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OVIDSP MEDLINE**

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treatment for childhood obesitySearch AidBasic Search (5

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Ovid Medline*OvidEBM

Search ToolsMap TermTreeThesaurusPermuted IndexScope NoteExplodeSubheadingsClassification CodesSearch FieldsFloating Sub-Heading (FS)Exploded Sub-Heading (XS)

Advanced Ovid Search Map Term to Subject Heading

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Search ToolsMap TermAdvanced Ovid SearchMap Term to Subject HeadingTreeThesaurusBroader TermNarrow TermRelated TermUsed-for TermsPermuted IndexRelated termsUsed-for termsScope NoteExplodeSubheadingsClassification Codes*

Tree*Bone cancer

Thesaurus*Anxiety

Permuted Index*obesity

ClassificationCodes*

Search Fields(Subheadings in Medline)SubHeadingMeSHSubject Heading83(http://www.nlm.nih.gov/mesh/topsubscope2008.html)2NursingNUMeSHSearch FieldsFloating Sub-Heading (FS)Exploded Sub-Heading (XS)31ae.xsAdverse EffectsPoisoningToxicity

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*MeSHMeSH

Floating Sub-Heading*a83

Exploded Sub-Heading*31

-heart.tititleheartaspirin.ab,shMeSHaspirin..l/5 yr=2000-20042000-2004root steve.austeve..pg 5-85~8..ps*

-$*depress $depress, depressive, depressants, depressorrat$rat , rate, rationalize, ratifydog$1 dog, dogsdogma#? 2wom#n womanwomen dog# dogsdogcolo?r color, colourdog? dog, dogs

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OR(pregnancy or birth).ti.1 or 2 or 3 or 5or/1,2,3,5or/1-3,5AND(pregnancy and birth).ti.1 and 2 and 3 and 5and/1,2,3,5and/1-3,5Not(education not patient education).ti.safety not patient safety.ti.safety.mp not patient safety.tisafety not patient safetysafety.mp not patient safety.mp1 not 2AdjNphysician adj5 relationship(information adj3 retrieval).tw.Freqblood pressure.ab./freq=10 (information adj3 retrieval).tw./freq=5SOFreq.

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heart.ti,ab1.heart.ti,abheart1.ti2.heart.ti1attack.ti3.attack.tiattack2 adj5 34.heart adj5 attack.ti230~5dogs.ab5.dogs.abdogscats.ab6.cats.abcats5 or 67.5 or 6dogscats7.ti8.(dogs or cats).tidogscatsjama.so9.jama.sojama9.pg10.jama.pg99.pg9jama9.pg11.9.pg

Ovid MedlineOvidEBM

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OvidEBMPICO PICO Map Term to Subject HeadingMeSH LimitAdditional LimitEBM ReviewsOvid EBMRClinical QueriesPublication Type(MeSH*

PICOThe Centre for Evidence-Based MedicineThe National Library for Health, NHSCarl HeneghanPaul GlasziouQuesions Log: A tool for ' just in time' learning

1a: systematic review on multiple RCTs1b: well designed, analyzed, RCT1c: all or none2a: systemic review on several cohort studies2b: cohort study, poor designed RCT2c: outcomes research; ecological studies3a: systemic review on several case-control studies3b: case-control study4: one hospital experience, poor designed cohort or case-control studies5: personal opinions, bench, animal data

53protonpump inhibitor

PICOPICOP53 y/o man ,ulcer bleedingIProton pump inhibitorCH2 blocker, antacid, no useORebleeding , morbidity, mortalitySpecific Question:For a 53 year old man with ulcer bleeding, how effective is the proton pump inhibitor compared to other treatment?Keyword/MeSHMajor subjectUlcer bleeding, PPIOther subjectendoscopyLimitMiddle age, Male

Ovid EBMR +Ovid MedlineOvid EBMRTopic ReviewsCochrane CollaborationCochrane Database of Systematic Reviews (CDSR)Cochrane Database of Methodology Reviews (CDMR)NHS Centre for Reviews and Dissemination (CRD)The Database of Abstracts of Reviews of Effectiveness (DARE)Health Technology Assessments (HTA) NHS Economic Evaluation Database (NHSEED)Article ReviewsAmerican College of PhysiciansACP Journal Club The Database of Abstracts of Reviews of Effectiveness (DARE)Definitive Controlled TrialsCochrane CollaborationCochrane Central Register of Controlled Trials Methodology ReviewsCochrane CollaborationCochrane Methodology Register (CMR)Ovid Medline*

MeSHMeSH TreeMeSH TreegenericspecificFocusExplodeSubHeading()

