1

2

1

2

Immune cells

Immune competent cellICC

T NK

immune response

1antigen-recognizing phase

2lymphocyte-activating phase 3antigen-eliminating phase

1

2

12Van der Waals34

1

2

3

ACB

K=Ag+AbAg Ab

lattice theory

1

2pH6-8

337-42C

SpecificitySensitivitySimplicitySafetySaving

/

TB

TB

/

1

2

1

2

3

4

BSAHASOVAKLH

PVP

1

2

-COO + R-N+=CN-R`

H-N+-R

-COO-C-NH-R` + -NH2 O

-C-NH- + R-NH-CO-NH

R`

- NH2 + -NH2 + COH-CH2 3 - COH

-N=CH-CH2 3 CH=N-

-COOH + Cl-COO-CH2 CHCH32

O O

-C-O-C-O-CH2CHCH32 + - NH2

-CO- NH - + HO-CH2CHCH32

O O

-CH2 OH + C-O-C

CH3 CH3

O

-CH2 O-C-(CH2 ) 2-COOH

O-

-C=O +H2 N-O- CH2 - COOH

-C=N-O- CH2 - COOH

- - OH + Cl- CH2 - COONa

- - CH2 - COOH

HOOC- -NH2 + NaNO2 HOOC- -N=N

- - OH + HOOC- -N=N

- -N=N- -COOH

OH

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