Transcript
![Page 1: Protein(Structural(Metrics(for( Modelling(Presentation1.pptx Author M.Shajahan Gulam Razul Created Date 7/16/2015 4:02:23 PM](https://reader033.vdocuments.pub/reader033/viewer/2022052719/5f07bdf87e708231d41e833f/html5/thumbnails/1.jpg)
Protein Structural Metrics for Modelling
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• The 20 standard amino acids share a common structure but differ in their side chains. • Pep=de bonds link amino acid residues in a polypep=de.
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General Structure of α-Amino Acid
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Condensation of Two Amino Acids
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Condensation of Two Amino Acids
Pep=de Bond
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1°, 2°, 3° & 4° Structure
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Peptide Bonds Assume Trans Conformation
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Resonance of Peptide Bond
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Extended Conformation of Polypeptide
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Torsion Angles of Polypeptide Backbone
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Steric Interference of Adjacent Peptide Groups
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The α Helix
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β Sheets
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Antiparallel β Sheet
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Ramachandran Diagram
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Parallel β Sheet
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Pleating of β Sheet
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