![Page 1: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/1.jpg)
OsteoporosiLe dimensioni del problema in Italia
Gino Farchi
Laboratorio di Epidemiologia e BiostatisticaIstituto Superiore di Sanità
![Page 2: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/2.jpg)
ITALY - ISTAT DATALIFE EXPECTANCY at age 65 - MALES
ITALY - ISTAT DATALIFE EXPECTANCY at age 65 - MALES
12
12,7
13,8
2,9
2,7
2,5
0 5 10 15 20
1990
1994
1999
YEARS
Disability-free lifeexpectancyYears with disability
Fonte dei dati: ISTATISS-LEB-GF-2001
AA
16,3
15,4
14,9
![Page 3: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/3.jpg)
ITALY - ISTAT DATALIFE EXPECTANCY at age 65 - FEMALES
ITALY - ISTAT DATALIFE EXPECTANCY at age 65 - FEMALES
14,1
14,2
15,1
4,7
5
5,2
0 5 10 15 20 25
1990
1994
1999
YEARS
Disability-free lifeexpectancyYears with disability
Fonte dei dati: ISTATISS-LEB-GF-2001
20,3
19,2
18,8
![Page 4: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/4.jpg)
Cause primarie di DisabilitàCause primarie di Disabilità
• Osteoporosi e fratture• Malattie cardio e cerebrovascolari• Diabete• Artriti• Vista e udito • Deficit cognitivi
![Page 5: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/5.jpg)
Osteoporosi
Frequenti sedi di fratture‘…una condizione caratterizzata da diminuita massa ossea e deterioramento della microarchitettura del tessuto osseo, che comportano aumentata fragilità ossea e conseguente aumento del rischio di fratture
Femore prossimale
Polso
Vertebre
![Page 6: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/6.jpg)
Country Elderly index
Austria 88.27Belgium 91.27Denmark 84.64Finland 76.73France 80.15Germany 97.49Greece 100.08Ireland 49.98Italy 116.54Luxemburg 76.51Portugal 86.07Spain 98.86Sweden 92.89The Netherlands 72.83United Kingdom 81.46EU 15 91.28
Austria 88.27Belgium 91.27Denmark 84.64Finland 76.73France 80.15Germany 97.49Greece 100.08Ireland 49.98Italy 116.54Luxemburg 76.51Portugal 86.07Spain 98.86Sweden 92.89The Netherlands 72.83United Kingdom 81.46EU 15 91.28
Elde
rly in
dex
in 1
997
in t
he E
urop
ean
Uni
onEl
derly
inde
x in
199
7in
the
Eur
opea
n U
nion
![Page 7: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/7.jpg)
ITALY - AGEING INDEX BY REGIONS(PROMETEO ATLAS 2001)
ITALY - AGEING INDEX BY REGIONS(PROMETEO ATLAS 2001)
Ageing index (x 100)
0,0
50,0
100,0
150,0
200,0
250,0
Region
ePie
monte
Valle d'A
osta
Lomba
rdia
p.a. B
olzan
op.a
. Tren
toVen
eto
Friuli
Venez
ia Giuli
aLig
uria
Emilia
Romag
naTo
scan
aUmbri
aMarc
heLa
zioAbru
zzo
Molise
Campa
niaPu
gliaBas
ilicata
Calabri
aSicil
liaSard
egna Ital
ia
REGIONS
%
![Page 8: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/8.jpg)
Speranza di vita alla nascita in ItaliaSperanza di vita alla nascita in Italia
85.5
64.3
75.878.2
79.8
83.981.7
67.8
60
65
70
75
80
85
90
1950 2000 2025 2050
![Page 9: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/9.jpg)
AGEING IN ITALY
YEARS 2000 and 2030 Total population in 2000: 57298386
males | females | | | | | | | | | | | | | | | | | | | -
percentage of population
Age Total population in 2030: 49533430 | males | females
90+| | | |
80| | | |
70| | | |
60| | | |
50| | | |
40| | | |
30| | | |
20| | | |
10| | | |
0| | - percentage of population
Copyright © United Nations / Division for Social Policy and Development
![Page 10: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/10.jpg)
Percentuale di popolazione con 80+ anni. Percentuale di popolazione con 80+ anni. Confronti internazionaliConfronti internazionali
5.9
11.0
3.1
15.7
7.8
4.0
1.1 3.81.7
1.30.60.3
0
10
20
1950/55 2000/05 2025/30 2045/50
Italia M Francia India
![Page 11: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/11.jpg)
Fonti informative
Registri
Indagini campionarieIntervisteEsami obiettivi
Studi epidemiologici ad-hoc
![Page 12: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/12.jpg)
Mortalità per osteoporosi (ICD=733.0). ISTAT. Anno 1999
Età Uomini Donne
55-64 2 2
65-74 2 13
75-84 9 58
85 e più 7 107
Totale 20 180
![Page 13: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/13.jpg)
Health Interview Surveys (HIS)
In a national health interview survey (HIS) a sample of the general population is selected as a random sample of households and/or individuals. Trained interviewers are normally used, but there may also be some self-completed questionnaires. In some countries, continuous health surveys form part of a multi-purpose socio-economic surveys system. HIS typically cover topics like health status, life style and health habits, living and working conditions, health protection, and demographic and other social factors.
