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Page 1: Supplementary Figure 1

A

C

Supplementary Figure 1

CAF1 CAF2 CAF3 CAF40%

20%

40%

60%

80%

100%

rate of FAP expression

CAF1: CTRL CAF1: FAP

CAF2: CTRL CAF2: FAP

95.52%

99.81%

B

CAF4: PDPN

CTRL 2min

5min 10min

14.38%

13.87%13.48%

- 2 5 10 2 5 10 2 5 10 2 5 100%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

rate of PDPN expression

Time of trypsin/EDTA treatment (min)

CAF1

CAF2 CAF3 CAF4

CAF1 CAF2 CAF3 CAF4

Cultured CAFs

Harvested CAFs

CAF1 CAF2 CAF3 CAF4

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Supplementary Figure 2