Download - Sndrome de goodpasture karen rdz mora
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![Page 1: Sndrome de goodpasture karen rdz mora](https://reader035.vdocuments.pub/reader035/viewer/2022062513/556e9395d8b42ad7458b4aec/html5/thumbnails/1.jpg)
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Síndrome reconocido por primera vez por Goodpasture en 1919
Paciente de 18 años con hemoptisis y proteinuria
Bien tipificada
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Glomerulonefritis asociada a anti-MBG
Daño simultaneo del riñón y pulmón
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Se presenta en 50-60% de los casos con glomerulonefritis por AB anti-MBG
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Hemoptisis aguda o recurrente
Hematuria
Proteinuria
Síndrome nefrótico
Inicio de los síntomas IR 3-4
semanas
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Se manifiesta principalmente por : Glomerulonefritis rápidamente
progresiva
Insuficiencia renal
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Estudio histopatológico
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Inmunofloresencia
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Forma rápida
Se encuentran positivos en la mayoría de los casos
Detección de ab anti-MBG
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El 15 % presentan ANCA-p positivos
Síndromes renopulmonares
Ab anti-MBG
ANCA-pANCA-c
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Metilprednisolona HP
Esteroides
Ciclofosfamida 1-2 mg/kg dosis diaria matutina