCI IF:2.101, ranking: 101/229, Q2 in ENVIRONMENTAL SCIENCES), 被引用1次。

129. Yu HR, Hsu TY, Huang HC, Kuo HC, Li SC, Yang KD, Hsieh KS. Comparison of the Functional microRNA Expression in Immune Cell Subsets of Neonates and Adults. Front Immunol. 2016 Dec 19;7:615. (2016, SCI IF:6.429, ranking: 21/150, Q1 in IMMUNOLOGY), 被引用2次。

Year 2017

130. Chang LS, Lo MH, Li SC, Yang MY, Hsieh KS, Kuo HC*. The effect of FcγRIIA and FcγRIIB on coronary artery lesion formation and intravenous immunoglobulin treatment responses in children with Kawasaki disease. Oncotarget. 2017 Jan 10;8(2):2044-2052.. (corresponding author) (2016, SCI IF:5.168, ranking: 48/189, Q2 in CELL BIOLOGY), 被引用1次。

131. Huang YH, Li SC, Huang LH, Chen PC, Lin YY, Lin CC, Kuo HC*. Identifying genetic hypomethylation and upregulation of toll-like receptors in Kawasaki disease. Oncotarget. 2017 Feb 14;8(7):11249-11258. (SCI IF:5.008, corresponding author) (2016, SCI IF:5.168, ranking: 48/189, Q2 in CELL BIOLOGY), 被引用1次。

132. Lee MT, Wu CC, Ou CY, Chang JC, Liu CA, Wang CL, Chuang H, Kuo HC, Hsu TY, Chen CP, Yang KD. A prospective birth cohort study of different risk factors for development of allergic diseases in offspring of non-atopic parents. Oncotarget. 2017 Feb 14;8(7):10858-10870. (SCI: IF: 5.008) (2016, SCI IF:5.168, ranking: 48/189, Q2 in CELL BIOLOGY)。

133. Huang FC, Kuo HC, Huang YH, Yu HR, Li SC, Kuo HC. Anti-inflammatory effect of resveratrol in human coronary arterial endothelial cells via induction of autophagy: implication for the treatment of Kawasaki disease. BMC Pharmacol Toxicol. 2017 Jan 9;18(1):3. (2016, SCI IF:2.288, ranking: 142/256, Q3 in PHARMACOOGY & PHARMACY) , 被引用1次。

134. Lee ZM, Huang YH, Ho SC, Kuo HC*. Correlation of symptomatic enterovirus infection and later risk of allergic diseases via a population-based cohort study. Medicine (Baltimore). 2017 Jan;96(4):e5827. corresponding author) (2016, SCI IF:1.803, ranking:58/154, Q2 in MEDICINE,GENERAL & INTERAL), 被引用1次。

135. Huang YH, Kuo HC*. Anemia in Kawasaki Disease: Hepcidin as a Potential Biomarker. Int J Mol Sci. 2017 Apr 12;18(4). (SCI IF: 3.215, invited review, corresponding author) (2016, SCI IF:3.226, ranking:116/286, Q2 in BIOCHEMISTRY & MOLECULAR BIOLOGY) 。

136. Chen YC, Huang YH, Sheen JM, Tain YL, Yu HR, Chen CC, Tiao MM, Kuo HC, Huang LT. Prenatal Dexamethasone Exposure Programs the Development of the Pancreas and the Secretion of Insulin in Rats. Pediatr Neonatol. 2017 Apr;58(2):135-144. (2016, SCI IF:1.287, ranking: 78/121, Q3 in PEDIATRICS), 被引用1次。

137. Liu SF, Kuo HC*, Lin MC, Ho SC, Tu ML, Chen YM, Chen YC, Fang WF, Wang CC, Liu GH. Inhaled corticosteroids have a protective effect against lung cancer in female patients with chronic obstructive pulmonary disease: a nationwide population-based cohort study. Oncotarget. 2017 May 2;8(18):29711-29721. (corresponding author) (2016, SCI IF:5.168, ranking: 48/189, Q2 in CELL BIOLOGY)。

