1. , . 1,2,3 Acetaminophen (paracetamol)POAdenosineIVAlbuterolNebulizedAlfentanilIVAminophyllineIVAmiodaroneIV 10-20 mg/kg 4 . 90 mg/kg/24 hr 50-100 g/kg bolus (max 250 g/kg) 0.15 mg/kg NSS 2 ml. 10-50 g/kg bolus 0.5-1 g/kg/min 5 mg/kg loading then 1 mg/kg/hr 10-12 g/ml 25 mcg/kg/min, then 5-IV15 mcg/kg/min(max 1.2g/24h) (total loading 4 mg/kg)Amrinone SVT Bronchospasm Analgesia BronchospasmResistant, re-entrant atrial and ventricular dysrhythmia Heart failure 5-15 mcg/kg/min AmpicillinIV50-100 mg/kgAprotininIV load10,000 unit test dose 2 million KIU / 70 kg 30 LoadEndocarditis prophylaxis bleeding celite ACT aprotininIV infusion500,000 KIU/ 70 kg/hr ( CPB ) 0.005-0.01 mg/kgAramineIVHypotensionAtracuriumIVAtropineIV0.6 mg/kg 5-10 g/kg/min infusion 0.01-0.02 mg/kg BupivacaineNerve blockMax 2-3 mg/kg/dose,Local anestheticsCalcium chlorideIV10% 0.2ml/kg bolus 0.03-0.12 ml/kg/hHypocalcemia

2. Calcium gluconateIVCefazolinIVCefoxicitinIVCefuroximeIVChloral hydratePO, PRCis-AtracuriumIV10% 0.5 ml/kg bolus 0.1-0.4 ml/kg/h 25 mg/kgHypocalcemia 25 mg/kg 25 mg/kg Sedation 50-75 mg/kg 0.1 mg/kg loading 0.03 mg/kg infusion 1-3 g/kg/minIV5-10 mg/kg q 6h IVCloxacillinIVover 1h 25-50 mg/kgCodeinePO IMClindamycin0.5-1 mg/kg ( analgesic drug dose) 1 mg/kg/min until improves(max 10 mg/kg), then 1-2 mg/kg/dose q6h for 1-3 day 0.3 g/kg (15 DantroleneIVMalignant hyperpyrexiaDDAVP (Desmopressin)IVDexamethasoneIV/PO0.1-0.25 mg/kg/dose stridor , ICPDiazepamIV0.1-0.4 mg/kgDigoxinIV/POSedation, Rx bladder spasm SVT , CHFDimenhydrinate (Dramamine) Diphenhydramine (Benadryl)) DobutaminePO/ IV/IM15 mcg/kg stat and 5 mcg/kg after 6h, then 35 mcg/kg/dose (usual max dose 200 mcg IV, 250 mcg Oral) 12h slow IV or Oral. Level 6h or more after dose :1.0-2.5 nmol/L 1-1.5 mg/kg/dose 4-6 h IV1-2 mg/kg/dose 6-8 hIV2-15 g/kg/min 6 mg/kg 5% D/W 20Heart failure platelet dysfunction) 3. ml 1 ml/hr = 5 g/kg/min DopamineIV1 ml/hr = 5 g/kg/min 2-15 g/kg/min 6 mg/kg 5% D/W 20Heart failureml EMLA creamTopicalEpinephrine (Adrenaline)IVSC NebulizedEphedrine EsmololIM/ IV/ SC IV 1 . 