2008

AminesQ 0120 Cobalt-Catalyzed Reductive Mannich Reactions of 4-Acryloylmorpholine with

N-Tosyl Aldimines. — The process affords the acyclic anti-β-aminoamides (III) as the major products. It complements existing syn-selective reactions and Morken's methol-ogy that gives β-lactams. It also shows higher diastereoselectivities compared with ex-isting anti-selective reductive Mannich reactions. — (PRIETO, O.; LAM*, H. W.; Org. Biomol. Chem. 6 (2008) 1, 55-57; Sch. Chem., Univ. Edinburgh, Edinburgh EH9 3JJ, UK; Eng.) — Kieslich

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