138. Chou MY, Huang LT, Tain YL, Kuo HC, Tiao MM, Sheen JM, Chen CC, Hung PL, Hsieh KS, Yu HR. Age-Dependent Effects of Prenatal Dexamethasone Exposure on Immune Responses in Male Rats. Tohoku J Exp Med. 2017;241(3):225-237. (2016, SCI IF:1.278, ranking: 99/128, Q4 in MEDICINE, RESEARCH & EXPERIMENTAL)。

139. Huang YH, Yang KD, Hsu YW, Lu HF, Wong HS, Yu HR, Kuo HC, Huang FC, Lo MH, Hsieh KS, Chen SF, Chang WC, Kuo HC*. Correlation of HAMP gene polymorphisms and expression with the susceptibility and length of hospital stays in Taiwanese children with Kawasaki disease. Oncotarget. 2017 May 8;8(31):51859-51868. (corresponding author) (2016, SCI IF:5.168, ranking: 48/189, Q2 in CELL BIOLOGY)。

140. Yu HR, Tsai CC, Chang LS, Huang HC, Cheng HH, Wang JY, Sheen JM, Kuo HC, Hsieh KS, Huang YH, Yang KD, Hsu TY. l-Arginine-Dependent Epigenetic Regulation of Interleukin-10, but Not Transforming Growth Factor-β, Production by Neonatal Regulatory T Lymphocytes. Front Immunol. 2017 Apr 25;8:487. (2016, SCI IF:6.429, ranking: 21/150, Q1 in IMMUNOLOGY), 被引用1次。

141. Kuo HC.* Preventing coronary artery lesions in Kawasaki disease. Biomed J. 2017 Jun;40(3):141-146. (invited review) (2016, SCI IF: 2.799, ranking: 111/190, Q3 in CELL BIOLOGY ), 被引用1次。

142. Chang LS, Hsu YW, Lu CC, Lo MH, Hsieh KS, Li SC, Chang WC, Kuo HC*. CYP2E1 Gene Polymorphisms Related to the Formation of Coronary Artery Lesions in Kawasaki Disease. Pediatr Infect Dis J. 2017 Nov;36(11):1039-1043. (2016, SCI IF: 2.486, ranking: 99/151, Q3 in IMMUNOLOGY)

143. Liang-Jen Wang, Ho-Chang Kuo*. Cognitive Development After Kawasaki Disease- Clinical Study and Validation Using a Nationwide Population-Based Cohort. Circ J. 2017 Sep 9. doi: 10.1253/circj.CJ-17-0557. (2016, SCI IF: 3.544, ranking: 44/126, Q2 in CARDIAC & CARDIOVASCULAR SYSTEMS), 被引用1次。

144. Kuo HC, Wong HS, Chang WP, Chen BK, Wu MS, Yang KD, Hsieh KS, Hsu YW, Liu SF, Liu X, Chang WC. Prediction for Intravenous Immunoglobulin Resistance by Using Weighted Genetic Risk Score Identified From Genome-Wide Association Study in Kawasaki Disease. Circ Cardiovasc Genet. 2017 Oct;10(5). pii: e001625. (SCI IF: 4.7) (2016, SCI IF: 4.743, ranking: 29/126, Q1 in CARDIAC & CARDIOVASCULAR SYSTEMS), 被引用2次。

145. Kuo HC, Li SC, Huang LH, Huang YH. Epigenetic hypomethylation and upregulation of matrix metalloproteinase 9 in Kawasaki disease. Oncotarget. 2017 Jul 28;8(37):60875-60891. (2016, SCI IF: 5.168, ranking: 48/190, Q2 in CELL BIOLOGY)