0.01 mg/kg 5 0.01-1 g/kg/min 0.12 mg 5% D/W 20 ml 1 ml/hr = 0.1 g/kg/min 0.01 mg/kg 0.5 ml 2.5 % NSS 2.5 ml IV 1:1000 0.5 ml /kg /dose ( 6 ml) 0.25-1 mg/kg/dose Cardiac arrest , hypotension Heart failure , anaphylaxisUpper airway edemaHypotension Induce bradycardia500 g/kg bolus then 50-200 g/kg/min infusion 0.2-0.3 mg/kg/dose BP EtomidateIVFurosemideIV1 mg/kg (6 mg/kg)FentanylIV Flumazenil (anexateIVGentamicinIV/IM1-5 mcg/kg/dose 0.5-2 mcg/kg/h 10-100 mcg/kg/dose ( analgesic drug dose) 5 mcg/kg q 1 min up to 40 mcg/kg then 2-10 mcg/kg/ h 5 mg/kg statGlucoseIVHypoglycemia-50% glucose 0.5 ml/kg orHypoglycemia, Hyperkalemia benzodiazepine endocarditis 4. 10% dextrose 2.5 ml/kg Hyperkalemia-50% glucose 2 ml/kg + RI 0.1 unit/kg 5-10 mcg/kg/dose ,GlycopyrrolateIVHydralazineIV/IMHydrocortisoneIV0.1-0.2 mg/kg stat then 4-6 mcg/kg/min 0.5-2 mg/kg/dose 6-8hHydroxycine (atarax)PO IM PO2 mg/kg/dose 6-8 h 0.5-1 mg/kg/dose 5-10 mg/kg/dose 4-8hIV0.01-0.1 g/kg/min BradycardiaIbuprofen (brufen) Isoproterenol (Isuprel)Insulin ,regularIVKetamineIV IMKetorolac Labetalol LidocainePO PO IV IV Nerve block0.12 mg/kg 5% D/W 20 ml 1 ml/hr = 0.1 g/kg/min 0.05-0.2 u/kg/dose 0.05-0.1 u/kg/h 1-2 mg/kg/dose 10-40 mcg/kg/min premed 2-3 mg/kg anesthesia 5-8 mg/kg 5-10 mg/kg/dose 0.2 mg/kg/dose 1-2 mg/kg/dose Max 1-1.5 mg/kg Max 4 mg/kg, with adrenaline 7 mg/kg Max 3 mg/kg 50% MgSO4 0.05-0.1 ml/kgMagnesium sulfateTopical spray IVMannitolIV0.25-0.5 g/kg/doseMethadoneIV, PO, SC, IMMetoclopramide (plasil) Methylprednisolone(solumedrol)IV, IM, PO0.1-0.2 mg/kg/dose 612h ( analgesic drug dose) 0.15-0.3 mg/kg/dose 6hIVAsthma: 0.5-1 mg/kg/dose 6h Sepsis: 30 mg/kg/dose once Spinal cord injuryHypertension Adrenal suppression asthma ,Hyperglycemia AnesthesiaAnalgesia Hypertension Local anestheticsHypomagnesemia, Torsades de pointes, refractory ventricular tachycardia or fibrillation , ICP AnalgesiaNausea, vomiting Asthma, sepsis, spinal cord injury 5. Naloxone (narcan)IV, IM, SC, IntratrachealNaproxen (Naprosyn) Neostigmine (prostigmine)PO(within 8 h): 30 mg/kg then 5 mg/kg/h 2 days 0.1-0.2 mg/kg/dose 0.5 mg/kg/dose 50 mcg/kgIV over 10 min then 0.25-0.75 mcg/kg/min 0.15 mg/kg/dose 5-15 mcg/kg/min infusion 0.05-0.1mg/kg 10-30 mcg/kg/h 0.5 mg/kg in 50 ml 1 ml/h = 10 mcg/kg 0.1 0.1-0.2 mg/kg 30-50 mcg/kg ( analgesic drug dose) Opiate intoxication: 0.1 mg/kg then 0.01 mg/kg/h IV Postop sedation: 0.002 mg/kg/dose repeat q 2 min, then 0.01 mg/kg/h IV 5-10 mg/kg/dose 8-12 hIV0.05-0.07 mg/kg/doseNifedipine (adalat) NitroglycerinPO, SLNitroprussideIV infusionNorepinephrineIV infusionOndansetronIV 1-10 mcg/kg/min 0.5-10 mcg/kg/min 0.05-0.5 mcg/kg/min