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Rand WaterImplementing methods in a Implementing methods in a
Hydrobiology Lab – Chlorophyll-α and Chlorophyll 665Chlorophyll-665
Presented by:I P bh iImraan Peerbhai
10 September 2013
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Presentation Outline1. Rand Water - Background2. Who is Analytical Services?3. Why Chlorophyll-α and 665?4. Process followed5 Challenges experienced5. Challenges experienced6. Screenshots of system7 Benefits to the lab7. Benefits to the lab8. Lessons learned9. Conclusion & way forwardy
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Rand Water - Background
• So who is Rand Water exactly?
• What do they do?
• Who are the customers?
• What area is covered?
• Where does the water come from?
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Rand Water – Background contd..
• How is the water treated?
• What about during the pumping process?
• How often are samples taken?
• Are there standards that you adhere to?
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Presentation Outline1. Rand Water - Background2. Who is Analytical Services?3. Why Chlorophyll-α and 665?4. Process followed5 Challenges experienced5. Challenges experienced6. Screenshots of system7 Benefits to the lab7. Benefits to the lab8. Lessons learned9. Conclusion & way forwardy
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Analytical Services
• Division within Scientific Services - part of the Operating P tf li t d b I f ti M tPortfolio – supported by Information Management
• Some numbers (month of March) :• Some numbers (month of March) : • Sampling points – 1 129• Samples taken – 22 289p• Analyses performed – 86 095• Results – 455 589• Instruments interfaced - 113
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Presentation Outline1. Rand Water - Background2. Who is Analytical Services?3. Why Chlorophyll-α and 665?4. Process followed5 Challenges experienced5. Challenges experienced6. Screenshots of system7 Benefits to the lab7. Benefits to the lab8. Lessons learned9. Conclusion & way forwardy
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Chlorophyll-α and Chlorophyll-665
• Significance of the Chlorophyll analysis
• Algal related water problems : Algae interferes with the purification process• Algae interferes with the purification process
• Algae results in water with bad taste, odour and colour• Trihalomethane pre-cursor and source of carbon forTrihalomethane pre cursor and source of carbon for
microbiological growth
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Presentation Outline1. Rand Water - Background2. Who is Analytical Services?3. Why Chlorophyll-α and 665?4. Process followed5 Challenges experienced5. Challenges experienced6. Screenshots of system7 Benefits to the lab7. Benefits to the lab8. Lessons learned9. Conclusion & way forwardy
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Process Followed
• Compilation of URD’s
• System development
• Testing and training
• Rollout to production
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Presentation Outline1. Rand Water - Background2. Who is Analytical Services?3. Why Chlorophyll-α and 665?4. Process followed5 Challenges experienced5. Challenges experienced6. Screenshots of system7 Benefits to the lab7. Benefits to the lab8. Lessons learned9. Conclusion & way forwardy
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Challenges
• Interfacing instruments
• Design – multiple options during brainstorming
• Linking reference monthly QC’s to daily batches
• Viewing of multiple components in a chart
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Challenges
• Pipettes
• The design of specification limits for pipettes had to accommodate the following requirements
• Pipettes are method specific
• Pipettes are categorised by volume
• Each pipette has limits for 10%, 50% and 100% of its capacity
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PTS and IAC• PTS = Proficiency Testing Scheme
• IAC = Inter-Analyst CompetencyIAC Inter Analyst Competency
• Rand Water runs the PTS (and internal IAC) for Chlorophyll-α and Chlorophyll 665
M l i E l > L bW i E l• Manual process using Excel -> LabWare using Excel
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PTS and IAC
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PTS and IAC
• Workflow:
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PTS and IAC
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Presentation Outline1. Rand Water - Background2. Who is Analytical Services?3. Why Chlorophyll-α and 665?4. Process followed5 Challenges experienced5. Challenges experienced6. Screenshots of system7 Benefits to the lab7. Benefits to the lab8. Lessons learned9. Conclusion & way forwardy
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Example User Interface• Batch creation
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Example User Interface• Create duplicate
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Example User Interface• Assigning samples to wells (Eliza - Microcystin)
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Presentation Outline1. Rand Water - Background2. Who is Analytical Services?3. Why Chlorophyll-α and 665?4. Process followed5 Challenges experienced5. Challenges experienced6. Screenshots of system7 Benefits to the lab7. Benefits to the lab8. Lessons learned9. Conclusion & way forwardy
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Benefits Realised• Ensuring QC’s done and comply to Quality manual – Stops
the process until all pre-requisites are completed
• Reduced amount of time spent on data entry
• Higher accuracy of data – finger faults eliminatedHigher accuracy of data finger faults eliminated
• All necessary QC’s included in the batch
• Flagging out-of-spec data
• Free up analysts to perform other lab tasksp y p
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Presentation Outline1. Rand Water - Background2. Who is Analytical Services?3. Why Chlorophyll-α and 665?4. Process followed5 Challenges experienced5. Challenges experienced6. Screenshots of system7 Benefits to the lab7. Benefits to the lab8. Lessons learned9. Conclusion & way forwardy
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Lessons Learned
• Thorough analysis of requirements before design is critical
• Design improved with every method implemented
• Thorough analysis and design improves• Thorough analysis and design improves
ease of use of solution for user
maintenance in future
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Presentation Outline1. Rand Water - Background2. Who is Analytical Services?3. Why Chlorophyll-α and 665?4. Process followed5 Challenges experienced5. Challenges experienced6. Screenshots of system7 Benefits to the lab7. Benefits to the lab8. Lessons learned9. Conclusion & way forwardy
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The Way Forward
• Continuous improvement of analysis and design t h itechniques
• Implement using built-in LabWare functionality or modules h iblwhere possible
• Accept that, sometimes (often, actually), LIMS Basic d l t i i it bl d t i b i ldevelopment is inevitable due to unique business rules
• Implement Plate Manager module and Enhanced Visual Workflows
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THANK YOUTHANK YOU