146. Huang LH, Lin PH, Tsai KW, Wang LJ, Huang YH, Kuo HC, Li SC. The effects of storage temperature and duration of blood samples on DNA and RNA qualities. PLoS One. 2017 Sep 19;12(9):e0184692. (Correspondence author) (2016, SCI IF: 2.806, ranking: 15/64, Q1 in MULTIDISCIPLINARY), 被引用3次。

147. Chang LS, Lee HC, Tsai YC, Shen LS, Li CL, Liu SF, Kuo HC*. Decreased incidence of glaucoma in children with asthma using inhaled corticosteroid: a cohort study. Oncotarget. 2017 Nov 1;8(62):105463-105471. (2016, SCI IF: 5.168, ranking: 48/190, Q2 in CELL BIOLOGY)

148. Kuo HC, Huang YH, Chung FH, Chen PC, Sung TC, Chen YW, Hsieh KS, Chen CS, Syu GD. Antibody Profiling of Kawasaki Disease Using Escherichia coli Proteome Microarrays. Mol Cell Proteomics. 2018 Mar;17(3):472-481. (SCI IF: 6.5) (2016, SCI IF: 6.54, ranking: 5/78, Q1 in BIOCHEMICAL RESEARCH METHODS)

149. Huang YH, Kuo HC, Li SC, Cai XY, Liu SF, Kuo HC*. HAMP promoter hypomethylation and increased hepcidin levels as biomarkers for Kawasaki disease. J Mol Cell Cardiol. 2018 Mar 2;117:82-87. (SCI IF: 5.6) (corresponding author)

150. Yang KD, Wu CC, Lee MT, Ou CY, Chang JC, Wang CL, Chuang H, Kuo HC*, Chen CP, Hsu TY. Prevalence of infant sneezing without colds and prediction of childhood allergy diseases in a prospective cohort study. Oncotarget. 2017 Nov 7;9(7):7700-7709. (2016, SCI IF: 5.168, ranking: 48/190, Q2 in CELL BIOLOGY) (corresponding author)

151. Huang YH, Lo MH, Cai XY, Kuo HC*. Epigenetic hypomethylation and upregulation of NLRC4 and NLRP12 in Kawasaki disease. Oncotarget. 2018 Apr 10;9(27):18939-18948. (2016, SCI IF: 5.168, ranking: 48/190, Q2 in CELL BIOLOGY) (corresponding author)

152. Kuo HC, Lo CC, Lin PX, Kao CC, Huang YH, Lin BS. Wireless optical monitoring system identifies limb induration characteristics in patients with Kawasaki disease. J Allergy Clin Immunol. 2018 May 4. pii: S0091-6749(18)30631-6. (SCI IF: 13.258)

153. Lee MJ, Chou MC, Chou WJ, Huang CW, Kuo HC, Lee SY, Wang LJ. Heavy Metals' Effect on Susceptibility to Attention-Deficit/Hyperactivity Disorder: Implication of Lead, Cadmium, and Antimony. Int J Environ Res Public Health. 2018 Jun 10;15(6).

154. Wang LJ, Li SC, Lee MJ, Chou MC, Chou WJ, Lee SY, Hsu CW, Huang LH, Kuo HC.* Blood-Bourne MicroRNA Biomarker Evaluation in Attention-Deficit/Hyperactivity Disorder of Han Chinese Individuals: An Exploratory Study. Front Psychiatry. 2018 May 29;9:227. (corresponding author)

155. Kuo HC*, Guo MM, Lo MH, Hsieh KS, Huang YH. Effectiveness of intravenous immunoglobulin alone and intravenous immunoglobulin combined with high-dose aspirin in the acute stage of Kawasaki disease: study protocol for a randomized controlled trial. BMC Pediatr. 2018 Jun 22;18(1):200. doi: 10.1186/s12887-018-1180-1.

156. Su YJ, Lin IC, Wang L, Lu CH, Huang YL, Kuo HC.* Next generation sequencing identifies miRNA-based biomarker panel for lupus nephritis. Oncotarget. 2018 Jun 15;9(46):27911-27919. (corresponding author)

Invited Speaker:

1. 2007 Mar. Symposium of New Concept in Juvenile Rheumatoid Arthritis. Kaohsiung, Taiwan.