LimitClinical QueriesPublication Type

Clinical QueriesPurpose categoryTherapyDiagnosisPrognosisReviewsClinical prediction guidesQualitativeEtiologyCostsEconomicsOptimizationsensitivityspecificityoptimized

sens = ; spec = ; prec = ; acc =

Strategy TypeOptimizationSens / spec / prec / acc(%)Ovid SyntaxTherapySensitivity99 / 70 / 10 / 71clinical trial.mp. OR clinical trial.pt. OR random:.mp. OR tu.xsSpecificity93 / 97 / 54 / 97randomized controlled trial.pt. OR randomized controlled trial.mp.Optimized96 / 95 / 39 / 95randomized controlled trial.pt. OR randomized.mp. OR placebo.mp.DiagnosisSensitivity99 / 74 / 1 / 74sensitiv:.mp. OR diagnos:.mp. OR di.fs.Specificity65 / 98 / 11 / 98specificity.tw.Optimized93 / 92 / 3 / 92sensitiv:.mp. OR predictive value:.mp. OR accurac:.tw.PrognosisSensitivity90 / 80 / 2 / 80incidence.sh. OR exp mortality OR follow-up studies.sh. OR mortality.sh. OR prognos:.tw. OR predict:.tw. OR course:.tw.Specificity52 / 94 / 3 / 94prognos:.tw. OR first episode.tw. OR cohort.tw.Optimized83 / 84 / 2 / 84prognosis.sh. OR diagnosed.tw. OR cohort:.mp. OR predictor:.tw. OR death.tw. OR exp models, statistical


Strategy TypeOptimizationSens / spec / prec / acc(%)Ovid SyntaxReviewsSensitivity99.9 / 52 / 3 / 53search:.tw.OR meta analysis.mp,pt.OR review.pt.OR di.xs. OR associated.tw.Specificity71 / 99.2 / 57 / 99MEDLINE.tw.OR systematic review.tw.OR meta analysis.pt.Optimized98 / 91 / 14 / 91meta analysis.mp,pt.OR review.pt.OR search:.tw.Clinical Prediction GuidesSensitivity96 / 79 / 1 / 79predict:.mp. OR scor:.tw. OR observ:mp.Specificity54 / 99 / 12 / 99validation.tw. OR validate.tw.Optimized90 / 90 / 2 / 90predict:tw. OR validat:.mp. OR develop.tw.Qualitative StudiesSensitivity95 / 70 / 2 / 70interview:.tw. OR px.fs. OR exp health services administrationSpecificity61 / 99 / 37 / 99qualitative.tw. OR themes.tw.Optimized92 / 92 / 7 / 92interview:.mp. OR experience:.mp. OR qualitative.tw.


Strategy TypeOptimizationSens / spec / prec / acc(%)Ovid SyntaxEtiologySensitivity93 / 63 / 2 / 63risk:.mp. OR exp cohort studies OR between group:.tw.Specificity51 / 95 / 6 / 95relative risk:.tw. OR risks.tw. OR cohort stud:.mp.Optimized83 / 83 / 3 / 83risk.mp. OR mortality.mp. OR cohort.tw.CostsSensitivity100 / 96 / 13 / 96ec.fs. OR cost.tw. OR health care costs.sh.Specificity57 / 99.5 / 37 / 99cost effectiveness.tw. OR health care costs.sh.Optimized98 / 98 / 18 / 98exp "costs and cost analysis" OR costs.tw. OR cost effective:.tw.EconomicsSensitivity100 / 94 / 1 / 94randomized controlled trial.pt. OR cost effectiveness.tw. OR cost effective.tw.Specificity51 / 99.4 / 6 / 99cost effective.tw. OR sensitivity analys:.tw.Optimized97 / 96 / 2 / 96cost:.mp. OR cost benefit analys:.mp. OR health care costs.mp.

EBM*The Evidence Pyramid modified from "Navigating the Maze", University of Virginia, Health Sciences LibraryThe Evidence Pyramid is from Guide to Research Methods

Ovid MedlineOvidEBM

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**********************PICOPICO* + 5W1H (who, what, why, when, where, how ) + COX-II COX-II Foreground question 1. 1. Clinical findings (e.g. History or Pysical Finding of a patient) 2. Etiology / Harm ( ) 3. Dx / DDx ( ) 4. Prognosis () 5. Rx / Prevention ( ) 2. P I C O PICO ********Our Clinical Hedges database contains data for the year 2000 for each article in each of the issues of 170 clinical journals. 161 of these journals were indexed in MEDLINE. **********

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