National health interview surveys (HIS) are regularly being carried out in 16 of the 18 EU/Efta Member States. Only in Greece and Luxembourg no HIS were reported.
![Page 14: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/14.jpg)
Health Interview Surveys (HIS)
Diagnoses are often underreported or overreported in HISs (Heliövaara et al 1991, Fisher et al 1996, Kasper 1998, ILSA 1997). Some diseases or conditions do not manifest through symptoms (e.g. hypertension, osteoporosis), the symptoms may be difficult to specify through responses to questions (e.g. visual or auditory acuity) or there is a recall bias (e.g.infections and immunisations). The results of physical examination and subjective reporting of pain and disability can differ substantially (Michel et al 1997). There is evidence of under-reporting weight and over- or under-reporting height in self-reports compared to actual measurements (Bolton-Smith et al 2000).
![Page 15: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/15.jpg)
Indagine ISTATCondizioni di salute e ricorso ai servizi sanitari
Per soddisfare i bisogni informativi a livello territoriale e consentire stime regionali e sub-regionali utili alla programmazione sanitaria locale, nel 1999/2000, èstata notevolmente ampliata la numerositàcampionaria grazie al contributo del Fondo Sanitario Nazionale su mandato della Conferenza Stato-Regioni.Ogni tre mesi è stato intervistato un quarto del campione complessivo di 52.300 famiglie, per un totale di circa 140.000 individui, distribuiti in 1.449 comuni.
![Page 16: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/16.jpg)
Patologie croniche dichiarate su 1000 intervistati con età 65 anni e più.
ISTAT - Indagine "Condizioni di salute" 1999-2000.
0 50 100 150 200 250 300 350 400 450 500 550 600
Diabete
Cataratta
Ipertensione
Vene varicose, varicocele
Bronchite cronica, enfisema, ins. respiratoria.
Artrosi, artrite
Lombosciatalgia
Osteoporosi
Ipertrofia prostata
Cefalea o emicrania ricorrente
Parkinson, Alzheimer, epil.,
Uomini Donne
![Page 17: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/17.jpg)
Prevalenza di osteoporosi dichiarata. Anni 1999-2000.(per 100 persone della stessa classe di età e sesso)
Indagine ISTAT sulla salute, 1999-2000
0,68 1,632,85
4,065,4
6,485,39
16,81
21,59
26,69
29,1630,59
0
5
10
15
20
25
30
35
45-54 55-64 65-69 70-74 75-79 80 e più
classi di età
perc
entu
ale
Uomini Donne
![Page 18: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/18.jpg)
0102030405060
Prevalenza per 1000
Aree
Osteoporosi dichiarataIndagine ISTAT 1999-2000
Nord-OvestNord-EstCentroSudIsoleItalia
![Page 19: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/19.jpg)
010203040506070
Prevalenza per 1000
Comuni
Osteoporosi dichiarataIndagine ISTAT 1999-2000
Aree metrop.Periferia metr.50.000 e più10,000-50.0002000-10.000meno di 2000
![Page 20: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/20.jpg)
Health Examination Surveys (HES)
Health examination surveys (HES) involve physical examinations, clinical and laboratory tests and various other technical/psychological measurements/tests. A central battery of tests and assays for HES includes anthropometric measurements, physical examination results (including assessment of disability), interview, and a laboratory component. HESs attempt to accurately measure the prevalence of selected diseases, conditions and risk factors. HESs can provide continuous monitoring of many physical, physiological and psychological characteristics of a population.