2. 2007 Sep. Symposium of Rheumatoid Arthritis. Ken-ting, Taiwan.

3. 2009 May. Forum of Juvenile Rheumatoid Arthritis. 2009. Tainan, Taiwan.

4. 2009 July. Comprehensive Care for Allergic Diseases Children. Kaohsiung, Taiwan.

5. 2009 Aug. Seasonal conference of The Chinese Society of Pediatric Allergy, Asthma and Immunology. Tainan, Taiwan. (GINA guideline for 5 year and younger)

6. 2010 Mar. Seasonal conference of The Chinese Society of Pediatric Allergy, Asthma and Immunology. Tainan, Taiwan. (Childhood asthma management: from theory to clinical application)

7. 2010 June Zero tolerance approach to allergic airways (Chinese Society of Immunology) (Challenging in asthma treatment guidelines-different phenotypes, different approach).

8. 201105 Safety and effect of pimecrolimus

9. 201107 Safety and effect of pimecrolimus

10. 201210 APAPARI, Introduction of Juvenile idiopathic Arthritis, Taipei, Taiwan.

11. 20121103 Epigenetic and environment regulation of human disease.

12. 201311 Asia Pacific Congress of Allergy, Asthma and Clinical Immunology 2013 (APCAACI 2013)-Kawasaki disease.

13. 201312 台灣兒童心臟醫學會邀請專題演講-川崎症與過敏關連

14. 201411 The 51st Annual congress of Japanese Society of Pediatric Allergy and Clinical Immunology

15. 201411 Mie University Graduate School of Medicine (日本三重大學)

16. 201411湖南省醫學會

17. 201505 陝西省人民醫院兒童病院

18. 2016/10 榆林市首屆國際兒科醫學會

19. 2017/07 深圳市川崎症論壇

Honor &/or Awards:

1. Pediatric Research, Travel award of 1st Asia Society of Pediatric Research (ASPR), 2005, Tokyo Japan.

2. Physician scientist award, Institute of Biomedical Science, Academia Sinica, 2005.

3. Physician scientist award, Institute of Biomedical Science, Academia Sinica, 2006.

4. Physician scientist award, Institute of Biomedical Science, Academia Sinica, 2007.

5. The 2007 Annual Best Article Award of resident in all Chang Gung Memorial Hospitals.

6. The best research article of 2008 (Nestle), The Chinese Society of Pediatric Allergy, Asthma and Immunology.

7. 2009 Research award of Professor Wen-Chang Liu, The Chinese Society of Immunology.

8. Marquis "Who's Who in the World" (2011)

9. 2000 Outstanding Intellectuals of the 21st Century Published by International Biographical Center, Cambridge, England.

10. 2010 Man of the Year, The American Biographical Institute, ABI.

11. 2011 Pediatric Academic Societies and Asian Society for Pediatric Research (PAS/ASPR) Joint meeting, Denver, Colorado, USA. (ASPR bEST RESEARCH AWARD)

12. Be nominated for 6th International best blog in Chinese. (primary election and second ballot)

13. Physician scientist award of Chang Gung Memorial Hospital, Kaohsiung, Taiwan. (2011-2016).

14. The best research article of 2011 (Otsuka respiratory), The Chinese Society of Pediatric Allergy, Asthma and Immunology

15. The 8th Congress of Asian Society for Pediatric Research (ASPR), Seoul, Korea. 2012.-Young Investigators Award (YIA). (CD40 gene polymorphism in Kawasaki disease)

16. The 8th Congress of Asian Society for Pediatric Research (ASPR), Seoul, Korea. 2012.-Young Investigators Award (YIA). (ITPKC and CASP3 gene polymorphism in Kawasaki disease)

17. The 8th Congress of Asian Society for Pediatric Research (ASPR), Seoul, Korea. 2012.-Young Investigators Award (YIA). (Hepcidin in Kawasaki disease).

