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Page 1: Ras-raf- MEK

Ras-raf-MEK

AKT

PI3K

PTEN

mTOR

TSC2 TSC1

LKB1

AMPK

TORC1

TORC2mTOR

mTORC1/2 inhibitors

Tyrosine kinase inhibitors

AKT inhibitors

Metformine

Rapalogs:Everolimus

Temsirolimusridaforolimus

PI3K inhibitors

PI3K dependent pathway

AMPK-dependentPI3K independent pathway

ENERGY PATHWAY

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