![Page 21: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/21.jpg)
Health Examination Surveys (HES) in EU
National population based HESs with a comprehensive focus have been conducted at regular or irregular intervals in five countries (Finland, Germany, Ireland, the Netherlands and UK) and in a large region in one country (Catalonia, Spain). In these countries several local, regional and/or focused surveys have been carried out previously or in parallel to the national HESs. All of these national HESs include a HIS component preceding or parallel to the HES. National surveys in the planning or pilot stage were identified in four countries (France, Italy, Norway, and Sweden) and there are some preliminary plans for a national survey in one more country (Portugal).
![Page 22: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/22.jpg)
La salute a Firenze
Studio pilota per un indagine di tipo HES in Italia
Collaborazione: ISS – ISTAT – ARS della Toscana – ASL di Firenze
Popolazione oggetto dello studio: soggetti di 35-74 anni appartenenti alle 476 famiglie del campione ISTAT.
![Page 23: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/23.jpg)
Prevalenza di Osteopenia ed OsteoporosiPopolazione femminile.
Studio “Salute a Firenze”
62,20% 33,80% 4%
28,40% 54,90% 16,70%
20,50% 31,80% 47,70%
36,70% 41,90% 21,40%
0% 20% 40% 60% 80% 100%
40-49
50-59
60-69
Tutti
prev
alen
za r
elat
iva
NormaleOsteopeniaOsteoporosi
(
![Page 24: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/24.jpg)
Osteoporosi
Osteoporosi HES (dom.)
Osteoporosi HIS si no Totale
si 8 3 11
no 5 311 316 Totale 13 314 327
Osteoporosi HES ( esame)
Osteoporosi HES ( dom.) si no Totale
si 8 9 17
no
26 367 393 Totale 34 376 410
Osteoporosi HES ( esame)
Osteoporosi HIS si no Totale
si 3 7 10
no 20
281 301 Totale 23 288 311
Sensibilità 61,54
Specificità 99,04Misura di concordanza: K 0.654*
Sensibilità 25Specificità 97,51Misura di concordanza: K
0.274*
Sensibilità 13,04Specificità 97,57
Misura di concordanza: K 0.143*
* Valori di K significativi al livello di p< 0.05
![Page 25: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/25.jpg)
CONFRONTI HES-HIS
HES HIS HES-HIS (*) p (°)
Uomini 80.95 79.02 1.93 0.000Donne 61.84 60.38 1.46 0.000Uomini 174.22 176.17 -1.95 0.000Donne 161.71 163.65 -1.94 0.000Uomini 26.73 25.50 1.23 0.000Donne 23.66 22.54 1.12 0.000
(*) Media delle differenze (Osservazione Hes - Osservazione His )
(°) Significatività del test T per campioni appaiati
Peso
Altezza
BM I
Valori Medi di Variabili Antropometriche
![Page 26: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/26.jpg)
E.S.O.P.O.
EpidemiologicalStudy
On the Prevalence of
Osteoporosis
![Page 27: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/27.jpg)
Membri del Comitato di coordinamento dello studio ESOPO:
Prof. Adami (Università di Verona)Prof. Crepaldi (Università di Padova) Prof.sa Di Munno (Università di Pisa) Prof. Isaia (Università di Torino)Prof. Filipponi (Università di Perugia) Prof.sa Maggi (Università di Padova)Prof. Menotti (Roma)
![Page 28: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/28.jpg)
Obiettivi dello studioObiettivi dello studio
Primario:Determinare la prevalenza della malattia osteoporosi nella popolazione italiana generale
donne: 40-79 anniuomini: 60-79 anni
Secondario:Identificare fattori clinici e di stile di vita significativamente associati all’osteoporosi
![Page 29: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/29.jpg)
Strumento
Lunar Achilles Express
•Ultrasonometria Ossea a livello del calcagno
![Page 30: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/30.jpg)
CATEGORIECATEGORIE
Indice di Stiffness
Normale > 86%
Osteopenia > 65% e <86%
Osteoporosi < 65%
![Page 31: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/31.jpg)
Prevalenza di Osteopenia ed OsteoporosiPopolazione femminile in Italia
Studio E.S.O.P.O.