18. 科技部101年度補助大專校院獎勵特殊優秀人才獎勵

19. 2013 The National Science Council, Taiwan. (Ta-You Wu Memorial Award. 國科會吳大猷紀念獎)

20. The best research article of 2012 (MSD), The Chinese Society of Pediatric Allergy, Asthma and Immunology.

21. 2012台灣兒科醫學會-第七屆亞洲兒科研究學會與美國兒科學會聯合會優秀摘要獎

22. 2012 Research award of Professor Wen-Chang Liu, The Chinese Society of Immunology.

23. 2013 American Academy of Allergy Asthma and Immunology (AAAAI) International Young Investigator Award.

24. 2013 China Youth Corps Youth Metal. (救國團青年獎章)

25. 2013 Distinguished Alumni Award, Chang Gung University. (Chang Gung University was ranked near the top 400 place in the Shanghai Jiao Tong Academic Ranking of World Universities長庚大學傑出校友)

26. 科技部102年度補助大專校院獎勵特殊優秀人才獎勵

27. The best research article of 2013 (MSD), The Chinese Society of Pediatric Allergy, Asthma and Immunology.

28. 2013年中華民國免疫學會”沈水德翁文教基金會學術論文獎”

29. 2013 SNQ國家生技獎-國家品質標章-川崎症團隊

30. 2011, 2012, 2013連續三年榮獲高雄長庚醫院”服務優良人員”

31. 高雄長庚醫院100年度”優良教學成效醫師”

32. 2014 The 10th Congress of Asian Society for Pediatric Research (ASPR)/Pediatric Academic Societies (PAS), Vancouver, Canada. Best Research Award (ASPR)

33. 高雄長庚醫院103年甄選優良教師

34. European Academy of Allergy and Clinical Immunology (EAACI) 2014 Annual Congress, Abstract Prize Award winner, Copenhagen, Denmark. (Mindy Kuo, Th17 and Kawasaki disease)

35. 103年長庚大學優良教師(研究類)

36. 科技部103年度補助大專校院獎勵特殊優秀人才獎勵

37. 103年長庚體系王永在董事長頒發金牌”研究傑出貢獻卓越” Chang Gung Memorial Hospital System chairman awarded the gold medal in the "outstanding contribution to research excellence."

38. 2015年國立陽明大學校友總會傑出校友

39. 104年度高雄長庚醫院服務優良人員: 最佳服務優良人員

40. The best research article of 2015 (Otsuka respiratory), The Chinese Society of Pediatric Allergy, Asthma and Immunology(台灣兒童過敏氣喘免疫及風濕病醫學會:大塚呼吸優秀學術論文獎)

41. 科技部104年度補助大專校院獎勵特殊優秀人才獎勵（長庚大學）

42. 財團法人風濕病基金會台灣抗風濕病聯盟(104年度宋欽章先生紀念獎助金)

43. 中華民國呼吸治療師公會全國聯合會第十二屆呼吸治療師節國際學術研討會論文”第一名”

44. 長庚醫療財團法人104年度住院醫師優良論文獎全長庚體系第三名，指導作者

45. 2015台灣兒科醫學會-第十一屆亞洲兒科研究學會與美國兒科學會聯合會優秀摘要獎

46. The best research article of 2016 (MSD), The Chinese Society of Pediatric Allergy, Asthma and Immunology. (2016兒童過敏氣喘免疫及風濕病醫學會默沙東兒童過敏氣喘優秀學術論文獎)

47. 第13屆國家新創獎

48. 2016 SNQ國家生技獎-國家品質標章-川崎症團隊

49. 衛生福利部- 104年及105年度兒科重難症醫療照護團隊獎勵方案-兒童心臟科之川崎症推廣及全面照護方案

50. 科技部105年度補助大專校院獎勵特殊優秀人才獎勵（長庚大學）

51. 2016 Asian Society for Pediatrics Research, Bangkok, Thailand, Best Research Award. (Dr. Li)

