60 1.

2.

-

Ubiquitin 76E1E2 E3

12

(1):

(2)4-10

TRENDS in Plant Science Vol.8 No.3 March 2003Molecular Cell, Vol. 8, 499504, September, 2001,

C-terminal side of Lys, Arg

C-term of Phe, Trp, Tyr

C-term of val, Ala, Ser, Lys

()

1.

,----

- -

GPT + -

GOT -

S-GPT S-GOT

2. L-L- -

L-NAD+NADP+ GTPATP ADP

3.

PLP

(NH3) - () CO2 - CO2

1.(NH3)

(1) GlnGln,NH3

(2) --Ala

-Ala

2

H2O

Urea Biosynthesis -1 (carbamoyl phophate synthetase,CPS)

CPS-AGA(N-acetyl glutamatic acid,AGA)N--AGA

Urea Biosynthesis -2

Urea Biosynthesis -34

Urea Biosynthesis -5

NH4+ + CO2 + 3ATP + + 2H2O + 2ADP + 2Pi + AMP + PPi + 21CCO214NH3ITCA

-

TCA

5TCACoA-CoA

TCA P3152.-1. CoA4. 3. CoACoA5. TCAA

CoA,CoA- A

() CO2CO2

-ATCA

TCA ACO2H2OATP-CO2TCA

(one carbon unit, OCU) -CH3 -CH2--CH= CH=NH H-C0- -CH2OH- THF, FH4 S-50

FH4FH4FH4FH4N5N10

-

+ C

S-SAMSAM Met SAM

SAHcy

N5-CH3-FH4 N5-CH3-FH4

N5-CH3-FH4Hcy

S-ATP

5-5-

--(GABA)

-L-VB6

(taurine)

-NH2

GluAspSerHis

-1-

-2TCA-5-CoA

A