52.8 37.8 9.4
40.0 44.2 15.8
23.0 44.8 32.1
14.0 40.3 45.7
34.9 42.3 22.8
0% 20% 40% 60% 80% 100%
40-49
50-59
60-69
70-79
Tutti
prev
alen
za r
elat
iva
NormaleOsteopeniaOsteoporosi
![Page 32: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/32.jpg)
Prevalenza Osteopenia ed OsteoporosiPopolazione maschile in Italia.
Studio E.S.O.P.O.
53.9 34.3 11.8
50.8 35.1 14.1
47.9 34.3 17.9
48.7 33.0 18.3
51.2 34.3 14.5
0% 20% 40% 60% 80% 100%
60-64
65-69
70-74
75-79
Tutti
prev
alen
za re
lativ
a
NormaleOsteopeniaOsteoporosi
![Page 33: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/33.jpg)
Numero di donne con osteoporosi in Italia. Studio Esopo
0 1000000 2000000 3000000 4000000 5000000
2000
2025
40-49 50-59 60-69 70-79 80+
N= 4.690.000
N= 3.928.000
![Page 34: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/34.jpg)
Fratture d’Anca, Donne, Storia PersonaleStudio E.S.O.P.O.
p<0.0001
p<0.001 p=0.0012.5
0
0.5
1
1.5
2
% d
i paz
ient
iSt
anda
rdiz
zata
per
eta
’
Normale Osteopenia OsteoporosiN=2093 N=3299 N=1656
![Page 35: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/35.jpg)
Fratture d’Anca, Uomini, Storia PersonaleStudio E.S.O.P.O.
p<0.0001
p<0.01 p=0.063.5
0
0.5
1
1.5
2
2.5
3
% d
i paz
ient
iSt
anda
rdiz
zata
per
eta
’
Normale Osteopenia OsteoporosiN=2338 N=1586 N=442
![Page 36: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/36.jpg)
Fratture Vertebrali, Donne, Storia PersonaleStudio E.S.O.P.O.
p<0.0001
p=0.01 p=0.0014
0
1
2
3
% d
i paz
ient
iSt
anda
rdiz
zata
per
eta
’
Normale Osteopenia OsteoporosiN=2093 N=3299 N=1656
![Page 37: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/37.jpg)
Fratture Vertebrali, Uomini, Storia PersonaleStudio E.S.O.P.O.
p<0.01
0
1
2
3
4
5
Normale Osteopenia Osteoporosi
p<0.05
% d
i paz
ient
iSt
anda
rdiz
zata
per
eta
’
N=2338 N=1586 N=442
![Page 38: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/38.jpg)
Esiti delle fratture del femoreEsiti delle fratture del femore
– Mortalità: in fase acuta 5%, ad un anno 15-25%
– Meno di metà dei pazienti cammina autonomamente dopo un anno
– Nel 20% l’abilità a camminare è persa completamente
– Solo 30-40% riacquista autonomia nelle ADL
![Page 39: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/39.jpg)
Conclusioni I• L’invecchiamento della popolazione comporta di
per sé un aumento del numero assoluto delle fratture
• E’ inoltre documentato un aumento dell’incidenza delle fratture del femore da 1-3% ogni anno
• La ricerca epidemiologica, oltre a fornire dati sulla dimensione del problema, identifica i soggetti ad alto rischio, per i quali interventi di prevenzione sono altamente efficaci, anche in termini economici
![Page 40: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/40.jpg)
Conclusioni II• L’Osteoporosi è sotto-diagnosticata e sotto-
trattata
• Anche il sesso maschile e’ coinvolto
• L’osteoporosi non trattata comporta dolore e sofferenza evitabili, aumenta la mortalità ed ha pesanti conseguenze sociali ed economiche
• Sono necessari programmi di sensibilizzazione ed informazione diretti ai medici, ai pazienti e in generale all’intera popolazione
![Page 41: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/41.jpg)
2
12
1
4
2
8
2
5
349
7
7
4
7
1
7
Numero di Centri per Regione
![Page 42: Osteoporosi Le dimensioni del problema in Italia osteoporosi.pdf · italy - istat data life expectancy at age 65 - males italy - istat data life expectancy at age 65 - males 12 12,7](https://reader033.vdocuments.pub/reader033/viewer/2022060314/5f0b93757e708231d4313122/html5/thumbnails/42.jpg)
FINE