52. Travel award, The 81st Annual Scientific Meeting of the Japanese Circulation Society (JCS) 2017. Kanazawa, Japan.

53. Travel award, The 61st Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology (JCR), Fukuoka, Japan.

54. The best research article of 2017 (Nestle), The Chinese Society of Pediatric Allergy, Asthma and Immunology(台灣兒童過敏氣喘免疫及風濕病醫學會:雀巢優秀學術論文獎)

55. 106年度高雄長庚醫學研究獎"青年研究獎"

56. The Asian Pacific Society of Respirology (APSR) Congress 2017, Sydney, Australia─Travel Award.

57. 第18屆醫療品質獎主題類菁英組金獎+創意獎

58. 2017台北國際發明暨技術交易展金獎

59. 106年度高雄長庚研究成果臨床應用獎勵第一名

60. 2017年高雄長庚醫院精實醫療專案第一名：川崎症精實醫療

61. Outstanding reviewer of The Journal of Pediatrics (ranking 4.8% in Pediatrics, Top 10% of the world)

62. 國立陽明大學第15屆傑出校友

63. Travel award, The 82st Annual Scientific Meeting of the Japanese Circulation Society (JCS) 2018. Tokyo, Japan.

Book publication: (著作)

1. 兒童發燒五天竟導致心臟病: 不可不知的川崎症 (Oct 2011 1st version, 郭和昌 醫師主編, 麗文文化事業股份有限公司出版, ISBN 13/9789577484451, SBN 10/957748445X, EAN/9789577484451)

2. Ho-Chang Kuo, Wei-Chiao Chang; " Chapter10: Cardiovascular lesions of Kawasaki

disease: From genetic study to clinical management", Current Basic and Pathological Approaches to the Function of Muscle Cells and Tissues - From Molecules to Humans. ISBN 978-953-51-0679-1, Hard cover, 390 pages, Publisher: InTech, Published: July 18, 2012.

3. Chronic Inflammation: Causes, Treatment Options and Role in Disease. Editors: Wei-Chiao Chang and Wen-Chang Chang. Chapter 5. Chronic Inflammation of Kawasaki Disease. (Ying-Hsien Huang and Ho-Chang Kuo) pp. 77-96. ISBN: 978-1-62808-094-0.

4. Chronic Inflammation: Causes, Treatment Options and Role in Disease. Editors: Wei-Chiao Chang and Wen-Chang Chang. Chapter 10. Chronic Inflammation of Biliary Atresia (Ho-Chang Kuo, Jiin-Haur Chuang and Ying-Hsien Huang) pp. 157-170. ISBN: 978-1-62808-094-0.

5. Compendium of Inflammatory Diseases, Editors: Michael Parnham, ISBN: 978-3-0348-0620-6. (Online) Title: Kawasaki Disease. DOI: 10.1007/978-3-0348-0620-6_96-1, Publisher: Springer Basel

6. 郭和昌醫師告訴你: 孩子高燒要當心, 別讓川崎症傷了寶貝的心臟，(作者: 郭和昌 出版社/貓頭鷹出版社/出版日期2013/11/05; ISBN 13/9789862621790)

7. 國際過敏免疫專家告訴你：小兒過敏指數這樣算、那樣治療與預防 (作者: 郭和昌

出版社: 貓頭鷹; 出版日：2014/4/17; ISBN：9789862622032)

8. 川崎症口袋寶貝書，郭和昌/主編；麗文文化事業股份有限公司 出版日期:2017/02/25 , ISBN

13/9789577489173。ISBN 10/9577489176；EAN/9789577489173

9.由中華川崎症關懷協會所製作之川崎寶寶Line貼圖40張，Copyright ©Kawasaki Disease Center,

2017/03 上架 (Kawasaki Disease Line stickers)

專利：

1. 中華民國專利(I580788)：用於檢測川崎症的方法及套組 （榮獲第13屆國家新創獎）

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