Prophylaxis 0.15 mg/kg Midazolam MilrinoneIV, IM PO IVMivacuriumIVMorphineIV IV infusionIM EpiduralIV infusionPancuroniumPO IVPenicillinIVPethidineIV IMPhenoxybenzamineIVSedation Inotrope+pulmonary vasodilator half life 2-4 h narcotics 0.25-0.5 mg/kg 6-8 hTreatment 0.2 mg/kg 0.1-0.2 mg/kg 0.1 mg/kg then 0.02 mg/kg 25-50 mg/kg q 12-24 h 100 mg/kg single dose 0.5-1 mg/kg/dose 1-2 mg/kg/dose ( analgesic drug dose) 1 mg/kg over 1-4 h then 0.5 mg/kg/dose 8-12h half life 2-4 h 6. PhentolamineIVPotassiumIV Infusionover 1 h 0.1 mg/kg IV stat, then 5-50 mcg/kg/min 0.3 x BW x (4.5- serum Hypokalemia K) 0.5 mEq/kg/hr CVP Propofol (Diprivan)IVPropanolol (Inderal)IVProstaglandin E1IVBolus 2.5-3.5 mg/kg Infuse 7.5-15 mg/kg/h 0.02 mg/kg then 0.1 mg/kg 0.01-0.1 mcg/kg/minProtamineIV1 mg/100 u heparinRanitidine (Zantac)IV1 mg/kg/dose 6-8 hRemifentanilIVRocuroniumIVSalbutamol (ventolin)PO InhalationScopolamine (hyoscine) Sodium bicarbonateIM, IV1 mcg/kg over 30 sec then 0.05-0.2 mcg/kg/min ventilated: 1 mcg/kg then 0.5-4 mcg/kg/min 0.6-1.2 mg/kg then 0.1- 0.2 mg/kg or 5-15 mcg/kg/min 0.1-0.15 mg/kg/dose 6h Mild:0.5%0.5 ml dil 4 ml 3-6 h Moderate:0.5% 1 ml dil 4 ml 1-2 h Severe:0.5% undiluted continuously 0.01 mg/kg/dose 6h IVDose = BE x Wt/4 1 Sodium citratePO0.4 ml/kgSuccinylcholineIV IM1-2 mg/kgIV2-50 mcg/kg slow IV then 1 mcg/kg/h3-4 mg/kg Rx tachycardia patent ductus arteriosus , heparin hypotension pH metabolic acidosis pH malignant hyperthermiaSufentanil 7. ThiopentalIV2-5 mg/kgTolazolineIVPulmonary hypertensionTramadol(Tramol)IVVancomycinIV infusionVecuroniumIVVerapamilIV1-2 mk/kg then 2-6 mcg/kg/min 1-2 mg/kg/dose IV over 3 min then 2-8 mcg/kg/min 10 mg/kg dose infuse in 1 h : neonate q 8 h, infant & children q 6 h 0.1 mg/kg stat then 1-10 mcg/kg/min 0.1-0.2 mg/kg/dose over 10 min then 5 mcg/kg/min antibiotics SVT 1. Gronert B. Pediatric drug dose. In : Motoyama EK , Davis PG , ed. Smiths anesthesia for infants and children. St. Louis: Mosby , 1996: 937-40. 2. Steward DJ, Lerman J. Drug doses. In: Steward DJ, Lerman J, ed. Manual of pediatric anesthesia , 5th ed. New York : Churchill Livingstone , 2001: 521-7. 3. Cote CJ, Todres ID, Ryan JF, Goudsouzian NG. A practice of anesthesia for infants and children, 3rd ed. Philadelphia: WB Saunders, 2001. 4. Shann F. Drug doses, 10th ed. Melbourne : Royal Children Hospital , 2003.