Pedigree Analysis
1. The following pedigree shows inheritance of dwarfism in on family. Dwarfism is an autosomal, dominant trait (D), while normal height is recessive (d). Determine the likely genotypes of the individuals in the pedigree.
2. The pedigree below depicts the inheritance of albinism, an autosomal, recessive trait. Determine which individuals in the family below must be carriers of the albinism allele.
3. The following pedigree is for Huntington’s Disease, which is inherited as an autosomal, dominant trait. Determine the genotypes of the individuals in the pedigree.
I II III
4. This pedigree indicates the occurrence of hitchhiker’s thumb. a. Based on the evidence provided in the pedigree, is hitchhiker’s thumb
dominant or recessive? b. What evidence supports your answer in “a” above?
5. On a separate sheet of paper, construct a pedigree that shows recessive inheritance (i.e. diabetes).
a. Include at least 3 generations b. Include at least 15 individuals c. Include at least 4 individuals who have the disorder d. Indicate all carriers
I
II
III IV
1 2
1 2 3 4
2 1
1 2 3
3 4