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![Page 1: ChemInform Abstract: Steric Tuning of Silylacetylenes and Chiral Phosphine Ligands for Rhodium-Catalyzed Asymmetric Conjugate Alkynylation of Enones](https://reader036.vdocuments.pub/reader036/viewer/2022080306/575003c71a28ab11489b0c3e/html5/thumbnails/1.jpg)
2008
C-C bond formationO 0282 Steric Tuning of Silylacetylenes and Chiral Phosphine Ligands for Rhodium-Cat-
alyzed Asymmetric Conjugate Alkynylation of Enones. — It is found that addition of the silylacetylene (III) to enones in the presence of the bulky phosphine (I) allows highly enantioselective formation of β-alkynylketones. These ketones are important building blocks. — (NISHIMURA*, T.; GUO, X.-X.; UCHIYAMA, N.; KATOH, T.; HAYASHI, T.; J. Am. Chem. Soc. 130 (2008) 5, 1576-1577; Dep. Chem., Grad. Sch. Sci., Kyoto Univ., Sakyo, Kyoto 606, Japan; Eng.) — Jannicke
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